Epistemology has for a long time focused on the concept of knowledge and tried to answer questions such as whether knowledge is possible and how much of it there is. Often missing from this inquiry, however, is a discussion on the value of knowledge. In The Value of Knowledge and the Pursuit of Understanding Jonathan Kvanvig argues that epistemology properly conceived cannot ignore the question of the value of knowledge. He also questions one of the most fundamental assumptions in (...) epistemology, namely that knowledge is always more valuable than the value of its subparts. Taking Platos' Meno as a starting point of his discussion, Kvanvig tackles the different arguments about the value of knowledge and comes to the conclusion that knowledge is less valuable than generally assumed. Clearly written and well argued, this 2003 book will appeal to students and professionals in epistemology. (shrink)

Renowned moral philosopher Jonathan Glover confronts the brutal history of the twentieth century to unravel the mystery of why so many atrocities occurred. In a new preface, Glover brings the book through the post-September 11 era and into our own time—and asks whether humankind can "weaken the grip war has on us." _Praise for the first edition:_ “It is hard to imagine a more important book. Glover makes an overwhelming case for the need to understand our own inhumanity, and (...) reduce or eliminate the ways in which it can express itself—and he then begins the task himself. _Humanity _is_ _an extraordinary achievement.”—Peter Singer, Princeton University “This is an extraordinary book: brilliant, haunting and uniquely important. Almost 40 years ago a president read a best seller and avoided a holocaust. I like to think that some of the leaders and followers of tomorrow will read _Humanity._”_—_Steven Pinker, _New York Times Book Review_. (shrink)

Jonathan Walkan challenges cognitive science's dominant model of mental representation and proposes a novel, well-devised alternative. The traditional view in the cognitive sciences uses a linguistic model of mental representation. That logic-based model of cognition informs and constrains both the classical tradition of artificial intelligence and modeling in the connectionist tradition. It falls short, however, when confronted by the frame problem---the lack of a principled way to determine which features of a representation must be updated when new information becomes (...) available. So far, proposed alternatives, including the imagistic model, have not resolved the problem. Waskan proposes the Intrinsic Cognitive Models hypothesis, according to which representational states can be concpetualized as the cognitive equivalent of scale models.Waskan argues further that the proposal that humans harbor and manipulate cognitive counterparts to scale models offers the only viable explanation for what most clearly differentiates humans from other creatures: the capacity to engage in truth-preserving manipulation of representations. The ICM hypothesis, he claims, can be distinguished from sentence-based accounts of truth preservation in a way that is fully compatible with what is known about the brain. (shrink)

This book explores the idea that much of our behaviour is controlled by automatic and intuitive mental processes, which shape and compete with our conscious thinking and decision making. Accessibly written, and assuming no prior knowledge of the field, the book will be fascinating reading for all those interested in human behaviour.

The last two decades have witnessed a crescendo of allegations that clinical translation is rife with waste and inefficiency. Patient advocates argue that excessively demanding regulations delay access to life‐saving drugs, research funders claim that too much basic science languishes in academic laboratories, journal editors allege that biased reporting squanders public investment in biomedical research, and drug companies (and their critics) argue that far too much is expended in pharmaceutical development.But how should stakeholders evaluate the efficiency of translation and proposed (...) reforms to drug development? Effective reforms require an accurate model of the systems they aspire to improve—their components, their proper functions, and their pathologies. However, there is currently no explicit and well‐developed model of translation for evaluating such criticisms.In what follows, we offer an explicit model of clinical translation. Many discussions of clinical translation and its pathologies presume that its main output is tangible: new drugs, vaccines, devices, and diagnostics. We disagree. We argue that the principal output of clinical translation is information—in particular, information about the coordinated set of materials, practices, and constraints needed to safely unlock the therapeutic or preventive activities of drugs, biologics, and diagnostics. To develop this information calls for a process far different from a simple linear progression of clinical trials; it requires exploratory sampling of many different elements in this set. Our model points to some limitations and liabilities of influential proposals for reforming research. It also reveals some underrecognized opportunities for improving the efficiency of clinical translation. (shrink)

Experimental manipulations are a key means to establish causal relationships in microbiology. However, challenges remain to establish the applicability of such experiments beyond the precise conditions in which they were conducted. Ecological information can help address these challenges by describing the extent to which an experimentally-determined mechanism can explain the natural phenomenon that it is purported to cause.

