Graphical AbstractNowadays, in the Internet databases era, certain knowledge is being progressively lost. This knowledge, which we feel is essential and should be acquired through education, is the understanding of how the pioneer researchers faced major questions in their field and made their discoveries.

Small GTPases in the Rho family act as major nodes with functions beyond cytoskeletal rearrangements shaping the Caenorhabditis elegans embryo during development. These small GTPases are key signal transducers that integrate diverse developmental signals to produce a coordinated response in the cell. In C. elegans, the best studied members of these highly conserved Rho family small GTPases, RHO‐1/RhoA, CED‐10/Rac, and CDC‐42, are crucial in several cellular processes dealing with cytoskeletal reorganization. In this review, we update the functions described for the (...) Rho family small GTPases in spindle orientation and cell division, engulfment, and cellular movements during C. elegans embryogenesis, focusing on the Rho subfamily Rac.Please also see the video abstract here. (shrink)

The aim of the present study is to analyze individual differences in academic self-efficacy within a population of Unaccompanied Foreign Minors from the European cities of Ceuta and Melilla. Variables describing educational level and length of stay were considered in a sample of 377 individuals being cared for in different youth centers. Of these, 63.4% belonged to the group who had stayed at the center for less than 9 months and 36.6% reported a length of stay of more than 9 (...) months. The age of participants ranged between 8 and 17 years old. Once the quality parameters of the instrument were elaborated, reliability and validity was confirmed through Confirmatory Factor Analysis using Structural Equation Modeling methodology. Data collection was then initiated. The results overall indicate that 87.6% of those who completed the questionnaire reported a higher level of self-efficacy with regards to working with any classmate, whilst at the same time seeing themselves as capable of achieving good marks. ANOVA results indicated significant differences with respect to educational level and length of stay. In this regard, students who had received professional training and had been at the Center for more than 9 months, were the ones who developed greater academic self-efficacy for spending more time working when tasks were judged to be difficult. The results obtained demonstrate that any intervention will be positive as long as it promotes different institutions to develop strategies that cater to a length of stay of more than 9 months and target education, academic self-efficacy, socialization and strengthening the future workforce. Such interventions can be directed through new European, Spanish or local level policies. It is clear that institutions still have a lot of work left to do. (shrink)

Based on the results obtained from primary education students—fifth and sixth graders—the aim of this work is to check the appropriate self-perceived behaviors during and at the end of the game. The study population was made up of 698 students from fifth and sixth grade in the Autonomous Region of Castilla–La Mancha (Spain). Data were collected through a questionnaire (scale) on the social skills of primary school students linked to the adequate skills when losing, the adequate skills when winning, and (...) the adequate skills during the game. Study results revealed that analyzed behaviors vary, depending on the moment of the game, being it more frequently during the development of the game than when losing or winning. (shrink)

Introduction: Physical distancing under the coronavirus disease 2019 pandemic had a significant impact on lifestyles, including exercise routines. In this study, we examined the relationship between mental health and addictive behaviors, such as excessive exercise and the use of image and performance enhancing drugs across 12 sport disciplines.Materials and methods: A large cross-sectional sample of the adult population was surveyed. The mean age was 33.09. The number of male participants was 668. The use of IPEDs was assessed in conjunction with (...) psychometric measures such as the Exercise Addiction Inventory and the Appearance Anxiety Inventory. The participants were grouped into activity group and non-activity group according to the presence or absence of their exercise habits. The results were compared between these groups, as well as across sport disciplines, while taking into account the relationship between different psychological measures and IPEDs consumption.Results: The frequency of IPEDs use was higher among AG than NAG, although AG participants reported less history of addictions than NAG. The logistic regression analysis revealed that scores equal to or above cutoff points, in both the EAI and AAI, predicted the IPEDs use. Regarding the differences across the various sport disciplines, those who were involved in practicing Weight Lifting and Cross Fit were found to be more at risk of excessive exercising and more inclined to use a wide range of IPEDs.Conclusions: Although exercise could help to increase well-being and prevent addictions during the COVID-19 pandemic, our results show that those in the AG are particularly vulnerable to excessive IPEDs use. Sport disciplines associated with higher EAI and AAI scores have also shown a higher tendency to excessive IPEDs use. Furthermore, the factor of having above the cutoff scores in EAI or AAI in each sport could indicate larger IPEDs consumption regardless of the discipline. In light of the current findings, it is necessary to better define the “non-excessive” levels of exercise in various sport disciplines and an adequate intake of IPEDs to ensure the safety and well-being of people during a pandemic. (shrink)

