Background: There is a growing interest in using cognitive behavioural therapy with people who have Asperger Syndrome and comorbid mental health problems. Aims: To examine whether modified group CBT for clinically significant anxiety in an AS population is feasible and likely to be efficacious. Method: Using a randomised assessor-blind trial, 52 individuals with AS were randomised into a treatment arm or a waiting-list control arm. After 24 weeks, those in the waiting-list control arm received treatment, while those initially randomised to (...) treatment were followed-up for 24 weeks. Results: The conversion rate for this trial was high, while attrition was 13%. After 24 weeks, there was no significant difference between those randomised to the treatment arm compared to those randomised to the waiting-list control arm on the primary outcome measure, the Hamilton Rating Scale for Anxiety. Conclusions: Trials of psychological therapies with this population are feasible. Larger definitive trials are now needed. Declaration of Interest: None Trial Registration: ISRCTN 30265294, UKCRN 8370. (shrink)

Plato. Crito.--Mill, J. S. Utilitarianism.--Rawls, J. Two concepts of rules.--Kant, I. Fundamental principles of the metaphysic of morals.--Rawls, J. Justice as fairness.--Benn, S. I. and Peters, R. S. Society and types of social regulation.--Hobbes, T. Leviathan, abridged.--Hayek, F. A. The principles of a liberal social order.--Marx, K. Alienation and its overcoming in Communism.--Lukes, S. Alienation and anomie.--Garver, N. What violence is.--Zinn, H. The force of nonviolence.--Caudwell, C. Pacifism and violence; a study in bourgeois ethics.--Bennett, J. Whatever the consequences.--Foot, P. Abortion (...) and the doctrine of the double effect.--Benn, S. I. Punishment.--Mill, J. S. Selection from On liberty.--Mill, J. S. Selection from Considerations on representative government.--Marcuse, H. The new forms of control.--Mill, J. S. The subjection of women, abridged.--Dickinson, J. A working theory of sovereignty, abridged.--Rawls, J. The justification of civil disobedience. (shrink)

The classic, influential essay in 'descriptive metaphysics' by the distinguished English philosopher.

All developed human beings possess a practical mastery of a vast range of concepts, including such basic structural notions as those of identity, truth, existence, material objects, mental states, space, and time; but a practical mastery does not entail theoretical understanding. It is that understanding which philosophy seeks to achieve. In this book, one of the most distinguished of living philosophers, assuming no previous knowledge of the subject on the part of the reader, sets out to explain and illustrate a (...) certain conception of the nature of analytical philosophy. Strawson draws on his many years of teaching at Oxford University, during which he refined and developed what he regards as the most productive route to understanding the fundamental structure of human thinking. Among the distinctive features of his exposition are the displacement of an older, reductive conception of philosophical method in favor of elucidating the interconnections between the complex but irreducible notions which form the basic structure of our thinking; and the demonstration that the three traditionally distinguished departments of metaphysics, epistemology, and logic are but three aspects of one unified enquiry. Strawson has produced an elegant work that will be invaluable to students and stimulating for professional philosophers and general readers alike. (shrink)

The species-specific organizational property of speech is a continual mouth open-close alternation, the two phases of which are subject to continual articulatory modulation. The cycle constitutes the syllable, and the open and closed phases are segments framescontent displays that are prominent in many nonhuman primates. The new role of Broca's area and its surround in human vocal communication may have derived from its evolutionary history as the main cortical center for the control of ingestive processes. The frame and content components (...) of speech may have subsequently evolved separate realizations within two general purpose primate motor control systems: (1) a motivation-related medial system, including anterior cingulate cortex and the supplementary motor area, for self-generated behavior, formerly responsible for ancestral vocalization control and now also responsible for frames, and (2) a lateral system, including Broca's area and surround, and Wernicke's area, specialized for response to external input (and therefore the emergent vocal learning capacity) and more responsible for content. (shrink)

