According to a mainstream position in contemporary cognitive science and philosophy, the use of abstract compositional concepts is amongst the most characteristic indicators of meaningful deliberative thought in an organism or agent. In this article, we show how the ability to develop and utilise abstract conceptual structures can be achieved by a particular kind of learning agent. More specifically, we provide and motivate a concrete operational definition of what it means for these agents to be in possession of abstract concepts, (...) before presenting an explicit example of a minimal architecture that supports this capability. We then proceed to demonstrate how the existence of abstract conceptual structures can be operationally useful in the process of employing previously acquired knowledge in the face of new experiences, thereby vindicating the natural conjecture that the cognitive functions of abstraction and generalisation are closely related. (shrink)

In this paper we will discuss constraints on the number of (non-dummy) players and on the distribution of votes such that local monotonicity is satisfied for the Public Good Index. These results are compared to properties which are related to constraints on the redistribution of votes (such as implied by global monotonicity). The discussion shows that monotonicity is not a straightforward criterion of classification for power measures.

Cet article considère les concepts de la confession et de la parrêsia dans l’oeuvre de Michel Foucault et les applique à l’analyse de la construction du sujet femme. Il montre comment dans une perspective confessionnelle, la femme entretiendrait un rapport à ellemême et aux autres qui tend à un auto-assujettissement selon des catégories normatives essentialistes. À ce dire-vrai confessionnel, j’oppose le dire-vrai parrèsiastique, en m’interrogeant sur la possibilité d’attribuer un rôle émancipateur à l’identité « femme ». La parrêsia devient alors (...) le modèle d’un discours critique, qui se rapproche de la critique sociale caractérisant le féminisme. Je retrouve ainsi dans l’histoire du féminisme des témoignages de ce que Foucault redécouvre chez le Grecs comme parrêsia politique, éthique et cynique. (shrink)

Cet article considère les concepts de la confession et de la parrêsia dans l’oeuvre de Michel Foucault et les applique à l’analyse de la construction du sujet femme. Il montre comment dans une perspective confessionnelle, la femme entretiendrait un rapport à ellemême et aux autres qui tend à un auto-assujettissement selon des catégories normatives essentialistes. À ce dire-vrai confessionnel, j’oppose le dire-vrai parrèsiastique, en m’interrogeant sur la possibilité d’attribuer un rôle émancipateur à l’identité « femme ». La parrêsia devient alors (...) le modèle d’un discours critique, qui se rapproche de la critique sociale caractérisant le féminisme. Je retrouve ainsi dans l’histoire du féminisme des témoignages de ce que Foucault redécouvre chez le Grecs comme parrêsia politique, éthique et cynique. (shrink)

Neste texto, o autor persegue dois objetivos: Examinar o de-senvolvimento da doutrina fenomenológica do conteúdo dos estados intencionais representacionais, isto é, dos estados mentais, partindo da concepção brentaniana do conteúdo intencional, examinando a contri-buição de Twardowski pela tripla distinção entre ato, conteúdo e obje-to, e apresentando as críticas que Husserl formulou a propósito dos dois predecessores, na análise do conteúdo intencional das Logische Un-tersuchungen e no contexto da doutrina da intencionalidade como corre-lação noético-noemática; Mostrar como a fenomenologia poderia intervir no (...) debate entre internalismo e externalismo, mediante uma sé-rie de argumentos anti-externalistas, a partir do conteúdo dos estados intencionais. (shrink)

The control of mRNA synthesis in the unicellular eukaryote Saccharomyces cerevisiae involves a number of promoter elements, including an upstream activation site (UAS), an RNA initiation element (RIE) and, for some genes, a form of negative element. The UAS is involved in the activation and regulation of transcription, whilst the RIE, which comprises a transcription initiation site (or I site), and often a TATA box, is responsible for the accurate positioning of the 5′ end of the mRNA. The mechanism whereby (...) these promoter elements interact involves specific protein‐DNA binding events and possibly alterations in chromatin structure. (shrink)

