The purpose of this article is to present the results of a contrastive study of the ideas of male beauty among Russians and Chinese. These ideas are studied culturologically, through the restoration of the relevant fragments of national pictures of the world. For this purpose, both linguistic and comparative-historical methods are used. Russian concepts of beauty are analyzed in the corresponding concepts in the Russian language, etymology and modern meanings, Russian epics, the reign of Peter the Great, (...) the XVIII - XIX centuries, the period of the Great October Socialist Revolution, the Stalinist period and the period of late socialism, modern ideas. To analyze the Chinese view of the subject under study, the corresponding hieroglyphs, lexical combinations, idioms, philosophical and aesthetic sources, and modern realities are analyzed. Such a multidimensional consideration of beauty in the Russian and Chinese pictures of the world caused the novelty of the study. Comparisons of Russian and Chinese are the main conclusion of the work: ideas about beauty are not just different, they are opposite. It is important to note that the image of the hero in Russian culture is a symbol of male beauty, and in Chinese, on the contrary, it is a symbol of a rude and unaesthetic person. The main oppositions are male/female, West/The East, rational/emotional — are characteristic of the Russian picture of the world, but they are not completely manifested in the Chinese ideas about beauty. The Chinese do not oppose, but combine what looks like an opposition in our culture. (shrink)

Putting classical art to the side for the moment, the naked and near-naked female body became an object of mainstream consumption first in Playboy and its imitators, then in movies, and only then in fashion photographs. With the male body, the trajectory has been different. Fashion has taken the lead, the movies have followed. Hollywood may have been a chest-fest in the fifties, but it was male clothing designers [e.g., Calvin Klein] who went south and violated the really (...) powerful taboos--not just against the explicit depiction of penises and male bottoms but against the admission of all sorts of forbidden "feminine" qualities into mainstream conceptions of manliness. . . . Images of masculinity that will do double (or triple or quadruple) duty with a variety of consumers, straight and gay, male and female, are not difficult to create in a culture like ours, in which the muscular, male body has a long and glorious aesthetic history. (shrink)

The paper discusses some retellings of the “Sleeping Beauty” tale type ranging from the 14th to the 21st century: a chivalric romance, literary fairy tales, and films, both animated and live-action. The analysis focuses on the portrayals of the male rescuer figure. His heroization and idealization seem to be a relatively new addition to the “Sleeping Beauty” myth and constitute a strategy that allows to mitigate the savior-aggressor ambivalence of the character and the violence implicit in the (...) tale. (shrink)

Beauty has captured human interest since before Plato, but how, why, and to whom does beauty matter in today's world? Whose standard of beauty motivates African Americans to straighten their hair? What inspires beauty queens to measure up as flawless objects for the male gaze? Why does a French performance artist use cosmetic surgery to remake her face into a composite of the master painters' version of beauty? How does beauty culture perceive the (...) disabled body? Is the constant effort to remain young and thin, often at considerable economic and emotional expense, ethically justifiable? Provocative essays by an international group of scholars discuss beauty in aesthetics, the arts, the tools of fashion, the materials of decoration, and the big business of beautification—beauty matters—to reveal the ways gender, race, and sexual orientation have informed the concept of beauty and driven us to become more beautiful. Here, Kant rubs shoulders with Calvin Klein. Beauty Matters draws from visual art, dance, cultural history, and literary and feminist theory to explore the values and politics of beauty. Various philosophical perspectives on ethics and aesthetics emerge from this penetrating book to determine and reveal that beauty is never disinterested. Foreward by Eleanor Heartney; "Introduction" by Peg Brand [Weiser] included here. Authors include Marcia M. Eaton, Noel Carroll, Paul C. Taylor, Arthur C. Danto, Kathleen M. Higgins, Susan Bordo, Dawn Perlmutter, Eva Kit Wah Man, Anita Silvers, Hilary Robinson, Kaori Chino, Sally Banes, and Peg Brand's essay "Bound to Beauty: An Interview with Orlan." (available on PhilPapers). (shrink)

