The old duality that eventually came to produce the mind/body-problem indicates the problem of transcendental subjectivity. The enduring significance of this problem shows itself in a provocation of any paradigm that has become too objectivistic, too naturalistic – even too idealistic in a certain sense – and too forgetful of its own departure from a perspective always presumed. Analytic philosophy bears a tendency towards such a ‘view from nowhere’ which denies a fundamental subjective connection. The rebuttal of this position entails (...) accepting the interrelation between first- and third-person-perspective; we call this the ‘view from somewhere’. Tracing the tension between the subjective and the objective we find this “view” embraced in the phenomenological tradition. At the same time we find the mind/body-problem seemingly dissolved through, among other key concepts, the introduction of the ‘lived body’. We will see, however, that this is no thorough solution; a fundamental mind/world polarity escapes the phenomenological framework and ends up mounting a critical threat to its own stability. A demonstration is attempted of how both the process of objectification and the process of subjectification falls into regressive patterns. This is due to the interplay of the gaze and the source, the ‘from’ and the ‘towards’: Ajin. Later this argumentation calls for a discussion of the pre-reflective sphere of consciousness. Finally we show the alignment between conclusions driven forth in our own dialectic and the ones found in the philosophy of Nāgārjuna. The transcendental interconstitution of subjectivity and objectivity, perspective and world, has a name in emptiness. (shrink)

We advocate an analysis of meaning that departs from the pragmatic slogan that “meaning is use”. However, in order to avoid common missteps, this claim is in dire need of qualification. We argue that linguistic meaning does not originate from language use as such; therefore we cannot base a theory of meaning only on use. It is important not to neglect the fact that language is ultimately reliant on non-linguistic factors. This might seem to oppose the aforementioned slogan, but it (...) will be made clear how this opposition is chimerical. We propose that meaning traces back to the relation between subjectivity and intersubjectivity, which is at the heart of the matter by inducing strong interdependency between intention and interpretation. But to base a full-fledged analysis of meaning in communicative dyads alone is also insufficient. What needs to be further acknowledged is that meaning sharing becomes regulated by the interactions of a community. This we call consensus and it is at play in framing all communicative acts. Hence arises a triadic structure – we call this the meaningsharing network. The main motivation behind this model is to capture that meaning is not “in the head”, nor is it autonomous of the individual members that constitute it. (shrink)

In this paper, we are mainly concerned with coherentism as an approach to ethical dialog in school. We have two different but connected aims with the paper. The first aim is to say something about general philosophical questions relating to coherentism as a theory in metaethics, and especially in relation to value education; the second aim is to explore some possible implications of coherentism as a method in studying the enterprise of discussing ethical issues and questions with children as well (...) as the study of the actual ethical discussion in school. Furthermore, we evaluate the connection between a coherentistic approach to justification and the methodological parts of a Philosophy with Children, or Community of Inquiry, approach to ethics in school. Related to this, we scrutinize what implications this has for evaluating ethical learning within Philosophy with Children, or Community of Inquiry, as well as implications for evaluation of the Philosophy with Children, or Community of Inquiry, approaches as methods for dealing with ethical matters in school. (shrink)