Delusions are one of the most classical symptoms described in schizophrenia. However, despite delusions are often emotionally charged, they have been investigated using tasks involving non-affective material, such as the Beads task. In this study we compared 30 patients with schizophrenia experiencing delusions with 32 matched controls in their pattern of responses to two versions of the Beads task within a Bayesian framework. The two versions of the Beads task consisted of one emotional and one neutral, both with ratios of (...) beads of 60:40 and 80:20, considered, respectively, as the “difficult” and “easy” variants of the task. Results indicate that patients showed a greater deviation from the normative model, especially in the 60:40 ratio, suggesting that more inaccurate probability estimations are more likely to occur under uncertainty conditions. Additionally, both patients and controls showed a greater deviation in the emotional version of the task, providing evidence of a reasoning bias modulated by the content of the stimuli. Finally, a positive correlation between patients’ deviation and delusional symptomatology was found. Impairments in the 60:40 ratio with emotional content was related to the amount of disruption in life caused by delusions. These results contribute to the understanding of how cognitive mechanisms interact with characteristics of the task in the context of delusional thinking. These findings might be used to inform improved intervention programs in the domain of inferential reasoning. (shrink)

Die Ausführungen zum Begriff der Liebe in Hegels Ästhetik lassen sich als Spuren der Auseinandersetzung Hegels mit der Vereinigungsphilosophie lesen. Nach der These dieses Aufsatzes enthält die Ästhetik diese Spuren also noch, obgleich Hegels Abschied von der Vereinigungsphilosophie längst vollzogen war, als die Vorlesungen zur Ästhetik entstanden sind. Die Begriffe Philosophie der Vereinigung und Vereinigungsphilosophie bezeichnen Positionen in der Philosophie des 18. Jahrhunderts, die sich mit der Selbstwerdung des Subjekts oder des Bewußtseins befassen und mit der für die Selbstwerdung erforderlichen (...) Hingabe an ein Äußeres, Anderes. Infolge der Hingabe an ein Äußeres, Anderes werden dem Selbst die Grenzen und der Grund seines Selbst bewußt. Das Selbst benötigt demnach das Andere, um zu sich selbst zu kommen. Die Hingabe an das Endliche außer uns, die erforderlich ist, um in Abgrenzung zum Anderen zu einem Selbst zu werden, wird als Liebe im Sinne des Eros bestimmt. Diese Liebe ist der Antrieb, die Vereinigung mit dem Erstrebten zu suchen und die Erkenntnis des Wahren zu fin Für die Selbstwerdung oder Selbsterkenntnis werden dabei, je nach philosophischer Konzeption, unterschiedliche Bereiche als Ort der Vereinigung angenommen: Der Bereich der Religion, der auf die Erkenntnis Gottes und der Seele abhebt, die nur in der Wiedervereinigung der Seele mit Gott im Jenseits zu erlangen ist. Oder der Bereich des Schönen, der für Hölderlins Philosophie der Vereinigung zentral ist. Die allen Formen der Vereinigungsphilosophie zugrundeliegende Frage ist die nach dem Verhältnis zwischen dem Selbst (oder der Seele) und dem Begehrten, das zur Selbstwerdung gebraucht wird. Das Projekt der Selbstwerdung stellt aber nicht nur das erklärte Anliegen der Vereinigungsphilosophie dar, sondern auch das der romantischen Kunst, die, so Hegel, zur reinen unendlichen Identität mit sich selbst führt und nur noch einen Gott, einen Geist, eine absolute Selbstständigkeit kennt. Es ist für diese Periode nach Hegel geradezu die Aufgabe der Kunst, den Prozeß hin zur Subjektivität darzustellen. (shrink)

