AbstractDuring the Covid-19 pandemic, ethicists and researchers proposed human challenge studies as a way to speed development of a vaccine that could prevent disease and end the global public health crisis. The risks to healthy volunteers of being deliberately infected with a deadly and novel pathogen were not low, but the benefits could have been immense. This essay is a history of the three major efforts to set up a challenge model and run challenge studies in 2020 and 2021. The (...) pharmaceutical company Johnson and Johnson, the National Institutes of Health in the United States, and a private-public partnership of industry, university, and government partners in Britain all undertook preparations. The United Kingdom’s consortium began their Human Challenge Programme in March of 2021.Beyond documenting each effort, the essay puts these scientific and ethical debates in dialogue with the social, epidemiological, and institutional conditions of the pandemic as well as the commercial, intellectual, and political systems in which medical research and Covid-19 challenge studies operated. It shows how different institutions understood risk, benefit, and social value depending on their specific contexts. Ultimately the example of Covid-19 challenge studies highlights the constructedness of such assessments and reveals the utility of deconstructing them retrospectively so as to better understand the interplay of medical research and research ethics with larger social systems and historical contexts. (shrink)

Mabel Cooper and Gloria Ferris lived in St Lawrence's Hospital one of the large learning disability institutions which were built round the edges of London. In this paper, Mabel and Gloria share their memories of three nurses at St Lawrence's, supported by Jane Abraham and in this process reveal a number of ethical issues that remain relevant today.

The Coalition of Immokalee Workers (CIW) has successfully combated modern-day slavery by transforming the ways that over a dozen major brands, including Taco Bell, Subway, and Wal-Mart, manage their supply chains. The CIW’s efforts over more than 20 years have effectively stopped enslavement practices, including abuses such as wage theft and peonage indebtedness. We conducted a field ethnography, interviews, and archival analyses to understand this success. We find that the CIW employs a decentered, egalitarian, and ensemble approach to their multiplicities (...) of alliances by collectively “animating” themselves and their partners through ensemble leadership. This combination of alliances, along with worker-driven monitoring, brings life to the CIW motto “We are all leaders.” Translating this motto into daily practice is how the CIW virtually eradicates enslavement practices in corporate supply chains. (shrink)

In “A Tension in the Strong Program: The Relation between the Rational and the Social”, Shahram Shahryari (2021) advances the following thesis: In his Strong Program in the sociology of science, David Bloor blames traditional philosophy of science for adopting a dualist strategy in explaining scientific developments, as it employs rational explanation for successful science and social explanation for flawed science. Instead, according to Bloor, all scientific developments should be explained monistically, i.e. in terms of social causes. This is also (...) referred to as the Symmetry Principle, and it is a key tenet in the Strong Program. The author detects a tension here, as Bloor apparently asserts that traditional philosophy of science deploys two kinds of explanation, and simultaneously insists that there is only one kind, i.e. social explanation. (shrink)

Por un lado, el libro aborda la problemática educativa que enfrentan estudiantes mexicanos indocumentados en las universidades de los Estados Unidos. Por el otro lado, se aborda la atención específica (escolar, académica y administrativa) que la Universidad de Guadalajara (México), ofrece a los estudiantes migrantes retornados de los Estados Unidos.

_Migration and the Education of Young People 0_–_19_ investigates migration from a number of perspectives to consider the changing dynamics of society within different countries. Examining the data associated with global migration by focusing on case studies from a wide range of countries, it provides detailed and balanced coverage of this politically sensitive topic to explore the educational needs of migrant young people, the impact of large-scale migration to and from countries and the policy challenges that individual countries face when (...) ensuring adequate provision for migrant young people within their education systems. Chapters cover: The reasons why people might move Social and emotional learning in Britain: a tool to guard against cultural pollution? Migration into a global city: the economic and educational success of London Latvian people on the move and the impact on education People’s movement – Greece Return migration in Lithuania: incoming challenges for children’s education The United States, Latin America, immigration and education Tanzanian street children: victims, ordinary lives or extraordinary survivors? This book explores the changing social dynamics through an extensive range of case studies and will be an essential resource for students taking undergraduate and postgraduate courses in education, sociology and international relations. (shrink)

Volume 20, Issue 6, June 2020, Page 75-77.

