Is Big Data science a whole new way of doing research? And what difference does data quantity make to knowledge production strategies and their outputs? I argue that the novelty of Big Data science does not lie in the sheer quantity of data involved, but rather in the prominence and status acquired by data as commodity and recognised output, both within and outside of the scientific community and the methods, infrastructures, technologies, skills and knowledge developed to handle data. These developments (...) generate the impression that data-intensive research is a new mode of doing science, with its own epistemology and norms. To assess this claim, one needs to consider the ways in which data are actually disseminated and used to generate knowledge. Accordingly, this article reviews the development of sophisticated ways to disseminate, integrate and re-use data acquired on model organisms over the last three decades of work in experimental biology. I focus on online databases as prominent infrastructures set up to organise and interpret such data and examine the wealth and diversity of expertise, resources and conceptual scaffolding that such databases draw upon. This illuminates some of the conditions under which Big Data needs to be curated to support processes of discovery across biological subfields, which in turn highlights the difficulties caused by the lack of adequate curation for the vast majority of data in the life sciences. In closing, I reflect on the difference that data quantity is making to contemporary biology, the methodological and epistemic challenges of identifying and analysing data given these developments, and the opportunities and worries associated with Big Data discourse and methods. (shrink)

Sabina Alkire shows how Nobel Prize-winning economist Amartya Sen's capability approach can be coherently---and practically---put to work in poverty reduction activities so that the voices and values of the poor matter. This provides economists, philosophers, theologians, and development practitioners with a way forward that addresses both theoretical and practical challenges.

We propose an account of the subject’s cognition that allows for a full articulation of the phenomenon of ideology. We argue that ideology operates at the level of the a priori: it transcendentally conditions the intelligibility of thought and practice. But we draw from strands of post-Kantian philosophy of science and social philosophy in repudiating Kant’s view that the a priori is necessary and fixed. Instead, we argue, it is contingent, and therefore revisable. More precisely, it is conditioned materially: it (...) must be understood as an activity, continuous with and shaped by material social practice. We conclude with some remarks about the possibility of agency over one’s relativized, materially conditioned a priori; that is, over the possibility of critique. (shrink)

Against the background of a new Ten Commandments for the Polish business community a new course in business ethics is now being offered to students in the Faculty of Management and Economy of the Technical University of Gdańsk, ul. G. Narutowicza 11/12, 80‐952 Gdańsk, Poland. Dr Kinach‐Brzozowska, who introduced the course last year, describes its content and her students’needs and reactions.

Este texto tiene por objetivo investigar los orígenes del movimiento ideológico anarco-feminista en el Río de la Plata, examinando las circunstancias históricas que propiciaron su surgimiento y que lo caracterizaron. Analizando sus posturas y opiniones contenidas en su principal medio impreso de difusión: el periódico La Voz de la Mujer, las bases de su pensamiento crítico, libertario y emancipatorio respecto a la condición de la mujer, contenidos en su consigna: ni dios, ni patrón, ni marido. Así como sus repercusiones en (...) las transformaciones sociales que se gestaron a finales del siglo XIX.Palabras clave: Feminismo. Anarquismo. Río de la Plata. La Voz de la Mujer. AbstractThis text aims to investigate the origins of the anarcho-feminist ideological movement in the Río de la Plata, examining the historical circumstances that led to its emergence and characterized it. Analyzing their positions and opinions contained in their main print media: the newspaper La Voz de la Mujer, the bases of their critical, libertarian and emancipatory thinking regarding the condition of the women, contained in their slogan: neither god, nor boss, nor husband. As well as its repercussions in the social transformations that took place at the end of the 19th century.Keywords: Feminism. Anarchism. Río de la Plata. La Voz de la Mujer. (shrink)

This groundbreaking, open access volume analyses and compares data practices across several fields through the analysis of specific cases of data journeys. It brings together leading scholars in the philosophy, history and social studies of science to achieve two goals: tracking the travel of data across different spaces, times and domains of research practice; and documenting how such journeys affect the use of data as evidence and the knowledge being produced. The volume captures the opportunities, challenges and concerns involved in (...) making data move from the sites in which they are originally produced to sites where they can be integrated with other data, analysed and re-used for a variety of purposes. The in-depth study of data journeys provides the necessary ground to examine disciplinary, geographical and historical differences and similarities in data management, processing and interpretation, thus identifying the key conditions of possibility for the widespread data sharing associated with Big and Open Data. The chapters are ordered in sections that broadly correspond to different stages of the journeys of data, from their generation to the legitimisation of their use for specific purposes. Additionally, the preface to the volume provides a variety of alternative “roadmaps” aimed to serve the different interests and entry points of readers; and the introduction provides a substantive overview of what data journeys can teach about the methods and epistemology of research. (shrink)

