Large‐scale characterization of the human microbiota has largely focused on Western adults, yet these populations may be uncharacteristic because of their diets and lifestyles. In particular, the rise of “Western diseases” may in part stem from reduced exposure to, or even loss of, microbes with which humans have coevolved. Here, we review beneficial microbes associated with pathogen resistance, highlighting the emerging role of complex microbial communities in protecting against disease. We discuss ways in which modern lifestyles and practices may deplete (...) physiologically important microbiota, and explore prospects for reintroducing or encouraging the growth of beneficial microbes to promote the restoration of healthy microbial ecosystems. (shrink)

Exceptionally preserved fossils are the product of complex interplays of biological and geological processes including burial, autolysis and microbial decay, authigenic mineralization, diagenesis, metamorphism, and finally weathering and exhumation. Determining which tissues are preserved and how biases affect their preservation pathways is important for interpreting fossils in phylogenetic, ecological, and evolutionary frameworks. Although laboratory decay experiments reveal important aspects of fossilization, applying the results directly to the interpretation of exceptionally preserved fossils may overlook the impact of other key processes that (...) remove or preserve morphological information. Investigations of fossils preserving non-biomineralized tissues suggest that certain structures that are decay resistant are rarely preserved, and decay-prone structures can fossilize, albeit rarely. As we review here, decay resistance is an imperfect indicator of fossilization potential, and a suite of biological and geological processes account for the features preserved in exceptional fossils. Organisms decayed experimentally in seawater have been used as direct analogs for soft-bodied fossil taxa, with fossils representing a snapshot of a particular stage of decay. We argue that numerous geological and biological processes account for fossilization and that all of these should be considered when reconstructing extinct organisms. (shrink)

Exceptionally preserved fossils are the product of complex interplays of biological and geological processes including burial, autolysis and microbial decay, authigenic mineralization, diagenesis, metamorphism, and finally weathering and exhumation. Determining which tissues are preserved and how biases affect their preservation pathways is important for interpreting fossils in phylogenetic, ecological, and evolutionary frameworks. Although laboratory decay experiments reveal important aspects of fossilization, applying the results directly to the interpretation of exceptionally preserved fossils may overlook the impact of other key processes that (...) remove or preserve morphological information. Investigations of fossils preserving non-biomineralized tissues suggest that certain structures that are decay resistant are rarely preserved, and decay-prone structures can fossilize, albeit rarely. As we review here, decay resistance is an imperfect indicator of fossilization potential, and a suite of biological and geological processes account for the features preserved in exceptional fossils. Organisms decayed experimentally in seawater have been used as direct analogs for soft-bodied fossil taxa, with fossils representing a snapshot of a particular stage of decay. We argue that numerous geological and biological processes account for fossilization and that all of these should be considered when reconstructing extinct organisms. (shrink)

Compared to our understanding of positive prediction error signals occurring due to unexpected reward outcomes, less is known about the neural circuitry in humans that drives negative prediction errors during omission of expected rewards. While classical learning theories such as Rescorla–Wagner or temporal difference learning suggest that both types of prediction errors result from a simple subtraction, there has been recent evidence suggesting that different brain regions provide input to dopamine neurons which contributes to specific components of this prediction error (...) computation. Here, we focus on the brain regions responding to negative prediction error signals, which has been well-established in animal studies to involve a distinct pathway through the lateral habenula. We examine the activity of this pathway in humans, using a conditioned inhibition paradigm with high-resolution functional MRI. First, participants learned to associate a sensory stimulus with reward delivery. Then, reward delivery was omitted whenever this stimulus was presented simultaneously with a different sensory stimulus, the conditioned inhibitor. Both reward presentation and the reward-predictive cue activated midbrain dopamine regions, insula and orbitofrontal cortex. While we found significant activity at an uncorrected threshold for the CI in the habenula, consistent with our predictions, it did not survive correction for multiple comparisons and awaits further replication. Additionally, the pallidum and putamen regions of the basal ganglia showed modulations of activity for the inhibitor that did not survive the corrected threshold. (shrink)

