An elementary semistochastic model for cell cycle analysis is presented. Various independently generated experimental data sets are compared with the theory in which for the first time, a consistent consideration of non-proliferating cells has also been taken into account.

An elementary semistochastic model for cell cycle analysis is presented. Various independently generated experimental data sets are compared with the theory in which for the first time, a consistent consideration of non-proliferating cells has also been taken into account.

El título de este libro, al estar en plural, constituye de por sí una petición de principio. Se trata, pues, de descomponer el Tiempo en tiempos y dentro de ellos analizar lo que son las secuencias de carácter temporal. Porque sólo rompiendo la interesada confusión del Tiempo con los tiempos puede pensarse de una forma "otra", puede empezar a repensarse el enorme sinsentido de la Estructura que nos atrapa, ratonera del pensamiento que adora la Realidad.

This article aims to read feminist new materialisms (Barad), together with ‘postulated’ linguistic or cultural primacy of Queer Theory (Butler), to show how both are engaged in similar critical-ethical endeavours. The central argument is that the criticism of Barad and new materialisms misses Butler’s materialistic insights due to a narrow interpretation of Butler's alleged social-constructivist position. There is, therefore, a specific focus on where they both make similar ethical appeals. Moreover, the article relies on Adorno's negative dialectic to highlight an (...) interpretation of Barad and Butler as being part of the same dialectical movement, in which materialism and idealism fluctuate in their mutual criticisms, thus continuing the procession towards 'new knowledge' and emancipation, or freedom, through their motions back and forth. (shrink)

The book challenges the values of much of contemporary bioethics and health care policy by confronting their failure to secure the moral norms they seek to apply.

Provability, Computability and Reflection.

La figure de l’entrepreneur est aujourd’hui utilisée dans une grande variété de discours publics. Ce travail cherche à remonter à l’une des sources théoriques de la constitution de cette figure : la théorie de l’entrepreneur de Schumpeter (1911a et 1911b). Ce retour montre que Schumpeter, dans son contexte intellectuel et théorique, est amené à importer une anthropologie philosophique en économie, celle de Nietzsche, auteur largement lu dans l’Autriche du début du xxe siècle. En transposant, à l’intérieur de sa théorie économique, (...) certaines caractéristiques majeures du grand homme créatif nietzschéen dans la figure de l’entrepreneur, Schumpeter développe une explication originale de la nature dynamique du marché et de l’évolution économique. Néanmoins il importe aussi de Nietzsche une série d’ambiguïtés, notamment en ce qui concerne l’origine de l’exceptionnalité individuelle de l’entrepreneur, et plus particulièrement de sa puissance créatrice. Une seconde ambiguïté est très largement héritée, qui concerne l’extension du modèle de l’individu entrepreneur : constitue-t-il une théorie de l’action valable pour tous les individus ou uniquement pour un type d’individus particuliers? Comment concilier exceptionnalité de l’entrepreneur et norme d’un entreprenariat pour tous? La dernière partie de ce travail s’attache ainsi à explorer ces ambiguïtés, qui apparaissent chez Schumpeter et ses successeurs, notamment Israël Kirzner.Codes JEL : B13, B25, B31, B40. (shrink)

This is the first complete, one-volume English translation of the ancient Chinese text Xunzi, one of the most extensive, sophisticated, and elegant works in the tradition of Confucian thought. Through essays, poetry, dialogues, and anecdotes, the Xunzi articulates a Confucian perspective on ethics, politics, warfare, language, psychology, human nature, ritual, and music, among other topics. Aimed at general readers and students of Chinese thought, Eric Hutton’s translation makes the full text of this important work more accessible in English than ever (...) before. Named for its purported author, the Xunzi has long been neglected compared to works such as the Analects of Confucius and the Mencius. Yet interest in the Xunzi has grown in recent decades, and the text presents a much more systematic vision of the Confucian ideal than the fragmented sayings of Confucius and Mencius. In one famous, explicit contrast to them, the Xunzi argues that human nature is bad. However, it also allows that people can become good through rituals and institutions established by earlier sages. Indeed, the main purpose of the Xunzi is to urge people to become as good as possible, both for their own sakes and for the sake of peace and order in the world. In this edition, key terms are consistently translated to aid understanding and line numbers are provided for easy reference. Other features include a concise introduction, a timeline of early Chinese history, a list of important names and terms, cross-references, brief explanatory notes, a bibliography, and an index. (shrink)

An English language translation accompanies the original Greek text of Aristotle's book about the nature of the state, constitutions, revolutions, democracy, and oligarchy.