A critical discussion of three recent monographs on Kantian ethics: Jens Timmermann's Kant's Will at the Crossroads, Barbara Herman's The Moral Habitat, and Mark Timmons' Kant's Doctrine of Virtue. I start by laying out some of the main claims of all three works, and then examine some of the main points of contention between them: principally, the issue of moral complexity, the derivation of duties, and the distinction between theoretical and practical reason. I conclude with some remarks on how the (...) insights of all three works might be fruitfully combined to advance the current state of thought on the structure and composition of the Kantian moral system, as well as on the sense in which it might be taken to parallel, or otherwise be related to, Kant's theoretical system. (shrink)

L’article soutient l’hypothèse que, loin de récuser la question de l’obligation politique, Hegel présente cette notion à nouveaux frais en s’appuyant sur la notion de Gesinnung. À travers une lecture croisée dans les Principes de la philosophie du droit de l’introduction à l’éthicité et de certains paragraphes consacrés au droit étatique interne, l’article se penche sur les concepts de droiture et de patriotisme, ce dernier représentant la véritable disposition politique. Dans le sillage de l’interprétation institutionnaliste de Hegel, le propos de (...) cette étude est de mettre en relief les affinités entre la conception hégélienne et la théorie associative de l’obligation. (shrink)

This paper claims that Kant’s conception of culture provides a new means of understanding how the two parts of the Critique of Judgment fit together. Kant claims that culture is both the ‘ultimate purpose’ of nature and to be defined in terms of ‘art in general’ (of which the fine arts are a subtype). In the Critique of Teleological Judgment, culture, as the last empirically cognizable telos of nature, serves as the mediating link between nature and freedom, while in the (...) Critique of Aesthetic Judgment, the connection between art and morality passes through culture. In either case, Kant offers distinct, yet interdependent, arguments for how culture demonstrates the amenability of nature to its supersensible ground: the central question Kant claims in the Introduction that the work seeks to answer. Thus, not only does this account advance a concept essential to both parts of the work; it also demonstrates how the two parts can be conceived as complementary, with each supplementing the other to solve Kant’s central question. As such, understanding the Critique of Judgment in terms of culture enables us to see how the two parts of the work do not merely share points of similarity or common themes, but presuppose one another in order to understand how nature is amenable to freedom. (shrink)

While increasing attention has been paid in recent years to the relation between Foucault’s conception of critique and Kant’s, much controversy remains over whether Foucault’s most sustained early engagement with Kant, his dissertation on Kant’s Anthropology, should be read as a wholesale rejection of Kant’s views or as the source of Foucault’s late return to ethics and critique. In this paper, I propose a new reading of the dissertation, considering it alongside 1950s-era archival materials of which I advance the first (...) scholarly appraisal. I argue that Foucault manifests a fundamental ambivalence to Kantian anthropology, rejecting it in theoretical terms while embracing its practical (‘pragmatic’) conception of the subject. Furthermore, I take these texts to collectively evidence Foucault’s attempt to situate himself within the anthropological-critical tradition rather than extricating himself from it. If we interpret Foucault to reject this tradition’s appeal to an essentialized, theoretical conception of subjectivity, what remains of anthropology is its inherent practical reflexivity in structure. Thus, I situate Foucault’s conception of ethics as one’s relation to oneself in continuity with this tradition. (shrink)

The Opera of the National Theater in Belgrade was founded in 1920, but it is well known that opera performances were held long before its official opening. Despite the fact that this is the sole opera house in Belgrade, as well as the fact that it did not face any strong audience fluctuation, it is unusual that no one ever tried to investigate and profile its audience. During the last decades we were witnessing the popularization of the opera via various (...) medias, as well as development and extention of the music industry, which surely changed its social status. The aim of the investigation that is going to be presented is to discover if this social life of opera changed its audience and does it still consists of - according to stereotypes - elderly, high educated individuals of certain professions and high material standards, i.e. at which level the opera is present in the private and public sphere of their lives. Opera Narodnog pozorista u Beogradu osnovana je 1920. godine, ali je poznato da su operske predstave izvodjene i pre njenog zvanicnog osnivanja. Iako u radu nije nailazila na vecu fluktuaciju publike, a i dalje predstavlja jedinu opersku kucu u Beogradu, do sada nije bilo pokusaja da se naucno istrazi i profilise njena publika. Poslednjih decenija svedoci smo sve vece popularizacije operske muzike putem razlicitih medija, te razvijanjem i sirenjem muzicke industrije, sto dovodi i do promene njenog socijalnog statusa. Cilj ovog dela istrazivanja jeste da sazna da li je izmenjeni socijalni zivot opere izmenio i njenu publiku, da li nju - prema ustaljenim shvatanjima - i dalje pretezno cine visokoobrazovani, stariji pojedinci odredjenih zanimanja i visokog materijalnog standarda, odnosno koliko je opera zaista prisutna u privatnoj i javnoj sferi njihovih zivota. (shrink)

