A role of perirhinal cortex (PrC) in recognition memory for objects has been well established. Contributions of parahippocampal cortex (PhC) to this function, while documented, remain less well understood. Here, we used fMRI to examine whether the organization of item-based recognition memory signals across these two structures is shaped by object category, independent of any difference in representing episodic context. Guided by research suggesting that PhC plays a critical role in processing landmarks, we focused on three categories of objects that (...) differ from each other in their landmark suitability as confirmed with behavioral ratings (buildings > trees > aircraft). Participants made item-based recognition-memory decisions for novel and previously studied objects from these categories, which were matched in accuracy. Multi-voxel pattern classification revealed category-specific item-recognition memory signals along the long axis of PrC and PhC, with no sharp functional boundaries between these structures. Memory signals for buildings were observed in the mid to posterior extent of PhC, signals for trees in anterior to posterior segments of PhC, and signals for aircraft in mid to posterior aspects of PrC and the anterior extent of PhC. Notably, item-based memory signals for the category with highest landmark suitability ratings were observed only in those posterior segments of PhC that also allowed for classification of landmark suitability of objects when memory status was held constant. These findings provide new evidence in support of the notion that item-based memory signals for objects are not limited to PrC, and that the organization of these signals along the longitudinal axis that crosses PrC and PhC can be captured with reference to landmark suitability. (shrink)

By utilizing new information from both clinical and experimental (lesion, electrophysiological, and gene-activation) studies with animals, the anatomy underlying anterograde amnesia has been reformulated. The distinction between temporal lobe and diencephalic amnesia is of limited value in that a common feature of anterograde amnesia is damage to part of an comprising the hippocampus, the fornix, the mamillary bodies, and the anterior thalamic nuclei. This view, which can be traced back to Delay and Brion (1969), differs from other recent models in (...) placing critical importance on the efferents from the hippocampus via the fornix to the diencephalon. These are necessary for the encoding and, hence, the effective subsequent recall of episodic memory. An additional feature of this hippocampalanterior thalamic and the perirhinal–medial dorsal thalamic systems are compromised, leading to severe deficits in both recall and recognition. (shrink)

We present an investigation into the relation between design princi- ples in Japanese gardens, and their associated perceptual effects. This leads to the realization that a set of design principles described in a Japanese gardening text by Shingen (1466), shows many parallels to the visual effects of perceptual grouping, studied by the Gestalt school of psychology. Guidelines for composition of rock clusters closely relate to perception of visual figure. Garden design elements are arranged into patterns that simplify figure-ground segmentation, while (...) seemingly balancing the visual salience of subparts and the global arrangement. Visual ‘ground’ is analyzed via medial axis transformation (MAT), often associated with shape perception in humans. MAT analysis reveals implicit structure in the visual ground of a quintessential rock garden design. The MAT structure enables formal com- parison of structure of figure and ground. They share some aesthetic qualities, with interesting differences. Both contain naturalistic asymmetric, self-similar, branching structures. While the branching pattern of the ground converges towards the viewer, that of the figure converges in the opposite direction. (shrink)

We present an investigation into the relation between design principles in Japanese gardens, and their associated perceptual effects. This leads to the realization that a set of design principles described in a Japanese gardening text by Shingen (1466), shows many parallels to the visual effects of perceptual grouping, studied by the Gestalt school of psychology. Guidelines for composition of rock clusters closely relate to perception of visual figure. Garden design elements are arranged into patterns that simplify figure-ground segmentation, while seemingly (...) balancing the visual salience of subparts and the global arrangement. Visual ‘ground’ is analyzed via medial axis transformation (MAT), often associated with shape perception in humans. MAT analysis reveals implicit structure in the visual ground of a quintessential rock garden design. The MAT structure enables formal comparison of structure of figure and ground. They share some aesthetic qualities, with interesting differences. Both contain naturalistic asymmetric, self-similar, branching structures. While the branching pattern of the ground converges towards the viewer, that of the figure converges in the opposite direction. (shrink)

This paper connects ideas from twentieth century Gestalt psychology, experiments in vision science, and Maurice Merleau-Ponty’s phenomenology of perception. I propose that when we engage in simple sensorimotor tasks whose successful completion is open, our behavior may be motivated by practical perceptual awareness alone, responding to invariant features of the perceptual field that are invisible to other forms of perceptual awareness. On this view, we see more than we think we see, as evidenced by our skillful bodily behavior.

