This article is the lead piece in a special report that presents the results of a bioethical investigation into chimeric research, which involves the insertion of human cells into nonhuman animals and nonhuman animal embryos, including into their brains. Rapid scientific developments in this field may advance knowledge and could lead to new therapies for humans. They also reveal the conceptual, ethical, and procedural limitations of existing ethics guidance for human‐nonhuman chimeric research. Led by bioethics researchers working closely with an (...) interdisciplinary work group, the investigation focused on generating conceptual clarity and identifying improvements to governance approaches, with the goal of helping scholars, funders, scientists, institutional leaders, and oversight bodies (embryonic stem cell research oversight [ESCRO] committees and institutional animal care and use committees [IACUCs]) deliver principled and trustworthy oversight of this area of science. The article, which focuses on human‐nonhuman animal chimeric research that is stem cell based, identifies key ethical issues in and offers ten recommendations regarding the ethics and oversight of this research. Turning from bioethics’ previous focus on human‐centered questions about the ethics of “humanization” and this research's potential impact on concepts like human dignity, this article emphasizes the importance of nonhuman animal welfare concerns in chimeric research and argues for less‐siloed governance and oversight and more‐comprehensive public communication. (shrink)

Additional Contributors Include John V. Walsh, Bruno De Solages, Aurel Kolnai, Gabriel Marcel, Michele Federico Sciacca, Henri De Lubac, Robert W. Gleason, And Jacques Albert Cuttat. The Orestes Brownson Series On Contemporary Thoughts And Affairs, No. 3.

Additional Contributors Include John V. Walsh, Bruno De Solages, Aurel Kolnai, Gabriel Marcel, Michele Federico Sciacca, Henri De Lubac, Robert W. Gleason, And Jacques Albert Cuttat. The Orestes Brownson Series On Contemporary Thoughts And Affairs, No. 3.

A remarkable collection of interviews and dialogues that discuss culture, ideology, history, Marxism, modernity, post-modernity, post-colonialism, globalization, and the role of the university and the intellectual in today's society.

Rational agents are supposed to maximize expected utility. But what are the options from which they choose? I outline some constraints on an adequate representation of an agent’s options. The options should, for example, contain no information of which the agent is unsure. But they should be sufficiently rich to distinguish all available acts from one another. These demands often come into conflict, so that there seems to be no adequate representation of the options at all. After reviewing existing proposals (...) for how to construe decision-theoretic options and finding them all wanting, I suggest that our model of rational agents should include a special domain of ‘virtual’ option propositions to serve as formal objects of deliberation and choice. (shrink)

Some cognitive processes appear to have “phenomenal” properties that are directly revealed to the subject and not determined by physical properties. I suggest that the source of this appearance is the method by which our brain processes sensory information. The appearance is an illusion. Nonetheless, we are not mistaken when we judge that people sometimes fee lpain.

"L'oeuvre d'art est une tentative vers l'unique, elle s'affirme comme un tout, comme un absolu et, en même temps, elle appartient à un système de relations complexes [...]. Elle est matière et elle est esprit, elle est forme et elle est contenu [...]. Elle est créatrice de l'homme, créatrice du monde et elle installe dans l'histoire un ordre qui ne se réduit à rien d'autre." Un Eloge de la main complète ce texte. "La main arrache le toucher à sa passivité (...) réceptive, elle l'organise pour l'expérience et pour l'action [...]. Elle se mesure avec la matière qu'elle métamorphose, avec la forme qu'elle transfigure. Educatrice de l'homme, elle le multiplie dans l'espace et dans le temps." [Source : 4e de couv.]. (shrink)

Magnetism in meta-semantics is the view that the meaning of our words is determined in part by their use and in part by the objective naturalness of candidate meanings. This hypothesis is commonly attributed to David Lewis, and has been put to philosophical work by Brian Weatherson, Ted Sider and others. I argue that there is no evidence that Lewis ever endorsed the view, and that his actual account of language reveals good reasons against it.

Our senses provide us with information about the world, but what exactly do they tell us? I argue that in order to optimally respond to sensory stimulations, an agent’s doxastic space may have an extra, “imaginary” dimension of possibility; perceptual experiences confer certainty on propositions in this dimension. To some extent, the resulting picture vindicates the old-fashioned empiricist idea that all empirical knowledge is based on a solid foundation of sense-datum propositions, but it avoids most of the problems traditionally associated (...) with that idea. The proposal might also explain why experiences appear to have a non-physical phenomenal character, even if the world is entirely physical. (shrink)

