Розкрито сутність поняття «рейтинг». Доведено значущість рейтингової оцінки для суб’єктів фінансового ринку, зокрема для страхових компаній, потенційних страхувальників, інвесторів та кредиторів.

Background: In the present study, we aimed to better investigate attention system profile of Parkinson's disease-Mild Cognitive Impairment patients and to determine if specific attentional deficits are associated with 123I-FP-CIT SPECT.Methods: A total of 44 de novo drug-naïve PD patients [ with normal cognition and 17 with MCI ], 23 MCI patients and 23 individuals with subjective cognitive impairment were recruited at the Clinical Neurology Unit of Santa Chiara hospital. They were assessed by a wide neuropsychological battery, including Visual Search (...) Test measuring selective attention. Performances among groups were compared by non-parametric tests. Further, Spearman's rank correlations were performed to explore the association between neuropsychological variables and 123I-FP-CIT SPECT data in PD subgroup.Results: PD-MCI patients performed worse on VST than patients with PD-NC, patients with MCI and individuals with SCI. The performance of PD-MCI patients on VST significantly correlated with caudate nucleus 123I-FP-CIT SPECT uptake, whereas a negative correlation between such test and 123I-FP-CIT SPECT uptake in the left putamen was found in PD-NC patients.Conclusions: We suggest that selective attention deficit might be a trigger of cognitive decay in de novo PD-MCI patients. The VST should be routinely used to detect attentional deficits in hospital clinical practice, in the light of its closely association with dopamine depletion of basal ganglia in mildly impaired PD patients. (shrink)

This book offers a critical introduction to the work of American philosopher D. G. Leahy (1937-2014). Leahy's fundamental thinking can be characterized as an absolute creativity in which all creating is 'live' -- a happening occurring now that manifests a supersaturated polyontological actuality that is essentially created by the logic that characterizes it. Leahy leaves behind the categorial presuppositions of modern thought, eclipsing both Cartesian and Hegelian subjectivities and introducing instead an essentially new form of thinking founded in a nondual (...) logic of creation. The new thinking delineates the absolute unicity of existence as a creative interactivity beyond all traditional dichotomies (such as one vs. many, unity vs. plurality, identity vs. change): a fully "digitized" actuality that is nothing but newness, which inherently implies nothing but change. Through this new form of thinking, change itself is revealed to be the very essence of reality and mind. Any reader looking for a quantum leap beyond the thrall of modern and postmodern fixations is invited to hear and apprehend this new thinking that refuses to be conditioned by paradigms, categories, species, genera, walls, bridges, boundaries, or abstractions: an essentially free thinking that embodies creative novelty itself. (shrink)

The acidity function is a thermodynamic quantitative measure of acid strength for non-aqueous and concentrated aqueous Brønsted acids, with acid strength being defined as the extent to which the acid protonates a base of known basicity. The acidity function, which was developed, both theoretically and experimentally, by Louis P. Hammett of Columbia University during the 1930s, has proven useful in the area of physical organic chemistry where it has been used to correlate rates of acid-catalyzed reactions and to quantitate the (...) acidity of superacids, acids with protonating abilities greater than pure sulfuric acid. All Brønsted acids can now be compared using a common measure. Karl Popper’s seminal idea of theory falsification does not apply here because of the many successful applications of the acidity function. Likewise, Thomas Kuhn’s idea of a paradigm shift does not apply here, even though the acidity function concept was revolutionary, because the acidity function is commensurate with classical concepts of acidity. (shrink)

Esperamos que este dossiê possibilite aos leitores uma reflexão sobre a problemática geral do governo das diferenças e dos corpos ingovernáveis, particularmente, que encontrem nesse conjunto de artigos algumas respostas para o enfrentamento da face obscura do biopoder no presente. Nossa expectativa também é a de que os eventuais impactos que esses corpos e suas alianças com a arte produzem na formação humana e em sua educação filosófica, tragam tanto à filosofia da educação quanto ao ensino de filosofia alguma oxigenação, (...) quem sabe, entusiasmando-nos a extrapolar os pensamentos, práticas de pesquisa e de ensino, que também são nossas. (shrink)

