The literature on deep brain stimulation (DBS) and adaptive DBS (aDBS) raises concerns that these technologies may affect personality, mood, and behavior. We conducted semi-structured interviews with researchers (n = 23) involved in developing next-generation DBS systems, exploring their perspectives on ethics and policy topics including whether DBS/aDBS can cause such changes. The majority of researchers reported being aware of personality, mood, or behavioral (PMB) changes in recipients of DBS/aDBS. Researchers offered varying estimates of the frequency of PMB changes. A (...) smaller majority reported changes in personality specifically. Some expressed reservations about the scientific status of the term ‘personality,’ while others used it freely. Most researchers discussed negative PMB changes, but a majority said that DBS/aDBS can also result in positive changes. Several researchers viewed positive PMB changes as part of the therapeutic goal in psychiatric applications of DBS/aDBS. Finally, several discussed potential causes of PMB changes other than the device itself. (shrink)

This study examined some ethical implications of two different individual competitive orientations. Winning is crucially important in hypercompetitiveness , whereas a personal development (PD) perspective considers competition as a means to self-discovery and self-improvement. In a sample of 263 senior-level undergraduate business students, survey results suggested that hypercompetitiveness was generally associated with “poor ethics” and PD competitiveness was linked with “high ethics”. For example, hypercompetitive individuals generally saw nothing wrong with self-interested gain at the expense of others, but PD competitors (...) viewed such activities as largely inappropriate. Hypercompetitive people also tended to be highly Machiavellian but not ethically idealistic. In contrast, PD competitors tended to be ethically idealistic but not Machiavellian. Managers that are interested in both high ethics and high functioning work groups may wish to consider the potential importance of attempting to channel hypercompetitive tendencies into PD directions. (shrink)

The mere presence of irrelevant external stimuli results in interference with the fidelity of details retrieved from long-term memory (LTM). Recent studies suggest that distractibility during LTM retrieval occurs when the focus of resource-limited, top-down mechanisms that guide the selection of relevant mnemonic details is disrupted by representations of external distractors. We review findings from four studies that reveal distractibility during episodic retrieval. The approach cued participants to recall previously studied visual details when their eyes were closed, or were open (...) and irrelevant visual information was present. The results showed a negative impact of the distractors on the fidelity of details retrieved from LTM. An fMRI experiment using the same paradigm replicated the behavioral results and found that diminished episodic memory was associated with the disruption of functional connectivity in whole-brain networks. Specifically, network connectivity supported recollection of details based on visual imagery when eyes were closed, but connectivity declined in the presence of visual distractors. Another experiment using auditory distractors found equivalent effects for auditory and visual distraction during cued recall, suggesting that the negative impact of distractibility is a domain-general phenomenon in LTM. Comparisons between older and younger adults revealed an aging-related increase in the negative impact of distractibility on retrieval of LTM. Finally, a new study that compared categorization abilities between younger and older adults suggests a cause underlying age-related decline of visual details in LTM. The sum of our findings suggests that cognitive control resources, although limited, have the capability to resolve interference from distractors during tasks of moderate effort, but these resources are overwhelmed when additional processes associated with episodic retrieval, or categorization of complex prototypes, are required. (shrink)

Jones (1990) described ten workplace behaviors of a dubious ethical nature and determined that the hierarchical position adopted by respondents influenced the perceived acceptability of these behaviors. This measure seems promising, and therefore the purpose of this investigation is two-fold: (1) to explore further the psychometric properties of these ten items; and (2) to examine the role of individual difference variables as correlates of perceived acceptability. In two samples of working people, the Jones items were found to be internally consistent, (...) not obviously subject to range restriction, modestly related to social desirability, largely orthogonal to age and managerial status, but clearly linked with Machiavellianism. The nature of the linkage between perceived acceptability and both sex and the Protestant work ethic differed across the two studies, which underscores the need for future research. Two additional variables worth investigating in such research may be locus of control and equity sensitivity. (shrink)

