Journal of Bioethical Inquiry 17 (1):65-73 (2020)
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ObjectiveTo identify the ethical challenges associated with the development and implementation of new tuberculosis drugs and diagnostics.MethodsTwenty-three semi-structured qualitative interviews conducted between December 2015 and September 2016 with programme administrators, healthcare workers, advocates, policymakers, and funders based in the Americas, Europe, and Africa. Interviews were analysed using thematic analysis.ResultsDivergent interests and responsibilities, coupled with power imbalances, are a primary source of ethical challenges; the uncertain risk profiles of new drugs present an additional one. Although this challenge can be partially mitigated through stringent pharmacovigilance, respondents highlighted that high-burden countries tend to lack the resources to facilitate safe implementation. Increased advocacy and community engagement are considered an ethical imperative for future TB development and implementation.ConclusionsThis project helps identify some of the ethical challenges of new TB technologies. It demonstrates that investigating ethical challenges through qualitative research is one way to apprehend the difficulty of implementing new TB technologies. Addressing this difficulty will require that those in positions of power reconsider their interests in relation to disempowered communities.Policy implicationsEfforts to build consensus regarding what values should underpin the global governance of TB research, prevention, and care are essential to facilitate the ethical implementation of new TB technologies.
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DOI | 10.1007/s11673-019-09954-w |
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References found in this work BETA
Reciprocity and Ethical Tuberculosis Treatment and Control.Diego S. Silva, Angus Dawson & Ross E. G. Upshur - 2016 - Journal of Bioethical Inquiry 13 (1):75-86.
Ethics and Infectious Disease.Michael Selgelid, Margaret Battin & Charles B. Smith (eds.) - 2006 - Wiley.
Reciprocity-Building and the Importance of Interdisciplinary Collaboration in Tuberculosis Research.P. H. Mason, A. Roy & P. Singh - 2017 - Journal of Biosocial Science 49 (4):559-562.
Ethics, Tuberculosis and Globalization.Michael J. Selgelid - 2008 - Public Health Ethics 1 (1):10-20.
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Citations of this work BETA
Lead Essay: Money, Equity and Access to Medicines.Narcyz Ghinea, Wendy Lipworth & Ian Kerridge - 2020 - Journal of Bioethical Inquiry 17 (1):25-27.
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