Poser la question de la provenance du geste critique instaurant le pré-monde (Vorwelt) revient à s’interroger de manière plus générale sur le commencement ou plus précisément sur le fondement de L’Étoile de la Rédemption. À cette question, qui pourrait être qualifiée elle-même de fondamentale, Franz Rosenzweig fait remarquer tout d’abord, dans « La pensée nouvelle », qu’« à l’égard des premières pages d’un livre de philosophie, les lecteurs ont une attitude singulière : ils croient qu’elles c...

tome 1. Mémoires ; Traité de la cause et des phénomènes de l'électricité ; Lettre à M. Nollet sur l'électricité ; avec l'Histoire d'Alexandre le Grand.

English summary: Jean-Francois Revel (1924-2006) was an essential intellectual and author of the twentieth century. His work explored the ideological sources that fed the various forms of totalitarianism, from Communism to Islamism. The present biography sheds light on the multiple aspects of this combative thought couched in the will affirm the principals of both economic and political liberal democracy. French description: Loin de n'avoir ete qu'un polemiste de talent, Jean-Francois Revel (1924-2006) a ete, de Pourquoi des philosophes? (1957) a L'Obsession (...) antiamericaine (2002), l'auteur d'une oeuvre de premiere importance, jalonnee par de fracassants succes populaires et internationaux. Allant bien au-dela du seul engagement anticommuniste, la force et la singularite intellectuelles de sa pensee n'avaient jamais, jusqu'ici, fait l'objet d'une synthese exhaustive qui aurait permis d'en eclairer la place dans l'histoire contemporaine des idees - une beance que le present ouvrage vient enfin combler. Avant tout anime par la passion des faits, ce philosophe s'est constamment employe a pourfendre et a deconstruire les impostures ideologiques dont se sont nourries les diverses tentations totalitaires qui ont marque le XXe siecle, jusque sous leurs recents avatars de l'islamisme et de l'antiracisme devoye. Philippe Boulanger, dans cette passionnante biographie intellectuelle, expose les etapes successives et les multiples aspects de cette pensee de combat qui trouve son unite profonde dans la volonte de reaffirmer sans concession l'insigne valeur des principes d'une democratie liberale, en economie comme en politique. Chaque jour qui passe semble en rappeler l'intempestive et remarquable pertinence. (shrink)

La question de l’ennemi et de la guerre chez Rosenzweig est importante non seulement pour comprendre l’auteur, mais aussi son œuvre : L’Étoile de la Rédemption. Avec la relation d’hostilité, la temporalité rédemptrice basée sur le commandement d’amour s’affronte au problème des rapports qu’ont le judaïsme et le christianisme avec la guerre et le nationalisme.

« Pricer », « marketer », « auto-fixing », curation, diffusion, réflexivité : cet article explore quelques-uns des innombrables ruses par lesquelles la raison de l’art jongle avec les valeurs du marché. Des travaux de Claude Rutault et Ben Kinmont servent de contre-exemples à certaines tendances dominantes.

« Pricer », « marketer », « auto-fixing », curation, diffusion, réflexivité : cet article explore quelques-uns des innombrables ruses par lesquelles la raison de l’art jongle avec les valeurs du marché. Des travaux de Claude Rutault et Ben Kinmont servent de contre-exemples à certaines tendances dominantes.

Dans le prolongement de sa thèse sur les enfants abandonnés en Bretagne, soutenue en 2010 à l’université de Rennes, Isabelle Le Boulanger esquisse dans ce volume, en relisant ses notes d’archives, une étude des agressions sexuelles commises sur des enfants dans la Bretagne du xixe siècle. Son corpus est constitué d’un échantillon aléatoire d’archives judiciaires (dépouillement d’une année de dossiers de procédure par décennie), au demeurant inégalement conservées dans les cinq départements qu...

Nicolas-Antoine Boulanger, ingénieur, homme de lettres et philosophe français, fut admiré ou redouté par plusieurs de ses contemporains les plus illustres. Il a également fourni des articles de droit à l'Encyclopédie de Diderot et D'Alembert. Le présent ouvrage constitue la première étude d'ensemble de cet écrivain.

This paper argues that international development research should be submitted to the oversight of research ethics committees from the countries where data will be collected. This includes research conducted by individuals who may fall outside the jurisdictions of most ethics guidelines or policies, such as individuals contracted by non-governmental organizations. The argument is grounded in an understanding of social justice that recognizes that not seeking local ethics approval can be an affront to the decolonization movement, and may lead to significant (...) direct harms to participants. Local ethics oversight can help ensure projects appropriately take into consideration local laws, regulations, priorities and context. For example, a local research ethics committee may be in a better position than a foreign one to assess whether any given proposed project carries context-specific risks. In addition, submitting to a local research ethics committee is to acknowledge the legitimacy of local authorities, thereby taking a stance against the history of colonizing disempowerment. Local oversight is a mechanism to increase the accountability of researchers working abroad: if respect for local authority and tailoring to local context are to be upheld, there must be mechanisms to ensure that research that does not meet these requirements does not proceed. Objections based on the limited oversight capacity in some countries and on concerns related to the politicization of the review process are discussed. Finally, the roles and responsibilities of the various stakeholders in the implementation of greater local ethics oversight are laid out. (shrink)

