21 found
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  1.  23
    Toward a Framework for Assessing Privacy Risks in Multi-Omic Research and Databases.Charles Dupras & Eline M. Bunnik - 2021 - American Journal of Bioethics 21 (12):46-64.
    While the accumulation and increased circulation of genomic data have captured much attention over the past decade, privacy risks raised by the diversification and integration of omics have been la...
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  2.  84
    Epigenetics and the Environment in Bioethics.Charles Dupras, Vardit Ravitsky & Bryn Williams-Jones - 2012 - Bioethics 28 (7):327-334.
    A rich literature in public health has demonstrated that health is strongly influenced by a host of environmental factors that can vary according to social, economic, geographic, cultural or physical contexts. Bioethicists should, we argue, recognize this and – where appropriate – work to integrate environmental concerns into their field of study and their ethical deliberations. In this article, we present an argument grounded in scientific research at the molecular level that will be familiar to – and so hopefully more (...)
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  3.  49
    Epigenetics in the Neoliberal “Regime of Truth”.Charles Dupras & Vardit Ravitsky - 2015 - Hastings Center Report 46 (1):26-35.
    Recent findings in epigenetics have been attracting much attention from social scientists and bioethicists because they reveal the molecular mechanisms by which exposure to socioenvironmental factors, such as pollutants and social adversity, can influence the expression of genes throughout life. Most surprisingly, some epigenetic modifications may also be heritable via germ cells across generations. Epigenetics may be the missing molecular evidence of the importance of using preventive strategies at the policy level to reduce the incidence and prevalence of common diseases. (...)
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  4.  36
    Noninvasive Prenatal Testing: Views of Canadian Pregnant Women and Their Partners Regarding Pressure and Societal Concerns.Vardit Ravitsky, Stanislav Birko, Jessica Le Clerc-Blain, Hazar Haidar, Aliya O. Affdal, Marie-Ève Lemoine, Charles Dupras & Anne-Marie Laberge - 2021 - AJOB Empirical Bioethics 12 (1):53-62.
    Background Noninvasive prenatal testing (NIPT) provides important benefits yet raises ethical concerns. We surveyed Canadian pregnant women and their partners to explore their views regarding pressure to test and terminate a pregnancy, as well as other societal impacts that may result from the routinization of NIPT.Methods A questionnaire was offered (March 2015 to July 2016) to pregnant women and their partners at five healthcare facilities in four Canadian provinces.Results 882 pregnant women and 395 partners completed the survey. 64% of women (...)
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  5.  23
    The ambiguous nature of epigenetic responsibility.Charles Dupras & Vardit Ravitsky - 2016 - Journal of Medical Ethics 42 (8):534-541.
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  6.  32
    Race in the Postgenomic Era: Social Epigenetics Calling for Interdisciplinary Ethical Safeguards.Katie M. Saulnier & Charles Dupras - 2017 - American Journal of Bioethics 17 (9):58-60.
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  7.  18
    Fair Subject Selection Procedures Must Consider Scientific Uncertainty and Variability in Risk and Benefit Perception.Charles Dupras & Elise Smith - 2020 - American Journal of Bioethics 20 (2):33-35.
    Volume 20, Issue 2, February 2020, Page 33-35.
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  8. Biopolitical Barriers to a Potterian Bioethics: The (Potentially) Missed Opportunity of Epigenetics.Charles Dupras, Bryn Williams-Jones & Vardit Ravitsky - 2017 - American Journal of Bioethics 17 (9):15-17.
    Lee (2017) calls for greater attention to the shared epistemological and normative grounds of both public health ethics and environmental ethics, and to Potter’s original conception of bioethics, which, as she rightly observes, has been largely disregarded in contemporary North American bioethics scholarship and practice. In a previous publication we also argued in favor of reviving the Potterian approach to bioethics; we built a case grounded in “the relatively new field of molecular epigenetics [that] provides novel information that should serve (...)
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  9.  54
    Rapprochement Des pôles nature et culture Par la recherche en épigénétique : Dissection d’un bouleversement épistémologique attendu.Charles Dupras - 2017 - Les Ateliers de l'Éthique / the Ethics Forum 12 (2-3):120-145.