Das Archiv steht hoch im Kurs. Sowohl als Schauplatz theoretischer Auseinandersetzungen als auch als Gegenstand archivwissenschaftlicher Reflexionen und Neubewertungen bietet es unterschiedliche philosophische, kultur- und archivwissenschaftliche Zugänge, die miteinander korrespondieren oder sich in expliziten Widerspruch zueinander stellen. Was die philosophisch-kulturwissenschaftlichen und die archivwissenschaftlichen Zugänge jedoch verbindet, sind die Fragen nach den Gesetzmäßigkeiten, nach den Zuordnungen und den Vergegenwärtigungen, die im Archiv stattfinden und im Archiv ihren Ort haben. Der Parcours durch die unterschiedlichen Archiv-Konzeptionen, der in diesem Aufsatz unternommen wird, fokussiert (...) auf eben diese Fragestellungen, die in all ihren unterschiedlichen Facetten gedächtnis- und erinnerungspolitische Aspekte implizieren. (shrink)

Das Archiv steht hoch im Kurs. Sowohl als Schauplatz theoretischer Auseinandersetzungen als auch als Gegenstand archivwissenschaftlicher Reflexionen und Neubewertungen bietet es unterschiedliche philosophische, kultur- und archivwissenschaftliche Zugänge, die miteinander korrespondieren oder sich in expliziten Widerspruch zueinander stellen. Was die philosophisch-kulturwissenschaftlichen und die archivwissenschaftlichen Zugänge jedoch verbindet, sind die Fragen nach den Gesetzmäßigkeiten, nach den Zuordnungen und den Vergegenwärtigungen, die im Archiv stattfinden und im Archiv ihren Ort haben. Der Parcours durch die unterschiedlichen Archiv-Konzeptionen, der in diesem Aufsatz unternommen wird, fokussiert (...) auf eben diese Fragestellungen, die in all ihren unterschiedlichen Facetten gedächtnis- und erinnerungspolitische Aspekte implizieren. (shrink)

Technologien haben schon lange Eingang in unseren Alltag gefunden und transformieren zahlreiche Lebensbereiche wie Politik, Wirtschaft, Bildung, Gesundheit und Pflege. Mittels Social Media pflegen wir zwischenmenschliche Beziehungen und kommunizieren miteinander, wir haben Apps zum Schlafen oder für die Ernährung und in der Medizin werden Technologien in den Körper implantiert oder zur Untersuchung des Körpers verwendet. Wearables, wie z. B. die Smart Watch, werden direkt am Körper getragen und müssen kaum noch abgenommen werden. Smart Watches messen den Puls und Herzschlag, zählen (...) unsere Schritte, melden sich, wenn man wieder aufstehen sollte und erfassen den Schlafrhythmus. Wir schlagen Wissen bei Wikipedia nach und lernen interaktiv über Smart Boards in der Schule. Über digitale Tools lässt sich das orts- und zeitunabhängige Zusammenarbeiten organisieren. Wie verändert sich das Menschsein in einer solchen technisierten Welt? Wie verändern sich die menschliche Lebenswelt, Handeln, Verantwortungsstrukturen und Identitätskonzepte? Puzio, Anna/Rutzmoser, Carolin/Endres, Eva-Maria: Menschsein in einer technisierten Welt – Einleitende Bemerkungen zu einer interdisziplinären Auseinandersetzung mit der digitalen Transformation. In: Endres, Eva-Maria/Puzio, Anna/Rutzmoser, Carolin (Hg.): Menschsein in einer technisierten Welt. Interdisziplinäre Perspektiven auf den Menschen im Zeichen der digitalen Transformation. Wiesbaden 2022. (shrink)

