Modern information technologies rely on electronic and optical signals transmitting data, expressions, and other signals around the world. Digital networks account for trillions of dollars worth of worldwide commerce, but the nature of their objects is complicated and has proven to be a challenge for customary and legal modes of ownership for expressions. Intellectual property law governed expressions and inventions for the past couple hundred years, but software and other digital objects, due to their ephemeral and non-physical natures, pose (...) some ontological, ethical, and regulatory challenges discussed in this chapter. (shrink)

Examples of successful linguistic communication give rise to two important insights: (1) it should be understood most fundamentally in terms of the pragmatic success of each individual utterance, and (2) linguistic conventions need to be understood as on a par with the non-linguistic regularities that competent language users rely upon to refer. Syntax and semantics are part of what Barwise and Perry call the context of the utterance, contributing to the pragmatics of the utterance. This full and distributed multichannel context (...) determines meaning if anything does. On the standard account of context, context disambiguates the meaning of language, but it is at least as apt in many situations to say that language disambiguates context. In practice, the two work together, sometimes with more emphasis on one than the other. Reference should be understood in pragmatic terms (it is an act) and, since success is often achieved in non-standard, creative ways, any formalisation of pragmatics can only be partial. The need for such an inventive approach to referring traces back to the need for language to be highly efficient, with expressions underdetermining their interpretation. Next, the shared semantic and syntactic regularities, which might seem to be independent of the context of an utterance, should be understood as also being part of that context. Past usage underdetermines how terms can be used since it allows for multiple projections. Successful reference with novel uses that are disambiguated by context can become the ground for new conventions. (shrink)

Common‐sense intuition suggests that, when people are engaged in informational exchanges, they communicate so as to be reasonably sure that they perform the exchanges faithfully. Over the years, we have found evidence suggesting that this intuition, which is woven into several influential theories of human communication, may be misleading. We first summarize this evidence and discuss its potential limitations. Then, we present a new study that addresses the potential limitations. A confederate instructed participants to “pick up the skask” from a (...) tray containing six objects and move it to a specific location. Since skask is a non‐word invented by us, participants had to ask for clarification to perform the instruction faithfully. In contradiction with the intuition that people pursue faithfulness when engaged in informational exchanges, 29 of the 48 participants we tested performed the instruction without asking for clarification. We identified a possible cause for this behavior, which occurred more frequently when avoiding the clarification was unlikely to result in an overt consequence (an error in the execution of the instruction that could be noticed by the confederate or the experimenter). Other factors such as individual differences and the specific interpersonal dynamics of the experimental settings, if they played a role at all, did it to an extent that is unlikely to be comparable to that of the role played by overt consequences. Considered together, our various assessments of the extent to which people engage in faithful informational exchanges converge on a simple conclusion: Communicating faithfully is a substantially demanding task, and people often fail at it. We discuss the implications of this conclusion and speculate on its relevance for understanding the evolutionary past of human communication. (shrink)

A distinction is made between moral indoctrination and instruction in ethics. It is argued that the legitimate and important field of computer ethics should not be permitted to become mere moral indoctrination. Computer ethics is an academic field in its own right with unique ethical issues that would not have existed if computer technology had not been invented. Several example issues are presented to illustrate this point. The failure to find satisfactory non-computer analogies testifies to the uniqueness of computer (...) ethics. Lack of an effective analogy forces us to discover new moral values, formulate new moral principles, develop new policies, and find new ways to think about the issues presented to us. For all of these reasons, the kind of issues presented deserve to be addressed separately from others that might at first appear similar. At the very least, they have been so transformed by computing technology that their altered form demands special attention. (shrink)

A distinction is made between moral indoctrination and instruction in ethics. It is argued that the legitimate and important field of computer ethics should not be permitted to become mere moral indoctrination. Computer ethics is an academic field in its own right with unique ethical issues that would not have existed if computer technology had not been invented. Several example issues are presented to illustrate this point. The failure to find satisfactory non-computer analogies testifies to the uniqueness of computer (...) ethics. Lack of an effective analogy forces us to discover new moral values, formulate new moral principles, develop new policies, and find new ways to think about the issues presented to us. For all of these reasons, the kind of issues presented deserve to be addressed separately from others that might at first appear similar. At the very least, they have been so transformed by computing technology that their altered form demands special attention. (shrink)

