Results for 'negligible senescence'

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  1. Immortality.Gabriel Andrade - 2011 - In James Fieser & Bradley Dowden (eds.), Internet Encyclopedia of Philosophy.
    Immortality is the indefinite continuation of a person’s existence, even after death. In common parlance, immortality is virtually indistinguishable from afterlife, but philosophically speaking, they are not identical. Afterlife is the continuation of existence after death, regardless of whether or not that continuation is indefinite. Immortality implies a never-ending existence, regardless of whether or not the body dies (as a matter of fact, some hypothetical medical technologies offer the prospect of a bodily immortality, but not an afterlife). Immortality has been (...)
     
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  2. Ethical perspectives on advances in biogerontology.Jean Woo, David Archard, Derrick Au, Sara Bergstresser, Alexandre Erler, Timothy Kwok, John Newman, Raymond Tong & Tom Walker - 2019 - Aging Medicine 2 (2):99-103.
    Worldwide populations are aging with economic development as a result of public health initiatives and advances in therapeutic discoveries. Since 1850, life expectancy has advanced by 1 year for every four. Accompanying this change is the rapid development of anti‐aging science. There are three schools of thought in the field of aging science. One perspective is the life course approach, which considers that aging is a good and natural process to be embraced as a necessary and positive aspect of life, (...)
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  3.  8
    The machine-like repair of aging. Disentangling the key assumptions of the SENS agenda.Pablo García-Barranquero & Marta Bertolaso - 2022 - Theoria: Revista de Teoría, Historia y Fundamentos de la Ciencia 37 (3):379-394.
    The possibility of curing aging is currently generating hopes and concerns among entrepreneurs, experts, and the general public. This article aims to clarify some of the key assumptions of the Strategies for Engineered Negligible Senescence agenda, one of the most prominent paradigms for rejuvenation. To do this, we present the three fundamental claims of this research program: (1) aging can be repaired; (2) rejuvenation is possible through the reversal of all molecular damage; (3) and the human organism is (...)
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  4.  12
    The longevity bottleneck hypothesis: Could dinosaurs have shaped ageing in present‐day mammals?João Pedro de Magalhães - 2024 - Bioessays 46 (1):2300098.
    The evolution and biodiversity of ageing have long fascinated scientists and the public alike. While mammals, including long‐lived species such as humans, show a marked ageing process, some species of reptiles and amphibians exhibit very slow and even the absence of ageing phenotypes. How can reptiles and other vertebrates age slower than mammals? Herein, I propose that evolving during the rule of the dinosaurs left a lasting legacy in mammals. For over 100 million years when dinosaurs were the dominant predators, (...)
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  5. Minding Negligence.Craig K. Agule - 2022 - Criminal Law and Philosophy 16 (2):231-251.
    The counterfactual mental state of negligent criminal activity invites skepticism from those who see mental states as essential to responsibility. Here, I offer a revision of the mental state of criminal negligence, one where the mental state at issue is actual and not merely counterfactual. This revision dissolves the worry raised by the skeptic and helps to explain negligence’s comparatively reduced culpability.
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  6. Negligence: its moral significance.Santiago Amaya - 2022 - In Manuel Vargas & John Doris (eds.), The Oxford Handbook of Moral Psychology. Oxford, U.K.: Oxford University Press.
    This is a draft of my chapter on Negligence for the forthcoming Oxford Handbook in Moral Psychology. It discusses philosophical, psychological, and legal approaches to the attribution of culpability in cases of negligent wrongdoing.
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  7. Negligent Action and Unwitting Omissions.Randolph Clarke - 2015 - In Alfred Mele (ed.), Surrounding Free Will. New York, NY, USA: pp. 298-317.
    Negligence and omission are closely related: commonly, in cases of negligent action, the agent has failed to turn her attention to some pertinent fact. But that omission is itself typically unwitting. A sufficient condition for blameworthiness for an unwitting omission is offered, as is an account of blameworthiness for negligent action. It is argued that one can be blameworthy for wrongdoing done from ignorance even if one is not blameworthy for that ignorance.
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  8.  39
    Senescence, Growth, and Gerontology in the United States.Hyung Wook Park - 2013 - Journal of the History of Biology 46 (4):631-667.