A main issue in Swedish school debate is the question of how to teach the student a common value system based on democracy and western humanism. The debate is rather intense, to say the least. Not only is the premise that there exists one value system that we share a target for critique, but there is also the question of what value education is or could be. There is, as well, quite a body of research on children's moral development, where (...) many take as their departure the work of Kohlberg. However, there has been little or no attention on how the individual learner conceptualizes and makes meaning out of ethical issues. That is, descriptions of processes. In this paper we will present what we take to be urgent questions that need to be investigated against the background of prior research and practical work at Södra teatern in Stockholm, Sweden. For eight years in a row, Södra teatern has had as a main project to lead a practice on the subject of philosophy with children. Several groups of youths in the age of nine to eighteen have regularly met to discuss philosophical thoughts and problems, which in a democratic manner are settled for discussion by the participants. Today this philosophical practice has spread to the north of Sweden. In Backman's final exam within the teacher education she has explored the development of children's (7‐8 years old) ability to argue for different ethical positions, both verbally and in writing and painting. This practice has been inspired by the tradition at Södra teatern, but customized to fit a regular school class in Luleå, with very little experience of philosophical discussion. In the very short period of five weeks Backman has been able to see quite significant changes in the children's ability to argue for their ethical positions. The study was initiated by examining some argumentative abilities of the pupils, for instance the ability of expressing an argument for an ethical position in writing. In the final part of the study, the same ability was examined in very similar circumstances, and the augment of expressed arguments in writing was significant. Another consideration that was raised as a consequence of the study regards the pupil's conceptualizing of ethical issues. In some conversations about the notion of justice it became clear that children interpreted the term very differently. This is not very surprising but important to pay further attention to. As mentioned earlier, there has been very little attention on how individual children conceptualize ethical issues. In this paper we argue that more interest should be put on investigating these issues in more depth, and we will do this by an outlining of a research application. (shrink)

This article is about a coming project concerning a coherentist approach to ethics in school. The project has two main parts; one theoretical and one empirical. The former focuses on philosophical problems and issues concerning coherentism as a metaethical position in general, and particularly when applied to the field of value education, and the latter aims to study some consequences of a coherentist approach to the study of discussing ethical matters with children.Metaethical coherentism is a position in the discussion about (...) justification of moral judgements. According to coherentism, we build some kind of web in which different moral judgements are connected by some justification‐relation or the like. Some judgements might be more central than others, but these can be justified by the more particular and peripheral ones, and vice versa. Coherentism differs from foundationalism, according to which there are some foundational judgements that are not justified by any other judgements. The rest of our judgements are justified if they are justified by this foundation. We wish to study what benefits a coherentist approach might have in the study of ethical discussions in school. In Sweden, the educational system has as one of its main purposes to mediate a "value foundation" based on "Christian ethical tradition and western humanism" to the pupils. Suppose now that you have a foundationalist approach to ethical discussion in schools, as many seem to have had historically, and that some pupil expresses the judgement that some of his classmates have a lower value than him, due to the colour of their skin. This judgement conflicts with the judgement that the colour of ones skin does not have any bearing of ones value, included in the value foundation of the school. According to a foundationalist, we here have a conflict between foundational values, or so we can suppose. In this case, there is nothing obvious to do to resolve this conflict, because the foundational values cannot be justified; it is supposed that we simply realise the correctness of them by our moral intuition, or the like. A coherentist, on the other side, could point to how these two different judgements gain different amount of justification from other judgements, and thereby hopefully find consensus, and hence dissolve the conflict.Coherentism is not theoretically unproblematic, though. One problem is how to understand the justification‐relation. What does it mean that two propositions justify each other? Philosophers have discussed several different proposals. We give a new proposal, based on some of Arne Naess' theories. With regard to methods for ethical discussion in relation to a coherentistic approach, it seems as a "philosophy with children" approach will seem as a natural choice. (shrink)

For researchers who study technology designs, the application and execution of so-called design-oriented research projects are a common way of funding their research. Against this background, we propose a new methodical approach with which VSD can easily be implemented in such projects and which we call “value declaration”. We share our experience with this method which we gained in two design-oriented research projects.