How do our engagements with fictions and other products of the imagination compare to our experiences of the real world? Are the feelings we have about a novel's characters modelled on our thoughts about actual people? If it is wrong to feel pleasure over certain situations in real life, can it nonetheless be right to take pleasure in analogous scenarios represented in a fantasy or film? Should the desires we have for what goes on in a make-believe story cohere with (...) what we want to happen in the actual world? In Apt Imaginings, Jonathan Gilmore develops a new framework to pursue these questions, marshalling a wide range of research in aesthetics, the science of the emotions, moral philosophy, neuroscience, cognitive psychology, and film and literary theory. Gilmore argues that, while there is a substantial empirical continuity in our feelings across art and life, the norms that govern the appropriateness of those responses across the divide are discontinuous. In this view, the evaluative criteria that determine the fit, correctness, or rationality of our emotions and desires for what is internal to a fiction can be contrary to those that govern our affective attitudes toward analogous things in the real world. In short, it can be right to embrace within a story what one would condemn in real life. The theory Gilmore defends in this volume helps to explain our complex and sometimes conflicted attitudes toward works of the imagination; challenges the popular view that fictions serve to refine our moral sensibilities; and exposes a kind of autonomy of the imagination that can render our responses to art immune to standard real-world epistemic, practical, and affective kinds of criticism. (shrink)

Bootstrapping is a suspicious form of reasoning that verifies a source's reliability by checking it against itself. Theories that endorse such reasoning face the bootstrapping problem. This article considers which theories face the problem, and surveys potential solutions. The initial focus is on theories like reliabilism and dogmatism, which allow one to gain knowledge from a source without knowing that it is reliable. But the discussion quickly turns to a more general version of the problem that does not depend on (...) this allowance. Five potential solutions to the general problem are evaluated, and some implications for the literature on peer disagreement are considered. (shrink)

For some time, it seemed that one had to choose between two sharply different theories of epistemic justification, foundationalism and coherentism. Foundationalists typically held that some beliefs were certain, and, hence, basic. Basic beliefs could impart justification to other, non-basic beliefs, but needed no such support themselves. Coherentists denied that there are any basic beliefs; on their view, all justified beliefs require support from other beliefs. The divide between foundationalism and coherentism has narrowed lately, and Susan Haack attempts to synthesize (...) these competing accounts into a view she calls "foundherentism.". (shrink)

Properties come in clusters. It seems impossible, for instance, that a mass could float free, unattached to any other property. David Armstrong takes this as a reductio of the bundle theory and an argument for substrata, while Peter Simons and Arda Denkel reply by supplementing the bundle theory with accounts of property interdependencies. I argue against both views. Virtually all plausible ontologies turn out to be committed to the existence of free masses. I develop and defend the view that the (...) clustering of properties is a mere contingent truth, on grounds that properties can be subtracted one‐by‐one. This opens the door not just to the (unsupplemented) bundle theory, but also to any plausible account of the relation between objects and properties. (shrink)

I start with a brief look at what the classic British intuitionists (Ewing, Broad, Ross) had to say about the relation between judgment and emotion. I then look at some more recent work in the intuitionist tradition and try to develop a conception of moral emotion as a form of practical seeming, suggesting that some moral intuitions are exactly that sort of emotion. My general theme is that the standard contrast between intuition and emotion is a mistake and that intuitionism (...) can happily accommodate the results of recent work in empirical moral psychology. (shrink)

abstract The most well‐known liberal‐egalitarian defence of cultural rights, provided by Will Kymlicka, presents culture as a primary good, and thus a resource that ought to be distributed according to some fair egalitarian criteria. Kymlicka relies on the intuition that inequalities between persons that are the result of brute luck rather than personal choice are unjust in making the case for various multicultural rights. This article makes two main claims. First, the standard luck egalitarian intuition on which Kymlicka's argument relies (...) cannot justify what he calls ‘polyethnic rights,’ in particular cultural and religious exemptions from generally applicable laws. Second, I argue that such exemptions are justifiable by appealing to the public value of fair equality of opportunity, properly construed. (shrink)