    This paper discusses how growth and aging became interrelated phenomena with the creation of gerontology in the United States. I first show that the relation of growth to senescence, which had hardly attracted scientific attention before the twentieth century, started to be investigated by several experimental scientists around the 1900s. Subsequently, research on the connection between the two phenomena entered a new domain through the birth of gerontology as a scientific field comprised of various disciplines, many of which addressed (...)
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  9.  18
    Human senescence.Thomas B. L. Kirkwood - 1996 - Bioessays 18 (12):1009-1016.
    Human life expectancy has increased dramatically through improvements in public health, housing, nutrition and general living standards. Lifespan is now limited chiefly by intrinsic senescence and its associated frailty and diseases. Understanding the biological basis of the ageing process is a major scientific challenge that will require integration of molecular, cellular, genetic and physiological approaches. This article reviews progress that has been made to date, particularly with regard to the genetic contribution to senescence and longevity, and assesses the (...)
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  10. Negligence and self-trust.Samuel Murray - forthcoming - Oxford Studies in Agency and Responsibility.
    Why are we accountable for negligent wrongdoing? This paper develops a contractualist account of accountability for negligent wrongdoing rooted in maintaining self-trust. Displays of negligence threaten the self-trust needed to exercise planning agency. People thus have reason to take responsibility for being negligent to defeat higher-order evidence about the unreliability of one’s planning agency. Individuals are rationally required to take responsibility for negligence in virtue of the demands of planning agency. One novel implication of this view is that taking responsibility (...)
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  11. Senescence and Rejuvenescence.Charles Manning Child - 1917 - Mind 26 (101):104-108.
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  12. Negligence, Belief, Blame and Criminal Liability: The Special Case of Forgetting.Douglas Husak - 2011 - Criminal Law and Philosophy 5 (2):199-218.
    Commentators seemingly agree about what negligence is—and how it is contrasted from recklessness. They also appear to concur about whether particular examples (both real and hypothetical) portray negligence. I am less confident about each of these matters. I explore the distinction between recklessness and negligence by examining a type of case that has generated a good deal of critical discussion: those in which a defendant forgets that he has created a substantial and unjustifiable risk of harm. Even in this limited (...)
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  13.  69
    Negligence.Kenneth W. Simons - 1999 - Social Philosophy and Policy 16 (2):52.
    Negligence is both an important concept and an ambiguous one. Here I concentrate upon the sense of creating an unjustifiable, low-probability risk of future harm. This essay attempts to dispel theprevalent view that only a maximizing, utilitarian approach can render intelligible certain features of negligence analysis—its focus on the marginal advantages and disadvantages of the actor's taking a specific precaution, its consideration and balancing of the short-term effects of different actions, and its sensitivity to a multiplicity of factors. Perhaps certain (...)
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  14. Contributory Negligence: Conceptual and Normative Issues.Kenneth W. Simons - 1995 - In David G. Owen (ed.), Philosophical Foundations of Tort Law. Oxford University Press.
    When a plaintiff has been negligent in the sense that he should have acted otherwise, should the same criterion of negligence apply that would apply if he were creating risks only to others? Indeed, are there any persuasive reasons not to apply a radically different criterion of negligence? Moreover, should the plaintiff's recovery be diminished, outside the category of assumption of risk, even when the plaintiff has not been negligent? What are the justifiable criteria and limits of such plaintiff strict (...)
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  15.  23
    Negligence and Ignorance.A. D. Woozley - 1978 - Philosophy 53 (205):293 - 306.
    The purpose of this paper is to discuss and to relate to each other two topics: the admissibility of ignorance and mistake of fact as defences against negligence in crime; and the inadmissibility of ignorance and mistake of law as defences against criminal charges. I am in not concerned at all with torts negligence, only with criminal offences which can be committed negligently, where negligence suffices for liability, as in the law of homicide. This produces an untidy classification of elements, (...)
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  16.  16
    Agency, Negligence and Responsibility.George Pavlakos & Veronica Rodriguez-Blanco (eds.) - 2021 - New York, NY, USA: Cambridge University Press.
    This collection of essays represents a ground-breaking collaboration between moral philosophers, action theorists, lawyers and legal theorists to set a fresh research agenda on agency and responsibility in negligence. The complex phenomenon of responsibility in negligence is analysed from multi- and interdisciplinary perspectives, shedding light on key ethical and legal issues related to agency and negligence to impact substantive law and policy-making in different jurisdictions. The volume introduces new debates and questions old assumptions, inviting the reader to rethink substantive law (...)