1 Os artigos reunidos em torno deste título, retratam a segunda parte das discussões ocorridas nas mesas redondas do VIII Simpósio Internacional em Educação e Filosofia, ocorrido de 27 a 29 de agosto de 2019, na UNESP, Campus de Marília/SP. Agradecemos a FAPESP, CAPES pelo apoio financeiro que nos possibilitou a apresentação dos resultados da proposta. O presente Dossiê tem como tema o governo das diferenças empreendidos pelas políticas estatais no neoliberalismo, as quais têm repercussão na educação. As reflexões aqui (...) desenvolvidas inserem-se, teoricamente, no debate filosófico contemporâneo da governamentalidade e da biopolítica. Particularmente, interessa debater em que medida os corpos ingovernáveis, denominados por vezes de desviantes ou anormais, estão compreendidos por essas formas de governo atuais ou lhes escapam, tanto singularmente quanto na qualidade de povo ou multidão, afrontando-as e agenciando modos outros de subjetivação, assim como potências da vida ou biopotências para tal. Para isso, esses artigos transitam entre a filosofia da diferença, a arte e a política, explicitando uma crítica contundente ao atual governo das diferenças e explorando cartografias do ingovernável na educação. A partir das diferenças mapeadas nos corpos singularizado, tais como os corpos das pessoas transgêneras, das deficientes, dos grupos afrodescendentes, dos povos indígenas ou quilombolas, este dossiê busca debater o lugar que ocupam no atual governo das diferenças na biopolítica neoliberal. Entende-se que a violência ou a exceção cometidas contra eles na atual conjuntura, quer seja nos contextos escolares ou em outros espaços sociais, assim como o potencial de resistência que apresentam, ao relatarem situações de abuso e de bullying, compõe uma ampla frente de desafios a serem problematizados pela filosofia da educação. É dessa expressividade e ethos que se ocuparão esses artigos, assim como a reflexão sobre e com eles, com vistas a dar visibilidade a esses modos de existência enquanto uma experiência singular e como um entretecido comum, associado às comunidades LGBTT+, afrodescendentes, deficientes, dentre outras, emergentes das suas lutas transversas em escolas e outras instituições. Apoiados em referências como as de Michel Foucault, Giorgio Agamben, Hannah Arendt, Jean Luc Nancy, Gilles Deleuze e Félix Guattari, dentre outros, assim, os artigos visibilizam esses corpos ingovernáveis, situando-os no jogo de subjugação e crítica empreendida pelas atuais formas de governamentalidade biopolítica – particularmente, na educação escolar. Ao mesmo tempo, como apresentados abaixo, eles abordam as possibilidades de sua biopotência, de sua capacidade de agenciar eticamente novas formas de inclusão pautadas na criação de novos modos de viver juntos e de vida comum. [...]. (shrink)