Against the background of a new Ten Commandments for the Polish business community a new course in business ethics is now being offered to students in the Faculty of Management and Economy of the Technical University of Gdańsk, ul. G. Narutowicza 11/12, 80‐952 Gdańsk, Poland. Dr Kinach‐Brzozowska, who introduced the course last year, describes its content and her students’needs and reactions.

Open Science policies encourage researchers to disclose a wide range of outputs from their work, thus codifying openness as a specific set of research practices and guidelines that can be interpreted and applied consistently across disciplines and geographical settings. In this paper, we argue that this “one-size-fits-all” view of openness sidesteps key questions about the forms, implications, and goals of openness for research practice. We propose instead to interpret openness as a dynamic and highly situated mode of valuing the research (...) process and its outputs, which encompasses economic as well as scientific, cultural, political, ethical, and social considerations. This interpretation creates a critical space for moving beyond the economic definitions of value embedded in the contemporary biosciences landscape and Open Science policies, and examining the diversity of interests and commitments that affect research practices in the life sciences. To illustrate these claims, we use three case studies that highlight the challenges surrounding decisions about how––and how best––to make things open. These cases, drawn from ethnographic engagement with Open Science debates and semistructured interviews carried out with UK-based biologists and bioinformaticians between 2013 and 2014, show how the enactment of openness reveals judgments about what constitutes a legitimate intellectual contribution, for whom, and with what implications. (shrink)

This Editorial introduces the thematic series on 'Toward a New Psychiatry: Philosophical and Ethical Issues in Classification, Diagnosis and Care' http://www.biomedcentral.com/series/newpsychiatry.

This multilevel meta-analysis examines whether emotional intelligence can be enhanced through training and identifies training effects’ determinants. We identified 24 studies containing 28 samples aiming at increasing individual-level EI among healthy adults. The results revealed a significant moderate standardized mean change between pre- and post-measurement for the main effect of EI training, and a stable pre- to follow-up effect. Additionally, the type of EI model, dimensions of the four branch model, length, and type of publication turned out to be significant (...) moderators. The results suggest that EI trainings should be considered effective interventions. (shrink)

Murdoch’s moral philosophy stresses the didactic theme of active self-improvement. To this end, she argues, we can work to amend the quality of our states of consciousness, and hence of our conduct. But while such work undoubtedly involves cognitive effort, Murdoch has much to say about the hazards of a specious or misguided intellectualism. By way of commentary on these views, the present paper suggests that Murdoch’s early apprenticeship in Marxist politics—and her subsequent rejection of Marxism—may have left a trace (...) both in the idea that ‘our states of consciousness differ in quality’ ; and in the specific, distinctively ‘idealist’ course proposed by her mature philosophy for the project of moral self-criticism. (shrink)

Partiendo de los aportes de una serie de estudios que desde una perspectiva socio-histórica han indagado en el proceso de construcción social de la categoría de desocupado, el artículo analiza el modo en que la falta de trabajo en personas válidas es problematizada en la obra de Karl Marx. Sostenemos que, si bien no hay en los desarrollos del pensador alemán una conceptualización del desocupado en su sentido moderno, sus contribuciones a través del estudio de la sobrepoblación relativa y del (...) lumpenproletariado dejaron sentadas ciertas bases para la puesta en forma de dicha categoría social y de intervención pública casi medio siglo más tarde.El artículo se plantea como una introducción a la pregunta por el papel que jugaron los primeros socialistas marxistas argentinos en la introducción de una perspectiva novedosa de interpretación de la falta de ocupación, forjada en diálogo con las ideas marxistas en circulación en el contexto internacional y en abierta disputa con las percepciones de la época. (shrink)