The pioneering work of Johann Winckelmann (1717-1768) identified a homoerotic appreciation of male beauty in classical Greek sculpture, a fascination that had endured in Western art since the Greeks. Yet after Winckelmann, the value (even the possibility) of art's queer beauty was often denied. Several theorists, notably the philosopher Immanuel Kant, broke sexual attraction and aesthetic appreciation into separate or dueling domains. In turn, sexual desire and aesthetic pleasure had to be profoundly rethought by later writers. Whitney (...) Davis follows how such innovative thinkers as John Addington Symonds, Michel Foucault, and Richard Wollheim rejoined these two domains, reclaiming earlier insights about the mutual implication of sexuality and aesthetics. Addressing texts by Arthur Schopenhauer, Charles Darwin, Oscar Wilde, Vernon Lee, and Sigmund Freud, among many others, Davis criticizes modern approaches, such as Kantian idealism, Darwinism, psychoanalysis, and analytic aesthetics, for either reducing aesthetics to a question of sexuality or for removing sexuality from the aesthetic field altogether. Despite these schematic reductions, sexuality always returns to aesthetics, and aesthetic considerations always recur in sexuality. Davis particularly emphasizes the way in which philosophies of art since the late eighteenth century have responded to nonstandard sexuality, especially homoeroticism, and how theories of nonstandard sexuality have drawn on aesthetics in significant ways. Many imaginative and penetrating critics have wrestled productively, though often inconclusively and "against themselves," with the aesthetic making of sexual life and new forms of art made from reconstituted sexualities. Through a critique that confronts history, philosophy, science, psychology, and dominant theories of art and sexuality, Davis challenges privileged types of sexual and aesthetic creation imagined in modern culture-and assumed today. (shrink)

Classical Greece is famous for its athletic art, particularly the image of the nude male athlete. But how did the Greeks understand athletic beauty? Plato, Aristotle, Xenophon, and others discuss athletes’ beauty, while the educational ideal of kalokagathia conceptually connects athletic beauty with the good. More questions need to be answered, however, if we are to understand ancient athletic beauty. We need to ask ourselves what the Greeks appreciated when they looked at athletic bodies. What (...) did those qualities mean to them? In what way was it erotic? How did it differ for females and males? In this paper I argue that the beautiful athletic body is framed in ancient Greek thought, not just as an aesthetically pleasing image, but as an ideal expression of a certain kind of soul. (shrink)

Recent feminist theory has attempted to bring considerations of women’s agency into analyses of the meaning and consequence of beauty norms in women’s lives. This article argues that these works have often been limited by their use of individualist frameworks or by their neglect of considerations of race and class. In this article I draw upon examples of African-American utilization of beauty discourse and practices in collective efforts to resist racism. I argue that there is no singular (...) class='Hi'>beauty standard enforced by a unified male gaze. Instead, we should conceive of fields in which differently located individuals and groups invest in and promote particular ways of seeing beauty, producing both penalties and pleasures in women’s lives. (shrink)

In this chapterI discuss beauty and youth in Balinese dance, with special reference to Legong. Legong is the "classic" Balinese dance genre for females and is represented by Balinese to the world as the quintessence of grace, charm, and beauty in their performing arts. . . . Apparently, the notion of beauty that is invoked here is not straightforwardly equivalent to the heterosexual male norms for female sexual attractiveness, which may favor younger women but don't require (...) them to be under twenty. What then is the connection between beauty and youth in Balinese legong? (shrink)

The phenomenon of apparently greater emphasis on human female physical attractiveness has spawned an array of explanatory responses, but the great majority can be broadly categorized as either evolutionary or social constructivist in nature. Both perspectives generate distinct and testable predictions. If, as Naomi Wolf (The beauty myth: How images of female beauty are used against women. New York: William Morrow, [originally published in 1991], 2002) and others have argued, greater emphasis on female attractiveness is part of a (...) predominantly Western “beauty myth,” then an analysis of a culturally diverse sample should reveal marked fluctuation in gendered attractiveness emphasis: there should be significant numbers of cultures in which male and female attractiveness are equally emphasized, and cultures in which male attractiveness receives more emphasis. On the other hand, an evolutionary perspective suggests that disproportionate emphasis on female attractiveness will be a universal or near-universal phenomenon. To test these hypotheses, we tallied references to male versus female attractiveness in 90 collections of traditional folktales from 13 diverse cultural areas. The results are consistent with the evolutionary predictions and inconsistent with the constructivist predictions. Across culture areas information on physical attractiveness was much more likely to be conveyed for female characters. Together with other recent studies, these results suggest that the main elements of the beauty myth are not myths: there are large areas of overlap in the attractiveness judgments of diverse populations, and cross-cultural emphasis on physical attractiveness appears to fall principally upon women. (shrink)