The issue of physician refusal of requested treatment has fueled a two-pronged debate in our society-one on the meaning of futility and the other on the limits of patient autonomy. The latter is a genuinely philosophic dispute; the former, it seems, is a modern relapse into nominalism.It is not the meaning of a word, but the moral basis for the actions of the par-ticipants that should be the focus of our attention, Yet the medical literature distracts us with articles titled (...) “Medical Futility: Its Meaning and Ethical Implica-tions” “The Problem with Futility” “Who Defines Futility?,” “The Illusion of Futility,” and even “Beyond Futility.”The history of the futility debate, which was launched by a 1983 study of Bedell and Delbanco that demonstrated the ineffectiveness of CPR for certain catego-ries of patients, has been documented elsewhere. Here we will inquire if the term, and its rapid intrusion into the medical lexicon, serves a useful purpose or if, as Truog suggested, we would all be better off if this new buzzword were jettisoned. (shrink)

Research involving minors has been the subject of much ethical debate. The growing number of longitudinal, pediatric studies that involve genetic research present even more complex challenges to ensure appropriate protection of children and families as research participants. Long-term studies with a genetic component involve collection, retention and use of biological samples and personal information over many years. Cohort studies may be established to study specific conditions (e.g. autism, asthma) or may have a broad aim to research a range of (...) factors that influence the health and development of children. Studies are increasingly intended to serve as research platforms by providing access to data and biological samples to researchers over many years. (shrink)

In classifications of vocabulary knowledge, vocabulary size and depth have often been separately conceptualized (Schmitt, 2014). Although size and depth are known to be substantially correlated, it is not clear whether they are a single construct or two separate components of vocabulary knowledge (Yanagisawa & Webb, 2020). This issue has not been addressed extensively in the literature and can be better examined using structural equation modeling (SEM), with measurement error modeled separately from the construct of interest. The current study reports (...) on conventional and Bayesian SEM approaches (e.g., Muthén & Asparouhov, 2012) to examine the factor structure of the size and depth of second language vocabulary knowledge of Japanese adult learners of English. A total of 255 participants took five vocabulary tests. One test was designed to measure vocabulary size in terms of the number of words known, while the remaining four were designed to measure vocabulary depth in terms of word association, polysemy, and collocation. All tests used a multiple-choice format. The size test was divided into three subtests according to word frequency. Results from conventional and Bayesian SEM show that a correlated two-factor model of size and depth with three and four indicators, respectively, fit better than a single-factor model of size and depth. In the two-factor model, vocabulary size and depth were strongly correlated (r =.945 for conventional SEM and.943 for Bayesian SEM with cross loadings), but they were distinct. The implications of these findings are discussed. (shrink)

Although most studies on the Fair Trade initiative are, to some extent, cognizant of its contribution to environmental sustainability, what the environmental aspect means to Fair Trade has not yet been explored fully. A review of environmental issues in the Fair Trade literature suggests that Fair Trade might influence participant producers’ farming practices even if it does not directly impact natural resources. This paper attempts to interpret Fair Trade certification as an intermediary institution that links two significant objectives of rural (...) development in the global South—environmental conservation and poverty reduction. This theoretical concept is examined in different real settings by observing four cases of Southern small farmer groups involved in the Fair Trade initiative. Findings from these case studies imply that if Fair Trade certification ensures tangible benefits for small farmers, it can not only help such disadvantaged farmers but also work as an approach for natural resource management. (shrink)

Situationists (e.g., Doris in Lack of character: personality and moral behavior, Cambridge University Press, Cambridge, 2002; Harman in Proc Aristot Soc 99:315–331, 1999. 10.2307/4545312), with reference to empirical work in psychology, have called into question the predictive and explanatory power of character traits and on this basis have criticized the empirical adequacy of moral virtue. More recently, Alfano (Philos Q 62(247):223–249, 2012; Character as moral fiction, Cambridge University Press, Cambridge, 2013) has extended the situationist critique from virtue ethics to virtue (...) epistemology. On the line he advances, virtue responsibilism—the view that intellectual character traits play an important part in traditional and untraditional epistemological inquiries—is criticized as empirically inadequate in light of the extent to which individuals are shown to be susceptible to seemingly trivial and epistemically irrelevant situational influences. Alfano’s attempted redeployment of the situationist challenge to virtue responsibilism is on closer inspection not as straightforward as he claims. It is granted that the empirical adequacy of virtue responsibilism will be eventually threatened if it can be shown that virtuous motivation is, in light of situational factors, causally ineffective. As it turns out, various psychological studies which situationists have overlooked, suggest that virtuous motivation is causally efficacious in a way that favours the position of the virtue responsibilist over the situationist. In the first part of this paper, I outline the hard core of virtue theory: both a rich motivation requirement, and a commitment to the inherent relation between virtue and a good life; then I assess whether these are undermined by situationist criticism. I address the confusion of the existing debate, and the conclusion drawn is that virtue theory ultimately remains unscathed. In the second part of my paper I defend the empirical adequacy of virtue theory based on self-determination theory. When we afford closer attention to studies on the orientation of our motivation, it becomes clear how the dynamics of our motivation have a tremendous influence on desirable behavioural outcomes: a good life. (shrink)

