The starting point for the following reflections comes from Jacques Roger’s monumental work, Les sciences de la vie dans la pensée française du XVIIIe siècle. I hope my remarks may cast some light on a problem that has long remained obscure, and doubtless was to Buffon himself: the status of matter in general and the relation of brute to organic matter in particular.

I. L'organisation -- II. La génération -- III. La sensation.

Ce texte est la suite d'une réflexion présentée ici. Les rythmes du vivant Tel est l'aspect de l'ontologie propre au Rêve de d'Alembert et aux Principes philosophiques privilégié par beaucoup de spécialistes. Selon Amor Cherni, par exemple, Diderot serait « l'un des premiers modernes à avoir sérieusement secoué le principe d'identité puisque pour lui rien n'est fixe, rien ne reste ce qu'il est ; rien ne reste tel qu'il est. Les choses et les êtres, les sociétés et les (...) hommes apparaissent alors comme des (...) - Philosophie – Nouvel article. (shrink)

This article establishes the benefits of applying renewable energy and analyzes the main difficulties that have stood in the way of more widely successful renewable energy for rural areas in the developing world and discusses why outcomes from these technologies fall short. Although there is substantial recognition of technological, economic, institutional, and other supply-side barriers that have generally interfered with success, the household and other stake-holders have been left outside the scope of evaluation. This article first discusses the usefulness of (...) renewable energy for encouraging sustainability in rural, poor areas, analyzes barriers that have often interfered with the promotion and delivery of expected outputs of installed modern energy technology in remote communities, and finally presents findings from a survey on the actual performance state of the renewable energy technology and degree of satisfaction with it. (shrink)

Background: Direct–to–consumer genetic testing (DTCGT) offers risk estimates for a variety of complex diseases and conditions, yet little is known about its impact on actual users, including their decisions about sharing the information gleaned from testing. Ethical considerations include the impact of unsolicited genetic information with variable validity and clinical utility on relatives, and the possible burden to the health care system if revealed to physicians. Aims: The qualitative study explored primary care patients’ views, attitudes, and decision making considerations regarding (...) DTCGT. This article focuses on the disclosure decisions participants made regarding participation, testing, and results of DTCGT, a topic which arose as a secondary aim of the study. Methods: Through four longitudinal interviews (pre–test, results, 3 and 12 months post–test) we examined twenty primary care patients’ decisions, expressed intentions, and actions regarding disclosure to immediate and extended family, friends and coworkers, and physicians about participation in and results of DTCGT. Individual interviews were analyzed using qualitative content analysis and a summative approach to describe the global themes. Results: Most participants disclosed to some immediate family; less than half disclosed to extended family; approximately half talked to friends. Most participants stated they would or might disclose to physicians about DTCGT and a few did. Conceptual themes that emerged from the data analysis include ambivalence about disclosure, consistency between intention and actual disclosure behavior and decisions, and conditional information sharing. Conclusions: Participants’ intentional and actual disclosure patterns offer insight into how they view DTCGT, weigh results, and the potential impact of DTCGT. (shrink)

Robert Nozick argues that the problem of the meaning of life is caused by limitations, especially death. Consequently, attaining meaning in one’s life requires connecting to something larger than oneself. Since anything can be conceived of as meaningless from a wide enough perspective, meaning will ultimately depend on connecting to “the unlimited.” Although initially plausible, this theory of meaning is vulnerable to a number of objections. One is that “the unlimited” is an incoherent notion due to the necessity that it (...) include ideas that are contradictory to each other, and another is that the meaning of life ought to include internal goods, which Nozick ignores. I will defend Nozick’s theory against these two objections by bringing in elements of the thought of Aristotle and St. Thomas. (shrink)

Рассматривается понимание как специфически человеческий способ существования, как первичный, исходный опыт освоения человеком мира, в котором отсутствует субъект-объективная разделенность, лежащая в основе познавательного отношения. Для специалистов.

