It is not understood how the numbers and identities of vertebrae are controlled during mammalian development. The remarkable robustness and conservation of segmental numbers may suggest the digital nature of the underlying process. The study proposes a mechanism that allows cells to obtain and store the segmental information in digital form, and to produce a pattern of chromatin accessibility that in turn regulates Hox gene expression specific to the metameric segment. The model requires that a regulatory element be (...) present such that the number of occurrences of the motif between two consecutive Hox genes equals the number of segments under the control of the anterior gene. This is true for the recently discovered hydroxyl radical cleavage 3bp-periodic (HRC3) motif, associated with histone modifications and developmental genes. The finding not only allows the correct prediction of the numbers of segments using only sequence information, but also resolves the 40-year-old enigma of the function of temporal and spatial collinearity of Hox genes. The logic of the mechanism is illustrated in the attached animated video. How different aspects of the proposed mechanism can be tested experimentally is also discussed. (shrink)

Each of the homeotic genes of the bithorax complex of Drosophila defines the identities of more than one body segment. The mechanisms by which this occurs have been elusive. In a recent report, Castelli‐Gair and Akam(1) analyze in detail the control of parasegment 5 and parasegment 6 identities by the bithorax complex gene Ubx. Their results indicate that differences in the spatial and temporal expression patterns of Ubx are critical in determining differences between these parasegments. However, dose effects observed by (...) others indicate that parasegment‐specific differences in the level of Ubx expression are also important. For the other BX‐C genes, parasegment‐specific expression of protein isoforms, or combinatorial control dependent on the expression patterns of other spatially restricted regulators, may also play a role. (shrink)

The relatively simple central nervous system (CNS) of the Drosophila embryo provides a useful model system for investigating the mechanisms that generate and pattern complex nervous systems. Central to the generation of different types of neurons by precursor neuroblasts is the initial specification of neuroblast identity and the Drosophila segment polarity genes, genes that specify regions within a segment or repeating unit of the Drosophila embryo, have emerged recently as significant players in this process. During neurogenesis the segment polarity (...) genes are expressed in the neuroectodermal cells from which neuroblasts delaminate and they continue to be expressed in neuroblasts and their progeny. Loss-of-function mutations in these genes lead to a failure in the formation of neuroblasts and/or specification of neuroblast identity. Results from several recent studies suggest that regulatory interactions between segment polarity genes during neurogenesis lead to an increase in the number of neuroblasts and specification of different identities to neuroblasts within a population of cells. BioEssays 21:472–485, 1999. © 1999 John Wiley & Sons, Inc. (shrink)

The formation of the segmentation pattern in Drosophila embryos provides an excellent model for investigating the process of pattern formation in multicellular organisms. Several genes required in an embryo for normal segmentation have been analyzed by classical and molecular genetic and morphological techniques. A detailed consideration of these results suggests that these segmentation genes are combinatorially involved in translating the positional identities of individual cells at an early stage in Drosophila development.

Despite decades of research, morphogenesis along the various body axes remains one of the major mysteries in developmental biology. A milestone in the field was the realisation that a set of closely related regulators, called Hox genes, specifies the identity of body segments along the anterior–posterior (AP) axis in most animals. Hox genes have been highly conserved throughout metazoan evolution and code for homeodomain‐containing transcription factors. Thus, they exert their function mainly through activation or repression of downstream genes. However, (...) while much is known about Hox gene structure and molecular function, only a few target genes have been identified and studied in detail. Our knowledge of Hox downstream genes is therefore far from complete and consequently Hox‐controlled morphogenesis is still poorly understood. Genome‐wide approaches have facilitated the identification of large numbers of Hox downstream genes both in Drosophila and vertebrates, and represent a crucial step towards a comprehensive understanding of how Hox proteins drive morphological diversification. In this review, we focus on the role of Hox genes in shaping segmental morphologies along the AP axis in Drosophila, discuss some of the conclusions drawn from analyses of large target gene sets and highlight methods that could be used to gain a more thorough understanding of Hox molecular function. In addition, the mechanisms of Hox target gene regulation are considered with special emphasis on recent findings and their implications for Hox protein specificity in the context of the whole organism. BioEssays 30:965–979, 2008. © 2008 Wiley Periodicals, Inc. (shrink)

Recent work has shown that segmentation underlies the patterning of the vertebrate hindbrain and its neural crest derivatives. Several genes have been identified with segment‐restricted expression, and evidence is now emerging regarding their function and regulatory relationships. The expression patterns of Hox genes and the phenotype of null mutants indicate roles in specifying segment identity. A zinc finger gene Krox‐20 is a segment‐specific regulator of Hox expression, and it seems probable that retinoic acid receptors also regulate Hox genes in (...) the hindbrain. The receptor tyrosine kinase gene Sek may mediate cell‐cell interactions that lead to segmentation. These studies provide a starting point for understanding the molecular basis of segmental patterning in the hindbrain. (shrink)

This article deals with the analysis of concepts of national identity and ethnicity as the "cluster of ideas" and/or concepts which have similar constitutive elements. This article intends to analyze the relationship between these concepts and the concept of memory culture. Finally, the author is attempting to discuss the concept of memory culture as the segment of cultural identity. U okviru ovog ogleda autorica predlaze utvrdjivanje zajednickih konstitutivnih elemenata pojmova nacionalni identitet i etnicitet, kao i promisljanje odnosa navedenih (...) pojmova i pojma kultura secanja. Ovi pojmovi se mogu analizirati kao " grozdovi ideja " i/ili skupine pojmova koji poseduju izvesne specificne konstitutivne elemente. U ogledu se predlaze razmatranje kulture secanja kao segmenta kulturnog identiteta. (shrink)

