With the outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), global researchers were confronted with major challenges. The German National Pandemic Cohort Network (NAPKON) was launched in fall 2020 to effectively leverage resources and bundle research activities in the fight against the coronavirus disease 2019 (COVID-19) pandemic. We analyzed the setup phase of NAPKON as an example for multicenter studies in Germany, highlighting challenges and optimization potential in connecting 59 university and nonuniversity study sites. We examined the ethics application (...) process of 121 ethics submissions considering durations, annotations, and outcomes. Study site activation and recruitment processes were investigated and related to the incidence of SARS-CoV-2 infections. For all initial ethics applications, the median time to a positive ethics vote was less than two weeks and 30 of these study sites (65%) joined NAPKON within less than three weeks each. Electronic instead of postal ethics submission (9.5 days (Q1: 5.75, Q3: 17) vs. 14 days (Q1: 11, Q3: 26), p value = 0.01) and adoption of the primary ethics vote significantly accelerated the ethics application process. Each study center enrolled a median of 37 patients during the 14-month observation period, with large differences depending on the health sector. We found a positive correlation between recruitment performance and COVID-19 incidence as well as hospitalization incidence. Our analysis highlighted the challenges and opportunities of the federated system in Germany. Digital ethics application tools, adoption of a primary ethics vote and standardized formal requirements lead to harmonized and thus faster study initiation processes during a pandemic. (shrink)

A busca pela felicidade está naturalmente presente como um ideal a ser alcançado por cada indivíduo da espécie humana. Kant, em sua obra Fundamentação da Metafísica dos Costumes, pretende buscar e estabelecer o princípio supremo da moralidade e esclarece que para esse fim o ideal da felicidade não apresenta condições de fundamentar as leis da moralidade. Na obra Crítica da Razão Prática, Kant sustenta essa mesma posição, mas introduz o objeto do soberano bem, referente ao qual, a felicidade é o (...) seu segundo elemento, mas condicionada às leis da moralidade e entendida como elemento necessário do soberano bem. O objetivo deste trabalho é realizar uma breve reflexão sobre a importância da felicidade na teoria moral kantiana, enfatizando a relação estabelecida entre a moralidade e a felicidade no conceito do soberano bem. Pretendemos defender que embora o princípio da moralidade e o princípio da felicidade própria fundamentam-se em princípios diferentes, há possibilidades de conciliar a busca da felicidade própria com a realização das ações morais. Palavras-chave: Felicidade. Moralidade. Soberano bem. Imperativo categórico. Imperativo hipotético. (shrink)

Der Verfasser geht von der allgemeinen Unterscheidung zwischen Menschenrechten, Grundrechten und Bürgerrechten aus. Da diese Trennung terminologisch in den relevanten Europäischen Verträgen nicht vorgenommen wird, bemerkt er, dass eine strenge Trennung zwischen Menschen-, Grund- und Bürgerrechten nicht unbedingt notwendig und mitunter auch nicht sinnvoll ist. Daher orientiert er sich an den wichtigsten gemeinsamen Werten bei der gründlichen Analyse und Bewertung der gesetzlichen Normierung der Menschenrechte in der Europäischen Union: im Unionsvertrag, in der Charta der Grundrechte, in anderen Akten sowie in (...) der Praxis der europäischen Institutionen. Der Friede als Grundziel der europäischen Einigung kann vor allem durch die Freiheit und die Beachtung der Grundund Menschenrechte stabilisiert werden. Die wichtigste Grundlage für die Bildung einer gemeinsamen europäischen Identität ist das Sichbesinnen auf die gemeinsamen europäischen Werte und auf die Grund- und Menschenrechte, die den europäischen Kulturraum so besonders prägen und Europa eine Seele geben. (shrink)

The author starts with general differentiation between human, fundamental and civil rights. Considering that such distinction in terms isn’t supported in European conventions, he remarks that strict distinction between human, fundamental and civil rights isn’t unconditionally obligatory, and therefore meaningful. That’s why he focuses on common values through his thorough analysis and evaluation of legal standardization of human rights in the European Union: The treaty on European Union, Charter of fundamental rights, other documents and practises of European institutions. Peace, being (...) the basic aim of European unification, can remain stabile through ,,in the first line”, freedom and respect of fundamental and human rights. The most important foundation for developing common European identity is awareness of common European values and fundamental and human rights, which mark the European cultural space in a particular way and provide Europe with the spirit. (shrink)

L’auteur part de la distinction générale entre les droits de l’homme, les droits fondamentaux et les droits civiques. Etant donné que cette séparation terminologique n’est pas appliquée dans les traités européens, il note qu’une différenciation stricte entre les droits de l’homme, les droits fondamentaux et les droits civiques n’est pas indispensable, ni cohérente. C’est pourquoi il se tourne vers les valeurs communes en analysant et en évaluant la normalisation législative des droits de l’homme dans l’Union européenne : le Traité sur (...) l’Union européenne, la Charte des droits fondamentaux, ainsi que d’autres prescriptions et pratiques des institutions européennes. La paix, qui est le principal objectif de l’unification européenne, peut se maintenir surtout grâce à la liberté et le respect des droits fondamentaux et des droits de l’homme. Le pilier le plus important de la construction d’une identité européenne commune est la prise de conscience des valeurs européennes communes, des droits fondamentaux et des droits de l’homme qui marquent l’espace culturel européen de manière spécifique et qui constituent l’âme de l’Europe. (shrink)