Background:Ethics rounds are one way to support healthcare personnel in handling ethically difficult situations. A previous study in the present project showed that ethics rounds did not result in significant changes in perceptions of how ethical issues were handled, that is, in the ethical climate. However, there was anecdotal evidence that the ethics rounds were viewed as a positive experience and that they stimulated ethical reflection.Aim:The aim of this study was to gain a deeper understanding of how the ethics rounds (...) were experienced and why the intervention in the form of ethics rounds did not succeed in improving the ethical climate for the staff.Research design:An exploratory and descriptive design with a qualitative approach was adopted, using individual interviews.Participants and research context:A total of 11 healthcare personnel, working in two different psychiatry outpatient clinics and with experience of participating in ethics rounds, were interviewed.Ethical considerations:The study was based on informed consent and was approved by one of the Swedish Regional Ethical Review Boards.Findings:The participants were generally positive about the ethics rounds. They had experienced changes by participating in the ethics rounds in the form of being able to see things from different perspectives as well as by gaining insight into ethical issues. However, these changes had not affected daily work.Discussion:A crucial question is whether or not increased reflection ability among the participants is a good enough outcome of ethics rounds and whether this result could have been measured in patient-related outcomes. Ethics rounds might foster cooperation among the staff and this, in turn, could influence patient care.Conclusion:By listening to others during ethics rounds, a person can learn to see things from a new angle. Participation in ethics rounds can also lead to better insight concerning ethical issues. (shrink)

The Ontology for Biomedical Investigations (OBI) is an ontology that provides terms with precisely defined meanings to describe all aspects of how investigations in the biological and medical domains are conducted. OBI re-uses ontologies that provide a representation of biomedical knowledge from the Open Biological and Biomedical Ontologies (OBO) project and adds the ability to describe how this knowledge was derived. We here describe the state of OBI and several applications that are using it, such as adding semantic expressivity to (...) existing databases, building data entry forms, and enabling interoperability between knowledge resources. OBI covers all phases of the investigation process, such as planning, execution and reporting. It represents information and material entities that participate in these processes, as well as roles and functions. Prior to OBI, it was not possible to use a single internally consistent resource that could be applied to multiple types of experiments for these applications. OBI has made this possible by creating terms for entities involved in biological and medical investigations and by importing parts of other biomedical ontologies such as GO, Chemical Entities of Biological Interest (ChEBI) and Phenotype Attribute and Trait Ontology (PATO) without altering their meaning. OBI is being used in a wide range of projects covering genomics, multi-omics, immunology, and catalogs of services. OBI has also spawned other ontologies (Information Artifact Ontology) and methods for importing parts of ontologies (Minimum information to reference an external ontology term (MIREOT)). The OBI project is an open cross-disciplinary collaborative effort, encompassing multiple research communities from around the globe. To date, OBI has created 2366 classes and 40 relations along with textual and formal definitions. The OBI Consortium maintains a web resource providing details on the people, policies, and issues being addressed in association with OBI. (shrink)

Biological ontologies are used to organize, curate, and interpret the vast quantities of data arising from biological experiments. While this works well when using a single ontology, integrating multiple ontologies can be problematic, as they are developed independently, which can lead to incompatibilities. The Open Biological and Biomedical Ontologies Foundry was created to address this by facilitating the development, harmonization, application, and sharing of ontologies, guided by a set of overarching principles. One challenge in reaching these goals was that the (...) OBO principles were not originally encoded in a precise fashion, and interpretation was subjective. Here we show how we have addressed this by formally encoding the OBO principles as operational rules and implementing a suite of automated validation checks and a dashboard for objectively evaluating each ontology’s compliance with each principle. This entailed a substantial effort to curate metadata across all ontologies and to coordinate with individual stakeholders. We have applied these checks across the full OBO suite of ontologies, revealing areas where individual ontologies require changes to conform to our principles. Our work demonstrates how a sizable federated community can be organized and evaluated on objective criteria that help improve overall quality and interoperability, which is vital for the sustenance of the OBO project and towards the overall goals of making data FAIR. Competing Interest StatementThe authors have declared no competing interest. (shrink)

