In the course of the long 18th century, medical theory and theories underwent profound changes. These in turn reflected discontinuities and often conflicting assumptions and premises, engendering divergent concepts of physiology and pathology. However, most theoretical considerations were only very inconsistently and partially reflected in therapeutic practice, which continued to be governed by experience with traditional and known medicinals and by patient expectations regarding provider practices. Additional factors in therapeutic decision making were economic considerations and preferences for particular therapies in (...) certain social and religious networks. The present volume deals with some aspects of this complex relationship between medical theory and therapeutic practice, using a transatlantic perspective. Individual essays reflect the current state of historical research in Germany, the US and Great Britain. (shrink)

Radioactivity accompanied by ionizing radiation has always existed on the Earth, as well as in space, and so in every living tissue there are traces of radioactivity. With the discovery of the said radiation and identifying its effects on the human body, the fear of this phenomenon appeared. At high doses radiation causes serious tissue damages, while at small doses it can cause cancer and induce genetic defects. The best antidote for fear is knowledge. It is important to know the (...) margins safety of radiation for human life. As a result, the topic of radioactive contamination of the environment has now become one of the most significant. In recent years the radon problem is a subject of a wide debate of geologists, geophysicists, ecologists, physicians, specialists in radiometry, and, of course, philosophers and sociologists, since the need for assessing the potential radon danger concerns human lives, human functions in society, and human future. (shrink)

How are non-declarative sentences understood? How do they differ semantically from their declarative counterparts? Answers to these questions once made direct appeal to the notion of illocutionary force. When they proved unsatisfactory, the fault was diagnosed as a failure to distinguish properly between mood and force. For some years now, efforts have been under way to develop a satisfactory account of the semantics of mood. In this paper, we consider the current achievements and future prospects of the mood-based semantic programme.

mechanism" is frequently encountered in the social science literature, but there is considerable confusion about the exact meaning of the term. The article begins by addressing the main conceptual issues. Use of this term is the hallmark of an approach that is critical of the explanatory deficits of correlational analysis and of the covering-law model, advocating instead the causal reconstruction of the processes that account for given macro-phenomena. The term "social mechanisms" should be used to refer to recurrent processes generating (...) a specific kind of outcome. Explanation of social macro-phenomena by mechanisms typically involves causal regression to lower-level elements, as stipulated by methodological individualism. While there exist a good many mechanism models to explain emergent effects of collective behavior, we lack a similarly systematic treatment of generative mechanisms in which institutions and specific kinds of structural configurations play the decisive role. Key Words: causal regression • correlational analysis • emergent effects • micro-macro processes • social mechanisms • structural determinants. (shrink)

When people speak, their words never fully encode what they mean, and the context is always compatible with a variety of interpretations. How can comprehension ever be achieved? Wilson and Sperber argue that comprehension is an inference process guided by precise expectations of relevance. What are the relations between the linguistically encoded meanings studied in semantics and the thoughts that humans are capable of entertaining and conveying? How should we analyse literal meaning, approximations, metaphors and ironies? Is the ability (...) to understand speakers' meanings rooted in a more general human ability to understand other minds? How do these abilities interact in evolution and in cognitive development? MEANING AND RELEVANCE sets out to answer these and other questions, enriching and updating relevance theory and exploring its implications for linguistics, philosophy, cognitive science and literary studies. (shrink)

Precision medicine and digital phenotyping are two prominent data-based approaches within digital medicine. While precision medicine historically used primarily genetic data to find targeted treatment options, digital phenotyping relies on the usage of big data deriving from digital devices such as smartphones, wearables and other connected devices. This paper first focusses on the aspect of data type to explore differences and similarities between precision medicine and digital phenotyping. It outlines different ways of data collection and production and the consequences thereof. (...) Second, it shows how these sorts of data influence dominant beliefs in the field: The field of precision medicine relying on the dominant understanding of ‘genetic determinism’ imported from genetics, digital phenotyping building on the logic of ‘data fundamentalism’. In the end, the analysis shows how digital data informs potentials as well as challenges of precision medicine and digital phenotyping: a better health care for individuals connected with individualisation and responsibilisation for all, with a prognosed shift from reactive to preventive medicine. Additionally, data-based approaches might facilitate epistemological and ontological redirections for the whole field of medicine that will also affect knowledge production and a reassessment of the value of different types of knowledge with all its consequences. Institutionally, it might lead to shifts in distribution of power to experts in big data related technologies, i.e. private companies. (shrink)

This article explores three ways in which physics may involve counterpossible reasoning. The first way arises when evaluating false theories: to say what the world would be like if the theory were true, we need to evaluate counterfactuals with physically impossible antecedents. The second way relates to the role of counterfactuals in characterizing causal structure: to say what causes what in physics, we need to make reference to physically impossible scenarios. The third way is novel: to model metaphysical dependence in (...) physics, we need to consider counterfactual consequences of metaphysical impossibilities. Physics accordingly bears substantial and surprising counterpossible commitments. (shrink)

This paper explores the relationship between eugenics, disability, and dehumanization, with a focus on forms of eugenics beyond Nazi eugenics.