Dans les projets de recherche, ingénieurs et designers partagent la volonté de créer des objets qui non seulement fonctionnent mais ont du sens pour ceux qui les utilisent. Cette interrogation sur le sens s'incarne, entre autres, dans des récits et des mises en scène qui permettent de définir la technologie émergente, de lui donner ses limites et d'en qualifier les potentiels dans une mise en cohérence narrative où les exigences de figuration contribuent directement à l'invention. Nous avons choisi d'observer ce (...) travail de « médiation créative » en relevant, derrière les expressions communes, une diversité formelle qui engage l'objet technique dans des voies spécifiques. (shrink)

It is not uncommon in time travel stories to find that the mechanism by which the time travel is achieved is not invented. A time traveller could journey to his/her own past and give the designs of the time travel machine to his/her earlier self as s/he was given the designs as a younger person. These designs never get thought up by anyone. Such a situation would conflict with the usual conception of the acquisition of knowledge. This situation is (...) called the Temporal Epistemic Anomaly and would arise if knowledge is gained at a time prior to the information in question being transmitted but is not discovered or invented at any time. This article examines the implications of information propagating around a causal chain that is closed in time (which is required to create the Anomaly) and whether this information need have a specific origin point. (shrink)

Most current statistical natural language processing models use only local features so as to permit dynamic programming in inference, but this makes them unable to fully account for the long distance structure that is prevalent in language use. We show how to solve this dilemma with Gibbs sam- pling, a simple Monte Carlo method used to perform approximate inference in factored probabilistic models. By using simulated annealing in place of Viterbi decoding in sequence models such as HMMs, CMMs, and CRFs, (...) it is possible to incorporate non-local structure while preserving tractable inference. We use this technique to augment an existing CRF-based information extraction system with long-distance dependency models, enforcing label consistency and extraction template consistency constraints. This technique results in an error reduction of up to 9% over state-of-the-art systems on two established information extraction tasks. (shrink)

: One of the most compelling problems in science consists in understanding how living systems process information. After all, the way they process information defines their capacities to learning and adaptation. There is an increasing consensus in that living systems are not machines in any sense. Biological hypercomputation is the concept coined that expresses that living beings process information non-algorithmically. This paper aims at proving a positive understanding of “non-algorithmic” processes. Many arguments are brought that support the (...) claim. This foster, it is argued, a brand-new understanding of information processing among living beings. (shrink)

Patents on biotech products have a scope that goes well beyond what is covered by the most widely applied ethical justifications of intellectual property. Neither natural rights theory from Locke, nor public interest theory of IP rights justifies the wide scope of legal protection. The article takes human genes as an example, focusing on the component that is not invented but persists as unaltered gene information even in the synthetically produced complementary DNA, the cDNA. It is argued that (...) patent on cDNA holds this information captive, or illegitimately appropriates it in limiting other researchers and inventors’ opportunity to explore new functions and uses based on this non-invented information. A tighter connection between legal IP protection and the use description stated in the patent claim is suggested. By binding protection to the product’s foreseeable functions and use, instead of the product itself and all future uses of it, legitimacy of biotech product patents is restored. (shrink)

Current evolutionary and cognitive theories of religion posit that supernatural agent concepts emerge from cognitive systems such as theory of mind and social cognition. Some argue that these concepts evolved to maintain social order by minimizing antisocial behavior. If these theories are correct, then people should process information about supernatural agents’ socially strategic knowledge more quickly than non-strategic knowledge. Furthermore, agents’ knowledge of immoral and uncooperative social behaviors should be especially accessible to people. To examine these hypotheses, we measured (...) response-times to questions about the knowledge attributed to four different agents—God, Santa Claus, a fictional surveillance government, and omniscient but non-interfering aliens—that vary in their omniscience, moral concern, ability to punish, and how supernatural they are. As anticipated, participants respond more quickly to questions about agents’ socially strategic knowledge than non-strategic knowledge, but only when agents are able to punish. (shrink)

