Estudio bibliográfico de: / A Bibliographical Study of: G. Patella, Senso, corpo, poesia. Giambattista Vico e l¿origine dell¿estetica moderna (Milán, 1995); y de S. Velotti, Sapienti e bestioni. Saggio sull¿ignoranza, il sapere e la poesia in Giambattista Vico (Parma, 1995).

Lichtung -- La questione del domandare -- L'altro inizio -- Incontro a Hölderlin -- Essere e linguaggio -- Congedo dall'essere -- Il colloquio dei mortali.

La concepción del amor como movimiento hacia valores superiores se inspira en la descripción del fenómeno amoroso por antonomasia: el amor a seres personales. Pese a sus indudables méritos, el tratamiento de esta forma de amor ofrecido por Scheler adolece del defecto de no aclarar suficientemente cómo está dada en el amor la individualidad del amado. También es objetable que, al distinguir las formas principales del amor, Scheler interprete el amor espiritual como amor a los valores de lo santo; (...) y más aún que termine considerando el amor amicitiae como un caso de amor anímico. (shrink)

La concepción del amor como movimiento hacia valores superiores se inspira en la descripción del fenómeno amoroso por antonomasia: el amor a seres personales. Pese a sus indudables méritos, el tratamiento de esta forma de amor ofrecido por Scheler adolece del defecto de no aclarar suficientemente cómo está dada en el amor la individualidad del amado. También es objetable que, al distinguir las formas principales del amor, Scheler interprete el amor espiritual como amor a los valores de lo santo; (...) y más aún que termine considerando el amor amicitiae como un caso de amor anímico. (shrink)

Gianluca De Fazio’s book Avversità e margini di gioco. Studio sulla soggettività in Merleau-Ponty presents precise and original research along several nodes of great importance in Merleau-Ponty’s philosophical production, such as subjectivity, expression, passivity, nature, history. By focusing on, without limiting himself to, the 1950’s period, the author declares that he aims at a denaturalization of nature and a dehistoricization of history: an overcoming of dichotomies which, though faithfully following the Merleau-Pontian path, does not fail to have a Deleuzian overtones. (...) The issues of the book are also, and above all, political, shown in the considerations of the task of philosophy. (shrink)

While Conviction Narrative Theory correctly criticizes utility-based accounts of decision-making, it unfairly reduces probabilistic models to point estimates and treats affect and narrative as mechanistically opaque yet explanatorily sufficient modules. Hierarchically nested Bayesian accounts offer a mechanistically explicit and parsimonious alternative incorporating affect into a single biologically plausible precision-weighted mechanism that tunes decision-making toward narrative versus sensory dependence under varying uncertainty levels.

A fibromialgia é uma síndrome crônica, não inflamatória caracterizada por dores musculoesqueléticas difusas e pela presença de pontos dolorosos em determinadas regiões do corpo "Tender Points". Seu diagnóstico é clínico, não havendo alterações laboratoriais específicas. O enfoque deste trabalho é co..

Palabras de agradecimiento al promotor del Congreso Internacional y a los participantes en él. Asimismo, a la persona que ha trabajado en la labor de transcripción de mis escritos y a otros colaboradores míos. También a quienes han tomado en cuenta mis ideas para elaborar sus tesis doctorales, y a otros colegas cuyos planteamientos filosóficos distan de los míos. Como la filosofía es una actividad interminable, queda abierta la sucesiva investigación en mis propuestas.

