We design an agent based Monte Carlo model of antibiotics research and development to explore the effects of the policy intervention known as Market Entry Reward on the likelihood that an antibiotic entering pre-clinical development reaches the market. By means of sensitivity analysis we explore the interaction between the MER and four key parameters: projected net revenues, R&D costs, venture capitalists discount rates, and large pharmaceutical organizations' financial thresholds. We show that improving revenues may be more efficient than reducing costs, (...) and thus confirm that this pull-based policy intervention effectively stimulates antibiotics R&D. (shrink)

In Minimal Rationality, Christopher Cherniak boldly challenges the myth of Man the the Rational Animal and the central role that the "perfectly rational...

Moral judgments attempt to describe a reality that does not exist, so they are all false. This troubling view is known as the moral error theory. Christopher Cowie defends it against the most compelling counter-argument, the argument from analogy: Cowie shows that moral error theory does not compromise the practice of making epistemic judgments.

Recent work in argumentation theory has emphasized the nature of arguers and arguments along with various theoretical perspectives. Less attention has been given to the third feature of any argumentative situation - the audience. This book fills that gap by studying audience reception to argumentation and the problems that come to light as a result of this shift in focus. Christopher W. Tindale advances the tacit theories of several earlier thinkers by addressing the central problems connected with audience considerations (...) in argumentation, problems that earlier philosophical theories overlook or inadequately accommodate. The main tools employed in exploring the central issues are drawn from contemporary philosophical research on meaning, testimony, emotion and agency. These are then combined with some of the major insights of recent rhetorical work in argumentation to advance our understanding of audiences and suggest avenues for further research. (shrink)

What is the relation between the nature of the things you think about, and the ways you think about them? Christopher Peacocke argues that meaning is never prior to metaphysics - to the nature of the world. He shows that this view holds for a wide range of topics, including magnitudes, time, the self, and abstract objects such as numbers.

ABSTRACT It has been frequently observed in the literature that assertions of plain sentences containing predicates like fun and frightening give rise to an acquaintance inference: they imply that the speaker has first-hand knowledge of the item under consideration. The goal of this paper is to develop and defend a broadly expressivist explanation of this phenomenon: acquaintance inferences arise because plain sentences containing subjective predicates are designed to express distinguished kinds of attitudes that differ from beliefs in that they can (...) only be acquired by undergoing certain experiences. Its guiding hypothesis is that natural language predicate expressions lexically specify what it takes for their use to be properly ‘grounded’ in a speaker's state of mind: what state of mind a speaker must be in for a predication to be in accordance with the norms governing assertion. The resulting framework accounts for a range of data surrounding the acquaintance inference as well as for striking parallels between the evidential requirements on subjective predicate uses and the kind of considerations that fuel motivational internalism about the language of morals. A discussion of how the story can be implemented compositionally and of how it compares with other proposals currently on the market is provided. (shrink)

This Open Access book combines philosophical and historical analysis of various forms of alternatives to mechanism and mechanistic explanation, focusing on the 19th century to the present. It addresses vitalism, organicism and responses to materialism and its relevance to current biological science. In doing so, it promotes dialogue and discussion about the historical and philosophical importance of vitalism and other non-mechanistic conceptions of life. It points towards the integration of genomic science into the broader history of biology. It details a (...) broad engagement with a variety of nineteenth, twentieth and twenty-first century vitalisms and conceptions of life. In addition, it discusses important threads in the history of concepts in the United States and Europe, including charting new reception histories in eastern and south-eastern Europe. While vitalism, organicism and similar epistemologies are often the concern of specialists in the history and philosophy of biology and of historians of ideas, the range of the contributions as well as the geographical and temporal scope of the volume allows for it to appeal to the historian of science and the historian of biology generally. (shrink)

Subjective predicates have two interpretive and distributional characteristics that have resisted a comprehensive analysis. First, the use of a subjective predicate to describe an object is in general felicitous only when the speaker has a particular kind of familiarity with relevant features of the object; characterizing an object as _tasty,_ for example, implies that the speaker has experience of its taste. Second, subjective predicates differ from objective predicates in their distribution under certain types of propositional attitude verbs. The goal of (...) this paper is to argue that these features can be explained in a uniform way and within a broadly truth-conditional approach to semantic content, given a view of subjective language as an essentially pragmatic, context-sensitive phenomenon. Specifically, we propose that what renders an issue subjective in discourse is speakers’ awareness of _counterstance contingency_: contingency relative to information states that represent alternative pragmatic stances. (shrink)

