The human genome project's lasting legacies are the emerging insights into human physiology and disease, and the ascendance of biology as the dominant science of the 21st century. Sequencing revealed that >90% of the human genome is not coding for proteins, as originally thought, but rather is overwhelmingly transcribed into non‐protein coding, or non‐coding, RNAs (ncRNAs). This discovery initially led to the hypothesis that most genomic DNA is “junk”, a term still championed by some geneticists and evolutionary biologists. In contrast, (...) molecular biologists and biochemists studying the vast number of transcripts produced from most of this genome “junk” often surmise that these ncRNAs have biological significance. What gives? This essay contrasts the two opposing, extant viewpoints, aiming to explain their bases, which arise from distinct reference frames of the underlying scientific disciplines. Finally, it aims to reconcile these divergent mindsets in hopes of stimulating synergy between scientific fields. (shrink)

Persian possesses a number of stative complex predicates with _dâshtan_ ‘to have’ that express certain kinds of mental state. I propose that these _possessive experiencer complex predicates_ be given a formal semantic treatment involving possession of a portion of an abstract quality by an individual, as in the analysis of property concept lexemes due to Francez and Koontz-Garboden (Language 91(3):533–563, 2015 ; Natural Language and Linguistic Theory 34:93–106, 2016 ; Semantics and morphosyntactic variation: Qualities and the grammar of property concepts, (...) Oxford University Press, 2017 ). Augmented with an analysis of prepositional phrases introducing the target of the mental state and an approach to gradability in terms of measure functions (Wellwood in Measuring predicates, PhD dissertation, University of Maryland, College Park, 2014 ), the analysis explains various properties of possessive experiencer complex predicates, including the behavior of target phrases, the ability of the non-verbal element to be modified by a range of adjectives, the direct participation of the non-verbal element in comparative constructions, and the ability of degree expressions to modify both the non-verbal element and the VP containing the complex predicate. Theoretically, the analysis ties transitive mental state expressions to the grammar and semantics of property concept sentences, which are expressed via possessive morphosyntax cross-linguistically, and connects with syntactic proposals that independently argue for a universal underlyingly possessive morphosyntax for mental state predicates (Noonan in Case and syntactic geometry, PhD dissertation, McGill University, 1992 ; Hale and Keyser in Prolegomenon to a theory of argument structure, MIT Press, 2002 ). The work here also motivates modifications to Francez and Koontz-Garboden’s original proposal, and opens new questions in the original empirical domain of the analysis of possessive predicating strategies for the expression of property concept sentences. (shrink)

If one had to identify the biggest change within the philosophical tradition in the twenty-first century, it would certainly be the rapid rise of experimental philosophy to address differences in intuitions about concepts. It is, therefore, surprising that the philosophy of medicine has so far not drawn on the tools of experimental philosophy in the context of a particular conceptual debate that has overshadowed all others in the field: the long-standing dispute between so-called naturalists and normativists about the concepts of (...) health and disease. In this paper, I defend and advocate the use of empirical methods to inform and advance this and other debates within the philosophy of medicine. (shrink)

Views from one of the most original cultural critics of the twentieth century, Walter Benjamin.

The idea that consciousness and complexity are closely related has been a major driver of the popularity of integrated information theory of consciousness, despite its major formal, phenomenological, and neuroscientific shortcomings. Here, I argue that we can recover this intuition by replacing its biologically neutral notion of complexity with an evolutionary one that I shall dub “pathological complexity.”.

Benenson et al. provide a compelling case for treating greater investment into self-protection among females as an adaptive strategy. Here, we wish to expand their proposed adaptive explanation by placing it squarely in modern state-based and behavioural life-history theory, drawing on Veit'spathological complexityframework. This allows us to make sense of alternative “lifestyle” strategies, rather than pathologizing them.