The conceptions of jealousy used by philosophical writers are various, and, this paper suggests, largely inadequate. In particular, the difference between jealousy and envy has not yet been plausibly specified. This paper surveys some past analyses of this distinction and addresses problems with them, before proposing its own positive account of jealousy, developed from an idea of Leila Tov-Ruach(a.k.a. A. O. Rorty). Three conditions for being jealous are proposed and it is shownhow each of them helps to tell the emotion (...) apart from some distinct species of envy.It is acknowledged that the referents of the two terms are, to some extent, overlapping,but shown how this overlap is justified by the psychologies of the respective emotions. (shrink)

Spiritual energy and power can be purposefully used to create structures and conditions that allow religious communities to co-exist. In the context of South Asia and particularly of India, can the very presence of Christians become a gift to the community? A useful pointer could be revisiting the concept of Jubilee Year as described in Leviticus, Isaiah and Luke that portrays the message of atonement, restoration, hospitality and renewal of the divine covenant - all of which are essential for (...) inter-religious dialogue. The following paper seeks possible answers by addressing the concerns of the Christian layman and building up a framework for inter-religious dialogue, with a focus on being faithful to the Christian Gospel. The aim is to create conditions in which different accounts of the world of human experience can flourish together. (shrink)

This collection offers an extensive framework of comparative and individual studies assessing the place of Luke-Acts in the historiography of ancient Judaism and the Greco-Roman world, whilst also examining further developments in early Christian historiography up to Eusebius and Theodoret. Additional contributions concentrate on systematic questions concerning the literary genre and conception of Luke-Acts.

Molinism, formerly an invective, is nowadays a topic of philosophy. This book, however, does not deal with the modern renaissance of Middle Knowledge, rather, it explores its proliferation during the 17th and 18th centuries. The focus shifts from reviewing current trends in Church History to rehearsing the metaphysics that backed up Middle Knowledge. Fact, in Molinism, is threefold: It could have been otherwise, it belongs to some possible world, it is necessarily known by the Omniscient. Whereas the classical account of (...) God's foreknowledge rests on its being postvolitional, the Molinist qualification of this account denies that it applies to the counterfactuals. On what else then does it prevolitionally depend that God knows for sure something to happen rather than not to happen? The Salmantine Treatise on God's foreknowledge edited here provides some additional piece of evidence of a deep Molinist disagreement. Though the manuscript was ready for print in 1653, this business failed and the manuscript fell into oblivion along with its author. The Jesuit Luke Wadding (1593-1651) belongs to a number of men from Waterford who at a time, when intolerance forced Catholics into large scale emigration, hopefully turned towards Spain. He must not be confounded with his famous namesake, the Franciscan friar, who was his cousin. (shrink)

Since its introduction to China at the end of 1970s, Bourdieu’s sociological thinking has produced wide-ranging and profound effect on China’s educational researchers, with in-depth studies increas...

The unity of consciousness has so far been studied only as a relation holding among the many experiences of a single subject. I investigate whether this relation could hold between the experiences of distinct subjects, considering three major arguments against the possibility of such ‘between-subjects unity’. The first argument, based on the popular idea that unity implies subsumption by a composite experience, can be deflected by allowing for limited forms of ‘experience-sharing’, in which the same token experience belongs to more (...) than one subject. The second argument, based on the phenomenological claim that unified experiences have interdependent phenomenal characters, I show to rest on an equivocation. Finally, the third argument accuses between-subjects unity of being unimaginable, or more broadly a formal possibility corresponding to nothing we can make sense of. I argue that the familiar experience of perceptual co-presentation gives us an adequate phenomenological grasp on what between-subjects unity might be like. (shrink)