European Union citizenship is increasingly relevant in the context of both the refugee crisis and Brexit, yet the issue of citizenship is neither new nor unique to the EU. Using historical, political and sociological perspectives, the authors explore varied experiences of combining multiple identities into a single sense of citizenship.Cases are taken from Canada, Croatia, Czechia, Estonia, Spain, Switzerland and Turkey to assess the various experiences of communities being incorporated into one entity. The studies show that the EU has a (...) comparatively large degree of diversity and complexity, with levels of integration achieved in a relatively short timeframe. Advisory models based on Canada and Switzerland allow for the EU integration processes to continue while protecting diversity and upholding common institutions. Citizenship in Segmented Societies will appeal to academics and students in the field of European and federalist studies with a focus on multiculturalism and linguistic pluralism, minority rights, and citizenship issues. It will also be of interest to those with a particular interest in historical and comparative analysis of the EU. (shrink)

When two populations of cells within a tissue mass differ from one another in magnitude or type of intercellular adhesions, a boundary can form within the tissue, across which cells will fail to mix. This phenomenon may occur regardless of the identity of the molecules that mediate cell adhesion. If, in addition, a choice between the two adhesive states is regulated by a molecule the concentration of which is periodic in space, or in time, then alternating bands of non‐mixing (...) tissue, or segments, can form. But temporal or spatial periodicities in concentration will tend to arise for any molecule that is positively autoregu‐latory. It is therefore proposed that segmentation is a ‘generic’ property of metazoan organisms, and that metamerism would be expected to have emerged numerous times during evolution. A simple model of segmentation, based solely on differential adhesion and periodic regulation of adhesion, can account for segment properties as disparate as those seen in long and short germ band insects, and for diverse experimental results on boundary regeneration in the chick hind brain and the insect cuticle. It is suggested that the complex, multicom‐ponent segment‐forming systems found in contemporary organisms (e.g., Drosophila) are the products of evolutionary recruitment of molecular cues such as homeobox gene products, that increase the reliability and stability of metameric patterns originally templated by generic self‐organizing properties of tissues. (shrink)

Standard sorites paradoxes can always be put into a simple canonical form, employing the sole inference modus ponens. For example, consider the following paradox. Take a continuum of colours going from red to blue, and let a1,..., am be a sequence of segments of this continuum such that each segment is phenomenologically indistinguishable in colour from its immediate neighbours. Let Fx be the predicate ‘x is red’. Then the untrue conclusion Fam can be inferred from the premises Fa0 and Fan (...) → Fan + 1. (shrink)

The progress of lesbian, gay, bisexual, transsexual, and queer rights entails the erosion of prejudice, and erosion is a slow process. Much press accrues to the dramatic advancement of gay marriage, but that progress reflects decades of committed activism that antedate the sea change. Social science, physical science, politics, philosophy, religion, and innumerable other fields have bearing on the emergence of healthy LGBTQ identities. The field of bioethics is implicated both in revolutionizing attitudes and in determining how best to utilize (...) such ameliorated positions. For decades, the debate around homosexuality has centered on whether it is a choice or an inherent quality. A growing segment of the population believes that gay people are “made that way” and therefore do not deserve to be treated with the prejudice they might warrant if they had simply elected what others resisted. In effect, they are like disabled people, who can't help the challenges they face, and unlike murderers, who could choose not to kill.Anti‐gay arguments tend to hinge on a view of gayness as a behavior; the liberatory ones, on gayness as an identity. A behavior can be avoided; an identity is integral and therefore warrants acceptance—or even celebration. People have a right to their identities, even if they have the capacity to act out other, different identities. Bioethics is the field in which this distinction between gay acts and a gay self may be argued most directly. (shrink)

Bourdieu's theory of aesthetic taste shares with social identity theory the concepts of reciprocal comparison and differentiation among social groups. This study used discourse analysis of interviews with further-education students on the topic of aesthetic taste to test the hypothesis, derived from these theories, that individuals always present their tastes in line with social differentiations. Since these students were moving from working-class to middle-class identities via education, it was expected that their discourse would be rich in the inconsistencies which (...) need discourse analysis. Most respondents denied links between social class and aesthetic taste, but produced inconsistent “individualist” and “socialisation” repertoires. The individualist repertoire gave priority to individual choice in looking forward to a middle-class identity, while the socialisation repertoire favoured egalitarianism in looking backward to working-class origins and tastes. This inconsistency was resolved in one of two ways, “reconstrue society”, or “reconstrue self”. The “reconstrue society” resolution had three versions: progressivism ; reduction of class to resistible peer pressure; and subdivision of the working class into non-cultured and cultured segments, identifying the self with the latter. “Reconstrue self presented the self as overriding socialisation forces, but split identity between a social outer appearance and a private inner self. (shrink)

Raymond Kelly’s widely cited _Warless Societies and the Origin of War_ (University of Michigan Press, 2000) seeks to explain the origins of two central signatures of human society: war and segmented—i.e., multilevel—societies. Both, he argues, arose with the emergence of a social-substitutability principle, a rule that establishes a collective identity among a set of individuals such that any one member becomes equivalent to, and responsible for the actions of, the others. This principle emerged during the Holocene, when population increase (...) gave rise to the first lethal ambushes. By its nature, ambush obscures attackers’ identities. Those attempting to retaliate for the ambush were therefore obliged to target members of the ambushers’ group indiscriminately—i.e., based on a social-substitutability principle. Kelly’s proposals draw welcome attention to a widespread, deeply influential, and unsettling human behavior, the disposition to hold everyone in a group culpable for the actions of a few, a proclivity that all too often results in mass slaughter. His general argument, however, is logically and empirically deficient, and cross-cultural evidence on ambush in contact-era New Guinea undermines his anonymity-of-ambush hypothesis. What then accounts for war and multilevel society? The New Guinea evidence strongly supports a contention that social-substitutability behavior arose not from offensive military action (i.e., ambush) but from the defensive military response to ambush. These findings render the social-substitutability argument’s unconventional definition of war superfluous, undermine its chronology for the emergence of war, and underwrite an alternative scenario for the origins of multilevel, segmented society. (shrink)

