Notions such as terroir and “Slow Food,” which originated in Mediterranean Europe, have emerged as buzzwords around the globe, becoming commonplace across Europe and economically important in the United States and Canada, Latin America, Africa, and Asia. Given the increased global prominence of terroir and regulatory frameworks like geographical indications, we argue that the associated conceptual tools have become more relevant to scholars working within the “alternative food networks” framework in the United States and United Kingdom. Specifically, the Local Agrifood (...) Systems perspective, first articulated in 1996 by French scholars, seeks to understand the relationship between the development of local food systems and specific territories. We review the empirical and theoretical literature that comprises each of these perspectives, highlighting three areas in which SYAL scholarship may be relevant to AFN researchers. First, while AFN scholars tend to understand the “local” in terms of positionality, in a distributionist sense, SYAL studies frame local food systems as anchored within particular territories. Second, SYAL research places significant emphasis on collectivity, both in terms of collective institutions and shared forms of knowledge and identity. Third, although both perspectives are framed in opposition of the industrialization of the global food system, AFN scholars focus more on alternative distribution schemes, while SYAL researchers favor territorially anchored structures. (shrink)

The article proposes systematisation and development of the discourse of the East European methodological traditions regarding application of the systematic approach as a way of subject localisation in psychological research. In particular, the author’s version of systematic localisation of psychological research subjects by means of structural and ontological visualisations has been developed. The procedure proposed for systematic localisation of the researched subject includes four subsequent stages: 1) fixation of the borders and structure of the ontological field which is being studied; (...) 2) segment analysis of the obtained structure; 3) study of specifics and contents of structural and functional ties; 4) visual mapping of genesis of the core processes. The article describes specifics of application of systematic localisation of the subject of research at the example of such researched object as personal socialisation. (shrink)

In the vision of ubiquitous computing it should be possible to create situational and context-aware applications of the internet. But there is a conflict between the global claim of the system and the context-aware local application. First of all it must be clear, what context means. Is the context determined by the material local environment or by the special intention of a person’s action. What role do cultural factors with their historical implications and scales of value play? The meaning of (...) locality depends on the definition of the term context. Thus the term locality specifies an analogy to the term ‘context’. It is necessary especially to also clarify categories like “Leib” and “Lebenswelt”. Finally it is pointed out that special claims of ubiquitous computing like the idea of a global world-model are untenable. Though ubiquitous computing technologies are calm and invisible, it is important to make visible their components. The antagonism between localisation and globalisation shows the real potential of, as well as the claims of, ubiquitous computing. (shrink)

The indexing systems used to systematise our knowledge about a domain tend to have an evaluative character: they represent some things as more important, general, complex, or central than others. They are also imperfect and can misrepresent something as more or less important, etc., than it really is. Such distortions mostly result from mistakes made due to lack of time or resources. In some cases they follow systematic patterns which can reveal the implicit judgements and values shared within a community (...) who maintains and uses an index. I focus on the example of PhilPapers, the largest database of philosophy texts available, to show how the arrangement of categories and the way items are assigned to them, can effectively marginalise certain topics, authors, and entire traditions. I draw attention to such issues as: ordering, size and depth of categories, the use of miscellaneous categories, localising indexes in category names, and assigning items to some but not other categories. I suggest that such structuring of the index can have an impact on users, normalising marginalisation and contributing to the perpetuation of inequalities. I conclude by offering some suggestions for improvement which might help our databases flourish and become even more useful. (shrink)

This paper discusses Freud's model of the psychical apparatus in the “Project”, and concludes that it is a remarkably sophisticated work which even today is still highly relevant to neuropsychological theorising. Freud rejects the notion that what happens in the brain can be clearly localised in space and time. This anticipates the notion of a distributed system found in recent developments in computing (“neural net works”) and in Derrida's conception of systems characterised by différance. Every part of such a system (...) is constituted by its relation to the rest of the system. Although such systems are spatio-temporal, processes occur ring in them can not be pinpointed in space and time. Against the common charge that Freud has a passive hydraulic-reflex model of the psychical apparatus, the authors argue that Freud presents it as an open, complex, self-organising system. Ricoeur's (1972) claim that the model of the psychical apparatus in the “Project” is essentially solipsistic, is accordingly rejected. In conclusion the authors explain why they prefer the model in the “Project” to the more linear model found in Ch. VII of the Traumdeutung. S. Afr. J. Philos. Vol.20(3) 2001: 1- 21. (shrink)

Data production in experimental sciences depends on localised experimental systems, but the epistemic properties of data transcend the contingencies of the processes that produce them. Philosophers often believe that experimental systems instantiate but do not produce the epistemic properties of data. In this paper, we argue that experimental systems' local functioning entails intrinsic capacities to produce the epistemic properties of data. We develop this idea by applying Derrida's model of arche-writing to study a case of theory-oriented experimental practice. Derrida's model (...) relativises or dissolves the conceptual distinction between the moment of data production and a subsequent moment of data dissemination. It thus has consequences for understanding both data production (despite being intrinsically local, data production a priori generates transferrable and modellable information) and data dissemination (when modelling information, researchers needs to refer this information to the context of its production). We study a case of data production in a non-exploratory experimental system designed to test a pre-existing hypothesis in visual neuroscience. A case of theory-oriented experimental practice should allow us to identify the autonomous functioning of experimental systems in data production more clearly, insofar as it allows us to study the limits of pre-existing theory in the activities of these systems. We suggest that pre-existing concepts, hypotheses and theories condition the relevance but not the production of experimental data. (shrink)

We consider consciousness attributed to systems in space-time which can be purely physical without biological background and focus on the mathematical understanding of the phenomenon. It is shown that the set theory based on sets in the foundations of mathematics, when switched to set theory based on ZFC models, is a very promising mathematical tool in explaining the brain/mind complex and the emergence of consciousness in natural and artificial systems. We formalise consciousness-supporting systems in physical space-time, but this is localised (...) in open domains of spatial regions and the result of this process is a family of different ZFC models. Random forcing, as in set theory, corresponds precisely to the random influence on the system of external stimuli, and the principles of reflection of set theory explain the conscious internal reaction of the system. We also develop the conscious Turing machines which have their external ZFC environment and the dynamics is encoded in the random forcing changing models of ZFC in which Turing machines with oracles are formulated. The construction is applied to cooperating families of conscious agents which, due to the reflection principle, can be reduced to the implementation of certain concurrent games with different levels of self-reflection. (shrink)