The use of big data to investigate the spread of infectious diseases or the impact of the built environment on human wellbeing goes beyond the realm of traditional approaches to epidemiology, and includes a large variety of data objects produced by research communities with different methods and goals. This paper addresses the conditions under which researchers link, search and interpret such diverse data by focusing on “data mash-ups”—that is the linking of data from epidemiology, biomedicine, climate and environmental science, which (...) is typically achieved by holding one or more basic parameters, such as geolocation, as invariant. We argue that this strategy works best when epidemiologists interpret localisation procedures through an idiographic perspective that recognises their context-dependence and supports a critical evaluation of the epistemic value of geolocation data whenever they are used for new research purposes. Approaching invariants as strategic constructs can foster data linkage and re-use, and support carefully-targeted predictions in ways that can meaningfully inform public health. At the same time, it explicitly signals the limitations in the scope and applicability of the original datasets incorporated into big data collections, and thus the situated nature of data linkage exercises and their predictive power. (shrink)

Knowledge-making practices in biology are being strongly affected by the availability of data on an unprecedented scale, the insistence on systemic approaches and growing reliance on bioinformatics and digital infrastructures. What role does theory play within data-intensive science, and what does that tell us about scientific theories in general? To answer these questions, I focus on Open Biomedical Ontologies, digital classification tools that have become crucial to sharing results across research contexts in the biological and biomedical sciences, and argue that (...) they constitute an example of classificatory theory. This form of theorizing emerges from classification practices in conjunction with experimental know-how and expresses the knowledge underpinning the analysis and interpretation of data disseminated online. (shrink)

The collection and dissemination of data on human and nonhuman organisms has become a central feature of 21st-century biology and has been endorsed by funding agencies in the United States and Europe as crucial to translating biological research into therapeutic and agricultural innovation. Large molecular data sets, often referred to as “big data,” are increasingly incorporated into digital databases, many of which are freely accessible online. These data have come to be seen as resources that play a key role in (...) mediating global market exchange, thus achieving a prominent social and economic status well beyond science itself. At the same time, calls to make all such data publicly and freely available have garnered strength and visibility, most prominently in the form of the Open Data movement. I discuss these developments by considering the conditions under which data journey across the communities and institutions implicated in globalized biology and biomedicine, and what this indicates about how Internet-based communication and the use of online databases affect scientific research and its role within contemporary society. (shrink)

I argue that Open Science as currently conceptualized and implemented does not take sufficient account of epistemic diversity within research. I use three case studies to exemplify how Open Science threatens to privilege some forms of inquiry over others, thus exasperating divides within and across systems of practice, and overlooking important sources and forms of epistemic diversity. Building on insights from pluralist philosophy, I then identify four aspects of diverse research practices that should serve as reference points for debates around (...) Open Science: (1) specificity to local conditions, (2) entrenchment within repertoires, (3) permeability to newcomers, and (4) demarcation strategies. (shrink)

An influential strand in philosophy of science claims that scientific paradigms can be understood as relativized a priori frameworks. Here, Kant’s constitutive a priori principles are no longer held to establish conditions of possibility for knowledge which are unchanging and universally true, but are restricted only to a given scientific domain. Yet it is unclear how exactly a relativized a priori can be construed as both stable and dynamical, establishing foundations for current scientific claims while simultaneously making intelligible the transition (...) to a subsequent framework. In this article, I show that important resources for this problem have been overlooked in Kant’s theory of reflective judgement in the third Critique. I argue that Kant accorded the task of formulating new scientific laws to reflective judgement, which is charged with forming new ‘universals’ that guide the experience of nature. I show that this is the very task attributed to the relativized a priori: the constitution of a given conceptual framework, not of the conditions for object-reference as such. I conclude that Kant’s considered conception of science encompasses the operations of both reflective and determining judgement. Relativizations of the a priori should follow Kant’s lead. (shrink)

All too often, the requirements for actionability and accountability of data infrastructures are conceptualised as incompatible and leading to a trade-off situation where increasing one will unavoidably decrease the other. Through a comparative analysis of two data infrastructures used to share genomic data about the SARS-COV-2 virus, we argue that making data actionable for knowledge development involves a commitment to ensuring that the data in question are representative of the phenomena being studied and accountable to data subjects and users. This (...) in turn presupposes that: (1) enough data are contributed by a wide and diverse set of relevant sources; (2) mechanisms of feedback and inclusion are set up to ensure that data contributors can participate data governance and interpretation, thereby helping to adequately contextualise data; and (3) accountability extends to the ways in which data infrastructures are run, financed and positioned vis-à-vis the communities they are meant to serve. Such a model of data sharing can only work on the understanding that data do not need to be easily accessible to be actionable; rather, actionability depends on the responsiveness and accountability of data infrastructures, and the efforts invested in ensuring open communication among contributors. (shrink)