Resumo: Este artigo aborda a relevância da ocupação de si no processo de formação ética do sujeito e discute as possibilidades de seu uso para a educação. Recobra-se, para tanto, a genealogia da história da noção de cuidado, da parresia e da ética da amizade, retratadas no curso Hermenêutica do Sujeito ministrado por Michel Foucault. Objetiva-se problematizar, com isso, os aspectos moralizantes da pedagogia moderna e evidenciar uma dimensão ética da amizade e estética da existência, as quais foram abandonadas na (...) educação escolar. Buscam-se pensar em que medida essa dimensão pode ser recuperada como uma espécie de esquiva à racionalidade econômica e ao empreendimento de si, presentes nas práticas escolares contemporâneas, indicando algumas pistas sobre as questões éticas e políticas que incidem sobre as referidas práticas, no presente. Esse movimento possibilitará sinalizar para uma face psicagógica esboçada na antiguidade greco-romana, mas que fora abandonada em seu desenvolvimento moderno. Ao se enfatizar essa dimensão psicagógica e o papel que o outro ocupa, nessa relação, destaca-se a necessidade de certa ociosidade (Skholé) e encontro afetivo (Philia) do discípulo com o mestre, indagando-se sobre as adversidades tanto daquela vacância quanto dessa erótica, para se pensar nos desafios atuais da educação escolar. Palavras-chave: cuidado de si; formação ética do sujeito; educação escolar; Foucault. On the Foucauldian ethics of care, the subject and education: interpretive drifts 40 years after Hermeneutics of the Subject Abstract: This article analyzes the relevance of self-care in the subject's ethical formation process and discusses the possibilities of its use for education. For this purpose, we recover the genealogy of the history of the notion of care, parrhesia and the ethics of friendship, portrayed in the Hermeneutics of the Subject course taught by Michel Foucault. We aim to problematize with this the moralizing aspects of modern pedagogy and to highlight an ethical dimension of friendship and aesthetics of existence that were abandoned in school education. We seek to think to what extent this dimension can be recovered as a kind of evasion of economic rationality and the self-enterprise in contemporary school practices, indicating some clues about the ethical and political issues that affect these practices in the present. This movement will allow us to point to a psychogogical face outlined in Greco-Roman Antiquity, but which had been abandoned in its modern development. By emphasizing this psycagogical dimension and the role that the other occupies in this relationship, we highlight the need for a certain idleness (Skholé) and an affective encounter (Philia) of the disciple with the master, asking us about the adversities of both that vacancy and this erotic to think in the current challenges of school education. Keywords: self of care; ethical formation of the subject; schooling; Foucault. Sobre la ética foucauldiana del cuidado, el sujeto y la educación: derivas interpretativas 40 años después de la Hermenéutica del Sujeto Resumen: Este artículo analiza la relevancia de la ocupación de sí mismo en el proceso de formación ética del sujeto y discute las posibilidades de su uso para la educación. Para ello, recuperamos la genealogía de la historia de la noción de cuidado, la parresía y la ética de la amistad, retratada en el curso de Hermenéutica del Sujeto impartido por Michel Foucault. Pretendemos con eso problematizar los aspectos moralizantes de la pedagogía moderna y resaltar una dimensión ética de la amistad y estética de la existencia que fueron abandonadas en la educación escolar. Buscamos pensar en qué medida esta dimensión puede ser recuperada como una vía de escape a la racionalidad económica y el emprendimiento del yo en las prácticas escolares contemporáneas, indicando algunas pistas sobre las cuestiones éticas y políticas que afectan a estas prácticas en el presente. Este movimiento nos permitirá señalar un rostro psicagógico esbozado en la antigüedad grecorromana, pero que había sido abandonado en su desarrollo moderno. Al enfatizar esta dimensión psicogógica y el papel que el otro ocupa en esta relación, destacamos la necesidad de una cierta ociosidad (Skholé) y un encuentro afectivo (Philia) del discípulo con el maestro, preguntándonos por las adversidades de ambos esa vacancia y esta erótica para pensar en los desafíos actuales de la educación escolar. Palabras-clave: cuidado de sí; formación ética del sujeto; enseñanza; Foucault. Data de registro: 10/07/2022 Data de aceite: 13/12/2022. (shrink)

