Results for 'Nigel Holder'

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  1.  20
    Retinoic acid and development of the central nervous system.Malcolm Maden & Nigel Holder - 1992 - Bioessays 14 (7):431-438.
    We consider the evidence that RA†, the vitamin A metabolite, is involved in three fundamental aspects of the development of the CNS: (1) the stimulation of axon outgrowth in particular neuronal sub‐types; (2) the migration of the neural crest; and (3) the specification of rostrocaudal position in the developing CNS (forebrain, midbrain, hindbrain, spinal cord). The evidence we discuss involves RA‐induction of neurites in cell cultures and explants of neural tissue; the teratological effects of RA on the embryo's nervous system; (...)
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  2. Philosophy for the Rest of Cognitive Science.Nigel Stepp, Anthony Chemero & Michael T. Turvey - 2011 - Topics in Cognitive Science 3 (2):425-437.
    Cognitive science has always included multiple methodologies and theoretical commitments. The philosophy of cognitive science should embrace, or at least acknowledge, this diversity. Bechtel’s (2009a) proposed philosophy of cognitive science, however, applies only to representationalist and mechanist cognitive science, ignoring the substantial minority of dynamically oriented cognitive scientists. As an example of nonrepresentational, dynamical cognitive science, we describe strong anticipation as a model for circadian systems (Stepp & Turvey, 2009). We then propose a philosophy of science appropriate to nonrepresentational, dynamical (...)
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  3. Law as a moral idea.Nigel Simmonds - 2007 - New York: Oxford University Press.
    This book argues that the institutions of law, and the structures of legal thought, are to be understood by reference to a moral ideal of freedom or independence from the power of others. The moral value and justificatory force of law are not contingent upon circumstance, but intrinsic to its character. Doctrinal legal arguments are shaped by rival conceptions of the conditions for realization of the idea of law. In making these claims, the author rejects the viewpoint of much contemporary (...)
  4.  74
    Wanted: Philosophy of Management.Nigel Laurie & Christopher Cherry - 2001 - Philosophy of Management 1 (1):3-12.
    We attempt in this paper to define a new field of study for philosophy: philosophy of management. We briefly speculate why the interest some managers and management writers take in philosophy has been so little reciprocated and why it needs to be. Then we suggest the scope of this new branch of philosophy and how it relates to and overlaps with other branches. We summarise some key matters philosophers of management should concern themselves with and pursue one in some detail. (...)
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  5.  47
    Wittgenstein and the idea of a critical social theory: a critique of Giddens, Habermas, and Bhaskar.Nigel Pleasants - 1999 - New York: Routledge.
    This book uses the philosophy of Wittgenstein as a perspective from which to challenge the idea of a critical social theory, represented pre-eminently by Giddens, Habermas and Bhaskar.
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  6.  59
    How Essentialists Misunderstand Locke.Nigel Leary - 2009 - History of Philosophy Quarterly 26 (3):273-292.
    Talk of “essences” has, since Saul Kripke and Hilary Putnam, gained significant currency in contemporary philosophy. It is no longer unfashionable to talk about the essence of this or that (natural) kind, and as such we now find a variety of brands of essentialism on the market including B.D. Ellis’s scientific essentialism, David Oderberg’s real Essentialism, Alexander Bird’s dispositional essentialism, and the contemporary essentialism of Kripke and Putnam. -/- Almost all these brands of essentialism share a particular gloss on Locke’s (...)
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  7.  15
    A Mingled Yarn : Problematology and Science.Nigel Sanitt - 2007 - Revue Internationale de Philosophie 4 (4):435-449.
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  8.  19
    The Mary Poppins Effect.Nigel Sanitt - 1994 - Philosophy Now 9:11-12.
  9.  13
    A reverse gear for transcription‐coupled DNA repair? (Comment on DOI 10.1002/bies.201400106).Nigel Savery - 2015 - Bioessays 37 (1):4-4.
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  10.  18
    ?/? Barrel evolution and the modular assembly of enzymes: Emerging trends in the flavin oxidase/dehydrogenase family.Nigel S. Scrutton - 1994 - Bioessays 16 (2):115-122.
    Abstractα/β barrels have an ill‐defined origin. Evidence exists which favours their divergent evolution from a common ancestral barrel and convergent evolution to a stable fold. However, recent sequence and structural information for the flavin oxidase/dehydrogenase family of barrel enzymes indicate that sub‐families of α/β barrels have evolved divergently. The modular fusion of barrel domains with core structures from other gene families has also contributed to the evolution of related but catalytically distinct enzyme molecules within each sub‐family of the flavin oxidases/dehydrogenases. (...)
