Unternehmen sind nicht nur wirtschaftliche, sondern auch politische Akteure. Vor allem aber sind sie entgegen verbreiteter Ansichten auch moralische Akteure, das heißt, sie sind grundsätzlich fähig, den moralischen Standpunkt einzunehmen, auch wenn sie dies in der Praxis selten tun. Daraus erwächst eine politische und moralische Verpflichtung: Auch für Unternehmen gelten die Menschenrechte als moralischer und rechtlicher Maßstab, daran müssen sich ihr Handeln und erst recht ihr Unterlassen messen lassen. Christian Neuhäuser zeigt mit beeindruckenden philosophischen Mitteln und anhand exponierter Beispiele unternehmerischen (...) Handelns, inwiefern und inwieweit Unternehmen moralisch zur Rechenschaft gezogen werden können. Dies hat weitreichende philosophische, ethische und nicht zuletzt politische Konsequenzen. (shrink)

Ontology development methodologies emphasise knowledge gathering from domain experts and documentary resources, and knowledge representation using an ontology language such as OWL or FOL. However, working ontologists are often surprised by how challenging and slow it can be to develop ontologies. Here, with a particular emphasis on the sorts of ontologies that are content-heavy and intended to be shared across a community of users (reference ontologies), we propose that a significant and heretofore under-emphasised contributor of challenges during ontology development is (...) the need to create, or bring about, consensus in the face of disagreement. For this reason reference ontology development cannot be automated, at least within the limitations of existing AI approaches. Further, for the same reason ontologists are required to have specific social-negotiating skills which are currently lacking in most technical curricula. (shrink)

Eine Ethik der Integration kann den aktuellen öffentlichen Diskurs über Migrationspolitik bereichern. Dazu ist es jedoch erforderlich, über die idealtheoretisch geprägten Debatten der politischen Theorie hinauszugehen und eine moralstrategische Perspektive einzunehmen. In diesem Beitrag werden einige Grundlagen einer pragmatischen Ethik der Integration geklärt, wobei drei Fragen im Zentrum stehen: Was sind die Kriterien einer gelingenden Integration von Immigrant_innen? Was sind die auf Integration bezogenen Pflichten und Rechte der Institutionen und Bürger_innen eines Landes, das Immigrant_innen aufnimmt? Was sind die auf Integration (...) bezogenen Rechte und Pflichten von Immigrant_innen? (shrink)

The goal of the 2010 Ontology Summit was to address the current shortage of persons with ontology expertise by developing a strategy for the education of ontologists. To achieve this goal we studied how ontologists are currently trained, the requirements identified by organizations that hire ontologists, and developments that might impact the training of ontologists in the future. We developed recommendations for the body of knowledge that should be taught and the skills that should be developed by future ontologists; these (...) recommendations are intended as guidelines for institutions and organizations that may consider establishing a program for training ontologists. Further, we recommend a number of specific actions for the community to pursue. (shrink)

The article reviews the recent debate about workplace democracy. It first presents and critically discusses arguments in favor of democratizing the firm that are based on the analogy with states, meaningful work, the avoidance of unjustified hierarchies, and beneficial effects on political democracy. The second part presents and critically discusses arguments against workplace democracy that are based on considerations of efficiency, the difficulties of a transition towards democratic firms, and liberal commitments such as the rights of employees and owners to (...) work for or invest in nondemocratic firms. The conclusion summarizes the debate and argues that experiments with democratic workplaces as what Erik Olin Wright calls “real utopias” could deliver new insights and thus move the discussion forward. (shrink)

New techniques for the genetic modification of organisms are creating new strategies for addressing persistent public health challenges. For example, the company Oxitec has conducted field trials internationally—and has attempted to conduct field trials in the United States—of a genetically modified mosquito that can be used to control dengue, Zika, and some other mosquito-borne diseases. In 2016, a report commissioned by the National Academies of Sciences, Engineering, and Medicine discussed the potential benefits and risks of another strategy, using gene drives. (...) Driving a desired genotype through a population of wild animals or insects could lead to irreversible genetic modification of an entire species. The NASEM report recommends community, stakeholder, and public engagement about potential uses of the technology, and it argues that the engagement should occur as research advances, well before gene drives are deployed. Yet what “engagement” means in practice is unclear. This article seeks clarity on this problem by offering a justification for community engagement and drawing out implications of this argument for the implementation and desired outcomes of community engagement. Community engagement is essential when it comes to research that would release genetically modified insects or animals into the environment. By contrast, obtaining informed consent from people who live near such a proposed field trial is neither necessary nor sufficient. Drawing on the epistemic and moral arguments for deliberative democracy, I propose two discrete mechanisms of community engagement: community advisory boards and deliberative forums, neither of which has been systematically incorporated into research governance. The proposed mechanisms would engender respect for persons who live near field trials, even when the results of deliberation override some individuals’ preferences. Community engagement foregrounds the community in our thinking about humans’ relationship to nature, and it implies that deciding to release genetically modified insects or animals into the wild ought to be a collective decision, not one made by product developers, policy-makers, private companies, research funders, or scientists alone. (shrink)

