Results for 'Hardy-Weinberg principle'

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  1. Constitutive elements in science beyond physics: the case of the HardyWeinberg principle.Michele Luchetti - 2018 - Synthese (Suppl 14):3437-3461.
    In this paper, I present a new framework supporting the claim that some elements in science play a constitutive function, with the aim of overcoming some limitations of Friedman's (2001) account. More precisely, I focus on what I consider to be the gradualism implicit in Friedman's interpretation of the constitutive a priori, that is, the fact that it seems to allow for degrees of 'constitutivity'. I tease out such gradualism by showing that the constitutive character Friedman aims to track can (...)
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  2.  41
    Rethinking HardyWeinberg and genetic drift in undergraduate biology.Joanna Masel - 2012 - Bioessays 34 (8):701-710.
    Population genetics is often taught in introductory biology classes, starting with the HardyWeinberg principle (HWP) and genetic drift. Here I argue that teaching these two topics first aligns neither with current expert knowledge, nor with good pedagogy. Student difficulties with mathematics in general, and probability in particular, make population genetics difficult to teach and learn. I recommend an alternative, historically inspired ordering of population genetics topics, based on progressively increasing mathematical difficulty. This progression can facilitate just‐in‐time math (...)
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  3. Scientific Coordination beyond the A Priori: A Three-dimensional Account of Constitutive Elements in Scientific Practice.Michele Luchetti - 2020 - Dissertation, Central European University
    In this dissertation, I present a novel account of the components that have a peculiar epistemic role in our scientific inquiries, since they contribute to establishing a form of coordination. The issue of coordination is a classic epistemic problem concerning how we justify our use of abstract conceptual tools to represent concrete phenomena. For instance, how could we get to represent universal gravitation as a mathematical formula or temperature by means of a numerical scale? This problem is particularly pressing when (...)
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  4.  21
    A logic for arguing about probabilities in measure teams.Tapani Hyttinen, Gianluca Paolini & Jouko Väänänen - 2017 - Archive for Mathematical Logic 56 (5-6):475-489.
    We use sets of assignments, a.k.a. teams, and measures on them to define probabilities of first-order formulas in given data. We then axiomatise first-order properties of such probabilities and prove a completeness theorem for our axiomatisation. We use the HardyWeinberg Principle of biology and the Bell’s Inequalities of quantum physics as examples.
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  5.  50
    Explanation and the Evolutionary First Law.Devin Y. Gouvêa - 2015 - Philosophy of Science 82 (3):363-382.
    Analogies between Newtonian mechanics and evolutionary processes are powerful but not infinitely versatile tools for generating explanations of particular biological phenomena. Their explanatory range is sensitive to a preliminary decision about which processes count as background conditions and which as special forces. Here I argue that the defenders of the zero-force evolutionary law are mistaken in defending their decision as the only appropriate one. The HardyWeinberg principle remains a viable option that is consistent with the epistemic role (...)
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  6.  36
    Evolutionary forces and the HardyWeinberg equilibrium.Eugene Earnshaw - 2015 - Biology and Philosophy 30 (3):423-437.
    The HardyWeinberg equilibrium has been argued by Sober, Stephens and others to represent the zero-force state for evolutionary biology understood as a theory of forces. I investigate what it means for a model to involve forces, developing an explicit account by defining what the zero-force state is in a general theoretical context. I use this account to show that HardyWeinberg equilibrium is not the zero-force state in biology even in the contexts in which it applies, and (...)
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  7. Gravitation and cosmology: principles and applications of the general theory of relativity.Steven Weinberg - 1972 - New York,: Wiley.
    Weinberg's 1972 work, in his description, had two purposes. The first was practical to bring together and assess the wealth of data provided over the previous decade while realizing that newer data would come in even as the book was being printed. He hoped the comprehensive picture would prepare the reader and himself to that new data as it emerged. The second was to produce a textbook about general relativity in which geometric ideas were not given a starring role (...)
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  8. A Straightforward Multiallelic Significance Test for the Hardy-Weinberg Equilibrium Law.Julio Michael Stern, Marcelo de Souza Lauretto, Fabio Nakano, Silvio Rodrigues Faria & Carlos Alberto de Braganca Pereira - 2009 - Genetics and Molecular Biology 32 (3):619-625.