Instances of nudity in Westworld can be put into three categories: Nudity as a beautiful art form, nudity as a sign of (male) dominance, and nudity as a sign of humanity or more to the point, nudity as a sign of becoming human. All the hosts presented as nudes in Westworld are idealized. The hosts are always more idealized in their form than either the human guests or the human directors of the park. Kenneth Clark makes a key distinction (...) between being naked, “being without clothes”, and the nude as a form of art. He imagines that the idealized beauty of the nude is analogous to the architecture of a building: It is a “balance between an ideal scheme and functional necessities”. The idealization of the human body and the createdness of the hosts come together in the main human theme of both the park's creators and its visitors: Control. (shrink)

The paper aims at connecting the concepts of beauty and possession, traditionally coupled with the male gaze, with eros as felt by women, by homosexuals, and by those who do not identify with a defined gender. First, I will outline the concepts of beauty and possession according to “male thinking”, well formulated by Freud, Plato, Levinas, and Sartre. I will show that, in Western tradition, beauty is seen from a masculine perspective, as a set of (...) charms arousing the subject and stimulating his will to possess. The erotic relationship is consequently considered in a dualistic way: the subject is masculine and active, and desires his “object”, who can be either a man or a woman. However, the mentioned authors also highlight a crucial point: desire is doomed to be unfulfilled, because the transcendence of the other person is ungraspable. I will argue that, despite the latter point, such authors bring forward a reductionist view of eros and relationships between genders. I will suggest a solution to this reductionism, taking inspiration from the concepts of gender performativity, theorized by Butler, and queer orientation, developed by Ahmed. I will also propose to rely on Merleau-Ponty’s idea of the flesh, especially as it concerns its features of reversibility and divergence, in order to give account of every gender identity, including non-binary ones. The concepts of beauty and possession, together with the impossibility to grasp the transcendence of the other person, will not be rejected, but reconfigured through a different way of conceiving subjectivity. (shrink)

Medieval literature often used stock descriptions of beautiful women following a well-established rhetorical canon which included expressions such as "golden hair," "sparkling eyes," or "skin whiter than snow." But were these terms mere rhetorical conventions derived from Latin poetry, as generally accepted by medieval scholars? And what happens if we examine these descriptions at the "literal" level of interpretation? This survey of works in the languages of medieval Iberia shows that the medieval rhetorical portrait synthesized a widely shared ideal of (...) female beauty which coincides with today's male perceptions of female attractiveness, and is consistent with evolved psychological preferences. (shrink)

Facelifts, tummy tucks and breast enlargements are no longer the privilege of the rich and the famous. Any woman can have all these and many more cosmetic surgical treatments, and an increasing number of women do. Are they having cosmetic surgery because they are duped by a male-dominated beauty system, or do they genuinely choose these operations themselves? Feminists give diametrically opposed answers to this question. At the heart of the controversy, or so I claim in this article, (...) lies a conceptual problem about free choice; therefore, the only thing that can settle it is a conceptual analysis of “freedom”. After having briefly outlined the views of both sides of the debate, I offer such an analysis. (shrink)

This essay argues that feminist theory has focused, in the main and for too long, on theories of the body, in a legitimate reaction to a Western masculine coupling of beauty with a female or idealized maternal body and the sublime with male creativity. In consequence, there are few productive feminist accounts of female or maternal beauty. However, Virginia Woolf’s writings about beauty, mothers and the body, if read through the lens of post-Lacanian theory - particularly (...) the work of Luce Irigaray and Bracha Lichtenberg Ettinger - do offer a moving and positive feminist account of women and beauty. The essay analyses Woolf’s ideas about beauty in general, before focusing on To the Lighthouse and The Voyage Out in relation to the writings of Woolf’s mother Julia Stephen. (shrink)