Knowledge about ethical judgments has not advanced appreciably after decades of research. Such research, however, has rarely addressed the possible importance of the content of such judgments; that is, the material appearing in the brief vignettes or scenarios on which survey respondents base their evaluations. Indeed, this content has seemed an afterthought in most investigations. This paper closely examined the vast array of vignettes that have appeared in relevant research in an effort to reduce this proliferation to a more concise (...) set of overarching vignette themes. Six generic themes emerged from this process, labeled here as Dilemma, Classic, Conspiracy, Sophie’s Choice, Runaway Trolley, and Whistle Blowing. Each of these themes is characterized by a unique combination of four key factors that include the extent of protagonist personal benefit from relevant vignette activities and victim salience in vignette descriptions. Theme identification enabled inherent ambiguities in vignettes that threaten construct validity to come into sharp focus, provided clues regarding appropriate vignette construction, and may help to make sense of patterns of empirical findings that heretofore have seemed difficult to explain. (shrink)

Ensemble musicians play in synchrony despite expressively motivated irregularities in timing. We hypothesized that synchrony is achieved by each performer internally simulating the concurrent actions of other ensemble members, relying initially on how they would perform in their stead. Hence, musicians should be better at synchronizing with recordings of their own earlier performances than with others’ recordings. We required pianists to record one part from each of several piano duets, and later to play the complementary part in synchrony with their (...) own or others’ recordings. The pianists were also asked to identify their own recordings. The pianists were better at synchronizing with their own than with others’ performances, and they were able to recognize their own recordings. Furthermore, synchronization accuracy and recognition were correlated: Pianists who were relatively accurate at synchronizing with their own performances were also good at recognizing them. Thus, action simulation may underlie both synchronization and self-recognition. (shrink)

The construct of cognitive moral development seemingly has powerful practical relevance in many areas of life. Nonetheless, moral reasoning seems of marginal relevance at best in the context of business ethics. Simply put, moral reasoning measurement indices are often only weakly related to many other apparently pertinent variables, and such findings cast doubt upon the construct validity of cognitive moral development. Many such unexpectedly weak relationships, however, may stem from two largely unrecognized methodological artifacts. The first artifact is an almost (...) total reliance on the P index of the Defining Issues Test (DIT) designed to assess moral development even when this index may be inappropriate in a particular context. A second artifact that seems particularly salient in the context of attitudes toward authority involves a not always appropriate reliance on samples that include respondents whose moral reasoning is uncoupled from their action choices. These artifacts may restrict the amount of variance explained in observed relationships, and thus constrain the potential for moral reasoning to understand and explain behavior and attitudes relevant in the context of business ethics. Researchers are urged to use DIT D scores (in addition to P scores) in specific situations, and to examine relationships among high DIT U scorers whose moral reasoning is tightly coupled with their action choices. The application of these guidelines may have profound implications for advancing our fundamental understanding of moral reasoning, and of increasing its relevance to business ethics. (shrink)

Two contrasting types of individuals were each predicted to agree, for different reasons, that conventional ethical standards of society need not be upheld if organizational interests appear to demand otherwise. The hypotheses were investigated using questionnaire responses from two samples (employed and student, total N=308). Clear support was obtained for the prediction that individuals inclined toward self-interest and behavior counter to conventional standards would agree with the preceding position. Partial support was obtained for the hypothesis that individuals who simply feel (...) obligated to support an employing organization would also agree. While the latter's perspective may be somewhat narrow or perhaps even cynical, they do not seem to reflect the self-interest profile of the first group. This study also extends the groundbreaking work of Froelich and Kottke by exploring individual difference correlates of their promising ethics scale assessing the extent of agreement that organizational interests legitimately supersede more conventional ethical standards. (shrink)

DNA topoisomerase II (topo II) is involved in chromosome structure and function, although its exact location and role in mitosis are somewhat controversial. This is due in part to the varied reports of its localization on mitotic chromosomes, which has been described at different times as uniformly distributed, axial on the chromosome arms and predominantly centromeric. These disparate results are probably due to several factors, including use of different preparation and fixation techniques, species differences and changes in distribution during the (...) cell cycle. Recently, several papers have re‐investigated the distribution of topo II on chromosomes as a function of cell cycle and species(1–3). The new studies suggest that Topo II has a dynamic pattern of distribution on the chromosomes, in general becoming axial as chromosomes condense during prophase and then concentrating at centromeres during metaphase. These experiments suggest a novel role for topo II in centromere structure and function. (shrink)