    Much forensic inference based upon DNA evidence is made assuming Hardy-Weinberg Equilibrium (HWE) for the genetic loci being used. Several statistical tests to detect and measure deviation from HWE have been devised, and their limitations become more obvious when testing for deviation within multiallelic DNA loci. The most popular methods-Chi-square and Likelihood-ratio tests-are based on asymptotic results and cannot guarantee a good performance in the presence of low frequency genotypes. Since the parameter space dimension increases at a quadratic (...)
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  9.  60
    What is the Status of the Hardy-Weinberg Law within Population Genetics?Pablo Lorenzano - 2014 - Vienna Circle Institute Yearbook 17:159-172.
    The aim of this paper is to further develop van Fraassen’s diagnosis, expanding a previous analysis of the fundamental law of classical genetics and the status of the so-called ‘Mendel’s laws’.6 According to this diagnosis the Hardy-Weinberg law: 1) cannot be considered as axiom (or fundamental law) for classical population genetics, since it is a law that describes an equilibrium that 2) holds only under certain special conditions, and 3) only determines a subclass of models, 4) whose generalized (...)
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  10.  5
    The Rise of Particulars: AI and the Ethics of Care.David Weinberger - 2024 - Philosophies 9 (1):26.
    Machine learning (ML) trains itself by discovering patterns of correlations that can be applied to new inputs. That is a very powerful form of generalization, but it is also very different from the sort of generalization that the west has valorized as the highest form of truth, such as universal laws in some of the sciences, or ethical principles and frameworks in moral reasoning. Machine learning’s generalizations synthesize the general and the particular in a new way, creating a multidimensional model (...)
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  11.  68
    Bas Van Fraassen y la Ley de Hardy-Weinberg: una discusión y desarrolo de su diagnóstico.Pablo Lorenzano - 2008 - Principia: An International Journal of Epistemology 12 (2):121-154.
    The aim of this article is to discuss and develop the diagnose of the Hardy-Weinberg law made by van Fraassen (1987, p. 110), according to which: 1) that law cannot be considered a law used as an axiom for the classical population genetics as a whole, since it is an equilibrium-law that holds only under certain special conditions; 2) it just determines a subclass of models; 3) its generalization shades off into logical vacuity; and 4) more complex variants (...)
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  12.  27
    Kant's principle of personality.Hardy E. Jones - 1971 - Madison,: University of Wisconsin Press.
    Revision of the author's thesis, University of Wisconsin, 1970. Bibliography: p. 155-158.
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  13. What's epistemology for? The case for neopragmatism in normative metaepistemology.Jonathan M. Weinberg - 2006 - In Stephen Cade Hetherington (ed.), Epistemology futures. New York: Oxford University Press. pp. 26--47.
    How ought we to go about forming and revising our beliefs, arguing and debating our reasons, and investigating our world? If those questions constitute normative epistemology, then I am interested here in normative metaepistemology: the investigation into how we ought to go about forming and revising our beliefs about how we ought to go about forming and revising our beliefs -- how we ought to argue about how we ought to argue. Such investigations have become urgent of late, for the (...)
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  14.  21
    Are fundamental moral principles incapable of proof?Hardy Jones - 1979 - Metaphilosophy 10 (2):153–160.
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  15. Genuine Bayesian Multiallelic Significance Test for the Hardy-Weinberg Equilibrium Law.Julio Michael Stern, Carlos Alberto de Braganca Pereira, Fabio Nakano & Martin Ritter Whittle - 2006 - Genetics and Molecular Research 5 (4):619-631.
    Statistical tests that detect and measure deviation from the Hardy-Weinberg equilibrium (HWE) have been devised but are limited when testing for deviation at multiallelic DNA loci is attempted. Here we present the full Bayesian significance test (FBST) for the HWE. This test depends neither on asymptotic results nor on the number of possible alleles for the particular locus being evaluated. The FBST is based on the computation of an evidence index in favor of the HWE hypothesis. A great (...)
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  16.  26
    Mill's argument for the principle of utility.Hardy Jones - 1978 - Philosophy and Phenomenological Research 38 (3):338-354.
  17.  7
    Prudence, Impartiality, and the Principle of Utility.Hardy Jones - 1981 - Pacific Philosophical Quarterly 62 (2):193-202.
