A dorsalization mechanism is a good candidate for the evolutionary origin of the isocortex, producing a radial and tangential expansion of the dorsal pallium (and perhaps other structures that acquired a cortical phenotype). Evidence suggests that a large part of the dorsal ventricular ridge (DVR) of reptiles and birds derives from the embryonic ventral pallium, whereas the isocortex possibly derives mostly from the dorsal pallium. In early mammals, the development of olfactory-hippocampal associative networks may have been pivotal in facilitating the (...) selection of a larger and more complex dorsal pallium which received both collothalamic and lemnothalamic sensory information. Finally, although it is not clear exactly when mammalian brain expansion began, fossil evidence indicates that this was a late event in mammaliaform evolution. (shrink)

When visual attention is directed away from a stimulus, neural processing is weak and strength and precision of sensory data decreases. From a computational perspective, in such situations observers should give more weight to prior expectations in order to behave optimally during a discrimination task. Here we test a signal detection theoretic model that counter-intuitively predicts subjects will do just the opposite in a discrimination task with two stimuli, one attended and one unattended: when subjects are probed to discriminate the (...) unattended stimulus, they rely less on prior information about the probed stimulus’ identity. The model is in part inspired by recent findings that attention reduces trial-by-trial variability of the neuronal population response and that they use a common criterion for attended and unattended trials. In five different visual discrimination experiments, when attention was directed away from the target stimulus, subjects did not adjust their response bias in reaction to a change in stimulus presentation frequency despite being fully informed and despite the presence of performance feedback and monetary and social incentives. This indicates that subjects did not rely more on the priors under conditions of inattention as would be predicted by a Bayes-optimal observer model. These results inform and constrain future models of Bayesian inference in the human brain. (shrink)

Barzykowski and Moulin suggest that déjà vu and involuntary autobiographical memories recruit similar retrieval processes. Here, we invite the authors to clarify three issues: (1) What mechanism prevents déjà vu to happen more frequently? (2) What is the role of semantic cues in involuntary autobiographical retrieval? and (3) How déjà vu relates to non-believed memories?

The isocortex is a distinctive feature of mammalian brains, which has no clear counterpart in the cerebral hemispheres of other amniotes. This paper speculates on the evolutionary processes giving rise to the isocortex. As a first step, we intend to identify what structure may be ancestral to the isocortex in the reptilian brain. Then, it is necessary to account for the transformations (developmental, connectional, and functional) of this ancestral structure, which resulted in the origin of the isocortex. One long-held (...) perspective argues that part of the isocortex derives from the ventral pallium of reptiles, whereas another view proposes that the isocortex originated mostly from the dorsal pallium. We consider that, at this point, evidence tends to favor correspondence of the isocortex with the dorsal cortex of reptiles. In any case, the isocortex may have originated partly as a consequence of an overall “dorsalizing” effect (that is, an expansion of the territories expressing dorsal-specific genes) during pallial development. Furthermore, expansion of the dorsal pallium may have been driven by selective pressures favoring the development of associative networks between the dorsal cortex, the olfactory cortex, and the hippocampus, which participated in spatial or episodic memory in the early mammals. In this context, sensory projections that in reptiles end in the ventral pallium, are observed to terminate in the isocortex (dorsal pallium) of mammals, perhaps owing to their participation in these associative networks. Key Words: basolateral amygdala; claustrum; Emx-1; endopiriform nucleus; dorsal cortex; dorsal ventricular ridge; hippocampus; homology; olfactory cortex; Pax-6; ventral pallium. (shrink)

