The “fair benefits” approach to international research is designed to produce results that all can agree are fair without taking a stand on divisive questions of justice. But its appealing veneer of collaboration masks ambiguities at both a conceptual and an operational level. An attempt to put it into practice would look a lot like an auction, leaving little reason to think the outcomes will satisfy even minimal conditions of fairness.

This article argues that lingering uncertainty about the normative foundations of research ethics is perpetuated by two unfounded dogmas of research ethics. The first dogma is that clinical research, as a social activity, is an inherently utilitarian endeavor. The second dogma is that an acceptable framework for research ethics must impose constraints on this endeavor whose moral force is grounded in role-related obligations of either physicians or researchers. This article argues that these dogmas are common to traditional articulations of the (...) equipoise requirement and to recently articulated alternatives, such as the non-exploitation approach. Moreover, important shortcomings of these approaches can be traced to their acceptance of these dogmas. After highlighting these shortcomings, this article illustrates the benefits of rejecting these dogmas by sketching the broad outlines of an alternative called the "integrative approach" to clinical research. (shrink)

Before participants can be enrolled in a clinical trial, an institutional review board must determine that the risks that the research poses to participants are ‘reasonable.’ This paper examines the two dominant frameworks for assessing research risks and argues that each approach suffers from significant shortcomings. It then considers what issues must be addressed in order to construct a framework for risk assessment that is grounded in a compelling normative foundation and might provide more operationally precise guidance to the deliberations (...) of various stakeholders. The paper concludes by sketching the outlines of what is referred to as the ‘Integrative Approach’ to risk assessment and by highlighting some of the ways in which this approach may be more promising than current alternatives. (shrink)

In the preface, Kim writes hopefully that his introduction to the philosophy of mind is “intended to be accessible to those without a formal background in philosophy”. The blurb at the end is more realistic: Philosophy of Mind is “a textbook for upper-level undergraduates and graduate students”. It is an admirable addition to Westview’s excellent Dimensions of Philosophy series. Brisk, workmanlike chapters profile the usual suspects: behaviorism, the identity theory, mind as computer and as causal structure, mental causation, consciousness, mental (...) content, and reductive and nonreductive physicalism. Each chapter ends with a useful note on further readings. (shrink)

The threat of biological and chemical terrorism highlights a growing tension in research ethics between respecting the interests of individuals and safeguarding and protecting the common good. But what it actually means to protect the common good is rarely scrutinized. There are two conceptions of the common good that provide very different accounts of the limits of permissible medical research. Decisions about the limits of acceptable medical research in defense of the common good should be carried out only within the (...) latter framework. (shrink)

Starting with the French Revolution Massacres and Morality studies mass killing as perpetrated by states. In particular it examines the role that civilian immunity has played in shaping the behaviour of perpetrators and how international society has responded.

A pragmatic approach to business ethics is argued for in this volume, which demonstrates the usefulness of the approach by applying it to a variety of issues. These issues are broad and far-reaching and include the relations between rational and moral//ethical decision-making, the limits of loyalty to employers, the impact of trust on business and the role of commercial public opinion polling during elections. The author also covers advertising, tobacco promotion, manufacture and marketing of armaments, concentration and taxation of wealth, (...) and the North American Free Trade Agreement. (shrink)

Geach's account of the Aristotelian logic of categorical sentences supplemented the views shared by Frege, Russell, Quine and others. I argue that this particular predicate logic approach and Geach's points apply to only one variety of natural language categorical sentences. For example, it takes the universal categorical as a universal conditional “If anything is a man, then it is mortal”. A different natural language form can and should be invoked: “Every man is a mortal.” Employing special restricted quantifiers in a (...) version of predicate logic, we justify a full square of opposition and the rules of quality and quantity that Geach rejected. (shrink)

Cohen begins by defining ‘Color Physicalism’ so that the position is incompatible with Color Relationalism (unlike Byrne and Hilbert 2003, 7, and note 18). Physicalism, in any event, is something of a distraction, since Cohen’s argument from perceptual variation is directed against any view on which minor color misperception is common (Byrne and Hilbert 2004). A typical color primitivist, for example, is equally vulnerable to the argument. Suppose that normal human observers S1 and S2 are viewing a chip C, as (...) in Cohen’s example. C looks unique green to S1, and bluish green to S2. The problem, as Cohen has it, is to explain “what could (metaphysically) make it the case” that S1, say, and not S2, is perceiving C correctly. He purports to find the explanation “extremely hard to imagine”, and so concludes that both S1 and S2 are perceiving C correctly. (That is not the only option, of course: Hardin concludes that neither is perceiving the chip correctly.). (shrink)

Commonly we distinguish the strike of a match, as a cause of the match lighting, from the presence of oxygen, as a mere condition. In this paper I propose an account of this phenomenon, which I call causal selection. I suggest some reasons for taking causal selection seriously, and indicate some shortcomings of the popular contrastive approach. Chief among these is the lack of an account of contrast choice. I propose that contrast choice is often just the counterfactual scenario in (...) which the effect does not occur: I suggest that if c causes e , then if e hadn't occurred, c wouldn't have occurred. I argue that this is a necessary condition on causation which causes meet but mere conditions fail. (shrink)

Why Agamben? -- Key ideas -- Language and the negativity of being -- Infancy and archaeological method -- Potentiality and the task of the coming philosophy -- Politics : bare life and sovereign power -- The homeland of gesture : art and cinema -- The laboratory of literature -- Bearing witness and messianic time -- After Agamben.