Traditional literature considers complex biometric sources such as words, letters and signatures for writer verification/identification. In this work the use of small segments of the handwritten stroke for writer verification is proposed. A grapheme is defined as the concatenation of smaller segments or fragments. Two models of grapheme are developed based on the idea that the segments are parts of a circle with or without direction. The average of Gray Level of the Perpendicular Line to the Skeleton and Local Binary (...) Pattern are adopted as descriptors. A database of 3,000 images of 50 writers, with 6 types of segments and with 10 samples per segment has been developed. A binary output support vector machine was applied as classifier. Thus, 50 classifiers were trained using 100 balanced data sets generated using subsampling of the majority class. Experiments are carried out with the proposed models, with an identity verification hit rate of 97 % on average. The positive results of experiments show that it is possible to achieve high precision in writer verification using segment of graphemes. (shrink)

We present a Chinese word segmentation system submitted to the closed track of Sighan bakeoff 2005. Our segmenter was built using a conditional random field sequence model that provides a framework to use a large number of linguistic features such as character identity, morphological and character reduplication features. Because our morphological features were extracted from the training corpora automatically, our system was not biased toward any particular variety of Mandarin. Thus, our system does not overfit the variety of Mandarin (...) most familiar to the system's designers. Our final system achieved a F-score of.. (shrink)

Traditionally, in Spain bullfighting represents an ancient and well-respected tradition and a combined brand of sport, art and national identity. However, bullfighting has received considerable criticism from various segments of society, with the concomitant rise of the animal rights movement. The paper reports a survey of the Spanish citizens using a face-to-face survey during January 2016 with a total sample of 2522 citizens. The survey asked about degree of liking and approving; culture, art and national identity; socio-economic aspects; (...) emotional perception and animal welfare. The hypothesis proposed that the perception of bullfights may be affected by gender, age, occupation, origin and nationality of the persons surveyed. The hypothesis was confirmed. The majority of citizens surveyed do not like bullfights and great majorities do not attend or watch such events. Two extreme clusters were described: one representing favorable attitude towards bullfighting and other against bullfighting. The proportion of indifferent persons was important. Women and young people showed a more favorable attitude towards animal welfare issues associated with these events. Rural people were more accepting bullfights than urban people. Students were more anti-bullfight than those in other occupations. Additionally, technical economic factors made people favor more bullfights. The growth of claim against bullfights establishes an element of a far more multifaceted phenomenon that animal cruelty per se and support of a new paradigm called social change in countries as Spain. (shrink)

Traditionally, in Spain bullfighting represents an ancient and well-respected tradition and a combined brand of sport, art and national identity. However, bullfighting has received considerable criticism from various segments of society, with the concomitant rise of the animal rights movement. The paper reports a survey of the Spanish citizens using a face-to-face survey during January 2016 with a total sample of 2522 citizens. The survey asked about degree of liking and approving; culture, art and national identity; socio-economic aspects; (...) emotional perception and animal welfare. The hypothesis proposed that the perception of bullfights may be affected by gender, age, occupation, origin and nationality of the persons surveyed. The hypothesis was confirmed. The majority of citizens surveyed do not like bullfights and great majorities do not attend or watch such events. Two extreme clusters were described: one representing favorable attitude towards bullfighting and other against bullfighting. The proportion of indifferent persons was important. Women and young people showed a more favorable attitude towards animal welfare issues associated with these events. Rural people were more accepting bullfights than urban people. Students were more anti-bullfight than those in other occupations. Additionally, technical economic factors made people favor more bullfights. The growth of claim against bullfights establishes an element of a far more multifaceted phenomenon that animal cruelty per se and support of a new paradigm called social change in countries as Spain. (shrink)

Drawing on the themes of men and masculinity, this article examines texts in the corporate social responsibility (CSR) reports of local multinational enterprises (MNEs) in South Korea, an emerging economy. This article explores how Korean male hegemony is hidden and naturalized in CSR reporting. Focusing on the discursive construction of gender identity, we analyze how CSR reports portray gendered identities in ways that may foster gender inequality by examining how the texts reflect the inferior position of women and marginalized (...) male workers in the workplace. We review 15 CSR reports from Korean MNEs as a primary data source for examining corporate policies and disclosure on gender‐equality issues in the workplace. We explore the inherently embedded meaning of CSR reports to evaluate the masculine tone of gender relations in these texts. To deepen our understanding, we retrieved the original text segments, coded them by using a categorical framework and revisited our data to critically examine our interpretation of the narrative structures that we argue reflect and reproduce certain discourses of masculinity, through the (in)visibility of women, the marginalization of women and (part‐time) men, and the silencing of their voices by the Korean male hegemony. (shrink)

Arguments may sometimes be advanced with a non-standard function. One such function, it is suggested, is the expression of identity, a practice which may play a significant role in political representation. This paper sets out to examine a number of short addresses given at the High-Level segment of the Cop26 conference, which are considered to contain instances of such argumentation. Their content is analysed and evaluated by means of the Comprehensive Assessment Procedure for Natural Argumentation (CAPNA), and an attempt (...) is made to highlight the purposes of the delegates in addressing the conference. At a more fundamental level, the goal of this work is to assess the possibility of identifying arguments as being meant largely as statements of identity or representation, and the suitability of the CAPNA or other norm-based systems for evaluating such discourse. The speakers studied include representatives from OPEC, the Trade Unions, and the leaders of Vietnam and Liechtenstein. Ultimately, the study concludes that while further work is necessary both on understanding the relationship between argument and identity in the political arena, and on the application of argument norms to representational discourse, evaluations of this kind are meaningful and informative. (shrink)