ObjectivesTo simulate hemodynamic changes after extraluminal compression in pulsatile tinnitus patients with a prominent transverse-sigmoid sinus junction.MethodsOne patient-specific case was reconstructed based on computed tomography venography images of a PT patient. The compression degree served as a new index in this study. Cases with 10, 20, 30, 40, 50, 60, 70, 80, and 90% of the compression degree of the control subject were constructed. Steady-state computational fluid dynamics were assessed. The wall pressure distribution, wall maximum pressure and flow pattern of (...) the PTSJ were calculated to evaluate hemodynamic differences among all cases.ResultsWith increasing compression, the wall pressure at the compression point and downstream of the PTSJ decreased but increased upstream. When the compression degree exceeded 70%, the upstream pressure increased significantly. Above 50% compression, the blood flow pattern downstream of the sigmoid sinus tended to spiral, especially after 80% compression. Beyond 60% compression, the blood flow pattern under the compression axis became more medial.ConclusionMechanical compression of PTSJ changes wall pressure and blood flow patterns. The degree of compression should be carefully observed to avoid possible complications or reoccurrence. (shrink)

BackgroundThe preferable position of Deep Brain Stimulation electrodes is proposed to be located in the dorsolateral subthalamic nucleus to improve general motor performance. The optimal DBS electrode localization for the post-operative improvement of balance and gait is unknown.MethodsIn this single-center, retrospective analyses, 66 Parkinson’s disease patients were assessed pre- and post-operatively by using MDS-UPDRS, freezing of gait score, Giladi’s gait and falls questionnaire and Berg balance scale. The clinical outcome was related to the DBS electrode coordinates in x, y, z (...) plane as revealed by image-based reconstruction. Binomial generalized linear mixed models with fixed-effect variables electrode asymmetry, parkinsonian subtype, medication, age class and clinical DBS induced changes were analyzed.ResultsSubthalamic nucleus-deep brain stimulation improved all motor, balance and FoG scores in MED OFF condition, however there were heterogeneous results in MED ON condition. DBS electrode reconstructed coordinates impacted the responsiveness of axial symptoms. FoG and balance responders showed slightly more medially located STN electrode coordinates and less medio-lateral asymmetry of the electrode reconstructed coordinates across hemispheres compared to non-responders.ConclusionDeep brain stimulation electrode reconstructed coordinates, particularly electrode asymmetry on the medio-lateral axis affected the post-operative responsiveness of balance and FoG symptoms in PD patients. (shrink)

Bei der Rezeption von Kunst treten vier Faktoren ins Spiel: Als Bedingungen der Wahrnehmung fungieren Wissensbestände, entsprechende Präsentationsbedingungen sowie - nicht zuletzt - das Medium des Geldes. Sie bilden ein Rahmensystem, durch das ein Werk erst in Erscheinung zu treten vermag. Einschliesslich des rezipierten Gegenstandes, der den vierten Faktor in diesem Geschehen abgibt, stehen alle Faktoren in stetiger Wechselwirkung.

How can the medium be addressed when it is always already saturated in religious over-determinations and ever marked by theological concerns (such as revelation and incarnation) while, at the same time, religion would not be practiced and theology not be done without using some such medium? We encourage methodological and conceptual shifts, first, from medium to mediality; second, from religion to its partial negation (or, perhaps, partial permeation); third, from theology to doing the theological differently. With these shifts we desire (...) to initiate, continue, and intensify debates, specifically between theologians and scholars of religious studies and media theory. (shrink)