The interest in what can be considered 'posthumanism' has surged over the past few years. There is no surprise as to why, given the urgency and immanence of a likely sixth mass extinction event, and the catastrophic consequences of global warming. These processes, all of which fundamentally rest on the foundations of human practices and abuses, are forcing us to rethink our place in existence. The foundations of this position have a history firmly rooted in the daily practices and beliefs (...) of Western cultures. The Contemporary Posthuman confronts these assumptions of truth, head-on. The author follows his conceptual journey with practical steps for putting his philosophy into practice, by drawing on philosophy, design, art, and architecture. (shrink)

Este artigo visa apresentar uma taxonomia original dos argumentos mais difundidos contra o Princípio de Identidade dos Indiscerníveis ao longo da história da Filosofia, mas focando em versões defendidas no século XX e XXI; bem como uma taxonomia das respostas mais efetivas para esses argumentos usados no início do século XXI com uma breve avaliação sobre quais são as mais efetivas para cada argumento de ataque. O leitor também encontrará uma bibliografia atualizada sobre os debates envolvendo esses argumentos e contra-argumentos (...) nas seções correspondentes. Palavras-chave: identidade; indiscernibilidade; Princípio de Identidade dos Indiscerníveis; concebilidade. (shrink)

Organization figures centrally in the understanding of biological systems advanced by both new mechanists and proponents of the autonomy framework. The new mechanists focus on how components of mechanisms are organized to produce a phenomenon and emphasize productive continuity between these components. The autonomy framework focuses on how the components of a biological system are organized in such a way that they contribute to the maintenance of the organisms that produce them. In this paper we analyze and compare these two (...) accounts of organization and argue that understanding biological organisms as cohesively integrated systems benefits from insights from both. To bring together the two accounts, we focus on the notions of control and regulation as bridge concepts. We start from a characterization of biological mechanisms in terms of constraints and focus on a specific type of mechanism, control mechanisms, that operate on other mechanisms on the basis of measurements of variables in the system and its environment. Control mechanisms are characterized by their own set of constraints that enable them to sense conditions, convey signals, and effect changes on constraints in the controlled mechanism. They thereby allow living organisms to adapt to internal and external variations and to coordinate their parts in such a manner as to maintain viability. Because living organisms contain a vast number of control mechanisms, a central challenge is to understand how they are themselves organized. With the support of examples from both unicellular and multicellular systems we argue that control mechanisms are organized heterarchically, and we discuss how this type of control architecture can, without invoking top-down and centralized forms of organizations, succeed in coordinating internal activities of organisms. (shrink)

Living organisms act as integrated wholes to maintain themselves. Individual actions can each be explained by characterizing the mechanisms that perform the activity. But these alone do not explain how various activities are coordinated and performed versatilely. We argue that this depends on a specific type of mechanism, a control mechanism. We develop an account of control by examining several extensively studied control mechanisms operative in the bacterium E. coli. On our analysis, what distinguishes a control mechanism from other mechanisms (...) is that it relies on measuring one or more variables, which results in setting constraints in the control mechanism that determine its action on flexible constraints in other mechanisms. In the most basic arrangement, the measurement process directly determines the action of the control mechanism, but in more complex arrangements signals mediate between measurements and effectors. This opens the possibility of multiple responses to the same measurement and responses based on multiple measurements. It also allows crosstalk, resulting in networks of control mechanisms. Such networks integrate the behaviors of the organism but also present a challenge in tailoring responses to particular measurements. We discuss how integrated activity can still result in differential, versatile, responses. (shrink)

BackgroundMinorities are an underrepresented population in clinical trials. A potential explanation for this underrepresentation could be lack of willingness to participate. The aim of our study was to evaluate willingness to participate in different hypothetical clinical research scenarios and to evaluate the role that predictors could have on the willingness of minorities to participate in clinical research studies.MethodsWe conducted a mixed-methods study at the Miami VA Healthcare system and included primary care patients with hypertension. We measured willingness to participate as (...) a survey of four clinical research scenarios that evaluated common study designs encountered in clinical research and that differed in degree of complexity. Our qualitative portion included comments about the scenarios.ResultsWe included 123 patients with hypertension in our study. Of the entire sample, ninety-three patients were minorities. Seventy per cent of the minorities were willing to participate, compared to 60 per cent of the non-minorities. The odds ratio of willingness to participate in simple studies was 0.58; 95 per cent CI 0.18–1.88 p=0.37 and the OR of willingness to participate in complex studies was 5.8; 95 per cent CI 1.10–1.31 p=0.03. In complex studies, minorities with low health literacy cited obtaining benefits as the most common reason to be willing to participate. Minorities who were not willing to participate, cited fear of unintended outcomes as the main reason.ConclusionsMinorities were more likely to be willing to participate in complex studies compared to non-minorities. Low health literacy and therapeutic misconception are important mediators when considering willingness to participate in clinical research. (shrink)