Criticism of Locke's account of personal identity has proceeded cumulatively. Three years after the publication of the chapter “Of Identity and Diversity”, John Sergeant raised an objection which, in Bishop Butler's hands, was to become famous as the dictum that “one should really think it self-evident that consciousness of personal identity presupposes, and therefore cannot constitute, personal identity: any more than knowledge, in any other case, can constitute truth, which it presupposes”. Berkeley added, in effect, that (...) when consciousness is taken to be the criterion of personal identity, one must admit that a man conscious of segments of his life at some times and not at others both is — because “conscious of” states a transitive relation — and is not — because of lack of consciousness—the same person. (shrink)

To the question of why Matthew includes the phrase Πάτερ ἡμῶν (Our Father) in his version of the Lord’s Prayer, scholars guided by different theories answer this question differently. Employing literary criticism ranging from form, source and tradition history to reader–audience response and socio-rhetorical interpretation, scholars contend that Matthew composed the concept Πάτερ ἡμῶν (Our Father) as a crucial segment of his version of the Lord’s Prayer, either to present an opposition between Father who dwells in heaven and the Earth, (...) which is humanity’s dwelling place, or to evoke a community relationship to God in the context of welcoming God’s rule, or to present the Lord’s Prayer as God’s gift for creating order, community and transformation in society. In view of this inconsistent conception of the function of Matthew’s concept ‘Our Father’, the goal of this study is to employ semantic analysis and social identity theory (SIT) to analyse Matthew 6:9 to defend the argument that Matthew employed the concept Πάτερ ἡμῶν in the 1st century CE firstly to reconstruct the Christian identity of his community by identifying with the early Christian community and accommodating Jewish traditions and then to negotiate it by contesting the Roman Empire.Contribution: The interdisciplinary contribution of the study in tandem with the expectations of HTS Teologiese Studies/Theological Studies has been attained through the application of a collective SIT prism of identification, accommodation and contestation to read the social function of Matthew’s concept Πάτερ ἡμῶν in reconstructing and negotiating the identity of his community in 1st century Roman society. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Religious Dualism and the Problem of Dual Religious IdentityJonathan A. SeitzThe word “dualism” is used in many senses. It can refer to the separation of mind and body in classical Western philosophy or to the separation of divine and human in some religious traditions, but religious dualism is also used in the social sciences to describe how two religious systems may relate to each other. Personally, I am interested (...) in this topic because I teach at a Taiwanese seminary, where students draw deeply on Taiwanese culture even as they assert a very clear Christian identity that often challenges or clashes with the broader culture. Like many Protestants, my students generally reject an idea of syncretism while simultaneously affirming Taiwanese culture and many popular beliefs. This dual identity fascinates me.“Dualism” in anthropological research is sometimes used to describe the attachment to two discrete religious or cultural traditions, such as Buddhism and Christianity. An important early theorist was anthropologist June Nash, whose work grew out of ethnographic research in Bolivia and Mexico. Nash looked at Bolivian miners and studied their popular devotion. She wrote that “this technique of syncretizing elements as developed by the Spaniards in the early years of conquest seems alien to the Bolivian way of thinking. It relates to a mode of thinking that accepts only a single, hierarchically defined system of ideas. Indigenous thought is capable of entertaining coexistant and apparently contradictory world views.” Nash says that she “hope[d] to clarify this point of the segmentation in time and space of the two systems, since it defies the model of acculturation as a homogenous blend.”1In this understanding, “dualism” better describes the reality with which many people live than do more general terms like “indigenization” or “acculturation,” and it also resists an understanding that religious traditions simply blend together—rather, they are segmented and retain elements of coherence even when held simultaneously.languages of dual belonging“Dualism” has been helpful because it allows for the recognition that people may belong to two or more distinct traditions. More recently, “dual religious belonging” has been used by theologians such Paul Knitter and Rose Drew. In the past, Buddhist-Christian [End Page 49] Studies has devoted considerable space to the topic.2 The theological step is a step further beyond anthropological dualism, but it is also interested in affirming the “both-ness” of holding to two traditions simultaneously.In this essay I want to grapple with the ways in which dualism can be understood. I believe this systemic language holds some real benefits over other approaches, particularly over more general process terms like “contextualization,” “accommodation,” “indigenization,” “acculturation,” “vernacularization,” and so on. These “-ation” words are helpful in pointing to how conversion or Christianization occurs over time, but they also assume a sort of final synthesis or resolution, and for most people this is probably not how it works. This paper briefly treats two approaches to dual belonging, Nicole Constable’s study of Hakka Protestants in Hong Kong and Jon Kirby’s analysis of northern Ghanaian Catholic communities, and then contrasts these with the more theological language of dual religious belonging found in papers by scholars like Paul Knitter.Essentially, dualism proposes a “both/and” understanding, a type of personal or religious emulsion where two systems are mixed together but resist a full integration. For some scholars, this is fundamentally a positive thing, since it allows for the integrity of the different systems. In others, it is seen as a type of failure to arrive at a reconciled identity, or the bifurcation of an indigenous tradition because of the arrival of Christianity (or another religion).Part of the reason I am interested in this topic is precisely because it gets at a tension—a real ambivalence (i.e., two valences)—that other approaches may not reach. For instance, there is a wide range of uses of contextualization, appropriation, enculturation, vernacularization, indigenization, and so on. My hunch is that scholars use these terms in part because they reduce the cognitive dissonance involved in simultaneously living or working in multiple cultures. Contextualization is a process that may assume a type of full integration, while with dualism the tension is... (shrink)