Resumo: Este artigo analisa o governo das diferenças em instituições como a escola e discute as condições de possibilidade de os corpos ingovernáveis resistirem às formas de dominação representadas pela biopolítica neoliberal. Para isso, recorre ao projeto foucaultiano e aos seus interlocutores com a finalidade de provocar no campo filosófico-educacional uma maior abertura para com o outro e as diferenças que encarnam. Vislumbramos com essa atitude ética e política agenciada pela relação com o ingovernável a possibilidade de resistir aos desdobramentos (...) fascistas da atual configuração da biopoder. Palavras-chave: Biopolítica. Governamentalidade. Diferença. Educação. Between the government of differences and the ungovernable of bodies: possibilities of resistance in education: This article examines the government of differences in institutions such as schools and discusses the conditions of possibility for ungovernablebodies to resist the forms of domination represented by neoliberal biopolitics. For this, it uses the Foucaultian project and its interlocutors in order to provoke in the philosophical-educational field a greater openness towards the other and the differences that they incarnate. We glimpse with this ethical and political attitude that the relationship with the ungovernable, the possibility of resisting the fascist developments of the current configuration of biopower. Keywords: Biopolitics. Governmentality. Difference. Education. Resumen: Este artículo examina el gobierno de las diferencias en instituciones como las escuelas y discute las condiciones de posibilidad para que los cuerpos ingobernables resistan las formas de dominación representadas por la biopolítica neoliberal. Para ello, utiliza el proyecto foucaultiano y sus interlocutores para provocar en el campo filosófico-educativo una mayor apertura hacia el otro y las diferencias que encarnan. Miramos con esta actitud ética y política, producida por la relación con lo ingobernable, la posibilidad de resistir a los desarrollos fascistas de la configuración actual del biopoder. Palabras clave: Biopolítica. Gubernamentalidad. Diferencia. Educación. (shrink)

Se è nel tempo e attraverso il movimento che partecipiamo alla vita, la morte ci nega per sempre questa possibilità. Nei sistemi viventi il tempo funge da organizzatore della situazione vitale dell’organismo. Il metabolismo e le funzioni vitali si compiono infatti attraverso lo scandire preciso e incalzante di ritmi biologici. Con la morte si verifica il disgregamento della nozione di tempo. Non si tratta più del tempo della vita che unisce, che coordina, che costruisce, che organizza. Il tempo della morte (...) è un tempo che distrugge, che disgrega, che disorienta, che sfilaccia l’unità della nostra esistenza nei frammenti non più ricomponibili di un puzzle. Ma la morte non è un fatto solo individuale, osserva lo psichiatra Eugène Minkowski in Le temps vécu. La morte, infatti, pone anche fine a tutte le relazioni di affetto, parentela e amicizia che ci hanno accompagnato durante la vita. Nell’articolo mostro come, a partire dalla riflessione di Minkowski, si possa parlare della morte da una duplice prospettiva di tempo vissuto: la morte come evento che impone una riflessione sulla finitudine umana, e come esperienza del vissuto individuale, oppure della morte patologica, la quale implica la morte del vissuto, ossia del contatto vitale costitutivo dell`esistenza umana. (shrink)

Mouvement et corporéité chez Patočka.Les origines aristotéliciennes du concept de mouvement ontologiquePatočka reconnaît dans le mouvement vital de l’existence humaine le fondement ontolotique de l’ouverture-au-monde et à l’Être entier comme totalité de ce qui est: par rapport à Heidegger par contre, Patočka entrevoit dans la corporéité une dimension ontologique fondamentale pour la donation même de l’existence actuelle. C’est dans ce sens que le mouvement de l’existence prend chez Patočka une dimension ontologique fondamentale: il représente, en dernière instance, un facteur déterminant (...) pour l’apparaître et la donation et le devenir actuel de l’existence, qui trouve précisément dans la corporéité le fondement ultime de sa manifestation.Le phénoménologue aveugle aperçoit chez Aristote la découverte très innovante (par rapport à la tradition philosophique qui l’avait précédé) d’un rapport dynamique et coessentiel entre l’Être et le mouvement: au cours du développement, je chercherai à montrer de quelle manière cette découverte assume pour Patočka une pertinence philosophique fondamentale, contribuant à la théorisation de l’idée de mouvement au sens ontologique. Il s’agira donc de montrer comment, à partir de l’analyse de la conception aristotélicienne du mouvement de sa relation avec la notion de substance,Patočka a élaboré sa propre idée de mouvement ontologique et de corporéité.Movement and Corporeality in Patočka.The Aristotelian Origins of the Concept of Ontological MovementPatočka recognized in the vital movement of human existence the ontological ground of the openness-to-the-world and to Being as a whole as the totality of thatwhich is. Unlike Heidegger, however, Patočka caught a glimpse in corporeality of a ontological dimension fundamental for the givenness of actual existence. It is in this sense that the movement of existence takes on a fundamental ontological dimension in Patočka: it represents, in a final analysis, a determining factor for the appearing and the givenness and the actual becoming of existence, which finds precisely in corporeality the ultimate ground of its manifestation.The blind phenomenologist glimpsed in Aristotle the very innovative discovery (with respect to the philosophical tradition that had preceded him) of a dynamic and coessential relationship between Being and movement. In the course of my argument, I will seek to show in what way this discovery assumes a fundamental philosophical pertinence for Patočka, contributing to the theorization of the idea of movement in an ontological sense. I will show how, following from the analysis of the Aristotelian conception of movement and of its relation with the notion of substance, Patočka elaborated his own idea of ontological movement and corporeality. (shrink)