An overview of the latest interdisciplinary research on human morality, capturing moral sensibility as a sophisticated integration of cognitive, emotional, and motivational mechanisms. Over the past decade, an explosion of empirical research in a variety of fields has allowed us to understand human moral sensibility as a sophisticated integration of cognitive, emotional, and motivational mechanisms shaped through evolution, development, and culture. Evolutionary biologists have shown that moral cognition evolved to aid cooperation; developmental psychologists have demonstrated that the (...) elements that underpin morality are in place much earlier than we thought; and social neuroscientists have begun to map brain circuits implicated in moral decision making. This volume offers an overview of current research on the moral brain, examining the topic from disciplinary perspectives that range from anthropology and neurophilosophy to justice and law. The contributors address the evolution of morality, considering precursors of human morality in other species as well as uniquely human adaptations. They examine motivations for morality, exploring the roles of passion, extreme sacrifice, and cooperation. They go on to consider the development of morality, from infancy to adolescence; findings on neurobiological mechanisms of moral cognition; psychopathic immorality; and the implications for justice and law of a more biological understanding of morality. These new findings may challenge our intuitions about society and justice, but they may also lead to more a humane and flexible legal system. Contributors Scott Atran, Abigail A. Baird, Nicolas Baumard, Sarah Brosnan, Jason M. Cowell, Molly J. Crockett, Ricardo de Oliveira-Souza, Andrew W. Delton, Mark R. Dadds, Jean Decety, Jeremy Ginges, Andrea L. Glenn, Joshua D. Greene, J. Kiley Hamlin, David J. Hawes, Jillian Jordan, Max M. Krasnow, Ayelet Lahat, Jorge Moll, Caroline Moul, Thomas Nadelhoffer, Alexander Peysakhovich, Laurent Prétôt, Jesse Prinz, David G. Rand, Rheanna J. Remmel, Emma Roellke, Regina A. Rini, Joshua Rottman, Mark Sheskin, Thalia Wheatley, Liane Young, Roland Zahn. (shrink)

In the last fifteen years, there has been significant interest in studying the brain structures involved in moral judgments using novel techniques from neuroscience such as functional magnetic resonance imaging. Many people, including a number of philosophers, believe that results from neuroscience have the potential to settle seemingly intractable debates concerning the nature, practice, and reliability of moral judgments. This has led to a flurry of scientific and philosophical activities, resulting in the rapid growth of the new (...) field of moral neuroscience. There is now a vast array of ongoing scientific research devoted towards understanding the neural correlates of moral judgments, accompanied by a large philosophical literature aimed at interpreting and examining the methodology and the results of this research. This is the first volume to take stock of fifteen years of research of this fast-growing field of moral neuroscience and to recommend future directions for research. It features the most up-to-date research in this area, and it presents a wide variety of perspectives on this topic. (shrink)

Scientists no longer accept the existence of a distinct moral organ as phrenologists once did. A generation of young neurologists is using advanced technological medical equipment to unravel specific brain processes enabling moral cognition. In addition, evolutionary psychologists have formulated hypotheses about the origins and nature of our moral architecture. Little by little, the concept of a ‘moral brain’ is reinstated. As the crossover between disciplines focusing on moral cognition was rather limited up (...) to now, this book aims at filling the gap. Which evolutionary biological hypotheses provide a useful framework for starting new neurological research? How can brain imaging be used to corroborate hypotheses concerning the evolutionary background of our species? In this reader, a broad range of prominent scientists and philosophers shed their expert view on the current accomplishments and future challenges in the field of moral cognition and assess how cooperation between neurology and evolutionary psychology can boost research into the field of the moral brain. (shrink)

Technology is evolving at a rate faster than human evolution, especially human moral evolution. There are those who claim that we must morally bioenhance the human due to existential threats (such as climate change and the looming possibility of cognitive enhancement) and due to the fact that the human animal has a weak moral will. To address these existential threats, we must design human morality into human beings technologically. By moral bioenhancement, these authors mean that we must (...) intervene technologically in the biology of the human animal in order to get it to behave morally to address these existential threats. I will bring the idea of moral bioenhancement into conversation with two philosophers of technology. Bernard Stiegler has argued that technology and culture, and thus technology and human beings, have always evolved hand in hand. Peter-Paul Verbeek notes that we have always designed morality into technology, and thus he sees technology as mediating human morality. When we offload human intentionality onto technology, Verbeek argues, technological objects and systems participate in shaping the moral subjectivity of the human actor. I will show that modern technological bioenhancement obliterates human being. Whereas in the past, human culture was handed from generation to generation through the mediation of technology, in the modern era, the human becomes the raw material upon which a technological will (imperative) rides. (shrink)