One of the tasks of ontology in information science is to support the classification of entities according to their kinds and qualities. We hold that to realize this task as far as entities such as material objects are concerned we need to distinguish four kinds of entities: substance particulars, quality particulars, substance universals, and quality universals. These form, so to speak, an ontological square. We present a formal theory of classification based on this idea, including both a semantics for the (...) theory and a provably sound axiomatization. (shrink)

What kind of world do we want to live in? It’s rare that we ask this question of ourselves, and even rarer that we get to do so with others. In Altered Inheritance: CRISPR and the Ethics of Human Genome Editing, Francoise Baylis encourages us to keep this question in the forefront of our minds as we think about whether, when, or how to edit the human genome. She is neither an “enthusiastic proponent nor a staunch opponent” of heritable human (...) genome editing. She is, however, very clear that the ethics of human genome editing is not the domain of scientists, ethicists, or elites. Her thesis is that all of us must think together about what our collective future should look like, and then consider whether and how... (shrink)

It is "time," writes Reto Winteler in the introduction to this book, to take Nietzsche "seriously, as the sui generis philosopher that he understood himself to be". Since at least the writing of Z, Nietzsche saw the transvaluation of all values as his life's great mission. He had long planned to compose a magnum opus on this topic, but following the completion of A, he suddenly considered it already accomplished. Winteler argues that although this decision has been acknowledged by the (...) scholarly community, no one has convincingly explained it. According to Winteler, it was not that Nietzsche failed to complete his work and his philosophical mission. Instead, he argues, Nietzsche... (shrink)

Review of: Kok-Chor Tan, Justice, Institutions and Luck.

In Germany, like in many other liberal countries, there is an extensive public discourse about freedom of speech being at risk. It will be insisted in this contribution that on the one hand, freedom of speech as a subjective right of basic law is not endangered. On the other hand, it should be acknowledged that in public discourse moralistic exaggerations are quite common. Against this background, the paper asks when different opinions are to be respected and at what point it (...) is permitted or even required to condemn them as immoral. The basic argument advanced here is that opinions should be respected as long as they are based in or at least supported by reasonable moral theories. Those opinions that do not have such a support can be labelled as properly immoral and criticized as such. (shrink)

In recent years, an interdisciplinary debate on the social and political role of business corporations has evolved. With this special issue, we would like to facilitate a comprehensive discussion of three questions that are especially pertinent in that debate: (1) How is the social and political agency of corporations to be understood? (2) How should the power of corporations be analyzed? (3) Under which conditions would the social and political roles of corporations be legitimate? In this introduction to the special (...) issue, we start with a short outline of the debate. In the next step, we provide an overview of the five contributions. We conclude by summarizing what can be learned from those contributions with respect to the three research questions. (shrink)

The following paper discusses Schiller’s interpretation of the German concept of Bildung. Bildung appears to be a central term in Germany’s culture, especially (but not limited to) the educational realm. As Bildung underwent massive transformations and has been re-interpreted multiple times throughout German history, this paper will start with a definitory exercise trying to organize the dynamics surrounding the term. Secondly, a two-fold historical context – firstly regarding the wider political and social dynamics of the time and secondly, a more (...) biographical approach focusing on Schiller – will be provided. These contextualizing efforts will be succeeded by elaborations on Schiller’s concept of Herzensbildung. The paper closes with a summary of key insights and further potential endeavors. (shrink)

It is now increasingly accepted that many existing biological and medical ontologies can be improved by adopting tools and methods that bring a greater degree of logical and ontological rigor. In this chapter we will focus on the merits of a logically sound approach to ontologies from a methodological point of view. As we shall see, one crucial feature of a logically sound approach is that we have clear and functional definitions of the relational expressions such as ‘is a’ and (...) ‘part of ’. (shrink)

The potential of large language models (LLM) has captured the imagination of the public and researchers alike. In contrast to previous generations of machine learning models, LLMs are general-purpose tools, which can communicate with humans. In particular, they are able to define terms and answer factual questions based on some internally represented knowledge. Thus, LLMs support functionalities that are closely related to ontologies. In this perspective article, I will discuss the consequences of the advent of LLMs for the field of (...) applied ontology. (shrink)

