Digital technologies hold promise to modernize healthcare. Such opportunity should be leveraged also to address the needs of rapidly ageing populations. Against this backdrop, this paper examines the use of wearable devices for promoting healthy ageing. Previous work has assessed the prospects of digital technologies for health promotion and disease prevention in older adults. However, to our knowledge, ours is one of the first attempts to specifically address the use of wearables for healthy ageing, and to offer ethical insights for (...) assessing the prospects of leveraging wearable devices in this context. We provide an analysis of the considerable opportunities associated with the use of wearables for healthy ageing, with a focus on the five domains of intrinsic capacity: locomotion, sensory functions, psychological aspects, cognition, and vitality. We then highlight current limitations and ethical challenges of such approach to healthy ageing, including issues related to access, inclusion, privacy, surveillance, autonomy, and regulation. We conclude by discussing the implications of our analysis in light of current debates on the ethics of digital health, and suggest measures to address the identified challenges. (shrink)

Wearable devices are increasingly present in the health context, as tools for biomedical research and clinical care. In this context, wearables are considered key tools for a more digital, personalised, preventive medicine. At the same time, wearables have also been associated with issues and risks, such as those connected to privacy and data sharing. Yet, discussions in the literature have mostly focused on either technical or ethical considerations, framing these as largely separate areas of discussion, and the contribution of wearables (...) to the collection, development, application of biomedical knowledge has only partially been discussed. To fill in these gaps, in this article we provide an epistemic (knowledgerelated) overview of the main functions of wearable technology for health: monitoring, screening, detection, and prediction. On this basis, we identify 4 areas of concern in the application of wearables for these functions: data quality, balanced estimations, health equity, and fairness. To move the field forward in an effective and beneficial direction, we present recommendations for the 4 areas: local standards of quality, interoperability, access, and representativity. (shrink)

In this commentary, I discuss the scientific changes brought by the exposome, asking what is new about this approach and line of research. I place the exposome in a historical perspective, by analyzing the conditions under which the exposome has been conceived, developed and established in the context of contemporary epidemiological research. I argue that the exposome has been developed by transferring approaches, methods and conceptualizations from other lines of research in the life and health sciences. I thus discuss the (...) conceptual and methodological innovations of the exposome as a result of the merging and adaptation of these elements for new uses and purposes. On this basis, I argue that the novelty of the exposome should be seen in incremental rather than revolutionary terms and, in this sense, the exposome shares significant elements with other projects and repertoires in postgenomics. I conclude by discussing the consequences of this analysis for the potential limitations and future development of exposome research. (shrink)

Name der Zeitschrift: Deutsche Zeitschrift für Philosophie Jahrgang: 65 Heft: 1 Seiten: 67-88.

‘Philosophical dialogue’ indicates both a form of philosophical inquiry and its corresponding literary genre. In its written form, it typically features two or more characters who engage in a discussion concerning morals, knowledge, as well as a variety of topics that can be widely labelled as ‘philosophical’. Our philosophical dialogue takes place in Krakow, Poland. It is a rainy morning and two strangers are waiting at a tram stop. One of them is dressed neatly, and cannot stop fidgeting with his (...) closed umbrella. The other was caught unprepared by the morning downpour and water is dripping from his worn, soaked jacket. (shrink)

Presenting a critical history of the philosophy of science in the twentieth century, focusing on the transition from logical positivism in its first half to the ...

This book seeks to rectify misrepresentations of Popperian thought with a historical approach to Popper’s philosophy, an approach which applies his own mature view, that we gain knowledge through conjectures and refutations, to his own development, by portraying him in his intellectual growth as just such a series. Gattei seeks to reconstruct the logic of Popper’s development, in order to show how one problem and its tentative solution led to a new problem.

