The pandemic reminds us that, with the catastrophes to which biodiversity is subjected, with the disruption of ecosystems, much more dangerous and fatal viruses can appear. Also, disturbed in its quietude and reminded of its own mortality, the human being knows the same anguishes which were those of all the victims of the epidemics which formerly devastated the populations and of which the literature was able to account in multiple occasions. Daniel Defoe’s Diary of the Plague, which is very rich (...) in lessons, bears witness to the similarities in attitude between the centuries: disruption of the economy, unemployment, famine, rumors, the search for false remedies, confinement, transgressions. Conjuring up confinement through writing is a remedy that tempts some. With the sound diary of the writer Wajdi Mouawad it is from the inside that the experience of confinement is given to understand. (shrink)

La dénomination des âges, résultat d’un construit social, trace des frontières mobiles qui sont autant de marqueurs socioculturels. La frontière a un double statut : objectif et subjectif, externe et interne, elle est continuellement édifiée et reconstruite selon le contexte socio-historique et culturel et les interactions. C’est un mur ou un lieu de passage. Une série d’entretiens auprès de jeunes chômeurs en formation et auprès de personnes âgées confrontées aux bouleversements urbains montre que l’âge peut être vécu soit comme processus (...) dynamique de transformation dans son rapport à soi, aux autres et à son environnement, soit comme processus d’exclusion et de mort sociale.The ways in which we refer to ages in life, which stem from social constructs, point to shifting boundaries that are effectively socio-cultural demarcations. The nature of boundaries is inherently dual: they are objective and subjective, external and internal, and they are continually erected and reconstructed with shifting socio-historical and cultural contexts and interactions. They are barriers but also gateways. A series of interviews with young unemployed people in training and with elderly people trying to cope with urban transformations shows that one’s age can either be experienced as a dynamic process of change in one’s relationships with oneself, with others and with one’s environment, or as a process of exclusion and social death. (shrink)

Distinguer le rituel de la ritualisation, c'est opposer l'aspect statique du rituel, comme disposition collective mobilisée par un groupe ou une communauté pour gérer ses interactions entre ses membres et son contact avec d'autres groupes, d'avec l'aspect dynamique des processus d'instauration de règles de fonctionnement de nouvelles formes d'agir social. La ritualisation des processus d'apprentissage et de formation réclame l'instauration inaugurale d'un cadre. Celui-ci renvoie à l'explicitation volontaire, réitérée des règles de fonctionnement, par un animateur symboliquement garant de la loi. (...) En ce sens cette distinction postule, à côté d'une approche fonctionnelle du rite, une approche génétique des processus de ritualisation. Par ritualisation, j'entends la mise en place progressive d'habitus au moyen d'un cadre, édictant les règles de fonctionnement et les objectifs de l'activité. Au paradigme d'une causalité circulaire, qui présente les rituels à la fois comme résultats et comme producteurs d'habitus, on peut opposer le modèle d'une causalité linéaire qui pose le cadre comme induisant des processus d'apprentissage ritualisés. L'étude se focalise plus spécialement sur les rituels d'accueil et sur le démarrage des processus d'apprentissage et de formation ritualisés.Distinguish the ritual of ritual is to oppose the static aspect of the ritual, as collective provision mobilized by a group or a community to manage interactions between its members and contact with other groups, with the appearance dynamic process of establishing operating rules for new forms of social action. The ritualization of learning and training calls for the establishment of a framework inaugural. It refers to explaining voluntary repeated operating rules by a facilitator symbolic guarantor of the law. In this sense the distinction postulates next to a functional approach to the rite, a genetic process of ritualization. By ritual, I mean the gradual establishment of habitus through a frame, establishing the rules of operation and objectives of the activity. Paradigm of circular causality, which presents the rituals both as producers and as a result of habit, we can contrast the model of linear causality that arises as part of the learning process inducing ritualized. The study focuses especially on the rituals of home and starting the process of learning and training ritualized. (shrink)