_Unequivocal Justice_ challenges the prevailing view within political philosophy that broadly free market regimes are inconsistent with the basic principles of liberal egalitarian justice. Freiman argues that the liberal egalitarian rejection of free market regimes rests on a crucial methodological mistake. Liberal egalitarians regularly assume an ideal "public interest" model of political behavior and a nonideal "private interest" model of behavior in the market and civil society. Freiman argues that this asymmetrical application of behavioral assumptions biases the analysis and undercuts (...) ideal theoretical treatments of every major liberal egalitarian principle, including political liberty, economic sufficiency, fair opportunity, and social equality. This book reexamines the institutional implications of each of these principles in nonideal conditions, making novel philosophical use of political psychology and public choice economics along the way. (shrink)

In The Struggle for Democracy, Christopher Meckstroth looks at history and context in the development of democratic theory to provide a principled way of sorting out deep conflicts over who has the right to speak for the democratic people. He tests this theory by applying it to contemporary debates over same-sex marriage, military intervention, and gun control.

BackgroundTo help inform the development of more accessible, acceptable, and effective ethics consultation (EC) training programs, we conducted an EC training needs assessment, exploring ethics practitioners’ opinions on: the relative importance of various EC practitioner competencies; the potential market for EC training (that is, how many individuals would benefit and how much individuals and hospitals would be willing to pay); and the preferred content, format, and characteristics of EC training.MethodsAs part of a multipart study, we surveyed “best informants” who self-identified (...) as the person most actively involved in EC or healthcare ethics in a random sample of 600 U.S. general hospitals, stratified for bed size.ResultsThe competency that was ranked most important for a lead or solo ethics consultant was knowledge of ethics, while common sense was ranked least important. The median estimated number of individuals at each hospital who would benefit from EC training was six at the basic level, three at the advanced level, and two for EC management training. In 19.1 percent of hospitals, respondents thought their hospital would not be willing to pay anything for EC training within the next two years. Respondents thought potential trainees would be likely to participate in EC training on multiple different topics. Opinions varied widely on preferred formats. Most respondents thought it very important to be able to interact with instructors and with other trainees, practice EC skills, receive a certificate for completing EC training, and complete EC training during work hours.ConclusionsThese findings provide U.S. population data that may be useful to healthcare educators and bioethics leaders in their efforts to develop EC training programs and products that match trainees’ preferences and needs. (shrink)

Ever since Parmenides, one of philosophy's riddles has been how we are able to direct our thoughts to non-being. Erhard uses the problem of non-existence as the starting point for an analysis of Husserl's phenomenology. He examines Husserl's interpretation of judgments about non-being as judgments made "under assumption" and his analysis of "free fantasy." Erhard thus demonstrates that Husserl is compatible with today's non-relational theories.

Basing his view on the object relations theories of the "British School" of psychoanalysis, Christopher Bollas examines the human subject's memories of its earliest experiences (during infancy and childhood) of the object, whether it be mother, father, or self. He explains in well-written and non-technical language how the object can affect the child, or "cast in shadow," without the child being able to process this relation through mental representations of language.

This is a reply to “What Makes a Home” by Kimberley Brownlee and David Jenkins. In it, I defend my own account of homelessness, which I call the ‘legal conception’ against their criticism and try to illustrate the differences between my view and theirs, which I call the ‘social conception.’.

An Essay on the Relation Between Thought and Language Christopher Gauker. things possible? How, having once perceived the herds by the lake, does the agent remember this for later use? My answer is that one way he may do it is ...

