Research that is initiated, designed or funded by sponsor agencies based in countries with relatively high social and economic development, and conducted in countries that are relatively less developed, gives rise to many important ethical challenges. Although clinical trials of HIV vaccines began ten years ago in the US and Europe, an increasing number of trials are now being conducted or planned in other countries, including several that are considered “developing” countries. Safeguarding the rights and welfare of individuals participating as (...) research subjects in developing countries is a priority. In September, 1997, the Joint United Nations Programme on HIV/AIDS embarked on a process of international consultation; its purpose was further to define the important ethical issues and to formulate guidance that might facilitate the ethical design and conduct of HIV vaccine trials in international contexts. This paper summarises the major outcomes of the UNAIDS consultative process. (shrink)

In this study of the cognitive paradigm, De Mey applies the study of computer models of human perception to the philosophy and sociology of science. "A most stimulating, and intellectually delightful book."--John Goldsmith "[De Mey] has brought together an unusually wide range of material, and suggested some interesting lines of thought, about what should be an important application of cognitive science: The understanding of science itself."-- Cognition and Brain Theory "It ought to be on the shelf of every teacher and (...) researcher in the field and on the reading list of any student or practitioner seriously interested in how those they serve are likely to set about knowing."-- ISIS. (shrink)

Technology, in order to be human, needs to be informed by a reflection on what it is to be a tool in ways appropriate to humans. This involves both an instrumental, appropriating aspect (‘I use this tool’) and a limiting, appropriated one (‘The tool uses me’).

1. T. - Die metaphysischen Urgesetze der Melodik.

Studies have reported high rates of childhood maltreatment among individuals with drug addiction problems; however, investigation about the potentially protective factors to mitigate the effects of maltreatment experiences on motivation to engage in addiction treatment has received less attention. This study aims at exploring the mediating effects of forgiveness and self-efficacy on the association between childhood maltreatment and treatment motivation among drug addicts. A total of 360 male drug addicts were recruited from three mandatory inpatient rehabilitation centers in Malaysia. Participants (...) completed a package of self-report questionnaires including measures of childhood maltreatment experiences, forgiveness, self-efficacy, and motivation for treatment. The analysis conducted using the structural equation model revealed that childhood maltreatment significantly predicted lower treatment motivation, while forgiveness and self-efficacy played a fully mediating role regarding the effect of childhood maltreatment on treatment motivation. In conclusion, these findings suggest that combining the element of forgiveness and self-efficacy in treatment programs appears to benefit the drug addicts with childhood maltreatment history. (shrink)

The paper is a critical discussion of scholarship on the "Critique of Pure Reason" published during the past ten years. The emphasis is on Anglo-American authors. I identify and discuss three main trends in the field: a shift from the general discussion of transcendental arguments to the analysis and evaluation of particular proofs in Kant; a renewed interest in the doctrine of transcendental idealism and the distinction between things in themselves and appearances; and the emergence of an entire body of (...) literature on Kant's philosophy of mind, centered around the idea of a "transcendental psychology." The main body of the text is supplemented by extensive bibliographical information provided in the notes. (shrink)

As Husserl already noticed, artworks themselves have a phenomenological character. This means, however, that to experience artworks as phenomena no “epoché” and no “phenomenological reduction” is necessary. The leading question of my essay is whether, and possibly how, this observation can be methodologically generalized for understanding phenomena. I discuss if, and possibly how, a phenomenological reflection on art allows and even demands a general conception of phenomenology that nevertheless does not confuse artworks with phenomena in general. My intention is to (...) show that and how phenomenality can be clarified with reference to its spatial character. Accordingly, works of architecture that are artworks will play a decisive role in my argument. (shrink)

In part because “imagination” is a slippery notion, its exact role in the production of scientific knowledge remains unclear. There is, however, one often explicit and deliberate use of imagination by scientists that can be (and has been) studied intensively by epistemologists and historians of science: thought experiments. The main goal of this article is to document the varieties of thought experimentation, not so much in terms of the different sciences in which they occur but rather in terms of the (...) different functions they fulfil. I argue that thought experimentation (and hence imagination) plays a role not only in theory choice but in singular causal analysis and scientific discovery as well. I pinpoint, moreover, some of the rules governing the use of thought experiments in theory choice and in singular causal analysis, that is, some of the criteria they should meet in order to fulfil those functions successfully. (shrink)

Scientific exploration and thus our knowledge about the outside world is subject to the conditions of our experience.These conditions are condensed here into an interface model which,besides being physical,has an additional interface structure not reducible to physics. We suggest that this structure can dynamically be characterized by separate modes.Their selection and operation presupposes free will and a rudimentary concept of time and space. Based on some analogies with quantum networks it is argued that the 'observed' gets 'dressed'as a consequence of (...) the observing. Interface dynamics and system dynamics supplement each other without over- determination. (shrink)