Au XIXe siècle, la question de la relation de l'âme au corps est profondément renouvelée par les travaux psychologiques allemands. Cette nouvelle manière d'envisager le rapport du psychique au physique participe de l’apparition d’un paradigme cognitiviste où les phénomènes mentaux sont considérés comme des entités isolables, objectivables et corrélables à l’activité de substrats neuraux particuliers. Les psychologues allemands sont confrontés au problème de la corrélation de la vie psychique et du système nerveux (localisation des phénomènes mentaux et nature de ce (...) rapport de corrélation) et proposent une réflexion approfondie sur le déterminisme neural et l’émergence des processus psychiques. (shrink)

En 1810, Gall et Spurzheim posent le diagnostic suivant : la piètre connaissance du substrat cérébral des facultés mentales doit être imputée à la longue inféodation de l’anatomie par la métaphysique. Dans le présent article, nous interrogeons un tel jugement historique à partir du Discours sur l’anatomie du cerveau de Niels Steensen. La présentation des « systèmes » de localisation cérébrale que Steensen critique (celui des « Anciens », celui de Thomas Willis et celui de Descartes) nous permettra d’abord (...) de brosser un tableau des différentes conceptions possibles du « siège de l’âme » au XVIIe siècle. Nous montrerons ensuite comment, dans ces trois cas de figure, la mise en correspondance d’une anatomie neurocérébrale lacunaire et d’une topique des grandes facultés mentales conduit à postuler que telle ou telle partie cérébrale est le siège de la mémoire, celui de l’imagination ou encore celui du sens commun. Enfin, nous montrerons que c’est au nom de la science anatomique, restreinte à ce qui peut être attesté par des témoins oculaires, que Steensen a écarté le principe même des localisations cérébrales. (shrink)

The systems T N and T M show that necessity can be consistently construed as a predicate of syntactical objects, if the expressive/deductive power of the system is deliberately engineered to reflect the power of the original object language operator. The system T N relies on salient limitations on the expressive power of the language L N through the construction of a quotational hierarchy, while the system T Mrelies on limiting the scope of the modal axioms schemas to the sublanguage (...) L infM +, which corresponds exactly with the restrictive hierarchy of L N. The fact that L infM + is identical to the image of the metalinguistic mapping C + from the normal operator system into L M reveals that iterated operator modality is implicitly hierarchical, and that inconsistency is produced by applying the principles of the modal logic to formulas which have no natural analogues in the operator development. Thus the contradiction discovered by Montague can be diagnosed as the result of instantiating the axiom schemas with modally ungrounded formulas, and thereby adding radically new modal axioms to the predicate system.The predicate treatment of necessity differs significantly from that of the operator in that the cumulative models for the predicate system are strictly first-order. Possible worlds are not used as model-theoretic primitives, but rather alternate models are appealed to in order to specify the extension of N, which is semantically construed as a first-order predicate. In this manner, the intensional aspects of modality are built into the mode of specifying the particular set of objects which the denotation function assigns to N, rather than in the specification of the basic truth conditions for modal formulas. Intensional phenomena are thereby localised to the special requirements for determining the extension of a particular predicate, and this does not constitute a structural modification of the first-order models, but rather limits the relevant class of models to those which possess an appropriate denotation function. (shrink)

As we move around in our environment, and interact with it, many of the most important problems we face involve the processing of spatial information. We have to be able to navigate by perceiving and remembering the locations and orientations of the objects around us relative to ourself; we have to sense and act upon these objects; and we need to move through space to position ourselves in favourable locations or to avoid dangerous ones. While this appears so simple that (...) we don't even think about it, the difficulty of solving these problems has been shown in the repeated failure of artificial systems to perform these kinds of tasks efficiently. In contrast, humans and other animals routinely overcome these problems every single day. This book examines some of the neural substrates and mechanisms that support these remarkable abilities. The hippocampus and the parietal cortex have been implicated in various core spatial behaviours, such as the ability to localise an object and navigate to it. Damage to these areas in humans and animals leads to impairment of these spatial functions. This collection of papers, written by internationally recognized experts in the field, reviews the evidence that each area is involved in spatial cognition, examines the mechanisms underlying the generation of spatial behaviours, and considers the relative roles of the parietal and hippocampal areas, including how each interacts with the other. The papers integrate a wide range of theoretical and experimental approaches, and touch on broader issues relating to memory and imagery. As such, this book represents the state of the art of current research into the neural basis of spatial cognition. It should be of interest to anyone - researchers or graduate students - working in the areas of cognitive neuroscience, neuroanatomy, neuropsychology, and cognition generally. (shrink)

A significant factor undermining real racial reconciliation in post-1994 South Africa is widespread resistance to shared historical responsibility amongst South Africans racialised as white. In response to the need for localised ‘white work’, this article aims to contribute to the uprooting of white denialism, specifically amongst Afrikaans-speaking Christians from Reformed backgrounds. The point of entry is two underexplored, challenging, contextualised crucifixion paintings, namely, Black Christ and Cross-Roads Jesus. Drawing on critical whiteness studies, extensive local and international experience as a ‘participatory’ (...) facilitator of conflict transformation and his particular embodiment, the author explores the creative unsettling potential of these two prophetic ‘icons’. Through this incarnational, phenomenological, diagnostic engagement with Black Christ, attention is drawn to the dynamics of family betrayal, ‘moral injury’ and idolisation underlying ‘white fragility’. ‘White fatigue’ is challenged by stressing the Biblical nature of Cross-Roads Jesus’ confrontational, ‘ugly’ portrayal of the systemic violence of apartheid and colonialism. It is also argued that a combination of Louw’s shocking portrayal of an enraged, emaciated township Jesus with the explicit depiction of white historical responsibility in Black Christ increases the counter-cultural potential of these icons to disrupt denial amongst white South African Christians. However, the realisation of this potential will require the cultivation of more capacity to work creatively with the intense emotional, moral, spiritual discomfort brought to the surface by this type of religious icon.Contribution: The article argues for a contextualised, South African engagement with the crucifixion of Christ, through an embodied interpretation of two anti-apartheid religious paintings. It makes a contribution to critical whiteness studies and practical theology and thus fits into the interdisciplinary, hermeneutical scope of HTS. (shrink)