Prominent tuberculosis (TB) actors are invoking solidarity to motivate and justify collective action to address TB, including through intensified development and implementation (D&I) of technologies such as drugs and diagnostics. We characterize the ethical challenges associated with D&I of new TB technologies by drawing on stakeholder perspectives from 23 key informant interviews and we articulate the ethical implications of solidarity for TB technology D&I. The fundamental ethical issue facing TB technological D&I is a failure within and beyond the TB community (...) to stand in solidarity with persons with TB in addressing the complex sociopolitical contexts of technological D&I. The failure in solidarity relates to two further ethical challenges raised by respondents: skewed power dynamics that hinder D&I and uncertainties around weighing risks and benefits associated with new technologies. Respondents identified advocacy and participatory research practices as necessary to address such challenges and to motivate sustained collective action to accelerate toward TB elimination. We present the first empirical examination of bioethical accounts of solidarity in public and global health. Our study suggests that solidarity allows us better to understand and address the ethical challenges that arrest the D&I of new TB technologies. Solidarity lends credence to policies and practices that address the relational nature of illness and health through collective action. (shrink)

ObjectiveTo identify the ethical challenges associated with the development and implementation of new tuberculosis drugs and diagnostics.MethodsTwenty-three semi-structured qualitative interviews conducted between December 2015 and September 2016 with programme administrators, healthcare workers, advocates, policymakers, and funders based in the Americas, Europe, and Africa. Interviews were analysed using thematic analysis.ResultsDivergent interests and responsibilities, coupled with power imbalances, are a primary source of ethical challenges; the uncertain risk profiles of new drugs present an additional one. Although this challenge can be partially mitigated (...) through stringent pharmacovigilance, respondents highlighted that high-burden countries tend to lack the resources to facilitate safe implementation. Increased advocacy and community engagement are considered an ethical imperative for future TB development and implementation.ConclusionsThis project helps identify some of the ethical challenges of new TB technologies. It demonstrates that investigating ethical challenges through qualitative research is one way to apprehend the difficulty of implementing new TB technologies. Addressing this difficulty will require that those in positions of power reconsider their interests in relation to disempowered communities.Policy implicationsEfforts to build consensus regarding what values should underpin the global governance of TB research, prevention, and care are essential to facilitate the ethical implementation of new TB technologies. (shrink)

The culmination of three decades of studying and treating survivors of adult onset trauma, _Wounded by Reality_ is the first systematic attempt to differentiate adult onset trauma from childhood trauma, with which it is frequently confused. When catastrophic events overtake adult lives, they often scar the psyche in ways that psychodynamically oriented clinicians struggle to understand. For Ghislaine Boulanger, the enormous challenge of working with these patients is unsurprising. Survivors of major catastrophe, whether a natural disaster, a life-threatening assault, (...) a serious accident, or an act of terrorism, experience a near-fatal disruption of fundamental aspects of self experience. The sense of agency, of affectivity, of bodily integrity, the capacity for self-reflection, the sense of time, and the ability to relate to others - all are called into question. (shrink)

Disaster research has grown in scope and frequency. Research in the wake of disasters and during humanitarian crises – particularly in resource-poor settings – is likely to raise profound and unique ethical challenges for local communities, crisis responders, researchers, and research ethics committees. Given the ethical challenges, many have questioned how best to provide research ethics review and oversight. We contribute to the conversation concerning how best to ensure appropriate ethical oversight in disaster research and argue that ethical disaster research (...) requires of researchers and RECs a particular sort of ongoing, critical engagement which may not be warranted in less exceptional research. We present two cases that typify the concerns disaster researchers and RECs may confront, and elaborate upon what this ongoing engagement might look like – how it might be conceptualized and utilized – using the concept of real-time responsiveness. The central aim of RTR, understood here as both an ethical ideal and practice, is to lessen the potential for research conducted in the wake of disasters to create, perpetuate, or exacerbate vulnerabilities and contribute to injustices suffered by disaster-affected populations. Well cultivated and deployed, we believe that RTR may enhance the moral capacities of researchers and REC members, and RECs as institutions where moral agency is nurtured and sustained. (shrink)

D. Boulanger. Colloque Lamarck Paris, Vrin, 1980 EVOLUTION DU GROUPE DES NUMMULITES C'est en 1801 que Lamarck dans son Système des animaux sans vertèbres proposa le genre Nummulites qu'il considéra comme le 89e des ...

Developing Global Health Programming: A Guidebook for Medical and Professional Schools , edited by Jessica Evert, Paul Drain, and Thomas Hall, is reviewed. In spite of some editorial shortcomings, the book is a terrific aggregation of resources and reflections on the state of global health education that leaves readers with a multitude of useful and diverse tools, as well as directions about where to find additional ones.

This article examines how non-linear time and circularity are deployed in the historical novel Nehanda, written by Zimbabwean author Yvonne Vera. Using Adriana Cavarero’s work on inclination...

