‘Dira’ is a novel experimental paradigm to record combinations of behavioural and metacognitive measures for the creative process. This task allows assessing chronological and chronometric aspects of the creative process directly and without a detour through creative products or proxy phenomena. In a study with 124 participants we show that (a.) people spend more time attending to selected versus rejected potential solutions, (b.) there is a clear connection between behavioural patterns and self-reported measures, (c.) the reported intensity of (...) Eureka experiences is a function of interaction time with potential solutions, and (d.) experiences of emerging solutions can happen immediately after engaging with a problem, before participants explore all potential solutions. The conducted study exemplifies how ‘Dira’ can be used as an instrument to narrow down the moment when solutions emerge. We conclude that the ‘Dira’ experiment is paving the way to study the process, as opposed to the product, of creative problem solving. (shrink)

Why games? How could anyone consider action games an experimental paradigm for Cognitive Science? In 1973, as one of three strategies he proposed for advancing Cognitive Science, Allen Newell exhorted us to “accept a single complex task and do all of it.” More specifically, he told us that rather than taking an “experimental psychology as usual approach,” we should “focus on a series of experimental and theoretical studies around a single complex task” so as to demonstrate (...) that our theories of human cognition were powerful enough to explain “a genuine slab of human behavior” with the studies fitting into a detailed theoretical picture. Action games represent the type of experimental paradigm that Newell was advocating and the current state of programming expertise and laboratory equipment, along with the emergence of Big Data and naturally occurring datasets, provide the technologies and data needed to realize his vision. Action games enable us to escape from our field's regrettable focus on novice performance to develop theories that account for the full range of expertise through a twin focus on expertise sampling and longitudinal studies of simple and complex tasks. (shrink)

The contents of our conscious mind can seem unpredictable, whimsical, and free from external control. When instructed to attend to a stimulus in a work setting, for example, one might find oneself thinking about household chores. Conscious content thus appears different in nature from reflex action. Under the appropriate conditions, reflexes occur predictably, reliably, and via external control. Despite these intuitions, theorists have proposed that, under certain conditions, conscious content resembles reflexes and arises reliably via external control. We introduce the (...) Reflexive Imagery Task, a paradigm in which, as a function of external control, conscious content is triggered reliably and unintentionally: When instructed to not subvocalize the name of a stimulus object, participants reliably failed to suppress the set-related imagery. This stimulus-elicited content is considered ‘high-level’ content and, in terms of stages of processing, occurs late in the processing stream. We discuss the implications of this paradigm for consciousness research. (shrink)

Change and variation, while inherent to language, might be seen as running counter to human communicative needs. However, variation also gives language the power to convey reliable indexical information about the speaker. This has been argued to play a significant role in allowing the establishment of large communities based on cooperative exchange , although there has been little experimental investigation of the hypothesis. Here I present a preliminary study intended to help fill this gap. Participants played an online team (...) game in which they negotiated anonymously for resources using an artificial language. Players succeeded in using linguistic cues to distinguish between their teammates and their opponents, and displayed between-team variation in the use of the language. (shrink)

The characterisation of normal stem cells and cancer stem cells uses the same paradigm. These cells are isolated by a fluorescence‐activated cell sorting step and their stemness is assayed following implantation into animals. However, differences exist between these two kinds of stem cells. Therefore, the translation of the experimental procedures used for normal stem cell isolation into the research field of cancer stem cells is a potential source of artefacts. In addition, normal stem cell therapy has the objective (...) of regenerating a tissue, while cancer stem cell‐centred therapy seeks the destruction of the cancer tissue. Taking these differences into account is critical for anticipating problems that might arise in cancer stem cell‐centred therapy and for upgrading the cancer stem cell paradigm accordingly. (shrink)

Researchers, including Boyer & Petersen (B&P), commonly use experimental economic studies to draw their conclusions. These studies conventionally strip away context and present participants only with abstract rules. Because context is a strictly necessary component of the decision-making process, it is not clear that inferences about high-level folk psychological concepts (e.g., rationality) can be drawn from decontextualized economic games.

_Animal Experimentation: Working Towards a Paradigm Change_ critically appraises current animal use in science and discusses ways in which we can contribute to a paradigm change towards human-biology based approaches.