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  11.  21
    The Ancient Olympics.Nigel Spivey & University of Cambridge - 2004 - Oxford University Press.
    The word 'athletics' is derived from the Greek verb 'to struggle for a prize'. After reading this book, no one will see the Olympics as a graceful display of Greek beauty again, but as war by other means. Nigel Spivey paints a portrait of the Greek Olympics as they really were - fierce contests between bitter rivals, in which victors won kudos and rewards, and losers faced scorn and even assault. Victory was almost worth dying for, and a number (...)
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  12. Special Issue-Philosophy of the Teacher by Nigel Tubbs-Introduction.Nigel Tubbs - 2005 - Journal of Philosophy of Education 39 (2).
     
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  13.  15
    World ethics: the new agenda.Nigel Dower - 2007 - Edinburgh: Edinburgh University Press.
    World Ethics: The New Agenda identifies different ways of thinking about ethics, and of thinking ethically about international and global relations. It also considers several theories of world ethics in the context of issues such as war and peace, world poverty, the environment and the United Nations. The discussion is grounded in an awareness of the post-9/11 world in which we live and offers a more detailed exploration of the idea of global citizenship and a global or cosmopolitan ethic.
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  14.  6
    Saint Augustine and French classical thought.Nigel Abercrombie - 1938 - New York,: Russell & Russell.
    This work has been selected by scholars as being culturally important and is part of the knowledge base of civilization as we know it. This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and (...)
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  15.  28
    Relationships between the superior colliculus and hippocampus: Neural and behavioral considerations.Nigel Foreman & Robin Stevens - 1987 - Behavioral and Brain Sciences 10 (1):101-119.
    Theories of superior collicular and hippocampal function have remarkable similarities. Both structures have been repeatedly implicated in spatial and attentional behaviour and in inhibitory control of locomotion. Moreover, they share certain electrophysiological properties in their single unit responses and in the synchronous appearance and disappearance of slow wave activity. Both are phylogenetically old and the colliculus projects strongly to brainstem nuclei instrumental in the generation of theta rhythm in the hippocampal EECOn the other hand, close inspection of behavioural and electrophysiological (...)
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  16.  16
    An Oral History of the Ethics of Institutional Closure.Nigel Ingham & Dorothy Atkinson - 2013 - Ethics and Social Welfare 7 (3):241-256.
    This paper examines the ethical dimensions of the closure process of an English large long-stay institution for people with learning difficulties during the last quarter of the twentieth century. It does this primarily through an analysis of oral historical interview data stemming from those managers who implemented rundown. The paper illustrates the ways in which their testimonies indicate the presence of a morally infused dominant rhetoric, which was based upon the therapeutic benefits of closure, informed by the ideas of normalisation (...)
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  17.  94
    Computability, an introduction to recursive function theory.Nigel Cutland - 1980 - New York: Cambridge University Press.
    What can computers do in principle? What are their inherent theoretical limitations? These are questions to which computer scientists must address themselves. The theoretical framework which enables such questions to be answered has been developed over the last fifty years from the idea of a computable function: intuitively a function whose values can be calculated in an effective or automatic way. This book is an introduction to computability theory (or recursion theory as it is traditionally known to mathematicians). Dr Cutland (...)
  18.  90
    The Structure of Moral Revolutions.Nigel Pleasants - 2018 - Social Theory and Practice 44 (4):567-592.
    In the recent and not-too-distant past many of our parents, grandparents and forbears believed that a person’s skin colour and physiognomy, gender, or sexuality licensed them being regarded and treated in ways that are now widely recognised as blatantly unjust, disrespectful, cruel and brutal. But the nineteenth, twentieth, and twenty-first centuries have hosted a series of radical changes in attitudes, beliefs, behaviour and institutionalised practices with regard to the fundamental moral equality of what were once seen as different “kinds of (...)
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  19.  19
    Prioritisation for therapies based on a disorder’s severity: ethics and practicality.Nigel S. B. Rawson & John Adams - 2022 - Journal of Medical Ethics 48 (2):95-96.
    As the 20th century began, few effective therapies existed. This soon changed with major therapeutic discoveries turning the century into what has been called the golden age of therapeutics.1 The emphasis of most of these developments was on medicines for common disorders as they presented the greatest need. However, it also allowed pharmaceutical manufacturers to produce blockbuster drugs that provided a large return on investment. Rare disorders were overlooked because most are genetic in origin and scientific knowledge was lacking, making (...)