Intelligence on mass media audiences was founded on representative statistical samples, analysed by statisticians at the market departments of media corporations. The techniques for aggregating user data in the age of pervasive and ubiquitous personal media build on large aggregates of information analysed by algorithms that transform data into commodities. While the former technologies were built on socio-economic variables such as age, gender, ethnicity, education, media preferences, Big Data technologies register consumer choice, geographical position, web movement, and behavioural information in (...) technologically complex ways that for most lay people are too abstract to appreciate the full consequences of. The data mined for pattern recognition privileges relational rather than demographic qualities. We argue that the agency of interpretation at the bottom of market decisions within media companies nevertheless introduces a ‘heuristics of the algorithm’, where the data inevitably becomes translated into social categories. In the paper we argue that although the promise of algorithmically generated data is often implemented in automated systems where human agency gets increasingly distanced from the data collected, one can observe a felt need among media users and among industry actors to ‘translate back’ the algorithmically produced relational statistics into ‘traditional’ social parameters. The tenacious social structures within the advertising industries work against the techno-economically driven tendencies within the Big Data economy. (shrink)

This paper starts out from the idea that semantics is a “special science” whose aim, like that of chemistry or ecology, is to identify systematic, high-level patterns in a fundamentally physical world. I defend an approach to this task on which sentences are associated with with sets of possible worlds (of some kind). These sets of worlds, however, are not postulated for the compositional treatment of intensional contexts; they are not meant to capture what is intuitively asserted or communicated by (...) an utterance; nor are they supposed to shed light on the cognitive processes that underlie out linguistic competence. Instead, their job description is to capture certain regularities in the interactions between subjects using the relevant language. I also raise some questions about how the relevant worlds might be construed. (shrink)

Modal accounts of knowledge, mind, and language, as prominently defended by Lewis, leave no room for enquiry into non-contingent matters. According to Lewis, there is only one necessarily true proposition, and it is vacuously known by everyone. What, then, are we doing when we do metaphysics, which often seems to deal with non-contingent questions? Lewis never gave a satisfactory answer, or even acknowledged the problem. I explore some options. Can we understand the relevant parts of metaphysics as dealing with contingent (...) questions about our concepts? Can we understand them in terms of a hyperintensional conception of “explicit” knowledge? Both options have some promise. Ultimately, however, I don’t think they succeed at squaring Lewis’s empiricist epistemology with his metaphysical realism. (shrink)

"With its signal distinction between 'intuition' and 'analysis' and its exploration of the different levels of Duration, _An Introduction to Metaphysics_ has had a significant impact on subsequent twentieth century thought. The arts, from post-impressionist painting to the stream of consciousness novel, and philosophies as diverse as pragmatism, process philosophy, and existentialism bear its imprint. Consigned for a while to the margins of philosophy, Bergson’s thought is making its way back to the mainstream. The reissue of this important work comes (...) at an opportune time, and will be welcomed by teachers and scholars alike." --Peter A. Y. Gunter, University of North Texas. (shrink)

Possible-worlds accounts of mental or linguistic content are often criticized for being too coarse-grained. To make room for more fine-grained distinctions among contents, several authors have recently proposed extending the space of possible worlds by "impossible worlds". We argue that this strategy comes with serious costs: we would effectively have to abandon most of the features that make the possible-worlds framework attractive. More generally, we argue that while there are intuitive and theoretical considerations against overly coarse-grained notions of content, the (...) same kinds of considerations also prohibit an overly fine-grained individuation of content. An adequate notion of content, it seems, should have intermediate granularity. However, it is hard to construe a notion of content that meets these demands. Any notion of content, we suggest, must be either implausibly coarse-grained or implausibly fine-grained (or both). (shrink)

A tribute to vision boards evaluates their creative, motivational, and inspirational role in providing visual life and career maps for famous and everyday ...

Bringing together evolutionary biology, psychology, and philosophy, Henry Plotkin presents a new science of knowledge, one that traces an unbreakable link between instinct and our ability to know.

In Listening Subjects, David Schwarz uses psychoanalytic techniques to probe the visceral experiences of music listeners.

A monumental work by an important modern philosopher, Matter and Memory (1896) represents one of the great inquiries into perception and memory, movement and time, matter and mind. Nobel Prize-winner Henri Bergson surveys these independent but related spheres, exploring the connection of mind and body to individual freedom of choice. Bergson’s efforts to reconcile the facts of biology to a theory of consciousness offered a challenge to the mechanistic view of nature, and his original and innovative views exercised a profound (...) influence on other philosophers--including James, Whitehead, and Santayana--as well as novelists such as Dos Passos and Proust. Matter and Memory is essential to an understanding of Bergson’s philosophy and its legacy. (shrink)