This paper assumes that there is a distinction between empirical and non-empirical science. It also assumes that empirical science has two complementary parts, namely, theorization and experimentation. The paper focuses strictly on the experimental aspect of science. It is a call for reformation in African experimental science. Following a deep historical understanding of the revolution that brought about experimental philosophy this paper admits that magic was the mother, not just the “bastard sister” of empirical science. It uncovers (...) the fact that magic added the dimension of experimentation to science. This paper somewhat maintains that most of the ideas presented by some African scholars contain vestiges of the magical tradition in them. Even though this might not be a flaw by any reasonable standard, the paper still argues that there is a genuine need to separate magic from science, if we ever crave for any form of material/physical progress in Africa. I insist that the thrust of the call for paradigm shift in this paper is centered basically on experimentation. The issue of theoretical entities was introduced only to the extent such entities enhance experimental realism in the practice of African science. Of course, reformation can equally take place at the level of scientific theorization, but that is strictly beyond the scope of this paper. The fact is that those who are versed on the issues of experimentation should begin to get more focused on that aspect; and those who are given to theorization should settle with the formulation of well-structured theories. Time has indeed come for us to properly streamline our thoughts and make progress in the direction of African experimental science. In making this clarion call, we adopted a combined approach of hermeneutics and analysis. Keywords : Magic, African science, experimental science, paradigm, African thought. (shrink)

Descriptive accounts of the nature of explanation in neuroscience and the global goals of such explanation have recently proliferated in the philosophy of neuroscience and with them new understandings of the experimental practices of neuroscientists have emerged. In this paper, I consider two models of such practices; one that takes them to be reductive; another that takes them to be integrative. I investigate those areas of the neuroscience of learning and memory from which the examples used to substantiate these (...) models are culled, and argue that the multiplicity of experimental protocols used in these research areas presents specific challenges for both models. In my view, these challenges have been overlooked largely because philosophers have hitherto failed to pay sufficient attention to fundamental features of experimental practice. I demonstrate that when we do pay attention to such features, evidence for reduction and integrative unity in neuroscience is simply not borne out. I end by suggesting some new directions for the philosophy of neuroscience that pertain to taking a closer look at the nature of neuroscientific experiments. (shrink)

Cognitive processing in psychology and semiotics are compared in relation to language processing and memory.Active reconstruction in memory is postulated, as well as the representation of whole messages as signs. The paradigm, then, is based on the study of active reconstruction of verbal messages from their semiotic representations in memory. Differences between original and reconstructed messages are used as dimension of empirical study in the paradigm. Research findings are cited in support of this approach.

This chapter evaluates the defective verbal paradigms in the Hungarian language. The first section of the chapter provides an overview of the defectiveness in Hungarian, with emphasis on the systematic, phonotactically motivated defectiveness of the paradigms of some verbal stems. The aim of this section is to be as theoretically neutral and descriptive as possible to facilitate a good comparison with other types of defectiveness in other languages. The second section of the chapter discusses the results of the experiments which (...) are conducted in order to determine the various aspects of the defectiveness in the verbal paradigm. Some of the aspects tested include: the gap locations such as the occurrence and variation of forms in other designated cells of the verbal paradigm, and the correlations between the occurrence of forms in some designated cells; and the gap properties such as the differences in the classification of some verb stems into various stem-classes, and the range of variation exhibited by the forms that native Hungarian speakers accept as fill-ins for the gaps that are present in the paradigms of the defective verbs. (shrink)

Jonathan Weinberg (2007) has argued that we should not appeal to intuition as evidence because it cannot be externally corroborated. This paper argues for the normative claim that Weinberg’s demand for external corroboration is misguided. The idea is that Weinberg goes wrong in treating philosophical appeal to intuition analogous to the appeal to evidence in the sciences. Traditional practice is defended against Weinberg’s critique with the argument that some intuitions are true simply in virtue of being intuited by the majority (...) of people. The argument proceeds by way of examining a paradigm case, Putnam’s Twin Earth. (shrink)