This book is a critical introduction to the long-standing debate concerning the conceptual foundations of quantum mechanics and the problems it has posed for physicists and philosophers from Einstein to the present. Quantum theory has been a major infulence on postmodernism, and presents significant problems for realists. Keeping his own realist position in check, Christopher Norris subjects a wide range of key opponents and supporters of realism to a high and equal level of scrutiny. With a characteristic combination of (...) rigour and intellectual generosity, he draws out the merits and weaknesses from opposing arguments. In a sequence of closely argued chapters, Norris examines the premises of orthodox quantum theory, as developed most influentially by Bohr and Heisenberg, and its impact on varous philosophical developments. These include the ideas developed by W.V Quine, Thomas Kuhn, Michael Dummett, Bas van Fraassen, and Hilary Puttnam. In each case, Norris argues, these thinkers have been influenced by the orthodox construal of quantum mechanics as requiring drastic revision of principles which had hitherto defined the very nature of scientific method, causal explanati and rational enquiry. Putting the case for a realist approach which adheres to well-tried scientific principles of causal reasoning and inference to the best explanation, Christopher Norris clarifies these debates to a non-specialist readership and scholars of philosophy, science studies and the philosophy of science alike. Quantum Theory and the Flight From Realism suggests that philosophical reflection can contribute to a better understanding of these crucial, current issues. (shrink)

Aristotle outlines two methods in De Anima that one can employ when one investigates the soul. The first focuses on the exercises of a living organism’s vital capacities and the proper objects upon which these activities are directed. The second focuses on a living organism’s nature, its internal principle of movement and rest, and the single end for the sake of which this principle is exercised. I argue that these two methods yield importantly different, and prima facie incompatible, views about (...) what souls are. According to the first, the soul is a set of independently specifiable capacities that are related to one another in a manner that effects a unity of soul over and above the multiplicity. According to the second, the soul is a single, unitary nature that has a living organism’s form as its end. I bring the differences between these two conceptions of soul into relief and then attempt to reconcile the opposing views in a way privileges the conception according to which the soul is a unitary nature. In doing so, I discuss the following interrelated topics: (a) what makes a capacity a part of soul, (b) the relationship between the parts of soul within a given organism, (c) how a soul can be a unity while comprising various parts, (d) whether it is possible to give an adequate definition of life or soul, (e) what unity obtains among the various ways life is said that would allow for a proper, scientific investigation of life, and (f) the principle that grounds the hierarchy of souls—the nutritive, the perceptual, and the rational. (shrink)

The words 'rebellion' and 'revolution' have gained renewed prominence in the vocabulary of world politics and so has the question of justifiable armed 'resistance'. In this book Christopher J. Finlay extends just war theory to provide a rigorous and systematic account of the right to resist oppression and of the forms of armed force it can justify. He specifies the circumstances in which rebels have the right to claim recognition as legitimate actors in revolutionary wars against domestic tyranny and (...) injustice, and wars of liberation against wrongful foreign occupation and colonialism. Arguing that violence is permissible only in a narrow range of cases, Finlay shows that the rules of engagement vary during and between different conflicts and explores the potential for irregular tactics to become justifiable, such as non-uniformed guerrillas and civilian disguise, the assassination of political leaders and regime officials, and the waging of terrorist war against civilian targets. (shrink)

Seth Shabo has presented a new argument that attempts to codify familiar worries about indeterminism, luck, and control. His ‘Assimilation Argument’ contends that libertarians cannot distinguish overtly randomized outcomes from exercises of free will. Shabo claims that the argument possesses advantages over the Mind Argument and Rollback Argument, which also purport to establish that indeterminism is incompatible with free will. I argue first that the Assimilation Argument presents no new challenges over and above those presented by the Rollback Argument, and (...) second that the Rollback Argument itself neither presents a deep challenge to, nor raises the cost of, accepting libertarianism. (shrink)

Eric Katz in Zombie Arguments defends the thesis authenticity is indispensable to conservation. I agree. However, I argue authenticity appears in degrees and can be reclaimed by populations through their continuing evolutionary responses to the world. This means that interventions that diminish the value of a population through reducing their authenticity can be permitted in limited cases. When our actions retain the remaining authentic features in a threatened population we should allow such a diminishment as authenticity can be reclaimed in (...) time. (shrink)

"If you turn left at the next corner, you will see a blue house at the end of the street." That sentence -- a conditional -- might be true even though it is possible that you will not see a blue house at the end of the street when you turn left at the next corner. A moving van may block your view; the house may have been painted pink; a crow might swoop down and peck out your eyes. Still, (...) in some contexts, we might ignore these possibilities and correctly assert the conditional. In this book, Christopher Gauker argues that such context-relativity is the key to understanding the semantics of conditionals. Contexts are defined as objective features of the situation in which a conversation takes place, and the semantic properties of sentences -- conditionals included -- are defined in terms of assertibility in a context. One of the primary goals of a theory of conditionals has to be to distinguish correctly between valid and invalid arguments containing conditionals. According to Gauker, an argument is valid if the conclusion is assertible in every context in which the premises are assertible. This runs counter to what Gauker sees as a systematic misreading of the data by other authors, who judge arguments to be invalid if they can think of a context in which the premises are judged true and some other context in which the conclusion is judged false. Different schools of thought on conditionals reflect fundamentally different approaches to semantics. Gauker offers his theory as a motive and test case for a distinctive kind of semantics that dispenses with reference relations and possible worlds. (shrink)

Journal of Philosophy of Education, EarlyView.