This study examines the effect of integrating sustainability into corporate strategy on various aspects of shareholder value creation and financial performance in the British capital market. The employed method is based on the content analysis of corporate disclosures and a new technique for assessing the adoption of the corporate sustainability concept. Using extensive data of FTSE 350 firms covering the years 2006–2012, 65 companies were selected as meeting corporate sustainability criteria. For the above period, we find that these firms were (...) characterized by higher financial risk exposure, lower asset growth rates, lower BV/MV ratios, lower EVA ratios, and higher MVA ratios. Such relations were generally present among different size and industry groupings. The results support the thesis that firms that incorporate sustainability issues into their business operations are better able to leverage their resources toward stronger financial performance and shareholder value creation than other companies. The paper contributes to the literature by offering a more holistic approach to corporate sustainable performance measurement and shedding additional light on its relation to financial performance in the context of the recent global financial crisis and its direct aftermath. (shrink)

Whether firms can be said to be moral agents and to have the capacity for moral responsibility has significant practical consequences. In most legal systems in the world, business firms are recognized as persons with the ability to own property, to maintain and defend lawsuits, and to self-organize governance structures. To recognize that these business persons can also act morally or immorally as organizations, however, would justify the imposition of other legal constraints and normative expectations on organizations. In the criminal (...) law, for example, the idea that an organized firm may itself have criminal culpability is accepted in many countries (such as the United States) but rejected in others (such as Germany). This book collects new contributions by leading business scholars in business ethics, philosophy, and related disciplines to extend our understanding of the moral responsibility of firms. (shrink)

Eva Picardi has been one of the most influential Italian analytic philosophers of her generation. She taught for forty years at the University of Bologna, raising three generations of students. This collection of selected writings honors her work, confirming Picardi's status as one of the most important Frege scholars of her generation and a leading authority on the philosophy of Donald Davidson. Bringing together Picardi's contributions to the history of analytic philosophy, it includes her papers on major 20th-century figures such (...) as Wittgenstein, Quine, Davidson, Rorty, and Brandom. She examines their work in comparison with the philosopher Michael Dummett's, illuminating contrasts between American Neo-pragmatism and Continental philosophy. By considering key contributions made by Gadamer and Adorno and contrasting them with Davidson and Rorty's proposals, Picardi is able to bridge the Analytic and Continental divide. Featuring an introduction by Annalisa Coliva and new translations of previously unpublished papers, this collection emphasizes the significance of Picardi's work for a new generation of readers. (shrink)

With regard to current debates on the ethical implementation of AI, especially two demands are linked: the call for explainability and for ultimate human responsibility. In the medical field, both are condensed into the role of one person: It is the physician to whom AI output should be explainable and who should thus bear ultimate responsibility for diagnostic or treatment decisions that are based on such AI output. In this article, we argue that a black box AI indeed creates a (...) rationally irresolvable epistemic situation for the physician involved. Specifically, strange errors that are occasionally made by AI sometimes detach its output from human reasoning. Within this article it is further argued that such an epistemic situation is problematic in the context of ultimate human responsibility. Since said strange errors limit the promises of explainability and the concept of explainability frequently appears irrelevant or insignificant when applied to a diverse set of medical applications, we deem it worthwhile to reconsider the call for ultimate human responsibility. (shrink)

SECCIÓN PRIMERAMétodo, Historia, FundamentosCAPÍTULO I. Un ejemplo literario de Derecho penal del enemigoI. El capítulo cervantino de los galeotes como fundamento epistemológicodel Derecho penal del enemigoII. Las enseñanzas penales del pasaje cervantino.

Цель данного издания - познакомить широкий круг читателей с основными вехами жизни ученого, организатора, ее научными трудами, литературой о ней.