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  18.  63
    The practicality of political philosophy.Justin Weinberg - 2013 - Social Philosophy and Policy 30 (1-2):330-351.
    Must principles of justice be practical? Some political philosophers, the “implementers,” say yes. Others, the “idealists,” say no. Despite this disagreement, the implementers and idealists agree on what “practical” means, subscribing to the “implementation-prediction” conception of practicality. They also seem to agree that principles of so-called “ideal theory” need not be IP-practical. The implementers take this as a reason to reject ideal theory as an approach to principles of justice, while the idealists do not. In this paper, I argue that (...)
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  19. Atoms and Monads: An Inquiry Into the Idea of Nature in Locke's "Essay" and Leibniz's "New Essays".Sue M. Weinberg - 1985 - Dissertation, City University of New York
    A matter of significance for the history of philosophy is the question of what are the issues that underlie Leibniz's response to Locke's Essay Concerning Human Understanding, in his own New Essays on Human Understanding. Exploration of that question can contribute to interpretations of both Locke and Leibniz. Equally important, it can provide insight into problems of philosophy that have their genesis in the seventeenth century. ;The dissertation uses the Essay and the New Essays to explore what it regards as (...)
     
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  20. Existence: Who needs it? The non‐identity problem and merely possible people.Rivka Weinberg - 2012 - Bioethics 27 (9):471-484.
    In formulating procreative principles, it makes sense to begin by thinking about whose interests ought to matter to us. Obviously, we care about those who exist. Less obviously, but still uncontroversially, we care about those who will exist. Ought we to care about those who might possibly, but will not actually, exist? Recently, unusual positions have been taken regarding merely possible people and the non-identity problem. David Velleman argues that what might have happened to you – an existent person – (...)
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  21.  39
    Acting on Principle: an essay on Kantian Ethics.Hardy Jones - 1977 - International Studies in Philosophy 9:222-223.
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  22.  94
    The Risk of a Lifetime: How, When, and Why Procreation May Be Permissible.Rivka Weinberg - 2015 - New York, US: Oxford University Press USA.
    Having children is probably as old as the first successful organism. It is often done thoughtlessly. This book is an argument for giving procreating some serious thought, and a theory of how, when, and why procreation may be permissible.Rivka Weinberg begins with an analysis of the kind of act procreativity is and why we might be justifiably motivated to engage in it. She then proceeds to argue that, by virtue of our ownership and control of the hazardous material that (...)
  23.  73
    Norms and the Agency of Justice.Justin Weinberg - 2009 - Analyse & Kritik 31 (2):319-338.
    In this paper I argue that when thinking about justice, political philosophers should pay more attention to social norms, not just the usual subjects of basic principles, rights, laws, and policies. I identify two widely-endorsed ideas about political philosophy that interfere with recognizing the importance of social norms—ideas I dub ‘compulsoriness’ and ‘institutionalism’—and argue for their rejection. I do this largely by focusing on questions about who can and should be an agent of justice. I argue that careful reflection on (...)
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  24. Evidence-Based Policy: A Practical Guide to Doing it Better, Nancy Cartwright and Jeremy Hardie. Oxford University Press, 2013, ix + 196 pages. [REVIEW]Naftali Weinberger - 2014 - Economics and Philosophy 30 (1):113-120.
  25.  7
    Ethical Principles for Social Philosophy. [REVIEW]David Weinberger - 1985 - Idealistic Studies 15 (1):83-84.
    According to John Howie, who compiled these first six annual Wayne Leys Memorial Lectures, “These essays invite the reader to discover the relevance of clearly stated, balanced, and reasonable ethical principles to controversial issues of our time.” Although the essays are indeed clearly stated, balanced, and reasonable, it is unlikely the book’s purchasers will be discovering for the first time that philosophy has something to say about social issues. But an anthology such as this will be bought and appreciated by (...)
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  26.  1
    Medical ethics: applying theories and principles to the patient encounter.Matt Weinberg (ed.) - 2001 - Amherst, N.Y.: Prometheus Books.
    While dramatic medical "breakthroughs" routinely grab headlines, health-care providers know their daily lives center much more frequently on mundane issues that the media ignore, such as how doctors and their patients can form more trusting relationships. This anthology for health-care providers and ethics committee members focuses on just such questions. Essays are divided under headings including care at the end of life; patients, families, and health-care decisions; health law; care for severely compromised newborns; issues in transplantation, managed care, resource allocation, (...)
