Many states prohibit patients from appointing their physicians as health care proxies, fearing paternalism and conflict of interest. But the potential for conflict is not unique to physicians, and patients may have compelling reasons to prefer that their doctor make decisions on their behalf. Managing potential conflicts serves patients better than denying them the right to choose who will make health care decisions for them when they are no longer competent.

Through an ethnographic study of online saree pacts and social media groups, this article charts the emergence of digital saree storytelling as women from India and the global South Asian diaspora post stories about their personal and professional lives while also talking about their sarees. The article examines how saree stories are told and consumed in these online spaces, and the role new media plays in encouraging individual and collective self-expression through fashion. In doing so, it highlights how saree pacts (...) allow for alternative models of fashion opinion leadership and style to emerge in ways that are uplifting and empowering for women who are otherwise underrepresented in print and popular fashion media. It argues that such sites are critical spaces shifting the narrative around women in the Global South from victimhood to pleasure. Additionally, saree pacts represent a new form of digital community formation centred around the appreciation of traditional fashion, which can alter our perception of the intersection of traditional fashion and feminism while also decolonising fashion's existing Eurocentric frameworks. (shrink)

With the human genome mapped, and with the mapping of more than one hundred animal genomes in progress, the amount of genetic data available is increasing exponentially. This exponential increase in data is having an immediate impact on the process of drug development. By using techniques of information technology to manipulate data regarding the genes, proteins, and biochemical pathways associated with various diseases, scientists are beginning to be able to design drugs in a systematic fashion. In the context of any (...) given disease, scientists look to see whether a gene, a protein for which the gene codes, or another protein in the relevant biochemical pathway could be the “target” biological molecule, the “knocking out” of which would halt or slow the disease's progression. Once a target molecule has been identified and characterized structurally, drug therapies that would be likely to knock out this target can be identified and tested systematically. The merger of information technology and genetic technology has changed the process of pharmaceutical development so much that a new term—bioinformatics—has been coined to describe this new approach to such development. (shrink)

J. S. Russell has argued that it is morally permissible for children to participate in dangerous sports and that much of value can be gained from such participation. He attempts to justify children’s participation in dangerous sport with two arguments, which he calls the common sense view and the uncommon sense view, and I apply the basic reasons given in these general arguments to the specific case of justifying children’s participation in mixed martial arts (MMA). To safeguard against wanton and (...) gratuitous risk of great harm, Russell also includes some basic limitations for children’s participation in dangerous sports, and I use these limitations as a general framework for providing a number of additional constraints to render children’s MMA morally permissible. (shrink)

This paper is divided into six parts. The first presents a rudimentary definition of ethics based on Western philosophical theories, particularly their concern for articulating universal moral principles. The second examines the assumptions anchoring Western moral philosophies, and raises the question: are the philosophical presuppositions of modern Western philosophy consistent with the presuppositions of Hinduism? It concludes that the two are not entirely in agreement, particularly on the issue of personal and social identity. The third section locates areas in Hinduism (...) that discursively concur with the concerns of Western ethicists, and explores the limits of the semblance. The fourth identifies problematic areas, and raises the question: should the idea of universal ethics be abandoned for Hinduism? The fifth section concludes that such abandonment would be hasty, and initiates a searching look into the Hindu epics for concepts that, while not identical with may still be parallel to some Western notions of ethics. The sixth looks at the content of normative Hindu morality, and generalizes on the basis of this content about the nature of "Hindu ethics". (shrink)

From his earliest publications until his last, Francis Bacon displayed an intense interest in theo- logical and religious issues, and expressed this interest in both public and private. On the other hand, he has long been recognized for his proposals for a grand reform and reconstruction of natural philosophy, in which experience, observation, experiment, and technological implementation of abstract claims all took center stage. This practical bent has often neatly been encapsu- lated in the slogan derived from Bacon himself, ‘knowledge (...) is power.’ The many and interesting connections between these two sets of interests – the theological and the natural philosophical – have not gone unnoticed by scholars; however, one central component of Bacon’s pragmatic approach to natural philosophy that was deeply influenced by his theological concerns has remained unexplored. The equation between knowledge and power, so well known, in fact developed out of Bacon’s conception of the Christian Trinity, and out of the rela- tionship between the Trinity and humanity’s pursuit of knowledge about nature. It is the task of this essay to trace the development of this connection from the beginnings of Bacon’s literary career until its end. (shrink)