After employing the mindsponge mechanism and 3D information process of creativity to explain the serendipity process in previous chapters, we realize that it may be helpful to delve into the relations between serendipity and the formulation of new values and information connections through non-linear processes. Thus, this chapter summarizes some preliminary attempts to use non-linear information processes to explain serendipity. We also briefly mention the benefits of information exchange among members of social groups and explain this (...) approach. (shrink)

Depression has been linked with impaired executive control and specific impairments in inhibition of negative material. To date, only a few studies have examined the relationship between depressive symptoms and executive functions in response to emotional information. Using a new paradigm, the Affective Shift Task (AST), the present study examined whether depressive symptoms in general, and rumination specifically, are related to impairments in inhibition and set shifting in response to emotional and non-emotional material. The main finding was that depressive (...) symptoms in general were not related to inhibition. Set-shifting impairments were only observed in moderate to severely depressed individuals. Interestingly, rumination was related to inhibition impairments, specifically when processing negative information, as well as impaired set shifting as reflected in a larger shift cost. These results are discussed in relation to cognitive views on vulnerability for depression. (shrink)

Within the medical, legal and bioethical literature, there has been an increasing concern that the information derived from genetic tests may be used to unfairly discriminate against individuals seeking various kinds of insurance; particularly health and life insurance. Consumer groups, the general public and those with genetic conditions have also expressed these concerns, specifically in the context of life insurance. While it is true that all insurance companies may have an interest in the information obtained from genetic tests, (...) life insurers potentially have a very strong incentive to (want to) use genetic information to rate applicants, as individuals generally purchase their own cover and may want to take out very large policies. This paper critically focuses on genetic information in the context of life insurance. We consider whether genetic information differs in any relevant way from other kinds of non-genetic information required by and disclosed to life insurance companies by potential clients. We will argue that genetic information should not be treated any differently from other types of health information already collected from those wishing to purchase life insurance cover. (shrink)

Any great new theoretical framework has an epistemological and an ontological aspect to its philosophy as well as an axiological one, and one needs to understand all three aspects in order to grasp the deep aspiration and idea of the theoretical framework. Presently, there is a widespread effort to understand C. S. Peirce's (1837–1914) pragmaticistic semeiotics, and to develop it by integrating the results of modern science and evolutionary thinking; first, producing a biosemiotics and, second, by integrating it with the (...) progress in cybernetics, information science, and system theory to create a cybersemiotics. In this paper, we focus on the understanding of the evolution of the universe that Peirce produced as an alternative to the mechanistic view underlying classical physics and try to place man in an evolving universe as a creative, aesthetical agent. It is true that modern non-equilibrium physics has made a modern foundation for a profound physical understanding of the basic evolutionary processes in the universe. But science still has not produced a theory that can explain how the creativity of the universe could produce signification, interpretation, and first-person consciousness. To this end, Peirce's thoughts on agapastic evolution coupled with the aesthetically influence of the growth of ideas and reasonableness on man could make a contribution. (shrink)

This paper asks the question of how we can situate the educational subject in what Luciano Floridi has defined as an ‘informational ontology’. It will suggest that Jacques Derrida and Bernard Stiegler offer paths toward rethinking the educational subject that lend themselves to an informational future, as well as speculating on how, with this knowledge, we can educate to best equip ourselves and others for our increasingly digital world. Jacques Derrida thought the concept of the subject was ‘indispensable’ as a (...) function but did not subscribe to or accept any particular theory of how a subject could be defined or developed because it was always situated in and as a context. Following Derrida, Bernard Stiegler explains in Technics and Time: 1 that ‘the relation binding the “who” and the “what” is invention’. As such, the separation between self and world can be seen as artificial, including if this world is perceived wholly or partly as technological, digital or informational. If this is the case, a responsibility is placed on the educator and their part in ‘inventing’ this distinction for future generations. How this invention of the educational subject is negotiated is therefore one the many philosophical tasks for digital pedagogy. (shrink)