: Moral cognition research has in part been taken to be a problem for moral sentimentalists, who claim that emotions are sensitive to moral information. In particular, Joshua Greene can be understood to provide an argument against moral sentimentalism on the basis of neuropsychological evidence. In his argument he claims that emotions are an unreliable source of moral insight. However, the argument boils down to circular claims: Rationalistic factors are assumed to be the only morally (...) relevant factors; Emotions are not sensitive to these factors; Thus, Moral Sentimentalism is false, because only rationalistic factors are justified. While this circularity makes so-called sourcing-arguments fallacious if applied against moral sentimentalism, moral cognition research has much to contribute. Indeed, moral cognition research will be instrumental for clarifying the sentimentalist position, shedding light on the mental mechanics underlying emotional moral processing. After all, evidence from moral cognition points to substantial involvement of affective processes in human moral cognizing and their embodied nature; thus, challenging long held beliefs about morality. Keywords : Moral Cognition; Moral Sentimentalism; Emotions; Embodied Cognition; Moral Brain Emozioni, Esperimenti e il cervello morale. L’errore degli argomenti basati sulla cognizione morale contro il sentimentalismo morale Riassunto: Si è spesso ritenuto che la ricerca nell’ambito della cognizione morale costituisse, almeno in parte, un problema per il sentimentalismo morale, il quale sostiene che le emozioni sono sensibili all’informazione morale. In particolare, si può pensare che Joshua Greene abbia portato un argomento contro il sentimentalismo morale basato su evidenza neuropsicologica. Secondo il suo argomento le emozioni non costituiscono una fonte affidabile di comprensione morale. E tuttavia questo argomento fa leva su una circolarità: gli unici fattori qualificati come moralmente rilevanti sono quelli razionali; le emozioni non sono sensibili a questi fattori; pertanto, considerato che solo i fattori razionali sono giustificati, il sentimentalismo morale è falso. Tale circolarità rende fallaci i cosiddetti argomenti sorgente, laddove questi siano applicati al sentimentalismo morale. Al contempo, la ricerca sulla cognizione morale ha molto da dire su questo argomento perché può contribuire a chiarire la posizione sentimentalista, gettando luce sulla meccanica mentale sottostante i processi morali che fanno leva su emozioni. Anzi questa prospettiva di ricerca evidenzia che i processi di carattere affettivo sono coinvolti in maniera sostanziale nella cognizione morale umana e hanno una natura incarnata; in questo modo essa mette in discussione convinzioni di vecchia data sulla morale. Parole chiave : Cognizione morale; Sentimentalismo morale; Emozioni; Cognizione incarnata; Cervello morale. (shrink)

This article probes the evolutionary origins ofmoral capacities and moral agency. From thisit develops a theory of the guidancesystem of higher mind (GSHM). The GSHM is ageneral model of intelligence whereby moralfunctioning is integrated with cognitive,affective, and conative functioning, resultingin a flow of information between eight brainlevels functioning as an evaluative unitbetween stimulus and response.The foundation of this view of morality and ofcaring behavior is Charles Darwin's theory,largely ignored until recently, of thegrounding of morality in sexual instincts whichlater expand (...) into parental love. Also, PaulMacLean made these same connections in hisdevelopment of the triune brain theory, whichwas founded on observations of both sexual andaffectionate responses from stimulation oflimbic and paleocortical areas (that is, notthe most primitive areas) of monkey brains. This article relates the revolutionary areas ofDarwin and of MacLean together for the firsttime in an way intended to be accessible to arange of social and natural scientists. TheGSHM builds on and expands both of their workto develop a theory of the processing withinour brains of information screened by asequence of systems, social, future, moral,developmental, and managerial ``sensitivities.''Darwin's and MacLean's observations and theGSHM theory developed here argue against theold strict distinction between ``lower''emotional processes and ``higher'' rationalprocesses. In fact, MacLean, Karl Pribram, andothers have found that emotional responses areclosely tied to reason through the functions ofthe prefrontal cortex. Prefrontal function isclosely related to the development of moralsensibility and judgment. In particular, it isthe connections between prefrontal cortex andother brain areas that allow us to makedeliberate choices to be or not to be caring. These same connections allow us to learnculturally sensitive signals for when torelease or inhibit our cooperative oraggressive tendencies (both of which can beelicited by sexual displays in monkeys as wellas humans). These are closely tied to thesocial instinct in animals, and to thesocialization that children receive from theirparents (whom the clinical psychologist AlanSchore has described as providing a ``substituteprefrontal cortex'' for their very youngchildren). Higher levels of the GSHM modelsuch capabilities as thinking beyond thecurrent social situation to ``what could be'' anddialectical synthesis of apparent opposites,which are what allow humans the freedom todesign social realities to fit our moralsensibilities. (shrink)