Autor polazi od općeg razlikovanje između ljudskih, temeljnih i građanskih prava. Budući da takvo terminološko odvajanje nije provedeno u europskim ugovorima, primjećuje kako strogo razlučivanje između ljudskih, temeljnih i građanskih prava nije bezuvjetno nužno, a time ni smisleno. Stoga se orijentira na zajedničke vrednote pri temeljitoj analizi i vrednovanju zakonskoga normiranja ljudskih prava u Europskoj Uniji: Ugovora o Europskoj Uniji, Povelje o temeljnim pravima, drugih propisa i prakse europskih institucija. Mir kao osnovni cilj europskoga ujedinjenja može se stabilizirati prije svega (...) pomoću slobode i poštivanja temeljnih i ljudskih prava. Najvažnija je osnova za izgradnju zajedničkoga europskog identiteta osvješćivanje zajedničkih europskih vrednota te temeljnih i ljudskih prava koja europski kulturni prostor obilježuju na poseban način, a Europi daju dušu. (shrink)

Important features of space and time are taken to be missing in quantum gravity, allegedly requiring an explanation of the emergence of spacetime from non-spatio-temporal theories. In this paper, we argue that the explanatory gap between general relativity and non-spatio- temporal quantum gravity theories might significantly be reduced with two moves. First, we point out that spacetime is already partially missing in the context of general relativity when understood from a dynamical perspective. Second, we argue that most approaches to quantum (...) gravity already start with an in-built distinction between structures to which the asymmetry between space and time can be traced back. (shrink)

The first part of the article discusses the conditions under which the “school” of thought known as “philosophical anthropology” arose and the relevance today of the problems it posed, concluding with a look at the recent prevalence taken by biological research. The second part examines the conceptions advanced by its leading figures, Max Scheler, Helmuth Plessner and Arnold Gehlen, and shows how each of them contributed to a “sociologization of anthropological knowledge.” On the basis of this analysis, philosophical anthropology proves (...) itself capable of making a significant contribution to an interdisciplinary understanding of the conditions of human life and to reflection on the foundations of sociological research and social theory. (shrink)

When people are asked to estimate the probabilities of uncertain events, they often neglect the additivity principle, which requires that the probabilities assigned to an exhaustive set of outcomes should add up to 100%. Previous studies indicate that additivity neglect is dependent on response format, self-generated probability estimates being more coherent than estimates on rating scales. The present study made use of eye-tracking methodology, recording the movement, frequency and duration of fixations during the solution of ten additivity problems and two (...) control tasks. Participants produced more non-additive estimates in the Scale format than in the Self-generated format. Self-generated estimates also led to longer decision time and a higher number of repeated inspections, suggesting a deliberate comparison process. In contrast, the Scale format seemed to encourage a case-based approach where each outcome is evaluated in isolation. (shrink)

This volume examines Arnold Gehlen’s theory of the state from his philosophy of the state in the 1920s via his political and cultural anthropology to his impressive critique of the post-war welfare state. The systematic analyses the book contains by leading scholars in the social sciences and the humanities examine the interplay between the theory and history of the state with reference to the broader context of the history of ideas. Students and researchers as well as other readers interested in (...) this subject will find this book offers an informative overview of how one of the most wide-ranging and profound thinkers of the twentieth century understands the state. With contributions by Oliver Agard, Heike Delitz, Joachim Fischer, Andreas Höntsch, Tim Huyeng, Rastko Jovanov, Frank Kannetzky, Christine Magerski, Zeljko Radinkovic, Karl-Siegbert Rehberg and Christian Steuerwald. (shrink)

English summary: The modern age understands justice not only as being an object of jurisprudence. Historical, philosophical, social and cultural studies along with theological approaches each draw near to justice in their own way. This collection devotes itself to the intricate interaction of outside perspectives with the judicial-interdisciplinary thematisation of the law, presenting revised papers delivered at the Protestant Institute for Interdisciplinary Research's symposium in honour of Professor Dr. Dres. h.c. Eberhard Schmidt-Aamann. The case studies and basic considerations deal with, (...) among other things, the function of the law in antique city states, the immanence and transcendence of justice from a theological perspective, as well as the relationship between economics and legal study. German description: Das Recht ist in der Moderne langst nicht nur Gegenstand der Rechtswissenschaft. Historische, philosophische, sozial- und kulturwissenschaftliche wie auch theologische Ansatze nahern sich dem Recht in je eigener Weise. Solche Aussenperspektiven stehen in komplexer Wechselwirkung mit der juristisch-binnendisziplinaren Thematisierung des Rechts. Dieser Sammelband ist dem Wechselspiel von Aussen- und Binnenperspektiven gewidmet. Er vereint die uberarbeiteten Beitrage eines Symposions, das an der Forschungsstatte der Evangelischen Studiengemeinschaft in Heidelberg zu Ehren von Prof. Dr. Dres. h.c. Eberhard Schmidt-Assmann veranstaltet wurde. Die exemplarischen Fallstudien und Grundsatzuberlegungen thematisieren unter anderem die Funktion des Rechts in antiken Stadtstaaten, die Immanenz und Transzendenz des Rechts aus theologischer Perspektive sowie das Verhaltnis von Okonomik und Rechtswissenschaft. Mit Beitragen von: Hans Diefenbacher, Hans-Joachim Gehrke, Klaus Gunther, Christoph Mollers, Thorsten Moos, Michael Moxter, Bernhard Nagel, Martin Ramstedt, Karl-Siegbert Rehberg, Magnus Schlette, Eberhard Schmidt-Assmann. (shrink)