It can seem obvious that we live in a world governed by laws of nature, yet it was not until the seventeenth century that the concept of a law came to the fore. Ever since, it has been attended by controversy: what does it mean to say that Boyle's law governs the expansion of a gas, or that the planets obey the law of gravity? Laws are rules that permit calculations and predictions. What does the universe have to be like, (...) if it is to play by them? This book sorts the most prominent answers into three families. Laws first arose in a theological context; they govern events only because God enforces them. Those wishing to reverse the order of explanation, and argue that the powers of objects fix the laws, struggled to claim for themselves the results of new science. The stand-off between these two families bred a third which rejects any kind of enforcer for the laws. On this view, laws summarize events; they do not govern anything. This book traces the fortunes of the three families, from their origins to the present day. It uses objections - and the revisions needed to answer them - to produce the best representative of each. Along the way, it tries to settle the rules of this game, the debate over laws of nature. What should we expect from an account of laws? The book aims to help readers develop their own desiderata and judge the merits of the competing positions. (shrink)

Proponents of situated affectivity hold that “tools for feeling” are just as characteristic of the human condition as are “tools for thinking” or tools for carpentry. An agent’s affective life, they argue, is dependent upon both physical characteristics of the agent and the agent’s reciprocal relationship to an appropriately structured natural, technological, or social environment. One important achievement has been the distinction between two fundamentally different ways in which affectivity might be intertwined with the environment: the “user-resource-model” and the “mind-invasion-model.” (...) The twofold purpose of this paper is to complement the debate about situated affectivity in general and about “mind invasion” in particular by, firstly, connecting it to situationist research in social psychology and, secondly, broadening the perspective to not only accommodate decidedly detrimental “invasions” but also potentially beneficial forms of “mind shaping” that include the manipulation of an agent’s experiential life and behaviour through the moulding of both the agent’s environment and the agent’s body. (shrink)

Some biographical remarks and philosophical questions within philosophy for children -- Celebrating thirty years of philosophy for children -- Good-bye to Matthew Lipman (and Ann Margaret Sharp) -- The politics of formation : a critique of philosophy for children -- Philosophy at public schools of Brasilia, DF -- (Some) reasons for doing philosophy with children -- Philosophizing with children at a philosophy camp -- Does philosophy fit in Caxias? A Latin American project -- Philosophy as spiritual and political exercise in (...) an adult literacy course. (shrink)

Mental causation, our mind's ability to causally affect the course of the world, is part and parcel of our ‘manifest image’ of the world. That there is mental causation is denied by virtually no one. How there can be such a thing as mental causation, however, is far from obvious. In recent years, discussions about the problem of mental causation have focused on Jaegwon Kim's so-called Causal Exclusion Argument, according to which mental events are ‘screened off’ or ‘preempted’ by physical (...) events unless mental causation is a genuine case of overdetermination or mental properties are straightforwardly reducible to physical properties. (shrink)

This book explores the idea of a childlike education and offers critical tools to question traditional forms of education, and alternative ways to understand and practice the relationship between education and childhood. Engaging with the work of Michel Foucault, Jacques Rancière, Giorgio Agamben and Simón Rodríguez, it contributes to the development of a philosophical framework for the pedagogical idea at the core of the book, that of a childlike education.Divided into two parts, the book introduces innovative ideas through philosophical argument (...) and discussion, challenging existing understandings of what it means to teach or to form a child, and putting into question the idea of education as a process of formation. The first part of the book consists of a dialogue with a number of interlocutors in order to develop an original conception of education. The second part presents the idea of a childlike education, beginning with a discussion of the relationships between childhood and philosophy, and followed by a critique of the place of philosophical experience in a childhood of education. Instead of asking how philosophy might educate childhood, this book raises the question of how childhood might educate philosophy. It will be of key value to researchers, educators and postgraduate students in the fields of education and the human sciences. (shrink)

A number of studies have demonstrated pragmatic language difficulties in people with Schizophrenia Spectrum and Other Psychotic Disorders. However, research about how people with schizophrenia spectrum and other psychotic disorders understand scalar implicatures is surprisingly rare, since SIs have generated much of the most recent literature. Scalar implicatures are pragmatic inferences, based on linguistic expressions like some, must, or, which are part of a scale of informativeness. Logically, the less informative expressions imply the more informative ones, but pragmatically people usually (...) infer that the presence of a less informative term implies that the more informative term was not applicable. In one of the few existing studies with people with schizophrenia spectrum and other psychotic disorders, Wampers et al. observed that in general, people with schizophrenia spectrum and other psychotic disorders were less likely to derive SIs than controls. The current study has three main aims. First, we want to replicate the original finding with the scalar terms some-all. Second, we want to investigate how these patients deal with different scalar terms, that is, we want to investigate if scalar diversity is also observed in this clinical group. Third, we investigate the role of working memory, often seen as another important mechanism to enable inferring SIs. Twenty-one individuals with a psychotic disorder and 21 matched controls answered 54 under-informative statements, in which seven different pairs of scalar terms were used. In addition, working memory capacity was measured. Patients with schizophrenia spectrum and other psychotic disorders did not make more logical interpretations when processing quantifiers, disconfirming Wampers et al.. However, certain scalar scales elicited more pragmatic interpretations than others, which is in line with the scalar diversity hypothesis. Additionally, we observed only partial evidence for the role of working memory. Only for the scalar scale and-or, a significant effect of working memory was observed. The implications of these results for patients with schizophrenia spectrum and other psychotic disorders are discussed, but also the role of working memory for pragmatic inferences, as well as the place of SIs in experimental pragmatics. (shrink)

