In A Climate of History Dipesh Chakrabarty locates Kant’s speculative reading of Genesis as “the Enduring Fable” furnishing the background for human domination and earthly destruction. Writing from the fable’s “ruins,” Chakrabarty urges the elaboration of new fables that provide the background ethics and meanings required to recast relations between humans and the natural world. Responding to Chakrabarty’s challenge, we outline two “fables” based first in the oft ignored Genesis 2, and second, in Matauranga Māori. Although marginalised, these extant fables (...) provide the imaginary for radically other ways of being human in a more-than-human world in turmoil. (shrink)

The idea of dignity is often taken to be a foundation for principles of justice and democracy. In the West it has numerous formulations and conceptualisations. Within the capabilities approach to justice theorists have expanded the concept of dignity to encompass animals and ecological communities. In this article I rework the idea of dignity to include the Māori philosophical concepts of Mauri, tapu and mana – something I argue is necessary if the capabilities approach is to decolonise in the Aotearoa (...) context. Furthermore, the article links the nation’s recognition of three extensive geographical regions – Te Awa Tupua, Te Urewera and Mt Taranaki – as legal persons to Mātauranga Māori and nonhuman dignity. In doing so, I identify the potential that this understanding of dignity and these legal moves have to decolonise democracy within the settler state. (shrink)

Karen Warren has argued that environmental ethics must be feminist and that feminist ethics must be ecological. Hence, she endorses ecofeminism as an environmental ethic with power and promise. Recent ecofeminist theory, however, is not as powerful as one might hope. In fact, I argue, much of this theory is based on values that are potentially damaging to moral agents, and that are not in accord withfeminist goals. My intent is not to dismantle ecofeminism, but to analyze and clarify some (...) of the philosophical problems with recent ecofeminist work and to point out a more promising direction for ecofeminist ethics. (shrink)

The Eleatic Visitor speaks forcefully when he insists, ‘Necessarily, whenever there is speech, it is speech of something; it is impossible for it not to be of something’. For ‘if it were not of anything, it would not be speech at all; for we showed that it is impossible for there to be speech that is speech of nothing’. Presumably, at 263c10, when he claims to have ‘shown’ that it is impossible for speech to be of nothing, the Visitor is (...) referring back to the Parmenidean puzzles at Sophist 237ff. (shrink)

According to Aristotle, Plato's efforts at metaphysical explanation not only fail, they are nonsensical. In particular, Plato's appeals to Forms as metaphysically explanatory of the sensibles that participate in them is "empty talk" since "'participating' means nothing". I defend Plato against Aristotle's charge by identifying a particular, substantive model of metaphysical predication as the favored model of Plato's late ontology. The model posits two basic metaphysical predication relations: self-predication and participation. In order to understand the participation relation, it is important (...) first to understand how Plato's Forms are self-predicative paradigms. According to the favored model, Forms are self-predicative paradigms insofar as they are ideal, abstract encoders of structural essences. Sensibles participate in Forms by exemplifying the structures encoded in the Forms. Given plausible conditions on metaphysical explanation, Plato's appeals to abstract Forms as metaphysically explanatory of sensibles is a reasonable competitor for Aristotle's appeals to natural, substantial forms. At the very least, Plato's appeals to a participation relation are not empty. (shrink)

The interlocutors of Plato’s Cratylus agree that “it is far better to learn and to inquire from the things themselves than from their names”. Although surprisingly little attention has been paid to these remarks, at least some commentators view Plato as articulating a preference for direct, nonlinguistic cognitive access to the objects of inquiry. Another commentator takes Plato simply to recommend first-hand, yet linguistic, experience in addition to instruction from experts. This paper defends, in contrast to both interpretations, the view (...) that inquiry without names is dialectical, linguistic inquiry into metaphysical first principles. As such, inquiry without names is prior to inquiry from or through names. Inquiry without names is a form of transcendental metaphysics. (shrink)