There is a good deal of biomedical research that does not produce scientifically useful data because it fails to recruit a sufficient number of subjects. This fact is typically not disclosed to prospective subjects. In general, the guidance about consent concerns the information required to make intelligent self-interested decisions and ignores some of the information required for intelligent altruistic decisions. Bioethics has worried about the ‘therapeutic misconception’, but has ignored the ‘completion misconception’. This article argues that, other things (...) being equal, prospective subjects should be informed about the possibility of non-completion as part of the standard consent process if it is or should be anticipatable that there is a non-trivial possibility of non-completion and that information is likely to be relevant to a prospective subject's decision to consent. The article then considers several objections to the argument, including the objection that disclosing non-completion information would make recruitment even more difficult. (shrink)

With the purpose to understand better the role of information not only in communication systems, but actually in our environmental reality, this paper presented the model of Universal Triangle of Reality, composed by Matter, Energy and Information, as fundamental constitutive components of this reality. Arguments coming from the field of physics, both at the cosmic and microparticles scale are presented, showing undoubtable conclusions that information is a fundamental component of reality in our material world. At the cosmic (...) level, where the unusual high concentration of mass in the black holes constitutes a special state of matter, suitable for analysis of their special properties, the problem of the conservation principle of information is discussed. At the quantum level, the special unusual characteristics derived from the non-localization principle are also highlighted, together with information-involved problems and solutions. The Universal Triangle of Reality in the living systems reveals the high role of the involved information, both as the informational common organization on the entire evolution scale, and as the info-dynamics processes inside of own structure and resulted from interaction with the environment. The relevant advances in the approaching and understanding of the functionality of the living systems from informational point of view are highlighted, showing the high contribution of information concepts in understanding/solving of various older/recent problems in philosophy, neuroscience/neurology/psychiatry, neuro-physics/neuropsychology/behavior sciences, geriatrics/gerontology, biology and life sciences. Keywords: information-matter-energy, universal triangle of reality in non-living and living systems, informational system of human body and living structures, neurosciences and life sciences. (shrink)

Empirical evidence suggests that some health professionals believe consent procedures for the emerging technology of non-invasive prenatal diagnosis (NIPD) should become less rigorous than those currently used for invasive prenatal testing. In this paper, we consider the importance of informed consent and informed choice procedures for protecting autonomy in those prenatal tests which will give rise to a definitive result. We consider whether there is anything special about NIPD that could sanction a change to consent procedures for prenatal diagnosis or (...) otherwise render informed decision-making less important. We accept the claim that the absence of risk of miscarriage to some extent lessens the gravity of the decision to test compared with invasive methods of testing. However, we also claim that the definitive nature of the information received, and the fact that the information can lead to decisions of great significance, makes NIPD an important choice. This choice should only be made by means of a rigorous and appropriately supported decision-making process (assuming that this is what the pregnant woman wants). We conclude that, on balance, consent procedures for NIPD should mirror those for invasive testing, albeit without the need to emphasise procedure-related risk. (shrink)

Are all three of Marr's levels needed? Should they be kept distinct? We argue for the distinct contributions and methodologies of each level of analysis. It is important to maintain them because they provide three different perspectives required to understand mechanisms, especially information-processing mechanisms. The computational perspective provides an understanding of how a mechanism functions in broader environments that determines the computations it needs to perform. The representation and algorithmic perspective offers an understanding of how information about the (...) environment is encoded within the mechanism and what are the patterns of organization that enable the parts of the mechanism to produce the phenomenon. The implementation perspective yields an understanding of the neural details of the mechanism and how they constrain function and algorithms. Once we adequately characterize the distinct role of each level of analysis, it is fairly straightforward to see how they relate. (shrink)

Ideology and its unsaid: the invention of the word and the invention of the notion As a neologism, the invention of “ideology” is justifiably attributed to the French Idéologues,and to Destutt de Tracy in particular. However by defining the scope of the term as “the science of man”, de Tracy broke with the political metaphysics which was in the process of being formulated in the 1770s and 80s, and which came to dominate the legislative debates between 1789 and 1794. The (...) present article examines the reasons for the marginalisation of de Tracy’s notion at this time. The emphasis is placed on the strategic dimension of the attested usage of the pseudo-concept of ideology in the context of the Directoire, itself a period which was strongly marked ideologically. This approach to the history of concepts enables us to reappraise the question of the invention of ideology and its reception by the young Marx. (shrink)

While the mechanisms of apology, forgiveness and reconciliation receive considerable scru-tiny, little attention has been afforded the non-apology. This counterfeit, confected typically by false substi-tution or mis-direction, adds moral insult to moral wrong. The paper elucidates the normative structural relationship among apologiser, the apologetic disposition, and the apology and defends the view of the non-apology as the pretended willingness to recalibrate the moral positional relationship among apologiser, wronged, and wrong without actually doing so.