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  20.  19
    Combustion and Society: A Fire-Centred History of Energy Use.Nigel Clark & Kathryn Yusoff - 2014 - Theory, Culture and Society 31 (5):203-226.
    Fire is a force that links everyday human activities to some of the most powerful energetic movements of the Earth. Drawing together the energy-centred social theory of Georges Bataille, the fire-centred environmental history of Stephen Pyne, and the work of a number of ‘pyrotechnology’ scholars, the paper proposes that the generalized study of combustion is a key to contextualizing human energetic practices within a broader ‘economy’ of terrestrial and cosmic energy flows. We examine the relatively recent turn towards fossil-fuelled ‘internal (...)
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  21.  34
    Geosocial Formations and the Anthropocene.Nigel Clark & Kathryn Yusoff - 2017 - Theory, Culture and Society 34 (2-3):3-23.
    For at least two centuries most social thought has taken the earth to be the stable platform upon which dynamic social processes play out. Both climate change and the Anthropocene thesis – with their enfolding of dramatic geologic change into the space-time of social life – are now provoking social thinkers into closer engagement with earth science. After revisiting the decisive influence of the late 18th-century notion of geological formations on the idea of social formations, this introductory article turns to (...)
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  22.  3
    The limitations of theological truth: why Christians have the same Bible but different theologies.Nigel Brush - 2019 - Grand Rapids, MI: Kregel Publications, a division of Kregel.
    Theology is based on God's true and unchanging Word, but does it supply an unwavering foundation for spiritual certainties? Brush contends that it does not, because, like science, theology is a human discipline and subject to our limitations of knowledge, interpretation, and objectivity. In part one, Brush unpacks this contention, showing how Christians both past and present have arrived at conclusions that actually run counter to biblical teaching, and how these interpretive viewpoints have changed over time. In part two, he (...)
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  23. Wittgenstein, ethics and basic moral certainty.Nigel Pleasants - 2008 - Inquiry: An Interdisciplinary Journal of Philosophy 51 (3):241 – 267.
    Alice Crary claims that “the standard view of the bearing of Wittgenstein's philosophy on ethics” is dominated by “inviolability interpretations”, which often underlie conservative readings of Wittgenstein. Crary says that such interpretations are “especially marked in connection with On Certainty”, where Wittgenstein is represented as holding that “our linguistic practices are immune to rational criticism, or inviolable”. Crary's own conception of the bearing of Wittgenstein's philosophy on ethics, which I call the “intrinsically-ethical reading”, derives from the influential New Wittgenstein school (...)
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  24.  16
    Education in Hegel.Nigel Tubbs - 2008 - Continuum.
    Introduction -- Self and other : life and death -- Education in Hegel in the history of philosophy -- Fossil fuel culture -- Education in Hegel in Derrida -- Education in Hegel in Levinas -- I philosophy.
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  25. Are theories of imagery theories of imagination? An active perception approach to conscious mental content.Nigel J. T. Thomas - 1999 - Cognitive Science 23 (2):207-245.
    Can theories of mental imagery, conscious mental contents, developed within cognitive science throw light on the obscure (but culturally very significant) concept of imagination? Three extant views of mental imagery are considered: quasi‐pictorial, description, and perceptual activity theories. The first two face serious theoretical and empirical difficulties. The third is (for historically contingent reasons) little known, theoretically underdeveloped, and empirically untried, but has real explanatory potential. It rejects the “traditional” symbolic computational view of mental contents, but is compatible with recentsituated (...)
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  26.  18
    Politics of Strata.Nigel Clark - 2017 - Theory, Culture and Society 34 (2-3):211-231.
    Modern western political thought revolves around globality, focusing on the partitioning and the connecting up of the earth’s surface. But climate change and the Anthropocene thesis raise pressing questions about human interchange with the geological and temporal depths of the earth. Drawing on contemporary earth science and the geophilosophy of Deleuze and Guattari, this article explores how geological strata are emerging as provocations for political issue formation. The first section reviews the emergence – and eventual turn away from – concern (...)
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  27.  96
    Moral Argument Is Not Enough.Nigel Pleasants - 2010 - Philosophical Topics 38 (1):159-180.
    Slavery seems to us to be a paradigm of a morally wrong institutionalized practice. And yet for most of its millennia-long historical existence it was typically accepted as a natural, necessary, and inevitable feature of the social world. This widespread normative consensus was only challenged toward the end of the eighteenth century. Then, within a hundred years of the emergence of radical moral criticism of slavery, the existing practices had been dismantled and the institution itself “abolished.” How do we explain (...)