The article attempts to describe adonization, a specific tactic for exerting influence which employs physical attraction, as well as its determinants. The article presents a proprietary model of determinants and motivational mechanisms which constitute the basis of the attitude toward adonization. A cycle of 3 studies on individual determinants for the attitude toward adonization was described. Results of study 1 confirmed that male gender, psychological masculinity, narcissism, Machiavellianism and high self-monitoring were correlates of a positive attitude toward adonization. Study (...) 2 showed that extraversion was the predictor of a positive attitude toward adonization of men and women and that agreeableness was the predictor of a less positive attitude of women. In Study 3 it was established that there were no differences in the attitude toward adonization in young and middle-aged men. Comparison among young and middle-aged women proved that younger women had a more positive attitude toward adonization in the cognitive and in the affective components than older women. (shrink)

Gathered here are 127 beautiful and provocative duotone photographs that reflect the wide-ranging history of male homoeroticism as revealed by the camera - amply suggesting spiritual, physical, and intellectual exchange between men.

Sex is probably the best example of stable biological variation within the human species. Scientists have tried to account for the origin of sex differences in biological terms using evolutionary theory. Although Charles Darwin derived his theories of natural and sexual selection with no consideration for sex, he assumed that the differences he observed in male and female human and animal behavior were variations related to biology. This chapter examines the link between sex and evolution by reflecting on the (...) various resonances between cultural and social norms one the one hand, and biological theory on the other. It first considers scientific explanations of women's nature, or womanhood as a subject of science, before turning to research on female choice and the animal/woman divide in the early twentieth century. The chapter also discusses the use of human and animal models of “natural” sexual behavior after World War II, sexual selection and biological determinism in the 1970s, and efforts to bridge the gap between feminism and evolutionary theory. (shrink)

This article considers the role of beauty in Costa Rican sex work. In the context of sex tourism, beauty operates as affective labour performed by sex workers, labour that is mediated by deeply contradictory understandings of race and nation. Theorising beauty as a form of affective labour means thinking about beauty as value, as something that circulates, can be exchanged and is ultimately relational. While Costa Rica's national mythology has long focused on claims to white origins, (...) sex tourists identify local women's ‘exoticism’ and non-whiteness as particularly appealing. Commercial sex does not simply depend on an imperial male gaze, but rather requires us to consider how particular national mythologies about race are linked to ideals of attractiveness in complex ways. I also explore how women experience and manage their sexual attractiveness to foreign tourists in their daily lives and work. (shrink)

Sociobiology has ignored the results of psychology, which is the discipline between biology and society. Campbell's target article fills some of the gaps beautifully, but the fact that women's direct and physical aggression has increased during the past 20 years, undermines Campbell's evolutionary explanation of female aggression. The two classical types of theoretical explanations of aggression are that (1) aggression is a drive and (2) aggression is instrumental behavior. Expressive aggression, assumed to be typical of women, is no more drive (...) aggression than is men's aggression. (shrink)

We trained chickens to react to an average human female face but not to an average male face (or vice versa). In a subsequent test, the animals showed preferences for faces consistent with human sexual preferences (obtained from university students). This suggests that human preferences arise from general properties of nervous systems, rather than from face-specific adaptations. We discuss this result in the light of current debate on the meaning of sexual signals and suggest further tests of existing hypotheses (...) about the origin of sexual preferences. (shrink)

Feminist explorations of the sublime and the beautiful have developed in markedly different directions. This is not surprising given the different histories of the two terms. Whereas the nature of the beautiful had been of key importance to Plato, Aristotle, and other ancient Greek and Roman philosophers, it was only during the Englightenment period that a strong contrast was established between the beautiful and the sublime. But this was also the time when there was a decisive shift away from regarding (...) the well-honed male body as best exemplifying the ideal of the beautiful, and beauty itself was domesticated and downgraded. As Mary Wollstonecraft registered in A Vindication of the Rights of Woman (Wollstonecraft 1996 [1792])--one of the earliest European feminist texts--to associate women with the duties of being beautiful in this newly demoted mode was, in effect, to give them the status of subordinate beings. Instead, Wollstonecraft aspired to the newly emergent category of the sublime, which was all too frequently being denied to ideally "feminine" women. (shrink)