The definitions of disease proffered by philosophers and medical actors typically require that a state of ill health be linked to some known bodily dysfunction before it is classified as a disease. I argue that such definitions of disease are not fully implementable in current medical discourse and practice. Adhering to the definitions would require that medical actors keep close track of the current state of knowledge on the causes and mechanisms of particular illnesses. Yet, unaddressed problems in medical terminology (...) can make this difficult to do. I show that unrecognized misuse of “heterogeneous,” “biomarker,” and other important health terms—which I call index terms—can misrepresent the current empirical evidence on illness pathophysiology, such that unvalidated illness constructs become mistaken for diseases. Thus, implementing common definitions of disease would require closing this “loophole” in medical discourse. I offer a simple rule that, if followed, could help do just that. (shrink)

Objectives: The COVID-19 pandemic is having a major impact on the lives of everyone, but in particular on the health and well-being of older people. It has also disrupted the way that individuals access services and interact with one another, and physical distancing and “Stay at Home” orders have seen digital interaction become a necessity. While these restrictions have highlighted the importance of technology in everyday life, little is known about how older adults have responded to this change. Methods: Two (...) surveys, one in 2019 and another in 2020 collected data on a combined total of 1923 older adults aged 65 years and older in Canada. These looked at how older adults think about and use technology, with the 2020 survey additionally questioning how COVID-19 has impacted their use and attitudes towards technology. Results: While older adults feel more isolated in 2020, many feel positive about the benefits of technology and have increased technology use during the pandemic to support their health, wellness, and communication needs. Discussion: The results highlight the potential of technology for supporting older adults in various aspects of healthy aging. While these results point to the opportunities afforded by technology, challenges remain, such as how social and economic factors influence technology uptake. (shrink)

1 In 1954 Karl Popper published an article attempting to show that the identification of the quantitative concept degree of confirmation with the quantitative concept degree of probability is a serious error. The error was presumably committed by J. M. Keynes, H. Reichen bach and R. Carnap. 2 It was Popper's intention then, to expose the error and to introduce an explicatum for the prescientific concept of degree of confirmation. A few months later Y. Bar-Hillel published an article attempting to (...) show that no serious error had been committed (particularly by Carnap) and that the problem introduced by Popper was simply a "verbal one. "3 Popper replied immediately that "Dr. Bar-Hillel forces me [Popper] now to criticize Carnap's theory further," and he [Popper] introduced further objections which, if accepted, destroy Carnap's theory. 4 About eight years after this exchange took place I was in graduate school at the University of Chicago in search of a topic for a doctoral dissertation. An investigation of the issues involved in this exchange seemed to be ideal for me because I had (and still have) a great ad miration for the work of both Carnap and Popper. A thoroughly revised and I hope improved account of that investigation appears in the first five chapters of this book. Put very briefly, what I found were four main points of contention. (shrink)

Emergentists such as Samuel Alexander and C. Lloyd Morgan held that the mental is causally efficacious, supervenes on the physical, but does so mysteriously. We must accept the emergent mind, in Alexander's phrase, with "natural piety". Emergentism emerged late last century and all but disappeared in the twentieth. This dissertation attempts to revive the position. ;To explain psycho-physical supervenience is to provide a proof of the mental facts from the physical facts, such that mental vocabulary only occurs in the proof (...) in the form of a priori bridge principles connecting mental goings on with the physical facts. Offering a proof of the mental facts from the physical facts would be one way to justify supervenience, thus simultaneously vindicating and explaining it. ;Those philosophers who try to "naturalize intentionality" can be seen as seeking such proofs for intentional states. Various theories of this kind are considered: those of Fodor, Millikan, Lewis, and others. It is argued in chapters 2 and 3 that these theories are either false or unknowable. ;The case for eliminativism is examined in chapter 4, where it is argued that eliminativism is, of necessity, not a rational thesis to adopt. ;A view found in the writings of Davidson and Dennett is the topic of chapter 5. This is a kind of third-person Cartesianism: a person's mind is completely revealed by the deliverances of a suitably equipped interpreter. This position would elegantly vindicate supervenience without explaining it, at the price of a kind of anti-realism about the mind. It is argued that the price is not worth paying. ;In the sixth chapter it is argued that if the phenomenal aspects of the mind supervene, they do so mysteriously. An argument is then presented for psycho-physical supervenience. It was argued earlier that if supervenience holds for intentional states, it cannot be adequately explained. Therefore physicalism is true, but the mind-body problem has no solution. (shrink)

This article argues that considerations about the role and predictability of intellectual innovation make the protection of intellectual property morally obligatory even when it greatly reduces short-term welfare. Since the provision of good new ideas is the only productive input not subject to decreasing marginal productivity, welfarist considerations require that no impediment to its maximal provision be erected and the potentially substantial welfare losses imposed by a patent system be mitigated by taxation of other sources of wealth and income. Key (...) Words: patent system • welfarism • decreasing marginal productivity. (shrink)