Mouvement et corporéité chez Patočka.Les origines aristotéliciennes du concept de mouvement ontologiquePatočka reconnaît dans le mouvement vital de l’existence humaine le fondement ontolotique de l’ouverture-au-monde et à l’Être entier comme totalité de ce qui est: par rapport à Heidegger par contre, Patočka entrevoit dans la corporéité une dimension ontologique fondamentale pour la donation même de l’existence actuelle. C’est dans ce sens que le mouvement de l’existence prend chez Patočka une dimension ontologique fondamentale: il représente, en dernière instance, un facteur déterminant (...) pour l’apparaître et la donation et le devenir actuel de l’existence, qui trouve précisément dans la corporéité le fondement ultime de sa manifestation.Le phénoménologue aveugle aperçoit chez Aristote la découverte très innovante (par rapport à la tradition philosophique qui l’avait précédé) d’un rapport dynamique et coessentiel entre l’Être et le mouvement: au cours du développement, je chercherai à montrer de quelle manière cette découverte assume pour Patočka une pertinence philosophique fondamentale, contribuant à la théorisation de l’idée de mouvement au sens ontologique. Il s’agira donc de montrer comment, à partir de l’analyse de la conception aristotélicienne du mouvement de sa relation avec la notion de substance,Patočka a élaboré sa propre idée de mouvement ontologique et de corporéité.Movement and Corporeality in Patočka.The Aristotelian Origins of the Concept of Ontological MovementPatočka recognized in the vital movement of human existence the ontological ground of the openness-to-the-world and to Being as a whole as the totality of thatwhich is. Unlike Heidegger, however, Patočka caught a glimpse in corporeality of a ontological dimension fundamental for the givenness of actual existence. It is in this sense that the movement of existence takes on a fundamental ontological dimension in Patočka: it represents, in a final analysis, a determining factor for the appearing and the givenness and the actual becoming of existence, which finds precisely in corporeality the ultimate ground of its manifestation.The blind phenomenologist glimpsed in Aristotle the very innovative discovery (with respect to the philosophical tradition that had preceded him) of a dynamic and coessential relationship between Being and movement. In the course of my argument, I will seek to show in what way this discovery assumes a fundamental philosophical pertinence for Patočka, contributing to the theorization of the idea of movement in an ontological sense. I will show how, following from the analysis of the Aristotelian conception of movement and of its relation with the notion of substance, Patočka elaborated his own idea of ontological movement and corporeality. (shrink)

PENSAR A ÉTICA DA AMIZADE NA ESCOLA: A EMERGÊNCIA DA POÉTICA NA EDUCAÇÃO E UMA ATUALIZAÇÃO DA ESTÉTICA DA EXISTÊNCIA.