The term “contemplation” has played a significant role in the history of Christian spirituality. Regardless of the tradition, whether Roman Catholic, Orthodox, or Protestant, contemplation has been valued. Recently, however, some Evangelicals have raised various concerns about contemplation, including its Roman Catholic origin, the tendency to devalue Jesus Christ and his atonement, the marginalization of Scripture, and the assertion that a person who seeks to grow in the contemplative life will no longer be active to witness to the gospel in (...) the world. This article while recognizing the potential for possible theological distortions argues that there is a biblical and theologically accurate manifestation of contemplation. In particular, this essay seeks to examine the presence of contemplation within the Evangelical church. To that end, the writings of four Americans representative of the beginning of eighteenth-century Evangelicalism are examined to discern whether they display a biblical and orthodox expression of contemplation. In all cases, whether male or female, Calvinist or Wesleyan, this quartet of spiritual leaders reveal and challenge contemporary Christians of all traditions to be more intentional about cultivating a loving and grateful gazing on God and desire to delight in and enjoy God more fully. (shrink)

Consumers’ actual knowledge about modern food production is limited, and their judgment is often guided by assumptions or associations that are not necessarily in line with reality. Consumers’ rather unrealistic idea of livestock farming is driven by beautiful and romanticized pictures in advertising. If confronted with the reality of modern livestock farming, consumers’ responses are mainly negative. So far, dairy farming still has a more positive image and thus is less affected by public criticism. However, if made public, some of (...) the current production practices in dairy farming have the potential to reduce consumer acceptance which in turn can have a tremendous effect on farmers. A particularly urgent topic is the handling of male dairy calves. Such calves are often treated as surplus animals due to their low genetic merits for meat, with the risk of resulting in the deprivation of animal welfare. To maintain consumer acceptance of dairy products and find socially accepted alternatives for the handling of male calves, insights into consumer perception of current and future production practices in dairy farming are needed. Thus, the aim of this study is to analyze how consumers evaluate the current situation of male dairy calves and alternatives in male calf management. A quantitative online survey, representative for the German population in terms of gender, age, education, region, and income, was carried out with 1 194 participants in February 2022. Overall, 60% of participants were not aware of the fact that male dairy calves are less appropriate for fattening purposes. Respondents saw a clear need for alternative methods for handling male calves from dairy production. More, our results show that the use of sexed semen encounters consumer resistance, while other alternatives that were evaluated as more natural were more accepted. A cluster analysis identified 3 distinct consumer segments labelled “sexed semen opponents” (31.6%), “undecided” (30.4%), and “proponents of all alternatives” (38.0%) that differed in their acceptance of alternative handling practices of male dairy calves. The results emphasize the gap between consumers’ expectations and reality on farms and the importance of considering consumer preferences when developing future pathways for dairy farming. (shrink)

Gellner relied extensively on the work of Ibn Khaldun to understand both the dynamics of social order in North Africa and Islam’s alleged resistance to secularization. However, what the two scholars also shared is their focus on the social origins and functions of group solidarity. For Ibn Khaldun the concept of asabiyyah was central in understanding the strength of long-term group loyalties. In his view, asabiyyah was a fundamental and elementary cohesive bond of human societies which originated in nomadic tribal (...) structures and retained significance in the early formation of complex states and empires. For Gellner, the shape and character of group solidarity is heavily dependent on the economic foundations of a particular social order: foragers require small group bonds for mere survival, the agrarian universe stratifies solidarity and utilizes cultural bonds to differentiate between the ruling aristocrats and the plough-tied serfs, whereas the industrial world generates solidarity from incessant economic growth and state-induced, cross-class, national identifications. Thus, for Gellner, solidarity remains the central force that keeps social orders together. This paper provides a critical analysis of the Khaldunian and Gellnerian models of group solidarity and offers an alternative interpretation that places the social impact of micro-solidarity in the long-term development of ideological and coercive forms of social organization. (shrink)