Neuronal remodeling is a conserved mechanism that eliminates unwanted neurites and can include the loss of cell bodies. In these processes, a key role for glial cells in events from synaptic pruning to neuron elimination has been clearly identified in the last decades. Signals sent from dying neurons or neurites to be removed are received by appropriate glial cells. After receiving these signals, glial cells infiltrate degenerating sites and then, engulf and clear neuronal debris through phagocytic mechanisms. There are few (...) identified or proposed signals and receptors involved in neuron‐glia crosstalk, which induces the transformation of glial cells to phagocytes during neuronal remodeling in Drosophila. Many of these signaling pathways are conserved in mammals. Here, we particularly emphasize the role of Orion, a recently identified neuronal CX3C chemokine‐like secreted protein, which induces astrocyte infiltration and engulfment during mushroom body neuronal remodeling. Although, chemokine signaling was not described previously in insects we propose that chemokine‐like involvement in neuron/glial cell interaction is an evolutionarily ancient mechanism. (shrink)

The American Journal of Bioethics, Volume 11, Issue 10, Page 24-26, October 2011.

This book closely examines our commonly held beliefs about human suffering, and offers unique insights into God's role in why we suffer. Dr. Perri critically examines what it means to be human from a Judeo-Christian perspective, and extrapolates from the work of Carl Gustav Jung showing a deeply complex development of human transcendence in human suffering. On an interpersonal level, Dr. Perri elaborates on the work of Martin Buber and Emanuel Levinas and shows how our suffering can be shared and (...) lessened by our unconditionality and presence for the other. Scriptural passages are quoted from both the Hebrew and New Testament texts, and are used to depict the suffering of humankind as seen in the face of Job. It was this face, according to Perri, that Jesus saw in the faces of those He came to redeem, and that ultimately brought Him to the crucifix of redemption. Dr. Perri challenges Sartre's position that our existence precedes our essence, and draws on the work of Abraham Joshua Heschel and Christian theology in this regard. He further elaborates a neurodevelopmental paradigm that creates essence as the basis of our freedom to choose. This book can be read and studied by both professionals in the helping and healing professions, and lay persons seeking to better understand our suffering, and how to better help those who suffer. Dr. Perri offers specific ways in how to be present for those who suffer, how to read and receive the hidden language of human suffering, and how to use silence as a communication skill. (shrink)

Voici une dition qui contribuera sans doute clairer une activit encore mal connue de Voltaire, celle d' diteur. Car de cette uvre composite qu'est le Discours de l'empereur Julien Voltaire se veut avant tout et reste bien l'organisateur, empruntant l'empereur du IVe si cle le r quisitoire qu'il a dress dans son Contre les Galil ens et au marquis d'Argens, son moderne et premier traducteur, la 'belle infid le' qu'il a donn e lire cinq ans plus t t ceux qui (...) n'entendaient ni le grec ni le latin. Voltaire n'a cependant conserv le joyau que pour le servir dans une monture toute nouvelle: d'Argens avait accompagn sa traduction d'une substantielle pr face et d'une annotation abondante; mais Voltaire a cart la premi re et retenu un tiers seulement de la seconde, encadrant d sormais le Discours de ses propres textes; en pr faces un 'Avis au lecteur' suivi d'un 'Portrait de l'empereur Julien' et d'un 'Examen du Discours'; en postface un virulent 'Suppl ment au Discours'. A quoi l'on ajoutera les quarante-quatre notes r dig es par l' diteur et qui s'adjoignent aux treize notes de d'Argens qu'il a conserv es; ce sont les 'nouvelles notes de divers auteurs' annonc s par la page de titre et dont quatre sont sign es Damilaville, Boulanger, Bolingbroke et 'le th ologien Th ro': sous ces noms d'emprunt, l' diteur ne s'est pas fait scrupule de r utiliser certains de ses textes ant rieurs, pas plus qu'il n'a craint, par de simples coupes habilement op r es dans certaines notes de d'Argens, de d figurer l'occasion la pens e du marquis quand elle se trouve contraire la sienne. Ainsi voit-on clairer sous ses diff rents aspects une activit ditoriale dont il fallait aussi p n trer les motifs. (shrink)

The draft Code of Conduct for Research is an important initiative towards assisting the scientific community in complying with the provisions of the Protection of Personal Information Act 4 of 2013 (POPIA). However, its approach towards cross-border data sharing should be reconsidered to clarify the ambiguities inherent in the legal requirements for the cross-border sharing of health data in the POPIA. These ambiguities include the concept of ‘transfer of information’, the application of adequacy as a legal mechanism for transfer, the (...) nature of consent for cross-border sharing and the scope of the recipient third party. We suggest that the draft Code of Conduct for Research can be improved by: Explaining or defining the concept of ‘transfer of information’ and when it applies to cross-border sharing in research Clarifying the application of adequacy as a legal mechanism for transfer vis-à-vis the other alternatives Expanding on the interpretation and application of consent as a legal mechanism for cross-border transfers Expanding the category of persons who may be recipients of personal information in a third country. (shrink)