The harsh consequences of the American plant closing epidemic in recent years on workers, their families, and their communities, has raised widespread ethical and moral concerns. In the early 1970s, a diverse group of academics, social activists, public policy analysts, and special interest organizations developed a number of legislative proposals designed to restrict closings by law. The proposals encountered many formidable obstacles in an increasingly hostile free-market environment. The business community was itself moved to assume some of the burdens precipitated (...) by closures either unilaterally or through collective bargaining. At the same time, powerful business interests tenaciously fought the enactment of mandatory closing restrictions into law. Nevertheless, through a prolonged and tortuous odyssey, the requirements of advanced notice and worker severence pay have now begun to root in law. Their success stands as evidence of a continuing American public policy receptivity to ethics-driven concerns. (shrink)

Al-Kindī, honoured as the 'philosopher of the Arabs', was the first philosopher of Islam. His pioneer philosophical writings engage with ideas that became available through the Graeco-Arabic translation movement. This volume makes his entire philosophical output-some two dozen works-available in English, most of them for the first time. An overall introduction, introductions to each work and extensive notes explain al-Kindī's ideas, sources, and influence.

Background: There is a growing interest in using cognitive behavioural therapy with people who have Asperger Syndrome and comorbid mental health problems. Aims: To examine whether modified group CBT for clinically significant anxiety in an AS population is feasible and likely to be efficacious. Method: Using a randomised assessor-blind trial, 52 individuals with AS were randomised into a treatment arm or a waiting-list control arm. After 24 weeks, those in the waiting-list control arm received treatment, while those initially randomised to (...) treatment were followed-up for 24 weeks. Results: The conversion rate for this trial was high, while attrition was 13%. After 24 weeks, there was no significant difference between those randomised to the treatment arm compared to those randomised to the waiting-list control arm on the primary outcome measure, the Hamilton Rating Scale for Anxiety. Conclusions: Trials of psychological therapies with this population are feasible. Larger definitive trials are now needed. Declaration of Interest: None Trial Registration: ISRCTN 30265294, UKCRN 8370. (shrink)

"A learned work of rhetoric... compiled and made in the English tongue, of [one] who in judgment is profound, in wisdom and eloquence most famous." Thus in 1563 rhetorician Richard Rainolde praised _The Art of Rhetoric_, the work that brought into English the procedures of Ciceronian rhetoric-invention, disposition, style, memory, and delivery—the core of the academic curriculum in Renaissance England. Written in vigorous, native English, the _Art_ went through eight editions between 1553 and 1585. At least part of its appeal (...) was practicality. On the final page of his copy on Quintilian, Gabriel Harvey noted that _The Art of Rhetoric _is the "Daily bread of our common pleaders and discoursers." But its appeal was also academic. In 1619, nearly forty years after the _Art_ had lapsed from print, John Milton's teacher Alexander Gill invoked Wilson as he ridiculed the affectations of pretentiously learned language. Seen in its historical context, Wilson's _The Art of Rhetoric _reveals a great deal about the formal education of such authors as Shakespeare, Spenser, Jonson, and Milton. Since it bears directly on what is basic to imaginative literature—the art of language—the _Art_ encapsulates a literary context relevant to all those studying the English Renaissance, whether their approach is historicist, structuralist, deconstructionist, or new historicist. In addition, it will be of interest to students of rhetoric, education, and intellectual history in general. There have been four editions of the _Art_ in the twentieth century: two facsimiles and two original-spelling texts, none of which is in print. Peter Medine's edition modernizes the spelling and punctuation of the text of the second edition, which Wilson revised and expanded in 1560, and furnishes a fully critical apparatus, including introduction, textual notes, commentary, and glossary. As such, this edition makes available a central work of the English Renaissance in an accessible format. (shrink)