This article compares Kant and Fichte from the double stand- point of identity and difference with regard to two thinkers who were at first united by a master-student relation but who later on drifted apart from each other due to mutual defamation. At the center of the present discussion stands the relationship between spirit of freedom and system’s form which binds Kant and Fichte beyond methodological divergences and doctrinal differ- ences. The critical comparison between Kant and Fichte will be developed (...) in four steps: it will start with the general positioning of Kant within German Idealism, and then move on to Kant’s double critical enterprise of grounding an aprioristic doctrine of principles of nature and freedom; it will later on address the conception championed by Fichte of having pre- sented the “first system of freedom”, and from there it will focus on the manifestations of freedom within Fichte’s philosophical system, with Kant’s position as contrast. (shrink)

In part because "imagination" is a slippery notion, its exact role in the production of scientific knowledge remains unclear. There is, however, one often explicit and deliberate use of imagination by scientists that can be (and has been) studied intensively by epistemologists and historians of science: thought experiments. The main goal of this article is to document the varieties of thought experimentation, not so much in terms of the different sciences in which they occur but rather in terms of the (...) different functions they fulfil. I argue that thought experimentation (and hence imagination) plays a role not only in theory choice but in singular causal analysis and scientific discovery as well. I pinpoint, moreover, some of the rules governing the use of thought experiments in theory choice and in singular causal analysis, that is, some of the criteria they should meet in order to fulfil those functions successfully. (shrink)

Although interest in them is clearly growing, most professional historians do not accept thought experiments as appropriate tools. Advocates of the deliberate use of thought experiments in history argue that without counterfactuals, causal attributions in history do not make sense. Whereas such arguments play upon the meaning of causation in history, this article focuses on the reasoning processes by which historians arrive at causal explanations. First, we discuss the roles thought experiments play in arriving at explanations of both facts and (...) contrasts. Then, we pinpoint the functions thought experiments fulfill in arriving at weighted explanations of contrasts. (shrink)

When people speak about “communication barriers”, what they usually think about are such things as the limitations set by human nature itself, or the constraints that are inherent in the tools we use for communicating. As an example of the first, consider the limited range of the naked human voice; for the second, we may think of the limitations imposed by such primitive communicative devices as the bonfire, the heliograph, or an old-fashioned megaphone.Our contribution draws attention to the fact that, (...) despite enormous advances on the technological side of human communication (such as demonstrated by the existence and use of computers as communication devices), there still are some barriers to be removed as far as the human side is concerned. We call these barriers the “stumble-blocks of the mind”. Their existence is demonstrated by the study of two case stories, which show that understanding the communicative implications of computerizing information is more important than increased emphasis on ever fancier and more expensive hardware products.The next question has to do with the reasons for these “stumbling blocks” to occur. Current communicative and linguistic theoretical findings are used in an effort to explain and solve the communicative dilemmas that are encountered in the organization of our communication, among others in the area of human-computer interface. In particular, the notion of “privacy” in speech acting is suggested as an overlooked aspect, and the notion of “information transfer” is replaced by that of “creating mental activity”.Finally, some conclusions are drawn, and a number of practical applications are offered. (shrink)

This volume is part of the series ‘Pragmatics, Philosophy and Psychology’, edited for Springer by Alessandro Capone. It is intended for an audience of undergraduate and graduate students, as well as postgraduate and advanced researchers. This volume focuses on societal pragmatics. One of the main concerns of societal pragmatics is the world of language users. We are interested in the investigation of linguistic practices in the context of societal practices. It is clear that the world of users, including their practices, (...) their culture, and their social aims has to be taken into account and seriously investigated when we deal with the pragmatics of language. It is not enough to discuss principles of language use solely in the guise of abstract theoretical tools. Consequently, the present volume focuses explicitly on the interplay of abstract, theoretical principles and the necessities imposed by societal contexts often requiring a more flexible use of such theoretical tools. The volume includes articles on pragmemes, politeness and anti-politeness, dialogue, joint utterances, discourse markers, pragmatics and the law, institutional discourse, critical discourse analysis, pragmatics and culture, cultural scripts, argumentation theory, connectives and argumentation, language games and psychotherapy, slurs, the analysis of funerary rites, as well as an authoritative chapter by Jacob L. Mey on societal pragmatics. (shrink)

In some of the papers in which she develops and defends the mental modelview of thought experiments in physics, Nersessian expresses the belief that her account has implications for thought experiments in other domains as well. In this paper, I argue, firstly, that counterfactual reasoning has a legitimate place in historical inquiry, and secondly, that the mental model view can account for such "alternative histories". I proceed as follows. Firstly, I review the main accounts of thought experiments in physics and (...) point at some explanatory advantages of the mental model view. Subsequently, I argue that historians cannot dispense with counterfactual reasoning altogether and qualify a number of principled objections against the explicit use of alternative histories for theoretical purposes. Finally, I show that the mental model view can account for such thought experiments in history. (shrink)