Face à la diversité et à la complexification des modes de formalisation, une épistémologie des méthodes scientifiques doit confronter directement ses analyses à une pluralité d’études de cas comparatives. C’est l’objectif de cet ouvrage. -/- Aussi, dans une première partie, propose-t-il d’abord une classification large et raisonnée des différentes fonctions de connaissance des théories, des modèles et des simulations (de fait, cette partie constitue un panorama d’épistémologie générale particulièrement poussé). C’est ensuite à la lumière de cette classification que les deux (...) parties centrales analysent et distinguent les assises conceptuelles et épistémologiques des principaux types de formalisation en géographie avant et après l’ordinateur (théories des localisations, modèles gravitaires, loi rang-taille). En employant toujours la même méthode analytique et comparative, la dernière partie se concentre sur l’explication épistémologique des trois révolutions computationnelles récentes : l’analyse des données, la présentation des données et enfin l’analyse par simulation computationnelle. -/- Au travers de cette enquête approfondie, la géographie apparaît non seulement comme une discipline carrefour, ayant pour cela donné des exemples de presque tous les types de modèles scientifiques, mais aussi comme une science innovante en termes épistémologiques. Car ce qui a d’abord été pour elle un frein à la formalisation -– sa sensibilité au caractère multifactoriel comme à la dimension irréductiblement spatiale des phénomènes sociaux – et qui l’obligea longtemps à inféoder ses théories et modèles à des disciplines plus aisément formalisables comme la géomorphologie, l’économie, la sociologie, la démographie, ou bien encore la thermodynamique et la théorie des systèmes, devient aujourd’hui un atout dès lors que, parmi les sciences humaines et sociales, elle peut développer une épistémologie non seulement pluraliste mais aussi combinatoire et intégrative. -/- Préface de Denise Pumain (Université Paris 1). (shrink)

La notion de lieu occupe dans le système cartésien une place stratégique : elle en manifeste la singularité tant dans le domaine de la physique que dans celui de la métaphysique. En physique, les difficultés sont nombreuses : comment Descartes parvient-il à édifier une philosophie naturelle qui produit, notamment, les lois du choc et celle de la chute des graves, dans un cadre conceptuel qui nie l'existence du vide ainsi que celle de lieux différents? Jusqu'à quel point peut-on parler d'une (...) mathématisation du réel pour un corps de doctrine aussi peu algébrique que possible? Le spectre du roman cartésien doit être chassé afin de saisir la science cartésienne dans sa nouveauté radicale. Mais dès lors que l'on s'interroge sur les motifs conceptuels qui empêchent Descartes d'élaborer une mathématisation du réel, dont la Géométrie semble lui donner les moyens et les Regulae la méthode, on est conduit à préciser la nature des procédures résolutoires de la pensée, leur portée et leurs limites et, ainsi, à entrer de plain-pied dans le champ de la mathématique, tout d'abord, puis dans celui de la métaphysique. Dire ce qu'est et ce que peut un corps s'énonce à partir du savoir de ce qu'est et de ce que peut l'esprit. En effet, Descartes attribue à l'esprit la force et la puissance, non seulement d'inventer et de produire du nouveau, mais également celle, très concrète, d'imprimer une nouvelle détermination aux mouvements des esprits animaux. On peut considérer que la force chez Descartes est indexée au spirituel plutôt qu'au corporel et qu'en dehors de la question singulière de l'Eucharistie, elle n'est efficace qu'à la condition de ne pas être localisée stricto sensu en termes de lieu : Dieu agit dans le monde pour autant qu'il n'en fait pas partie et la glande pinéale est le siège principal de l'âme, sedes et non pas locus. Cette lecture de l'œuvre cartésienne trouve ainsi dans la notion de lieu un thème d'étude particulièrement fécond, dans la mesure où elle est mobilisée à la fois dans la physique et les mathématiques cartésiennes, mais également dans la question de la localisation de Dieu dans le monde, dans celle du Christ sous les espèces consacrées, et dans celle de l'âme dans le corps. Ainsi d'un lieu à un autre, nous sommes conduits au cœur du système cartésien, par un mouvement d'approfondissement réciproque des perspectives. (shrink)

This book presents fresh insights into analogue quantum simulation. It argues that these simulations are a new instrument of science. They require a bespoke philosophical analysis, sensitive to both the similarities to and the differences with conventional scientific practices such as analogical argument, experimentation, and classical simulation. -/- The analysis situates the various forms of analogue quantum simulation on the methodological map of modern science. In doing so, it clarifies the functions that analogue quantum simulation serves in scientific practice. To (...) this end, the authors introduce a number of important terminological distinctions. They establish that analogue quantum ‘computation' and ‘emulation' are distinct scientific practices and lead to distinct forms of scientific understanding. The authors also demonstrate the normative value of the computation vs. emulation distinction at both an epistemic and a pragmatic level. -/- The volume features a range of detailed case studies focusing on: i) cold atom computation of many-body localisation and the Higgs mode; ii) photonic emulation of quantum effects in biological systems; and iii) emulation of Hawking radiation in dispersive optical media. Overall, readers will discover a normative framework to isolate and support the goals of scientists undertaking analogue quantum simulation and emulation. This framework will prove useful to both working scientists and philosophers of science interested in cutting-edge scientific practice. (shrink)

Desktop computerisation is a widespread phenomenon that affects many women office workers. So far, much of the discussion of this topic treats these workers as ‘users’ while the need for them to (re)design their work and information systems tends to be ignored.This paper applies both conventional and social analytic notions of information systems design to archetypal secretarial work groups, and argues that hitherto under-recognised elements of system design are endemic to desktop computerisation. Case studies which examine how office groups have (...) created information systems and associated work practices, largely through their own efforts, illustrate how this design work can be accomplished. The informal, localised processes of collaborative problem solving, development and sharing of local expertise are important ingredients in this achievement. Broader mobilisation efforts can also play a role. (shrink)

GRW Theory postulates a stochastic mechanism assuring that every so often the wave function of a quantum system is `hit', which leaves it in a localised state. How are we to interpret the probabilities built into this mechanism? GRW theory is a firmly realist proposal and it is therefore clear that these probabilities are objective probabilities (i.e. chances). A discussion of the major theories of chance leads us to the conclusion that GRW probabilities can be understood only as either single (...) case propensities or Humean objective chances. Although single case propensities have some intuitive appeal in the context of GRW theory, on balance it seems that Humean objective chances are preferable on conceptual grounds because single case propensities suffer from various well know problems such as unlimited frequency tolerance and lack of a rationalisation of the principal principle. (shrink)