This paper discusses what it means and what it takes to integrate data in order to acquire new knowledge about biological entities and processes. Maureen O’Malley and Orkun Soyer have pointed to the scientific work involved in data integration as important and distinct from the work required by other forms of integration, such as methodological and explanatory integration, which have been more successful in captivating the attention of philosophers of science. Here I explore what data integration involves in more detail (...) and with a focus on the role of data-sharing tools, like online databases, in facilitating this process; and I point to the philosophical implications of focusing on data as a unit of analysis. I then analyse three cases of data integration in the field of plant science, each of which highlights a different mode of integration: inter-level integration, which involves data documenting different features of the same species, aims to acquire an interdisciplinary understanding of organisms as complex wholes and is exemplified by research on Arabidopsis thaliana; cross-species integration, which involves data acquired on different species, aims to understand plant biology in all its different manifestations and is exemplified by research on Miscanthus giganteus; and translational integration, which involves data acquired from sources within as well as outside academia, aims at the provision of interventions to improve human health and is exemplified by research on Phytophtora ramorum. Recognising the differences between these efforts sheds light on the dynamics and diverse outcomes of data dissemination and integrative research; and the relations between the social and institutional roles of science, the development of data-sharing infrastructures and the production of scientific knowledge. (shrink)

Community databases have become crucial to the collection, ordering and retrieval of data gathered on model organisms, as well as to the ways in which these data are interpreted and used across a range of research contexts. This paper analyses the impact of community databases on research practices in model organism biology by focusing on the history and current use of four community databases: FlyBase, Mouse Genome Informatics, WormBase and The Arabidopsis Information Resource. We discuss the standards used by the (...) curators of these databases for what counts as reliable evidence, acceptable terminology, appropriate experimental set-ups and adequate materials (e.g., specimens). On the one hand, these choices are informed by the collaborative research ethos characterising most model organism communities. On the other hand, the deployment of these standards in databases reinforces this ethos and gives it concrete and precise instantiations by shaping the skills, practices, values and background knowledge required of the database users. We conclude that the increasing reliance on community databases as vehicles to circulate data is having a major impact on how researchers conduct and communicate their research, which affects how they understand the biology of model organisms and its relation to the biology of other species. (shrink)

Bogen and Woodward characterized data as embedded in the context in which they are produced (‘local’) and claims about phenomena as retaining their significance beyond that context (‘nonlocal’). This view does not fit sciences such as biology, which successfully disseminate data via packaging processes that include appropriate labels, vehicles, and human interventions. These processes enhance the evidential scope of data and ensure that claims about phenomena are understood in the same way across research communities. I conclude that the degree of (...) locality of both data and claims about phenomena varies depending on the packaging used to make them travel and on the research setting in which they are used. †To contact the author, please write to: ESRC Centre for Genomics in Society, University of Exeter, Byrne House, St. Germans Road, EX4 4PJ Exeter, United Kingdom; e‐mail: [email protected]. (shrink)

Given recent advances in technology, connectivity, and the popularity of social media platforms, recent literature has devoted great attention to problematic Facebook use. However, exploring the potential predictors of problematic social media use beyond Facebook use has become paramount given the increasing popularity of multiple alternative platforms. In this study, a sample of 584 social media users was recruited to complete an online survey assessing sociodemographic characteristics, patterns, and preferences of social media use, problematic social media use, social media use (...) motives, psychological well-being, self-esteem, and positive and negative affect. Results indicated that 6.68% of all respondents could be potentially classed as problematic users. Moreover, further analysis indicated that intrapersonal motive, negative affect, daily social media use, surveillance motive, and positive affect each predicted PSMU. These variables accounted for about 37% of the total variance in PSMU, with intrapersonal motive driving the greatest predictive contribution, over and above the effects of patterns of social media use and sociodemographic variables. These findings contribute to the increasing literature on PSMU. The results of this study are discussed in light of the existing literature on PSMU. (shrink)

