The return of individual research results and incidental findings from biobanking research is a much debated ethical issue globally but has extensive relevance in India where the burden of out of pocket health care expenses is high for the majority. The views of 21 ethics committee (EC) members and 22 researchers from Bengaluru, India, concerning the ethics of biobanking research were sought through in‐depth interviews using an unfolding case vignette with probes. A shared view among most was that individual research (...) results which are ‘actionable’ or have ‘clinical significance’ should be returned to the sample contributors through their treating physicians. This was seen as an ethical obligation and a moral duty on the side of the researcher to “give back” to the person who contributed to the research. The challenges foreseen were that of resources, both financial and personnel, for the time and counseling needed to accompany the disclosure of results. Perceptions of ‘ownership’ appear to influence the concept of benefit sharing. While benefit sharing in financial terms was considered ethically challenging, certain researchers and ethics committee members made a case for “two way altruism” where the researcher in return for the altruistic ‘valuable contribution’, shares with the contributor/ community, benefits of the research which could include research findings, improved patient care, and more affordable access to the new diagnostic tests or products arising from the research. This defines the emerging ethic of “giving back” which goes beyond individual rights and ensures reciprocity and distributive justice. (shrink)

On Advaita philosophy; Sanskrit text with commentary and translation.

RAID-II is a high-bandwidth, network-attached storage server designed and implemented at the University of California at Berkeley. In this paper, we measure the performance of RAID-II and evaluate various architectural decisions made during the design process. We first measure the end-to-end performance of the system to be approximately 20 MB/s for both disk array reads and writes. We then perform a bottleneck analysis by examining the performance of each individual subsystem and conclude that the disk subsystem limits performance. By adding (...) a custom interconnect board with a high-speed memory and bus system and parity engine, we are able to achieve a performance speedup of 8 to 15 over a comparative system using only off-the-shelf hardware. (shrink)

Ni-44 at.% Al and Ni-50 at.% Al single crystals were tested in compression in the hard d 001 ¢ orientation. The dislocation processes and deformation behaviour were studied as a function of temperature, strain and strain rate. A slip transition in NiAl occurs from a d 111 ¢ slip to non- a d 111 ¢ slip at intermediate temperatures. In Ni-50 at.% Al single crystals, only a d 010 ¢ dislocations are observed above the slip transition temperature. In contrast, a (...) d 101 ¢ {101} glide has been observed to control deformation beyond the slip transition temperature in Ni-44 at.% Al. a d 101 ¢ dislocations are observed primarily along both d 111 ¢ directions in the glide plane. High-resolution transmission electron microscopy observations show that the core of the a d 101 ¢ dislocations along these directions is decomposed into two a d 010 ¢ dislocations, separated by a distance of approximately 2 nm. The temperature window of stability for these a d 101 ¢ dislocations depends upon the strain rate. At a strain rate of 1.4 2 10 m 4 s m 1 , a d 101 ¢ dislocations are observed between 800 and 1000 K. Complete decomposition of a d 101 ¢ dislocations into a d 010 ¢ dislocations occurs beyond 1000 K, leading to a d 010 ¢ climb as the deformation mode at higher temperatures. At lower strain rates, decomposition of a d 101 ¢ dislocations has been observed to occur along the edge orientation at temperatures below 1000 K. Embedded-atom method calculations and experimental results indicate that a d 101 ¢ dislocations have a large Peierls stress at low temperatures. Based on the present microstructural observations and a survey of the literature with respect to vacancy content and diffusion in NiAl, a model is proposed for a d 101 ¢ {101} glide in Ni-44 at.% Al, and for the observed yield strength versus temperature behaviour of Ni-Al alloys at intermediate and high temperatures. (shrink)