Building a meaningful model of biological regulatory network is usually done by specifying the components and their interactions, by guessing the values of parameters, by comparing the predicted behaviors to the observed ones, and by modifying in a trial-error process both architecture and parameters in order to reach an optimal fitness. We propose here a different approach to construct and analyze biological models avoiding the trial-error part, where structure and dynamics are represented as formal constraints. We apply the method to (...) Hopfield-like networks, a formalism often used in both neural and regulatory networks modeling. The aim is to characterize automatically the set of all models consistent with all the available knowledge. The available knowledge is formalized into formal constraints. The latter are compiled into Boolean formula in conjunctive normal form and then submitted to a Boolean satisfiability solver. This approach allows to formulate a wide range of queries, expressed in a high level language, and possibly integrating formalized intuitions. In order to explore its potential, we use it to find cycles for 3-nodes networks and to determine the flower morphogenesis regulatory network of Arabidopsis thaliana. Applications of this technique are numerous and concern the building of models from data as well as the design of biological networks possessing specified behaviors. (shrink)

By means of the averaging method of the first order, we introduce the maximum number of limit cycles which can be bifurcated from the periodic orbits of a Hamiltonian system. Besides, the perturbation has been used for a particular class of the polynomial differential systems.

Los principios de donde recibe el ente la existencia -- Naturaleza y sobre naturaleza -- Existencia de dios y Existencia de dios segun mi exposición -- Apéndices.

Amor Masovic, responsable de la commission de recherche des disparus en Bosnie-Herzégovine et ancien responsable de la commission pour l’échange des prisonniers pendant la guerre de 1992-1995, nous présente ensuite un tableau accablant des disparitions dans les guerres récentes en ex-Yougoslavie, et des pratiques pour faire en sorte que ceux-ci ne soient ni retrouvés ni, encore moins, identifiés (d’où des fosses communes de deux types : « primaires » – où les corps furent enterrés initialement – et « secondaires (...) » – où ces mêmes corps furent ré-enterrés, souvent démembrés, après avoir été déterrés pour être dispersés et moins aisés à repérer). 28 000 des 40 000 disparus ex-Yougoslaves relèvent du conflit en Bosnie et sont à 95 % des civils protégés par les conventions de Genève. Sur les 280 charniers identifiés la plupart se trouvaient à l’arrière et non sur le front et les disparitions sont datables à des périodes de non-combat. Le but de la commission est donc d’abord de retrouver et identifier les morts pour « faire savoir » et permettre le deuil (puisque la barbarisation qui a été exercée est double : contre les victimes et contre leurs familles qui ne peuvent « vivre » tant qu’elles n’ont pas de certitude). En outre, faute de disposition légale et d’une absence de droit spécifique des disparus personne ne peut être incriminé pour une disparition devant le TPIY où les « disparus » ne sont donc pas représentés. Amor Masovic tire quatre conclusions de son exposé : 1) la barbarie exprimée aujourd’hui est pour partie un résultat des manques de la justice à l’égard des crimes de guerre de la seconde guerre mondiale ; 2) la guerre contre les civils augmente en même temps qu’augmentent les dispositions internationales contre ces exactions qui restent donc purement formelles ; 3) en Bosnie, la barbarisation s’est exercée sur les corps des victimes de façon redoublée puisque l’anéantissement des preuves du crime fait que la mort n’est pas une vraie fin. D’où une forme particulière de barbarisation d’après-guerre ; 4) seul élément plus « positif » : en Bosnie des échanges de prisonniers eurent lieu pendant la guerre sans attendre la fin du conflit ce qui est rarissime et va au-delà des exigences posées par les conventions de Genève en matière de libération des prisonniers. (shrink)

Contrasting the conflicting positions of Fink and Žižek, this article opens and closes with the question: is feminine jouissance ineffable? It solves the mystery of why Lacan associates the Other jouissance with women and presents an account of phallic and the Other jouissance informed by the work of Breuer and Freud. It argues that the satisfactions of Lacan’s feminine subject bear striking affinity to those of the hysteric, while phallic jouissance affords the same sort of enjoyment as that of Freud’s (...) obsessional neurotic. And, while “real” experiences make one lose one-self and may not be represented by one who was absent, this is not to say that we cannot shed light on characteristically feminine pleasure/pains. (shrink)

The inclusion of animals in research studies involves a great responsibility to ensure animal welfare within the relevant ethical and legal frameworks. This study aimed to review compliance with the ARRIVE Essential 10 requirements and the ethical oversight of animal behaviour and welfare studies in farm animals. Three journals and a total of 133 articles were reviewed for compliance with the ARRIVE Essential 10 items and criteria. Each article obtained a final score according to whether or not each criterion was (...) met within each item. Likewise, ethical declaration in each article was recorded. Chi-square test and linear models were built to assess associations between the ethical statement presentation and the final ARRIVE Essential 10 score with the country, the species, and the journal. We found that 15% of the articles did not present an ethical statement. The journal with the highest impact factor and the countries of the Global South presented an ethical statement more frequently. Regarding the Essential 10, the item with the lowest agreement score was ‘Blinding’ and the one with the highest agreement was ‘Outcome Measures’. Also, significant differences were found between journals in terms of the Essential 10 score. Essential 10 provides relevant information that allows reviewers and readers to identify possible welfare risks and the validity of the results in animal welfare science publications. (shrink)