Ernest Gellner was a unique scholar whose work covered areas as diverse as social anthropology, analytical philosophy, the sociology of the Islamic world, nationalism, psychoanalysis, East European transformations and kinship structures. Despite this diversity, there is an exceptional degree of unity and coherence in Gellner's work with his distinctly modernist, rationalist and liberal world-view evident in everything he wrote. His central problematic remains constant: understanding how the modern world came into being and to what extent it is unique relative to (...) all other social forms. Ten years after his death, this book brings together leading social theorists to evaluate the significance of Gellner's legacy and to re-examine his central concerns. It corrects many misunderstandings and critically engages with Gellner's legacy to provide a cutting edge contribution to understanding our contemporary post-9/11, global, late modern, social condition. (shrink)

T.S. Kuhn sostiene que el desarrollo de la actividad científica se debe, precisamente, a los ciclos de continuidad y ruptura que han caracterizado la alternancia de esta actividad, denotando con ello el contraste existente entre los períodos de ciencia normal y las etapas revolucionarias marcad..

ObjectivesThis pilot study sought to develop and evaluate a novel online group-based intervention to help breast cancer survivors make healthy lifestyle changes intended to yield not only beneficial physical outcomes but also greater behavioral, and psychosocial well-being.MethodsAn exploratory single-arm, mixed-method triangulation design was employed to evaluate the feasibility and preliminary effectiveness of the HLM-ABC intervention for overweight BCSs. Fourteen women participated in the 10-week intervention and completed quantitative measures of the above-mentioned outcomes at baseline, post-treatment, 6-month, and 12-month follow-up time (...) points. Qualitative data were obtained post-treatment via semi-structured interviews and a treatment satisfaction questionnaire.ResultsParticipants lost an average of 2.83% of their baseline weight by 1-year follow-up, equal to a small effect size. Despite achieving only modest weight loss, participants achieved meaningful gains in the form of increased physical activity, discovery of gratifying movement, more intuitive eating habits, greater bodily and emotional awareness, and positive shifts in beliefs about being able to make healthy choices regarding food and physical activity. Furthermore, they demonstrated a slight improvement in body image and described feeling more self-compassionate, empowered, and acknowledging of variables beyond control that can present barriers to change.ConclusionAfter completing a 10-week online program, participants achieved meaningful and lasting changes on a number of healthful indicators, even when this did not correspond with a significant reduction in weight. Findings highlight the complex, multifaceted nature of “health” and lend support for promotion of healthier lifestyle following cancer treatment that encompasses not only physical weight, but also behavior, psychosocial well-being, and circumstances such as life-preserving hormonal treatments. (shrink)

This paper presents the story of an isiXhosa traditional healer, Nomzi Hlathi, as told to the first author. Nomzi was asked about how she came to be an igqirha and the narrative focuses on those aspects of her life story that she understood as relevant to that developmental process. The material was obtained from a series of semi-structured interviews with Nomzi, with some collateral from her cousin, and synthesised into a chronological narrative presented in Nomzi’s own words. The aim of (...) the study was to examine her account of her unfolding experience within three hermeneutic frames. The first is the isiXhosa traditional account of what it is to become an igqirha, a process initiated by intwaso, an illness understood to be a call from the ancestors, and guided by messages from the ancestors in dreams and other symbolic communications. The second is the perspective of Western Clinical Psychology on the cognitive, emotional and behavioural disturbances that characterise intwaso. The third is the perspective of transpersonal psychology on the nature and development of shamanic healing gifts, as understood from observations of such practices in traditional societies across the world. As the narrative of Nomzi’s story is quite long, this paper presents her narrative as well as the methodology which gave rise to it. The interpretative review of the material from each of the three perspectives is presented in a second paper. (shrink)

In this, the second of two papers, three interpretative investigations are undertaken of Nomzi’s story of her troubled childhood, her dreams of ancestors calling her to become an igqirha, her training by experienced healers, various rituals that were performed at different stages of her life, and her eventual graduation as an igqirha at the age of 61. The narrative cannot be understood apart from the framework of the isiXhosa traditional understanding of intwaso, the initiatory illness, the role of the ancestors, (...) and the manner in which clairvoyant abilities of divination and healing are developed under their guidance. Nomzi’s account, however, reflects a considerable modification of the tradition, several features of which she does not seem to understand herself. From a clinical psychological perspective, Nomzi’s behavioural disturbances in childhood, as well as her lifelong suspiciousness and paranoia, can be understood as a consequence of an unstable childhood in which there was no secure attachment, nor any adult guidance on emotional regulation of the kind needed to form the basis of a stable adult personality. From the perspective of transpersonal psychology, it seems likely that Nomzi was endowed with a degree of natural clairvoyance, but her development as a healer was impaired by displacement of her paranoid ideation into the role of witch-finder, and her chronic social alienation. (shrink)