This article makes four claims. First, that the analytic/Continental split in political theory stems from an unarticulated disagreement about human nature, with analytics believing we have an innate set of mostly compatible moral and political inclinations, and Continentals seeing such things as alterable products of historical contingency. Second, that we would do better to talk of Continental-political-theory versus Rawlsian-political-philosophy, given that the former avoids arguments over principles, whilst the latter leaves genuine analytic philosophy behind. Third, that Continentals suffer from a (...) lack of such arguments, even by their own lights, whilst Rawlsians suffer from inconsistencies within the thought-patterns on which their principles depend. Fourth, that there is an alternative method – ‘normative behaviourism’ – that at least tries to move beyond the problems of both approaches, whilst sharing an idea of ‘praxis’ with the first, and an idea of deriving-principles-from-existing-judgements with the second. (shrink)

Jonathan Dancy; I *—The Presidential Address: Why there is really No Such Thing as the Theory of Motivation, Proceedings of the Aristotelian Society, Volume 95.

Many commentators have expressed concern that large investments in biomedical research over the past two decades have not been translated effectively into clinical applications. In its Critical Path Report, the Food and Drug Administration characterized the problem as a “technological disconnect between discovery and the product development process,” and documented that the number of investigational new drugs submitted to the agency had declined “significantly” since 2000. Along a similar vein, another study found that only five of 101 basic science studies (...) showing significant therapeutic promise were successfully translated into clinical applications.This perceived translational lag is stimulating a shift toward human testing of study interventions earlier in the drug development process. One indication of this trend is a recent guidance encouraging sponsors to pursue human “exploratory” studies before embarking on phase I trials. (shrink)

This article examines the factors that influence the propensity of corporations to engage with NGOs. Drawing from resource dependency theory and related theories of social networks and the resource-based view of the firm, the authors develop a series of hypotheses that draw from this conceptual foundation to predict a range of factors that influence firms to collaborate with NGOs. These factors include the level of commitment of the firm to CSR, the strategic fit between the firm’s and the NGO’s resources, (...) the level of trust the firm has in NGOs, the frequency of contact with NGOs, prior level and perception of experience with NGOs, and the level of pressure exerted by NGOs. The authors report on results of a survey of the Top 500 firms in the Netherlands on their interactions with NGOs, finding general support for our hypotheses, and suggest that understanding the motives for firm–NGO interactions can teach us more about firms’ corporate social activities and the way such activities are shaped in the dynamic interplay between firms and their stakeholders. Our findings are relevant for future research on cross-sectoral interactions, for corporations considering future relationships with NGO cohorts, and for broader questions about the role of stakeholders and the role of business in society. (shrink)

Jonathan Bennett's analysis of the second half of Kant's Critique of Pure Reason, in which Kant concerns himself with topics such as substance, the nature of the self, the cosmos, freedom and the existence of God, continues to be an engaging and accessible exploration of Kant's major work. Presented in a fresh twenty-first-century series livery, and including a specially commissioned preface written by Karl Ameriks, illuminating its enduring importance and relevance to philosophical enquiry, this influential work has been revived (...) for a new generation of readers. (shrink)

The Food and Drug Administration and the European Agency for the Evaluation of Medicinal Products recently issued documents encouraging sponsors to consider microdose testing before launching Phase I trials, and many commentators predict that such methodologies will be applied more routinely in drug development. However, exploratory testing has provoked several ethical criticisms. Skeptics question the value and validity of microdose trials, and whether they present a reasonable balance of risks and benefits for subjects. Another major criticism is that such studies (...) serve mainly commercial ends. The present article explores these and other ethical concerns for studies conducted in the oncology setting. It concludes that microdosing is not inconsistent with prevailing practices in Phase I research, and that in principle, such studies could strengthen the ethical basis for Phase I trials by providing them better evidentiary justification. (shrink)