We use a lab experiment to examine whether and how leaders influence workers’ (un)ethical behavior through financial reporting choices. We randomly assign the role of leaders or workers to subjects, who can choose to report an outcome via automatic or self-reporting. Self-reporting allows for profitable and undetectable earnings manipulation. We vary the leaders’ ability to choose the reporting method and to punish workers. We show that workers are more likely to choose automatic reporting when their leader voluntarily does so and (...) can assign punishment. Even workers who choose self-reporting tend to cheat less when their leader chooses automatic reporting. Nonetheless, most leaders do not opt for automatic reporting in the first place: they often choose self-reporting and punish workers who rather choose automatic reporting. Collectively, our results reveal a dual effect of leadership on ethical behaviors in organizations: workers behave more ethically if their leader makes ethical choices, but often leaders do not make ethical choices in the first place. Hence, leading by example can backfire. (shrink)

Nada propone una interpretación de las diferentes conciencias (arcaica, mágica, mítica, mental e integral) que han ocupado los distintos eones que ha atravesado nuestra especie (urobórico, tifónico, matriarcal, patriarcal y fratriarcal), partiendo de que en todas ellas se ensayan diversos tratos con la nada o lo indeterminado. Se sugiere que, en cada eón, la respectiva conciencia pasa por una fase de ignorancia negativa (no sabe que no sabe), otra de ignorancia positiva (sabe que no sabe), un momento de impasse en (...) el que el decaimiento de una conciencia se cruza con la emergencia de otra, resultando de tal cruce un conocimiento inconsciente (no sabe que sabe), y un momento final de conciencia plena o sabiduría (sabe que sabe) desde el que se precipitan, de nuevo, pero en otro eón y sobre otra conciencia, nuevas ignorancias. (shrink)

Ezzence is the first smartphone-controlled olfactometer designed for both day and night conditions. We discuss the design and technical implementation of Ezzence and report on a study to evaluate the feasibility of using the device in home-based sleep environments. The study results show that participants were satisfied with the device and found it easy to use. Furthermore, participants reported a significant improvement in sleep quality when using the device with scent in comparison to the control condition, as well as better (...) mood the following morning and shorter time to sleep onset. The device is integrated with a wearable EEG and real-time sleep staging algorithm to release scent during specific sleep stages, which is important for certain use cases. Ezzence can be used for several applications, including those that require scent triggered day and night. They include targeted memory reactivation, longitudinal health treatments, therapy, and mental or physical exercises. Finally, this article proposes an interaction framework to understand relationships between scents and environments based on proxemic dimensions and passive or active interactions during sleep. (shrink)

This article introduces some soft computing methods generally used for data analysis and flow pattern detection in fluid dynamics. These techniques decompose the original flow field as an expansion of modes, which can be either orthogonal in time, or in space or in time and space, or they can simply be selected using some sophisticated statistical techniques. The performance of these methods is tested in the turbulent wake of a wall-mounted square cylinder. This highly complex flow is suitable to show (...) the ability of the aforementioned methods to reduce the degrees of freedom of the original data by only retaining the large scales in the flow. The main result is a reduced-order model of the original flow case, based on a low number of modes. A deep discussion is carried out about how to choose the most computationally efficient method to obtain suitable reduced-order models of the flow. The techniques introduced in this article are data-driven methods that could be applied to model any type of non-linear dynamical system, including numerical and experimental databases. (shrink)

ZUSAMMENFASSUNGDie renommierte Religionsphilosophin Eleonore Stump bezieht seit über zwei Jahrzehnten in zahlreichen Publikationen zur Theodizeeproblematik Stellung. In der vorliegenden Untersuchung werden Stumps Überlegungen zum problem of evil systematisiert und kritisch gewürdigt. Dabei zeigt sich, dass die zentrale Annahme, auf der Stumps Theodizee beruht, die Pädagogisierung des Leids im Rahmen einer free will defence, über die Jahre hinweg keine substantielle Modifikation erfahren hat.SUMMARYSince more than two decades well-known philosopher of religion Eleonore Stump has discussed in numerous publications the problem of evil. (...) This paper aims at systematizing and evaluating Stump's considerations on this topic. The paper shows that Stump's crucial assumption of interpreting evil from a pedagogic point of view within a free will defence has not changed substantially over the years. (shrink)