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  17.  17
    Agency, Negligence and Responsibility.George I. Pavlakos & Veronica Rodriguez-Blanco (eds.) - 2021 - New York, NY, USA: Cambridge University Press.
    This collection of essays represents a ground-breaking collaboration between moral philosophers, action theorists, lawyers and legal theorists to set a fresh research agenda on agency and responsibility in negligence. The complex phenomenon of responsibility in negligence is analysed from multi- and interdisciplinary perspectives, shedding light on key ethical and legal issues related to agency and negligence to impact substantive law and policy-making in different jurisdictions. The volume introduces new debates and questions old assumptions, inviting the reader to rethink substantive law (...)
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  18. Negligence, Mens Rea, and What We Want the Element of Mens Rea to Provide.Marcia Baron - 2020 - Criminal Law and Philosophy 14 (1):69-89.
    It is widely agreed that the top three Model Penal Code culpability levels suffice for criminal liability, but the fourth is controversial. And it isn’t just the particular MPC wording; that negligence should be on the list at all is controversial. My question is: What makes negligence so different? What is it about negligence that gives rise to the view that it should not suffice for criminal liability? In addressing it, I draw attention to how we conduct the debate, and (...)
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  19.  8
    Senescence.G. Stanley Hall - 1922 - Journal of Philosophy 19 (19):525-528.
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  20.  18
    Rearranging senescence: Transposable elements become active in aging cells ( C omment on DOI 10.1002/bies.201300097).William M. Keyes - 2013 - Bioessays 35 (12):1023-1023.
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  21. Senescence and youth in stylistics-evaluating late-20th-century stylistics.Jm Klinkenberg - 1993 - Revue Belge de Philologie Et D’Histoire 71 (3):555-571.
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  22.  26
    Tort negligence, cost-benefit analysis and tradeoffs: A closer look at the controversy.Kenneth W. Simons - 2008 - Loyola of Los Angeles Law Review 41 (4):1171-1224.
    What is the proper role of cost-benefit analysis in understanding the tort concept of negligence or reasonable care? A straightforward question, you might think. But it is a question that manages to elicit groans of exasperation from those on both sides of the controversy. For most utilitarians and adherents to law and economics, the answer is obvious: to say that people should not be negligent is to say that they should minimize the sum of the costs of accidents and the (...)
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  23. Senescence.M. Tatar - 2001 - In C. W. Fox D. A. Roff (ed.), Evolutionary Ecology: Concepts and Case Studies. pp. 128--141.
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  24.  12
    Gross negligence manslaughter of intern doctors – scapegoating or justified?Wing Hin Kason Lin - forthcoming - Clinical Ethics.
    Criminalizing unintentional mistakes in medicine as the offence of gross negligence manslaughter has always been a contentious issue. The threshold of prosecution is not well-defined, and even less clear when faced with a situation in which an intern doctor is held liable. This commentary attempts to review the current legal position of holding an intern doctor liable for gross negligence medical manslaughter.
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  25.  49
    Gross negligence manslaughter and doctors: ethical concerns following the case of Dr Bawa-Garba.Ash Samanta & Jo Samanta - 2019 - Journal of Medical Ethics 45 (1):10-14.
    Dr Bawa-Garba, a senior paediatric trainee who had been involved in the care of a child who died shortly after admission to hospital, was convicted of gross negligence manslaughter and subsequently erased from the medical register. We argue that criminalisation of doctors in this way is fraught with ethical tensions at levels of individual blameworthiness, systemic failures, professionalism, patient safety and at the interface of the regulator and doctor. The current response to alleged manslaughter during clinical care is not fit (...)
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  26.  28
    Medical Negligence Determinations, the “Right to Try,” and Expanded Access to Innovative Treatments.Denise Meyerson - 2017 - Journal of Bioethical Inquiry 14 (3):385-400.
    This article considers the issue of expanded access to innovative treatments in the context of recent legislative initiatives in the United Kingdom and the United States. In the United Kingdom, the supporters of legislative change argued that the common law principles governing medical negligence are a barrier to innovation. In an attempt to remove this perceived impediment, two bills proposed that innovating doctors sued for negligence should be able to rely in their defence on the fact that their decision to (...)
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  27.  21
    The initiation of senescence and its relationship to embryonic cell differentiation.Robert F. Rosenberger - 1995 - Bioessays 17 (3):257-260.