It is widely agreed that living kidney donation is permitted but living kidney sales are not. Call this the Received View. One way to support the Received View is to appeal to a particular understanding of the conditions under which living kidney transplantation is permissible. It is often claimed that donors must act altruistically, without the expectation of payment and for the sake of another. Call this the Altruism Requirement. On the conventional interpretation, the Altruism Requirement is a moral fact. (...) It states a legitimate constraint on permissible transplantation and is accepted on the basis of cogent argument. The present paper offers an alternative interpretation. I suggest the Altruism Requirement is a moral fiction—a kind of motivated falsehood. It is false that transplantation requires altruism. But the Requirement serves a purpose. Accepting it allows kidney donation but not kidney sale. It, in short, rationalizes the Received View. (shrink)

I address a question in moral metaphysics: How are conflicts between moral obligations possible? I begin by explaining why we cannot give a satisfactory answer to this question simply by positing that such conflicts are conflicts between rules, principles, or reasons. I then develop and defend the “Dispositional Account,” which posits that conflicts between moral obligations are conflicts between the manifestations of obligating dispositions (obligating powers, capacities, etc.), just as conflicts between physical forces are conflicts between the manifestations of (certain) (...) causal dispositions (causal powers, capacities, etc.). This account combines the so-called “moral forces” interpretation of prima facie obligations with a dispositional moral metaphysic according to which the metaphysical grounds of moral obligations are not rules or laws, but rather real, irreducibly dispositional properties (or powers) of moral agents and patients. My principal aims are to offer a theoretically attractive and suitably metaphysical account of conflicts of obligation, and to show that the dispositional moral metaphysic that grounds the Dispositional Account can explain and accommodate plausible normative views that rule- and law-based alternatives cannot, as well as to answer objections that have been pressed against other accounts of moral conflict (especially Ross’s) that appeal to moral dispositions or forces. (shrink)

A new formulation of the Fine-Tuning Argument (FTA) for the existence of God is offered, which avoids a number of commonly raised objections. I argue that we can and should focus on the fundamental constants and initial conditions of the universe, and show how physics itself provides the probabilities that are needed by the argument. I explain how this formulation avoids a number of common objections, specifically the possibility of deeper physical laws, the multiverse, normalisability, whether God would fine-tune at (...) all, whether the universe is too fine-tuned, and whether the likelihood of God creating a life-permitting universe is inscrutable. (shrink)

I analyse the meaning of a popular idiom among consciousness researchers, in which an individual's consciousness is described as a 'field'. I consider some of the contexts where this idea appears, in particular discussions of attention and the unity of consciousness. In neither case, I argue, do authors provide the resources to cash out all the implications of field-talk: in particular, they do not give sense to the idea of conscious elements being arrayed along multiple dimensions. I suggest ways to (...) extend and generalize the attentional construal of 'field-talk' to provide a genuine multiplicity of dimensions, through the notions of attentional proximity and causal proximity: the degree to which two experiential elements are disposed to bring one another into attention when attended, or to interact in other distinctively mental ways. I conclude that if consciousness is a field, it is one organized by attentional and/or causal proximity. (shrink)

Background: Transgender health care is a subject of much debate among clinicians, political commentators, and policy-makers. While the World Professional Association of Transgender Health (WPATH) Standards of Care (SOC) establish clinical standards, these standards contain implied ethics but lack explicit focused discussion of ethical considerations in providing care. An ethics chapter in the SOC would enhance clinical guidelines. Aims: We aim to provide a valuable guide for healthcare professionals, and anyone interested in the ethical aspects of clinical support for gender (...) diverse and transgender people of all ages. Recognizing that the WPATH is a global association, we address broad challenges. We offer a reflection on general ethical principles, providing conceptual tools for healthcare providers, patients, and families to navigate the specific challenges they might encounter in transgender health care, in line with WPATH’s worldwide mission and scope. Method: This article employs a descriptive analysis, and our framework of reference is the four principles of biomedical ethics: respect for autonomy, beneficence, nonmaleficence, and justice. Results: The article presents a discussion on the four ethical principles as applied to transgender health care. We address issues such as respect for patient autonomy in decision-making, the role of beneficence and nonmaleficence in clinical interventions, and the importance of justice in equitable treatment and access to care. Some of the ethical concerns we address in this article pertain to the current sociopolitical climate, where there has been increasing legal interference, internationally, for transgender and nonbinary people, particularly youth, seeking medical care. Discussion: We highlight the interplay between ethical principles and clinical practice, underscoring the need for ethical guidance in addressing the diverse challenges faced by healthcare providers and patients in transgender health care. We advocate for continuous refinement of ethical thinking to ensure that transgender health care is not only medically effective but also ethically sound. (shrink)