We examine the philosophical disputes among computer scientists concerning methodological, ontological, and epistemological questions: Is computer science a branch of mathematics, an engineering discipline, or a natural science? Should knowledge about the behaviour of programs proceed deductively or empirically? Are computer programs on a par with mathematical objects, with mere data, or with mental processes? We conclude that distinct positions taken in regard to these questions emanate from distinct sets of received beliefs or paradigms within the discipline: – The rationalist (...) paradigm, which was common among theoretical computer scientists, defines computer science as a branch of mathematics, treats programs on a par with mathematical objects, and seeks certain, a priori knowledge about their ‘correctness’ by means of deductive reasoning. – The technocratic paradigm, promulgated mainly by software engineers and has come to dominate much of the discipline, defines computer science as an engineering discipline, treats programs as mere data, and seeks probable, a posteriori knowledge about their reliability empirically using testing suites. – The scientific paradigm, prevalent in the branches of artificial intelligence, defines computer science as a natural (empirical) science, takes programs to be entities on a par with mental processes, and seeks a priori and a posteriori knowledge about them by combining formal deduction and scientific experimentation. We demonstrate evidence corroborating the tenets of the scientific paradigm, in particular the claim that program-processes are on a par with mental processes. We conclude with a discussion in the influence that the technocratic paradigm has been having over computer science. (shrink)

The redundant-signals paradigm (RSP) is designed to investigate response behavior in perceptual tasks in which response-relevant targets are defined by either one or two features, or modalities. The common finding is that responses are speeded for redundantly compared to singly defined targets. This redundant-signals effect (RSE) can be accounted for by race models if the response times do not violate the race model inequality (RMI). When there are violations of the RMI, race models are effectively excluded as a viable (...) account of the RSE. The common alternative is provided by co-activation accounts, which assume that redundant target signals are integrated at some processing stage. However, ‘co-activation’ has mostly been only indirectly inferred and the accounts have only rarely been explicitly modeled; if they were modeled, the RSE has typically been assumed to have a decisional locus. Yet, there are also indications in the literature that the RSE might originate, at least in part, at a non-decisional or motor stage. In the present study, using a distribution analysis of sequential-sampling models (ex-Wald and Ratcliff Diffusion model), the locus of the RSE was investigated for two bimodal (audio-visual) detection tasks that strongly violated the RMI, indicative of substantial co-activation. Three model variants assuming different loci of the RSE were fitted to the quantile reaction time proportions: a decision, a non-decision, and a combined variant both to vincentized group as well as individual data. The results suggest that for the two bimodal detection tasks, co-activation has a shared decisional and non-decisional locus. These findings point to the possibility that the mechanisms underlying the RSE depend on the specifics (task, stimulus, conditions, etc.) of the experimental paradigm. (shrink)

This study provides data for a behavioral paradigm to resolve the free will issue in psychological terms. As predicted, college students selecting among many alternative responses consistently selected according to experimental set, environmental conditions, past experiences and other unknown factors. These explained and unexplained causal factors supplement one another and make varying relative contributions to different behaviors - the Principle of Behavioral Supplementarity. The more psychologically remote the causal factors, the greater proportion of unexplained ones relative to explained (...) ones - the Principle of Remote Antecedence. Both the causal categories can be conceptualized in the incompatible terms of reductionism or intentionality, depending upon the dissociated belief state of the observer - the Principle of Behavioral Complementarity. Ordinarily, on utilitarian grounds, behaviors with psychologically contiguous antecedents are best conceptualized in a reductionistic belief state, and behaviors with remote antecedents are best conceptualized in an intentional belief state. (shrink)