This book provides the first systematic, book-length defence of natural law ideas in ethics, politics and jurisprudence since John Finnis's influential Natural Law and Natural Rights. Incorporating insights from recent work in ethical, legal and social theory, it presents a robust and original account of the natural law tradition, challenging common perceptions of natural law as a set of timeless standards imposed on humans from above. Natural law, Jonathan Crowe argues, is objective and normative, but nonetheless historically extended, socially (...) embodied and dependent on contingent facts about human nature. It reflects the ongoing human quest to work out how best to live flourishing lives, given the natures we have and the social environments we inhabit. The nature and purpose of law can only be adequately understood within this wider context of value. Timely, wide-ranging and clearly written, this volume will appeal to those working in law, philosophy and religious studies. (shrink)

"To some people, life is very simple . . . no shadings and grays, all blacks and whites. . . . Now, others of us find that good, bad, right, wrong, are many-sided, complex things. We try to see every side; but the more we see, the less sure we are." —Sir John Talbot, The Wolf Man (Universal Pictures, 1941).

Devotion is the defining religious practice and central theological concept of the Gauḍīya Vaiṣṇava tradition, and this article is about the catalytic event that is said to instigate bhakti in the non-devoted. I examine how Jīva Gosvāmin and Viśvanātha Cakravartin, two important theologians in this tradition, argue that the cause of bhakti in the non-devoted is a meeting with a devotee. In this meeting, the non-devoted may develop conviction, which in turn gives him or her the motivation to continue along (...) the path of bhakti, the steps of which were charted in the Bhaktirasāmṛtasindhu of Rūpa Gosvāmin. Based on a few key passages from the Gauḍīya’s primary scriptural source, the Bhāgavata Purāṇa, Jīva and Viśvanātha argue that this conviction for bhakti is developed spontaneously. Since the spontaneous conviction to practice bhakti can only occur in sādhu-saṅga, or a meeting with a devotee, what causes that meeting? The devotee always acts freely and independently ; thus his or her motivation to meet and inspire conviction in the non-devoted is not reducible to a divine plan, divine grace, the piety of the receiver, special features of the receiver’s soul, high birth, or any other designation. Rather, the cause of sādhu-saṅga is the bhakti “living in the heart” of a devotee. This bhakti makes the devotee feel compassion toward the non-devoted, which leads him or her to provide sādhu-saṅga, which then creates conviction, which eventually leads to bhakti. (shrink)

This essay contends that while Nancy and Esposito have strikingly similar concepts of the place of the political in post-metaphysical community, their respective articulations of these concepts noticeably diverge. Because of his commitment to excavating the political project of immunity as central to the Western political tradition in and through the category of the legal person, Esposito announces community as impolitical, as the interruptive spacing, and thus alternating displacement, of the political conceived as the site of emancipatory agency. In contrast, (...) in the work of Agamben and in the recent work of Nancy, an articulation of the person and the political in more agential terms can be found. This divergence presents interpretive difficulties insofar as Esposito's discussion of community as impolitical could be read as advancing ontological neutrality or passivity that threatens to separate political activity from its liberating potential. I argue that such ontological neutrality is a product of Esposito's confrontation with the political as dominated by both the logic of immunity and an engagement with the complex legacy of Heidegger's problematic political trajectory. To this extent it is an open question whether Esposito's project leaves room for a new vision of the political and for political agency. (shrink)

“Busyness” plainly relates to externally observable work or leisure activities, but nevertheless the state itself is entirely subjective. I will argue in what follows, that there may have been fundamental changes in the connection between the external circumstances of work and leisure and internal feelings of “busyness”. Through the last century there have been fundamental shifts in the relationship between the pattern of daily activities, and patterns of societal sub- and superordination. “Are you busy?” may have had a quite different (...) meaning as addressed to an upwardly mobile member of the Victorian English or American middle classes, as compared to an office worker at the turn of the third millennium. Individuals’ representations of their states of “busyness” play an important, and changing, role in establishing their positions in the order of social stratification. A leisure class at the end of the 19th century perhaps, but the dominant groups in the early 21st are in the most straightforward sense of the word, workers. I will suggest that, reflecting this fundamental shift in social structure, the social construction of “busyness” has also changed. (shrink)