Political scientists generally consider that the incentive for legislators to switch parties lies in their desire to be re-elected. While some scholars attribute defection to the legislators’ popularity and strong connections with their constituents which enable them to be re-elected without relying on party labels, others assert that legislators switch if they perceive that staying put might threaten their chances of re-election. In this paper, we find that the two assumptions, to some extent, contradict each other. More surprisingly, the two (...) contradictory hypotheses cohabit under the single non-transferable vote system. From an analysis of the switching in the Taiwanese Legislative Yuan, the empirical evidence shows that because of fierce intraparty competition in the multimember districts, not only barely elected but also top-ranked legislators switched party affiliation in order to avoid the loss in votes or even seats to their copartisans and to maximize their chances of re-election. (shrink)

This paper discusses a number of themes and arguments in The Quest for Reality: Stroud's distinction between “philosophical” and “ordinary” questions about reality; the similarity he finds between the view that coloris “unreal” and the view that it is “subjective”; his argument against thesecondary quality theory; his argument against the error theory; and the “disappointing” conclusion of the book.

Within international development [1], public health [2], and clinical medicine [3]–[5], there is increasing interest in determining whether cash payments or other economic incentives can be used to influence the choices and behavior of individuals and groups in order to promote desired health goals. However, a number of complex issues affect the review and approval by research ethics committees of research studying the effectiveness of using financial incentives to promote desired health goals. Current ethical and regulatory frameworks regard the provision (...) of gifts or cash payments to participants in human research as potentially problematic. Specifically, these frameworks imply that such incentives may undermine the autonomy of participant choice, hinder the disclosure of medical information, exacerbate social inequalities, or result in the exploitation or degradation of vulnerable populations [6]–[9]. Typically, these frameworks provide guidance about payment to research participants to reimburse expenses, to compensate for time and effort, to provide insurance coverage, or as an incentive to participate in the research itself. However, the issue of payment as a component of the research intervention is relatively new. RECs thus lack explicit guidance about ethical issues surrounding research that evaluates the use of financial incentives as an intervention to promote health. (shrink)

There are good reasons for being dissatisfied with standard criticisms of the various arguments, all of which are referred to as being “The Ontological Argument”. While refutation by logical analogy is compelling, it merely teaches us that something is amiss. It does not specify the exact nature of the flaw. The first part of this paper examines and rejects several well-known attempts at refuting and clarifying the argument(s). The second part attempts to provide a principled uniform account of what is (...) wrong by treating the arguments as resting on definitions. Then, by bringing to bear Ajdukiewicz’s exhaustive classification of definitions, we arrive at a unified account of the flaw common to such arguments. In effect we have an explication of the dictum that one cannot define into existence. (shrink)

Many philosophers call themselves ‘naturalists’ because they believe theism is incompatible with science. However, many also hold that science is compatible with many other theistic beliefs about morality, free will, the mind, and the meaning of life. Those naturalists who reject these other beliefs need a different label for their view. This article recommends the term ‘scientism’.

The social sciences need to take seriously their status as divisions of biology. As such they need to recognize the central role of Darwinian processes in all the phenomena they seek to explain. An argument for this claim is formulated in terms of a small number of relatively precise premises that focus on the nature of the kinds and taxonomies of all the social sciences. The analytical taxonomies of all the social sciences are shown to require a Darwinian approach to (...) human affairs, though not a nativist or genetically driven theory by any means. Non-genetic Darwinian processes have the fundamental role on all human affairs. I expound a general account of how Darwinian processes operate in human affairs by selecting for strategies and sets of strategies individuals and groups employ. I conclude by showing how a great deal of social science can be organized in accordance with Tinbergen’s approach to biological inquiry, an approach required by the fact that the social sciences are all divisions of biology, and in particular the studies of one particular biological species. (shrink)

The high rates of attrition that occur in drug development are widely regarded as problematic, but the failure of well-designed studies benefits both researchers and healthcare systems by, for example, generating evidence about disease theories and demonstrating the limits of proven drugs. A wider recognition of these benefits will help the biomedical research enterprise to take full advantage of all the information generated during the drug development process.

If SAMCRO can legitimately declare war, then the Sons of Anarchy may still be bad boys, but at least they' are not immoral butchers. The just war theory spells out the criteria that must be met for the use of armed force to be morally justified. They are: Just Cause, Proportionality, Necessity, Right Authority, and Likelihood of Success. To be just, a war must fulfill all six criteria. The chapter presents arguments that suggest, in principle at least, that SAMCRO does (...) have the authority to declare war against an adversary. The club is not so different from existing political institutions. Like all great television, Sons of Anarchy can teach us a lot about the real world. We do not need to condone everything SAMCRO does. But we should be careful not to condemn everything the club does either, even when it resorts to violence. (shrink)

The postulates of rational preference suggested by Von Neumann and Morgenstern have been defended as descriptive or empirical generalizations and as normative principles. It is argued that the postulates are inaccurate empirical generalizations and unacceptable normative principles.