Drawing on the pragmatic turn in contemporary social theory, we explore how corporate elites accused of corruption in the context of weak institutions engage in their justification works. Empirically, we focus on three high-profile corruption scandals that shook Ghana between 2010 and 2020 and inspired widespread public condemnation. Publicly accessible archival documents, such as court reporting, newspaper stories, press conferences, and the digital footprints of corporate elites implicated in the scandals provide data for our inquiry. Focussing on the juxtaposition of (...) ‘sayings’ and ‘doings’, the findings show justification as performative, and rooted in contextual pragmatism that acknowledges the plurality of logics situated between self-interest and folk-logic. Within this framework, the domestic and civic orders of worth emerge as most prominent, with the justification processes manifesting through _victimising, scapegoating,_ and _crusading_. Building on these insights, we develop a framework that highlights how the use of justifications serves as a critique of the inadequacies within climates of weak institutional frameworks consequently fostering an atmosphere conducive to framing unethical conducts as morally acceptable. (shrink)

The final published book by Nobel Prize-winning author and philosopher Henri Bergson (1859-1941), La pensée et le mouvant (translated here as The Creative Mind), is a masterly autobiography of his philosophical method. Through essays and lectures written between 1903 and 1923, Bergson retraces how and why he became a philosopher, and crafts a fascinating critique of philosophy itself. Until it leaves its false paths, he demonstrates, philosophy will remain only a wordy dialectic that surmounts false problems. With masterful skill and (...) intensity, Bergson shows that metaphysics and science must be rooted in experience for philosophy to become a genuine search for truth. And in the quest for unanswered questions, the spiritual dimension of human life and the importance of intuition must be emphasized. A source of inspiration for physicists as well as philosophers, Bergson's introduction to metaphysics reveals a philosophy that is always on the move, blending man's spiritual drive with his mastery of the material world. (shrink)

Cet article traite d’un mythe cosmogonique où un dragon mapuche, le Kai Kai Filu, appartenant à la Patagonie argentine et chilienne, est signalé comme le responsable du déluge, de la montée des eaux et de la formation des golfes, îles et autres accidents géographiques. Un suivi du mythe montre qu’avec les frontières dressées entre ces deux pays, les populations originaires se sont fragmentées ainsi que leurs récits millénaires. Le résultat est que l’Argentine présente un mythe segmenté, plus proche des mythes (...) occidentaux et le sud du Chili nous raconte une version plus ancienne, faisant basculer le sens de la figure du dragon et sa forme dans un glissement symbolique significatif. Ce mythe vit de manière permanente et apparaît dans de nombreuses narrations locales, narrations qui vont témoigner de la vitalité du mythe : il change et se renouvelle selon les mouvements de la terre et les tsunamis qui se succèdent dans cette région du Sud. Les versions s’enrichissent quand les changements des structures économiques bouleversent la vie des habitants et que de nouveaux éléments apparaissent dans les contes populaires, revigorisant le mythe originel. (shrink)

Presentación del Dossier: Feminismos y posthumanismo.

A prominent approach to scientific explanation and modeling claims that for a model to provide an explanation it must accurately represent at least some of the actual causes in the event's causal history. In this paper, I argue that many optimality explanations present a serious challenge to this causal approach. I contend that many optimality models provide highly idealized equilibrium explanations that do not accurately represent the causes of their target system. Furthermore, in many contexts, it is in virtue of (...) their independence of causes that optimality models are able to provide a better explanation than competing causal models. Consequently, our account of explanation and modeling must expand beyond the causal approach. (shrink)

Decisions about continuing or terminating a pregnancy touch on profound, individualized questions about bodily integrity, reproductive autonomy, deeply held values regarding one's capacity for parenthood, and, in the case of a high-risk pregnancy, the risks one is willing to take to have a baby. So far as possible, reproductive decisions are made between a patient, in some cases her partner, and her medical provider. However, this standard framework cannot be applied if the patient lacks decision-making capacity. In this essay, we (...) discuss one such case that came before our clinical ethics team. We describe the challenges of respecting a patient's reproductive preferences when the patient cannot share what those preferences are, and we argue that decisions regarding reproductive health care should not be treated with exceptionalism. Rather, they should proceed under the normal processes of surrogate decision-making, including the application of substituted judgment. This approach enables us to take the patient's values into account when considering the questions implicated in reproductive health care, just as we do for other kinds of health care decisions in which a patient's deeply held values are salient. (shrink)