As Foucault has argued persuasively, human sciences carry in themselves not only the danger of anthropologization, but, precisely because of their epistemic instability and hybridity, also the potential for its criticism. This criticism is all the more important in the current turn to the human being as living, sentient and affective being, which takes place under the sign of life- and brain-sciences. Thus, it serves as the starting point of the medial anthropology and its focus on the medium of (...) the game that this paper presents. German Die Wissenschaften vom Menschen tragen, wie Foucault überzeugend argumentierte, nicht nur die Gefahr der Anthropologisierung, sondern, gerade aufgrund ihrer epistemischen Instabilität und Hybridität auch das Potential zu deren Kritik in sich. Diese Kritik ist in der gegenwärtigen – im Zeichen der Lebens- und Neurowissenschaften stattfindenden – Hinwendung zum Menschen als lebendes, empfindendes und affektives Wesen in neuer Weise aktuell. Sie bildet den Ausgangspunkt der hier vorgestellten medialen Anthropologie und deren Fokussierung auf das Medium des Spiels. (shrink)

As Foucault has argued persuasively, human sciences carry in themselves not only the danger of anthropologization, but, precisely because of their epistemic instability and hybridity, also the potential for its criticism. This criticism is all the more important in the current turn to the human being as living, sentient and affective being, which takes place under the sign of life- and brain-sciences. Thus, it serves as the starting point of the medial anthropology and its focus on the medium of (...) the game that this paper presents. (shrink)

It is shown that all the assumptions for symmetric monoidal categories follow from a unifying principle involving natural isomorphisms of the type →, called medial commutativity. Medial commutativity in the presence of the unit object enables us to define associativity and commutativity natural isomorphisms. In particular, Mac Lane’s pentagonal and hexagonal coherence conditions for associativity and commutativity are derived from the preservation up to a natural isomorphism of medial commutativity by the biendofunctor . This preservation boils down (...) to an isomorphic representation of the Yang–Baxter equation of symmetric and braid groups. The assumptions of monoidal categories, and in particular Mac Lane’s pentagonal coherence condition, are explained in the absence of commutativity, and also of the unit object, by a similar preservation of associativity by the biendofunctor . In the final section one finds coherence conditions for medial commutativity in the absence of the unit object. These conditions are obtained by taking the direct product of the symmetric groups for 0≤i≤n. (shrink)

Bilder haben seit je her das Vermögen, sich als Metamalerei reflexiv mit den Bedingungen ihrer eigenen Bildlichkeit auseinander zu setzen. In Momenten,medialer Vanitas’, wie sie der Beitrag nachvollzieht, ist es die Symbolik der Vanitas, welche gegen das Bild als solches gerichtet wird. Schon im Barock entstehen sie mit so unterschiedlichen Werken wie jenen Cornelius Norbertus Gijsbrechts und Michelangelo Merisi da Caravaggios, die als spezifisch,thanatologische Metamalerei‘ bezeichnet werden können. Sie zielen auf die mortifzierenden Strukturen bildlicher Repräsentation, ihre Medialität und Materialität. Doch (...) auch in zahlreichen zeitgenössischen Bildern von Marlene Dumas finden sich solch selbstreflexive Momente medialer Vanitas und damit moderne Transformationen eines vormodernen Topos. (shrink)

Bilder haben seit je her das Vermögen, sich als Metamalerei reflexiv mit den Bedingungen ihrer eigenen Bildlichkeit auseinander zu setzen. In Momenten,medialer Vanitas’, wie sie der Beitrag nachvollzieht, ist es die Symbolik der Vanitas, welche gegen das Bild als solches gerichtet wird. Schon im Barock entstehen sie mit so unterschiedlichen Werken wie jenen Cornelius Norbertus Gijsbrechts und Michelangelo Merisi da Caravaggios, die als spezifisch,thanatologische Metamalerei‘ bezeichnet werden können. Sie zielen auf die mortifzierenden Strukturen bildlicher Repräsentation, ihre Medialität und Materialität. Doch (...) auch in zahlreichen zeitgenössischen Bildern von Marlene Dumas finden sich solch selbstreflexive Momente medialer Vanitas und damit moderne Transformationen eines vormodernen Topos. (shrink)