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  27.  46
    The Theory of Legal Dynamics Reconsidered.Ota Weinberger - 1991 - Ratio Juris 4 (1):18-35.
    The author criticizes Kelsen's distinction between static and dynamic systems of norms and his theory of legal dynamics. The author moreover presents the institutionalist conception of legal dynamics. Kelsen's concept of static systems is incompatible with normological scepticism: The deduction of rules from a basic principle depends on additional premises; even in static systems there is a kind of dynamics produced by actual facts. Kelsen's conception of legal dynamics is also incompatible with normological scepticism and with Kelsen's demand of (...)
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  28. Kant's Principle of Personality.Hardy E. Jones - 1974 - Mind 83 (332):610-611.
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  29. Science, Expertise, and Democracy.Justin Weinberg & Kevin C. Elliott - 2012 - Kennedy Institute of Ethics Journal 22 (2):83-90.
    The combination of government’s significant involvement in science, science’s significant effects on the public, and public ignorance raise important challenges for reconciling scientific expertise with democratic governance. Nevertheless, there have recently been a variety of encouraging efforts to make scientific activity more responsive to social values and to develop citizens’ capacity to engage in more effective democratic governance of science. This essay introduces a special issue of the Kennedy Institute of Ethics Journal on “Science, Expertise, and Democracy,” consisting of five (...)
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  30.  44
    The Role of Rules.Ota Weinberger - 1988 - Ratio Juris 1 (3):224-240.
    . The author conceives rules as action‐determining ideas. They are general and of hypothetical form, and they are of three semantic types: descriptive, technological, and normative rules. The most important categorisation of normative rules is the distinction between rules of behaviour and power‐conferring rules. Both kinds of rules are necessary to establish institutions. Principles are a special kind of normative rules. The social existence of normative rules is connected with their institutionalisation as frames for action. The dynamics of rules is (...)
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  31. Thinking about the Liar, Fast and Slow.Robert Barnard, Joseph Ulatowski & Jonathan Weinberg - 2017 - In Bradley P. Armour-Garb (ed.), Reflections on the Liar. Oxford, England: Oxford University. pp. 39-70.
    The liar paradox is widely conceived as a problem for logic and semantics. On the basis of empirical studies presented here, we suggest that there is an underappreciated psychological dimension to the liar paradox and related problems, conceived as a problem for human thinkers. Specific findings suggest that how one interprets the liar sentence and similar paradoxes can vary in relation to one’s capacity for logical and reflective thought, acceptance of certain logical principles, and degree of philosophical training, but also (...)
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  32. Faithfulness, Coordination and Causal Coincidences.Naftali Weinberger - 2018 - Erkenntnis 83 (2):113-133.
    Within the causal modeling literature, debates about the Causal Faithfulness Condition have concerned whether it is probable that the parameters in causal models will have values such that distinct causal paths will cancel. As the parameters in a model are fixed by the probability distribution over its variables, it is initially puzzling what it means to assign probabilities to these parameters. I propose that to assign a probability to a parameter in a model is to treat that parameter as a (...)
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  33.  2
    Acting on Principle: an essay on Kantian Ethics. [REVIEW]Hardy Jones - 1977 - International Studies in Philosophy 9:222-223.
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  34.  10
    Prima Facie Ought. A Logical and Methodological Enquiry.Ota Weinberger - 1999 - Ratio Juris 12 (3):239-251.
    The pressing problem of prima facie validity must be treated on the basis of a differentiation of types of normative rules. Rules stating principles or purposes are always applied as views determining the decision by weighing (but not by subsumption) so that the problem of prima facie validity does not arise. Neither is there a problem of such a restricted form of validity concerning power‐conferring rules. The author shows that prima facie validity of rules of behaviour must not be treated (...)
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  35.  22
    Conflicting Views on Practical Reason. Against Pseudo‐Arguments in Practical Philosophy.Ota Weinberger - 1992 - Ratio Juris 5 (3):252-268.