Film festivals have become key agents in the movie business, with major competitive festivals enjoying outstanding importance. Based on this assumption, this paper focuses on the example of Germany and asks to what extent the Berlin International Film Festival offers a venue for domestic films, and which types of filmmakers, in particular, benefit from this springboard and gatekeeping mechanism. More precisely, given the diverging interests confronting the Berlinale as a platform for the film community, a quantitative program analysis was conducted (...) of the festival’s most significant sections (Competition, Panorama, Forum, Generation, Perspective German Cinema, Lola@Berlinale) from 1980 to 2016. The findings demonstrate that even good-faith efforts to strengthen domestic filmmaking in regard to weight and diversity have hardly changed the power structures that underlie the curatorial decision-making process. Respectively, the share of national film productions has been stagnating for many years. Moreover, female and young filmmakers are still broadly underrepresented. (shrink)

The development of transplantation technology increasingly places before society a multitude of diverse, complex ethical and legal problems. The subject is the more complex because of the various divergent interests involved. There are the interests of the donor of organs, who has a right to protection of his legal position, and those of the patient in need of an often lifesaving organ. There are also the interests of the donor’s relatives, after his death, and those of the transplantation surgeons. The (...) international dimension of transplantation technology makes the picture even more complicated. Though this article is devoted to the European situation, the problems are similar all over the world. (shrink)

The development of transplantation technology increasingly places before society a multitude of diverse, complex ethical and legal problems. The subject is the more complex because of the various divergent interests involved. There are the interests of the donor of organs, who has a right to protection of his legal position, and those of the patient in need of an often lifesaving organ. There are also the interests of the donor’s relatives, after his death, and those of the transplantation surgeons. The (...) international dimension of transplantation technology makes the picture even more complicated. Though this article is devoted to the European situation, the problems are similar all over the world. (shrink)

Catastrophic risk raises questions that are not only of practical importance, but also of great philosophical interest, such as how to define catastrophe and what distinguishes catastrophic outcomes from non-catastrophic ones. Catastrophic risk also raises questions about how to rationally respond to such risks. How to rationally respond arguably partly depends on the severity of the uncertainty, for instance, whether quantitative probabilistic information is available, or whether only comparative likelihood information is available, or neither type of information. Finally, catastrophic risk (...) raises important ethical questions about what to do when catastrophe avoidance conflicts with equity promotion. (shrink)

"Using hundreds of examples from newsrooms large and small, author Ron F. Smith challenges readers to determine how they would face moral dilemmas on the job. Chapters evaluate the search for principles, accountability, truth and objectivity, errors and corrections, diversity, "faking" the news, reporters and their sources, privacy, the government watch, deception, compassion, the business of news, journalists and their communities, and financial concerns. New to this edition: a chapter on improving coverage of minorities, expanded discussion of broadcast journalism and (...) reporting on the Internet, and stories from recent front pages and TV news programs."--BOOK JACKET.Title Summary field provided by Blackwell North America, Inc. All Rights Reserved. (shrink)

First published in 2000. Routledge is an imprint of Taylor & Francis, an informa company.

First Published in 2000. Routledge is an imprint of Taylor & Francis, an informa company.