We examine the impact of corporate culture on environmental performance using a sample of 7199 firm-year observations over the period of 2002–2018. We find that stronger corporate culture improves environmental performance, measured by the amount of toxic chemical release (TCR). Our result is both statistically and economically significant. We also show that cultural norms of innovation, quality and teamwork as well as a technology-oriented corporate culture have a greater impact on enhancing environmental performance. Further analyses show that managerial competence and (...) strong institutional ownership moderate the relationship between corporate culture and environmental performance. We introduce the decomposition of expected and unexpected components of TCR and document that firms with a strong corporate culture implement strategies to reduce the unexpected component of TCR in addition to the expected component of TCR. Finally, we document that strong corporate culture and environmental performance improve firms’ financial performance. Our results are robust to several sensitivity tests and procedures to mitigate endogeneity and self-selection problems. From a practical point of view, our findings suggest that a firm’s culture can determine its environmental sustainability and ethical practices. (shrink)

Many accounts of scientific modelling assume that models can be decomposed into the contributions made by their accurate and inaccurate parts. These accounts then argue that the inaccurate parts of the model can be justified by distorting only what is irrelevant. In this paper, I argue that this decompositional strategy requires three assumptions that are not typically met by our best scientific models. In response, I propose an alternative view in which idealized models are characterized as holistically distorted representations that (...) are justified by allowing for the application of various modelling techniques. (shrink)

Las confesiones de Tauber han recorrido varios continentes desde el año 1997 y aseguraría que han sido leídas por muchos médicos. Tienen características que las hacen muy atractivas para las personas que hemos elegido la medicina como parte de nuestra vida: historias clínicas y relatos de la práctica profesional. Y, además y sobre todo, el autor se empeña en diagnosticar y curar el cuerpo herido y el alma enferma de la Medicina, planteándose con pasión todas las posibilidades que ofrezcan esperanza. (...) Hay búsqueda de causas, de hipótesis explicativas, de referencias ilustradas y humanistas y del auxilio de los que más saben. Todo para llegar a un diagnóstico y a un plan terapéutico: alivio de los síntomas, posibilidades de curación o de regeneración saludable para favorecer el buen funcionamiento presente y futuro. Ya no será igual, pero no tiene porqué ser peor. El tratamiento y la rehabilitación serán duros y todavía son experimentales, pero están bien fundamentados. .. (shrink)

Volume 20, Issue 3, March 2020, Page 39-41.

Some patients who have been diagnosed as “dead by neurologic criteria” continue to exhibit certain brain functions, most commonly, neuroendocrine functions. This preservation of neurologic function after the diagnosis of “brain death” or “brainstem death” is an ongoing source of controversy and concern in the medical, bioethics, and legal literatures. Most obviously, if some brain function persists, then it is not the case that all functions of the entire brain have ceased and hence, declaring such a patient to be “dead” (...) would be a false positive, in any nation with so-called “whole brain death” laws. Furthermore, and perhaps more concerning, the preservation of any brain function necessarily entails the preservation of some amount of brain perfusion, thereby raising the concern as to whether additional areas of neural tissue may remain viable, including areas in the brainstem. These and other considerations cast significant doubt on the reliability of diagnosing either “brain death” or “brainstem death.”. (shrink)

In this paper, I first argue against various attempts to justify idealizations in scientific models that explain by showing that they are harmless and isolable distortions of irrelevant features. In response, I propose a view in which idealized models are characterized as providing holistically distorted representations of their target system. I then suggest an alternative way that idealized modeling can be justified by appealing to universality.

Intersectionality has attracted substantial scholarly attention in the 1990s. Rather than examining gender, race, class, and nation as distinctive social hierarchies, intersectionality examines how they mutually construct one another. I explore how the traditional family ideal functions as a privileged exemplar of intersectionality in the United States. Each of its six dimensions demonstrates specific connections between family as a gendered system of social organization, racial ideas and practices, and constructions of U.S. national identity.