Vaccine research, as well as the development, testing, clinical trials, and commercial uses of vaccines involve complex processes with various biological data that include gene and protein expression, analysis of molecular and cellular interactions, study of tissue and whole body responses, and extensive epidemiological modeling. Although many data resources are available to meet different aspects of vaccine needs, it remains a challenge how we are to standardize vaccine annotation, integrate data about varied vaccine types and resources, and support advanced vaccine (...) data analysis and inference. To address these problems, the community-based Vaccine Ontology (VO) has been developed through collaboration with vaccine researchers and many national and international centers and programs, including the National Center for Biomedical Ontology (NCBO), the Infectious Disease Ontology (IDO) Initiative, and the Ontology for Biomedical Investigations (OBI). VO utilizes the Basic Formal Ontology (BFO) as the top ontology and the Relation Ontology (RO) for definition of term relationships. VO is represented in the Web Ontology Language (OWL) and edited using the Protégé-OWL. Currently VO contains more than 2000 terms and relationships. VO emphasizes on classification of vaccines and vaccine components, vaccine quality and phenotypes, and host immune response to vaccines. These reflect different aspects of vaccine composition and biology and can thus be used to model individual vaccines. More than 200 licensed vaccines and many vaccine candidates in research or clinical trials have been modeled in VO. VO is being used for vaccine literature mining through collaboration with the National Center for Integrative Biomedical Informatics (NCIBI). Multiple VO applications will be presented. (shrink)

To an increasing extent ethical controversies affect and sometimes obstruct public health work and epidemiological research. In order to improve communication between the concerned parties a model for identification and analysis of ethical conflicts in individual-based research has been worked out in co-operation between epidemiologists and moral philosophers. The model has two dimensions. One dimension specifies relevant ethical principles (as beneficence, non-maleficence, autonomy and justice). The other dimension specifies the groups of persons involved in the conflict under consideration (for example: (...) the study-population, individuals who may benefit from the results, the researchers and their personnel, the community at large). The model has been applied to the problem of legitimacy of case-register research and to problems in psychiatric health services research as well as epidemiological research. (shrink)

Distractibility is one of the key features of attention deficit hyperactivity disorder and has been associated with alterations in the neural orienting and alerting networks. Task-irrelevant stimuli are thus expected to have detrimental effects on the performance of patients with ADHD. However, task-irrelevant presentation of novel sounds seems to have the opposite effect and improve subsequent attentional performance particularly in patients with ADHD. Here, we aimed to understand the neural modulations of the attention networks underlying these improvements. Fifty boys participated (...) in a functional magnetic resonance imaging study in which unique or repeatedly presented sounds were placed before a visual flanker task in 2/3 of the trials. We found that presenting any sound improved task performance in all participants, but the underlying neural mechanisms differed for the type of sound. Familiar sounds led to a stronger increase in activity in the left posterior insula in patients with ADHD compared to typically developing peers. Novel sounds led to activations of the fronto-temporoparietal ventral attention network, likewise in ADHD and TD. These changes in signaling by novelty in the right inferior frontal gyrus were directly related to improved response speed showing that neural orienting network activity following novel sounds facilitated subsequent attentional performance. This mechanism of behavioral enhancement by short distractions could potentially be useful for cognitive trainings or homework situations. (shrink)

This essay first outlines a philosophical theory of concepts and then applies it to two areas of relevance to psychiatrists, especially forensic psychiatrists. In the philosophical theory, the respective roles of verbal and non-verbal definitions are illuminated, and the importance of the phenomenon of division of semantic labour is stressed. It is pointed out that vagueness and ambiguity of a term often result when the term is used for several practical purposes at the same time. Such multi-purpose uses of terms (...) may explain both the current problems associated with the Swedish forensic-psychiatric concept of a severe mental disorder and some of the shortcomings of DSM-IV. 2009 Elsevier Ltd. All rights reserved. (shrink)

The 10th International Conference on Biomedical Ontology (ICBO 2019), was held at the Jacobs School of Medicine and Biomedical Sciences of the University at Buffalo, in Buffalo, NY, USA. It was the 10-year anniversary of the ICBO series, and the return of the conference to Buffalo after the first two ICBO conferences were held in Buffalo in 2009 and 2011. ICBO 2019 was well attended, with 115 registered attendees and additional walk-ins from the local academic community. The program included excellent (...) keynote talks by Barry Smith, “International Standard Ontology,” and Bjoern Peters, “Putting principles into practice: OBO ontologies and applications in immunology,” as well as 23 oral presentations, 26 posters, and one software presentation. There were 53 papers and abstracts submitted for peer-review to ICBO 2019. Each submission was reviewed by three members chosen from the Program Committee. Of these submissions, 43 were accepted for this volume: 19 full papers, 23 poster abstracts, and 1 software demonstration extended abstract. We thank our program committee for their thoughtful reviews. There were also three workshops and four tutorials (listed below) held in conjunction with the main ICBO 2019 meeting. (shrink)