Introduction: Traditionally, empathy has been studied from two main perspectives: the theory-theory approach and the simulation theory approach. These theories claim that social emotions are fundamentally constituted by mind states in the brain. In contrast, classical phenomenology and recent research based on enactive theories consider empathy as the basic process of contacting others’ emotional experiences through direct bodily perception and sensation. Objective: This study aims to enrich knowledge of the empathic experience of pain by using an experimental phenomenological method. (...) Method: Implementing an experimental paradigm used in affective neuroscience, we exposed 28 healthy adults to a video of sportspersons suffering physical accidents while practicing extreme sports. Immediately after watching the video, each participant underwent a phenomenological interview to gather data on embodied, multi-layered dimensions (bodily sensations, emotions, and motivations) and temporal aspects of empathic experience. We also performed quantitative analyses of the phenomenological categories. Results: Experiential access to the other person’s painful experience involves four main-themes. Bodily resonance: participants felt a multiplicity of bodily, affective, and kinesthetic sensations. Attentional focus: some participants centered their attention more on their own personal discomfort and sensations of rejection, while others on the pain and suffering experienced by the sportspersons. Kinesthetic motivation: some participants experienced the feeling in their bodies to avoid or escape from watching the video, while others experienced the need to help the sportspersons avoid suffering any injury while practicing extreme sports. Temporality of experience: participants witnessed temporal fluctuations in their experiences, bringing intensity changes in their bodily resonance, attentional focus, and kinesthetic motivation. Finally, two experiential structures were found: one structure is self-centered empathic experience, characterized by bodily resonance, attentional focus centered on the participant’s own experience of seeing the sportsperson suffering, and self-protective kinesthetic motivation; the other structure is other-centered empathic experience, characterized by bodily resonance, attentional focus centered on the sportsperson, and prosocial kinesthetic motivation to help them. Discussion: We show how phenomenological data may contribute to comprehending empathy for pain in social neuroscience. In addition, we address the phenomenological aspect of the enactive approach to the three dimensions of embodiment of human consciousness, especially the intersubjective dimension. Also, based on our results, we suggest an extension of the enactive theory for non-interactive social experience. (shrink)

Until recently, experimental philosophy has been associated with the questionnaire-based study of intuitions; however, experimental philosophers now adapt a wide range of empirical methods for new philosophical purposes. New methods include paradigms for behavioural experiments from across the social sciences as well as computational methods from the digital humanities that can process large bodies of text and evidence. This book offers an accessible overview of these exciting innovations. The volume brings together established and emerging research leaders from several (...) areas of experimental philosophy to explore how new empirical methods can contribute to philosophical debates. Each chapter presents one or several methods new to experimental philosophy, demonstrating their application in a key area of philosophy and discussing their strengths and limitations. Methods covered include eye tracking, virtual reality technology, neuroimaging, statistical learning, and experimental economics as well as corpus linguistics, visualisation techniques and data and text mining. The volume explores their use in moral philosophy and moral psychology, epistemology, philosophy of science, metaphysics, philosophy of language, philosophy of mind and the history of ideas. Methodological Advances in Experimental Philosophy is essential reading for undergraduates, graduate students and researchers working in experimental philosophy. (shrink)

In many areas of the social and behavioral sciences, the nature of the experiments and theories that best capture the underlying constructs are themselves areas of active inquiry. Integrative experiment design risks being prematurely exploitative, hindering exploration of experimental paradigms and of diverse theoretical accounts for target phenomena.

It appears that consciousness science is progressing soundly, in particular in its search for the neural correlates of consciousness. There are two main approaches to this search, one is content-based (focusing on the contrast between conscious perception of, e.g., faces vs. houses), the other is state-based (focusing on overall conscious states, e.g., the contrast between dreamless sleep vs. the awake state). Methodological and conceptual considerations of a number of concrete studies show that both approaches are problematic: the content-based approach seems (...) to set aside crucial aspects of consciousness; and the state-based approach seems over-inclusive in a way that is hard to rectify without losing sight of the crucial conscious-unconscious contrast. Consequently, the search for the neural correlates of consciousness is in need of new experimental paradigms. (shrink)

Humans are fundamentally social and tend to create emergent organizations when interacting with each other; from dyads to families, small groups, large groups, societies and civilizations. The study of the neuronal substrate of human social behavior is currently gaining momentum in the young field of social neuroscience. Hyperscanning is a neuroimaging technique by which we can study two or more brain simultaneously while participants interact with each other. The aim of this article is to discuss several factors that we deem (...) important in designing hyperscanning experiments. We first review hyperscanning studies performed by means of electroencephalography (EEG) that have been relying on a continuous interaction paradigm. Then, we provide arguments for favoring ecological paradigms, for studying the emotional component of social interactions and for performing longitudinal studies, the last two aspects being largely neglected so far in the hyperscanning literature despite their paramount importance in social sciences. Based on these premises we argue that music performance is a suitable experimental setting for hyperscanning and that for such studies EEG is an appropriate choice as neuroimaging modality. (shrink)