A beautifully clear and accessible explanation of how to live a Taoist life--by reknowned Taoist master Eva Wong. Being Taoist is one of the most readable books on Taoist philosophy available. It shines a light on exactly what it takes to live a Taoist life. Taoist living rests on four pillars--the public, the domestic, the private, and the spirit lives. Not only do Taoists strive to live these four aspects fully and in a balanced way, they also believe there is (...) an outlook and an art to each of them. Eva Wong uses the teachings of Taoist masters (one for each pillar) to explain the essential concepts. She then gives voice to these texts--simplifying them, removing barriers to understanding, and making them completely accessible and relevant to the modern reader. Wong is a clear and enthusiastic guide to this intriguing spiritual Way, and she challenges us to stop, reflect, and ask ourselves: Do we balance the public, domestic, private, and spirit aspects in our lives? Do we emphasize some at the expense of the others? Do we ever think about unifying worldly and spiritual wisdom in our lives? (shrink)

In der Öffentlichkeit häufig als Auswanderungsland wahrgenommen, unternahm China in den letzten Jahren verstärkt Bemühungen, qualifizierte Fachkräfte aus dem Ausland für den chinesischen Arbeitsmarkt zu gewinnen. Die Einführung eines Fachkräfteeinwanderungssystem mit abgestuften Rechten für Arbeitsmigrant:innen sollte diese Entwicklung fördern. Die vorliegende Analyse zeigt, dass diese Reform des Einwanderungssystems die Gerichtspraxis nicht verändert hat. Abseits der politischen Diskurse um die Anwerbung von internationalen Talenten und der Propagierung Chinas als Wissenssupermacht, bleibt China aufgrund der existierenden Probleme im bestehenden Rechtssystems für Arbeitsmigrant:innen unattraktiv.

Georg Wilhelm Friedrich Hegel und die Weiter- und Höherenentwicklung seiner Ideen, von A. Abusch.-G.W.F. Hegel und seine Zeit (1770-1831). Eine Chronik.-G.W.F. Hegels Werke in Erstausgaben.-Aus Werken Hegels.-Marx, Engels, Lenin über Hegel.-Hegel Literatur in der DDR 1949-1969.-Hegel Literatur zum Hegel Jahr 1970.-Veranstaltungen aus Anlass des 200. Geburtstages von G.W.F. Hegel am 27. August 1970.

В сборнике представлены работы, посвященные опыту истории государственно-конфессиональных отношений в России, а также проблемам свободомыслия в истории религиозной и общественно-политической жизни, теории и практике марксистско-ленинского атеизма.

Eva Picardi was one of the most influential Italian analytic philosophers of her generation. She taught for forty years at the University of Bologna, raising three generations of students. This volume presents a selection of Picardi's essays on Frege's philosophy of logic, language, and psychology. Together, these papers provide a close look at the milieu within which Frege operated, and serve to highlight the relevance of his work for contemporary debates, particularly in the philosophy of language. One strand in Picardi's (...) work on Frege concerns understanding and contextualizing Frege's anti-psychologism. Picardi contends that Frege was motivated by semantic considerations, much more so than by adherence to Kantian transcendentalism. Furthermore, Picardi draws on her deep knowledge of German, and the fact that she was a native speaker of Italian, to reconstruct the intricacies of Frege's relationship with other logicians of his time-both in Germany, like Kerry and Sigwart, and in Italy, like Peano and his school. Picardi's work shows how the historical and the theoretical, complement and enrich one another. (shrink)