This monograph attempts to clarify one significant but much neglected aspect of Peirce's contribution to the philosophy of science. It was written in 1963 as my M. A. thesis at the Uni versity of Illinois. Since the topic is still neglected it is hoped that its pUblication will be of use to Peirce scholars. I should like to acknowledge my indebtedness to Dr. Max Fisch who broached this topic to me and who advised me con tinuously through its development, assisting (...) generously with his own insights and unpublished Peirce manuscripts. TABLE OF CONTENTS INTRODUCTION 1. A Current Issue in the Philosophy of Science 1 2. Peirce and His Theory of Abduction 5 3. The General Character of Abduction 7 PART I: THE EARLY THEORY 1. Peirce's Earliest Conception of Inference 11 2. Three Kinds of Inference and Three Figures of Syllogism 13 3. Ampliative Inference and Cognition 17 4. Induction and Hypothesis 20 5. The Method of Methods 23 PART II: THE LATER THEORY 1. The Transitional Period 28 2. Three Stages of Inquiry 31 3. Abduction and Guessing Instinct 35 4. Logic as a Normative Science 38 5. Hypothesis Construction and Selection 41 6. Abduction and Pragmatism 44 7. Economy of Research 47 8. Justification of Abduction 51 CONCLUSION 55 61 BIBLIOGRAPHY INTRODUCTION 1. (shrink)

In our article (Zawadzki and Adamczyk 2021), we analyzed threats that novel memory modifying interventions may pose in the future. More specifically, we discussed how optogenetics’ potential for reversible erasure/deactivation of memory “may impact authenticity by producing changes at different levels of personality.” Our article has received many thoughtful open peer commentaries for which we would like to express our great appreciation. We have identified two main threads of objections. They are related to the potential applicability of optogenetics as a (...) therapeutic memory modification technology (MMT) in humans—applicability thread, and the normative value of authenticity, that is, the assumption that preserving authenticity is valuable (either in general or in the particular approach we adopted)—normative thread. Both of these threads concern fundamental issues: The former deals with the scientific credibility of the case vignette on which our discussion is based, and the latter deals with the normative weight of our considerations. We think that addressing both of them can be instructive in a broader context as they reflect a more general disagreement among neuroethicists about the very purpose and method of our discipline. (shrink)

Is the societal-level of analysis sufficient today to understand the values of those in the global workforce? Or are individual-level analyses more appropriate for assessing the influence of values on ethical behaviors across country workforces? Using multi-level analyses for a 48-society sample, we test the utility of both the societal-level and individual-level dimensions of collectivism and individualism values for predicting ethical behaviors of business professionals. Our values-based behavioral analysis indicates that values at the individual-level make a more significant contribution to (...) explaining variance in ethical behaviors than do values at the societal-level. Implicitly, our findings question the soundness of using societal-level values measures. Implications for international business research are discussed. (shrink)

The author introduces and critically analyzes two recent, curious findings and their accompanying explanations regarding how the folk intuits the capabilities of the dead and those in a persistent vegetative state. The dead are intuited to survive death, whereas PVS patients are intuited as more dead than the dead. Current explanations of these curious findings rely on how the folk is said to conceive of death and the dead: either as the annihilation of the person, or that person’s continuation as (...) a disembodied being. The author argues that these two conceptions are incompatible and inconsistent with each other and the evidence. Contrariwise, the author argues that the folk intuition about dead-survivors and the living dead are more easily explained by appealing to cross-culturally established concepts: the folk biological concept of death the existential concept of death, and the concept of social death. (shrink)

The covariant Klein-Gordon equation requires twice the boundary conditions of the Schrödinger equation and does not have an accepted single-particle interpretation. Instead of interpreting its solution as a probability wave determined by an initial boundary condition, this paper considers the possibility that the solutions are determined by both an initial and a final boundary condition. By constructing an invariant joint probability distribution from the size of the solution space, it is shown that the usual measurement probabilities can nearly be recovered (...) in the non-relativistic limit, provided that neither boundary constrains the energy to a precision near ℏ/t 0 (where t 0 is the time duration between the boundary conditions). Otherwise, deviations from standard quantum mechanics are predicted. (shrink)

J. L. Austin (1911-1960) exercised in Post-war Oxford an intellectual authority similar to that of Wittgenstein in Cambridge. Although he completed no books of his own and published only seven papers, Austin became through lectures and talks one of the acknowledged leaders in what is called ‘Oxford philosophy’ or ‘ordinary language philosophy’. Few would dispute that among analytic philosophers Austin stands out as a great and original philosophical genius. Three volumes of his writing, published after his death, have become classics (...) in analytical philosophy: Philosophical Papers ; Sense and Sensibilia ; and How to Do Things with Words . First published in 1969, this book is a collection of critical essays on Austin’s philosophy written by well-known philosophers, many of whom knew Austin personally. A number of essays included were especially written for this volume, but the majority have appeared previously in various journals or books, not all easy to obtain. (shrink)