The recently uncovered role of Fukutin‐related protein (FKRP) in fibronectin glycosylation has challenged our understanding of the basis of disease pathogenesis in the muscular dystrophies. FKRP is a Golgi‐resident glycosyltransferase implicated in a broad spectrum of muscular dystrophy (MD) pathologies that are not fully attributable to the well‐described α‐Dystroglycan hypoglycosylation. By revealing a new role for FKRP in the glycosylation of fibronectin, a modification critical for the development of the muscle basement membrane (MBM) and its associated muscle linkages, new possibilities (...) for understanding clinical phenotype arise. This modification involves an interaction between FKRP and myosin‐10, a protein involved in the Golgi organization and function. These observations suggest a FKRP nexus exists that controls two critical aspects to muscle fibre integrity, both fibre stability at the MBM and its elastic properties. This review explores the new potential disease axis in the context of our current knowledge of muscular dystrophies. (shrink)

Previous studies using the dot-perspective task postulated that people automatically take into account others' perspective even when it prevents them from achieving their own goals. This human ability may be of key importance for the ascription of mental states and social interactions. The cognitive and emotional determinants of automatic perspective taking is still matter of debate. To address this issue, we examined the performance in the Samson et al. APT task in 91 healthy adults who underwent a detailed neuropsychological testing (...) including assessment of their general intelligence, attention and impulsivity, alexithymia, and measures of affective empathy and explicit theory of mind. Univariate and multiple linear regression models were used to explore the association between mean reaction times in the APT task, and the CPT-II parameters, WAIS global score, TAS, and GeSoCS and mini-SEA scores. Only the CPT-II parameters were significantly associated with the mean reaction times. Increased omissions, commissions, and detectability as well as hit reaction time standard error in CPT-II were all related to worse performances both in Self and Other conditions. The mean number of errors was negatively associated with the GeSoCS score. Among the variables studied, only CPT-II parameters had a significant impact on egocentric and altercentric interference. Neither global intelligence nor alexithymia have an effect on dot-perspective task performance. The present findings suggest that people with lower attentional resources and increased impulsivity display worse performances in the APT task and are less responsive to both egocentric and altercentric interference. (shrink)

An examination of verbal hallucinations and thought insertion as examples of "alienated self-consciousness.".

Hume's Reception in Early America: Expanded Edition brings together the original American responses to one of Britain's greatest men of letters, David Hume. Now available as a single volume paperback, this new edition includes updated further readings suggestions and dozens of additional primary sources gathered together in a completely new concluding section. From complete pamphlets and booklets, to poems, reviews, and letters, to extracts from newspapers, religious magazines and literary and political journals, this book's contents come from a wide variety (...) of sources published in colonial America and the early United States between 1758 and 1850. As well as classics by Thomas Jefferson, John Adams and Alexander Hamilton, it contains scores of unknown and hard-to-locate items, many of which have not been reprinted since their original publication. These responses are divided into four parts covering Hume's Essays; his Philosophical Writings; his History of England; and his Character and Death. Each of those parts has a separate introductory essay, and every selection is introduced by a short headnote that sets the piece in its historical context and provides bibliographical references. Packed with new insights into Hume and American thought and culture, Hume's Reception in Early America reveals the relevance and impact of Hume on American political, philosophical, historical, religious, and aesthetic debates. (shrink)

This entirely new work guides the reader through the most basic systems of modal propositional logic up to systems of modal predicate with identity, dealing with both technical developments and discussing philosophical applications.