Philosophy courses face unique problems in that students generally have no previous encounter with the subject and have serious misconceptions about its nature and relevance. This paper presents an essay “What Makes the Examined Life Worth Living” that provides students an accessible introduction to philosophy; one that corrects their suspicion that philosophy is nothing more than opinion, where no progress is made, and has no practical importance. The essay begins by replacing the practice of philosophy as merely asserting one’s opinion (...) with philosophy as analysis and argument about fundamental questions, turns to a discuss of progress in philosophy, and concludes with four replies to the view that philosophy lacks practical relevance. (shrink)

In an article published recently in theJournal of Business Ethics, Vitellet al. (1991) found that elderly respondents scored surprisingly high on a measure of Machiavellianism. This paper offers an alternative explanation for this unexpected result — it may be an artifact of the survey format employed — and recommends additional research to help clarify the issues raised by Vitell and his colleagues.

Aristotle Poetics: Editio Maior of the Greek Text with Historial Introductions and Philological Commentaries. Edited by Leonardo Tarán and Dimitri Gutas. Mnemosyne Supplements, vol. 338. Leiden: Brill, 2012. Pp. xiii + 536. $226, €162.

Night falls on war-weary Troy after a day of celebration, setting the stage for the final agony of the city: uertitur interea caelum et ruit Oceano nox inuoluens umbra magna terramque polumque Myrmidonumque dolos.

Hugely facilitated by the Internet, plagiarism by students threatens educational quality and professional ethics worldwide. Plagiarism reduces learning and is correlated with increased fraud and inefficiency on the job, thus lessening competitiveness and hampering development.In this context, the present research examines 48 licenciatura theses and 102 masters theses from five of Mozambique’s largest universities. Of the 150 theses, 75% contained significant plagiarism (>100 word equivalents) and 39%, very much (>500 word equivalents). Significant plagiarism was detected in both licenciatura and masters (...) theses. By using both Turnitin and Urkund to identify potentially plagiarized passages, professionally verifying whether those passages contain plagiarism, and, if confirmed, counting the words involved, the study presents a new method for classifying the quantity and significance of plagiarism. The use of two text-similarity-recognition programs also improved the rate of detection and, in some theses, significantly increased the classification of the gravity of the plagiarism encountered.Based on a broad review of the literature, the article argues that, to combat wide-scale plagiarism, academic institutions need to cultivate a consensus among faculty and students about the definition and types of plagiarism, the appropriate penalties, and the paramount professional and economic need to nurture professional ethics. However, to achieve even partial success requires significant involvement by administrators, faculty, students and student leaders guided by a holistic strategy using technological, pedagogical, administrative and legal components to prevent and detect plagiarism and then reeducate or discipline students caught plagiarizing. (shrink)

An economic agenda, characterized by the mastery of subject knowledge or expertise, increasingly dominates higher education. In this article, I argue that this agenda fails to satisfy the full range of students’ aspirations, responsibilities and needs. Neither does it meet the needs of society. Rather, the overall purpose of higher education should be the morphogenesis of the agency of students, considered on an individual and on a collective basis. The article builds on recent critical realist theorizing to trace the generative (...) mechanisms that affect the morphogenesis of such agency. I argue that reflexive deliberation shapes the agency of students as they engage in teaching–learning interactions. It may be possible to enhance the agency of students if approaches are used that consider curricular knowledge, the presence of supportive social relations and the dedication of students. The article offers ways to promote the flourishing of students rather than their dehumanization. (shrink)

Byrne & Russon's notion of program-level imitation is based on the ability of apes to plan novel sequences of behavior and on how information gleaned by observation can aid the planning process. Byrne & Russon would have made a stronger case by focusing on social learning and planning and expending less effort interpreting their results as a new category of imitation.

Webb compares robots to other behavior models in a novel space, but neglects significant portions of this space. The article's analysis of models would have been strengthened by including a broader coverage of physically embodied models and of models of social behavior. Nevertheless, Webb is correct to claim that robot construction will contribute to understanding behavior.