Perceptual filling-in for vision is the insertion of visual properties (e.g., color, contour, luminance, or motion) into one’s visual field, when those properties have no corresponding retinal input. This paper introduces and provides preliminary empirical support for filled/non-filled pairs, pairs of images that appear identical, yet differ by amount of filling-in. It is argued that such image pairs are important to the experimental testing of theories of consciousness. We review recent experimental research and conclude that filling-in involves brain activity with (...) relatively high integrated information (Phi) compared to veridical visual perceptions. We then present filled/non-filled pairs as an empirical challenge to the integrated information theory of consciousness, which predicts that phenomenologically identical experiences depend on brain processes with identical Phi. (shrink)

Introduction. Non-institutional humanities, philosophical practice, and informal education are “a family like” phenomena that are outside the social institution of science and education and are adjacent to socio-cultural activities and social work. The purpose of the article is to outline the contours of the informal educational creative industry in the postmodern society, which combines non-institutional humanities, philosophical practice, and informal education. Methods. The author uses the methods of autobiographical reflection, comparative analysis, empirical observation and analysis of the primary sources of (...) non-institutional humanities. Scientific novelty of the research. The transition to nonmaterial work of the postmodern era is the reason for the relevance of the area under study. The growing demand of a contemporary for such issues as the meaning of life, happiness, the growth of the precariat, the ousting of philosophy from formal education constitute a new social reality that determines the novelty of the research in the informal educational creative industry. Results. The author classifies non-institutional humanities according to the spheres of its existence and the strategies of subject genesis presented in the teachings. The concept of dedifferentiation is considered as an explanation of the area under study in postmodernism. The specificity of the philosophical approach in the work of a practicing philosopher is considered. Conclusions. The author connects the prospects of the informal educational creative industry with institutionalization in the way of leisure, entertainment, and other personal services. The author makes conclusions about the differences between formal and informal education, and indicates the risks and opportunities for the development of the informal philosophical sector. (shrink)

Inventing novel knowledge to solve problems is a crucial, creative, mechanism employed by humans, to extend their range of action. In this paper, we present TCL (typicality-based compositional logic): a probabilistic, non monotonic extension of standard Description Logics of typicality, and will show how this framework is able to endow artificial systems of a human-like, commonsense based, concept composition procedure that allows its employment in a number of applications (ranging from computational creativity to goal-based reasoning to recommender systems and affective (...) computing). -/- The framework relies on 3 main ingredients: a non monotonic extension of standard Description Logics (allowing to reason on exceptions to inheritance in standard knowledge bases) a probabilistic extension coming from the field of logic programming (the DISPONTE semantics) a cognitive heuristics known ad HEAD-Modifier determining preference rules for the inheritance mechanisms of the novel concepts to be generated via commonsense rules. -/- We report the obtained results and the lessons learned of this research path in the context of model-based AI applications. -/- . (shrink)

Truth conditions of sentences ascribing non-doxastic propositional attitudes seem to depend on the information structure of the embedded clause. In this paper, we argue that this kind of sensitivity is a semantic phenomenon rather than a pragmatic one. We report four questionnaire studies which explore the impact of the information structure on the truth conditions of non-doxastic attitude ascriptions from different perspectives. The results of the first two studies show that the acceptability of those ascriptions can be affected (...) by some structural modifications of the embedded clause, in particular, when we replace a simple form by an equivalent complex _conjunctional_ form (‘_p_ and _q_’). However, it is possible that different evaluations of such ascriptions have a pragmatic source, namely, the ascriptions with embedded conjunction _imply_ that the agent’s attitude transfers to both conjuncts. In the second pair of studies, we further investigate the nature of this implication which can be classified as ‘Conjunction Elimination’ (CE) in the scope of an attitude verb. The results show that CE-inferences in the context of non-factive non-doxastic attitude ascriptions are not easily cancellable and hence of a semantic rather than pragmatic nature. The results are not conclusive when it comes to the factive non-doxastic attitudes. We conclude our findings by some considerations about a potential source of the observed difference between non-factive and factive attitude verbs and the significance of our general findings to the semantic theory of non-doxastic attitude ascriptions. (shrink)