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  28.  62
    Philosophy of the teacher.Nigel Tubbs - 2005 - Oxford: Blackwell.
    This book offers a philosophical study of the teacher.
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  29.  14
    Perspectives on Anglo-Saxon Names.Nigel F. Barley - 1974 - Semiotica 11 (1):1-32.
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  30.  47
    Structural Aspects of the Anglo-Saxon Riddle.Nigel F. Barley - 1974 - Semiotica 10 (2).
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  31.  16
    Two Anglo-Saxon Sign Systems Compared.Nigel F. Barley - 1974 - Semiotica 12 (3).
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  32.  16
    The education act of 1870 as the start of the modern concept of the child.Nigel Middleton - 1970 - British Journal of Educational Studies 18 (2):166-179.
  33.  21
    Human Molecular Genetics Has Not Yet Contributed to Measurable Public Health Advances.Nigel Paneth & Sten H. Vermund - 2018 - Perspectives in Biology and Medicine 61 (4):537-549.
    The molecular genetic age can be said to have begun with the letter in Nature in 1953 by Watson and Crick, describing the helical structure of DNA. Some outstanding scientific work preceded that discovery, including especially the recognition by Chargaff of base-pair complementarity, but no discovery quite captured the imagination of the biomedical world as a few understated words by Watson and Crick in their famous one-page paper: "It has not escaped our notice that the specific pairing we have postulated (...)
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  34. Curiosity and the Aesthetics of Travel Writing 1770-1840: From an Antique Land.Nigel Leask - 2002 - Oxford University Press UK.
    The decades between 1770 and 1840 are rich in exotic accounts of the ruin-strewn landscapes of Ethiopia, Egypt, India, and Mexico. Yet it is a field which has been neglected by scholars and which - unjustifiably - remains outside the literary canon. In this pioneering book, Nigel Leask studies the Romantic obsession with these 'antique lands', drawing generously on a wide range of eighteenth- and nineteenth-century travel books, as well as on recent scholarship in literature, history, geography, and anthropology. (...)
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  35.  14
    Treating individuals according to evidence: why do primary care practitioners do what they do?Nigel Oswald & Hilarie Bateman - 2000 - Journal of Evaluation in Clinical Practice 6 (2):139-148.
  36.  44
    Gillick Competence: An Unnecessary Burden.Nigel Zimmermann - 2019 - The New Bioethics 25 (1):78-93.
    This study of the implications of Gillick competence argues it is an unnecessary burden with an unethical foundation. The ethics of adolescent medical decision-making is a fraught area for medical ethics because it deals with the threshold boundaries between childhood and adulthood and Gillick adds a burden upon children and adolescent patients that is unwarranted and through which damage is done to integral human relationships. In light of Gillick, it can be seen that the context of adolescent decision-making and childhood, (...)
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  37.  37
    The Impartial Spectator, amour-propre, and Consequences of the Secular Gaze: Rousseau's and Adam Smith's Responses to Mandeville.Nigel Joseph - 2011 - Lumen: Selected Proceedings From the Canadian Society for Eighteenth-Century Studies 30:33.
  38.  74
    Institutional wrongdoing and moral perception.Nigel Pleasants - 2008 - Journal of Social Philosophy 39 (1):96–115.
  39.  7
    Students as Lab Animals.Angela Roddey Holder - 2004 - American Journal of Bioethics 4 (1):37-38.
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  40.  31
    I am dynamite: an alternative anthropology of power.Nigel Rapport - 2003 - New York: Routledge.
    I Am Dynamite ignites an alternative theory of the self and will, wrapped up in a combustible assault upon scholarly convention. Asking why the real effort of constructing and living within an identity is so often overlooked, it examines the subjective experience of existing in the world, with the power to define and transform oneself. Considering the trials and triumphs of five very different modern subjects--Primo Levi, Ben Glaser, Stanley Spencer, Rachel Silberstein and Friedrich Nietzsche--Nigel Rapport asks: can consciousness (...)
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  41. Wittgenstein and basic moral certainty.Nigel Pleasants - 2009 - Philosophia 37 (4):669-679.
    In On Certainty, Wittgenstein’s reflections bring into view the phenomenon of basic certainty. He explores this phenomenon mostly in relation to our certainty with regard to empirical states of affairs. Drawing on these seminal observations and reflections, I extend the inquiry into what I call “basic moral certainty”, arguing that the latter plays the same kind of foundational role in our moral practices and judgements as basic empirical certainty does in our epistemic practices and judgements. I illustrate the nature and (...)