ABSTRACT Early in Plato’s Euthydemus, sophistical arguments threaten the intelligibility of the process of learning. According to M. M. McCabe, Socrates resists the sophists’ arguments by resisting their problematic replacement model of change. The replacement model proposes that one item (e.g., an unlearned one) is simply replaced with a nonidentical item (e.g., a learned one). Socrates is said to endorse a rival metaphysics of temporally extended, teleologically structured activities. The rival model allows an enduring subject to survive ‘aspect changes’ by (...) occupying distinct stages in a continuous, unified process. McCabe may be right that Socrates presupposes or favors a metaphysics of continuous, end-oriented activities. If so, there are independent reasons to strive to understand the teleological structure of the activity of learning. Nevertheless, I am not convinced that Socrates relies on such a metaphysics to resist the learning arguments at 275d—278d. I argue that Socrates appeals, instead, to the complexity of the learning process to recognize two distinct, yet related, uses of the term ‘learning.’ In order to resist the sophists’ arguments, Socrates recommends attending to ‘the correctness of names’. Socrates’s disambiguating response is sufficient to dissolve the sophistical arguments while remaining compatible with a variety of metaphysics of individuals and activities. (shrink)

In this dissertation I explore Plato's views about the nature of language and thought, and their relations to the world. Plato is sometimes thought to hold that meaningful terms do not require referents at all. Others argue that he holds a referential theory of meaning according to which the meaning of a term just is its referent. I reject both of these views, arguing that Plato thinks that a significant term must have a referent but that the referent of a (...) term does not exhaust its signification: there is also a descriptive component. On my view, Plato embraces a mixed account according to which naming and thought are descriptive and object dependent. Moreover, according to Plato, language is prior to thought, and the way the world is---what objects there are---ultimately determines what we can talk and think about. ;I focus on the Cratylus, Theaetetus and Sophist, the dialogues in which Plato develops his most sophisticated discussions of language and thought. In the Cratylus , Plato articulates an account of the signification of names, and he reveals his views about the nature and role of nominal definitions---the clusters of descriptions that linguistically competent speakers have in mind when they use terms from their language. A name signifies a nominal definition by convention; it signifies a real nature by nature. Plato defends an account of the necessary conditions on thought in the Theaetetus where the account of thought Plato ultimately embraces is not, as some have argued, a form of Russellian acquaintance. For Plato, thought is object dependent and at the same time conceptual. The commitment to object dependence and to the fundamental status of the world is evident in all three dialogues, but it is only explicitly defended in the Sophist. Plato argues that discourse and thought are hostage to what there is. Actual, countable objects determine the possible contents of language and thought. (shrink)

This chapter contains sections titled: Introduction The Metaphysics of Action The Explanation of Action The Psychology of Action References.

The Cratylus contains Plato's most extensive study of the relation of language to reality and to the pursuit of wisdom. Yet the dialogue has remained relatively neglected in efforts to understand Plato's deepest metaphysical and epistemological commitments. The blame for such neglect lies largely in the dialogue's extensive, difficult, even mysterious etymological section. Recent attempts to make sense of the bulk of the Cratylus are shedding much welcome light on the important roles that the etymological analyses play in the dialogue (...) and in Plato's philosophy more generally. The article outlines three strategies of interpretation before concluding with the author's own proposal. (shrink)

Despite societal concerns about the welfare of commercial laying hens, little attention has been paid to the welfare implications of the choices made by the genetics companies involved with their breeding. These choices regarding trait selection and other aspects of breeding significantly affect living conditions for the more than 7 billion laying hens in the world. However, these companies must consider a number of different commercial and societal interests, beyond animal welfare concerns. In this article we map some of the (...) relevant dilemmas faced by genetics companies in order to outline the scope of opportunities to improve welfare under current market conditions. This includes identifying cases where different animal welfare concerns conflict. We discuss the moral responsibility of laying hen genetics companies and the welfare implications that derive from the choices they make and the policies they follow. In addition to evaluating a selection of predominant current practices and breeding goals, we outline different angles from where to assess the moral legitimacy of various industry practices and policies. We discuss specific issues such as injurious pecking, bone health, induced moulting, chick culling and the circumstances of breeding stock. (shrink)

Unlimited paid time off policies are currently fashionable and widely discussed by HR professionals around the globe. While on the one hand, paid time off is considered a key benefit by employees and unlimited paid time off policies are seen as a major perk which may help in recruiting and retaining talented employees, on the other hand, early adopters reported that employees took less time off than previously, presumably leading to higher burnout rates. In this conceptual review, we discuss the (...) theoretical and empirical evidence regarding the potential effects of UPTO on leave utilization, well-being and performance outcomes. We start out by defining UPTO and placing it in a historical and international perspective. Next, we discuss the key role of leave utilization in translating UPTO into concrete actions. The core of our article constitutes the description of the effects of UPTO and the two pathways through which these effects are assumed to unfold: autonomy need satisfaction and detrimental social processes. We moreover discuss the boundary conditions which facilitate or inhibit the successful utilization of UPTO on individual, team, and organizational level. In reviewing the literature from different fields and integrating existing theories, we arrive at a conceptual model and five propositions, which can guide future research on UPTO. We conclude with a discussion of the theoretical and societal implications of UPTO. (shrink)