As COVID-19 continues to spread, a variety of COVID-19 tracking apps have been introduced to help contain the pandemic. Deployment of this technology poses serious challenges of effectiveness, technological problems and risks to privacy and equity. The ethical use of CTAs depends heavily on the protection of voluntariness. Voluntary use of CTAs implies not only the absence of a legal obligation to employ the app but also the absence of more subtle forms of coercion such as enforced exclusion from certain (...) social and work activities. The protection of individual rights to voluntary use can be enhanced through an ethics by design approach in the development of CTAs that treat the introduction of CTAs for what it is: a complete novelty that is being tested for the first time in democracies. (shrink)

The Making of British Bioethics provides the first in-depth study of how philosophers, lawyers and other 'outsiders' came to play a major role in discussing and helping to regulate issues that used to be left to doctors and scientists. It details how British bioethics emerged thanks to a dynamic interplay between sociopolitical concerns and the aims of specific professional groups and individuals who helped create the demand for outside involvement and transformed themselves into influential 'ethics experts'. Highlighting this interplay helps (...) us appreciate how issues such as embryo research and assisted dying became high-profile 'bioethical' concerns in the late twentieth century, and why different groups now play a critical role in developing regulatory standards and leading public debates. The book draws on a wide range of original sources and will be of interest to historians of medicine and science, general historians and bioethicists. (shrink)

There is a strong interconnection between the social and environmental spheres. The efforts of monitoring and forecasting of disastrous events can illustrate benefits and threats of technicization and science. In ecophilosophy the forecasting of hazards is today extremely needed. It is not about creating theoretical unified structures or practical return to holistic harmony of a primordial man with nature. It is about, as Félix Guattari once held it, the complexity of the relationship between humans and their natural environment. Though the (...) desired maintenance of the conflict between industrial society and natural systems now seems impossible, we still can start moving towards it: theoretically, by developing eco-philosophical ideas, and practically, monitoring and forecasting catastrophes and disasters, to protect human life and health and, as eco-philosophers would say, keep land usable for human purposes. The topic of the earthquakes forecast today is more in demand than ever. (shrink)

This paper offers a contribution to ecophilosophy from the perspective of the scientific research of the environment. The problem considered in the paper deals with a specific issue of environmental risk, namely, the problem of radon ionizing radiation and the highest permissible security norms of it. This problem, now rarely discussed in ecological communities, is one of more important for humankind’s health and safe existence. The awareness of harmful and beneficial biological effects of various environmental factors is a basic step (...) towards ensuring the security of public health. The admissible norms of radon radiation are different in different countries. The article suggests possible causes of these differences and puts forward the thesis that today’s science alone is not a sufficient ground of resolving ecological problems. (shrink)

Recent developments around the sharing economy bring to the fore questions of governability and broader societal benefit—and subsequently the need to explore effective means of public governance, from nurturing, on the one hand, to restriction, on the other. As sharing is a predominately urban phenomenon in modern societies, cities around the globe have become both locus of action and central actor in the debates over the nature and organization of the sharing economy. However, cities vary substantially in the interpretation of (...) potential opportunities and challenges, as well as in their governance responses. Building on a qualitative comparative analysis of 16 leading global cities, our findings reveal four framings of the sharing economy: ‘societal endangerment,’ ‘societal enhancement,’ ‘market disruption,’ and ‘ecological transition.’ Such framings go hand in hand with patterned governance responses: although there is considerable heterogeneity in the combination of public governance strategies, we find specific configurations of framings and public governance strategies. Our work reflects the political and ethical debates on various economic, social, and moral issues related to the sharing economy, and contributes to a better understanding of the field-level institutional arrangements—a prerequisite for examining moral behavior of sharing economy organizations. (shrink)

Democracy depends on a vivid public sphere, where ideas disseminate into the public and can be discussed – and challenged - by everyone. Journalism has contributed significantly to this social mediation by reducing complexity, providing information on salient topics and (planned) political solutions. The digital transformation of the public sphere leads to new forms of media provision, distribution, and use. Journalism has struggled to adapt to the new conditions. Journalistic news values, relevant to democracy, are being replaced by ones relevant (...) to social media platforms’ attention seeking business model. We plead for a broad public debate about the ongoing platformization and about possible policies to ensure a media system that serves and strengthens democracy. (shrink)