Festschrift for prof. Helge Malmgren. -/- Contents: • Kristoffer Ahlström: Two Levels of Epistemic Inquiry; • Jan Almäng: Till frågan om trancendentala argument; • Kent Gustavsson: Perceptionens gåta; • Björn Haglund: Some Notes on Induction; • Ingvar Johansson: Money and Fictions; • Frank Lorentzon: Intuition och kunskap; • Ingmar Persson: Double Effect Troubles; • Filip Radovic: Wittgenstein om tautologier och andra logiska satser; • Claes Strannegård: Anthropomorphic Artificial Intelligence; • Bolof Stridbeck: Den motbjudande slutsatsen & den plågade filosofen; (...) • Christer Svennerlind: Armstrong on Instantiation as Partial Identity; • Anders Tolland: Mr Darcys berättigade stolthet; • Björn Vickhoff: H-speech: the Musical Self - A Phenomenological Approach to Music & Emotion; • Dag Westerståhl: On the Aristotelian Square of Opposition; • Carl-Gustaf Wikstrand: On Pain States & Mental Causation;. (shrink)

How Wittgenstein's theories have been bent, transformed, and expanded in the world outside philosophy. The expression of his eyes remained the same, a cold, piercing sadness. Yet his final words were "Tell them I had a happy life." This poetic book examines the way Ludwig Wittgenstein has influenced artists of the word beyond his own field, thereby touching the subject of how philosophy can be relevant at large. By studying the ways Wittgenstein's theories have been bent, transformed, and expanded, David (...) Rothenberg shows that responses to the reading of philosophy can take many deep, reflective, and different forms. Aphoristically constructed in the style of E. M. Cioran or Edmond Jabès, carefully illustrated with paintings and drawings by Doug Hall, Leif Haglund, and Debra Pughe, The Possibility of Reddish Green situates Wittgenstein in the age of the sound bite and the artistic fragment, promoting the aesthetic of detachment and yet seeking to find a route through the sea of disconnected, jumbled ideas and changes that mark our time. (shrink)

The paper starts with a presentation of the pure happiness theory, i.e. the idea that the quality a person’s life is dependent on one thing only, viz. how happy that person is. To find out whether this type of theory is plausible or not, I examine the standard arguments for and against this theory, including Nozick’s experience machine argument. I then investigate how the theory can be modified in order to avoid the most serious objections. I first examine different types (...) of epistemic modifications of the theory (e.g. the idea that a person’s happiness is more valuable for her if it is based on a correct perception of her own life), and then turn to a number of modifications which all make the value of a person’s happiness depend on whether the evaluative standard on which her happiness is based satisfies certain requirements. In connection with this, I present and defend my own modified version of the happiness theory. (shrink)

It is often stated that the image of the world which our senses present to us contradicts the scientific worldview in important respects. I challenge this position through a number of arguments centered on the nature of perception and of perceived qualities.

It is not unreasonable to think that the dispute between classical and intuitionistic mathematics might be unresolvable or 'faultless', in the sense of there being no objective way to settle it. If so, we would have a pretty case of relativism. In this note I argue, however, that there is in fact not even disagreement in any interesting sense, let alone a faultless one, in spite of appearances and claims to the contrary. A position I call classical pluralism is sketched, (...) intended to provide a coherent methodological stance towards the issue. Some reasons to recommend this stance are given, as well as some speculations as to why not everyone might want to follow the recommendation. (shrink)