This study described the relationships between academic class and student moral sensitivity and reasoning and between curriculum design components for ethics education and student moral sensitivity and reasoning. The data were collected from freshman (n = 506) and senior students (n = 440) in eight baccalaureate nursing programs in South Korea by survey; the survey consisted of the Korean Moral Sensitivity Questionnaire and the Korean Defining Issues Test. The results showed that moral sensitivity scores in patient-oriented care and conflict were (...) higher in senior students than in freshman students. Furthermore, more hours of ethics content were associated with higher principled thinking scores of senior students. Nursing education in South Korea may have an impact on developing student moral sensitivity. Planned ethics content in nursing curricula is necessary to improve moral sensitivity and moral reasoning of students. (shrink)

A promise to do some action seems to create a binding obligation to do that action. And yet, paradoxically, an obligation seems not to be a fact that we can create or bring into existence; we can create an obligation only by creating or bringing into existence something else. The only way to avoid the paradox is to show that the act of promising creates something other than an obligation, which nonetheless binds us to perform the action in question. After (...) considering and rejecting various options such as the promisee's expectation and the promisor's resolve, Prichard locates the bindingness of a promise in a prior general promise, which allows the noises we make when promising to generate an obligation to perform the promised action. (shrink)

What are 'emotions'? This book offers a balanced survey of facts and theory.

Although the view dies hard that the poetry which Ovid wrote during his years in exile at Tomi consists largely of the ‘querulous and sycophantic’ complaints of a weak man unable to come to terms with a personal disaster, it has been recognized for many years that the Tristia and the Epistolae ex Ponto are not mere expressions of emotion but are as well thought out and constructed as any other of the doctus poeta's products. Of these poems, Tristia 2 (...) must be placed in a category by itself-if only because of its length and because it purports to be a plea by Ovid to Augustus, the man responsible for his exile, on the very practical matter of mitigating the sentence. (shrink)

Science Without Numbers caused a stir in 1980, with its bold nominalist approach to the philosophy of mathematics and science. It has been unavailable for twenty years and is now reissued in a revised edition with a substantial new preface presenting the author's current views and responses to the issues raised in subsequent debate.

To the question ‘What does it mean to act or to do something?’, replies that it is not easy to identify a common character in actions. Begins by examining the position of Cook Wilson, who maintains that ‘to do something’ means to originate, cause, or bring into existence, either directly or indirectly, some not yet existing state either in oneself or some other body. Although Prichard agrees that usually action involves causing something, he observes that causing a change is not (...) itself an activity. In moving one's hand, one performs that indefinable mental activity of willing some change. The movement of the hand is the effect of the action, not the action itself, a fact overlooked by thinkers like Locke. Turning to the nature of the desire behind one's willing, Prichard rejects the view that this desire is actually a desire for the change willed. Despite forceful objections, Prichard maintains that this desire is the desire for the willing of that change. (shrink)

In recent years many historians have rightly emphasised aggressive imperialism as a key element in Roman political life in the Middle and Late Republic. This has led to reconsideration of the significance of the ‘just war’ theory associated with the college of fetiales. ‘On the basis of this fetial law of the Roman people, it can be understood that no war is justified unless it is waged after compensation has been demanded , or the war has been announced in advance (...) and formally proclaimed.’ Earlier this century, scholars were happy to accept that this ‘fetial law’ implied that the Romans never initiated wars of aggression but fought only if they felt they were the aggrieved party. Scullard believed that ‘…in fact Roman religious law did not countenance wars of aggression designed to gain new territory’ ; for Tenney Frank, ‘ the Roman mos maiorum did not recognise the right of aggression or a desire for more territory as just causes for war. That the institution was observed in good faith for centuries there can be no doubt.’ Recent scholars have been more sceptical. Harris sees the activities of the fetiales primarily as a psychological mechanism for assuaging the guilt feelings which even Romans will have been unable to escape when initiating totally unjustified wars of aggression: ‘the significance of the fetial procedure for declaring war was solely psychological’. Other writers have gone further in stressing its mystificatory and propaganda function. Our scepticism about the efficacy of ‘fetial law’ in restraining the Romans' belligerence should be accompanied by a re-evaluation of our evidence regarding the fetiales and what they actually did. Such a re-evaluation will not affect our picture of the Romans of the Middle and Late Republic as aggressive and militaristic, but we may have to revise our views on how the fetiales fit into that picture. This paper makes no claim to analyse exhaustively every piece of evidence which might throw some light on the fetiales, let alone every interpretation to be found in the secondary literature; but it may be worthwhile to reconsider the main types of operations which the fetiales are said by our ancient sources to have been involved in. (shrink)