Als Charles Darwin im Jahr 1859 seine Theorie einer Evolution der Arten durch natürliche Auslese veröffentlichte, sah er bereits eine grosse Debatte voraus, jedoch nicht deren Ausstrahlungskraft und Langlebigkeit. Zu Beginn standen die Folgen für die Wissenschaften, den Glauben an Gott und die Moralvorstellungen im Vordergrund. Bald kamen Überlegungen über Gesellschaft, Politik, internationale Beziehungen und über Eingriffe bis hinunter auf die Ebene des Individuums und seines Erbmaterials, seiner Gene hinzu. Sozialdarwinismus, Eugenik, Rassismus galten zeitweise als wissenschaftlich legitime Diskussions- und Politikfelder. (...) Befürchtungen vor einem vermeintlichen Niedergang lassen sich bis heute angesichts der Biologisierung des Denkens scheinbar wissenschaftlich-objektiv untermauern. Gegenwärtig sind die Kontroversen noch vielfältiger, beziehen weit mehr Menschen ein als im späten 19. Jahrhundert, haben weit gravierendere Auswirkungen. Die aus elf Ländern stammenden Autorinnen und Autoren zeichnen aus unterschiedlichen disziplinären Perspektiven die Facetten einer spannenden und bis in die Gegenwart hochaktuellen Debatte nach und fragen nach der Zukunft des "Streitfalls Evolution". (shrink)

Giroux argues that challenge gives new meaning to the importance of resistance, the relevance of pedagogy, and the significance of political agency.

This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work. This work is in the public domain (...) in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant. (shrink)

Dichotomous categories, such as the West and the rest, primitive and modern, are discussed within a phenomenological theory that suggests humans create structures through which we perceive objects. The perception of culture as an object and its construction through the epistemological practices of fieldwork and interpretation within the metaphor of West and non-Western reveals the structure of sociocultural anthropological inquiry and expresses embodiment of the cosmology of nations. Experiences of, and shared understandings regarding, the body, soul, knowledge, thoughts, emotions, memories, (...) spirits, voice, and speech are compared from descriptions, participant observation, and embodiment as a multi-site ethnographic performance artist expressing new genres of ethnography. Harmony is defined as social location. (shrink)

Both an ideal entrée for beginning readers and a solid text for scholars, the second edition of Peter Kalkavage's acclaimed translation of Plato's _Timaeus_ brings enhanced accessibility to a rendering well known for its faithfulness to the original text. An extensive essay offers insights into the reading of the work, the nature of Platonic dialogue, and the cultural background of the _Timaeus_. Appendices on music, astronomy, and geometry provide additional guidance. A brief outline of the themes of the work, a (...) detailed glossary, and a selected bibliography are also included. (shrink)

This paper presents three experimental studies investigating the processing of presupposed content. The first two experiments employ the German additive particle auch ‘too’, and the third uses English also. In experiment 1, participants were given a questionnaire containing biclausal, ambiguous sentences containing auch. The presupposition introduced by auch was only satisfied on one of the two readings, which corresponded to a syntactically dispreferred parse of the sentence. The prospect of having the auch presupposition satisfied made participants choose this syntactically dispreferred (...) reading more frequently than in a control condition. Experiment 2 used the self-paced reading paradigm and compared the reading times on clauses containing auch, which differed in whether the presupposition of auch was satisfied or not. Participants read the clause more slowly when the presupposition was not satisfied. Experiment 3 followed up a number of issues that arose from experiment 2 and confirmed the results found there. These studies show that presuppositions play an important role in online sentence comprehension and affect the choice of syntactic analysis. Some theoretical implications of these findings for the semantic analysis of auch / also and dynamic accounts of presuppositions as well as for theories of semantic processing are discussed. (shrink)

It is argued that the principles of classical physics are inimical to the development of a satisfactory science of consciousness The problem is that insofar as the classical principles are valid consciousness can have no e ect on the behavior and hence on the survival prospects of the organisms in which it inheres Thus within the classical framework it is not possible to explain in natural terms the development of consciousness to the high level form found in human beings In (...) quantum theory on the other hand consciousness can be dynamically e cacious quantum the ory does allows consciousness to in uence behavior and thence to evolve in accordance with the principles of natural selection However this evo lutionary requirement places important constraints upon the details of the formulation of the quantum dynamical principles.. (shrink)

For the past 30 years, Paget Henry has been one of the most articulate and creative voices in Caribbean scholarship, making seminal contributions to the study of Caribbean political economy, C.L.R. James studies, critical theory, phenomenology, and Africana philosophy. This volume includes some of his most important essays from across his remarkable career, providing an introduction to a broad range of pressing contemporary themes and to the unique mind of one of the leading Caribbean intellectuals of his generation.