This paper is about mechanisms and models, and how they interact. In part, it is a response to recent discussion in philosophy of biology regarding whether natural selection is a mechanism. We suggest that this debate is indicative of a more general problem that occurs when scientists produce mechanistic models of populations and their behaviour. We can make sense of claims that there are mechanisms that drive population-level phenomena such as macroeconomics, natural selection, ecology, and epidemiology. But talk of mechanisms (...) and mechanistic explanation evokes objects with well-defined and localisable parts which interact in discrete ways, while models of populations include parts and interactions that are neither local nor discrete in any actual populations. This apparent tension can be resolved by carefully distinguishing between the properties of a model and those of the system it represents. To this end, we provide an analysis that recognises the flexible relationship between a mechanistic model and its target system. In turn, this reveals a surprising feature of mechanistic representation and explanation: it can occur even when there is a mismatch between the mechanism of the model and that of its target. Our analysis reframes the debate, providing an alternative way to interpret scientists’ mechanism-talk , which initially motivated the issue. We suggest that the relevant question is not whether any population-level phenomenon such as natural selection is a mechanism, but whether it can be usefully modelled as though it were a particular type of mechanism. (shrink)

Abstract The Duhem?Quine thesis is generally presented as the radical underdetermi? nation of a theory by experimental evidence. But there is a much?neglected second aspect, i.e. the coherence or interrelatedness of the conceptual components of a theory. Although both Duhem and Quine recognised this aspect, they failed to see its consequences: it militates against the idea of radical underdetermination. Because scientific theories are coherent conceptual systems, empirical evidence penetrates, as it were, the periphery and allows the localisation of central, not (...) just peripheral hypotheses. There is then no reason to deny the existence of crucial experiments. Both these ideas are denied in the Quine?Duhem thesis. A discussion of the famous Stem?Gerlach experiment and the role of fundamental physical constants shows, however, that localisation is not only possible but essential for the validity of scientific theories. Quine's famous ?latitude of choice? turns out to be severely restricted. (shrink)

The paper takes up Bell's “Everett theory” and develops it further. The resulting theory is about the system of all particles in the universe, each located in ordinary, 3-dimensional space. This many-particle system as a whole performs random jumps through 3N-dimensional configuration space – hence “Tychistic Bohmian Mechanics”. The distribution of its spontaneous localisations in configuration space is given by the Born Rule probability measure for the universal wavefunction. Contra Bell, the theory is argued to satisfy the minimal desiderata for (...) a Bohmian theory within the Primitive Ontology framework. TBM's formalism is that of ordinary Bohmian Mechanics, without the postulate of continuous particle trajectories and their deterministic dynamics. This “rump formalism” receives, however, a different interpretation. We defend TBM as an empirically adequate and coherent quantum theory. Objections voiced by Bell and Maudlin are rebutted. The “for all practical purposes”-classical, Everettian worlds exist sequentially in TBM. In a temporally coarse-grained sense, they quasi-persist. By contrast, the individual particles themselves cease to persist. (shrink)

Élie HALÉVY (1870-1937), philosophe et historien des idées, fut professeur à l'École libre des sciences politiques, l'ancêtre de l'actuel Sciences Po. Comme son autre grand ouvrage, l'Histoire du peuple anglais au XIXe siècle, paru en six tomes de 1913 à 1932, les trois tomes de La formation du radicalisme philosophique, parus en 1901 pour les deux premiers et en 1904 pour le troisième, reflètent pour partie ses enseignements de l'Ecole libre consacrés à l'histoire britannique. Le premier tome, La jeunesse de (...) Bentham 1776-1789, étudie la doctrine utilitariste non seulement chez celui qu'on regarde comme son fondateur principal, Jeremy Bentham, mais aussi chez les nombreux auteurs qui, en Grande-Bretagne et sur le continent, en dessinèrent avant lui les contours. Le deuxième tome, L’évolution de la doctrine utilitaire de 1789 à 1815, montre comment l'utilitarisme revêtit la forme non seulement d'une école de pensée, mais aussi d'un mouvement pour la réforme économique, sociale et politique. Le rôle coordonnateur nouveau de James Mill, ainsi qu'une convergence de vues avec les économistes, qui poussaient dans le sens des réformes, marquèrent notamment cette évolution. Le troisième tome, Le radicalisme philosophique, continue d'étudier la transformation de l'école en mouvement après la fin des guerres napoléoniennes, lorsque celle-ci commence à engranger ses premiers grands succès réformistes. Bentham, James Mill et les autres penseurs utilitaires sont alors réunis sous l'appellation de philosophic radicals. Le terme temporel de l'ouvrage est le Reform Act de 1932, première étape vers la modernisation du système électoral, que la propagande de ce groupe ne contribua pas peu à faire aboutir. Quoique l'ouvrage d'Halévy vaille en premier lieu par l'immense savoir qu'il déploie, et le nombre et l'excellence des citations qu'il propose, il comporte aussi des thèses historiques et philosophiques originales. On peut citer parmi les premières la thèse, qui relie les trois tomes, voulant que l'utilitarisme britannique trouve sa forme achevée dans l'intervention sur la société, lorsqu'il se mue en radicalisme philosophique, et parmi les secondes, la thèse, énoncée au début du premier tome, voulant qu'il existe trois modèles dominants de jonction des intérêts individuels (la fusion sympathique, l'identification naturelle et l'identification artificielle). Une autre grande thèse, à la fois historique et philosophique, affirme en substance que l'économie politique classique serait un département spécialisé de la pensée utilitaire. La question de savoir jusqu'à quel point Smith, Ricardo et Malthus ont pu adhérer au "principe d'utilité" de Bentham est toujours débattue. En même temps que les élucidations apportées à ce principe, elle contribue à expliquer l'intérêt que les historiens de la pensée économique continuent de porter à l'ouvrage. La réédition de La formation du radicalisme philosophique par les Presses Universitaires de France (P.U.F.) a impliqué un effort collectif. Monique Canto-Sperber en a conçu l'idée et assumé la direction, et l'ouvrage a paru en 1995 dans la collection Philosophie morale dont elle avait alors la responsabilité aux P.U.F. Chacun des trois tomes s'accompagne d'une postface, confiée au philosophe Jean-Pierre Dupuy pour le premier, au politologue Pierre Bouretz pour le second, et à l'économiste Philippe Mongin pour le troisième. Un travail de grande ampleur a été requis, d'une part, pour localiser les références de Halévy dans des sources plus récentes que celles dont il disposait, en particulier, s'agissant de Bentham, dans l'édition toujours en cours de ses œuvres, et d'autre part, pour traduire les très nombreux passages que Halévy citait en langue anglaise. Sophie Jallais et Mary Sokol se sont chargées de la première tâche et Jean-Pierre Cléro de la seconde. Prise après quelques années de circulation de l'ouvrage, la décision des P.U.F. d'en pilonner les exemplaires que ses responsables ne rachèteraient pas a semblé compromettre ce vaste travail. Mais grâce aux efforts du site québécois Les classiques des sciences sociales, et de son directeur Jean-Marie Tremblay, il est devenu possible d'accéder aux trois tomes électroniquement. Les adresses en sont : http://classiques.uqac.ca/classiques/halevy_elie/radicalisme_philo_t1/radicalisme_philo_t1.html http://classiques.uqac.ca/classiques/halevy_elie/radicalisme_philo_t2/radicalisme_philo_t2.html http://classiques.uqac.ca/classiques/halevy_elie/radicalisme_philo_t3/radicalisme_philo_t3.html Avant la réédition de 1995, l'ouvrage de Halévy n'était facilement accessible que grâce à la traduction anglaise plusieurs fois rééditée de Mary Morris, The Growth of Philosophic Radicalism, New York, Macmillan, 1928. (shrink)