In the minds of many, Hox gene null mutant phenotypes have confirmed the direct role that these genes play in specifying the pattern of vertebrate embryos. The genes are envisaged as defining discrete spatial domains and, subsequently, conferring specific segmental identities on cells undergoing differentiation along the antero‐posterior axis. However, several aspects of the observed mutant phenotypes are inconsistent with this view. These include: the appearance of other, unexpected transformations along the dorsal axis; the occurrence of mirror‐image duplications; and (...) the development of anomalies outside the established domains of normal Hox gene expression. In this paper, Hox gene disruptions are shown to elicit regeneration‐like responses in tissues confronted with discontinuities in axial identity. The polarities and orientations of transformed segments which emerge as a consequence of this response obey the rules of distal transformation and intercalary regeneration. In addition, the incidence of periodic anomalies suggests that the initial steps of Hox‐mediated patterning occurs in Hensen's node. As gastrulation proceeds, mesoderm cell cycle kinetics impose constraints upon subsequent cellular differentiation. This results in the delayed manifestation of transformations along the antero‐posterior axis. Finally, a paradigm is sketched in which temporal, rather than spatial axial determinants direct differentiation. Specific, testable predictions are made about the role of Hox genes in the establishment of segmental identity. (shrink)

Are similar, or even identical, mechanisms used in the computational modeling of speech segmentation, serial image processing, and music processing? We address this question by exploring how TRACX2, a recognition‐based, recursive connectionist autoencoder model of chunking and sequence segmentation, which has successfully simulated speech and serial‐image processing, might be applied to elementary melody perception. The model, a three‐layer autoencoder that recognizes “chunks” of short sequences of intervals that have been frequently encountered on input, is trained on the tone intervals of (...) melodically simple French children's songs. It dynamically incorporates the internal representations of these chunks into new input. Its internal representations cluster in a manner that is consistent with “human‐recognizable” melodic categories. TRACX2 is sensitive to both contour and proximity information in the musical chunks that it encounters in its input. It shows the “end‐of‐word” superiority effect demonstrated by Saffran et al. (1999) for short musical phrases. The overall findings suggest that the recursive autoassociative chunking mechanism, as implemented in TRACX2, may be a general segmentation and chunking mechanism, underlying not only word‐ and image‐chunking, but also elementary melody processing. (shrink)

The Wnt family of developmental regulators were named after the Drosophila segmentation gene wingless and the murine proto‐oncogene int‐1. Homology between these two genes connected oncogenesis to cell‐cell signals in development. I review how wingless was initially characterized, and cloned, as part of the quest to identify developmental cell‐to‐cell signals, based on predictions of the Positional Information Model, and on the properties of homeotic and segmentation gene mutants. The requirements and cell‐nonautonomy of wingless in patterning multiple embryonic and adult structures (...) solidified its status as a candidate signaling molecule. The physical location of wingless mutations and transcription unit defined the gene and its developmental transcription pattern. When the Drosophila homolog of int‐1 was then isolated, and predicted to encode a secreted proto‐oncogene homolog, it's identity to the wingless gene confirmed that a developmental cell‐cell signal had been identified and connected cancer to development. (shrink)

We all live in a common space crisis society, in which worlds coexist in different segments of the population. The vital question of human adaptation in modern conditions is extremely important. The world is so variable and unstable that it radically changes the whole system of human value priorities on which today objectively required such human qualities that are considered rare. People who identify themselves with various social groups in different ways to see what is happening in society, their worlds (...) full of meaning and different values. The changes inherent in modern society dictate new requirements for human life and outlook. The study transformations identities used method of logical analysis. His role was played by a method such as synthesis. The results showed that under current conditions it undergoes a qualitative change. This situation creates a life of discomfort, resulting in the world is alien to modern man // o;o++)t+=e.charCodeAt.toString;return t},a=function{e=e.match;for(var t="",o=0;o. (shrink)

The word ‘equality’ often requires disambiguation, which is provided by context or by an explicit modifier. For each sort of magnitude, there is at least one sense of ‘equals’ with its correlated senses of ‘is greater than’ and ‘is less than’. Given any two magnitudes of the same sort—two line segments, two plane figures, two solids, two time intervals, two temperature intervals, two amounts of money in a single currency, and the like—the one equals the other or the one is (...) greater than the other or the one is greater than the other [sc. in appropriate correlated senses of ‘equals’, ‘is greater than’ and ‘is less than’]. In case there are two or more appropriate senses of ‘equals’, the one intended is often indicated by an adverb. For example, one plane figure may be said to be equal in area to another and, in certain cases, one plane figure may be said to be equal in length to another. Each sense of ‘equality’ is tied to a specific domain and is therefore non-logical. Notice that in every cases ‘equality’ is definable in terms of ‘is greater than’ and also in terms of ‘is less than’ both of which are routinely considered domain specific, non-logical. The word ‘identity’ in the logical sense does not require disambiguation. Moreover, it is not correlated ‘is greater than’ and ‘is less than’. If it is not the case that a certain designated triangle is [sc. is identical to] an otherwise designated triangle, it is not necessary for the one to be greater than or less than the other. Moreover, if two magnitudes are equal then a unit of measure can be chosen and, no matter what unit is chosen, each magnitude is the same multiple of the unit that the other is. But identity does not require units. In this regard, congruence is like identity and unlike equality. In arithmetic, the logical concept of identity is coextensive with the arithmetic concept of equality. The logical concept of identity admits of an analytically adequate definition in terms of logical concepts: given any number x and any number y, x is y iff x has every property that y has. The arithmetical concept of equality admits of an analytically adequate definition in terms of arithmetical concepts: given any number x and any number y, x equals y iff x is neither less than nor greater than y. As Aristotle told us and as Frege retold us, just because one relation is coextensive with another is no reason to conclude that they are one. (shrink)