Analysis of sites of newly integrated DNA in cellular genomes is important to several fields, but methods for analyzing and visualizing these datasets are still under development. Here, we describe tools for data analysis and visualization that take as input integration site data from our INSPIIRED pipeline. Paired-end sequencing allows inference of the numbers of transduced cells as well as the distributions of integration sites in target genomes. We present interactive heatmaps that allow comparison of distributions of integration sites to (...) genomic features and that support numerous user-defined statistical tests. To summarize integration site data from human gene therapy samples, we developed a reproducible report format that catalogs sample population structure, longitudinal dynamics, and integration frequency near cancer-associated genes. We also introduce a novel summary statistic, the UC50, which provides a single number summarizing possible clonal expansion. Using these tools, we characterize ongoing longitudinal characterization of a patient from the first trial to treat severe combined immunodeficiency-X1, showing successful reconstitution for 15 years accompanied by persistence of a cell clone with an integration site near the cancer-associated gene CCND2. Software is available at https://github.com/BushmanLab/INSPIIRED. (shrink)

Biomechanical engineering is marked by highly experimental efforts to craft mechanical devices that might one day alleviate the scarcity of transplantable organs in the USA. A pronounced desire among bioengineers involves melding humans with machines, bearing the promise of perfecting the natural yet messy flaws of the ‘natal’ body. Not all bodies are considered equal within this field, however. Visual renderings of heart devices — as an unusual sort of body prosthesis — foreground a specialized aesthetic, where the well-toned (...) class='Hi'>male form defines an idealized generic of beauty and perfection. This analysis considers the moral underpinnings of the embodied aesthetic in specific reference to engineers’ efforts to fabricate implantable ‘artificial’ hearts. Of central concern are the sociomoral consequences of a standardized male beauty, set alongside the striking absence — or invisibility — of the female form within this rarified field of science. (shrink)

Witty, sexy and radiantly beautiful, the Shelley translationof Plato's great Dialogue on Love is by far the best in theEnglish language. It has been described as conveying "much of the vivid life, the grace of movement, and the luminous beauty of Plato" -- "the poetry of a philosopher rendered by the prose of a poet." Although a masterpiece in its own right, the Shelley translation was suppressed and then bowdlerized for well over a century. In 19th century Britain, (...) class='Hi'>male love -- at the heart of the dialogue -- was unmentionable. The Banquet and Shelley's accompanying essay, "A Discourse on the Manners of the Antient Greeks," were not published in their entirety until 1931, and then in an edition of 100 copies intended "for private circulation only." The Pagan Press edition is complete, authentic and readable. For the first time this work has received the editing and typography it deserves. (shrink)

The field of neuroaesthetics attempts to identify the brain processes underlying aesthetic experience, including but not limited to beauty. Previous neuroaesthetic studies have focussed largely on paintings and music, while performing arts such as dance have been less studied. Nevertheless, increasing knowledge of the neural mechanisms that represent the bodies and actions of others, and which contribute to empathy, make a neuroaesthetics of dance timely. Here, we present the first neuroscientific study of aesthetic perception in the context of the (...) performing arts. We investigated brain areas whose activity during passive viewing of dance stimuli was related to later, independent aesthetic evaluation of the same stimuli. Brain activity of six naïve male subjects was measured using fMRI, while they watched 24 dance movements, and performed an irrelevant task. In a later session, participants rated each movement along a set of established aesthetic dimensions. The ratings were used to identify brain regions that were more active when viewing moves that received high average ratings than moves that received low average ratings. This contrast revealed bilateral activity in the occipital cortices and in right premotor cortex. Our results suggest a possible role of visual and sensorimotor brain areas in an automatic aesthetic response to dance. This sensorimotor response may explain why dance is widely appreciated in so many human cultures. (shrink)