Language is infused with materiality and should therefore not be considered as an abstract system that is isolated from socio-material reality. Expressions materialise language in social practices, thus providing the necessary basis for languaging activities. For this reason, it makes sense to challenge proponents of orthodox linguistics and others who hold that language can be studied in isolation from its concrete manifestations. By exploring the relation between materiality and linguistic activity, the article extends Malafouris’ Material Engagement Theory while clarifying the (...) phenomenon of ‘linguistic denotation’. In so doing, it critiques orthodox approaches to language which trace denotation to abstract meanings and/or mental representations. The article shows how the denotative aspects of language can be cashed out in non-representational terms and, furthermore, that the interrelation of denotation and materiality is crucial to human material culture in that it allows for material engagements to transcend localised contexts. These engagements become global in Latour’s sense and, in so doing, denotation ceases to demand descriptions in terms of representations. (shrink)

oeuvre posthume d'un logicien humaniste, cette etude se presente avant tout comme un bilan analytique, tout en s'alimentant a l'experience personnelle de l'auteur. Robert Blanche pose d'abord un probleme de recensement et de classement. L'esthetique n'est pas plus la science exclusive du beau que la zoologie n'est la science exclusive du cheval: le sublime, le gracieux, le poetique, d'autres categories encore l'encadrent et forment systeme avec lui, s'organisant en couples antithetiques, en triades, a la limite en rosaces (classique, romantique) intercalees (...) l'une dans l'autre. Revenant sur les categories majeures, Blanche les considere ensuite une a une, chacune ayant sa problematique propre. Le beau, defini avant tout par la nettete d'une forme, maitrise (quand il s'y allie) la dimension de l'affectif et du voluptuaire. A l'inverse, le poetique n'a ni forme geometrique, ni lisibilite immediate et synoptique. Sa forme (son anti-forme) est le vague, le vaporeux. Son lieu d'election est le temps. Vient ensuite le decrescendo qui nous conduit du sublime, dont Blanche rappelle l'essence paradoxale, a la grace, categorie de l'aisance irenique, puis au joli, ou la dimension voluptuaire, le chatouillement des sens, prend toute la place, cotoyant a sa limite inferieure la sensibilite protopathique. Blanche s'interroge enfin sur le rapport entre style et categorie. Un style est un fait historique, localise et date; une categorie, au contraire, est un mode permanent d'appreciation esthetique. (shrink)

The paper considers the problem of how a distributed system of agents (who communicate only via a localised network) might achieve consensus by copying beliefs (copy) from each other and doing some belief pruning themselves (drop). This is explored using a social simulation model, where beliefs interact with each other via a compatibility function, which assigns a level of compatibility (which is a sort of weak consistency) to a set of beliefs. The probability of copy and drop processes occurring is (...) based on the increase in compatibility this process might result in. This allows for a process of collective consensus building whilst allowing for temporarily incompatible beliefs to be held by an agent. (shrink)

Ageing is associated with a decline in autophagy and elevated reactive oxygen species (ROS), which can breach the capacity of antioxidant systems. Resulting oxidative stress can cause further cellular damage, including DNA breaks and protein misfolding. This poses a challenge for longevous organisms, including humans. In this review, we hypothesise that in the course of human evolution selective autophagy receptors (SARs) acquired the ability to sense and respond to localised oxidative stress. We posit that in the vicinity of protein aggregates (...) and dysfunctional mitochondria oxidation of key cysteine residues in SARs induces their oligomerisation which initiates autophagy. The degradation of damaged cellular components thus could reduce ROS production and restore redox homeostasis. This evolutionarily acquired function of SARs may represent one of the biological adaptations that contributed to longer lifespan. Inversely, loss of this mechanism can lead to age‐related diseases associated with impaired autophagy and oxidative stress. (shrink)

Recent studies have recognised the Confucian holistic perspective as transformative in addressing the ecological concerns. This article complements and complicates this line of argument. The aforementioned literature has seldom examined whether or not the Confucian ideal is attainable. Centring on cheng, a Confucian metaphysical concept, this article highlights the struggle between the ideal and the real. The discussion is based on the premise that essential to the current ecological crisis is a need to reconfigure the meaning and purpose of humanity (...) on the planet; utopianism, evoking images of a society radically different from the existing one, has the potential to instigate transformations. Utopias of all kinds encounter the tension between ideal and practice. Webb proposes an analytical framework of utopia-as-system and utopia-as-process. The former stresses an idealised blueprint and the latter attends to localised practice. For any radical change to occur, it is imperative to adopt both. Drawing on the research of ecotopia and edutopia, this article argues that Confucianism has a utopian impetus. As ecological self-understanding, cheng challenges modern assumptions regarding humanity and ecology. The concept represents a model of both utopia-as-system and utopia-as-process, and it has the potential to inspire change. It is, however, not without complication. (shrink)

Molecular and developmental studies of limb pattern formation have recently gained widespread attention. The fact that vertebrate limbs are amenable to both genetic and embryological manipulations has established this model system as a valuable paradigm for studying vertebrate development. Limb buds are polarised along all three major axes and the establishment of the dorso‐ventral (DV) polarity is dependent upon cues localised in the trunk, where a DV ectodermal interface is produced by confrontation of dorsal and ventral identities. By analogy to (...) Drosophila imaginal disc development, this interface has been proposed to determine and position an ectodermal organising centre, the Apical Ectodermal Ridge (AER), controlling limb bud outgrowth. Recent fate mapping studies(1) and studies of genes regulating DV limb polarity(2‐6), AER formation(7,8) and differentiation(9) suggest, however, that DV patterning and AER induction, though coordinately regulated during limb bud outgrowth, may early on be more dissociated than expected. (shrink)