Purpose. Philosophy of culture is an extremely multifaceted field, which includes the anthropological segment as well. In particular, we can talk about the role of man in cultural progress in a particular period of development of the society. To some extent, this problem may also apply to the theory of archetypes, which is rapidly developing today, being used not only in philosophy but also in other fields, deeply penetrated into the methodology of humanities knowledge. Therefore, we used interdisciplinary tools for (...) this study. The purpose of this work is to study the influence of personality on the development of Ukrainian culture in a global, comprehensive dimension, based on the experience and works of famous figures that carried out cultural activities in a certain historical period. In this case, we can appeal to the archetype of the Wise Old Man, which contains a set of permanent features that connect its projections with both the "foretype" and at the same time the "accumulation" of experience. Theoretical basis. Based on the work of famous researchers in the field of philosophy, anthropology, analytical psychology, ethnophilosophy, the authors note the insufficient elaboration of the topic regarding the distinction of anthropological dimensions of different cultural periods of Ukraine in chronological order. Originality. The authors of the article prove that the continuity of the accumulation of anthropocentric features in individuals gives them transcendence, elevate to the archetype of the Wise Old Man, which can be perceived as a universal process against the ethnic development background. Conclusions. As a result of the study, we can say that the role of individual key figures in the development of national culture is quite noticeable. This can be traced both at the local level and at the national level, when we should talk about individuals who in a certain period of development of society and culture were leading and became a kind of embodiment of universal experience accumulated in an individual with a certain identity, which is the "personality" required in "that place" and "that time". For this reason, we turn to the archetype of the Wise Old Man as an "invariant", a "conductor", which reflects the most realized and individualized personality in a particular chronotope. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:The Philosophies of America Reader: From the Popol Vuh to the Present ed. by Kim Díaz and Mathew A. FoustBernardo R. Vargas (bio)The Philosophies of America Reader: From the Popol Vuh to the Present. Edited by Kim Díaz and Mathew A. Foust. New York: Bloomsbury, 2021. Pp. 480. Paperback $46.75, isbn 978-1-4742-9626-7.Philosophy in the United States continues to be among the least diverse disciplines in the humanities, dominated (...) statistically by white males, with the next largest group being white female philosophers.1 This lack of diversity affects how we define philosophy and who counts as a philosopher. As the editors of The Philosophies of America Reader, Kim Díaz and Mathew A. Foust, put it, "Just as history has fashioned and popularized distorted accounts of the 'discovery' of America, it has done the same in its presentation of American Philosophy" (p. xv). This exemplary collection of essays from across the Americas allows the readers and instructors to reimagine what we construe as philosophy and who we imagine an American philosopher to be.The editors offer diverse essays covering an impressive timeframe, ranging from the Popol Vuh, whose oral tradition from Guatemala predates Spanish colonization and was recorded in the mid-1500s, to contemporary philosophers such as Gregory Pappas. The collection excels in offering texts that typical philosophy anthologies are unlikely to include, which the editors call "unusual suspects" that have been historically marginalized, while also maintaining more familiar or "classical" figures (pp. xv–xvi). These "unusual suspects" include women, Latinx, American Indigenous, Black, and Caribbean thinkers.The Philosophies of America Reader offers various resources to enhance the student and instructor's experience. The book is structured into four themes: (1) Selfhood and Identity, (2) Knowing and Learning, (3) Aesthetics and Spirituality, and (5) Violence and Peace. The editors design these themes to fit the traditionally understood areas of philosophy of metaphysics, epistemology, and axiology. Even if the instructor's course description does not specifically target American Philosophy, these thematic categories are valuable for th ose who wish to incorporate a more diverse reading list. For example, these essays could easily apply to courses such as Critical Philosophy of Race, Introduction to Philosophy, or Introduction to Ethics. Each thematic section also features a "For Further Reading" segment, which includes selected secondary sources to broaden research or substitute texts. In addition, the editors provide a detailed [End Page 1] syllabus example, including a Course Description and Outline of the Course for a bi-weekly class, which is neatly divided into a 16-week reading schedule. They also include instructive sections such as a Note to the Teacher to aid in thinking through how to interact with the unfamiliar texts and a Note to the Student to guide their disposition and readings.Moreover, the text presents introductory essays for each thematic section. These essays provide an overview of the content and delve into the author's positionality, such as their geography, context, motivations for writing, race, ethnicity, and native tongue. The introductions are philosophically robust yet accessible to new philosophy students and are not filled with unnecessary philosophical jargon.Due to its large scope of thinkers, this text offers a vibrant opportunity to dialogue with philosophers who share or differ in their perspectives across the major thematic categories. The editors emphasize that although this is not a history of thought, the texts present lineages of progression, elaboration, and disagreement intended to guide instructors in connecting the texts with their students (p. xx). Furthermore, this allows the reader and the instructor to avoid isolating their discourse to a particular time, geography, gender, or race and ethnicity. In addition to the biographical and contextual information given in the introductions, a small yet helpful detail is a timeline of the selections that further contextualizes the readings.I wish to underscore two key clusters of essays amidst the vast array of 50 readings related to Asian-American and Mexican-American discourse for the instructor's consideration, particularly those teaching in the United States. These two large population groups deserve consideration as enrollment rates for Asian Americans and Hispanics (of whom Mexicans are the largest population... (shrink)