The Grand Chamber of the European Court of Human Rights has recently handed down its judgement in the case of three women contesting the abortion law in the Republic of Ireland, which has one of the most restrictive abortion laws in the world. Although the Court ruled that Ireland had to clarify the current law following the success of one of the three claims, the failure of the other two claims allows Ireland to continue to enforce its law, which has (...) an adverse effect on women's health. This paper, therefore, proposes an amendment to abortion legislation in the Republic of Ireland that would be compatible with safeguarding women's health, highlighting several circumstances in which the continuation of a pregnancy may have a detrimental impact on a woman's physical and/or mental health. (shrink)

This paper offers an account of collective epistemic vices, which we call the “group identification account”. The group identification account attributes collective epistemic vices to the groups that are constituted by “group identification”, which is a primitive and non-doxastic self-understanding as a group member (Turner, 1982; Brewer, 1991; Brewer & Gardner, 1996; Pacherie, 2013; Salice & Miyazono, 2020). The distinctive feature of the group identification account is that it enables us to attribute epistemic vices not just to established social groups (...) (e.g. committees, research teams, juries) but also to loose social groups (e.g. loosely connected people in an echo chamber) when they are constituted by group identification. The group identification account is contrasted with Fricker’s (2010, 2020) influential account, the “joint commitment account”, which focuses on established social groups, and has difficulty in making sense of collective epistemic vices of loose social groups. The group identification account is motivated by the fact that collective epistemic vices can be useful to diagnose not only the epistemic performance of established groups but also that of loose groups in real-life cases, such as echo chamber (Nguyen, 2020), implicit bias (Holroyd, 2020), group polarization (Broncano-Berrocal & Carter, 2021), etc. (shrink)

In his book Bad Beliefs, Neil Levy defends the engineering of our epistemic environment by removing epistemic pollutions and by nudging people through second-order evidence. Although we agree with his core ideas, in this commentary, we aim at supplementing his approach in light of the participation of the general public in science. In the first part, we argue that the issue of participatory epistemic injustice in the scientific community remains unaddressed in Levy’s discussion and that addressing the issue is equal (...) to removing an epistemic pollution. In the second part, we address the issue of transparency in nudging. Here, we discuss the significance of public engagement in controlling the system of nudges to respect our rational and autonomous choices. (shrink)

This paper examines the use and meaning of the body-part terms or quasi-body part terms associated with Japanese emotions. The terms analyzed are kokoro, mune, hara, ki, and mushi. In Japanese kokoro is regarded as the seat of emotions. Mune (roughly, ‘chest’) is the place where Japanese believe kokoro is located. Hara (roughly, ‘belly’) can be used to refer to the seat of ‘thinking’, for example in expression of anger-like feelings which entail a prior cognitive appraisal. The term ki (roughly, (...) ‘breath’) is also used for expressions dealing with emotions, temperament, and behaviour; among these, ki is mostly frequently used for referring to mental activity. Mushi — literally, a ‘worm’ which exists in the hara ‘belly’ — is also used for referring to specific emotion expressions. The tool for semantic analysis employed in this paper is the “Natural Semantic Metalanguage” method developed by Anna Wierzbicka and colleagues. This metalanguage enables us to explicate concepts by means of simple words and grammar (easily translated across languages), and clarifies the similarities and dissimilarities between the components involved in semantically similar terms. The data used for analysis are from various sources; published literature both in Japanese and English, newspaper/magazine articles, film scripts, comic books, advertisements, dictionaries, and popular songs. (shrink)