An argument that moral functioning is immeasurably complex, mediated by biology but not determined by it. Throughout history, humanity has been seen as being in need of improvement, most pressingly in need of moral improvement. Today, in what has been called the beginnings of “the golden age of neuroscience,” laboratory findings claim to offer insights into how the brain “does” morality, even suggesting that it is possible to make people more moral by manipulating their biology. Can (...) “moral bioenhancement”—using technological or pharmaceutical means to boost the morally desirable and remove the morally problematic—bring about a morally improved humanity? In The Myth of the Moral Brain, Harris Wiseman argues that moral functioning is immeasurably complex, mediated by biology but not determined by it. Morality cannot be engineered; there is no such thing as a “moral brain.” Wiseman takes a distinctively interdisciplinary approach, drawing on insights from philosophy, biology, theology, and clinical psychology. He considers philosophical rationales for moral enhancement, and the practical realities they come up against; recent empirical work, including studies of the cognitive and behavioral effects of oxytocin, serotonin, and dopamine; and traditional moral education, in particular the influence of religious thought, belief, and practice. Arguing that morality involves many interacting elements, Wiseman proposes an integrated bio-psycho-social approach to the consideration of moral enhancement. Such an approach would show that, by virtue of their sheer numbers, social and environmental factors are more important in shaping moral functioning than the neurobiological factors with which they are interwoven. (shrink)

Matthew Liao is to be commended for editing Moral Brains, a fine collection showcasing truly 12 excellent chapters by, among others, James Woodward, Molly Crocket, and Jana Schaich 13 Borg. In addition to Liao’s detailed, fair-minded, and comprehensive introduction, the book 14 has fourteen chapters. Of these, one is a reprint (Joshua Greene ch. 4), one a re-articulation of 15 previously published arguments (Walter Sinnott-Armstrong ch. 14), and one a literature review 16 (Oliveira-Souza, Zahn, and Moll ch. 9). The (...) rest are original contributions to the rapidly 17 developing field of neuroethics. (shrink)

The empirical investigations over the past fifteen years of evolutionary biologists and cognitive scientists have demonstrated the accessibility and power of the human brain. Whatever moral concepts used to acknowledge the normative appraisals of human conduct are now explained through neurological hardwiring. This essay outlines some of the main views of proponents, but especially Marc Hauser, and I argue that it does not render the end of morals. It does provide an opportunity to view the facts of how (...) the brain functions but this essay finds a large domain of valuing unable to be justified by these new scientific challenges. (shrink)

I draw on neurobiological evidence to defend the rationalist thesis that moral judgments are essentially dependent on reasoning, not emotions (conceived as distinct from inference). The neuroscience reveals that moral cognition arises from domain-general capacities in the brain for inferring, in particular, the consequences of an agent’s action, the agent’s intent, and the rules or norms relevant to the context. Although these capacities entangle inference and affect, blurring the reason/emotion dichotomy doesn’t preferentially support sentimentalism. The argument requires (...) careful consideration of the empirical evidence (from neuroimaging to psychopathology) and philosophical analysis of the commitments of rationalism versus sentimentalism in ethics. (shrink)

Matthew Liao’s edited collection Moral Brains: The Neuroscience of Morality covers a wide range of issues in moral psychology. The collection should be of interest to philosophers, psychologist, and neuroscientists alike, particularly those interested in the relation between these disciplines. I give an overview of the content and major themes of the volume and draw some important lessons about the connection between moral neuroscience and normative ethics. In particular, I argue that moving beyond some of the dichotomies (...) implicit in some of the debates advanced in the book makes the neuroscience of moral judgment much more useful in advancing normative ethics. (shrink)

In the theoretical literature on moral responsibility, one sometimes comes across cases of manipulated agents. In cases of this type, the agent is a victim of wholesale manipulation, involving the implantation of various pro-attitudes (desires, values, etc.) along with the deletion of competing pro-attitudes. As a result of this manipulation, the agent ends up performing some action unlike any that she would have performed were it not for the manipulation. These sorts of cases are sometimes thought to motivate historical (...) views of responsibility, on which the agent’s past is relevant to whether she is responsible for a specific action. In a recent paper, Daniel Sharp and David Wasserman bring these theoretical discussions on moral responsibility to bear on practical issues regarding neurological modifications of individuals. After proposing and arguing for a historical view, Sharp and Wasserman offer some insight into how such a view may help us in determining the responsibility of subjects who have undergone Deep Brain Stimulation. This paper aims to join this discussion, by arguing that the correct historical view to be applied will also appeal to the agent’s control over her mental life and the fact that this was bypassed. I conclude with some brief comments on the practical implications of such a historical view. (shrink)