    The author distinguishes two concepts of practical reason: (a) practical reason as a source of practical principles, and (b) practical reason as the theory of thought operations connected with action. He proves that there is no practical recognition in the sense (a). We can deal with actions only on the basis of dichotomic semantics. Critical analyses of some theories of practical reason are presented (Kant, Lorenzen, Apel, Alexy). The critical part of the paper mainly concerns the discourse theory and its (...)
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  36.  59
    Two uneliminated uses for “concepts”: Hybrids and guides for inquiry.Chad Gonnerman & Jonathan M. Weinberg - 2010 - Behavioral and Brain Sciences 33 (2-3):211-212.
    Machery's case against hybrids rests on a principle that is too strong, even by his own lights. And there are likely important generalizations to be made about hybrids, if they do exist. Moreover, even if there were no important generalizations about concepts themselves, the term picks out an important class of entities and should be retained to help guide inquiry.
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  37.  13
    The Politics of Ethics in Human Services: Dueling Discourses.Merlinda Weinberg - 2018 - Ethics and Behavior 28 (6):497-509.
    How ethics in human services is a political activity, shaping social relationships, is explored through the examination of two opposing discourses, a principle-based and a situated/relational narrative. Factors such as neo-liberalism, managerialism, and the risk-aversive society give a context for the reasons that the principle-based discourse has been the predominant influence, and what interests are served by this trope taking center stage. A delineation and critique of both perspectives are provided, including an explanation of the epistemological underpinnings of (...)
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  38.  12
    Nature’s Suit: Husserl’s Phenomenological Philosophy of the Physical Sciences.Lee Hardy - 2013 - Athens, Ohio: Ohio University Press.
    Edmund Husserl, founder of the phenomenological movement, is usually read as an idealist in his metaphysics and an instrumentalist in his philosophy of science. In _Nature’s Suit_, Lee Hardy argues that both views represent a serious misreading of Husserl’s texts. Drawing upon the full range of Husserl’s major published works together with material from Husserl’s unpublished manuscripts, Hardy develops a consistent interpretation of Husserl’s conception of logic as a theory of science, his phenomenological account of truth and rationality, (...)
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  39.  9
    Rigidity, Force and Physical Geometry.Carlton B. Weinberg - 1941 - Philosophy of Science 8 (4):506-532.
    From the desire to find support and confirmation for our personal sensory observations, and from the human interest in sharing our experiences with others, there emerges a basic principle of scientific method: We demand the possibility of intelligible communication and agreement concerning individuals' sensory perceptions in particular and their experiences in general. This requirement is made both for the natural and social sciences. The raw material offered for logical organization must be capable of exhibiting an inter-subjective character—such material, or (...)
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  40.  9
    Nature's Suit: Husserl's Phenomenological Philosophy of the Physical Sciences.Lee Hardy - 2013 - Athens, Ohio: Ohio University Press.
    Edmund Husserl, founder of the phenomenological movement, is usually read as an idealist in his metaphysics and an instrumentalist in his philosophy of science. In _Nature’s Suit_, Lee Hardy argues that both views represent a serious misreading of Husserl’s texts. Drawing upon the full range of Husserl’s major published works together with material from Husserl’s unpublished manuscripts, Hardy develops a consistent interpretation of Husserl’s conception of logic as a theory of science, his phenomenological account of truth and rationality, (...)
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  41. Procreative Justice: A Contractualist Approach.Rivka M. Weinberg - 2001 - Dissertation, University of Michigan
    My dissertation investigates the requirements of procreative justice. The procreative justice problem is that parents' interest in procreation conflicts with children's interest in optimal birth conditions. Intergenerational reciprocity is the principle that adjudicates this conflict: reciprocity dictates that children demand no more of their parents' procreative practices than they themselves are willing to abide by as adults and dig parents only procreate in accordance with principles dig they would have wanted their own parents to have followed. I develop a (...)
     
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  42.  13
    The Supremacy of Whiteness in Social Work Ethics.Merlinda Weinberg - 2022 - Ethics and Social Welfare 16 (4):347-363.
    This paper explores racism specifically as an ethical concern in the field of social work and queries why it has been insufficiently emphasised in the discursive frames on ethics. The minimisation of racism as an ethical issue is illustrated utilising two research studies with racialised practitioners who highlighted experiences of racism. Epistemologies of ignorance by dominant groups contribute to norms that maintain dominance. These epistemological failings, as exemplified in social work, are delineated. Additionally, the utilisation of codes of ethics, based (...)