Some general, programmatic points about informal logic are addressed. The informal approach to argument analysis faces serious foundational problems which have been recognized by its practitioners – but informal logic has yet to come together as a clearly defined discipline. Another problem is the dilemma of the dialectician (Sextus Empiricus): informal logic is either trivial or powerless on its own (field expertise is needed). According to Johnson and Blair the central notion in theory of argument is cogency which replaces soundness. (...) An argument is cogent if and only if (i) its premises are rationally acceptable, (ii) its premises are relevant to its conclusion and (iii) its premises provide sufficient reason to accept the conclusion. I propose to understand cogency as a broader notion that includes deductively valid inferences. The criteria of cogency are simply the basic ideals of scientific methodology which requires a respect for available evidence and “reasonable” inference, an awareness of alternatives and a willingness to modify or reject those beliefs that fail to conform to the evidence. Informal logic in the sense of elementary scientific methodology is concerned with proper reasoning and not with proper dialogue. Informal logic involves non-trivial argumentativeskills and abilities applied to the subject area and accessible to every normally intelligent and educated person. (shrink)

Weak Quantum Theory (WQT) and the Model of Pragmatic Information (MPI) are two psychophysical concepts developed on the basis of quantum physics. The present study contributes to their empirical examination. The issue of the study is whether WQT and MPI can not only explain ‘psi’-phenomena theoretically but also prove to be consistent with the empirical phenomenology of extrasensory perception (ESP). From the main statements of both models, 33 deductions for psychic readings are derived. Psychic readings are defined as settings, (...) in which psychics support or counsel clients by using information not mediated through the five senses. A qualitative approach is chosen to explore how the psychics experience extrasensory perceptions. Eight psychics are interviewed with a half-structured method. The reports are examined regarding deductive and inductive aspects, using a multi-level structured content analysis. The vast majority of deductions is clearly confirmed by the reports. Even though the study has to be seen as an explorative attempt with many aspects to be specified, WQT and MPI prove to be coherent and helpful concepts to explain ESP in psychic readings. (shrink)

(1997). Actio non est reactio: An extension of the concept of causality towards phenomena of information. World Futures: Vol. 49, The Quest for a Unified Theory of Information, pp. 409-427.

This systematic review identifies and critically evaluates instruments that have been developed to measure clinical trial informed consent comprehension in non-cognitively-impaired adults.Literature searches were carried out on Medline (Ovid), PsycInfo, CINHAL, ERIC, ScienceDirect, and Cochrane Library for English language articles published between January 1980 and September 2008. Instruments were excluded if they focused on consent onto paediatric trials, the construct under study was primarily capacity or competency, or the instrument was developed specifically for psychiatric or cognitively-impaired populations. Instruments selected for (...) review were evaluated against the following criteria: (1) method of item generation; (2) type and format of test items; (3) administration and interpretation of test results; and (4) psychometric properties.Three instruments met our defined inclusion criteria: the Deaconess Informed Consent Comprehension Test (DICCT), the Quality of Informed Consent (QuIC) questionnaire and the Brief Informed Consent Protocol (BICEP). Each instrument varied in terms of content measured. Significantly, these are the first standardized instruments developed to assess comprehension in non-cognitively-impaired adults. Yet, each instrument had its own set of limitations such as the lack of generalizability and the absence of details pertaining to how test results should be used to guide clinical decision-making.Standardized clinical trial informed consent comprehension assessments have been developed to identify gaps in research participants' understanding and ensure that respect for patient autonomy is satisfied. (shrink)