Brain organoid research raises ethical challenges not seen in other forms of stem cell research. Given that brain organoids partially recapitulate the development of the human brain, it is plausible that brain organoids could one day attain consciousness and perhaps even higher cognitive abilities. Brain organoid research therefore raises difficult questions about these organoids' moral status – questions that currently fall outside the scope of existing regulations and guidelines. This paper shows how these gaps (...) can be addressed. We outline a moral framework for brain organoid research that can address the relevant ethical concerns without unduly impeding this important area of research. (shrink)

Joshua Greene has argued that the empirical findings of cognitive science have implications for ethics. In particular, he has argued (1) that people’s deontological judgments in response to trolley problems are strongly influenced by at least one morally irrelevant factor, personal force, and are therefore at least somewhat unreliable, and (2) that we ought to trust our consequentialist judgments more than our deontological judgments when making decisions about unfamiliar moral problems. While many cognitive scientists have rejected Greene’s dual-process theory (...) of moral judgment on empirical grounds, philosophers have mostly taken issue with his normative assertions. For the most part, these two discussions have occurred separately. The current analysis aims to remedy this situation by philosophically analyzing the implications of moral dilemma research using the CNI model of moral decision-making – a formalized, mathematical model that decomposes three distinct aspects of moral-dilemma judgments. In particular, we show how research guided by the CNI model reveals significant conceptual, empirical, and theoretical problems with Greene’s dual-process theory, thereby questioning the foundations of his normative conclusions. (shrink)

Does a diagnosis of brain dysfunction matter for ascriptions of moral responsibility? This chapter argues that, while knowledge of brain pathology can inform judgments of moral responsibility, its evidential value is currently limited for a number of practical and theoretical reasons. These include the problem of establishing causation from correlational data, drawing inferences about individuals from group data, and the reliance of the interpretation of brain findings on well-established psychological findings. Brain disorders sometimes matter (...) for moral responsibility, however, because they change an individual’s moral psychology in a way that is beyond their control. While control over psychological changes is not an excusing factor, brain disorders can mitigate moral responsibility because they confront individuals with new psychological deficits or urges for which their previous moral education and existing external and internal moral resources have not prepared them. (shrink)

Although philosophers have explored several connections between neuroscience and moral responsibility, the issue of how real-world neurological modifications, such as Deep Brain Stimulation, impact moral responsibility has received little attention. In this article, we draw on debates about the relevance of history and manipulation to moral responsibility to argue that certain kinds of neurological modification can diminish the responsibility of the agents so modified. We argue for a historicist position - a version of the history-sensitive reflection (...) view - and defend that account against a rival, relational view of responsibility. We conclude that DBS can, under certain conditions, diminish responsibility, and explore the circumstances under which this might be so. We conclude by suggesting that philosophical debates about moral responsibility, manipulation, and history have greater practical relevance than is sometimes thought, and that attention to practical cases can help inform and deepen this body of scholarship. (shrink)

Deep Brain Stimulation is currently being investigated as an experimental treatment for patients suffering from treatment-refractory AN, with an increasing number of case reports and small-scale trials published. Although still at an exploratory and experimental stage, initial results have been promising. Despite the risks associated with an invasive neurosurgical procedure and the long-term implantation of a foreign body, DBS has a number of advantageous features for patients with SE-AN. Stimulation can be fine-tuned to the specific needs of the particular (...) patient, is relatively reversible, and the technique also allows for the crucial issue of investigating and comparing the effects of different neural targets. However, at a time when DBS is emerging as a promising investigational treatment modality for AN, lesioning procedures in psychiatry are having a renaissance. Of concern it has been argued that the two kinds of interventions should instead be understood as rivaling, yet “mutually enriching paradigms” despite the fact that lesioning the brain is irreversible and there is no evidence base for an effective target in AN. We argue that lesioning procedures in AN are unethical at this stage of knowledge and seriously problematic for this patient group, for whom self-control is particularly central to wellbeing. They pose a greater risk of major harms that cannot justify ethical equipoise, despite the apparent superiority in reduced short term surgical harms and lower cost. (shrink)

Review of Harris Wiseman, The Myth of the Moral Brain: The Limits of Moral Enhancement, 340 pp.