Among the objections to the implementation of what I will call "genome editing in human reproduction" is that it does not address any unmet medical need, and therefore fails to meet an important criterion for introducing an unproven procedure with potentially adverse consequences. To be clear: what I mean by GEHR is the use of any one of a number of related biological techniques, such as the CRISPR-Cas9 system, deliberately to modify a functional sequence of DNA in a cell of (...) a human embryo, so that the modified sequence is replicated in the cells of a resulting child and may, without further intervention, be passed on to that child's biological descendants. It is... (shrink)

History reveals how civilisations can be decimated by changes in climate. More recently modern methods of warfare have exposed the vulnerability of the artefacts of civilisation. Bringing together a range of subjects - from science, energy and sustainability to aesthetics theory and civilization theory - this book uniquely deals with climate change and the ensuing catastrophes in relation to cultural factors, urbanism and architecture. It links the evolution of civilisation, with special emphasis on the dynamics of beauty as displayed in (...) architecture and urbanism, to climate change. It then considers both the historic and predicted impacts of climate change and the threat it poses to the continued viability of human civilisation when survival is the top priority. This book gives students, researchers and professionals in architecture and sustainable design as well as anyone interested in the threat of global warming to civilisation, new insights as to what could be lost if action is not taken at a global level. (shrink)

An action-oriented perspective changes the role of an individual from a passive observer to an actively engaged agent interacting in a closed loop with the world as well as with others. Cognition exists to serve action within a landscape that contains both. This chapter surveys this landscape and addresses the status of the pragmatic turn. Its potential influence on science and the study of cognition are considered (including perception, social cognition, social interaction, sensorimotor entrainment, and language acquisition) and its impact (...) on how neuroscience is studied is also investigated (with the notion that brains do not passively build models, but instead support the guidance of action). A review of its implications in robotics and engineering includes a discussion of the application of enactive control principles to couple action and perception in robotics as well as the conceptualization of system design in a more holistic, less modular manner. Practical applications that can impact the human condition are reviewed (e.g., educational applications, treatment possibilities for developmental and psychopathological disorders, the development of neural prostheses). All of this foreshadows the potential societal implications of the pragmatic turn. The chapter concludes that an action-oriented approach emphasizes a continuum of interaction between technical aspects of cognitive systems and robotics, biology, psychology, the social sciences, and the humanities, where the individual is part of a grounded cultural system. (shrink)

The Frame/Content theory deals with how and why the first language evolved the present-day speech mode of programming syllable “Frame” structures with segmental “Content” elements. The first words are considered, for biomechanical reasons, to have had the simple syllable frame structures of pre-speech babbling, and were perhaps parental terms, generated within the parent–infant dyad. Although all gestural origins theories have iconicity as a plausible alternative hypothesis for the origin of the meaning-signal link for words, they all share the problems of (...) how and why a fully fledged sign language, necessarily involving a structured phonology, changed to a spoken language. (shrink)

I expressed agreement with Unger's view of the essential\nnature of personal identity, but dissented from what I took\nto be his view of the value we attach to its preservation;\nsaying, for example, that, in common, I think with many\nothers, I would prefer being replaced or succeeded' by a\nnumerically distinct continuator' with "qualitatively"\nidentical memories and mental and physical characteristics\nto surviving as the "numerically" identical person with\nsevere impairment of memory and abilities.

Essays that put noted political thinkers of the past—including Plato, Machiavelli, Hobbes, Wollstonecraft, Marx, and Confucius—in dialogue with current environmental political theory. Contemporary environmental political theory considers the implications of the environmental crisis for such political concepts as rights, citizenship, justice, democracy, the state, race, class, and gender. As the field has matured, scholars have begun to explore connections between Green Theory and such canonical political thinkers as Plato, Machiavelli, Locke, and Marx. The essays in this volume put important figures (...) from the political theory canon in dialogue with current environmental political theory. It is the first comprehensive volume to bring the insights of Green Theory to bear in reinterpreting these canonical theorists. Individual essays cover such classical figures in Western thought as Aristotle, Hume, Rousseau, Mill, and Burke, but they also depart from the traditional canon to consider Mary Wollstonecraft, W. E. B. Du Bois, Hannah Arendt, and Confucius. Engaging and accessible, the essays also offer original and innovative interpretations that often challenge standard readings of these thinkers. In examining and explicating how these great thinkers of the past viewed the natural world and our relationship with nature, the essays also illuminate our current environmental predicament. Essays on Plato • Aristotle • Niccolò Machiavelli • Thomas Hobbes • John Locke • David Hume • Jean-Jacques Rousseau • Edmund Burke • Mary Wollstonecraft • John Stuart Mill • Karl Marx • W. E. B. Du Bois • Martin Heidegger • Hannah Arendt • Confucius Contributors Sheryl D. Breen, W. Scott Cameron, Peter F. Cannavò, Joel Jay Kassiola, Joseph H. Lane Jr. Timothy W. Luke, John M. Meyer, Özgüç Orhan, Barbara K. Seeber, Francisco Seijo, Kimberly K. Smith, Piers H. G. Stephens, Zev Trachtenberg, Andrew Valls, Harlan Wilson. (shrink)