This paper examines the use and meaning of the body-part terms or quasi-body part terms associated with Japanese emotions. The terms analyzed are kokoro, mune, hara, ki, and mushi. In Japanese kokoro is regarded as the seat of emotions. Mune (roughly, ¿chest¿) is the place where Japanese believe kokoro is located. Hara (roughly, ¿belly¿) can be used to refer to the seat of ¿thinking¿, for example in expression of anger-like feelings which entail a prior cognitive appraisal. The term ki (roughly, (...) ¿breath¿) is also used for expressions dealing with emotions, temperament, and behaviour; among these, ki is mostly frequently used for referring to mental activity. Mushi ¿ literally, a ¿worm¿ which exists in the hara ¿belly¿ ¿ is also used for referring to specific emotion expressions. The tool for semantic analysis employed in this paper is the ¿Natural Semantic Metalanguage¿ method developed by Anna Wierzbicka and colleagues. This metalanguage enables us to explicate concepts by means of simple words and grammar (easily translated across languages), and clarifies the similarities and dissimilarities between the components involved in semantically similar terms. The data used for analysis are from various sources; published literature both in Japanese and English, newspaper/magazine articles, film scripts, comic books, advertisements, dictionaries, and popular songs. (shrink)

En Towards a genealogy of pharmaceutical practice, sostuvimos que la práctica farmacológica daba lugar a un nuevo tipo de biopoder, con tecnologías y racionalidades propias, que lo distinguían del biopoder que había reconocido Michel Foucault en su trabajo tardío. Pero también sostuvimos que su contracara era la generación de nuevas formas de resistencia. En este artículo presentaremos dos modelos específicos de resistencias producidos por el dispositivo del poder farmacológico: uno, que tiene como caso básico el de los movimientos pro-anorexia, que (...) operan resignificando la categoría misma de la patología “anoréxica” en base al fármaco Xenical; otro, que tiene referencia en la experiencia relatada por Beatriz Preciado en su libro Testo yonqui y que actúa superando los límites legales, médicos y morales, para arrojarse a la producción de una nueva identidad jamás antes trazada al consumir dosis no permitidas de testosterona en gel. (shrink)

Factory floors throughout the global economy are rapidly transforming themselves into potentially fertile laboratories for research in the cognitive sciences. The information revolution has challenged our understanding of perception and cognition. Innovations in information technologies have also provided us with new methods and environments for the study of cognition. On the business and economic front, information technology is supporting the development of new corporate information systems-Enterprise Systems-that will revolutionize the decision-making, reporting and reward environments in corporations. These systems are pervasive (...) and transforming. At all levels, employees will be presented with potentially unlimited amounts of accurate, real-time information and will be expected to use that information effectively. The possibilities for research, especially for modeling the learning and decision-making processes, are unparalleled. Research conducted in these environments offers extraordinary opportunities to address research questions formerly requiring limited synthetic environmental situations. Data collected in firms as they deploy enterprise information systems can be more extensive and accurate and more easily quantified than data from traditional synthetic experiments. Research programs in these settings can also address more complex problems of human interaction and collaborativity. This article describes the aspects of enterprise systems that will be of greates interest to cognitive scientists. It also outlines the nature of potential collaboration between economists and cognitive scientists and offers a list of outstanding questions for systems design and development. (shrink)

L'etude historique du principe de vie dans l'oeuvre de Descartes et dans celle de ses predecesseurs souligne notamment l'enjeu de la scission cartesienne entre l'ame et les phenomenes biologiques. Elle permet de comprendre, dans sa nouveaute radicale, la notion de principe de vie chez Descartes, qui associe la decouverte recente de la circulation du sang par W. Harvey, a une explication mecanique de la chaleur du coeur. Du traite de L'Homme aux Passions de l'ame, Descartes identifie en effet la notion (...) de principe de vie a la chaleur contenue dans le coeur, nourrie par la circulation du sang. Une telle conception s'oppose a la vision aristotelicienne, ou la biologie et la psychologie sont etroitement liees, ainsi qu'aux adeptes du panpsychisme que Descartes a critiques: Campanella et Henry More. (shrink)

Recent studies indicate that mammalian chromosomes contain discretecis‐acting loci that control replication timing, mitotic condensation, and stability of entire chromosomes. Disruption of the large non‐coding RNA gene ASAR6 results in late replication, an under‐condensed appearance during mitosis, and structural instability of human chromosome 6. Similarly, disruption of the mouse Xist gene in adult somatic cells results in a late replication and instability phenotype on the X chromosome. ASAR6 shares many characteristics with Xist, including random mono‐allelic expression and asynchronous replication timing. (...) Additional “chromosome engineering” studies indicate that certain chromosome rearrangements affecting many different chromosomes display this abnormal replication and instability phenotype. These observations suggest that all mammalian chromosomes contain “inactivation/stability centers” that control proper replication, condensation, and stability of individual chromosomes. Therefore, mammalian chromosomes contain four types ofcis‐acting elements, origins, telomeres, centromeres, and “inactivation/stability centers”, all functioning to ensure proper replication, condensation, segregation, and stability of individual chromosomes. (shrink)