    CHARLES DUPRAS | : L’épigénétique est un champ d’études qui s’intéresse aux modifications biochimiques et aux changements dans la structure tridimensionnelle de l’ADN ayant pour effet de contraindre ou de faciliter la lecture et l’expression des gènes. Au cours des dix dernières années, l’épigénétique a attiré l’attention d’un nombre croissant de chercheurs en sciences sociales, puisqu’elle semble venir confirmer, cette fois sur le plan moléculaire, le rôle déterminant de l’environnement développemental des personnes dans la configuration de leur individualité biologique et (...)
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  10.  14
    Beyond Advocacy: Human Health, the Environment, and Tradeoff Ethics.Valentina de Maack, Sandy Tubeuf, Charlotte Desterbecq & Charles Dupras - 2024 - American Journal of Bioethics 24 (3):50-52.
    In “The Bioethics of Environmental Injustice,” Ray and Cooper (2024) lay out compelling arguments to increase attention to environmental health within bioethics. Advocacy is crucial, they argue, co...
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  11.  29
    Defusing the legal and ethical minefield of epigenetic applications in the military, defence and security context.Gratien Dalpe, Katherine Huerne, Charles Dupras, Katherine Cheung, Nicole Palmour, Eva Winkler, Karla Alex, Maxwell Mehlmann, John W. Holloway, Eline Bunnik, Harald König, Isabelle M. Mansuy, Marianne G. Rots, Cheryl Erwin, Alexandre Erler, Emanuele Libertini & Yann Joly - 2023 - Journal of Law and the Biosciences 10 (2):1-32.
    Epigenetic research has brought several important technological achievements, including identifying epigenetic clocks and signatures, and developing epigenetic editing. The potential military applications of such technologies we discuss are stratifying soldiers’ health, exposure to trauma using epigenetic testing, information about biological clocks, confirming child soldiers’ minor status using epigenetic clocks, and inducing epigenetic modifications in soldiers. These uses could become a reality. This article presents a comprehensive literature review, and analysis by interdisciplinary experts of the scientific, legal, ethical, and societal issues (...)
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  12.  11
    Contending with Real and Perceived Intrusiveness in Digital Phenotyping Research.Josianne Barrette-Moran & Charles Dupras - 2024 - American Journal of Bioethics 24 (2):108-110.
    Shen et al.'s (2024) novel 3 × 3 ethical framework aims to facilitate “study-by-study decisions about returning individual research results (IRRs) from digital phenotyping in psychiatry.” The frame...
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  13. Impacts of the Early COVID-19 Pandemic on the Work of Bioethicists in Canada.Marilou Charron, Jean-Christophe Bélisle-Pipon, Vincent Couture, Bryn Williams-Jones, Vardit Ravitsky & Charles Dupras - 2022 - Canadian Journal of Bioethics / Revue canadienne de bioéthique 5 (4):20-29.
    Bioethics experts played a key role in ensuring a coherent ethical response to the COVID-19 pandemic in the fields of healthcare, public health, and scientific research in Canada. In the province of Quebec, a group of academic and practicing bioethicists met periodically in the early months of the pandemic to discuss approaches and solutions to ethical dilemmas encountered during the crisis. These meetings created the opportunity for a national survey of bioethics practitioners from different fields. The survey, in which forty-five (...)
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  14. BioéthiqueOnline: Moving to Peer-Review / BioéthiqueOnline : Passage à l’évaluation par les pairs.Zubin Master, Carolina Martin, Jason Behrmann, Charles Marsan, Lise Levesque, Maude Laliberté, Charles Dupras, Elise Smith, Renaud Boulanger, Jean-Christophe Belisle Pipon, Bryn Williams-Jones, Christopher McDougall, Ali Okhowat & Sonia Paradis - 2012 - BioéthiqueOnline 1 (Ed2).
  15. Imagining Truly Open Access Bioethics: From Dreams to Reality.Bryn Williams-Jones, Vincent Couture, Renaud Boulanger & Charles Dupras - 2017 - American Journal of Bioethics 17 (10):19-20.