A guaranteed Income scheme is inescapable in this age of information, autonomous labor and human development, but it is also the only possible ecological response to bail out from the productivist consequences of waged labor. Yet, in order to develop an alternative mode of production, one needs to look not only at incomes, but also into production itself, that is of the means of productions as well as of the monetary and commercial flows. In a new, environmentally sound approach towards (...) re-localising the economy, a guaranteed income, municipal co-operatives, and local currency set-ups are necessarily concurrent features towards a new system of production, and new forms of social relations not based on wage labor, in this era of immaterial labor and commercial globalisation. (shrink)

We propose that observables in quantum theory are properly understood as representatives of symmetry-invariant quantities relating one system to another, the latter to be called a reference system. We provide a rigorous mathematical language to introduce and study quantum reference systems, showing that the orthodox “absolute” quantities are good representatives of observable relative quantities if the reference state is suitably localised. We use this relational formalism to critique the literature on the relationship between reference frames and superselection rules, settling a (...) long-standing debate on the subject. (shrink)

I investigate the character of the definite properties defined by the Basic Rule in the Vermaas and Dieks' (1995) version of the modal interpretation of quantum mechanics, specifically for the case of the continuous model of decoherence by Joos and Zeh (1985). While this model suggests that the characteristic length that might be associated with the localisation of an individual system is the coherence length of the state (which converges rapidly to the thermal de Broglie wavelength), I show in an (...) exactly soluble case that the definite properties that are possessed with overwhelming probability in this modal interpretation are delocalized over the entire spread of the state. (shrink)

In The Interface Envelope, James Ash develops a series of concepts to understand how digital interfaces work to shape the spatial and temporal perception of players. Drawing upon examples from videogame design and work from post-phenomenology, speculative realism, new materialism and media theory, Ash argues that interfaces create envelopes, or localised foldings of space time, around which bodily and perceptual capacities are organised for the explicit production of economic profit. Modifying and developing Bernard Stiegler's account of psychopower and Warren Neidich's (...) account of neuropower, Ash argues the aim of interface designers and publishers is the production of envelope power. Envelope power refers to the ways that interfaces in games are designed to increase users perceptual and habitual capacities to sense difference. Examining a range of examples from specific videogames, Ash identities a series of logics that are key to producing envelope power and shows how these logics have intensified over the last thirty years. In turn, Ash suggests that the logics of interface envelopes in videogames are spreading to other types of interface. In doing so life becomes enveloped as the environments people inhabit becoming increasingly loaded with digital interfaces. Rather than simply negative, Ash develops a series of responses to the potential problematics of interface envelopes and envelope power and emphasizes their pharmacological nature. (shrink)

Community informatics and Information and Communications Technology for Development research projects frequently focus on the appropriation of ICTs and the design of information systems to meet the needs of communities. Such projects typically involve a range of participants reflecting different cultures and depend for their success on the ability of the project to bridge differences. Using PROTIC, a 5-year collaborative project between Monash University, Oxfam Australia and Oxfam in Bangladesh as a case study, this paper reflects on the use of (...) a “mainstream” form of participatory action research as a tool capable of engaging in more sustainable projects by helping to identify and to take into account localised or context-specific social and cultural issues in the design of the information system itself, consequently improving the effectiveness and sustainability of the systems developed. The idea of emic understandings of culture have also been used to interpret the project and PAR as an intercultural exchange around developing a community-focussed sociotechnical project. (shrink)

John Hughlings Jackson is a major figure at the origins of neurology and neuroscience in Britain. Alongside his contributions to clinical medicine, he left a large corpus of writing on localisation of function in the nervous system and other theoretical topics. In this paper I focus on Jackson’s “doctrine of concomitance”—his parallelist theory of the mind-brain relationship. I argue that the doctrine can be given both an ontological and a causal interpretation, and that the causal aspect of the doctrine is (...) especially significant for Jackson and his contemporaries. I interpret Jackson’s engagement with the metaphysics of mind as an instance of what I call meta-science—the deployment by scientists of metaphysical positions and arguments which help streamline empirical investigations by bracketing off unanswerable questions and focussing attention on matters amenable to the current tools of experimental research. (shrink)

Directed cell migration is a fundamental component of numerous biological systems and is critical to the pathology of many diseases. Although the importance of secreted chemoattractant factors in providing navigational cues to migrating cells bearing specific chemoattractant receptors is now well‐established, how the function of these factors is regulated is not so well understood and may be of key importance to the design of new therapeutics for numerous human diseases. While regulation of migration clearly takes place on a number of (...) different levels, it is becoming clear that so‐called ‘atypical’ receptors play a role in scavenging, or altering the localisation of, chemoattractant molecules such as chemokines and complement components. These receptors do this through binding and/or internalising their chemoattractant ligands without activating signal transduction cascades leading to cell migration. The atypical chemokine receptor family currently comprises the receptors D6, DARC and CCX‐CKR. In this review, we discuss the evidence from in vitro and in vivo studies that these receptors play a role in regulating cell migration, and speculate that other orphan receptors may also belong to this family. Furthermore, with the advent of gene therapy on the horizon, the therapeutic potential of these receptors in human disease is also considered. BioEssays 29: 237–247, 2007. © 2007 Wiley Periodicals, Inc. (shrink)

This study investigates the significance of understanding police perspectives on community policing as a means of addressing insecurity, particularly within the context of localised and asymmetrical conflicts. It highlights the pivotal role of the police in shaping community security and the substantial impact they can have (positive or negative) in fragile environments. The study contends that the localised nature of the community policing effectively addresses security and development issues and empowering citizens. Qualitative interviews were conducted with senior police in Islamabad, (...) to assess the implementation and potential impacts of community policing in Pakistan’s Federal Capital Territory. The findings reveal how the historical foundations of police structures and operations – which date back to the colonial period – have led to the promotion of fear, mistrust and manipulation under successive regimes. Despite these challenges, the findings are promising highlighting enhanced human security through context-specific community policing. Finally, the paper argues that the movement towards community-oriented policing marks a departure from the control of elites within state systems, and encourages values such as local ownership, social cohesion, mutual engagement, accountability and agency. These developments have profound implications for global security and justice. (shrink)

Le dysfonctionnement, la défectuosité et les erreurs sont des phénomènes qui peuvent aider à mieux comprendre les entités affectées par ces incidents. L’analyse approfondie du fonctionnement et du dysfonctionnement facilite en particulier la découverte, l’explication et la modélisation théorique des structures, fonctions et mécanismes propres à un système. Dans certains cas, les dysfonctionnements sont le seul moyen d’accéder aux processus internes d’un certain système. Le présent essai analyse les méthodes de diverses disciplines tenant compte de dysfonctionnements tels que les mutations, (...) les illusions optiques, les erreurs d’action ou les lapsus linguistiques et identifie les motifs communs aux stratégies de recherche basées sur le dysfonctionnement. Ces stratégies contribuent à la décomposition de systèmes, à la reconstruction de séquences d’événements, à la localisation de sous-systèmes, ainsi qu’au développement et au test d’hypothèses mécanistes. (shrink)