Let us begin with the simple observation that applied mathematics can be very tough! It is a common occurrence that basic physical principle instructs us to construct some syntactically simple set of differential equations, but it then proves almost impossible to extract salient information from them. As Charles Peirce once remarked, you can’t get a set of such equations to divulge their secrets by simply tilting at them like Don Quixote. As a consequence, applied mathematicians are often forced to pursue (...) roundabout and shakily rationalized expedients if any useful progress is to be made. Often these provisional and quasi-empirical procedures within applied mathematics loom large in motivating the “anti-realist” or “anti-unificationist” conclusions of Nancy Cartwright and allied authors. (shrink)

In this paper I shall compare two models of concept formation, both inspired by basic convictions of philosophical empiricism. The first, the connectionist model, will be exemplified by Kohonen maps, and the second will be my own dynamic theory of concept formation. Both can be understood in probabilistic terms, both use a notion of convergence or stabilization in modelling how concepts are built up. Both admit destabilization of concepts and conceptual change. Both do not use a notion of representation in (...) some pregiven language, such as a language of thought or some logical language. Representation in a formal language only plays a role on the meta-level, namely within the theory about concept formation. (shrink)

How should physical entities be characterized? Physicalists, who have most to do with the notion, usually characterize the physical by reference to two components: 1. The physical entities are the entities treated by fundamental physics with the proviso that 2. Physical entities are not fundamentally mental (that is, do not individually possess or bestow mentality) Here I explore the extent to which the appeals to fundamental physics and to the NFM (“no fundamental mentality”) constraint are appropriate for characterizing the physical, (...) especially for purposes of formulating physicalism. Ultimately, I motivate and defend a version of an account incorporating both components: The physics-based NFM account: An entity existing at a world w is physical iff (i) it is treated, approximately accurately, by current or future (in the limit of inquiry, ideal) versions of fundamental physics at w, and (ii) it is not fundamentally mental (that is, does not individually either possess or bestow mentality). (shrink)

Essentialism is widely regarded as a mistaken view of biological kinds, such as species. After recounting why (sections 2-3), we provide a brief survey of the chief responses to the “death of essentialism” in the philosophy of biology (section 4). We then develop one of these responses, the claim that biological kinds are homeostatic property clusters (sections 5-6) illustrating this view with several novel examples (section 7). Although this view was first expressed 20 years ago, and has received recent discussion (...) and critique, it remains underdeveloped and is often misrepresented by its critics (section 8). (shrink)

National Book Award Finalist. How did humanity originate and why does a species like ours exist on this planet? Do we have a special place, even a destiny in the universe? Where are we going, and perhaps, the most difficult question of all, "Why?" In The Meaning of Human Existence, his most philosophical work to date, Pulitzer Prize–winning biologist Edward O. Wilson grapples with these and other existential questions, examining what makes human beings supremely different from all other species. (...) Searching for meaning in what Nietzsche once called "the rainbow colors" around the outer edges of knowledge and imagination, Wilson takes his readers on a journey, in the process bridging science and philosophy to create a twenty-first-century treatise on human existence—from our earliest inception to a provocative look at what the future of mankind portends. Continuing his groundbreaking examination of our "Anthropocene Epoch," which he began with The Social Conquest of Earth, described by the New York Times as "a sweeping account of the human rise to domination of the biosphere," here Wilson posits that we, as a species, now know enough about the universe and ourselves that we can begin to approach questions about our place in the cosmos and the meaning of intelligent life in a systematic, indeed, in a testable way. Once criticized for a purely mechanistic view of human life and an overreliance on genetic predetermination, Wilson presents in The Meaning of Human Existence his most expansive and advanced theories on the sovereignty of human life, recognizing that, even though the human and the spider evolved similarly, the poet's sonnet is wholly different from the spider's web. Whether attempting to explicate "The Riddle of the Human Species," "Free Will," or "Religion"; warning of "The Collapse of Biodiversity"; or even creating a plausible "Portrait of E.T.," Wilson does indeed believe that humanity holds a special position in the known universe. The human epoch that began in biological evolution and passed into pre-, then recorded, history is now more than ever before in our hands. Yet alarmed that we are about to abandon natural selection by redesigning biology and human nature as we wish them, Wilson soberly concludes that advances in science and technology bring us our greatest moral dilemma since God stayed the hand of Abraham. (shrink)

This paper offers an overview of "the species problem", arguing for a view of species as homeostatic property cluster kinds, positioning the resulting form of realism about species as an alternative to the claim that species are individuals and pluralistic views of species. It draws on taxonomic practice in the neurosciences, especially of neural crest cells and retinal ganglion cells, to motivate both the rejection of the species-as-individuals thesis and species pluralism.