According to the orthodox treatment of risk preferences in decision theory, they are to be explained in terms of the agent's desires about concrete outcomes. The orthodoxy has been criticised both for conflating two types of attitudes and for committing agents to attitudes that do not seem rationally required. To avoid these problems, it has been suggested that an agent's attitudes to risk should be captured by a risk function that is independent of her utility and probability functions. The main (...) problem with that approach is that it suggests that attitudes to risk are wholly distinct from people's (non-instrumental) desires. To overcome this problem, we develop a framework where an agent's utility function is defined over chance propositions (i.e., propositions describing objective probability distributions) as well as ordinary (non-chance) ones, and argue that one should explain different risk attitudes in terms of different forms of the utility function over such propositions. (shrink)

Suppose that a decision-maker's aim, under certainty, is to maximise some continuous value, such as lifetime income or continuous social welfare. Can such a decision-maker rationally satisfy what has been called "continuity for easy cases" while at the same time satisfying what seems to be a widespread intuition against the full-blown continuity axiom of expected utility theory? In this note I argue that the answer is "no": given transitivity and a weak trade-off principle, continuity for easy cases violates the anti-continuity (...) intuition. I end the note by exploring an even weaker continuity condition that is consistent with the aforementioned intuition. (shrink)

Many philosophers think that we should use a lottery to decide who gets a good to which two persons have an equal claim but which only one person can get. Some philosophers think that we should save identified persons from harm even at the expense of saving a somewhat greater number of statistical persons from the same harm. I defend a principled way of justifying both judgements, namely, by appealing to the decreasing marginal moral value of survival chances. I identify (...) four desiderata that, I contend, any such justification should satisfy, and explain how my account meets these desiderata, unlike some previous accounts. (shrink)

The institution of slavery has served to perform different functions in different societies. The distinction between ‘closed’ and ‘open’ slavery can be a useful one: in some societies slavery is a mechanism for the permanent exclusion of certain individuals from political and economic privileges, while in others it has served precisely to facilitate the integration of outsiders into the community. ‘The African slave, brought by a foray to the tribe, enjoys, from the beginning, the privileges and name of a child, (...) and looks upon his master and mistress in every respect as his new parents… by care and diligence, he may soon become a master himself, and even more rich and powerful than he who led him captive.’ The model of an ‘open’ slavery implies that service as a slave is not a state to which a person is permanently, let alone ‘naturally’, assigned, but more akin to an age-grade. A parallel might be domestic or agricultural service as it was practised in much of Europe until this century — a period spent serving in another household after childhood and prior to marriage. A Roman slave, on formal manumission, joined the community of citizens. To what extent ought we therefore to succumb to the temptation to see slavery at Rome — in contrast to the Greek world — in terms of the ideal type of a ‘process of integration’? In a noted article on ‘Die Freilassung von Sklaven und die Struktur der Sklaverei in der römischen Kaiserzeit’ , G. Alföldi argued that in the Roman Empire slavery was an ‘Übergangszustand’ , a transitional state which ultimately gave most slaves a recognised if not a fully equal place as members of the Roman citizen community. (shrink)

This volume is a wonderful introduction to Foucault and a testimony to the deep humanity of the man himself.

This paper argues that proper functions are proximal functions. In other words, it rejects the notion that there are distal biological functions – strictly speaking, distal functions are not functions at all, but simply beneficial effects normally associated with a trait performing its function. Once we rule out distal functions, two further positions become available: dysfunctions are simply failures of proper function, and pathological conditions are dysfunctions. Although elegant and seemingly intuitive, this simple view has had surprisingly little uptake in (...) the literature. Indeed, our position departs from that of almost every theorist who has engaged with the issue at any depth. We start by presenting three arguments for the position that proper functions are proximal: one from the specificity of functions, one from their relation to intervention, and one from their relation to pathology. We then consider two case studies evidencing the trouble that accepting distal functions causes for philosophical reflection on the nature of pathological conditions. Finally, we anticipate and respond to three objections: that there can be failure of function without dysfunction; that our account is unacceptably revisionary in respect of normal function-talk; and that our thesis over-generalises from a narrow set of cases. (shrink)