    Mouse embryonic stem cells have an unlimited lifespan in cultures if they are prevented from differentiating. After differentiating, they produce cells which divide only a limited number of times. These changes seen in cultures parallel events that occur in the developing embryo, where immortal embryonic cells differentiate and produce mortal somatic ones. The data strongly suggest that differentiation initiates senescence, but this view entails additional assumptions in order to explain how the highly differentiated sexual gametes manage to remain potentially (...)
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  28. Negligent Algorithmic Discrimination.Andrés Páez - 2021 - Law and Contemporary Problems 84 (3):19-33.
    The use of machine learning algorithms has become ubiquitous in hiring decisions. Recent studies have shown that many of these algorithms generate unlawful discriminatory effects in every step of the process. The training phase of the machine learning models used in these decisions has been identified as the main source of bias. For a long time, discrimination cases have been analyzed under the banner of disparate treatment and disparate impact, but these concepts have been shown to be ineffective in the (...)
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  29.  41
    Domesticity, senescence, and suicide.Richard Dawkins - 1980 - Behavioral and Brain Sciences 3 (2):274-275.
  30. Author’s Reply: Negligence and Normative Import.Katrina L. Sifferd & Tyler K. Fagan - 2022 - Criminal Law and Philosophy 16 (2):353-371.
    In this paper we attempt to reply to the thoughtful comments made on our book, Responsible Brains, by a stellar group of scholars. Our reply focuses on two topics discussed in the commenting papers: first, the issue of responsibility for negligent behavior; and second, the broad claim that facts about brain function are normatively inert. In response to worries that our theory lacks normative implications, we will concentrate on an area where our theory has clear relevance to law and legal (...)
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  31. Negligence and moral responsibility.Michael J. Zimmerman - 1986 - Noûs 20 (2):199-218.
  32. The Problem with Negligence.Matt King - 2009 - Social Theory and Practice 35 (4):577-595.
    Ordinary morality judges agents blameworthy for negligently produced harms. In this paper I offer two main reasons for thinking that explaining just how negligent agents are responsible for the harms they produce is more problematic than one might think. First, I show that negligent conduct is characterized by the lack of conscious control over the harm, which conflicts with the ordinary view that responsibility for something requires at least some conscious control over it. Second, I argue that negligence is relevantly (...)
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  33.  26
    Negligence in the Air.Michael S. Moore & Heidi M. Hurd - 2002 - Theoretical Inquiries in Law 3 (2).
    The article examines what has come to be known as "the risk analysis" in Anglo-American tort law and contract law. The risk analysis essentially consists of: viewing negligence as a relational concept, so that a defendant is never simply negligent tout cour, but is negligent only with respect to certain persons and certain harms — other harms suffered by other persons are said not to be "within the risk" that makes the defendant negligent; and the supplanting of proximate cause doctrine (...)
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  34.  67
    Pure Negligence.Steven Sverdlik - 1993 - American Philosophical Quarterly 30 (2):137 - 149.
  35.  18
    Chalcenteric Negligence.S. West - 1970 - Classical Quarterly 20 (02):288-.
    Didymus, in modern works of reference, gets rather a good press. It is conceded on all sides that he was not an original researcher and that his remarks often betray a certain want of common sense. But the general estimate is favourable: more recent works do not substantially dissent from Sandys’ verdict : ‘The age of creative and original scholars was past and the best service that remained to be rendered was the careful preservation of the varied stores of ancient (...)
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  36.  15
    Sacrificial Experts? Science, Senescence and Saving the British Nuclear Project.Jon Agar - 2013 - History of Science 51 (1):63-84.
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  37.  31
    Cellular lifespan and senescence: a complex balance between multiple cellular pathways.David Dolivo, Sarah Hernandez & Tanja Dominko - 2016 - Bioessays 38 (S1):33-44.
    The study of cellular senescence and proliferative lifespan is becoming increasingly important because of the promises of autologous cell therapy, the need for model systems for tissue disease and the implication of senescent cell phenotypes in organismal disease states such as sarcopenia, diabetes and various cancers, among others. Here, we explain the concepts of proliferative cellular lifespan and cellular senescence, and we present factors that have been shown to mediate cellular lifespan positively or negatively. We review much recent (...)
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  38.  10
    “Reproductive Negligence”: A Necessary and Sufficient Remedy?Rachel L. Zacharias - 2020 - Hastings Center Report 50 (5):44-45.