A presente entrevista serve como complemento ao artigo submetido com mesmo nome nesta edição. Ela trata de uma exposição da influencia tecnologica na vida das pessoas, e como essas ferramentas estão ligadas as novas sindromes.

O presente artigo toma como base o conceito da Sociedade do Cansaço de Byung Chul Han para tratar das novas síndromes do século XXI. A abordagem buscará problematizar as novas tecnologias e relaciona-las com o diagnóstico de Zigmunt Bauman sobre nossos tempos, de modo a analisar as variáveis técnicas introduzidas pelas novas tecnologias a partir da popularização da internet. O objetivo deste trabalho é demonstrar que os avanços conquistados pela indústria tecnológica e suas técnicas aplicadas ao uso de seus produtos, (...) produziu uma sociedade mais conectada, porém, mais individualizada, onde as relações se tornaram frágeis e novas síndromes passaram a acometer este novo mundo. Deste modo entenderemos os mecanismos de controle e os efeitos desta cultura massificada, onde as fronteiras se estreitaram, as diferenças se achataram e os vínculos e autonomia se perderam. (shrink)

En el presente ensayo se busca desarrollar una hipótesis que vincula la relación pedagógica con la relación política y su interacción para la construcción y reproducción de una lógica idéntica que atraviesa y sobrepasa diversos campos sociales. Esta hipótesis que relaciona el fundamento mismo de la educación con la metáfora del triángulo pedagógico y que identifica en ella una lógica de producción de la desigualdad hace repensar el planteo de la educación como derecho, sin antes poner en cuestión diversos elementos (...) que la fundamentan, en especial aquellos vinculados al concepto de transmisión. (shrink)

The purpose of this paper is less ambitious than its title might suggest, since it does not deal with everything that Plato has said on time and on eternity. Rather, it attempts to clarify some issues which have arisen in the controversy as to whether Parmenides or Plato was the first Western philosopher to grasp the notion of atemporal eternity. It is particularly concerned with some publications on the subject that have appeared within the last twelve years or so. G. (...) E. L. Owen, in a paper published in this journal, has defended his earlier interpretation that Parmenides discovered the notion of atemporal eternity. J. Whittaker for his part has contended that both Parmenides and Plato failed to grasp it, and would ascribe its discovery to some later thinker. Yet another scholar, G. Reale, believes that there is no essential difference between the position of Parmenides as reconstructed by Owen and others and that of Melissus. For Reale maintains that Melissus’ formula “it is and always was and always will be” does not exclude atemporality, that it means the same thing as the alleged tenseless ‘is’ predicated of Parmenides’ Being. (shrink)

Biological regulation is what allows an organism to handle the effects of a perturbation, modulating its own constitutive dynamics in response to particular changes in internal and external conditions. With the central focus of analysis on the case of minimal living systems, we argue that regulation consists in a specific form of second-order control, exerted over the core regime of production and maintenance of the components that actually put together the organism. The main argument is that regulation requires a distinctive (...) architecture of functional relationships, and specifically the action of a dedicated subsystem whose activity is dynamically decoupled from that of the constitutive regime. We distinguish between two major ways in which control mechanisms contribute to the maintenance of a biological organisation in response to internal and external perturbations: dynamic stability and regulation. Based on this distinction an explicit definition and a set of organisational requirements for regulation are provided, and thoroughly illustrated through the examples of bacterial chemotaxis and the lac-operon. The analysis enables us to mark out the differences between regulation and closely related concepts such as feedback, robustness and homeostasis. (shrink)