El pueblo mapuche, pueblo originario del Sur de América --Chile--, posee un sistema de comunicación propio articulado a una visión mítico-simbólica y sacralizada del mundo, condición que implica una diversidad de códigos y lenguajes que operan integradamente para la comunicación entre las diferentes dimensiones y entidades que componen este cosmos. La irrupción de occidente ha incidido en la transformación de la práctica tradicional de este pueblo debido al proceso de dominación hegemónica que ha buscado desarticularlo, ante el cual el pueblo (...) mapuche, desde la segunda mitad del siglo XX, implementa diversas estrategias tendientes a recuperar su territorio y autonomía cultural. Este trabajo sostiene que una de las principales estrategias contrahegemónicas es la creación de un macrosistema de comunicación intercultural que responde a un proceso metacognitivo complejo sustentado en distintas fases y niveles de elaboración epistémica. Con el propósito de dar cuenta de este proceso este trabajo se centra en el estudio de uno de sus subsistemas: el artístico, desde el cual se describen y reflexionan los territorios y fronteras simbólicas que se generan respecto del sistema de comunicación occidental. The Mapuche people in southern Chile, South America, have a system of communication organized upon a sacred mythical symbolic view of the world, a condition that implies a diversity of codes and languages working altogether to communicate in the different dimensions and entities that integrate this cosmos. Irruption of the western world and its hegemonic dominance have influenced and transformed these people’s culture, trying to break it apart. Since the second half of the 20th century, Mapuche people have developed varied strategies to recover their land and cultural autonomy. The present paper holds that one of the main strategies against this hegemony is the creation of a macro system of intercultural communication, which derives from a complex metacognitive process supported by different phases and epistemic elaboration levels. This paper focuses on one of those systems: the artistic one, from which we describe the land areas and symbolic borders produced in relation to the western communication system. (shrink)

With the increasing professionalization of clinical ethics, some hospitals and health systems utilize both ethics committees and professional clinical ethicists to address their ethics needs. Drawing upon historical critiques of ethics committees and their own experiences, the authors argue that, in ethics programs with one or more professional clinical ethicists, ethics committees should be dissolved when they fail to meet minimum standards of effectiveness. The authors outline several criteria for assessing effectiveness, describe the benefits of a model that places primary (...) responsibility for ethics work with professional clinical ethicists—the PCE-primary model, and offer suggestions for alternative ethics program structures that empower healthcare professionals to contribute to ethics work in ways more tailored to their strengths and skills while minimizing the shortcomings of ethics committees. (shrink)

The authors present a case study involving truth telling responsibilities in the setting of nonepileptic seizures. Specifically, over the course of several suspected nonepileptic seizures, a patient’s seizures stopped after he received a saline flush meant to precede the administration of anti-seizure medication. The patient and his surrogate believed he had received the medication each time, and the team wondered whether they should disclose the truth. Some worried that disclosure would reinforce the suspected psychogenic behavior, exacerbating the patient’s condition. In (...) this way, the case study presents a twist on the traditional truth telling archetype. While most truth telling cases center on navigating cultural differences or worries about emotional harm, this case presented concerns about medical harm in the form of exacerbating the patient’s condition. The authors describe the complex patient-family-team dynamic that preceded this ethical dilemma, describe the case, analyze the ethical issue, and describe the outcome. (shrink)

Recently philosophers of science have begun to pay more attention to the use of highly idealized mathematical models in scientific theorizing. An important example of this kind of highly idealized modeling is the widespread use of optimality models within evolutionary biology. One way to understand the explanations provided by these models is as a censored causal explanation: an explanation that omits certain causal factors in order to focus on a modular subset of the causal processes that led to the explanandum. (...) In this paper, I first argue that the censored causal model approach fails to establish a permanent explanatory role for optimality models in biology and mischaracterizes the explanatory virtues of biological optimality modeling. In addition, I argue that many biological optimality explanations cannot be characterized as censored causal explanations. In response, I propose an alternative approach that analyzes optimality models’ reliance on synchronically representing a system’s constraints and tradeoffs as well as their employment of various kinds of idealization in order to provide equilibrium explanations. (shrink)

Catherine Elgin has recently argued that a nonfactive conception of understanding is required to accommodate the epistemic successes of science that make essential use of idealizations and models. In this paper, I argue that the fact that our best scientific models and theories are pervasively inaccurate representations can be made compatible with a more nuanced form of scientific realism that I call Understanding Realism. According to this view, science aims at (and often achieves) factive scientific understanding of natural phenomena. I (...) contend that this factive scientific understanding is provided by grasping a set of true modal information about the phenomenon of interest. Furthermore, contrary to Elgin’s view, I argue that the facticity of this kind of scientific understanding can be separated from the inaccuracy of the models and theories used to produce it. (shrink)

This paper analyzes two ways idealized biological models produce factive scientific understanding. I then argue that models can provide factive scientific understanding of a phenomenon without providing an accurate representation of the features of their real-world target system. My analysis of these cases also suggests that the debate over scientific realism needs to investigate the factive scientific understanding produced by scientists’ use of idealized models rather than the accuracy of scientific models themselves.