While outcomes for children with T-cell acute lymphoblastic leukemia have improved dramatically, survival rates for patients with relapsed/refractory disease remain dismal. Prior studies indicate that glucocorticoid resistance is more common than resistance to other chemotherapies at relapse. In addition, failure to clear peripheral blasts during a prednisone prophase correlates with an elevated risk of relapse in newly diagnosed patients. Here we show that intrinsic GC resistance is present at diagnosis in early thymic precursor T-ALLs as well as in a subset (...) of non-ETP T-ALLs. GC-resistant non-ETP T-ALLs are characterized by strong induction of JAK/STAT signaling in response to interleukin-7 stimulation. Removing IL7 or inhibiting JAK/STAT signaling sensitizes these T-ALLs, and a subset of ETP T-ALLs, to GCs. The combination of the GC dexamethasone and the JAK1/2 inhibitor ruxolitinib altered the balance between pro- and anti-apoptotic factors in samples with IL7-dependent GC resistance, but not in samples with IL7-independent GC resistance. Together, these data suggest that the addition of ruxolitinib or other inhibitors of IL7 receptor/JAK/STAT signaling may enhance the efficacy of GCs in a biologically defined subset of T-ALL.Leukemia advance online publication, 30 May 2017; doi:10.1038/leu.2017.136. (shrink)

In this article I begin by discussing the persistent problem of relations between educational inequality and the attainment gap in schools. Because benefits accruing from an education are substantial, the ‘gap’ leads to large disparities in the quality of life many young people can expect to experience in the future. Curriculum knowledge has been a focus for debate in England in relation to educational equality for over 40 years. Given the contestation surrounding views about curriculum knowledge and equality I consider (...) the thinking of two philosophers, Jacques Derrida and Emmanuel Levinas, and their work on justice, to trouble the curriculum framework and discourse of knowledge promoted through the policy text of The Importance of Teaching: The Schools White Paper (2010) and later associated policy reforms to the General Certificate of Secondary Education (GCSE) curriculum in England. The Schools White Paper aims to make the curriculum more challenging to students by introducing tight controls in terms of the assessment framework and curriculum knowledge. I argue that, when considered through Derrida's perspective on language and meaning and Levinas' view on the ethical responsibility for the other, the reforms present obstacles to the search for a just curriculum. I look to the work of Sharon Todd and Paul Standish for a re-imagination of curriculum as or through relations in the light of Derrida's and Levinas' philosophies. (shrink)

Feminist scholars have been remaking the landscape in political theory, and in this important book some of the most important feminist political theorists provide reconstructions of those concepts most central to the tradition of political philosophy. The goal is nothing less than the construction of a blueprint for a positive feminist theory.Many of these papers are completely new; others are extensions of important earlier work; two are reprints of classic papers. The result is a progress report on the continuing feminist (...) project to re-envision traditional political theory. As such, it constitutes essential reading not only for feminist thinkers but also for traditional philosophers and political theorists, who will need to come to terms with these contemporary critiques and re-readings. (shrink)

. Enframing geography: subject, curriculum, knowledge, responsibility. Ethics and Education: Vol. 7, Creating spaces, pp. 277-290. doi: 10.1080/17449642.2013.767004.

Despite rich theoretical development, empirical research on stakeholder management is scant, save its relationship with financial performance. Recent research shows significant intrafirm variability in stakeholder management across time. This study seeks to explain why firms would experience significant changes in stakeholder management. Adapting Wood’s framework to discuss three principles of stakeholder management, the authors identify antecedents of change at the institutional, organizational, and executive levels. Pressures for legitimacy at the institutional level suggest that firm age and size, along with industry (...) shifts in stakeholder management, will increase the likelihood of changes in stakeholder management for the focal firm. The authors posit that organizational risk and performance will also affect the likelihood of change, as will managerial discretion, ownership, and succession. The authors test their predictions using a longitudinal sample of stakeholder management data and discuss the implications of the findings for research and practice. (shrink)