Recently, there has been increasing interest in methodological aspects of advanced imaging, including the role of guidelines, recommendations, and experts’ consensus, the practice of self-referral, and the risk of diagnostic procedure overuse. In a recent Delphi study of the European Association for Nuclear Medicine (EANM), panelists were asked to give their opinion on 47 scientific questions about imaging in prostate cancer. Nine additional questions exploring the experts’ attitudes and opinions relating to the procedure of consensus building itself were also included. (...) The purpose was to provide insights into the mechanism of recommendation choice and consensus building as seen from the experts’ point of view. Results: Regarding the factors likely to influence the willingness to refer a patient for imaging, the most voted were incorporation into guidelines and data from scientific literature, while personal experience and personal relationship were chosen by a small minority. Regarding the recommendations more relevant to prescribe an imaging procedure, it resulted the incorporation into guidelines promoted by scientific societies (59% of votes); these guidelines also resulted the more trusted. With respect to patients’ preferences considered when prescribing an imaging procedure, the most voted was accuracy, resulted more important than easy access and time to access to the procedure. The majority of the experts expressed the opinion that there is a scarce use of imaging procedures in prostate cancer. With respect to the most relevant factor to build consensus, it resulted the transparency of the process (52% of votes), followed by multidisciplinarity of contributors. The main obstacle to incorporation of modern imaging procedures into guidelines resulted the lack of primary literature on clinical impact. Conclusions: Firstly, the panelists portray themselves as having Evidence-Based Medicine oriented and scientifically inclined attitudes and preferences. Secondly, guidelines and recommendations from scientific societies, especially clinical ones, are positively taken into account as factors influencing decisions, but panelists tend to consider their own appraisal of the scientific literature as more relevant. Thirdly, in respect of overuse, panelists do not think that advanced diagnostic procedures are overutilized in the specific case of Prostate Cancer, but rather they are underutilized. (shrink)

Antonio Signorini’s contribution to the constitutive theory of non-linear elasticity is reconstructed and analyzed. Some uninformed opinions suggesting he had a minor role, lacking of significant results, are discussed and refuted. It is shown that Signorini should be rightly credited for being among the first scholars aware of the central problem of non-linear elasticity: the determination of the general form of the elastic potential.

The discussion on the 900 Conclusiones projected and sponsored by Giovanni Pico della Mirandola in Rome was cut short by the condemnation of 13 of them by the papal commission in 1487. Princeps Concordiae’s counter-arguments presented in his Apologia, published in the same year, can not be certainly considered a disputatio as Pico had called for; the papal intervention removed in this way the possibility to have a better acquaintance with a work which is still a very difficult one, just (...) for its “unfinished” form. Pedro Garsia’s Determinationes magistrales against Pico’s Apologia are a very poor reply to Pico. In this paper Pico’s arguments against some of the condemned Conclusiones are considered as well as Pedro Garsia’s counter-arguments. Giovanni Pico della Mirandola displays a deep familiarity with medieval logical and semantical doctrines, while Pedro Garsia’s arguments betray a solid ignorance. (shrink)

This volume features forty-two essays written in honor of Joseph Agassi. It explores the work and legacy of this influential philosopher, an exciting and challenging advocate of critical rationalism. Throughout six decades of stupendous intellectual activity, Agassi called attention to rationality as the very starting point of every notable philosophical way of life. The essays present Agassi’s own views on critical rationalism. They also develop and expand upon his work in new and provocative ways. The authors include Agassi's most notable (...) pupils, friends, and colleagues. Overall, their contributions challenge the received view on a variety of issues concerning science, religion, and education. Readers will find well-reasoned arguments on such topics as the secular problem of evil, religion and critical thinking, liberal democratic educational communities, democracy and constitutionalism, and capitalism at a crossroad.“/div>divTo Joseph Agassi, philosophy is the practice of reason, where reason is understood as the relentless search for criticisms of the best available explanations that we have to the world around us. This book not only honors one of the most original philosophers of science today. It also offers readers insights into a school of thought that lies at the heart of philosophy. (shrink)

This book seeks to rectify misrepresentations of Popperian thought with a historical approach to Popper’s philosophy, an approach which applies his own mature view, that we gain knowledge through conjectures and refutations, to his own development, by portraying him in his intellectual growth as just such a series. Gattei seeks to reconstruct the logic of Popper’s development, in order to show how one problem and its tentative solution led to a new problem.

With a preface by Gianni Vattimo, this book offers both an overview of contemporary Italian philosophy and a new interpretation of Nietzsche’s ‘God is Dead’ in connection with the notion of freedom as the original dynamic of the will to power.