One lingering, unresolved dimension of intermediality theory is the status of mediality itself. Typically, the concept of intermediality is offered as a challenge to the idea that media exist as “isolated monads” ; the task of the analyst then becomes that of thinking through the variety of relationships between them. The risk is that this conception of intermediality may work to hypostatize media as particular kinds of objects. In this hypostatization, work on intermediality has sometimes diverged in important ways from (...) the ongoing development of ideas about mediality itself. Mediality is best seen, I would argue, not as a permanent and definitive property of objects or forms but as the occasional.. (shrink)

Aggleton & Brown propose that familiarity-based recognition depends on a perirhinal-medial dorsal thalamic system. However, connections between these structures are sparse or absent. In contrast, the perirhinal cortex is connected to midline/intralaminar nuclei. In a human, a lesion in this thalamic domain, sparing the medial dorsal nucleus, impaired familiarity-based recognition while sparing recollective-based recognition. It is thus more likely that the intralaminar/midline nuclei are involved in recognition.

Axis specification is the first step in defining specific regions of the developing embryo. Embryos exploit asymmetries, either pre‐existing in the egg or triggered by external cues, to establish embryonic axes. The axial information is then used to generate regional differences within the embryo. In this review, we discuss experiments in animals which address three questions: whether the unfertilized egg is constructed with pre‐determined axes, what cues are used to specify the embryonic axes, and how these cues are interpreted (...) to generate the initial regional differences within the embryo. Based on mapping the data onto an animal phylogeny, we then propose a scenario for how this primary developmental decision occurred in ancestral metazoans. (shrink)

With great sympathy for Roman Ingarden and his work, Edith Stein edited his book project The Literary Work Of Art. In the letters she exchanges with him shereflects on relationship between reality and ideality: she writes that those who do not see the world as a reality must be fools. The political events in the 1930s had an impact on phenomenology. While Edmund Husserl dissociates himself from his protégé Martin Heidegger with regard to the content of his philosophy as well (...) as with regard to his ideology, Edith Stein distances herself more and more from the phenomenological method, seeing it as removed from reality, and she eventually become a Carmelite nun. Roman Ingarden, on the other hand, reconsiders interpreting phenomenology as aesthetic theory. Literature and film are being re-analysed in terms of phenomenological mediality and as factors of human communication. (shrink)

In light of developments within the field of media theory, a certain consensus has evolved in favour of approaches like mediatization and mediation. While these approaches above all focus on societal change from a media-dependent point of view, this article addresses the reverse side of these processes, asking about media users' appropriation of media in order to experience sociality that has only just been enabled by media-use. This awareness of medial terms and conditions is characterized as recipients' acknowledgment as (...) well as utilization of medial constraints, which is subsequently referred to as mediality. (shrink)

This commentary focuses on the “olfactory cortices–hippocampal formation” axis, proposed by Aboitiz et al. to be that network which allowed the first mammals to create elaborate representations of space. I argue here that this neural axis can be extended to a triangle of structures which also includes the orbital cortex.

ZusammenfassungDie Molekulargenetik bietet seit ein paar Jahren völlig neue Zugänge zur menschlichen Vergangenheit. Das noch junge und sehr dynamische Forschungsfeld der Archäogenetik nimmt für sich in Anspruch, Geschichte schreiben zu können, und zwar über alte DNA. Durch zahlreiche beachtenswerte Veröffentlichungen hat es viel Aufmerksamkeit erzeugt und erfahren – nicht nur im wissenschaftlichen Diskurs, sondern auch in den Medien. Allerdings erfährt die mediale Berichterstattung von der Forschung bisher wenig Beachtung. Auch der Forumsbeitrag kann dieses Desiderat nicht beheben, sucht aber – mit (...) einem exemplarischen Blick auf die Presseberichterstattung – erste Tendenzen einzufangen. Dies geschieht anhand von drei Thesen, sie lauten: Erfolgsgeschichten erzählen, Grenzen ziehen und konformistisch schreiben.In recent years molecular genetics has provided a completely new approach/access to the human past. The still new and quite dynamic research field of archaeogenetics claims to be able to write history using ancient DNA. Through numerous remarkable publications it has generated and received much interest not only in scientific discourse but also in the media. So far, however, scientists have not paid much attention to this coverage–a research desideratum this paper cannot resolve. But by looking at selected press clippings it seeks to capture first trends according to the following three theses: telling success stories, drawing boundaries, and writing in a conformist manner. (shrink)