Despite numerous and increasing attempts to define what life is, there is no consensus on necessary and sufficient conditions for life. Accordingly, some scholars have questioned the value of definitions of life and encouraged scientists and philosophers alike to discard the project. As an alternative to this pessimistic conclusion, we argue that critically rethinking the nature and uses of definitions can provide new insights into the epistemic roles of definitions of life for different research practices. This paper examines the possible (...) contributions of definitions of life in scientific domains where such definitions are used most (e.g., Synthetic Biology, Origins of Life, Alife, and Astrobiology). Rather than as classificatory tools for demarcation of natural kinds, we highlight the pragmatic utility of what we call operational definitions that serve as theoretical and epistemic tools in scientific practice. In particular, we examine contexts where definitions integrate criteria for life into theoretical models that involve or enable observable operations. We show how these definitions of life play important roles in influencing research agendas and evaluating results, and we argue that to discard the project of defining life is neither sufficiently motivated, nor possible without dismissing important theoretical and practical research. (shrink)

Despite globalization a progressively increasing economic and financial concentration in the ‘cores’ of the world economy (e.g. EU) as well as the rise of new socioeconomic marginalization of peripheries (e.g. Maghreb and Mashraq) has been observed since the early 1980s. Marginalization has produced its own models of specialization in production which reflect in various countries and regions the needs of the ‘cores’ economy forces. A regional strategy for regional co-operation, so called co-development, is advanced to overcome the current economic and (...) social problems faced by marginalized regions in relation to world economic trends. (shrink)

O presente artigo tem como objetivo mostrar o novo status ontológico e fenomenológico daresponsabilidade a partir de uma releitura do animal na obra de Hans Jonas. Neste trabalho,sustentamos que a responsabilidade deve ser entendida como um degrau presente na escala dofenômeno vida. Por ser uma escala que acumula, conserva e compartilha as características de outrosseres, nos parece possível afirmar que a responsabilidade, mesmo que em estado latente, deve estargerminalmente prefigurada em outros seres vivos. Nosso problema de pesquisa coloca o seguintequestionamento: (...) se a responsabilidade está contida na escala de desenvolvimento e aptidões do ser, ede acordo com os pressupostos jonasianos, seguindo a lógica da biologia aristotélica, de que ascamadas mais baixas são conservadas nas superiores, seria possível pensar numa manifestação daresponsabilidade nos níveis mais baixos de tal escala? A fim de tentar responder nossa problemática enosso objetivo, seguiremos o seguinte caminho: num primeiro momento, apresentaremos como aliberdade é o conceito guia fundamental para interpretarmos o fenômeno vida, veremos que quandoJonas amplia tal conceito como sendo pertencente a todo ser, o autor provoca uma revolução ontológicana filosofia, causando uma ferida no antropocentrismo moderno, uma vez que até então, o conceito deliberdade era restrito a esfera humana; num segundo momento, analisaremos como os conceitos demovimento, percepção e sensação se tornaram características próprias do reino animal e como estesseparam o mundo vegetal do animal; por fim, num terceiro momento, defenderemos que na própria obrajonasiana existem certos conceitos que exprimem nossa tese de que a responsabilidade se manifesta deforma latente e germinal no âmbito animal, principalmente nos conceitos de alteridade e sentimento, queos animais têm para com seus próximos. (shrink)