Neuroimaging studies of brain-damaged patients diagnosed as in the vegetative state suggest that the patients might be conscious. This might seem to raise no new ethical questions given that in related disputes both sides agree that evidence for consciousness gives strong reason to preserve life. We question this assumption. We clarify the widely held but obscure principle that consciousness is morally significant. It is hard to apply this principle to difficult cases given that philosophers of mind distinguish between a (...) range of notions of consciousness and that is unclear which of these is assumed by the principle. We suggest that the morally relevant notion is that of phenomenal consciousness and then use our analysis to interpret cases of brain damage. We argue that enjoyment of consciousness might actually give stronger moral reasons not to preserve a patient's life and, indeed, that these might be stronger when patients retain significant cognitive function. (shrink)

Neuroimaging studies of brain-damaged patients diagnosed as in the vegetative state suggest that the patients might be conscious. This might seem to raise no new ethical questions given that in related disputes both sides agree that evidence for consciousness gives strong reason to preserve life. We question this assumption. We clarify the widely held but obscure principle that consciousness is morally significant. It is hard to apply this principle to difficult cases given that philosophers of mind distinguish between a (...) range of notions of consciousness and that is unclear which of these is assumed by the principle. We suggest that the morally relevant notion is that of phenomenal consciousness and then use our analysis to interpret cases of brain damage. We argue that enjoyment of consciousness might actually give stronger moral reasons not to preserve a patient's life and, indeed, that these might be stronger when patients retain significant cognitive function. (shrink)

Human brain organoids (HBOs) are three-dimensional biological entities grown in the laboratory in order to recapitulate the structure and functions of the adult human brain. They can be taken to be novel living entities for their specific features and uses. As a contribution to the ongoing discussion on the use of HBOs, the authors identify three sets of reasons for moral concern. The first set of reasons regards the potential emergence of sentience/consciousness in HBOs that would endow (...) them with a moral status whose perimeter should be established. The second set of moral concerns has to do with an analogy with artificial womb technology. The technical realization of processes that are typically connected to the physiology of the human body can create a manipulatory and instrumental attitude that can undermine the protection of what is human. The third set concerns the new frontiers of biocomputing and the creation of chimeras. As far as the new frontier of organoid intelligence is concerned, it is the close relationship of humans with new interfaces having biological components capable of mimicking memory and cognition that raises ethical issues. As far as chimeras are concerned, it is the humanization of nonhuman animals that is worthy of close moral scrutiny. A detailed description of these ethical issues is provided to contribute to the construction of a regulative framework that can guide decisions when considering research in the field of HBOs. (shrink)

For much of the twentieth century, philosophy and science went their separate ways. In moral philosophy, fear of the so-called naturalistic fallacy kept moral philosophers from incorporating developments in biology and psychology. Since the 1990s, however, many philosophers have drawn on recent advances in cognitive psychology, brain science, and evolutionary psychology to inform their work. This collaborative trend is especially strong in moral philosophy, and these three volumes bring together some of the most innovative work by (...) both philosophers and psychologists in this emerging interdisciplinary field. The neuroscience of morality is in its infancy, with the first brain imaging studies of moral development undertaken only in 2001. The contributors to volume 3 sample the best work in this very new field, discussing a variety of approaches, including functional imaging, lesion studies, abnormal psychology, and developmental neuroscience. Each chapter includes an essay, comments on the essay by other scholars, and a reply by the author of the original essay. Topics include the neural basis of moral emotions and moral judgments as well as comparisons of normal adult moral judgments with those made by children, adolescents, and people with psychopathy, brain damage, and autism. Contributors to Volume 3 Abigail Baird, William Casebeer, Cordelia Fine, Nathan Fox, Uta Frith, Jordan Grafman, Joshua Greene, Catherine Hynes, Fatima Azavedo Ignacio, Richard Joyce, Jerome Kagan, Leonard Katz, Kent Kiehl, Jeanette Kennett, Melanie Killen, Daniel Lapsley, Heidi Maibom, Victoria McGeer, John Mikhail, Jorge Moll, Shaun Nichols, Ricardo de Oliveira-Souza, Adina Roskies, Jana Schaich Borg, Katrina Sifferd, Walter Sinnott-Armstrong, Michael Smith, Mark Timmons, Frederick de Vignemont, Paul Whalen, Roland Zahn. (shrink)