This essay focuses on the meaning that the term “experimental” acquires within spiritualism during the second half of the nineteenth century. It builds upon Paul Janet’s notions of “experience” and “experimentation” in psychology, by stressing the role of physiology and pathology in his reflection. Regardless of the role the concept of “experimentalism” took on in Victor Cousin’s psychology, which arguably indicated more an “internal affection” than actual experimentation, in Janet’s spiritualism the term regains its original meaning of empirical verification. (...) Janet highlights the importance of madness to the development of a new psychological paradigm that could reconcile philosophy and medicine, reason and experience, by taking up pathology as a form of natural and indirect experimentation. (shrink)

Contemporary philosophers nearly unanimously endorse knowledge reliabilism, the view that knowledge must be reliably produced. Leading reliabilists have suggested that reliabilism draws support from patterns in ordinary judgments and intuitions about knowledge, luck, reliability, and counterfactuals. That is, they have suggested a proto-reliabilist hypothesis about “commonsense” or “folk” epistemology. This paper reports nine experimental studies (N = 1262) that test the proto-reliabilist hypothesis by testing four of its principal implications. The main findings are that (a) commonsense fully embraces the (...) possibility of unreliable knowledge, (b) knowledge judgments are surprisingly insensitive to information about reliability, (c) “anti-luck” intuitions about knowledge have nothing to do with reliability specifically, and (d) reliabilists have mischaracterized the intuitive counterfactual properties of knowledge and their relation to reliability. When combined with the weakness of existing arguments for reliabilism and the recent emergence of well supported alternative views that predict the widespread existence of unreliable knowledge, the present findings are the final exhibit in a conclusive case for abandoning reliabilism in epistemology. I introduce an alternative theory of knowledge, abilism, which out-performs reliabilism and well explains all the available evidence. (shrink)

De Neys is right to criticize the exclusivity assumption in dual-process theories, but he misses the original sin underlying this assumption, which his working model continues to share. Conflict paradigms, in which experimenters measure how one cognitive process interferes (or does not interfere) with another, license few inferences about how the interfered-with process works on its own.

The imminent deployment of autonomous vehicles requires algorithms capable of making moral decisions in relevant traffic situations. Some scholars in the ethics of autonomous vehicles hope to align such intelligent systems with human moral judgment. For this purpose, studies like the Moral Machine Experiment have collected data about human decision-making in trolley-like traffic dilemmas. This paper first argues that the trolley dilemma is an inadequate experimental paradigm for investigating traffic moral judgments because it does not include agents’ character-based (...) considerations and is incapable of facilitating the investigation of low-stakes mundane traffic scenarios. In light of the limitations of the trolley paradigm, this paper presents an alternative experimental framework that addresses these issues. The proposed solution combines the creation of mundane traffic moral scenarios using virtual reality and the Agent-Deed-Consequences (ADC) model of moral judgment as a moral-psychological framework. This paradigm shift potentially increases the ecological validity of future studies by providing more realism and incorporating character considerations into traffic actions. (shrink)

In this paper I discuss some of the criteria that are widely used in the linguistic and philosophical literature to classify an aspect of meaning as either semantic or pragmatic. With regards to the case of scalar implicature (e.g. some Fs are G implying that not all Fs are G), these criteria are not ultimately conclusive, either in the results of their application, or in the interpretation of the results with regards to the semantics/pragmatics distinction (or in both). I propose (...) a psychologically relevant criterion, that of the primary or secondary role of context. This criterion applies to sub-personal processes that derive the interpretation of a scalar term rather than to the eventual interpretation of the term, and there exist well-established experimental paradigms that can generate quantitative data. I present recent studies on scalar implicature which employ such off-line and real-time paradigms, aiming to demonstrate how research on the semantics/pragmatics distinction can benefit from experimental investigation. (shrink)