A time-symmetric formulation of nonrelativistic quantum mechanics is developed by applying two consecutive boundary conditions onto solutions of a time- symmetrized wave equation. From known probabilities in ordinary quantum mechanics, a time-symmetric parameter P0 is then derived that properly weights the likelihood of any complete sequence of measurement outcomes on a quantum system. The results appear to match standard quantum mechanics, but do so without requiring a time-asymmetric collapse of the wavefunction upon measurement, thereby realigning quantum mechanics with an important (...) fundamental symmetry. (shrink)

Developing the Horizons of the Mind is a comprehensive book on Relational and Contextual Reasoning, a theory of the human mind which powerfully addresses key areas of human conflict such as the ideological conflict between nations, the conflict in close relationships and the conflict between science and religion. K. Helmut Reich provides a clear and accessible introduction to the fresh RCR way of thinking that encourages people to adopt an inclusive rather than an oppositional approach to conflict and problem-solving. Part (...) one outlines the key aspects of RCR theory and supporting empirical data and part two provides examples of its application in the world. RCR provides a stimulating and challenging tool to several disciplines, including philosophy, psychology, religious studies and education, and this book will be a valuable resource for cognitive scientists, psychotherapists, theologians, educators and all those involved in conflict resolution. (shrink)

I argue that there is a version of (quasi-Armstrongian) weak illusionism that intelligibly relates phenomenal concepts and introspective opacity, accounts for the (hard) problem intuitions Chalmers highlights (modal, epistemic, explanatory, and metaphysical), and undermines the most important arguments Chalmers deploys against type-B and type-C materialisms. If this is successful, we can satisfactorily account for the meta-problem of consciousness, mollify our hard problem intuitions, and remain genuine realists about phenomenal experience.

In mirror mark tests dolphins twist, posture, and engage in open-mouth and head movements, often repetitive. Because postures and an open mouth are also dolphin social behaviours, we used self-view television as a manipulatable mirror to distinguish between self-examination and social behavior. Two dolphins were exposed to alternating real-time self-view and playback of the same to determine if they distinguished between them. The adult male engaged in elaborate open-mouth behaviors in mirror mode, but usually just watched when playing back the (...) same material. Mirror mode behavior was also compared to interacting with real dolphins . Mark tests were conducted, as well as switches from front to side self-views to see if the dolphins turned. They presented marked areas to self-views to see if the dolphins turned. They presented marked areas to the self-view television and turned. The results suggest self-examination over social behavior. (shrink)

This article provides current Schwartz Values Survey (SVS) data from samples of business managers and professionals across 50 societies that are culturally and socioeconomically diverse. We report the society scores for SVS values dimensions for both individual- and societal-level analyses. At the individual-level, we report on the ten circumplex values sub-dimensions and two sets of values dimensions (collectivism and individualism; openness to change, conservation, self-enhancement, and self-transcendence). At the societal-level, we report on the values dimensions of embeddedness, hierarchy, mastery, affective (...) autonomy, intellectual autonomy, egalitarianism, and harmony. For each society, we report the Cronbach’s α statistics for each values dimension scale to assess their internal consistency (reliability) as well as report interrater agreement (IRA) analyses to assess the acceptability of using aggregated individual level values scores to represent country values. We also examined whether societal development level is related to systematic variation in the measurement and importance of values. Thus, the contributions of our evaluation of the SVS values dimensions are two-fold. First, we identify the SVS dimensions that have cross-culturally internally reliable structures and within-society agreement for business professionals. Second, we report the society cultural values scores developed from the twenty-first century data that can be used as macro-level predictors in multilevel and single-level international business research. (shrink)

Written by leading researchers in educational and social psychology, learning science, and neuroscience, this edited volume is suitable for a wide-academic readership. It gives definitions of key terms related to motivation and learning alongside developed explanations of significant findings in the field. It also presents cohesive descriptions concerning how motivation relates to learning, and produces a novel and insightful combination of issues and findings from studies of motivation and/or learning across the authors' collective range of scientific fields. The authors provide (...) a variety of perspectives on motivational constructs and their measurement, which can be used by multiple and distinct scientific communities, both basic and applied. (shrink)

Papers presented at an annual inter-disciplinary seminar held to facilitate the 60th birthday of Kalarikkal Poulose Aleaz, b. 1947, theologist from Kerala, India during 20-21 September 2007.