In this paper, I interrogate an ethical obligation to participate in genomics research on the basis of solidarity. I explore two different ways in which solidarity is used to motivate participation in genomics research: as an appeal to participate in genomic research because it cultivates solidarity and as an appeal to participate in genomic research because it expresses solidarity. I critique those appeals and draw lessons from them for how we ought to understand solidarity. The working definition of solidarity that (...) I defend is that solidarity involves recognizing another creature, person, or persons as, like ourselves, vulnerable to injustice and entails acting in ways that contribute to creating, reforming, and participating in institutions that are aimed at enhancing their flourishing. I argue that participating in genomics research is not an expression of solidarity. Participation in research may be praiseworthy, a “good thing to do,” but actually cultivating and expressing solidarity requires much more of us. (shrink)

Name der Zeitschrift: Deutsche Zeitschrift für Philosophie Jahrgang: 65 Heft: 4 Seiten: 786-791.

Recent reports and papers on chimeric research highlight the promise of chimeric models of human neuropsychiatric disorders to ameliorate human suffering due to autism spectrum disorders, depression, and schizophrenia. These calls, however, typically do not acknowledge, much less address, criticisms of model creation and validation, or concerns about scientific conduct more generally. The ethical justification for the use of nonhuman animals in research depends on the production of benefits to humans based on such research. But the assessment and production of (...) benefits are highly uncertain and rife with both practical and conceptual challenges. This essay provides a general framework for classifying the benefits of biomedical research and then focuses on two factors that directly impact—and threaten—the production of knowledge in research that models neuropsychiatric disorders. (shrink)

Non-human animal models of human diseases advance our knowledge of the genetic underpinnings of disease and lead to the development of novel therapies for humans. While mice are the most common model organisms, their usefulness is limited. Larger animals may provide more accurate and valuable disease models, but it has, until recently, been challenging to create large animal disease models. Genome editors, such as Clustered Randomised Interspersed Palindromic Repeat, meet some of these challenges and bring routine genome engineering of larger (...) animals and non-human primates well within reach. There is growing interest in creating NHP models of brain disorders such as autism, depression and Alzheimer’s, which are very difficult to model or study in other organisms, including humans. New treatments are desperately needed for this set of disorders. This paper is novel in asking: Insofar as NHPs are being considered for use as model organisms for brain disorders, can this be done ethically? The paper concludes that it cannot. Notwithstanding ongoing debate about NHPs’ moral status, animal welfare concerns, the availability of alternative methods of studying brain disorders and unmet expectations of benefit justify a stop on the creation of NHP model organisms to study brain disorders. The lure of using new genetic technologies combined with the promise of novel therapeutics presents a formidable challenge to those who call for slow, careful, and only necessary research involving NHPs. But researchers should not create macaques with social deficits or capuchin monkeys with memory deficits just because they can. (shrink)

In “Obligations of the Gift,” Lee argues that ethical thinking regarding return of genetic research results has been too narrowly focused on individual consent and participants’ “right to kn...