Le dysfonctionnement, la défectuosité et les erreurs sont des phénomènes qui peuvent aider à mieux comprendre les entités affectées par ces incidents. L’analyse approfondie du fonctionnement et du dysfonctionnement facilite en particulier la découverte, l’explication et la modélisation théorique des structures, fonctions et mécanismes propres à un système. Dans certains cas, les dysfonctionnements sont le seul moyen d’accéder aux processus internes d’un certain système. Le présent essai analyse les méthodes de diverses disciplines tenant compte de dysfonctionnements tels que les mutations, (...) les illusions optiques, les erreurs d’action ou les lapsus linguistiques et identifie les motifs communs aux stratégies de recherche basées sur le dysfonctionnement. Ces stratégies contribuent à la décomposition de systèmes, à la reconstruction de séquences d’événements, à la localisation de sous-systèmes, ainsi qu’au développement et au test d’hypothèses mécanistes. (shrink)

Wittgenstein's later rejection of the externalist Tractarian picture of logic according to which all rationally analysable discourse is properly understood as truth-functional rules out any conception of logic as the study of universal features of discourse. Given later references to 'the logic of our language', some conception of logic appears to survive even on Wittgenstein's later view. However, given his rejection of any conception of philosophical theory as explanatory or hypothetical, Wittgenstein seems to be forced into descriptivism. Despite these constraints, (...) I attempt to show that a valuable account of logic consistent with Wittgenstein's critique can be identified. That possibility raises the question: can any conception of formal logic as valuable modulo natural language survive Wittgenstein's later change of heart? Taking Wittgenstein's rejection of Tractarian conceptions seriously, logic is relativised to language-games in general and, perhaps, localised to particular language-games. Looking at logic in this way opens up the possibility of uncovering inferential structures distinct from those which form the traditional logical-epistemological dichotomy. Here I outline a formal logical framework consistent with all of the foregoing points in terms of which analogues of inferential structures (traditional and non-traditional) can be constructed. Taking third-person ascriptions of psychological predicates as a testcase, I try to show that the formal framework (a system of formal dialogue) has a flexibility which augurs well for future logical investigations into linguistic practices without presupposing knowledge of the kinds of inferential structures which such investigations might reveal. Hence, my claim that the system in question represents logic after (the later) Wittgenstein. (shrink)

Wittgenstein's later rejection of the externalist Tractarian picture of logic according to which all rationally analysable discourse is properly understood as truth-functional rules out any conception of logic as the study of universal features of discourse. Given later references to 'the logic of our language', some conception of logic appears to survive even on Wittgenstein's later view. However, given his rejection of any conception of philosophical theory as explanatory or hypothetical, Wittgenstein seems to be forced into descriptivism. Despite these constraints, (...) I attempt to show that a valuable account of logic consistent with Wittgenstein's critique can be identified. That possibility raises the question: can any conception of formal logic as valuable modulo natural language survive Wittgenstein's later change of heart? Taking Wittgenstein's rejection of Tractarian conceptions seriously, logic is relativised to language-games in general and, perhaps, localised to particular language-games. Looking at logic in this way opens up the possibility of uncovering inferential structures distinct from those which form the traditional logical-epistemological dichotomy. Here I outline a formal logical framework consistent with all of the foregoing points in terms of which analogues of inferential structures (traditional and non-traditional) can be constructed. Taking third-person ascriptions of psychological predicates as a testcase, I try to show that the formal framework (a system of formal dialogue) has a flexibility which augurs well for future logical investigations into linguistic practices without presupposing knowledge of the kinds of inferential structures which such investigations might reveal. Hence, my claim that the system in question represents logic after (the later) Wittgenstein. (shrink)

The paper presents a novel take on the character of South Africa’s governance structure. It argues that, insofar as it constitutionally recognises traditional authorities, figures who rule in accordance with idiosyncratic and localised customary laws, as well as instigate a cheek-by-jowl existence of an asymmetrical property law (where in the urban setting land is nominally bought or transferred for sale, but in traditional rural areas granted by the chief), manifest in the differentiated land laws brought about by the Communal Land (...) Rights Act of 2003, is more akin to, and necessitates a definitional alignment with, the federal system of government than a unitary one – or at least a weak “federalism with South African characteristics.”. (shrink)

Cell signalling mediators derived from membrane phospholipids are frequent participants in biological processes. The family of phosphoinositide 3-kinases (PI3Ks) phosphorylate the membrane lipid phosphatidylinositol, generating second messengers that direct diverse responses. These PI3K products are fundamental for leukocyte migration or chemotaxis, a pivotal event during the immune response. This system is therefore of significant biomedical interest. This review focuses on the biochemistry and signalling pathways of PI3K, with particular emphasis on chemokine (chemotactic cytokine)-directed responses. The key objectives of chemotaxis are (...) motility and direction. The latter—direction—requires distinct events at the front and back of a cell. In light of this, the coordinated localisation of signalling factors, an event choreographed by a sharp intracellular gradient of PI3K-derived products, is a common theme. BioEssays 27:153–163, 2005. © 2005 Wiley Periodicals, Inc. (shrink)

L'offre de services de géolocalisation via un téléphone mobile implique de connaître la localisation et l'identifiant du téléphone, donc de collecter des données relatives à un utilisateur identifié ou identifiable. À ce titre, la loi Informatique et Libertés exige que l'utilisateur consente en toute transparence à bénéficier d'un service géolocalisant et que ses données de localisation soient détruites ou anonymisées une fois la prestation fournie. Si, dans certains cas, l'utilisateur aspire à être localisé, dans d'autres cas, la personne concernée ignore (...) que sa position géographique est connue de tiers. Cette traçabilité subie laisse entrevoir de redoutables perspectives de contrôle ou d'abus tant de la part des services répressifs que des entreprises. L'enjeu ne porte pas uniquement sur les risques d'atteinte à la liberté d'aller et venir, et au respect de la vie privée. De façon plus pernicieuse, l'autonomie informationnelle et décisionnelle du citoyen peut être remise en cause.Location Based Services are information services that can be accessed with mobile phones. They rely on the system s knowledge of the geographical position and the identifier of the phone being used, and therefore on collecting data on an identified or identifiable user. In this respect, the French data protection act stipulates that users agree to be supplied with an LBS service on a fully transparent basis and that their location data must be erased or made anonymous once the service has been provided. In some cases, locationbased services are provided on the user s own request, but in other cases, the individual concerned is unaware of the fact that third parties know where s/he is. This creates potentialfor surveillance and misuse on the part of both police and businesses. What is at stake here is not only the right of individuals to freedom of movement and to privacy but also, and more perniciously, citizens autonomy with regard to information and decision-making. (shrink)