Henry David Thoreau, though often characterised as individualist or apolitical, is in fact an important link between Jeffersonian agrarian republicanism and environmentalism. Like the Jeffersonians, Thoreau espouses a political economy of citizenship, criticises modern capitalism, and celebrates simplicity and personal independence. However, Thoreau rejects the Jeffersonians' focus on conquest of the wilderness and economic industriousness, both of which were meant to promote virtue. Thoreau advocates preservation of wild nature as essential for cultivating virtue and regards nature as a community deserving (...) respect and protection. He criticises an emphasis on economic industriousness as promoting overwork, environmental destruction and greed. Thoreau emerges as a complex figure whose legacy points in two contrasting directions: toward a more ecologically responsible or sustainable republicanism embracing preservation of a spectrum of landscapes from wilderness to agrarian, and also toward a problematic, depoliticising separation between human beings and nature. (shrink)

This work describes the concept of bond order. It shows that covalent bond energy is correlated to bond order. Simple expressions which included bond order are introduced to calculate bond energies of homo-nuclear and hetero-nuclear bonds. Calculated values of bond energies are compared with literature values and show there is very good agreement between and calculated and experimental values in the vast majority of cases. Bond order reveals the strength of a bond and shows the number of bonds in both (...) homo-nuclear and hetero-nuclear covalent bonds. (shrink)

Phrasal semantics is concerned with how the meaning of a sentence is composed both from the meaning of the constituent words, and from extra meaning contained within the structural organization of the sentence itself. In this context, grammatical constructions correspond to form-meaning mappings that essentially capture this “extra” meaning and allow its representation. The current research examines how a computational model of language processing based on a construction grammar approach can account for aspects of descriptive, referential and information content of (...) phrasal semantics. (shrink)

This article reexamines the classical distinction between professional and organizational work orientations for the case of engineers. Based on data from a survey questionnaire mailed to a sample of 800 engineers in the Rochester, New York, area in 1986, it argues that the two orientations are not opposites. Instead, it is possible to score high on measures of both orientations, or to score low on both. The result is a more complex, fourfold typology of engineers' work orientations. This fourfold typology (...) is then applied to the analysis of engineers' job satisfaction. The most important finding is that the content of engineers' work—that is, the level of challenge and the intrinsic interest of the work—is the central predictor of their satisfaction. The results thus support the conjecture that contemporary engineers have become highly focused—perhaps overly focused—on the gratifications derived from technical work as a process. (shrink)

This paper examines how people in West Africa are reacting to the Ebola virus disease, an epidemic presently prevalent in the region. Certain lifestyle changes are suggested. Additionally, the heart of the paper focuses on the request by governments to be allowed access to experimental drugs, such as Zmapp and TKM-Ebola, for their infected populations. The author argues that granting such a request would circumvent research ethics procedures, which could potentially constitute significant risk to users of the drugs. The Pfizer (...) Kano meningitis trial of 1996 is cited as an example to buttress how unapproved drugs could prove fatal. (shrink)

We endorse Davey's view that expectancy processes are intimately involved in fear reactions, but question his model on three grounds. First, the mechanism for generating expectancy bias to both ontogenetic and phylogenetic stimuli is not spelled out. Second, the selective association component is unnecessary. Third, the model fails to provide a clear explanation for the irrationality of phobic reactions.