La volonté présente du christianisme de nouer un dialogue fraternel avec le judaïsme pose au premier le problème de reconnaître exactement l'identité du second, et d'interpréter correctement la judaïté de Jésus et la notion de « texte commun », présupposées à la base de cette rencontre. La religion de Jésus n'était pas encore ce qui allait devenir, après l’instauration du rabbinisme, la religion des juifs actuels, fondée sur la rédaction d'une Torah orale. Le judaïsme moderne et le christianisme sont à (...) la fois en rupture et en continuité herméneutique avec l'Ancien Testament, mais ils ne le lisent pas avec la même clé d'interprétation, le second le lisant à partir de son « accomplissement » dans le Nouveau, le premier en fonction de son « ouverture » à une autre nouveauté, qui sera le Talmud. L'idée d'un « patrimoine commun » aux juifs et aux chrétiens est née, dans un premier temps, de l'idéologie des Lumières, créatrice d’une culture commune, «judéo-chrétienne », au prix d'une lecture « scientifique » et désacralisante de la Bible. Dans un second temps, l'Holocauste, qui détournait les juifs, orthodoxes ou sionistes, de cet « héritage commun », conduisait inversement de nombreux chrétiens à le revendiquer, dans un aveu de culpabilité à l'égard de l'antisémitisme, mais aussi dans la méconnaissnce de la différence inéluctable du peuple juif. L'idéologie du « commun » peut être un facteur de fermeture là où elle ne se vérifie pas ou d'assimilation indue là où elle efface la singularité de l'un et de l'autre. On peut espérer du dialogue entre juifs et chrétiens qu’il suscite une authentique théologie de la rencontre.Today, the desire of Christianity to engage in a fraternal dialogue with Judaism poses the problem of encountering precisely the identity of the latter, and of interpreting correctly the Judaism of Jesus and the notion of « common text » which is presupposed at the basis of this encounter. The religion of Jesus was not yet that which it was to become after the installation of rabbinism, the religion of present day Jews, which was founded on the composition of an oral Torah. Modern Judaism and Christianity are, at the same time, in rupture and hermeneutic continuity with the Old Testament. But they do not read it with the same key of interpretation : Christianity’s reading sees its « accomplishment » in the New Testament, Judaism in function of its « opening » to another newness, which will be the Talmud. The idea of a « common patrimony » for Jews and Christians was born, in the first instance, of the ideology of the Enlightenment, creator of a common culture, « Judeo-Christian », at the price of a « scientific» and profane reading of the Bible. In a second stage, the Holocaust, which turned Orthodox and Zionist Jews away from this « common heritage », inversely led numerous Christians to vindicate it in an acknowledgment of culpability as regards anti-Semitism, but also in ignoring the ineluctable difference of the Jewish people. The ideology of the « common » can be a factor of closing dialogue when it is not verified or of undue assimilation when it wipes out the singularity of each one. One can hope for a dialogue between Jews and Christians that promotes an authentic theology of encounter. (shrink)

The micro blogging platform Twitter is actively used by millions of people. By using the geo tags of the messages sent a virtual landscape of online activity at a certain place is generated to visualize the interface between the real-world location and the virtual activity. These New City Landscapes (NCL) visualize the amount of activity as density surfaces with hills, peaks and valleys. Across a set of different cities from around the world the resulting landscape morphologies are compared and characterized (...) as types. This article focuses on temporal narratives and how they travel through the urban fabric via the virtual landscape in different cities around the world. The findings are discussed as cross comparisons according to activity in time and space. (shrink)

Logiker würden doch nur Tautologien und Trivialitäten produzieren. Mit dieser Kritik werden Logiker an philosophischen Instituten oft konfrontiert. Es wird ebenfalls eingewendet, daß mathematische Methoden in der Philosophie unangemessen seien, daß man durch die Verwendung dieser Methoden auf eine bestimmte philosophische Position festgelegt sei und daß der philosophische Gewinn den mit einem logischen Apparat verbundenen Aufwand nicht rechtfertige. In der Arbeit wird dargelegt, inwieweit diese vier Vorwürfe berechtigt sind und inwieweit sie auf Mißver- ständnissen beruhen. Dazu werden folgende Fragen beantwortet: (...) Was sind formale Sprachen und formale Systeme? Was ist die Aufgabe logischer Untersuchungen in der Philosophie? Sollten philosophische Texte formalisiert werden? Inwieweit ist Logik nützlich? Gibt es Beispiele für philosophisch fruchtbare logische Resultate? Legt Logik auf eine bestimmte Philosophie fest? Logik, so wird gezeigt, dient der Überprüfung philosophischer Argumente und als Medium zum Philosophieren. (shrink)

This article is the lead piece in a special report that presents the results of a bioethical investigation into chimeric research, which involves the insertion of human cells into nonhuman animals and nonhuman animal embryos, including into their brains. Rapid scientific developments in this field may advance knowledge and could lead to new therapies for humans. They also reveal the conceptual, ethical, and procedural limitations of existing ethics guidance for human‐nonhuman chimeric research. Led by bioethics researchers working closely with an (...) interdisciplinary work group, the investigation focused on generating conceptual clarity and identifying improvements to governance approaches, with the goal of helping scholars, funders, scientists, institutional leaders, and oversight bodies (embryonic stem cell research oversight [ESCRO] committees and institutional animal care and use committees [IACUCs]) deliver principled and trustworthy oversight of this area of science. The article, which focuses on human‐nonhuman animal chimeric research that is stem cell based, identifies key ethical issues in and offers ten recommendations regarding the ethics and oversight of this research. Turning from bioethics’ previous focus on human‐centered questions about the ethics of “humanization” and this research's potential impact on concepts like human dignity, this article emphasizes the importance of nonhuman animal welfare concerns in chimeric research and argues for less‐siloed governance and oversight and more‐comprehensive public communication. (shrink)