In this paper, it is argued that Ferguson’s (2003, Argumentation 17, 335–346) recent proposal to reconcile monotonic logic with defeasibility has three counterintuitive consequences. First, the conclusions that can be derived from his new rule of inference are vacuous, a point that as already made against default logics when there are conflicting defaults. Second, his proposal requires a procedural “hack” to the break the symmetry between the disjuncts of the tautological conclusions to which his proposal leads. Third, Ferguson’s proposal amounts (...) to arguing that all everyday inferences are sound by definition. It is concluded that the informal logic response to defeasibility, that an account of the context in which inferences are sound or unsound is required, still stands. It is also observed that another possible response is given by Bayesian probability theory (Oaksford and Chater, in press, Bayesian Rationality: The Probabilistic Approach to Human Reasoning, Oxford University Press, Oxford, UK; Hahn and Oaksford, in press, Synthese). (shrink)

Parents influence the development of their offspring in many ways beyond the transmission of DNA. This includes transfer of epigenetic states, nutrients, antibodies and hormones, and behavioural interactions after birth. While the evolutionary consequences of such nongenetic inheritance are increasingly well understood, less is known about how inheritance mechanisms evolve. Here, we present a simple but versatile model to explore the adaptive evolution of non-genetic inheritance. Our model is based on a switch mechanism that produces alternative phenotypes in response to (...) different inputs, including genes and non-genetic factors transmitted from parents and the environment experienced during development. This framework shows how genetic and non-genetic inheritance mechanisms and environmental conditions can act as cues by carrying correlational information about future selective conditions. Differential use of these cues is manifested as different degrees of genetic, parental or environmental morph determination. We use this framework to evaluate the conditions favouring non-genetic inheritance, as opposed to genetic determination of phenotype or within-generation plasticity, by applying it to two putative examples of adaptive non-genetic inheritance: maternal effects on seed germination in plants and transgenerational phase shift in desert locusts. Our simulation models show how the adaptive value of non-genetic inheritance depends on its mechanism, the pace of environmental change, and life history characteristics. (shrink)

The problem of non-compliance with treatment and its repercussions on the clinical evolution of different conditions has been widely investigated.1–4 Non-compliance has also been shown to have significant economic implications, not only as a result of product loss but also indirectly through the complication of disease management and its subsequent healthcare and social costs.5–7Non-compliance as a health problemThe term “non-compliance” might be taken to refer both to the failure to follow a drug regimen and to the failure to adopt other (...) measures that contribute to improvement in health—for example, changes in lifestyle or diet. This letter focuses on the former.Non-compliance with a drug regimen can be the result of a number of different factors9–11 and a variety of techniques have been developed in an attempt to control it.12,13 Of these, the few techniques that have been shown to be effective have only managed to solve the problem in specific situations over short periods of time. The use of such techniques to control non-compliance, particularly where these are effective, raises interesting ethical questions about the extent to which their application constitutes an infringement of the patient’s right to decide on how to manage their own health.8 Here we suggest that in some cases one factor that leads to non-compliance is the tendency to provide extensive and exhaustive information on side effects in …. (shrink)

The American Journal of Bioethics, Volume 11, Issue 11, Page 22-23, November 2011.