Biological evolution is a complex blend of ever changing structural stability, variability and emergence of new phe- notypes, niches, ecosystems. We wish to argue that the evo- lution of life marks the end of a physics world view of law entailed dynamics. Our considerations depend upon dis- cussing the variability of the very ”contexts of life”: the in- teractions between organisms, biological niches and ecosys- tems. These are ever changing, intrinsically indeterminate and even unprestatable: we do not know ahead of (...) time the ”niches” which constitute the boundary conditions on selec- tion. More generally, by the mathematical unprestatability of the ”phase space”, no laws of mo- tion can be formulated for evolution. We call this radical emergence, from life to life. The purpose of this paper is the integration of variation and diversity in a sound concep- tual frame and situate unpredictability at a novel theoretical level, that of the very phase space. Our argument will be carried on in close comparisons with physics and the mathematical constructions of phase spaces in that discipline. The role of symmetries as invariant preserving transformations will allow us to under- stand the nature of physical phase spaces and to stress the differences required for a sound biological theoretizing. In this frame, we discuss the novel notion of ”enablement”. Life lives in a web of enablement and radical emergence. This will restrict causal analyses to differential cases. Mutations or other causal differ- ences will allow us to stress that ”non conservation princi- ples” are at the core of evolution, in contrast to physical dynamics, largely based on conservation principles as sym- metries. Critical transitions, the main locus of symmetry changes in physics, will be discussed, and lead to ”extended criticality” as a conceptual frame for a better understanding of the living state of matter. (shrink)

Editor James Fetzer presents an analytical and historical introduction and a comprehensive bibliography together with selections of many of Carl G. Hempel's most important studies to give students and scholars an ideal opportunity to appreciate the enduring contributions of one of the most influential philosophers of science of the 20th century.

One of Hume's most well-known works and a masterpiece of philosophy, A Treatise of Human Nature is indubitably worth taking the time to read.

Lycan not only uses the numerous arguments against materialism, and functionalist theories of mind in particular, to gain a more detailed positive view of the ..

This is a welcome reprint of a book that continues to grow in importance.

Throughout his career, Schelling assigns knowledge of the absolute first principle of philosophy to intellectual intuition. Schelling's doctrine of intellectual intuition raises two important questions for interpreters. First, given that his doctrine undergoes several changes before and after his identity philosophy, to what extent can he be said to “hold onto” the same “sense” of it by the 1830s, as he claims? Second, given that his doctrine of intellectual intuition restricts absolute idealism to what he calls a “science of reason”, (...) which he says cannot prove the absolute’s existence, what other doctrine does he require in order to prove this? I will answer these questions by tracing the shifts in Schelling’s doctrine of intellectual intuition from the 1790s to the 1830s and drawing out its evolving methodological role within his science of intelligibility. (shrink)

A model for the ideal state includes discussions of the nature and application of justice, the role of the philosopher in society, the goals of education, and the effects of art upon character.

Includes bibliographical references and index.

The COVID-19 pandemic revealed numerous weaknesses in pandemic preparedness and response, including underfunding, inadequate surveillance, and inequitable distribution of countermeasures. To overcome these weaknesses for future pandemics, WHO released a zero draft of a pandemic treaty in February, 2023, and subsequently a revised bureau's text in May, 2023. COVID-19 made clear that pandemic prevention, preparedness, and response reflect choices and value judgements. These decisions are therefore not a purely scientific or technical exercise, but are fundamentally grounded in ethics. The latest (...) treaty draft reflects these ethical considerations by including a section entitled Guiding Principles and Approaches. Most of these principles are ethical—they establish core values that undergird the treaty. Unfortunately, the treaty draft's set of principles are numerous, overlapping, and show inadequate coherence and consistency. We propose two improvements to this section of the draft pandemic treaty. First, key guiding ethical principles should be clearer and more precise than they currently are. Second, the link between ethical principles and policy implementation should be clearly established and define boundaries on acceptable interpretation, ensuring that signatories abide by these principles. (shrink)

This paper aims to show that Godel's ontological argument can be parodied in much the same kind of way in which Gaunilo parodied Anselm's Proslogion argument. The parody in this paper fails; there is a patch provided in "Reply to Gettings" (Analysis 60, 4, 2000, 363-7).

R.I.G Hughes offers the first detailed and accessible analysis of the Hilbert-space models used in quantum theory and explains why they are so successful.