Upon previous research, the matrilineal system seems to oppose Islamic teaching. However, the matrilineal system practiced by the Minangkabau society in West Sumatra, Indonesia has its uniqueness. Thus, this study aims to examine the correlation between the Qur’an and gender roles within the context of Minangkabau customs, specifically focusing on the matrilineal aspect. The present study employs qualitative methods for conducting library research through critical analysis. This study discovered that the matrilineal system practiced by the Minangkabau society aligns with Qur’anic (...) teachings that respect the position of women in Islam. In the matrilineal system of Minangkabau, women hold significant strength and play an influential role in cultural and traditional practices. The Minangkabau tribe’s matrilineal system encompasses three key elements: marriage, inheritance and offspring. The marriage system is exogamous. Additionally, the practice of marriage is localised, with the husband typically residing in the wife’s household. Their inheritance is divided into pusako tinggi [from ancestors from generation to generation] and pusako randah (from the efforts of married couple). Women get pusako tinggi as they serve as protectors and a symbol of their community. In comparison, men take the responsibility of overseeing its preservation to prevent any form of misuse. Pusako randah is distributed as Islamic teaching. Lineage determination is primarily based on paternal lineage, aligning with Islamic teaching. Upon comprehensive analysis, it becomes evident that there is no conflict between the matrilineal system and Islamic teachings, particularly concerning principles of gender equality. Both women and men have significant roles, as the Qur’an provides extensive explanations regarding gender equality.Contribution: This research holds significant findings in establishing a great relation between Islamic teachings based on the Qur’an and the matrilineal principles practiced by the Minangkabau tribe. (shrink)

Young people are increasingly required to demonstrate civic engagement in their communities and help deliver the aspirations of localism and Big Society. Using an ecological systems approach this paper explores the experiences of different groups of young people living in areas of socio-economic disadvantage. Using volunteering as an example of civic engagement it is shown that barriers and motivators for young people stem from within the micro, meso, exo and macrosystems, and that these interact with each other, and with bio-psychological (...) factors within individuals, to bring about differential opportunities and outcomes for young people. Through examining the experiences of three different groups of young people placed within socio-economically disadvantaged communities, considerable variation in levels of civic engagement are identified and it is suggested that some young people's lived experiences are resulting in decisions to civically disengage. It is argued that young people need to benefit from genuine opportunities to develop self-efficacy if they are to respond to the demands of Big Society aspirations for localised decision-making. (shrink)

There are some conspicuous differences between the sensibilities of cutaneous and visceral tissues: (1) Direct trauma, which readily produces pain when applied to the skin, is mostly without effect in healthy visceral tissue. (2) Pain that arises from visceral tissues is initially often poorly localised and diffuse. (3) With time, visceral pains are often referred to more superficial structures. (4) The site of referred pain may also show hyperalgesia. (5) In disease states, the afflicted viscera may also become hyperalgesic. In (...) this target article, I consider to what extent differences in the physiology, anatomy, and chemistry of peripheral processing systems explain these different sensibilities. In almost every aspect, there are subtle differences in the properties of the processing mechanisms for cutaneous and visceral information. These may arise because of distinct developmental cues operating in the two domains. Many of the differences between visceral and cutaneous afferents are quantitative rather than qualitative. The quantitative differences, for example in the density of afferent innervation, can be large. The quantitative differences in the numbers of afferents alone may be a sufficient explanation for some aspects of the differential sensibility, for example, the poor localisation of sensation and the apparent insensitivity to focal yet tissue- damaging stimuli. In addition, the few clear qualitative differences apparent in the innervations of the two tissue types may be of special importance. That the encoding of visceral nociceptive events may occur by an intensity mechanism rather than a specificity mechanism could be the key difference in viscerosensory and somatosensory processing. (shrink)

It is shown that the uncertainty principle has nothing directly to do with the non-localisability of position and momentum for an individual system on the quantum logical view. The product Δ x· Δ p for localisation of the ranges of position and momentum of an individual system→ ∞ , while the quantities Δ X and Δ P in the uncertainty principle $\Delta X\cdot \Delta P\geq \hslash /2$ , must be given a statistical interpretation on the quantum logical view.

Depuis Léon Brunschvicg s’est établie une sorte de lieu commun de l’interprétation de la métaphysique de Leibniz, dont la cohérence serait compromise par la contradiction entre la monade, pour qui l’espace est idéal, et la « monadologie » ou système de toutes les monades coexistantes, qui présupposerait un réalisme de l’espace. Dans cet article, l’argument de Brunschvicg est reconstitué, puis critiqué par la restitution de la pensée réelle de Leibniz sur les rapports entre monade et espace : on ne doit (...) en aucun cas se représenter la pluralité des monades comme une multiplicité spatiale – l’espace est un ordre non des substances simples, mais des phénomènes, – seule l’union constante et universelle de chaque monade à un corps organique permet de parler d’un « point de vue », qui n’est autre que la localisation de ce corps parmi les autres et non de la monade qui, en tant que telle, n’a pas de lieu. (shrink)

Research represents an essential component of the response to infectious disease outbreaks and to other public health emergencies, whether they are localised, of international concern, or global. Research conducted in such contexts also comes with particular ethics challenges, the awareness of which has significantly grown following the Ebola outbreak in West Africa, the Zika outbreak in Latin America and the COVID-19 pandemic. These challenges include the need for implementing meaningful community engagement with the researched communities, not just to build unidirectional (...) trust towards the research team, but to achieve a genuine and mutually respectful partnership before, during and after the research. Here, we describe the real-life experience of 10 well-established research clinics in Nairobi, where a successful experience of community engagement linking prevention and care to research was interrupted during the COVID19 pandemic. We contrast this experience with the concept and processes of community engagement as described in selected scientific manuscripts and guidelines, to formulate some conclusions and recommendations. We contend that more action is needed, from research ethics committees and other key-research stakeholders, to align policies and practices with ethics guidance and with evidence-based recommendations from the academic literature, to achieve meaningful community engagement during emergency research, irrespective of the scale and location of an outbreak or public health crisis. Failure to do so, will aggravate the (postcolonial) asymmetries of power in global health and local systems. (shrink)