Sabina Lovibond invites her readers to see how the "practical reason view of ethics" can survive challenges from within philosophy and from the antirationalist postmodern critique of reason. She elaborates and defends a modern practical-reason view of ethics by focusing on virtue or ideal states of character that involve sensitivity to the objective reasons circumstances bring into play. At the heart of her argument is the Aristotelian idea of the formation of character through upbringing; these ancient ideas can be (...) made contemporary if one understands them in a naturalized way. She then explores the implications that arise from the naturalization of the classical view, weaving into her theory ideas of Jacques Derrida and J. L. Austin. The book also discusses two modes of resistance to an existing ethical culture--one committed to the critical employment of shared norms of rationality, the other aspiring to a more radical attitude, grounded in hostility to the "universal." Lovibond tries to determine what may be correct in this second, admittedly paradoxical, tendency. This is a timely and valuable effort to connect the most advanced forms of thinking in the analytic tradition and in the Continental tradition, and to extend our understanding of the intimacies and resistances between these two prominent strands of contemporary philosophy. (shrink)

Arabidopsis is currently the most popular and well-researched model organism in plant biology. This paper documents this plant's rise to scientific fame by focusing on two interrelated aspects of Arabidopsis research. One is the extent to which the material features of the plant have constrained research directions and enabled scientific achievements. The other is the crucial role played by the international community of Arabidopsis researchers in making it possible to grow, distribute and use plant specimen that embody these material features. (...) I argue that at least part of the explosive development of this research community is due to its successful standardisation and to the subsequent use of Arabidopsis specimen as material models of plants. I conclude that model organisms have a double identity as both samples of nature and artifacts representing nature. It is the resulting ambivalence in their representational value that makes them attractive research tools for biologists. (shrink)

Dispositional mindfulness and emotion regulation are two psychological constructs closely interrelated, and both appear to improve with the long-term practice of mindfulness meditation. These constructs appear to be related to subcortical, prefrontal, and posterior brain areas involved in emotional processing, cognitive control, self-awareness, and mind wandering. However, no studies have yet discerned the neural basis of dispositional mindfulness that are minimally associated with emotion regulation. In the present study, we use a novel brain structural network analysis approach to study the (...) relationship between structural networks and dispositional mindfulness, measured with two different and widely used instruments [Mindfulness Attention Awareness Scale and Five Facet Mindfulness Questionnaire ], taking into account the effect of emotion regulation difficulties. We observed a number of different brain regions associated with the different scales and dimensions. The total score of FFMQ and MAAS overlap with the bilateral parahippocampal and fusiform gyri. Additionally, MAAS scores were related to the bilateral hippocampus and the FFMQ total score to the right insula and bilateral amygdala. These results indicate that, depending on the instrument used, the characteristics measured could differ and could also involve different brain systems. However, it seems that brain areas related to emotional reactivity and semantic processing are generally related to Dispositional or trait mindfulness, regardless of the instrument used. (shrink)

What is the best way to analyse abstraction in scientific modelling? I propose to focus on abstracting as an epistemic activity, which is achieved in different ways and for different purposes depending on the actual circumstances of modelling and the features of the models in question. This is in contrast to a more conventional use of the term ‘abstract’ as an attribute of models, which I characterise as black-boxing the ways in which abstraction is performed and to which epistemological advantage. (...) I exemplify my claims through a detailed reconstruction of the practices involved in creating two types of models of the flowering plant Arabidopsisthaliana, currently the best-known model organism in plant biology. This leads me to distinguish between two types of abstraction processes: the ‘material abstracting’ required in the production of Arabidopsis specimens and the ‘intellectual abstracting’ characterising the elaboration of visual models of Arabidopsis genomics. Reflecting on the differences between these types of abstracting helps to pin down the epistemic skills and research commitments used by researchers to produce each model, thus clarifying how models are handled by researchers and with which epistemological implications. (shrink)

How should actions to redress absolute human deprivation be framed? Current international coordinated actions on absolute poverty are framed by human rights or by goals such as the Millennium Development Goals. But appropriate, effective and sustained responses to needs require localized participation in the definition of those rights/goals/needs and in measures taken to redress them. Human rights or the MDGs do not seem necessarily to require such processes. For this reason some argue that no universal framework can describe economic, social, (...) or cultural rights. Yet to address absolute poverty purely from the local perspective still requires the identification and prioritization of capabilities or needs, and often requires actions by greater-than-local institutions, so in practical terms a framework is not rejected without cost. This paper argues that the identification and prioritisation of rights or MDGs can and should be done at an international level, but that they might be framed as capabilities, and that far greater attention need be given to the iterative specification of these rights, and to the ongoing protection of certain agency freedoms. The paper explores how Wiggins’ account of need can fruitfully inform the specification of needs claims. It also draws significantly on Sen’s work to identify the intrinsic importance of process and opportunity freedoms, and to identify how these can relate to universal priorities. (shrink)