Many video games require complex, rapid sequences of skilled bodily movements in order to complete game-world tasks. It is not unreasonable to think that this might interfere with our ability to aesthetically appreciate such video games. I present two versions of this argument from extreme difficulty: a strong version and a weak version. While extant treatments of the aesthetics of video games can be used to rebut the strong version, the weak version remains recalcitrant. I develop a reply to the (...) weak version, use it to clarify key features of reasons used by video-game critics to argue in favor of their critical judgments, and to illuminate the development of video games over time. (shrink)

Comment la bande dessinée rend-elle compte de l’argent ? Comment sont pensés les liens entre argent et lien social ? Ce texte essaie de répondre à ces questions en examinant principalement trois récits grand public dans lesquels utopie de l’absence de monnaie et contre-utopie de l’introduction de la monnaie sont âprement discutées : Obélix et Compagnie , Le Schtroumpf financier et Achille Talon et l’Archipel de Sanzunron . Si les deux premiers décrivent un univers perturbé par l’introduction de la monnaie (...) et les valeurs nouvelles qu’elle véhicule, le troisième dénonce comme utopique l’idée de s’extraire des rapports d’argent. La représentation commune de l’argent que véhicule la bande dessinée apparaît généralement fortement négative.How do comics handle the idea of money? How do they reflect on the relationships between money and social ties? This paper attempts to answer these questions, mainly through an examination of three stories aimed at a general readership and involving a fierce contest between a Utopian absence of money and a aimed at a general readership and involving a fierce contest between a Utopian absence of money and a counter-Utopian advent of money: “Obélix et Compagnie” , “Le Schtroumpf financier” and “Achille Talon et l’Archipel de Sanzunron” . While the first two describe a world disrupted by the introduction of money and the new values it conveys, the third denounces the idea of withdrawing from monetary relationships as Utopian. In general, representations of money conveyed by comics are highly negative. (shrink)

Rassemble des études autour de la notion de parrhêsia, de dire-vrai ou de franc-parler dans la culture grecque, qui constitue un élément fondamental de la pensée de Foucault.

Drawing on a landscape analysis of existing data-sharing initiatives, in-depth interviews with expert stakeholders, and public deliberations with community advisory panels across the U.S., we describe features of the evolving medical information commons. We identify participant-centricity and trustworthiness as the most important features of an MIC and discuss the implications for those seeking to create a sustainable, useful, and widely available collection of linked resources for research and other purposes.

Business Ethics, the Environment &Responsibility, Volume 32, Issue 4, Page 1452-1469, October 2023.

It appears that both English and French contain a mixture of ergative and transitive verbal constructions. How useful is reference to a dual-structure model of syntax in determining the bias of a particular language? Certain verbal constructions in English and French could be generated from either transitive or ergative deep structures; we must therefore turn to other criteria - syntactic cohesion and predominant constituent structures in 'surface structure' - for a non-arbitrary - and adequate - decision.

I wish to present a codi cation of syntactic approaches to dealing with ergative languages and argue for the correctness of one particular approach, which I will call the Inverse Grammatical Relations hypothesis.1 I presume familiarity with the term `ergativity', but, brie y, many languages have ergative case marking, such as Burushaski in (1), in contrast to the accusative case marking of Latin in (2). More generally, if we follow Dixon (1979) and use A to mark the agent-like argument of (...) a transitive verb, O to mark the patient-like argument of a transitive verb, and S to mark the single argument of an intransitive verb, then we can call ergative any subsystem of a language that groups S and O in contrast to A, as shown in (3). (shrink)