We argue that in implanted neurotechnology research, participants and researchers experience what Henry Richardson has called “moral entanglement.” Participants partially entrust researchers with access to their brains and thus to information that would otherwise be private, leading to created intimacies and special obligations of beneficence for researchers and research funding agencies. One of these obligations, we argue, is about continued access to beneficial technology once a trial ends. We make the case for moral entanglement in this context through (...) exploration of participants’ vulnerability, uncompensated risks and burdens, depth of relationship with the research team, and dependence on researchers in implanted neurotechnology trials. (shrink)

The author comments on the article “The neurobiology of addition: Implications for voluntary control of behavior,‘ by S. E. Hyman. The author agrees with Hyman that debate persists whether addiction is a brain disease or a moral condition. The author suggests that even if we understand the neurobiology of addiction, it will make sense to seek accountability from the addict and to modify his behavior. He also suggests that no facts about neurobiology will change these moral requirements. (...) Accession Number: 24077917; Authors: Cochrane, Thomas I. 1; Email Address: [email protected]; Affiliations: 1: Harvard Medical School; Subject: EDITORIALS; Subject: ADDICTIONS; Subject: NEUROBIOLOGY; Subject: BEHAVIOR; Subject: HYMAN, S. E.; Number of Pages: 2p. (shrink)

Clinical Ethics, Ahead of Print. The migration of health-care professionals has often produced morally charged discussions among ethicists, politicians, and policy makers in the migrant-sending and migrant-receiving countries because of its devastating effects on the health of those left behind in the countries of origin.This movement of skilled professionals – their decision to leaving their countries of origin in search of better work environments – has created a phenomenon that has been described as brain drain. Although the migration of (...) health workers continue to bring prosperity to millions of people around the world, they have also evoked hopelessness in many more people. Thus, questions of global justice manifest themselves when it comes to the matters of brain drain and the just distribution of health and healthcare professionals. (shrink)

For much of the twentieth century, philosophy and science went their separate ways. In moral philosophy, fear of the so-called naturalistic fallacy kept moral philosophers from incorporating developments in biology and psychology. Since the 1990s, however, many philosophers have drawn on recent advances in cognitive psychology, brain science, and evolutionary psychology to inform their work. This collaborative trend is especially strong in moral philosophy, and these three volumes bring together some of the most innovative work by (...) both philosophers and psychologists in this emerging interdisciplinary field. The neuroscience of morality is in its infancy, with the first brain imaging studies of moral development undertaken only in 2001. The contributors to volume 3 sample the best work in this very new field, discussing a variety of approaches, including functional imaging, lesion studies, abnormal psychology, and developmental neuroscience. Each chapter includes an essay, comments on the essay by other scholars, and a reply by the author of the original essay. Topics include the neural basis of moral emotions and moral judgments as well as comparisons of normal adult moral judgments with those made by children, adolescents, and people with psychopathy, brain damage, and autism. Contributors to volume 3:_ _Abigail Baird, William Casebeer, Cordelia Fine, Nathan Fox, Uta Frith, Jordan Grafman, Joshua Greene, Catherine Hynes, Fatima Azavedo Ignacio, Richard Joyce, Jerome Kagan, Leonard Katz, Kent Kiehl, Jeanette Kennett, Melanie Killen, Daniel Lapsley, Heidi Maibom, Victoria McGeer, John Mikhail, Jorge Moll, Shaun Nichols, Ricardo de Oliveira-Souza, Adina Roskies, Jana Schaich Borg, Katrina Sifferd, Walter Sinnott-Armstrong, Michael Smith, Mark Timmons, Frederick de Vignemont, Paul Whalen, Roland Zahn. (shrink)

Human aesthetic experiences are pervasive; they are triggered by faces, art, natural scenery, foods, ideas, theories, and decision-making situations, among many sources, and seem to be a distinctive trait of our species. Our moral sense, understood as our capacity to judge events, actions, or people as good or bad, appropriate or inappropriate, also seems to be an exclusively human endowment (Ayala 2010). As part of the scientific efforts to characterize the biological foundations of our human uniqueness, recently there has (...) been interest in the brain’s underpinnings of aesthetic reactions to art on the one hand, and in the neural correlates of moral judgment and decision-making on the other (Greene and Paxton .. (shrink)