The partial structures program of da Costa, French and others offers a unified framework within which to handle a wide range of issues central to contemporary philosophy of science. I argue that the program is inadequately equipped to account for simple cases where idealizations are used to construct abstract, mathematical models of physical systems. These problems show that da Costa and French have not overcome the objections raised by Cartwright and Suárez to using model‐theoretic techniques in the philosophy of science. (...) However, my concerns arise independently of the more controversial assumptions that Cartwright and Suárez have employed. (shrink)

Human neural and behavioral activities have been reported to exhibit fractal dynamics known as 1/f noise, which is more aptly named 1/f scaling. Some argue that 1/f scaling is a general and pervasive property of the dynamical substrate from which cognitive functions are formed. Others argue that it is an idiosyncratic property of domain‐specific processes. An experiment was conducted to investigate whether 1/f scaling pervades the intrinsic fluctuations of a spoken word. Ten participants each repeated the word bucket over 1,000 (...) times, and fluctuations in acoustic measurements across repetitions generally followed the 1/f scaling relation, including numerous parallel yet distinct series of 1/f fluctuations. On the basis of work showing that 1/f scaling is a universal earmark of metastability, it is proposed that the observed pervasiveness of 1/f fluctuations in speech reflects the fact that cognitive functions are formed as metastable patterns of activity in brain, body, and environment. (shrink)

What is subsistence and does it constitute an individual substance which is distinct from its individual nature? Relying upon Thomas, and to a lesser extent, his successors, this dissertation presents a probable solution. This is a thematically organized study, with much textual analysis and a strong attendant interest in the problems of explicating authentically the meaning and systematic coherence of Thomas's doctrine of subsistence. Arguing from authority and reason, this dissertation tries to present the reality and ratio of the supposit (...) and subsistence in three contexts. ;Chapter One examines Thomas's metaphysics of being and how the supposit relates to a being's reality, principles, and modes. The notions of a being , its transcendentals, existence , nature, and substance are examined, and then the supposit and its proper determinations are situated within the context of these constitutive factors and aspects. ;Chapter Two shows how some of these principles are manifested in Thomas's account of the hierarchy of subsistents. Are nature and supposit distinct in certain substances? If distinct, what principles bring about such a distinction? Is esse an act in regard to a supposit or to a nature? What is the act of existence and must it be distinguished from other existential realities? Is a supposit composed of a substantial thing and esse? Or does it compose with esse? ;Chapter Three examines the doctrine of subsistence which arises from Thomas's studies of the Trinity and the Incarnation. In these contexts, the supposit as a subsistent distinct from its individual nature is explicitly presented. By the end of this chapter, the exposition of subsistence according to the mind of Thomas should be more manifest. ;The conclusion presents a summary, recalling the major evidences for the most reasonable and authentically Thomist notion of subsistence: a substantial term. (shrink)

The architectural photographer Julius Shulman (1910-2009) is one of the few image makers to have documented, as well as witnessed, nearly an entire century of Los Angeles history.

The arrival of Covid-19 in 2020 brought severe disruption to our public and our private lives, and also to ordinary normative boundaries we maintain between the two which we had previously taken fo...

Whether or not youth work should professionalise and to what degree governments should regulate youth work services have been a widely debated topic within the Australian youth sector in recent tim...