Recent research on the evolution of religion has focused on whether religion is an unselected by-product of evolutionary processes or if it is instead an adaptation by natural selection. Adaptive hypotheses for religion include direct fitness benefits from improved health and indirect fitness benefits mediated by costly signals and/or cultural group selection. Herein, I propose that religious denominations achieve indirect fitness gains for members through the use of ecologically arbitrary beliefs, rituals, and moral rules that function as recognition markers of (...) cultural inheritance analogous to kin and species recognition of genetic inheritance in biology. This recognition signal hypotheses could act in concert with either costly signaling or cultural group selection to produce evolutionarily altruistic behaviors within denominations. Using a cultural phylogenetic analysis, I show that a large set of religious behaviors among extant Christian denominations supports the prediction of the recognition signal hypothesis that characters change more frequently near historical schisms. By incorporating demographic data into the model, I show that more-distinctive denominations, as measured through dissimilar characteristics, appear to be protected from intrusion by nonmembers in mixed-denomination households, and that they may be experiencing greater biological growth of their populations even in the present day. (shrink)

Chalmers (2002) argues against physicalism in part using the premise that no truth about consciousness can be deduced a priori from any set of purely structural truths. Chalmers (2012) elaborates a detailed definition of what it is for a truth to be structural, which turns out to include spatiotemporal truths. But Chalmers (2012) then proposes to define spatiotemporal terms by reference to their role in causing spatial and temporal experiences. Stoljar (2015) and Ebbers (Ms) argue that this definition of spatiotemporal (...) terms allows for the trivial falsification of Chalmers (2002)’s premise about structure and consciousness. I show that this result can be avoided by tweaking the relevant premise, and moreover that this tweak is well-motivated and not ad hoc. (shrink)

Polyamory is a form of consensual non-monogamy. To render it palatable to critics, activists and theorists often accentuate its similarity to monogamy. I argue that this strategy conceals the distinctive character of polyamorous intimacy. A more discriminating account of polyamory helps me answer objections to the lifestyle whilst noting some of its unique pitfalls. I define polyamory, and explain why people pursue this lifestyle. Many think polyamory is an inferior form of intimacy; I describe four of their main objections. I (...) explain how commitment to ‘the polyamorous possibility’ prompts one to viscerally experience personal, practical, and social constraints. Unlike monogamous dynamics, these confrontations are mediated by third parties who destabilise the familiar dynamics of coupled life. Polyamory can be emotionally challenging but, as I outline in the article, it is sustained by interpersonal emotional work that helps people feel and understand their emotions, communicate without confrontation, and contain the difficult emotions of others. This work is qualitatively and quantitatively intensified in polyamory. Finally, I rebut objections to polyamory whilst also acknowledging the ways polyamory has its own pitfalls. (shrink)

Fine-tuning in physics and cosmology is often used as evidence that a theory is incomplete. For example, the parameters of the standard model of particle physics are “unnaturally” small, which has driven much of the search for physics beyond the standard model. Of particular interest is the fine-tuning of the universe for life, which suggests that our universe’s ability to create physical life forms is improbable and in need of explanation, perhaps by a multiverse. This claim has been challenged on (...) the grounds that the relevant probability measure cannot be justified because it cannot be normalized, and so small probabilities cannot be inferred. We show how fine-tuning can be formulated within the context of Bayesian theory testing in the physical sciences. The normalizability problem is seen to be a general problem for testing any theory with free parameters, and not a unique problem for fine-tuning. Physical theories in fact avoid such problems in one of two ways. Dimensional parameters are bounded by the Planck scale, avoiding troublesome infinities, and we are not compelled to assume that dimensionless parameters are distributed uniformly, which avoids non-normalizability. (shrink)