This paper is the written version of my contribution to the International Conference «30 years Logica modernorum» held in Amsterdam in November 1997 in honor of the late prof. Lambertus M. de Rijk. Research on Oresme’s modi rerum theory was in the first stage, while now we can read the critical edition of Oresme’s Physics commentary, where modi are introduced and widely used. In this paper I shall consider Oresme’s polemical use of modi rerum, trying to set it in the (...) larger context of both his ontology and his epistemology. Oresme’s challenge to either a realist or terminist ontology by means of modi rerum conceals probably an attack to William of Ockham; Oresme refers explicitly to Ockham concerning exclusive propositions, but I think that on many other occasions the polemical target of Oresme’s criticism can be reasonably identified in William of Ockham or in some unnamed followers of the Venerabilis Inceptor. Some hints are reserved also to the possible sources of Oresme’s modi rerum. (shrink)

This collection of the writings of Paul Feyerabend is focused on his philosophy of quantum physics, the hotbed of the key issues of his most debated ideas. Written between 1948 and 1970, these writings come from his first and most productive period. These early works are important for two main reasons. First, they document Feyerabend's deep concern with the philosophical implications of quantum physics and its interpretations. These ideas were paid less attention in the following two decades. Second, the writings (...) provide the crucial background for Feyerabend's critiques of Karl Popper and Thomas Kuhn. Although rarely considered by scholars, Feyerabend's early work culminated in the first version of Against Method. These writings guided him on all the key issues of his most well-known and debated theses, such as the incommensurability thesis, the principles of proliferation and tenacity, and his particular version of relativism, and more specifically on quantum mechanics. (shrink)

In this chapter we explore Feyerabend’s relationship to Karl Marx, with a focus on their respective views on politics. Our main topics include the nature and dynamics of political change, the idea of the 'free society', and the ends of political activity.

Having been found ‘vehemently suspected of heresy’ by the Holy Office in 1633, at the time of his death Galileo's remains were laid to rest in the tiny vestry of a lateral chapel of the Santa Croce Basilica, Florence. Throughout his life, Vincenzo Viviani, Galileo's last disciple, struggled to have his master's name rehabilitated and his banned works reprinted, as well as a proper funeral monument erected. He did not live to see all this come true, but his efforts triggered (...) a mechanism that eventually led to the fulfilment of his wishes. A key element of his project was the transformation of the facade of his palace into a private tribute to Galileo, with two long inscriptions celebrating Galileo's achievements and calling Florence's attention to the need to pay a proper tribute to him. Shortly afterwards, he revised the text and circulated it in print. This article presents the first critical edition and annotated translation of Viviani's original manuscript, long thought to be lost, and describes its role in Viviani's lifelong struggle for Galileo's intellectual legacy, as well as its impact on future historiography. (shrink)

In Towards an Historiography of Science (1963) and in other related works spanning over his entire career, Agassi presents his wide-ranging and original understanding of the history of science. It emerges from the criticism of two distinctive approaches, each informed by the uncritical acceptance, on the part of historians, of two philosophies of science: inductivism (scientific theories emerge from facts), and conventionalism (scientific theories are mathematical frameworks for classifying facts). Both produce unsatisfactory historical reconstructions, in which errors are either concealed (...) or condemned. Popper’s philosophy, by contrast, allows for a picture in which science grows from the recognition and criticism of our best and wisest errors. (shrink)

In Towards an Historiography of Science (1963) and in other related works spanning over his entire career, Agassi presents his wide-ranging and original understanding of the history of science. It emerges from the criticism of two distinctive approaches, each informed by the uncritical acceptance, on the part of historians, of two philosophies of science: inductivism (scientific theories emerge from facts), and conventionalism (scientific theories are mathematical frameworks for classifying facts). Both produce unsatisfactory historical reconstructions, in which errors are either concealed (...) or condemned. Popper’s philosophy, by contrast, allows for a picture in which science grows from the recognition and criticism of our best and wisest errors. (shrink)

In Augustinus Niphus’ commentary on Aristotle’s Physics some marginal annotations can be considered an aide-mémoire for teachers commenting Aristotle’s text. In these annotations titles of questions concerning problems raised by Aristotle’s discussion on motion are recorded together with some medieval and renaissance comments. The analysis of these annotations is limited to the pages of the discussion on vacuum.

Per conoscere la medicina sono necessari strumenti teorici, pratici, tecnologici e culturali, ma non solo: come mostra il volume, anche la riflessione filosofica può svolgere un ruolo cruciale sui suoi vari aspetti. Analizzando esempi concreti e grazie ai contributi di medici, epidemiologi e ingegneri, il libro fornisce strumenti filosofici per leggere le caratteristiche fondamentali della medicina contemporanea, i suoi recenti sviluppi e le sfide che è chiamata ad affrontare: una lente di grande utilità per la formazione dei medici e per (...) la ricerca dei filosofi che vogliano guardare realmente da vicino le scienze biomediche. (shrink)