Ideas about heredity and evolution are undergoing a revolutionary change. New findings in molecular biology challenge the gene-centered version of Darwinian theory according to which adaptation occurs only through natural selection of chance DNA variations. In Evolution in Four Dimensions, Eva Jablonka and Marion Lamb argue that there is more to heredity than genes. They trace four "dimensions" in evolution -- four inheritance systems that play a role in evolution: genetic, epigenetic, behavioral, and symbolic. These systems, they argue, can all (...) provide variations on which natural selection can act. Evolution in Four Dimensions offers a richer, more complex view of evolution than the gene-based, one-dimensional view held by many today. The new synthesis advanced by Jablonka and Lamb makes clear that induced and acquired changes also play a role in evolution.After discussing each of the four inheritance systems in detail, Jablonka and Lamb "put Humpty Dumpty together again" by showing how all of these systems interact. They consider how each may have originated and guided evolutionary history and they discuss the social and philosophical implications of the four-dimensional view of evolution. Each chapter ends with a dialogue in which the authors engage the contrarieties of the fictional "I.M.," or Ifcha Mistabra -- Aramaic for "the opposite conjecture" -- refining their arguments against I.M.'s vigorous counterarguments. The lucid and accessible text is accompanied by artist-physician Anna Zeligowski's lively drawings, which humorously and effectively illustrate the authors' points. (shrink)

The attitude of believing or "holding true" fulfils a twofold role in Davidson's theory of meaning: it provides the basic evidence for a theory of radical interpretation and it also constitutes the key notion in terms of which the linguistic act of assertion is to be characterized. It is however doubtful whether the notion of "holding true" can fulfil either of these two roles without presupposing an implicit grasp of the public significance of the practice of making assertions. The lack (...) of specific conventions governing assertoric force and linking assertion to what is believed true is no ground for supposing that a theory of meaning can dispense with an account of the act of assertion: on the contrary, such an account is indispensable if we are to understand the bearing of the notion of truth on that of linguisticmeaning. (shrink)

BackgroundThis article aims to contribute to a better conceptualization of pain and suffering by providing non-essential and non-naturalistic definitions of both phenomena. Contributions of classical evidence-based medicine, the humanistic turn in medicine, as well as the phenomenology and narrative theories of suffering and pain, together with certain conceptions of the person beyond them are critically discussed with such purpose.MethodsA philosophical methodology is used, based on the review of existent literature on the topic and the argumentation in favor of what are (...) found as better definitions of suffering and pain.ResultsPain can be described in neurological terms but cognitive awareness, interpretation, behavioral dispositions, as well as cultural and educational factors have a decisive influence on pain perception. Suffering is proposed to be defined as an unpleasant or even anguishing experience, severely affecting a person at a psychophysical and existential level. Pain and suffering are considered unpleasant. However, the provided definitions neither include the idea that pain and suffering can attack and even destroy the self nor the idea that they can constructively expand the self; both perspectives can b e equally useful for managing pain and suffering, but they are not defining features of the same. Including the existential dimension in the definition of suffering highlights the relevance of suffering in life and its effect on one’s own attachment to the world. An understanding of pain and suffering life experiences is proposed, meaning that they are considered aspects of a person’s life, and the self is the ever-changing sum of these experiences.ConclusionsThe provided definitions will be useful to the identification of pain and suffering, to the discussion of how to relieve them, and to a better understanding of how they are expressed and experienced. They lay the groundwork for further research in all these areas, with the twofold aim of a) avoiding epistemological mistakes and moral injustices, and b) highlighting the limitations of medicine in the treatment of suffering and pain. (shrink)

Johann Gottfried Herder initiated the modern disciplines of philosophical anthropology and cultural history, including the study of popular culture. He is also remembered as a sharp critic of colonialism and imperialism. But what types of social, economic and political arrangements did Herder envision for modern European societies? Herder and Enlightenment Politics provides a radically new interpretation of Herder's political thought, situating his ideas in Enlightenment debates on modern patriotism, commerce and peace. By reconstructing Herder's engagement with Rousseau, Montesquieu, Abbt, Ferguson, (...) Möser, Kant and many other contemporary authors, Eva Piirimäe shows that Herder was deeply interested in the potential for cultural, moral and political reform in Russia, Germany and Europe. Herder probed the foundations of modern liberty, community and peace, developing a distinctive understanding of human self-determination, natural sociability and modern patriotism as well as advocating a vision of Europe as a commercially and culturally interconnected community of peoples. (shrink)