Background: how mind functions is subject to continuing scientific discussion. A simplistic approach says that, since no convincing way has been found to model subjective experience, mind cannot exist. A second holds that, since mind cannot be described by classical physics, it must be described by quantum physics. Another perspective concerns mind's hypothesized ability to interact with the world of quanta: it should be responsible for reduction of quantum wave packets; physics producing 'Objective Reduction' is postulated to form the basis (...) for mind-matter interactions. This presentation describes results derived from a new approach to these problems. It is based on well-established biology involving physics not previously applied to the fields of mind, or consciousness studies, that of critical feedback instability. -/- Methods: 'self-organized criticality' in complexity biology places system loci of control at critical instabilities, physical properties of which, including information properties, are presented. Their elucidation shows that they can model hitherto unexplained properties of experience. -/- Results: All results depend on physical properties of critical instabilities. First, at least one feed-back or feed-forward loop must have feedback gain, g = 1: information flows round the loop impress perfect images of system states back on themselves: they represent processes of perfect self-observation. This annihilates system quanta: system excitations are instability fluctuations, which cannot be quantized. Major results follow: -/- 1. Information vectors representing criticality states must include at least one attached information loop denoting self-observation. -/- 2. Such loop structures are attributed a function, 'registering the state's own existence', explaining -/- a. Subjective 'awareness of one's own presence' -/- b. How content-free states of awareness can be remembered (Jon Shear) -/- c. Subjective experience of time duration (Immanuel Kant) -/- d. The 'witness' property of experience – often mentioned by athletes 'in the zone' -/- e. The natural association between consciousness and intelligence -/- This novel, physically and biologically sound approach seems to satisfactorily model subjectivity. -/- Further significant results follow: -/- 1. Registration of external information in excited states of systems at criticality reduces external wave-packets: the new model exhibits 'Objective Reduction' of wave packets. -/- 2. High internal coherence (postulated by Domash & Penrose) leading to a. Non-separable information vector bundles. b. Non-reductive states (Chalmers's criterion for experience). -/- 3. Information that is: a. encoded in coherence negentropy; b. non-digitizable, and therefore c. computationally without digital equivalent (posited by Penrose). -/- Discussion and Conclusions: instability physics implies anharmonic motion, preventing excitation quantization, and totally different from the quantum physics of simple harmonic motion at stability. Instability excitations are different from anything hitherto conceived in information science. They can model aspects of mind never previously treated, including genuine subjectivity, objective reduction of wave-packets, and inter alia all properties given above. (shrink)

Recently, in an ongoing debate about informal provability, non-deterministic logics of informal provability BAT and CABAT were developed to model the notion. CABAT logic is defined as an extension of BAT logics and itself does not have independent and decent semantics. The aim of the paper is to show that, semantically speaking, both logics are rather complex and they can be characterized by neither finitely many valued deterministic semantics nor possible word semantics including neighbourhood semantics.

This paper highlights the renewed interest in Lucas’s explanation of the non-neutrality of money put forward in his 1972 article – explanation based on information dispersion and signal extraction...

Historians and sociologists of science usually discuss multiple independent inventions or multiple independent discoveries in terms of priority disputes among the inventors. But what should we make of the multiple invention of a technology that not only gave rise to very few priority disputes, but never worked and was rejected by each inventor’s contemporaries as soon as it was made public? This paper examines seven such situations in the history of botany. I devote particular attention to the inventors’ cultural and (...) educational backgrounds, in particular, the scholastic education most of them shared, through which they would have become familiar with Llullian combinatorics and the mnemonic names used to distinguish syllogistic moods. I also examine their conceptions of the roles of nomenclature in botany, their assumptions about how memory works, their awareness of other similar efforts, and their contemporaries’ reactions to their proposals. Finally, I reflect on the impacts that a consideration of multiple independent inventions of failed technologies may have on current approaches to the history and sociology of science. (shrink)

The paper argues that two distinct and independent notions of plurality are involved in natural language anaphora and quantification: plural reference (the usual non-atomic individuals) and plural discourse reference, i.e., reference to a quantificational dependency between sets of objects (e.g., atomic/non-atomic individuals) that is established and subsequently elaborated upon in discourse. Following van den Berg (PhD dissertation, University of Amsterdam, 1996), plural discourse reference is modeled as plural information states (i.e., as sets of variable assignments) in a new dynamic (...) system couched in classical type logic that extends Compositional DRT (Muskens, Linguistics and Philosophy, 19, 143-186, 1996). Given the underlying type logic, compositionality at sub-clausal level follows automatically and standard techniques from Montague semantics become available. The idea that plural info states are semantically necessary (in addition to non-atomic individuals) is motivated by relative-clause donkey sentences with multiple instances of singular donkey anaphora that have mixed (weak and strong) readings. At the same time, allowing for non-atomic individuals in addition to plural info states enables us to capture the intuitive parallels between singular and plural (donkey) anaphora, while deriving the incompatibility between singular (donkey) anaphora and collective predicates. The system also accounts for empirically unrelated phenomena, e.g., the uniqueness effects associated with singular (donkey) anaphora discussed in Kadmon (Linguistics and Philosophy, 13, 273-324, 1990) and Heim (Linguistics and Philosophy, 13, 131-177, 1990) among others. (shrink)