    This book review essay discusses Birth Rights and Wrongs: How Medicine and Technology Are Remaking Reproduction and the Law (2019), by Dov Fox.
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  39. Medical negligence and loss of a chance.C. Stewart - 2009 - Journal of Bioethical Inquiry 6 (1):3-7.
     
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  40.  6
    Chalcenteric Negligence.S. West - 1970 - Classical Quarterly 20 (2):288-296.
    Didymus, in modern works of reference, gets rather a good press. It is conceded on all sides that he was not an original researcher and that his remarks often betray a certain want of common sense. But the general estimate is favourable: more recent works do not substantially dissent from Sandys’ verdict : ‘The age of creative and original scholars was past and the best service that remained to be rendered was the careful preservation of the varied stores of ancient (...)
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  41. Negligence.Kenneth W. Simons - 1999 - Social Philosophy and Policy 16 (2):52-93.
    Faced with the choice between creating a risk of harm and taking a precaution against that risk, should I take the precaution? Does the proper analysis of this trade-off require a maximizing, utilitarian approach? If not, how does one properly analyze the trade-off?These questions are important, for we often are uncertain about the effects of our actions. Accordingly, we often must consider whether our actions create an unreasonable risk of injury — that is, whether our actions are negligent.
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  42.  26
    Negligence and Ignorance.A. D. Woozley - 1978 - Philosophy 53 (205):293-306.
    The purpose of this paper is to discuss and to relate to each other two topics: the admissibility of ignorance and mistake of fact as defences against negligence in crime; and the inadmissibility of ignorance and mistake of law as defences against criminal charges. I am in not concerned at all with torts negligence, only with criminal offences which can be committed negligently, where negligence suffices for liability, as in the law of homicide. This produces an untidy classification of elements, (...)
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  43.  12
    Negligible Motion Artifacts in Scalp Electroencephalography (EEG) During Treadmill Walking.Kevin Nathan & Jose L. Contreras-Vidal - 2015 - Frontiers in Human Neuroscience 9.
  44.  80
    When is Negligent Inadvertence Culpable?: Introduction to Symposium, Negligence in Criminal Law and Morality.Kenneth W. Simons - 2011 - Criminal Law and Philosophy 5 (2):97-114.
    Doug Husak suggests that sometimes an actor should be deemed reckless, and not merely negligent, with respect to the risks that she knowingly created but has forgotten at the moment of action. The validity of this conclusion, he points out, depends crucially on what it means to be aware of a risk. Husak’s neutral prompt and counterfactual actual belief criteria are problematic, however. More persuasive is his suggestion that we understand belief, in this moral and criminal law context, as a (...)
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  45. Negligent investigation : tort law as police ombudsman.Erika Chamberlain - 2009 - In Andrew Robertson & Hang Wu Tang (eds.), The goals of private law. Portland, Or.: Hart.
     
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  46.  12
    Malpractice & negligence: Arizona Court affirms immunity of organ donation personnel.J. Cohen - 1998 - Journal of Law, Medicine and Ethics 26 (4):360-364.
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  47.  22
    Culpable Carelessness: Recklessness and Negligence in the Criminal Law.Findlay Stark - 2016 - Cambridge University Press.
    The question of when a person is culpable for taking an unjustified risk of harm has long been controversial in Anglo-American criminal law doctrine and theory. This survey of the approaches adopted in England and Wales, Canada, Australia, the United States, New Zealand and Scotland argues that they are converging, to differing extents, around a 'Standard Account' of culpable unjustified risk-taking. This Standard Account distinguishes between awareness-based culpability and inadvertence-based culpability for unjustified risk-taking. With reference to criminal law theory and (...)
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  48. Responsibility and the Negligence Standard.Joseph Raz - 2010 - Oxford Journal of Legal Studies 30 (1):1-18.
    The paper has dual aim: to analyse the structure of negligence, and to use it to offer an explanation of responsibility (for actions, omissions, consequences) in terms of the relations which must exist between the action (omission, etc.) and the agents powers of rational agency if the agent is responsible for the action. The discussion involves reflections on the relations between the law and the morality of negligence, the difference between negligence and strict liability, the role of excuses and the (...)
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  49.  4
    Negligent Samaritans Are No Good.George J. Annas - 1979 - Journal of Law, Medicine and Ethics 7 (1):4-4.
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  50. Negligent Rape.David Archard - 1999 - Australian Journal of Professional and Applied Ethics 1 (2).
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