Although chemical phenomena are primarily associated with electrons in atoms, ions, and molecules, the masses, charges, spins, and other properties of the nuclei in these species contribute significantly as well. Isotopes, for instance, have proven invaluable in chemistry, in particular the elucidation of reaction mechanisms. Elements with unstable nuclei, for example carbon-14 undergoing beta decay, have enriched chemistry and many other scientific disciplines. The nuclei of all elements have a much more subtle and largely unknown effect on chemical phenomena. All (...) nuclei are innately chiral and, because electrons can penetrate nuclei, all atoms and molecules are likewise chiral. This article describes in considerable detail the discovery of chiral nuclei, how this unusual chirality may influence the chemical behavior of atoms and molecules, and how atomic chirality may have been responsible for the synthesis of optically active molecules in the pre-biotic world. (shrink)

A common approach in biosemiotics suggests that semiosis (any activity or process that involves signs) is a natural process embedded in evolution, which entails the production of meaningful processes. As Pattee has argued, a closer look at living systems shows that semiosis is closely related to a very specific and highly functional context of selected constraints. Symbolic control consists in 1) instituting a friction on the novelty, variability and randomness of life processes 2) allowing survival value at all levels of (...) biological organization and 3) enabling self-organization. Then it would be the network of semiotic controls to actually playing a pivotal role in biological organization and evolution. (shrink)

In this first paperback edition, a new introduction by Tom Burke establishes the ongoing importance of Sleeper's analysis of the integrity of Dewey's work and ...

Political liberals ask citizens not to appeal to certain considerations, including religious and philosophical convictions, in political deliberation. We argue that political liberals must include a demanding requirement of intellectual modesty in their ideal of citizenship in order to motivate this deliberative restraint. The requirement calls on each citizen to believe that the best reasoners disagree about the considerations that she is barred from appealing to. Along the way, we clarify how requirements of intellectual modesty relate to moral reasons for (...) deliberative restraint. And we argue against attempts to weaken our requirement of intellectual modesty by emphasizing those moral reasons. (shrink)

Locke is the first English philosopher to be considered in this series, and that fact of itself is worthy of attention. Philosophy, of course, like science, knows no frontiers and no national boundaries. Yet it is true to say that Locke’s contribution to philosophy is typically and peculiarly English. His moderation, his emphasis upon experience, his tolerant spirit of compromise, his dislike of mystical extravagance and of metaphysical speculation, even that elusive quality of his which people call his “common sense”, (...) are English traits. His very defects, illogicality leading to inconsistency and an awkward disorderliness of thought so abhorrent to the. (shrink)

The Nature of God explores a perennial problem in the philosophy of religion.

The notion of quality constitutes the title of a pressing philosophical problem. The issue of the location of the qualities of experience and reality leads to thematize the “clash” between the scientific and the manifest image, which also lays at the heart of the issues of naturalism and reductionism in the philosophy of mind. I argue that a transcendental version of the enactive approach constitutes a fruitful way to address these issues, thanks to its conception of the relation between subject (...) and object as dependent co-origination. In this way, the enactive view constitutes an alternative to both the internalism and the externalism about qualities, constituting a processual and relationist framework that can be fruitfully applied to the analysis of different ontological domains. In the conclusive section, I distinguish between an ontological and a metaphysical interpretation of this view, stressing the advantages of the former. (shrink)

Primary and methyl aliphatic halides and tosylates undergo substitution reactions with nucleophiles in one step by the classic S N 2 mechanism, which is characterized by second-order kinetics and inversion of configuration at the reaction center. Tertiary aliphatic halides and tosylates undergo substitution reactions with nucleophiles in two (or more) steps by the classic S N 1 mechanism, which is characterized by first-order kinetics and incomplete inversion of configuration at the reaction center due to the presence of ion pairs. When (...) the nucleophile is also the solvent, the substitution reaction is called a solvolysis, and both the S N 2 and S N 1 reactions now obey first-order kinetics. Schleyer and Bentley have provided solid, but not conclusive, evidence that secondary substrates undergo solvolysis by a merged mechanism, one that blends characteristics of both the S N 2 and S N 1 mechanisms. The following paper presents the history of their sustained pursuit of a merged mechanism and subsequent rebuttals to this claim. Several issues related to the philosophy and sociology of science are also discussed. (shrink)