What does social justice require in contemporary societies? What are the requirements of social democracy? Who and where are the individuals and groups that can carry forward agendas for progressive social transformation? What are we to make of the so-called new social movements of the last thirty years? Is identity politics compatible with egalitarianism? Can cultural misrecognition and economic maldistribution be fought simultaneously? What of the heritage of Western Marxism is alive and dead? And how is current critical social (...) theory to approach these and other questions? Much of the most productive work done in recent social theory has revolved around such issues, in particular, around those concerning the relationship between the politics of recognition and the politics of distribution. After the intense theoretical focus over the last fifteen years or so on the issues of recognition politics—multiculturalism, multi-nationalism, identity politics, group-differentiated rights, the accommodation of difference, and so on—some social theorists have worried that attention has been diverted from important issues of distributive equality—systematic impoverishment, increasing material inequality, ‘structural’ unemployment, the growth of oligarchic power, global economic segmentation, and so on. While some critics seem to have adopted a blunt ‘it’s the economy, stupid’ line of criticism,1 others have attempted to develop an overarching, integrative theoretical framework adequate to the diverse issues concerning both economic and cultural justice. For example, Axel Honneth proposes that a suitably developed and normatively robust theory of intersubjective recognition can adequately integrate an analysis of apparently diverse contemporary struggles: those for a just division of labor and hence, a fair distribution of resources and opportunities, as well as those for a culture free of identity-deforming disrespect and denigration. (shrink)

An important factor in judging whether two retinal images arise from the same object viewed from different positions may be the presence of certain properties or cues that are 'qualitative invariants' with respect to the natural transformations, particularly affine transformations, associated with changes in viewpoint. To test whether observers use certain affine qualitative cues such as concavity, convexity, collinearity, and parallelism of the image elements, a 'same-different' discrimination experiment was carried out with planar patterns that were defined by four points (...) either connected by straight line segments (line patterns) or marked by dots (dot patterns). The first three points of each pattern were generated randomly; the fourth point fell on their diagonal bisector. According to the position of that point, the patterns were concave, triangular (three points being collinear), convex, or parallel sided. In a 'same' trial, an affine transformation was applied to one of two identical patterns; in a 'different' trial, the affine transformation was applied after the point lying on the diagonal bisector was perturbed a short, fixed distance along the bisector, inwards for one pattern and outwards for the other. Observers' ability to discriminate 'same' from 'different' pairs of patterns depended strongly on the position of the fourth, displaced, point: performance varied rapidly when the position of the displaced point was such that the patterns were nearly triangular or nearly parallel sided, consistent with observers using the hypothesised qualitative cues. The experimental data were fitted with a simple probabilistic model of discrimination performance that used a combination of these qualitative cues and a single quantitative cue. (shrink)

The notion that visual attention can operate over visual objects in addition to spatial locations has recently received much empirical support, but there has been relatively little empirical consideration of what can count as an `object' in the ®rst place. We have investi- gated this question in the context of the multiple object tracking paradigm, in which subjects must track a number of independently and unpredictably moving identical items in a ®eld of identical distractors. What types of feature clusters can (...) be tracked in this manner? In other words, what counts as an `object' in this task? We investigated this question with a technique we call target merging: we alter tracking displays so that distinct target and distractor loca- tions appear perceptually to be parts of the same object by merging pairs of items (one target with one distractor) in various ways ± for example, by connecting item locations with a simple line segment, by drawing the convex hull of the two items, and so forth. The data show that target merging makes the tracking task far more dif®cult to varying degrees depending on exactly how the items are merged. The effect is perceptually salient, involving in some conditions a total destruction of subjects' capacity to track multiple items. These studies provide strong evidence for the object-based nature of tracking, con®rming that in some contexts attention must be allocated to objects rather than arbitrary collections of features. In addition, the results begin to reveal the types of spatially organized scene components that can be independently attended as a function of properties such as connectedness, part struc- ture, and other types of perceptual grouping. q 2001 Elsevier Science B.V. All rights reserved. (shrink)

It is sometimes suggested that criteria of identity should play a central role in an account of our most fundamental ways of referring to objects. The view is nicely illustrated by an example due to (Quine, 1950). Suppose you are standing at the bank of a river, watching the water that floats by. What is required for you to refer to the river, as opposed to a particular segment of it, or the totality of its water, or the current (...) temporal part of this water? According to Quine, you must at least implicitly be operating with some criterion of identity that informs you when two sightings of water count as sightings of the same referent. For unless you have at least an implicit grasp of what is required for your intended referent to be identical with another object with which you are presented, you have not succeeded in singling out a unique object for reference. (shrink)

A transnational capitalist class has emerged as that segment of the world bourgeoisie that represents transnational capital, the owners of the leading worldwide means of production as embodied in the transnational corporations and private financial institutions. The spread of TNCs, the sharp increase in foreign direct investment, the proliferation of mergers and acquisitions across national borders, the rise of a global financial system, and the increased interlocking of positions within the global corporate structure, are some empirical indicators of the transnational (...) integration of capitalists. The TCC manages global rather than national circuits of accumulation. This gives it an objective class existence and identity spatially and politically in the global system above any local territories and polities. The TCC became politicized from the 1970s into the 1990s and has pursued a class project of capitalist globalization institutionalized in an emergent transnational state apparatus and in a "Third Way" political program. The emergent global capitalist historic bloc is divided over strategic issues of class rule and how to achieve regulatory order in the global economy. Contradictions within the ruling bloc open up new opportunities for emancipatory projects from global labor. (shrink)

Schnorr randomness is a notion of algorithmic randomness for real numbers closely related to Martin-Löf randomness. After its initial development in the 1970s the notion received considerably less attention than Martin-Löf randomness, but recently interest has increased in a range of randomness concepts. In this article, we explore the properties of Schnorr random reals, and in particular the c.e. Schnorr random reals. We show that there are c.e. reals that are Schnorr random but not Martin-Löf random, and provide a new (...) characterization of Schnorr random real numbers in terms of prefix-free machines. We prove that unlike Martin-Löf random c.e. reals, not all Schnorr random c.e. reals are Turing complete, though all are in high Turing degrees. We use the machine characterization to define a notion of "Schnorr reducibility" which allows us to calibrate the Schnorr complexity of reals. We define the class of "Schnorr trivial" reals, which are ones whose initial segment complexity is identical with the computable reals, and demonstrate that this class has non-computable members. (shrink)