Finding solutions to complex health problems, such as obesity, violence, and climate change, will require radical changes in cross-disciplinary education, research, and practice. The fundamental determinants of health include many interrelated factors such as poverty, culture, education, environment, and government policies. However, traditional public health training has tended to focus more narrowly on diseases and risk factors, and has not adequately leveraged the rich contributions of sociology, anthropology, economics, geography, communication, political science, and other disciplines. Further, students are often not (...) sufficiently trained to work across sectors to translate research findings into effective, large-scale sustainable actions. During the past 2 decades, national and international organizations have called for more effective interdisciplinary, transdisciplinary, and translational approaches to graduate education. Although it has been difficult to work across traditional academic boundaries, some promising models draw on pedagogical theory and feature cross-disciplinary training focused on real-world problems, linkage between research, professional practice, community action, and cultivation of leadership skills. We describe the development the Doctor of Public Health program at the University of California, Berkeley, USA and its efforts to improve transdisciplinary and translational research education. We stress the need for international collaboration to improve educational approaches and better evaluate their impact. (shrink)

Is it a requirement of justice to democratize private companies? This question has received renewed attention in the wake of the financial crisis, as part of a larger debate about the role of companies in society. In this article, we discuss three principled arguments for workplace democracy and show that these arguments fail to establish that all workplaces ought to be democratized. We do, however, argue that republican-minded workers must have a fair opportunity to work in a democratic company. Under (...) current conditions, this means that a liberal order must actively promote workplace democracy. (shrink)

This study assessed self-reported health-related quality of life and psychological adjustment in 43 adolescents and young adults with congenital melanocytic nevi and examined associations with sociodemographic variables, characteristics of the CMN, perceived social reactions, and cognitive emotion regulation strategies. Outcome measures included the Pediatric Quality of Life Inventory™ 4.0 and the Strengths and Difficulties Questionnaire. Findings suggest impaired psychosocial health and psychological adjustment in youth with CMN compared to community norms. Impairments were associated with higher age of participants, lower socioeconomic (...) status, visibility of the skin lesion, perceived stigmatization, poorer perceived social support, and maladaptive cognitive emotion regulation strategies, but not with sex of participants, extent of the skin lesion, and surgical removal of the nevus. Implications for clinical practice and future research are discussed. (shrink)

Jeder Mensch hat eine Würde. Daraus scheint unmittelbar zu folgen, dass es kategorisch verboten ist, andere Menschen zu verachten. Aber so einfach ist das mit der Verachtung nicht. Denn schnell lassen sich Beispiele finden, bei denen es nicht offensichtlich falsch ist, wenn ein Mensch einen anderen Menschen verachtet. Wenn das Opfer eines Verbrechens den Täter verachtet, dann erscheint das durchaus angemessen, vielleicht sogar eine begrüßenswerte Reaktion zu sein. Dafür möchte ich jedenfalls auf der Grundlage der Würdetheorie von Ralf Stoecker argumentieren.

Der Schwerpunkt versammelt vier Aufsätze, die sich mit dem Verhältnis der philosophischen Begriffe „Verantwortung“ und „Pflicht“ beschäftigen. Obwohl diese beiden Begriffe einander sehr ähnlich sind und beide in der praktischen Philosophie eine wichtige Rolle spielen, gibt es kaum Untersuchungen zu der Frage, in welcher Beziehung beide Begriffe zueinander stehen. Drei Weisen, das Verhältnis zwischen Verantwortung und Pflicht zu bestimmen, scheinen naheliegend: 1. Die Begriffe sind synonym zu verstehen; 2. Verantwortung ist der zentrale Begriff; 3. Pflicht ist der zentrale Begriff. In (...) dieser Einleitung werden diese drei möglichen Positionen skizziert und die vier Texte des Schwerpunktes vorgestellt. (shrink)

Historically contingent concepts like human dignity do not allow for the exclusion of historical considerations from their analysis. In order to demonstrate this, the present essay compares the positions of Hans-Johann Glock and Hans Blumenberg. While Glock deals with the convergence of analytic philosophy and historical approaches, Blumenberg highlights the importance of historical constants. Glock argues for a pragmatic historicism according to which historical inquiry is useful but not indispensable. Through comparison with Blumenberg’s position, it is shown that this assessment (...) is incomplete. It is then argued that there is a more fitting position, according to which historical inquiry is essential for some, though not all, concepts. This position is illustrated by the concept of human dignity, which cannot be adequately grasped without reference to its genesis. Blumenberg’s approach can thus help precisely where the connection between analytical philosophy and historical investigation in Glock’s sense falters. (shrink)