Mike Anderson1 has given us a thoughtful and useful field guide: Not in the genre of a bird-watcher’s guide which is carried in the field and which contains detailed descriptions of possible sightings, but in the sense of a guide to a field (in this case embodied cognition) which aims to identify that field’s general principles and properties. I’d like to make some comments that will hopefully complement Anderson’s work, highlighting points of agreement and disagreement between his view of the (...) field and my own, and acting as a devil’s advocate in places where further discussion seems to be required. Given the venue for this guide, we can safely restrict the discussion to embodied artificial intelligence (EAI), even if such work draws on notions of embodied cognition.. (shrink)

Arti cial life studies computer models of the processes characteristic of complex adaptive systems|processes like self-organization, self-reproduction, adaptation, and evolution. Complex adaptive systems take many forms, each of which di ers from the others in myriad ways. By abstracting away from the diverse details, arti cial life hopes to reveal fundamental principles governing broad classes of complex adaptive systems. This hope rests on arti cial life's working hypoth-.

Ergative languages make up a substantial percentage of the world’s languages. They have a case system which distinguishes the subject of a transitive verb from that of an intransitive, grouping the latter with the object — that is, the object of a transitive verb and the subject of an intransitive verb are in the same case, which we refer to as the nominative. However, ergative languages differ from one another in important ways. In Greenlandic Eskimo the nominative, whether it is (...) a subject or an object, is syntactically prominent in the clause, much like a subject in English; but in Warlpiri, the nominative is not prominent, more like an object. The variable prominence of the nominative manifests itself as well in the semantics, e.g., default scope of indefinite and quantified nominals. Using data from Greenlandic Eskimo and Warlpiri, and from Hindi, which represents a split ergative system, this paper develops a general theory of case which explains the observed differences amongst ergative languages. In addition, the theory is designed to account for the accusative language type, represented by English. (shrink)

Attempts to give necessary and sufficient conditions for demarcating ‘dispositional’ predicates (such as ‘is fragile’) from other predicates are generally acknowledged to fail. This leaves unresolved the question of what it is about paradigm instances of dispositional predicates in virtue of which their application to an object constitutes a disposition ascription. This essay proposes that dispositional predicates are generally derived from ergative verbs, those verbs that allow for certain entailments from transitive to intransitive forms (as ‘Sam broke the glass’ entails (...) ‘The glass broke’). The connection between disposition ascriptions and ergativity is shown to have consequences for the metaphysics of dispositions. (shrink)

La lex artis es el criterio que emplea el Derecho para determinar la corrección de la práctica médica y, por analogía, de otras profesiones o actividades. Se trata, por tanto, de un factor decisivo para concretar el alcance de los deberes, responsabilidades y derechos de los profesionales y los usuarios.

What makes a cell? How are cells able to replicate themselves in a stable manner? How did cellular life emerge on our planet? The answer to these fundamental questions lies at the base of biology. Cellular life is the basic unit of living organization and defines the presence of a stable information reservoir connected through the external world by a well-defined boundary. Inside the cell, chains of computations and chemical reactions take place, sustained by self-assembled molecular machines. At the cell (...) membrane, the environment and the cell communicate with each other through proteins that are able to detect small concentration changes and send the appropriate signals. But modern cells are very sophisticated entities and extracting the logic of cell organization from them is a gigantic effort. In order to answer these questions, we need to look at cells in a more basic level: a reduction of complexity is needed. Protocells, roughly defined as the simplest instances of autonomous cell-like structures, have been a matter of exploration for decades. Although most of the original work in this area was largely theoretical, the end of the twentieth century was marked by very active experimental research on minimal cells. One approach has been the top-down strategy, where living organisms (the simplest life forms) are being selectively modified to reduce their genome complexity. Such a minimal genome would be the smallest one able to sustain reproduction and growth under a given set of external constraints (mainly available molecules). The second approach is the bottom-up one, very much in the tradition of research into the origins of life. Under this approach, extremely simple life forms are built from basic chemical components, including lipids and a basic.. (shrink)