Matching bias in conditional reasoning consists of a tendency to select as relevant cases whose lexical content matches that referred to in the conditional statement, regardless of the presence of negatives. Evans demonstrated that use of explicit rather than implicit negative cases markedly reduced the matching bias effect on the conditional truth table task. In apparent contrast, recent studies of explicit negation on the Wason selection task have failed to find evidence of logical facilitation. Experiment 1 of the present study (...) strongly replicated the Evans findings and extended them to three forms of conditional statement. Experiments 2 and 3 showed further that the use of explicit negatives removed completely the matching bias effect on the Wason selection task. However, consistent with other recent studies, this elimination of bias didnotlead to facilitation of correct responding. The findings are interpreted as providing evidence that matching bias reflects a linguistically cued relevance effect. (shrink)

In a recent article in this journal, Schaefer et al. argue that it might be possible to enhance autonomy through the use of cognitive enhancements. In this article, I highlight an example that Schaefer et al. do not acknowledge of a way in which we already seem to be using pharmacological agents in a manner that can be understood as enhancing an agent’s autonomy. To make this argument, I begin by following other theorists in the philosophical literature in claiming that (...) impulsivity can serve to undermine an agent’s autonomy. I then explain that we are already able to reduce impulsivity through the use of pharmacological interventions, as is evidenced by the use of Methylphenidate in the treatment of ADHD. (shrink)

A unique response to the challenging questions raised in the science and religion dialogue by drawing on Hindu theology. Edelmann replies to the sciences through close reading of an important Hindu text, the Bhāgavata Puraṇa, as well engaging with Hindu philosophical disciplines such as Saṁkhya-Yoga.

Although The Origin of Species contained just a single visual illustration, Charles Darwin's other books, from his monograph on barnacles in the early 1850s to his volume on earthworms in 1881, were copiously illustrated by well-known artists and engravers. In this 2006 book, Jonathan Smith explains how Darwin managed to illustrate the unillustratable - his theories of natural selection - by manipulating and modifying the visual conventions of natural history, using images to support the claims made in his texts. (...) Moreover, Smith looks outward to analyse the relationships between Darwin's illustrations and Victorian visual culture, especially the late-Victorian debates about aesthetics, and shows how Darwin's evolutionary explanation of beauty, based on his observations of colour and the visual in nature, were a direct challenge to the aesthetics of John Ruskin. The many illustrations reproduced here enhance this fascinating study of a little known aspect of Darwin's lasting influence on literature, art and culture. (shrink)

I defend contextualist solutions to the sorites paradox (according to which solutions vague terms are indexicals) from a recent objection raised by Jason Stanley. Stanley's argument depends on the claim that indexical expressions always have invariant interpretations in "Verb Phrase" ellipsis. I argue that this claim is false.

I start by examining Robert Audi's positive suggestions about moral perception, and then attempt to point out some challengeable assumptions that he seems to make, and to consider how things might look if those assumptions are abandoned.

A well-established phenomenon in reasoning research is matching bias : a tendency to select information that matches the lexical content of propositional statements, regardless of the logically critical presence of negations. Previous research suggested, however, that the effect might be restricted to reasoning with conditional statements. This paper reports two experiments in which participants were required to construct or identify true and false cases of propositional rules of several kinds, including universal statements, disjunctions, and negated conjunctions. Matching bias was observed (...) across all rule types but largely restricted to problems where participants were required to falsify rather than to verify the rules. A third experiment showed a similar generalization across linguistic forms in the Wason selection task with only if conditionals substituted for universals. The results are discussed with reference to contemporary theories of propositional reasoning. (shrink)

A recurring question about cost - benefit analysis concerns its scope. CBA is a decision-making method frequently employed in environmental policy-making, in which things which have no market price are treated as if they were commodities. They are given a monetary value, a form of price. But it is widely held that some things cannot be meaningfully priced, thus substantially limiting the scope of CBA. The aim of this paper is to test some aspects of this broad claim, focusing on (...) problems of incomparability and incommensurability. In particular, the role of rough equality as a putative form of comparison is investigated. I argue that while an assessment of the full significance of rough equality for practical decision-making awaits resolution of a number of important technical questions, it does not provide a strong enough form of comparison to support CBA. (shrink)