Contrasting conditions with and without conscious experience has served consciousness research well. However, research based on this simple contrast has led to controversies about the neural basis of conscious experience. One key reason for these ongoing debates seems to be that the simple contrast between conditions with and without consciousness is not specific for unraveling the neural basis of conscious experience, but rather also leads to other processes that precede or follow it. Acknowledging this methodological problem implies that some of (...) the previous research findings about the neural underpinnings of conscious experience are actually reflecting the prerequisites and consequences rather than the direct correlates of conscious perception. Thus, it is required to re-evaluate the previous results to find out which of them are telling us anything about the neural basis of consciousness. But first and foremost, to overcome this methodological problem we need new experimental paradigms that go beyond the simple contrastive analysis or find the ways how some older but well forgotten paradigms may foster a new look at this emerging problem. Accordingly, this research topic is looking for empirical and theoretical contributions that: 1) envision new and suitable experimental approaches to study consciousness that are free from the limitations of the simple contrastive analysis; 2) provide empirical data that help to separate the neural correlates of conscious experience from the prerequisites and consequences of it; 3) help to re-assess previous research findings about the neural correlates of conscious perception in the light of the methodological problems with the traditional contrastive analysis. We hope that the theoretical insights and experimental approaches collected within this Research Topic help us to gain a more refined understanding of the neural basis of conscious experience. (shrink)

The relevance of inner speech for human psychology, especially for higher-order cognitive functions, is widely recognized. However, the study of the phenomenology of inner speech, that is, what it is like for a subject to experience internally speaking his/her voice, has received much less attention. This study explores the subjective experience of inner speech through empathy for pain paradigm. To this end, an experimental phenomenological method was implemented. Sixteen healthy subjects were exposed to videos of sportswomen/sportsmen having physical (...) accidents practicing extreme sports. Immediately after the exposure to the stimuli, a phenomenological interview was conducted to gather data about bodily sensations, emotions, motivations, and inner speech of watching other people’s accidents. Participant’s inner speech expresses concern about the consequences the accident could generate to the sportswomen/sportsmen or about the participants themselves. Simultaneously, participants’ inner speech happened with negative emotional feelings, many sensations distributed throughout their bodies, and a felt knowledge coming from a meaningful but pre-reflective and pre-verbal bodily dimension. Our findings show that inner speech in empathy is not merely a psycholinguistic process or high-order cognitive function, but rather it is a complex experience that occurs deeply related to meaningful emotions, bodily sensations, and an implicit, somatically felt knowledge. (shrink)

Identification of propositions as the core of attitudes and beliefs (De Houwer, 2014) has resulted in the development of implicit measures targeting personal evaluations of complex sentences (e.g., the IRAP or the RRT). Whereas their utility is uncontested, these paradigms are subject to limitations inherent in their block based design, such as allowing assessment of only a single belief at a time. We introduce the Propositional Evaluation Paradigm (PEP) for assessment of multiple propositional beliefs within a single experimental (...) block. Two experiments provide first evidence for the PEP’s validity. In Experiment 1 endorsement of racist beliefs measured with the PEP was related to criterion variables such as explicit racism assessed via questionnaire and indicators of behavioral tendencies. Experiment 2 indicates that the PEP’s implicit racism scores may predict actual behavior over and above explicit, self-report measures. Finally, Experiment 3 tested the PEP's applicability in the domain of hiring discrimination. Whereas general PEP based gender stereotypes were not related to hiring bias, results suggest a possible role of female stereotypes in hiring discrimination. In the context of these findings, we discuss both the potential and possible challenges in adopting the PEP to different beliefs. In sum, these initial findings suggest that the PEP may offer researchers a reliable and easily administrable option for the indirect assessment of propositional evaluations. (shrink)

Epiphenomenalism is the thesis that though physical events may cause mental events, those mental events never cause physical events. In this paper, I will be concerned with the claim that our thoughts, intentions, and awareness play no causal role in producing actions. Though epiphenomenalism has been defended with a priori philosophical arguments, the majority of the support that it has gained in recent years has come from advances in neuroscience. At the center of these experiments is the Libet paradigm (...) that aims to show that our actions are initiated by unconscious brain processes prior to our awareness of the intention or decision to perform the corresponding actions. It has been widely suggested that these studies support the view that consciousness is epiphenomenal, and if Libet-style experiments support this conclusion, the results have direct implications for free will. I argue by way of a dilemma that any study that relies on reports of subjects’ awareness in its methodology cannot be used to support epiphenomenalism because the experimenters would have to rule out the possibility that consciousness plays a causal role in order to do so. (shrink)