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  43.  92
    A Philosophical Approach to Norm Logic.Ota Weinberger - 2001 - Ratio Juris 14 (1):130-141.
    The author outlines his views on the essence of philosophical logic. There are two means of philosophical argumentation: intuition and analysis of the problem situation under examination. Logical intuition can be replaced by improved intuition based on new intellectual constructions. Then the author explains—in opposition to von Wright—the main philosophical traits of his conception of norm logic. The structure of the information processing determining action justifies the application of dichotomous semantics in action theory and in practical philosophy. The theory of (...)
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  44.  15
    Rigidity, force and physical geometry.Carleton B. Weinberg - 1941 - Philosophy of Science 8 (4):506-532.
    From the desire to find support and confirmation for our personal sensory observations, and from the human interest in sharing our experiences with others, there emerges a basic principle of scientific method: We demand the possibility of intelligible communication and agreement concerning individuals' sensory perceptions in particular and their experiences in general. This requirement is made both for the natural and social sciences. The raw material offered for logical organization must be capable of exhibiting an inter-subjective character—such material, or (...)
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  45.  18
    The Language of Practical Philosophy.Ota Weinberger - 2002 - Ratio Juris 15 (3):283-293.
    Kant’s criticism is based on the idea that all possible knowledge of facts is determined by the immanent structure of our apparatus of cognition, and that therefore we have no access to reality as it is per se (“Ding an sich”). In modern analytical philosophy some elements of this view survived, namely, the distinction between framework construction and actual data of experience, supposition or voluntary setting. The conditio humana is characterised by our capacity of acting. Acting is defined as behaviour (...)
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  46.  9
    In search of Isaiah Berlin: a literary adventure.Henry Hardy - 2019 - London: Tauris Parke.
    Isaiah Berlin was one of the greatest thinkers of the twentieth century - a man who set ideas on fire. His defence of liberty and plurality was passionate and persuasive and inspired a generation. His ideas - especially his reasoned rejection of excessive certainty and political despotism - have become even more prescient and vital today.But who was the man behind such influential views? In Search of Isaiah Berlin tells the compelling story of a decades-long collaboration between Berlin and his (...)
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  47. Logical Bell Inequalities.Samson Abramsky & Lucien Hardy - 2012 - Physical Review A 85:062114-1 - 062114-11.
    Bell inequalities play a central role in the study of quantum nonlocality and entanglement, with many applications in quantum information. Despite the huge literature on Bell inequalities, it is not easy to find a clear conceptual answer to what a Bell inequality is, or a clear guiding principle as to how they may be derived. In this paper, we introduce a notion of logical Bell inequality which can be used to systematically derive testable inequalities for a very wide variety (...)
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  48.  46
    Bas Van Fraassen Y la Ley de Hardy-Weinberg.Pablo Lorenzano - forthcoming - Principia.
  49. The Frugal Inference of Causal Relations.Malcolm Forster, Garvesh Raskutti, Reuben Stern & Naftali Weinberger - 2018 - British Journal for the Philosophy of Science 69 (3):821-848.
    Recent approaches to causal modelling rely upon the causal Markov condition, which specifies which probability distributions are compatible with a directed acyclic graph. Further principles are required in order to choose among the large number of DAGs compatible with a given probability distribution. Here we present a principle that we call frugality. This principle tells one to choose the DAG with the fewest causal arrows. We argue that frugality has several desirable properties compared to the other principles that (...)
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  50. Puzzles for ZFEL, McShea and Brandon’s zero force evolutionary law.Martin Barrett, Hayley Clatterbuck, Michael Goldsby, Casey Helgeson, Brian McLoone, Trevor Pearce, Elliott Sober, Reuben Stern & Naftali Weinberger - 2012 - Biology and Philosophy 27 (5):723-735.
    In their 2010 book, Biology’s First Law, D. McShea and R. Brandon present a principle that they call ‘‘ZFEL,’’ the zero force evolutionary law. ZFEL says (roughly) that when there are no evolutionary forces acting on a population, the population’s complexity (i.e., how diverse its member organisms are) will increase. Here we develop criticisms of ZFEL and describe a different law of evolution; it says that diversity and complexity do not change when there are no evolutionary causes.
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