Endocrinologists apply the idea of feedback loops to explain how hormones regulate certain bodily functions such as glucose metabolism. In particular, feedback loops focus on the maintenance of the plasma concentrations of glucose within a narrow range. Here, we put forward a different, organicist perspective on the endocrine regulation of glycaemia, by relying on the pivotal concept of closure of constraints. From this perspective, biological systems are understood as organized ones, which means that they are constituted of a set of (...) mutually dependent functional structures acting as constraints, whose maintenance depends on their reciprocal interactions. Closure refers specifically to the mutual dependence among functional constraints in an organism. We show that, when compared to feedback loops, organizational closure can generate much richer descriptions of the processes and constraints at play in the metabolism and regulation of glycaemia, by making explicit the different hierarchical orders involved. We expect that the proposed theoretical framework will open the way to the construction of original mathematical models, which would provide a better understanding of endocrine regulation from an organicist perspective. (shrink)

El uso de un conocimiento invariante para alcanzar propósitos intervencionistas o de política es comúnmente aceptado por los enfoques manipulabilistas. Sin embargo, dicho uso plantea dos problemáticas filosóficas que serán examinadas en el presente trabajo. El primer problema es ontológico, y refiere a la dificultad de encontrar genuinos factores causales estables en ciencias sociales. En este sentido, se mostrará que los fenómenos sociales no responden a una lógica de factores estables como los mecanismos o las «capacidades», sino que se adecúan (...) más a una lógica de «árboles de posibilidades” o «resultados de final abierto». El otro problema es de índole epistemológico y refiere a que, incluso si se encuentran contribuciones sociales estables, nada garantiza que dicha estabilidad prevalezca en el futuro. Diferentes tesis que avalan esta problemática serán examinadas, tales como la denominada «crítica de Lucas» o la «teoría del cisne negro». (shrink)

Despite numerous and increasing attempts to define what life is, there is no consensus on necessary and sufficient conditions for life. Accordingly, some scholars have questioned the value of definitions of life and encouraged scientists and philosophers alike to discard the project. As an alternative to this pessimistic conclusion, we argue that critically rethinking the nature and uses of definitions can provide new insights into the epistemic roles of definitions of life for different research practices. This paper examines the possible (...) contributions of definitions of life in scientific domains where such definitions are used most. Rather than as classificatory tools for demarcation of natural kinds, we highlight the pragmatic utility of what we call operational definitions that serve as theoretical and epistemic tools in scientific practice. In particular, we examine contexts where definitions integrate criteria for life into theoretical models that involve or enable observable operations. We show how these definitions of life play important roles in influencing research agendas and evaluating results, and we argue that to discard the project of defining life is neither sufficiently motivated, nor possible without dismissing important theoretical and practical research. (shrink)

En los últimos años han aparecido publicaciones que intentan generar un marco para la aplicación de conocimientos neurocognitivos para la resolución de problemáticas sociales. Bajo el mote de “ciencias de comportamiento”, este campo de estudios que se presenta como profundamente interdisciplinario se propone aportar herramientas para resolver diversas problemáticas sociales, mediante la dilucidación de los mecanismos subyacentes a la conducta humana y su posterior operacionalización en forma de políticas públicas. Enfocamos nuestra mirada en ciertos aspectos epistemológicos e ideológicos que subyacen (...) a estas iniciativas, en particular su conceptualización de la crisis climática como un problema a resolver mediante los avances de las ciencias cognitivas. Observamos, ejemplificamos y problematizamos una serie de premisas: la conducta del individuo como expresión terminal de un proceso “interno” en el cual el ambiente y por extensión lo “social” están subordinados en cuanto a su jerarquía explicativa; la simplificación de las problemáticas a resolver en términos de sesgos y limitaciones cognitivas, de modo tal que los objetivos de la intervención sean los comportamientos y decisiones de actores individuales; la apelación a la biología como sustento explicativo de los constructos psicológicos utilizados a través de narrativas adaptacionistas sobre el desarrollo de funcionalidades cognitivas innatas. Sostenemos que la generación y aplicación de los conocimientos en este tipo de iniciativas se inscribe en una línea ideológica marcada, según la cual las causas principales de la crisis climática no se hallan en las dinámicas y contradicciones del sistema socioeconómico vigente, sino en las de los sistemas cognitivos individuales. (shrink)