This chapter presents a brief background of curriculum knowledge in England. The idea of ‘relations’ being ‘between’ things pushes one into a ‘this’ and ‘that’ (and maybe ‘and the other’) thinking space. In Jacques Derrida's famous words: ‘Deconstruction is justice’. The responsibility of deconstruction is to disrupt those taken‐for‐granted meanings of curriculum discourses by opening them up and releasing them from their metaphysical assumptions to see what or who may have been overlooked, marginalised and omitted in the process of curriculum‐making. (...) The new model of knowledge formulated in The Schools White Paper for the General Certificate in Secondary Education examinations (GCSE6) is located within a challenging curriculum framework in which grade boundaries are raised, end‐of‐module examinations are replaced with end‐of‐course examinations and opportunities to re‐sit examinations through the course of the programme of study are removed. (shrink)

The subject of geography is declining in popularity at secondary school level and recent developments following the 'cultural turn' in Higher Education have had little impact in revitalising it. In this paper I explore the question: is there a problem with the school geography curriculum policy ? After briefly sketching the history of the Geography National Curriculum policy (GNC), I focus on Caputo's (1997) commentary on Derrida and the idea of deconstruction and invention to explore the contemporary GNC policy text (...) (1999) programme of study at Key Stage 3. (shrink)

This article enquires into the value of 'concepts' as a framework for the school curriculum by questioning their contribution towards our responsibilities for thinking about the earth. I take Derrida's deconstructive reading of Plato's Timaeus to show how spaces in meaning can be revealed, and more transgressive ways of knowing invited in. Derrida's Kh ra marks the opportunity for something new, productive and unforeseeable to arise as the play of traces unfurls. A deconstructive reading of the geography national curriculum policy (...) exposes the impracticality and impossibility of following the text as a definitive scheme and basis for curriculum planning. The paper ends with a spacing of a real place for the geography curriculum by appropriating four different ways of knowing Whitby, a harbour town in north-east England, outside the conceptual scheme. The paper contrasts an approach that is essentially general, conceptual and at the level of the plan, map or net, with a deconstructive approach that welcomes in other, more ethically responsible and imaginative meanings. (shrink)

Research examining consumer responses to the provision of nutritional information as part of restaurant menus has produced mixed results. In light of pending legislation requiring the provision of nutritional information, the authors examine the how corporate social responsibility impacts consumer service evaluation of restaurants. Findings from three studies demonstrate that the relationship between consumer attitudes toward the disclosure of nutrition information and their subsequent evaluation of the food provider is impacted by CSR-related initiatives. Studies one and two find that consumer (...) evaluations are enhanced when the firm has an existing reputation for CSR and when the firm includes healthy product options as part of the introduction of the nutritional information. Study 3 finds these effects are particularly strong with fast-food restaurants. Overall, the findings suggest that, for some firms, the introduction of the legislation provides an opportunity to strengthen relationships with customers and gain advantage over some competitors. (shrink)

Background: Little is known about what factors may contribute to the growth of a consultation service or how a practice may change or evolve across time. Methods: This study examines data collected from a busy ethics consultation service over a period of more than two decades. Results: We report a number of longitudinal findings that represent significant growth in the volume of ethics consultation requests from 19 in 1990 to 551 in 2013, as well as important changes in the patient (...) population for which ethics help is requested. The findings include (1) a steady growth in requests from primary care providers (e.g., physicians and nurses), as well as increases in ancillary services (e.g., social workers); (2) a decrease in length of stay (days) before ethics help is requested; (3) an increase in the reasons that individuals ask for help from ethics; (4) an upsurge in consults requests from areas outside the intensive care unit (ICU); (5) a decrease in patients that died during hospitalization (e.g., live discharges); and (6) growth in the numbers of patients lacking decision-making capacity. Conclusions: We believe the increases in consult requests reflect appropriate and necessary growth because recent consultations have also been associated with consultations requiring (7) additional interventions and (8) reasonably high time intensity scores. (shrink)

Accounts of human beings as essentially social have had a long history in philosophy as reflected in the Ancient Greeks; in African and Asian philosophy; in Modern European thinkers such as Mary Wo...