How should ethics help decide the morality of enhancing morality? The idea of morally enhancing the human brain quickly emerged when the promise of cognitive enhancement in general began to seem realizable. However, on reflection, achieving moral enhancement must be limited by the practical challenges to any sort of cognitive modification, along with obstacles particular to morality’s bases in social cognition. The objectivity offered by the brain sciences cannot ensure the technological achievement of moral bioenhancement for (...) humanity-wide application. Additionally, any limited moral enhancement will not easily fulfil ethical expectations. Three hypothetical scenarios involving putative moral enhancement help illustrate why. Philosophical concerns about the “Does-Must Dichotomy” and the “Factor-Cause Plurality,” as I label them, forbid easy leaps from views about morality on to conclusions about ways to enhance morality, and then further on to ethically justifying those enhancements. A modest and realistic approach to moral enhancement emerges from exploring these issues. (shrink)

Recent advances in human brain organoid systems have raised serious worries about the possibility that these in vitro ‘mini‐brains’ could develop sentience, and thus, moral status. This article considers the relative moral status of sentient human brain organoids and research animals, examining whether we have moral reasons to prefer using one over the other. It argues that, contrary to common intuitions, the wellbeing of sentient human brain organoids should not be granted greater moral (...) consideration than the wellbeing of nonhuman research animals. It does so not by denying that typical humans have higher moral status than animals, but instead by arguing that none of the leading justifications for granting humans higher moral status than nonhuman animals apply to brain organoids. Additionally, it argues that there are no good reasons to be more concerned about the well‐being of human brain organoids compared to those generated from other species. (shrink)

Singer claims that there are two ways of challenging the fact that brain-dead patients, from whom organs are usually retrieved, are in fact biologically alive. By means of the first, the so called dead donor rule may be abandoned, opening the way to lethal organ donation. In the second, it might be posited that terms such as “life” and “death” do not have any primary biological meaning and are applicable to persons instead of organisms. This second possibility permits one (...) to acknowledge that brain-dead patients are deceased because they are irreversibly unconscious. In the commentary which follows, I will argue that Singer’s second option is preferable since it provides a higher amount of organs available for transplant, and is better suited to the meaning of “death” which occurs in ordinary language. I will also defend such a concept of death against the objections raised by Michael Nair-Collins in the article Can the brain-dead be harmed or wronged? On the moral status of brain death and its implications for organ transplantation. (shrink)

Introduction -- The mischievous neuron -- The shadow of determinism -- The essential freedom -- A tempest in the brain -- Neurological disturbance -- The seat of the will -- The somatic-marker hypothesis -- The readiness potential -- The grand illusion -- Neuronal destiny -- The revolution of the brain -- Seeds of corruption -- Morality's end -- The depths of consciousness -- A challenge for experience -- The boundlessness of reason -- Rise of the moral agent (...) -- The palace of the mind. (shrink)

In this paper I first argue that when answering the question of whether or not governments may restrict emigration, Brock and Blake are staking out positions not astronomically far from one another. Despite the ostensibly large philosophical gap between the two, both think that certain governments may restrict emigration when such restriction is agreed to in a morally binding contract. Secondly, both authors think that there are specific “circumstances” or “conditions” under which a contract that restricts emigration can be morally (...) binding. This second part of the paper will pose some questions that explore these various circumstances or conditions. The ultimate aim of the paper is to help point the debate in the right direction so as to further develop an answer to the question of whether or not governments may restrict emigration. (shrink)

Human brain organoids (HBOs) are novel entities that may exhibit unique forms of cognitive potential. What moral status, if any, do they have? Several authors propose that consciousness may hold the answer to this question. Others identify various _kinds of_ consciousness as crucially important for moral consideration, while leaving open the challenge of determining whether HBOs have them. This paper aims to make progress on these questions in two ways. First, it proposes a framework for thinking about (...) the moral status of entities other than paradigmatic persons. This framework identifies four qualities that ground moral status: evaluative stance, self-directedness, agency, and other-directedness. Second, we speculate on ways in which these qualities are relevant to dimensions of conscious experience that have been, or could be, identified in nonhuman animals. We further explore how these approaches could be adapted for use in HBOs, and argue that such studies, or something similar to them, will have to be performed if we wish to have empirical indications that HBOs have consciousness of a morally significant kind. We end by proposing that in our current scientific and epistemic situation, it is too soon to attribute any moral status to HBOs, but that this might change in the future. (shrink)