Transformation of the sparrow and the butterfly -- Meeting the gods of poverty in a dream -- The greatest joys of the cicada and its cast-off shell -- The owl's understanding -- The centipede questions the snake -- The toad's way of the gods -- The mysterious technique of the cat -- Afterword by William Scott Wilson.

The epistemological problems of unification of two distinct theories are discussed. An approach related to the work of Soviet authors (Stepin, Podgoretzky and Smorodinsky) is used and developed. The notion of ‘crossbred objects’—theoretical objects with contradictory properties which are part of the domain of application of two independent theories—is introduced which helps to describe the dynamics of revolutionary theory change. The occurrence of the cross-contradiction of two theories is reconstructed and the reductionistic and the synthetic means of its elimination are (...) proposed. The results of the methodological analysis are applied to the paradox of equivalence. (shrink)

Martin Heidegger und Hans Jantzen gehören zu den wichtigsten Vertretern der Philosophie und Kunstgeschichte des 20. Jahrhunderts. Seit den 1920er bis Ende der 1960er Jahre kritisierten sie vorherrschende, naturwissenschaftlich geprägte Auffassungen des Raums und entwickelten einen neuartigen Begriff. Dieser sogenannte künstlerische Raum sei ein freies Zusammenspiel von materiellen und immateriellen Bestandteilen, das als solches erst in der Wahrnehmung real wird. Die Autorin arbeitet dieses Verständnis heraus und stellt es in einen geistes- und zeitgeschichtlichen Kontext. Neben der Bedeutung der Bestandteile und (...) der Grenze für die Gestalt und die Wirkung des Raums kommt der des Lichts sowie Jantzens Diaphanie-Begriff besondere Aufmerksamkeit zu. Für die erörterte Raumbeschaffenheit werden Anhaltspunkte in der gotischen Kathedrale und in Werken der Bronzezeit, Dorik, Ottonik und Moderne sowie von Kindern und Laien festgestellt. Im Anschluss an zeitgenössische Theorien ergeben sich Übereinstimmungen mit dem Konzept des geopolitischen Groß-raums und einer erdbezogenen Ästhetik. Vor dem Hintergrund des Kunst- und Sprachbegriffs der Epoche wird abschließend Heideggers und Jantzens Ansicht untersucht, alle Kunst sei sprachlich, sowie inwiefern sich diese Sprachlichkeit räumlich manifestiert. Die Zusammenführung von Jantzens Analyse ottonischer Wortbilder mit Heideggers Auslegung moderner Dichtung und Bildkunst zeigt, dass deren Raumbegriff unabhängig von politischen Bezügen bestehen kann. „Bei diesem Buch handelt es sich fraglos um eine kunsthistorisch und philosophisch bedeutsame Untersuchung.“. (shrink)

Gegenstand dieser politikwissenschaftlichen Arbeit ist weder die >Textur des Gewissens von Politikern, noch das sozialöffentliche Gewissen, also die Untersuchung von Wohlfahrts-sytemen. Es geht vielmehr um Konzeptionen des moralisch-individuellen Gewissens und der darin konturierten Beziehung zum politischen System. Zentrales Thema ist mithin die Frage nach dem Verhältnis von individueller Freiheit und politischer Ordnung. Dabei wird das semantische Feld im Kontext der Termini Gewissen, Moral und Ethik neu formuliert. Mittels einer Analyse der Gewissensdiskurse in der Frühmoderne sowie in der Spätmoderne läßt sich (...) die These entfalten, daß die Erkenntnis der neuartigen normativen Prob-lemstrukturen im technischen Zeitalter eine politologische Aufklärung erfordern, welche die zu-nehmend erkennbar werdenden Grenzen des Wissens in die Theoriebildung einbezieht. Die Poli-tik- und Sozialwissenschaften befinden sich gegenwärtig in einer Schwellenphase, in der die herkömmlichen normativen Erklärungsmuster, die in der Tradition des ethischen Humanismus verwurzelt sind, zu erodieren beginnen - doch werden die weitreichenden Konsequenzen des gegenwärtig sich vollziehenden sozio-technischen Umbruchs für die politische Ethik allenfalls halbherzig gezogen. Anstelle des populären Rufs nach einer Ethiksteuerung, die via wissenschaft-licher Begründungskonstruktionen und Regelwerken die politische Emanzipation der Individuen verbindlich anleiten soll, wird in diesem Buch für einen Perspektivenwechsel durch die Ver-schiebung der gewissensrelevanten Leitfragen votiert. Dabei erweist sich - kontraintuitiv -, daß dem Subjekt. (shrink)