This paper focuses on Honig’s critical reworking of the concept of inclination and her concept of “slow regicide”. With “slow regicide” Honig describes a performative critique of the violence of the patriarchal order. However, what Honig underestimates, I argue, is that this intervention must itself be non-violent if it is not to reinstate patriarchal violence. My suggestion is that paying closer attention to the performativity of inclination shows how “slow regicide” enables a non-violent refusal in which the normativity of patriarchy (...) is frustrated and fails. (shrink)

Although the seasons have been a perennial theme in literature and art, their significance for philosophy and environmental theory has remained largely unexplored. This pioneering book demonstrates the ways in which inquiry into the seasons reveals new and illuminating perspectives for philosophy, environmental thought, anthropology, cultural studies, aesthetics, poetics, and literary criticism. The Seasons opens up new avenues for research in these fields and provides a valuable resource for teachers and students of the environmental humanities. The innovative essays herein address (...) a wide range of seasonal cultures and geographies, from the traditional Western model of the four seasons––spring, summer, fall, and winter––to the Indigenous seasons of Australia and the Arctic. Exemplifying the crucial importance of interdisciplinary research, The Seasons makes a compelling case for the relevance of the seasons to our daily lives, scientific understanding, diverse cultural practices, and politics. (shrink)

Two main types of philosophical arguments have been given in support of the claim that the citizens of affluent societies have stringent moral duties to aid the global poor: “positive duty” arguments based on the notion of beneficence and “negative duty” arguments based on noninterference. Peter Singer’s positive duty argument (Singer 1972) and Thomas Pogge’s negative duty argument (Pogge 2002) are among the most prominent examples. Philosophers have made speculative claims about the relative effectiveness of these arguments in promoting attitudes (...) and behaviors that could lead to the alleviation of poverty. In this article we present the results of two empirical studies that evaluate these claims, and suggest that both arguments have a modest effect on people’s attitudes and behaviors regarding global poverty. In a replication of the second study, the negative duty argument, in particular, had a statistically significant effect on donations. We discuss the theoretical and practical significance of these results and suggest directions for further research on the role that philosophical arguments can play in engendering concern and action on pressing moral problems. (shrink)

The best arguments against gun control invoke moral rights—it might be good if there were fewer guns in circulation, but there is a moral right to own firearms. Rather than emphasizing the potential benefits of gun control, this paper meets the best arguments on their home turf. I argue that there simply is no moral right to keep guns on one’s person or in one’s residence. In fact, our moral rights support the mutual disarmament of citizens and police.

Studies of animal culture have not normally included a consideration of cetaceans. However, with several long-term field studies now maturing, this situation should change. Animal culture is generally studied by either investigating transmission mechanisms experimentally, or observing patterns of behavioural variation in wild populations that cannot be explained by either genetic or environmental factors. Taking this second, ethnographic, approach, there is good evidence for cultural transmission in several cetacean species. However, only the bottlenose dolphin (Tursiops) has been shown experimentally to (...) possess sophisticated social learning abilities, including vocal and motor imitation; other species have not been studied. There is observational evidence for imitation and teaching in killer whales. For cetaceans and other large, wide-ranging animals, excessive reliance on experimental data for evidence of culture is not productive; we favour the ethnographic approach. The complex and stable vocal and behavioural cultures of sympatric groups of killer whales (Orcinus orca) appear to have no parallel outside humans, and represent an independent evolution of cultural faculties. The wide movements of cetaceans, the greater variability of the marine environment over large temporal scales relative to that on land, and the stable matrilineal social groups of some species are potentially important factors in the evolution of cetacean culture. There have been suggestions of gene-culture coevolution in cetaceans, and culture may be implicated in some unusual behavioural and life-history traits of whales and dolphins. We hope to stimulate discussion and research on culture in these animals. (shrink)