This paper concentrates on a debate over dispersion in the second half of the 1830s, in which both sides utilized the same set of experimental data to test a proposed wave account of dispersion, but could not agree on how these data should be used. The conflict regarding experimental data was caused by differences in instruments. In the debate, optical instruments in many ways functioned like paradigms, shaping scientists' opinions. Instruments also led the debate into an impasse, because (...) no apparatus was available for the necessary experimental replication. Because of unreconcilable differences regarding experimental evidence, the wave theory's failure in explaining dispersion did not become an obstacle to its acceptance. (shrink)

I attempt to characterize the relationship of classical experimental embryology (CEE) and molecular developmental biology and compare it to the much-discussed case of classical genetics. These sciences are treated here as discovery practices rather than as definitive forms of knowledge. I first show that CEE had some causal knowledge and hence was able to answer specific why?-questions. A paradigm was provided by the case of eye induction, perhaps CEE’s greatest success. The case of the famous Spemann-Mangold organizer is (...) more difficult. I argue that before the advent of molecular biology, knowledge of its causal role in development was very limited. As a result, there was no functional definition of the concept of organizer. I argue that, like the classical gene concept, it is best viewed as an operational concept. This means that an account of reduction such as Kim’s functional reduction, which is still a mainstay in scientific metaphysics, cannot work in these cases. Nonetheless, again like in the classical gene case, the operational concepts of CEE played an important heuristic role in the discovery of molecules involved in morphogenesis and cell differentiation. This was made possible by what I call inter-level investigative practices. These are practices that combine experimental manipulations targeting two (or more) different levels. I conclude that the two sciences are more closely related via their experimental practices than by any inter-level explanatory relations. (shrink)

High levels of somatic symptom distress represent a core component of both mental and physical illness. The exact aetiology and pathogenesis of this transdiagnostic phenomenon remain largely unknown. The Affective Picture Paradigm (APP) represents an innovative experimental paradigm to study somatic symptom distress. Based on the HiTOP framework and a population-based sampling approach, associations between facets of somatic symptom distress and symptoms induced by the APP were explored in two studies (N1 = 201; N2 = 254) using (...) structural equation bi-factor models. Results showed that the APP effect was significantly positively correlated with general somatic symptom distress (PHQ-15, HiTOP), cardio-respiratory symptoms (PHQ-15), as well as difficulties identifying feelings. In conclusion, negative affective cues in the APP can elicit somatic symptoms, particularly in people with higher levels of somatic symptom distress. Difficulties identifying feelings might contribute to this phenomenon. Results are compatible with a predictive processing account of somatic symptom perception. (shrink)

Clinical guidelines now recommend hormonal and surgical interven­tions together with social affirmation for children who experience a gender identity that is discordant with their biological sex. However, fundamental questions regarding the safety, efficacy, and ethics of these approaches remain unanswered. There is an urgent need for high-quality research to establish the overall risks and benefits of the current treatment paradigm. While acknowledging the complexity of the problem, competing interests, and logistical challenges, ethical imperatives and acceptable boundaries for scientific investigation (...) can be set by considering the ultimate good of both the individual person and society as a whole. Within established guidelines for human experimentation, alternative approaches to treatment of gender dysphoria in children can be explored without compromising the dignity and bodily integrity of affected individuals. (shrink)

Since the publication of Premack and Woodruff’s classic paper introducing the notion of a ‘theory of mind’ :515–526, 1978), interdisciplinary research in social cognition has witnessed the development of theory–theory, simulation theory, hybrid approaches, and most recently interactionist and perceptual accounts of other minds. The challenges that these various approaches present for each other and for research in social cognition range from adequately defining central concepts to designing experimental paradigms for testing empirical hypotheses. But is there any approach that (...) promises to dominate future interdisciplinary research in social cognition? Is social cognition witnessing a gradual paradigm shift where hitherto grounding notions such as theory of mind are no longer viewed as explanatorily necessary? Or have we simply lost our way in attempting to devise adequate experimental setups that could sway the debate in favour of one of the contending accounts? This special issue addresses these questions in an attempt to discover what the future holds for interdisciplinary research in social cognition. (shrink)