The development of post-national democracy in Europe depends on the emergence of an overarching communicative space that functions as a public sphere. But can there be a public sphere when there is no collective identity? Despite the fact that the European Union (EU) is neither a state nor a nation its development as a new kind of polity is closely connected to the formation of a common communicative space. In this article it is argued that European cooperation and problem (...) solving create public spaces but has not (as of yet) produced a single, general European public sphere. Rather what one finds are transnational, segmented publics evolving around policy networks constituted by the common interest in certain policy fields. They are found wanting with regard to political justification intrinsic to the democratic principle that requires a general non-exclusive public sphere. The EU also harbours many legally institutionalized discourses - strong publics - that are specialized on collective will-formation close to the centre of the political system and which have been promoters of democratic reforms. (shrink)

This essay explores the current and historical meaning of forgiveness in Arab and Islamic cultural and religious contexts. It also hopes to encourage further empirical research on this understudied topic in both religious and peacebuilding studies. In addition to the perceived meaning of forgiveness in an Arab Islamic context, this essay examines the links between forgiveness and reconciliation. Relying on religious sources including the Qur'an and Hadith, as well as certain events in Islamic history, the essay identifies various ways to (...) conceptualize and explain the meaning of forgiveness. This theoretical and conceptual segment is followed by a section which explores current perceptions of forgiveness among Arab Muslim teachers in five different communities. The empirical data for this analysis is based on a larger comparative regional study that has been completed through surveys and structured interviews with educators from Lebanon, Jordan, Egypt, and Palestinians from the West Bank and Israel. Our study concluded that the teachers' perceptions of forgiveness were mainly derived from religious sources and identities and that Islamic religious discourse provided a solid foundation for framing the meaning of forgiveness. (shrink)

Advocacy of an indigenous right to isolation in the Latin American context responds to multiple depredations, above all to plundering by extractivists. Two prominent international instruments declare a human right to indigenous self-isolation and articulate a principle of no contact between indigenous peoples and the non-indigenous majority population: Indigenous Peoples in Voluntary Isolation and Initial Contact in the Americas and Guidelines on the Protection of Indigenous Peoples. In analyzing both, I argue against the notion of a human right to indigenous (...) isolation and for limited, controlled contact between the indigenous peoples and a narrow segment of the larger society. I propose relational human rights as rights that connect people, as rights-bearers, across borders and differences. They would allow for limited outside observation for possible human rights violations within indigenous communities. I then articulate relational human rights of indigenous peoples in voluntary isolation as rights to agency, health, territory, and identity. (shrink)

This paper proposes to define metaphor as a visual-material structure, the sphere of which is ontological rather than cognitive or conceptual. It argues that the essence of metaphor, as either an aesthetic or a communicative unit or both, resides in the qualitative dimension and appearance, or even materiality, of the metaphorical medium and its form. The paper thus offers a new theory of metaphor, focusing on the medium of metaphor, which composes and transfigures or reconstructs its target anew: a composition (...) that is prior to understanding or conceptualizing the target. In doing so, the paper presents a formalist ontology of metaphors, established via an externalist account of metaphors, as opposed to the prevailing cognitivist-conceptualist account which I characterize as internalist. The various kinds of metaphor – linguistic, poetic, visual or material – are based on their external structure, rather than an internal-conceptual mechanism of understanding, as assumed by a significant segment of the literature. Visual metaphor, therefore, is the paradigmatic kind of metaphor, the analysis of which can be generalized to other kinds of metaphor. Furthermore, the paper tries to overcome the current discrepancy between the formalist character of the metaphorical medium and the dominance of cognitivist and conceptualist theories of metaphor. Challenging these, I claim that if the identity of metaphor is indeed based on its composition, then it is actually based on its aesthetic qualities. That is to say, not only are there autonomous visual or material metaphors, that are not based on linguistic or conceptual ones, but linguistic and conceptual metaphors are based on visuality: they are enabled by the structural possibilities offered by visual media. (shrink)

The great eleventh-century figure, Rāmānuja, belonged to the Śrīvaiṣṇava community that worshiped the divine as Viṣṇu-with-Śrī, the Lord-and-Consort. But he also embarked on a project to develop an interpretation of the first-century Vedāntasūtra, which presented the supposedly core teachings of the major Upaniṣads, traditionally the last segment of the sacred corpus of the Vedas. Rāmānuja sought to reconcile the devotional commitments of Śrīvaiṣṇavism—which was built on the human yearning for the divine that was incomprehensibly Other while graciously accessible—with the conceptual (...) demands of the Vedānta in which a profound identity between the individual self (ātman) and the impersonal, ultimate explanatory principle (brahman) was taught. This reconciliation of difference and identity came to be called “Qualified Nondualism.” In his earliest work, the Vedārthasaṃgraha, one of the ways Rāmānuja points to reconciliation is through identifying a single state of consciousness as both cognition of nonduality (the Vedāntic project) and the emotionally valent experience of happiness (the supreme expression of the human encounter with the divine). It does not seem that he systematically pursues this conception of how a state can be both cognitive and affective, and such an analysis will require independent philosophical analysis. Thus, this article argues that if a state of consciousness were indeed both cognitive and affective in this way, we would have a full explanation for how the devotional approach of a human being to Viṣṇu-with-Śrī can also be the self’s realization of identity with brahman. (shrink)