The intent of this essay is to examine what most would call an essential component to the theistic notion of a perfected agent in heaven: impeccability. In Part 1 I will attempt to softly defend the Christian dependence on the doctrine of impeccability, followed by an examination of what I believe to be the two basic moral conditions for impeccability: the deontic condition and the virtue condition. In Parts 2 and 3, I will examine the coherence of each of these (...) conditions by proposing recently raised objections to both. Ultimately, my hope for this essay is to further the discussion concerning the theistic notions of a perfected agent, and the coherence of a heavenly afterlife for that perfected agent. (shrink)

Kant distinguishes between ‘active’ and ‘passive’ citizens and holds that only the former are civilly self-sufficient and possess rights of political participation. Such rights are important, since for Kant state institutions are a necessary condition for individual freedom. Thus, only active citizens are entitled to contribute to a necessary condition for the freedom of each. I argue that Kant attributes civil self-sufficiency to those who are not under the authority of any private individual for their survival. This reading is more (...) textually grounded than the dominant reading, which understands civil self-sufficiency in terms of economic relations alone. I further argue that Kant was interested in relations of authority because he was concerned to eliminate certain forms of corruption. This indicates that Kant’s contested distinction between active and passive citizens was a response to a key problem of any account of public lawgiving. (shrink)

This article responds to Tim Hsiao's "The Moral Case for Gun Ownership".

Asexuality is overlooked in the philosophical literature and in wider society. Such neglect produces incomplete or inaccurate accounts of romantic life and harms asexual people. We develop an account of asexuality to redress this neglect and enrich discussion of romantic life. Asexual experiences are diverse. Some asexual people have sex; some have romantic relationships in the absence of sex. We accept the common definition of asexuality as the absence of sexual attraction and explain how sexual attraction and sexual desire differ (...) by giving an affordance‐like account of sexual attraction. Armed with that distinction, we show that asexuality is clearly different from celibacy or disorders of desire and that some existing philosophical theories of sexual desire struggle to accommodate asexual sexuality. We then build on asexual testimony about the diversity of non‐sexual attractions to answer two common objections levelled at asexual romance: that romantic relationships require sexual attraction or that sex in the absence of sexual attraction is insufficiently focused on someone as an individual. Finally, we describe some of the ways asexuality has been erased or denigrated in society, and the specific injustices and harms that result. (shrink)

This article discusses five attempts at justifying the provision of welfare on Kantian grounds. I argue that none of the five proposals is satisfactory. Each faces a serious challenge on textual or systematic grounds. The conclusion to draw from this is not that a Kantian cannot defend the provision of welfare. Rather, the conclusion to draw is that the task of defending the provision of welfare on Kantian grounds is a difficult one whose success we should not take for granted.

A historical investigation of the exclusion of Africa and Asia from modern histories of philosophy.

Philosophical exploration of individualism and externalism in the cognitive sciences most recently has been focused on general evaluations of these two views (Adams & Aizawa 2008, Rupert 2008, Wilson 2004, Clark 2008). Here we return to broaden an earlier phase of the debate between individualists and externalists about cognition, one that considered in detail particular theories, such as those in developmental psychology (Patterson 1991) and the computational theory of vision (Burge 1986, Segal 1989). Music cognition is an area in the (...) cognitive sciences that has received little attention from philosophers, though it has relatively recently been thrown into the externalist spotlight (Cochrane 2008, Kruger 2014, Kersten forthcoming). Given that individualism can be thought of as a kind of paradigm for research on cognition, we provide a brief overview of the field of music cognition and individualistic tendencies within the field (sections 2 and 3) before turning to consider externalist alternatives to individualistic paradigms (section 4-5) and then arguing for a qualified form of externalism about music cognition (section 6). (shrink)

This chapter takes the form of a discussion between the editors of this volume and Steven Lukes, one the most eminent critics of methodological individualism. The focus is on Lukes’ interpretation of methodological individualism in terms of linguistic exclusivism (i.e., naive reductionism), the multiple-realization problem, Boudon’s and Elster’s micro-foundationalist approach, ontological individualism, and the rationality of human action.