In a provocative 1991 paper, Alvin Moss and Mark Siegler argued that it may be fair to give individuals with alcohol-related end-stage liver disease lower priority for a liver transplant than those who develop end-stage liver disease from other factors. Like other organs, there is a substantial gap between the available livers for transplantation and the number of people who need liver transplants. Yet, unlike those with end-stage renal disease, who can survive for some time on dialysis before receiving a (...) kidney transplant, those with liver failure will die without a liver transplant. (shrink)

L'etude menee par Walter Biemel ne pretend nullement isoler et epuiser un concept de la philosophie de Heidegger, mais s'attache tout au contraire a suggerer une interpretation originales d'une pensee a partir de l'un de ses concepts fondamentaux. Pour saisir le probleme du monde, il apparait en effet necessaire de comprendre la structure fondamentale du Dasein. Que la problematique du monde soit intimement liee a celle de l'Etre, c'est ce qui se manifeste clairement dans la definition que donne Heidegger (...) du Dasein, au troisieme chapitre de Sein und Zeit, comme etre-dans-le-monde. De la comprehension de cette modalite d'etre ve dependre la saisie adequate des elements structurels du Dasein. Walter Biemel releve l'importance de cette nouvelle facon de concevoir le Dasein et le changement qu'elle apporte par rapport a la conception traditionnelle partant de l'ego pur. L'expression etre-dans-le-monde, loin de se resumer a une constatation de fait, possede pour Heidegger la signification d'une these ontologique. Bien plus qu'une simple determination spatiale s'epuisant dans l'extensio cartesienne, il s'agit la d'une attitude de familiarite, qui se decline selon divers types de reference du Dasein au monde. Etre-dans-le-monde signifie au fond: etre ouvert a l'Etre, se trouver placer dans l'eclaircie de l'Etre. (shrink)

In this radical reinterpretation of Aristotle's Metaphysics, Walter E. Wehrle demonstrates that developmental theories of Aristotle are based on a faulty assumption: that the fifth chapter of Categories is an early theory of metaphysics that Aristotle later abandoned.

There is no doubt that soybean is the most important crop for Argentina, with a planted surface that rose 11,000,000 hectares and a production of around 35,000,000 metric tons. During the 1990s, there was a significant agriculture transformation in the country, motorize by the adoption of transgenic crops (soy-bean, maize, and cotton) under the no-tillage system. The expansion of this model has been spread not only in the Pampas but also in very rich areas with high biodiversity, opening a new (...) agricultural border to important eco-regions like the Yungas, Great Chaco, and the Mesopotamian Forest. Transgenic cropping is a powerful technology. This produced relevant transformations over the environment and society where it is allowed. Migration, concentration of agribusiness, and loss of food sovereignty are some of the social results. Landscape transformation in the rural sector is evident, and the appearance of tolerance weeds to glyphosate is a reality. Nutrient depletion, soil-structure degradation, potential desertification, and loss of species are other consequences on the environmental level. (shrink)

Sociology has a subject matter that is constantly changing. That is why it has to keep reformulating its theories and categories. One example is the profound change of housing during the course of industrial urbanization. This change is described as a change from the whole household (O. Brunner) to housing as part of the modern way of living based on the functional, social, socio-psychological, and economic dimensions of living. In connection with this change, the two basic aspects of the housing (...) question are discussed: What defines a human habitat and why are new housing problems constantly emerging? (shrink)