Although the importance, both historically and systematically, of the seventeenth century distinction between primary and secondary qualities is commonly recognised, there is no consensus on its exact nature. Apparently, one of the main difficulties in its interpretation is to tell the constitutive from the argumentative elements. In this paper, we focus on the primary-secondary quality distinctions drawn by Boyle and Locke. We criticise, more specifically, MacIntosh’s analysis of them. On the one hand, MacIntosh attributes too many different primary-secondary quality distinctions (...) to Boyle and Locke. On the other hand, he forbears to attribute a particular primary-secondary quality distinction to them, which, at least in the case of Boyle, differs genuinely from his main distinction between the mechanical affections of matter and all of matter’s other qualities. (shrink)

Some scholars suspect that thought experiments have something in common with jokes. Moreover, Thomas Kuhn has suggested that what happens to someone who thinks through a thought experiment “is very similar to what happens to a man, like Lavoisier, who must assimilate the result of a new unexpected experimental discovery” (1964: 321). In this paper, I pinpoint the presumed commonalities. I identify, more specifically, what cognitive linguists call “incongruity-resolution” as the problem-solving process not only involved in humor comprehension, but in (...) scientific discovery and thought experimentation as well. (shrink)

Historische en systematische artikelen van Nederlandstalige filosofen over diverse aspecten van scepticisme, toen en nu, in filosofie, religie en wetenschap.

For almost fifty years, David Armstrong has made major contributions in analytic philosophy. The aim of this volume is to collect papers that situate, discuss and critically assess Armstrong’s contributions. The book is organized in three parts. In Section I: Analytical Metaphysics and Its Methodology, certain basic principles of analytic metaphysics advocated by Armstrong (such as truthmaker maximalism and the Doctrine of Ontological Free Lunch) and their consequences are critically examined. The articles of Section II: Laws of Nature, Dispositions, and (...) Modality, study the constraints Armstrong’s naturalism sets to his ontology of modality, laws and dispositions. Finally, the articles of Section III: Mind and Epistemology, study and critically evaluate Armstrong’s contributions in epistemology, the philosophy of perception and color. The collection is meant for all philosophers and scholars interested in these central topics of analytic philosophy. (shrink)

Although Thomas More is an exemplary figure of both personal and moral integrity, his Utopia is not straightforwardly ‘integer’ in another meaning of the term, i.e., it does not unequivocally describe a ‘whole, intact or pure’ conception of the ideal society. Rather, Utopia is patently ambiguous and challenges the reader to disambiguate the narrative and to make up his own mind on how to construct the ideal society. In this paper, I analyze utopias and dystopias in general as evaluative thought (...) experiments that appeal to our imagination and deploy possible worlds. Subsequently, I argue that More’s Utopia is a successful evaluative thought experiment that actually underscores More’s integrity, because by means of its exacerbated ambiguity, it both triggers and properly respects the deliberation and evaluation of the reader in his capacity as thought experimenter. (shrink)

In some of the papers in which she develops and defends the mental modelview of thought experiments in physics, Nersessian expresses the belief that her account has implications for thought experiments in other domains as well. In this paper, I argue, firstly, that counterfactual reasoning has a legitimate place in historical inquiry, and secondly, that the mental model view can account for such "alternative histories". I proceed as follows. Firstly, I review the main accounts of thought experiments in physics and (...) point at some explanatory advantages of the mental model view. Subsequently, I argue that historians cannot dispense with counterfactual reasoning altogether and qualify a number of principled objections against the explicit use of alternative histories for theoretical purposes. Finally, I show that the mental model view can account for such thought experiments in history. (shrink)

El presente artículo compara a Kant y a Fichte en la perspectiva doble de identidad y diferencia referida a dos pensadores a quienes une una primera relación de maestro y alumno y a quienes separa una posterior difamación mutua. En el centro de la presentación se encuentra la relación entre espíritu de libertad y forma del sistema que une a Kant y a Fichte más allá de divergencias metódicas y de diferencias doctrinales. La comparación crítica entre Kant y Fichte se (...) desarrollará en cuatro etapas: partirá de la ubicación general de Kant dentro del idealismo alemán y se extenderá a la empresa doble de Kant, expresada de forma crítica, de una doctrina de los principios apriorística de naturaleza y libertad, para después ir a la concepción enfáticamente reclamada por Fichte de un “primer sistema de la libertad”,[1] y de ahí a las manifestaciones de la libertad en el sistema filosófico de Fichte, teniendo como punto de vista rector el contraste con Kant.[2] Palabras clave: [1] En la forma de citación de la Gesamtausgabe de Fichte se señalará el tomo y el volumen con números romanos y arábigos respectivamente, y después el número de página en cuestión. [2] El presente artículo es parte de un proyecto de carácter más amplio, cuyo tema es la dilucidación del aporte filosófico de Kant y de Fichte; de ahí que se haga continua referencia a publicaciones particulares de mi autoría. (shrink)