The use of focus groups is a well‐established qualitative research method in the social sciences that would seem to offer scope for a significant contribution to the advancement of knowledge and understanding in the field of business ethics. This paper explores the potential contribution of focus groups, reviews their contribution to date and makes some recommendations regarding their future use. We find that, while the use of focus groups is not extensive, they have been utilised in a non‐negligible number of (...) studies. Focus groups are usually used as a supplementary method, often as part of the development of a research instrument. Whether used on their own or in conjunction with other methods, we find that in the majority of cases there is insufficient information for a reader to judge that the method has been carried out well and hence that the ‘findings’ may be trusted. Nor is it easy for future researchers to learn about the practical application of the method in business ethics contexts. We therefore recommend improved reporting in future published studies. Based on an analysis of a subsample of papers that provided a reasonable level of methodological detail, we provide further insights into, and recommendations for, the use of focus groups in business ethics research. (shrink)

Christopher Hookway; I *—The Presidential Address: Questions of Context, Proceedings of the Aristotelian Society, Volume 96, Issue 1, 1 June 1996, Pages 1–16, h.

Mathematical models of biological patterns are central to contemporary biology. This paper aims to consider what these models contribute to biology through the detailed consideration of an important case: Hamilton’s selfish herd. While highly abstract and idealized, Hamilton’s models have generated an extensive amount of research and have arguably led to an accurate understanding of an important factor in the evolution of gregarious behaviors like herding and flocking. I propose an account of what these models are able to achieve and (...) how they can support a successful scientific research program. I argue that the way these models are interpreted is central to the success of such programs. (shrink)

Dr Lloyd writes for those who want to discover and explore Aristotle's work for themselves. He acts as mediator between Aristotle and the modern reader. The book is divided into two parts. The first tells the story of Aristotle's intellectual development as far as it can be reconstructed; the second presents the fundamentals of his thought in the main fields of inquiry which interested him: logic and metaphysics, physics, psychology, ethics, politics, and literary criticism. The final chapter considers the unity (...) and coherence of Aristotle's philosophy, and records briefly his later influence on European thought. This is a concise and lucid account of the work of a difficult and profound thinker. Dr Lloyd's business is only with the essentials; but he does not shirk the difficulties which arise in their interpretation, nor does he invest Aristotle with a spurious modernity. (shrink)

The prelims comprise: Justificatory Liberalism Justificatory vs. Mere Liberalism Why Public Justification? The Argument from Respect Evaluation of Larmore's Argument from Respect A General Problem for the Argument from Respect The Argument from Religious Warfare The Argument from Divisiveness What Is Public Justification? Conclusion Notes Bibliography.

The Quaestiones super Physica Aristotelis traditionally attributed to Iohannes Canonicus survive in over 35 manuscripts and at least 8 printings from 1475 to 1520. Yet historians have disagreed about the century, the place of origin, the name and the institutional position of the author. This brief paper combines old and new evidence proving that the text was authored by an Augustinian Canon Regular of the Cathedral of Tortosa named Francesc Marbres, a Catalan from Barcelona, while he was Master of Arts (...) at the University of Toulouse around 1330. (shrink)

Drawing on a wide range of films from around the world, and the ideas of a diverse selection of thinkers from Plato and Descartes to Marcuse and Foucault, _Philosophy Goes to the Movies_ introduces and discusses central areas of philosophical concern, including: *the theory of knowledge *the self and personal identity *ethics *social and political philosophy *critical thinking Ideal for beginners, this book guides the reader through philosophy using lively and illuminating cinematic examples including _A Clockwork Orange_, _Mulholland Drive_, _Blade (...) Runner_, _Modern Times_, _Wings of Desire_ and _The Lord of the Rings_. This fully revised and updated second edition features an expanded introduction providing guidance on teaching and discussing philosophy through film, as well as new material on notable philosophers such as Rousseau, Aquinas and Nietzche, and discussion of a wide range of recent films. (shrink)

If ecological systems are functionally organised, they can possess functions or malfunctions. Natural function would provide justification for conservationists to act for the protection of current ecological arrangements and control the presence of populations that create ecosystem malfunctions. Invasive species are often thought to be malfunctional for ecosystems, so functional arrangement would provide an objective reason for their control. Unfortunately for this prospect, I argue no theory of function, which can support such normative conclusions, can be applied to large scale (...) ecosystems. Instead ecological systems have causal structure, with small clusters of populations achieving functional arrangement. This, however, does not leave us without reason to control invasive species. We can look at the causal arrangement of ecological systems for populations that support ecological features that we should preserve. Populations that play a causal role in reducing biodiversity should be controlled, because biodiversity is a good all prudent agents should want to preserve. (shrink)

First Published in 2002. Routledge is an imprint of Taylor & Francis, an informa company.