ZusammenfassungDie Molekulargenetik bietet seit ein paar Jahren völlig neue Zugänge zur menschlichen Vergangenheit. Das noch junge und sehr dynamische Forschungsfeld der Archäogenetik (auch Paläogenetik oder Genetic History) nimmt für sich in Anspruch, Geschichte schreiben zu können, und zwar über alte DNA. Durch zahlreiche beachtenswerte Veröffentlichungen hat es viel Aufmerksamkeit erzeugt und erfahren – nicht nur im wissenschaftlichen Diskurs, sondern auch in den Medien. Allerdings erfährt die mediale Berichterstattung von der Forschung bisher wenig Beachtung. Auch der Forumsbeitrag kann dieses Desiderat nicht (...) beheben, sucht aber – mit einem exemplarischen Blick auf die Presseberichterstattung – erste Tendenzen einzufangen. Dies geschieht anhand von drei Thesen, sie lauten: Erfolgsgeschichten erzählen, Grenzen ziehen und konformistisch schreiben. (shrink)

Auch in freiheitlichen Demokratien gibt es mediale Formen und Verfahren, die staatlich monopolisiert sind. Dies sind die Verfahren zur Sicherung und Stabilisierung der Echtheit von Geld und staatlichen Dokumenten, also den zentralen Medien von Ökonomie und Staat. Im Sinne einer noch zu schreibenden Mediengeschichte des Staates stellt der Aufsatz diese Formen und Verfahren der Echtheitssicherung dar und zeigt auf, wie immer wieder auf neue technologische Bedrohungen des medialen Monopols des Staates reagiert werden musste. Even in liberal democracies there are media (...) forms and procedures monopolized by the state. Such are the methods to secure and stabilize the authenticity of money and state documents, i.e. the central media of economy and the state. In terms of a media history of the state, the paper describes these forms and methods of securing authenticity and shows how the state had to respond to ever new technological threats to its media monopoly. (shrink)

Over the past twenty years, the concept of intermediality has emerged as a strategic response that has sought to bypass some of the ills that have plagued the university as an institution.1 Indeed, defined as the study of “nodes of relations, of relationship movements slow enough to seem immobile”, intermediality as an approach has helped fight against the hyper-specialization of research in the humanities. By conceiving of relationships as paramount, it has made it possible to view as counterintuitive the fragmented (...) approach to the real and its representations. Thereby, the social and cultural environment has been relocated to the center of analyses.. (shrink)

I offer a reading of Aristotle’s “doctrine of the mean” that avoids two pitfalls: taking it as truistic, and taking it as involving the bizarre thesis that whenever one acts as reason directs, one’s action is mid-way between some extremes. The crucial point is that while Aristotle denies the existence of useful general ethical truths, he himself offers truths about the likelihoods with which rationality will require actions of certain types; and it is with such truths that the statistical idea (...) of the mean gets a foothold in his theory of the virtues. (shrink)

I offer a reading of Aristotle’s “doctrine of the mean” that avoids two pitfalls: taking it as truistic, and taking it as involving the bizarre thesis that whenever one acts as reason directs, one’s action is mid-way between some extremes. The crucial point is that while Aristotle denies the existence of useful general ethical truths, he himself offers truths about the *likelihoods* with which rationality will require actions of certain types; and it is with such truths that the statistical idea (...) of the mean gets a foothold in his theory of the virtues. (shrink)

In the recent literature on the nature of sound, there is an emerging consensus rejection of what might be thought of as the scientifically informed commonsense position: that sounds, whatever else they may be, must be entities that mediate between the source of the sound and the subject hearing it. This paper offers an argument for such "medial" theories of sound. This argument is intended to shift attention from the two considerations that have dominated the debate thus far: the (...) relevant scientific facts about audition and the spatial phenomenology of auditory experience. (shrink)