It has been suggested that God can act on the world by operating within the limits set by Heisenberg's uncertainty principle (HUP) without violating the laws of nature. This requires nature to be intrinsically indeterministic. However, according to the statistical interpretation the quantum mechanical wavefunction represents the average behavior of an ensemble of similar systems and not that of a single system. The HUP thus refers to a relation between the spreads of possible values of position and momentum and so (...) is consistent with a fully deterministic world. This statistical interpretation of quantum mechanics is supported by reference to actual measurements, resolves the quantum paradoxes, and stimulates further research. If this interpretation is accepted, quantum mechanics is irrelevant to the question of God's action in the world. (shrink)

Publishing a collection of fragments from a classical author is a risky business: the moment the book appears in print, it may already be outdated, as new fragments could have come to light. Or, in the words of Ecclesiasticus 18:7: ‘When a man hath done, then he beginneth; and when he leaveth off, then he shall be doubtful’. The same fate befell me shortly after the publication of my collection of fragments from Rufus of Ephesus' On Melancholy. Manfred Ullmann wrote (...) to me that the late Rainer Degen had discovered a new fragment; in the course of my research, I came across some relevant quotations in the Hippocratic Treatments by the tenth-century author aṭ-Ṭabarī; and recently, Klaus-Dietrich Fischer published two related fragments. The following short note contains these new fragments together with an English translation and commentary. At the end, I also offer some addenda and corrigenda, partly in light of the reviews that have since appeared. (shrink)

Hippocrates is a towering figure in Greek medicine. Dubbed the 'father of medicine', he has inspired generations of physicians over millennia in both the East and West. Despite this, little is known about him, and scholars have long debated his relationship to the works attributed to him in the so-called 'Hippocratic Corpus', although it is undisputed that many of the works within it represent milestones in the development of Western medicine. In this Companion, an international team of authors introduces major (...) themes in Hippocratic studies, ranging from textual criticism and the 'Hippocratic question' to problems such as aetiology, physiology and nosology. Emphasis is given to the afterlife of Hippocrates from Late Antiquity to the modern period. Hippocrates had as much relevance in the fifth-century BC Greek world as in the medieval Islamic world, and he remains with us today in both medical and non-medical contexts. (shrink)

To understand the intracellular mechanisms that control exocytosis it is necessary to have access to the cell interior. This is achieved by plasma membrane permeabilisation or by application of patch‐pipettes. These conditions permit control over the cytosol composition and also allow leakage of soluble factors that may have roles in the exocytotic mechanism. Different permeabilisation methods allow different extents of leakage and therefore provide complementary data. The exocytotic machinery itself remains intact and can be activated by providing Ca2+ and/or a (...) guanine nucleotide. In some cells there is evidence for the participation of two guanine nucleotide‐binding proteins (Gp and GE), as well as a Ca2+ ‐binding protein. In others Ca2+ is the only requirement. In a number of cell types, ATP is not required for the late steps in the secretory pathway. (shrink)

Investigations into ethical judgments generally seem fuzzy as to the relevant research domain. We first attempted to clarify the construct and determine domain parameters. This attempt required addressing difficulties associated with pinpointing relevant literature, most notably the varied nomenclature used to refer to ethical judgments (individual evaluations of actions’ ethicality). Given this variation in construct nomenclature and the difficulties it presented in identifying pertinent focal studies, we elected to focus on research that cited papers featuring prominent and often-used measures of (...) ethical judgments (primarily, but not exclusively, the Multidimensional Ethics Scale). Our review of these studies indicated a preponderance of inferences and conclusions unwarranted by empirical evidence (likely attributable at least partly to inconsistent nomenclature). Moreover, ethical judgments related consistently to few respondent characteristics or any other variables, emergent relationships may not always be especially meaningful, and much research seems inclined to repetition of already verified findings. Although we concluded that knowledge about ethical judgments seems not to have advanced appreciably after decades of investigation, we suggested a possible path forward that focuses on the content of what is actually being judged as reflected in the myriad of vignettes used in the literature to elicit judgments. (shrink)