    Imagine that you are part of the editorial board of a young bioethics journal committed to publishing open access (OA) and to ensuring accessibility to high quality and innovative scholarship. To support junior and interna- tional scholars who might not otherwise find places for their work in the leading Western bioethics journals, you do not charge author fees. Imagine also that you have no financial resources to pay for a professional website, auto- mated submissions manager, or even a part-time coordina- (...)
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  16.  19
    The omics of our lives: practices and policies of direct-to-consumer epigenetic and microbiomic testing companies.Terese Knoppers, Elisabeth Beauchamp, Ken Dewar, Sarah Kimmins, Guillaume Bourque, Yann Joly & Charles Dupras - 2021 - New Genetics and Society 40 (4):541-569.
    While much attention has gone towards ethical, legal, and social implications of direct-to-consumer genetic testing over the past decades, the rise of new forms of consumer omics has largely escaped scrutiny. In this paper, we analyze the product descriptions, promotional messages, terms of service, and privacy policies of five epigenetic and seven microbiomic testing companies. The advent of such tests online represents a significant shift in consumer omics, from a focus on inherited molecules with genetic tests, to broader interest for (...)
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  17. Launch of the Canadian Journal of Bioethics/Lancement de la Revue canadienne de bioéthique.Bryn Williams-Jones, Charles Dupras, Vincent Couture & Renaud Boulanger - 2018 - Canadian Journal of Bioethics/Revue canadienne de bioéthique 1 (1):1-3.
  18.  26
    Studying Vulnerable Populations Through an Epigenetics Lens: Proceed with Caution.Katie Saulnier, Alison Berner, Stamatina Liosi, Brian Earp, Courtney Berrios, Stephanie O. M. Dyke, Charles Dupras & Yann Joly - 2022 - Canadian Journal of Bioethics / Revue canadienne de bioéthique 5 (1).
    Epigenetics – the study of mechanisms that influence and modify gene expression – is providing unique insights into how an individual’s social and physical environment impact the body at a molecular level, particularly in populations that experience stigmatization and trauma. Researchers are employing epigenetic studies to illuminate how epigenetic modifications lead to imbalances in health outcomes for vulnerable populations. However, the investigation of factors that render a population epigenetically vulnerable present particular ethical and methodological challenges. Here we are concerned with (...)
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  19.  10
    Response to Open Peer Commentaries on Toward a Framework for Assessing Privacy Risks in Multi-Omic Research and Databases.Charles Dupras & Eline M. Bunnik - 2022 - American Journal of Bioethics 22 (9):4-6.
    In ‘Toward a Framework for Assessing Privacy Risks in Multi-Omic Research and Databases’ (Dupras and Bunnik 2021), we argued against the assessment of privacy risks and protection requirements base...
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  20.  14
    L'humour macabre : un mécanisme de défense acceptable en soins critiques?Alexandra Fortin & Charles Dupras - 2018 - Canadian Journal of Bioethics / Revue canadienne de bioéthique 1 (2):69-75.
    Health care professionals assigned to critical care are confronted on a daily basis with particularly trying situations. Their hard work conditions can become anxiety-provoking, affect their physical and/or psychological condition, decrease their performance and increase their absenteeism rate at work. To face this particularly stressful and sometimes depressing context, some professionals fall back on “gallows humour”, a sort of black humour with a morbid overtone, which is likely to shock certain people. Although gallows humour is very widespread, its use in (...)
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  21.  14
    L'humour macabre: un mécanisme de défense acceptable en soins critiques?Alexandra Fortin & Charles Dupras - 2018 - Canadian Journal of Bioethics/Revue canadienne de bioéthique 1 (2):69-75.
    Health care professionals assigned to critical care are confronted on a daily basis with particularly trying situations. Their hard work conditions can become anxiety-provoking, affect their physical and/or psychological condition, decrease their performance and increase their absenteeism rate at work. To face this particularly stressful and sometimes depressing context, some professionals fall back on “gallows humour”, a sort of black humour with a morbid overtone, which is likely to shock certain people. Although gallows humour is very widespread, its use in (...)
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