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  42.  88
    The Social Life of Bitcoin.Nigel Dodd - 2018 - Theory, Culture and Society 35 (3):35-56.
    This paper challenges the notion that Bitcoin is ‘trust-free’ money by highlighting the social practices, organizational structures and utopian ambitions that sustain it. At the paper's heart is the paradox that if Bitcoin succeeds in its own terms as an ideology, it will fail in practical terms as a form of money. The main reason for this is that the new currency is premised on the idea of money as a ‘thing’ that must be abstracted from social life in order (...)
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  43. Curiosity and the Aesthetics of Travel Writing 1770-1840: From an Antique Land.Nigel Leask - 2004 - Oxford University Press.
    The first book of its kind to study the Romantic obsession with the 'antique lands' of Ethiopia, Egypt, India, and Mexico, Curiosity and the Aesthetics of Travel Writing is an important contribution to the recent wave of interest in exotic travel writing. Drawing generously on both original texts and modern scholarship in literature, history, geography, and anthropology, it focuses on the unstable discourse of 'curiosity' to offer an important reformulation of the relations between literature, aesthetics, and colonialism in the period.
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  44.  12
    Re-educating thinking: philosophy, education, and pragmatism.Nigel Tubbs - 2023 - Journal of Philosophy of Education 57 (2):433-443.
    John Dewey stated that ‘[h]owever far apart philosophy and educational theory may later have become, in their beginnings they were strictly identical.' Dewey's ‘progressivism' in Democracy and Education rests on this communion. A self-reflective philosophical education by the community, about the community, for the community, would create the conditions for the advance of social justice. But new progressive ideas championing redistributive justice might appear to be in worryingly short supply. That is one reason, among many, why Philip Kitcher’s The Main (...)
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  45.  42
    Strength in numbers: High phenotypic variance in early Cambrian trilobites and its evolutionary implications.Nigel C. Hughes - 2007 - Bioessays 29 (11):1081-1084.
    Analysis of the degree of intraspecific morphological polymorphism during the evolutionary history of trilobites using an informatic approach1 provides striking evidence of a long‐suspected but previously unsubstantiated pattern: degrees of polymorphism are markedly higher in phylogenetically basal, stratigraphically early species. This unequivocal pattern prompts further exploration of the relationship between microevolutionary variance and macroevolutionary history. It demonstrates that the ‘traditional’ fossil record of skeletonized organisms can provide unique insight into questions of major evolutionary interest. BioEssays 29:1081–1084, 2007. © 2007 Wiley (...)
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  46.  30
    Trilobite body patterning and the evolution of arthropod tagmosis.Nigel C. Hughes - 2003 - Bioessays 25 (4):386-395.
    Preservation permitting patterns of developmental evolution can be reconstructed within long extinct clades, and the rich fossil record of trilobite ontogeny and phylogeny provides an unparalleled opportunity for doing so. Furthermore, knowledge of Hox gene expression patterns among living arthropods permit inferences about possible Hox gene deployment in trilobites. The trilobite anteroposterior body plan is consistent with recent suggestions that basal euarthropods had a relatively low degree of tagmosis among cephalic limbs, possibly related to overlapping expression domains of cephalic Hox (...)
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  47.  11
    High resolution measurement of dynamic indentation impact energy: a step towards the determination of indentation fracture resistance.Nigel M. Jennett & John Nunn - 2011 - Philosophical Magazine 91 (7-9):1200-1220.
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  48.  7
    Nano-mechanical testing in materials research and development.Nigel M. Jennett, Mathias Göken & Karsten Durst - 2011 - Philosophical Magazine 91 (7-9):1035-1036.
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  49.  14
    Not What It Says on the Tin: Ian Aitken (2006) Realist Film Theory and Cinema: The Nineteenth-century Lukácsian and Intuitionist Realist Traditions.Nigel Morris - 2007 - Film-Philosophy 11 (3):158-167.
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  50.  50
    Nothing is concealed: De-centring tacit knowledge and rules from social theory.Nigel Pleasants - 1996 - Journal for the Theory of Social Behaviour 26 (3):233–255.
    The concept of “tacit knowledge” as the means by which individuals interpret the “rules” of social interaction occupies a central role in all the major contemporary theories of action and social structure. The major reference point for social theorists is Wittgenstein's celebrated discussion of rule-following in the Philosophical Investigations. Focusing on Giddens' incorporation of tacit knowledge and rules into his “theory of structuration”, I argue that Wittgenstein's later work is steadfastly set against the “latent cognitivism” inherent in the idea of (...)
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