BackgroundDefensive practice occurs when physicians provide services, such as tests, treatments and referrals, mainly to reduce their perceived legal or reputational risks, rather than to advance patient care. This behaviour is counter to physicians’ ethical responsibilities, yet is widely reported in surveys of doctors in various countries. There is a lack of qualitative research on the drivers of defensive practice, which is needed to inform strategies to prevent this ethically problematic behaviour.MethodsA qualitative interview study investigated the views and experiences of (...) physicians in Australia on defensive practice and its contribution to low value care. Interviewees were recruited based on interest in medico-legal issues or experience in a health service involved in ‘Choosing Wisely’ initiatives. Semi-structured interviews averaged 60 min in length. Data were coded using the Theoretical Domains Framework, which encapsulates theories of behaviour and behaviour change.ResultsAll participants (n = 17) perceived defensive practice as a problem and a contributor to low value care. Behavioural drivers of defensive practice spanned seven domains in the TDF: knowledge, focused on inadequate knowledge of the law and the risks of low value care; skills, emphasising patient communication and clinical decision-making skills; professional role and identity, particularly clinicians’ perception of patient expectations and concern for their professional reputation; beliefs about consequences, especially perceptions of the beneficial and harmful consequences of defensive practice; environmental context and resources, including processes for handling patient complaints; social influences, focused on group norms that encourage or discourage defensive behaviour; and emotions, especially fear of missing a diagnosis. Overall, defensive practice is motivated by physicians’ desire to avoid criticism or scrutiny from a range of sources, and censure from their professional peers can be a more potent driver than perceived legal consequences.ConclusionsThe findings call for strengthening knowledge and skills, for example, to improve clinicians’ understanding of the law and their awareness of the risks of low value care and using effective communication strategies with patients. Importantly, supportive cultures of practice and organisational environments are needed to create conditions in which clinicians feel confident in avoiding defensive practice and other forms of low value care. (shrink)

Ontologies are the prime way of organizing data in the Semantic Web. Often, it is necessary to combine several, independently developed ontologies to obtain a complete representation of a domain of interest. The complementarity of existing ontologies can be leveraged by merging them. Existing approaches for ontology merging mostly implement a binary merge. However, with the growing number and size of relevant ontologies across domains, scalability becomes a central challenge. A multi-ontology merging technique offers a potential solution to this problem. (...) We present Co Merger, a scalable multiple ontologies merging method. It takes as input a set of source ontologies and existing mappings across them and generates a merged ontology. For efficient processing, rather than successively merging complete ontologies pairwise, we group related concepts across ontologies into partitions and merge first within and then across those partitions. In both steps, user-specified subsets of generic merge requirements (GMRs) are taken into account and used to optimize outputs. The experimental results on well-known datasets confirm the feasibility of our approach and demonstrate its superiority over binary strategies. A prototypical implementation is freely accessible through a live web portal. (shrink)

Biobanks, collecting human specimen, medical records, and lifestyle-related data, face the challenge of having contradictory missions: on the one hand serving the collective welfare through easy access for medical research, on the other hand adhering to restrictive privacy expectations of people in order to maintain their willingness to participate in such research. In this article, ethical frameworks stressing the societal value of low-privacy expectations in order to secure biomedical research are discussed. It will turn out that neither utilitarian nor communitarian (...) or classical libertarian ethics frameworks will help to serve both goals. Instead, John Rawls’ differentiation of the “right” and the “good” is presented in order to illustrate the possibility of “serving two masters”: individual interests of privacy, and societal interests of scientific progress and intergenerational justice. In order to illustrate this counterbalancing concept with an example, the five-pillar concept of the German Ethics Council will be briefly discussed. (shrink)

"Cet ouvrage est le fruit d'un seminaire de philosophie des sciences organise au Centre Sevres a Paris pendant l'annee universitaire 1987-1988"--Avant-propos.

A historical investigation of the exclusion of Africa and Asia from modern histories of philosophy.