With the outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), global researchers were confronted with major challenges. The German National Pandemic Cohort Network (NAPKON) was launched in fall 2020 to effectively leverage resources and bundle research activities in the fight against the coronavirus disease 2019 (COVID-19) pandemic. We analyzed the setup phase of NAPKON as an example for multicenter studies in Germany, highlighting challenges and optimization potential in connecting 59 university and nonuniversity study sites. We examined the ethics application (...) process of 121 ethics submissions considering durations, annotations, and outcomes. Study site activation and recruitment processes were investigated and related to the incidence of SARS-CoV-2 infections. For all initial ethics applications, the median time to a positive ethics vote was less than two weeks and 30 of these study sites (65%) joined NAPKON within less than three weeks each. Electronic instead of postal ethics submission (9.5 days (Q1: 5.75, Q3: 17) vs. 14 days (Q1: 11, Q3: 26), p value = 0.01) and adoption of the primary ethics vote significantly accelerated the ethics application process. Each study center enrolled a median of 37 patients during the 14-month observation period, with large differences depending on the health sector. We found a positive correlation between recruitment performance and COVID-19 incidence as well as hospitalization incidence. Our analysis highlighted the challenges and opportunities of the federated system in Germany. Digital ethics application tools, adoption of a primary ethics vote and standardized formal requirements lead to harmonized and thus faster study initiation processes during a pandemic. (shrink)

This report describes a consultation case between a special education teacher and a school psychology student for a first grade student with a diagnosis of educable mental impairment. Adherence to data-based decision making and direct manipulation of hypothesized variables believed to be maintaining problem behaviors in the classroom revealed factors that were influencing the child’s behavior in the classroom. The teacher changed her behavior toward the student before a formal intervention plan could be developed and changes in student behavior were (...) observed. Child outcomes were systematically measured. Also, the acceptability of the consultation process was assessed. Results are discussed in terms of the possible reactive effects to behavioral consultation and functional assessment that may occurfor teachers who see solutions enlerge during data-based consultative problem solving. (shrink)

The allocation of any scarce health care resource, especially a lifesaving resource, can create profound ethical and legal challenges. Liver transplant allocation currently is based upon urgency, a sickest-first approach, and does not utilize capacity to benefit. While urgency can be described reasonably well with the MELD system, benefit encompasses multiple dimensions of patients’ well-being. Currently, the balance between both principles is ill-defined. This survey with 502 participants examines how urgency and benefit are weighted by different stakeholders. Liver transplant patients (...) favored the sickest-first allocation, although all other groups tended to favor benefit. Criteria of a successful transplantation were a minimum survival of at least 1 year and recovery of functional status to being ambulatory and capable of all self-care. An individual delisting decision was accepted when the 1-year survival probability would fall below 50%. Benefit was found to be a critical variable that may also trigger the willingness to donate organs. The strong interest of stakeholder for successful liver transplants is inadequately translated into current allocation rules. (shrink)

Background The allocation of any scarce health care resource, especially a lifesaving resource, can create profound ethical and legal challenges. Liver transplant allocation currently is based upon urgency, a sickest-first approach, and does not utilize capacity to benefit. While urgency can be described reasonably well with the MELD system, benefit encompasses multiple dimensions of patients’ well-being. Currently, the balance between both principles is ill-defined. Methods This survey with 502 participants examines how urgency and benefit are weighted by different stakeholders. Results (...) Liver transplant patients favored the sickest-first allocation, although all other groups tended to favor benefit. Criteria of a successful transplantation were a minimum survival of at least 1 year and recovery of functional status to being ambulatory and capable of all self-care. An individual delisting decision was accepted when the 1-year survival probability would fall below 50%. Benefit was found to be a critical variable that may also trigger the willingness to donate organs. Conclusions The strong interest of stakeholder for successful liver transplants is inadequately translated into current allocation rules. (shrink)

Controversy persists over the ethics of compensating research participants and providing posttrial benefits to communities in developing countries. Little is known about residents' views on these subjects. In this study, interviews about compensation and posttrial benefits from a hypothetical HIV vaccine trial were conducted in Uganda’s Rakai District. Most respondents said researchers owed the community posttrial benefits and research compensation, but opinions differed as to what these should be. Debates about posttrial benefits and compensation rarely include residents' views like these, (...) but future ones should. (shrink)

We discuss here one of our projects, aimed at developing an automatic facial expression interpreter, mainly in terms of signaled emotions. We present some of the relevant findings on facial expressions from cognitive science and psychology that can be understood by and be useful to researchers in Human-Computer Interaction and Artificial Intelligence. We then give an overview of HCI applications involving automated facial expression recognition, we survey some of the latest progresses in this area reached by various approaches in computer (...) vision, and we describe the design of our facial expression recognizer. We also give some background knowledge about our motivation for understanding facial expressions and we propose an architecture for a multimodal intelligent interface capable of recognizing and adapting to computer users¿ affective states. Finally, we discuss current interdisciplinary issues and research questions which will need to be addressed for further progress to be made in the promising area of computational facial expression recognition. (shrink)