Recent reports of CRISPR/Cas9 genome editing in parasitic helminths open up new avenues for research on these dangerous pathogens. However, the complex morphology and life cycles inherent to these parasites present obstacles for the efficient application of CRISPR/Cas9‐targeted mutagenesis. This is especially true with the trematode flukes where only modest levels of gene mutation efficiency have been achieved. Current major challenges in the application of CRISPR/Cas9 for study of parasitic worms thus lie in enhancing gene mutation efficiency and overcoming issues (...) involved in host passage so that mutated parasites survive. Strategies developed for CRISPR/Cas9 studies on Caenorhabditis elegans, protozoa and mammalian cells, including novel delivery methods, the choice of selectable markers, and refining mutation precision represent novel tactics whereby these impediments can be overcome. Furthermore, employing CRISPR/Cas9‐mediated gene drive to interfere with vector transmission represents a novel approach for the control of parasitic worms that is worthy of further exploration. (shrink)

We examine whether and how CEO foreign experience affects firm’s green innovation. Using a sample of Chinese public companies and hand-collected CEO foreign experience data, we document a positive association between CEO foreign experience and corporate green innovation. Furthermore, consistent with the view that CEOs with foreign experience would play a more significant role when provided with more resources, we find that the positive relationship is more pronounced in less financially constrained firms, in state-owned enterprises, and in less competitive industries. (...) Additional analyses indicate that enhanced environmental ethics and general competency are two potential mechanisms through which CEO foreign experience affects corporate green innovation. Finally, we find that CEO foreign experience is positively related to green innovation quality and internationalization. Collectively, these findings suggest that CEO foreign experience is a significant factor for corporate green innovation in emerging markets. (shrink)

本书对自组织理论进行综合性研究,并探讨了关于自然界自组织演化的自然图景和自然观,关于自然科学自组织演化的科学图景和科学观。.

Abstract:With the development of literati gardens during the Ming dynasty (1368–1644), the layout and design level of gardens reached an unprecedented height. As the representative of Suzhou gardens, The Humble Administrator's Garden (Zhuozhengyuan, 拙政园, 1530) has unique natural conditions and mature garden design, and its water management art is particularly exquisite. The best-preserved graphic information of The Humble Administrator's Garden are the poems and paintings by Wen Zhengming (文徵明, 1470–1559), including Thirty-One Scenes of The Humble Administrator's Garden (拙政园三十一景图, 1533), thirty (...) landscape poems, and the biography Wang's Humble Administrator's Garden (王氏拙政园记, 1533). As the research object, this article aims to restore the image of The Humble Administrator's Garden by analyzing the water scene of the garden, summarizing its water technique and art, and extracting "Source of inflowing water" (为有源头活水来), "Esteem the mountain, revere the water, imitate the heaven and earth" (敬山畏水, 象天法地), "Fusion of the imitation of nature and the subjective ideas of the artist" (外师造化, 中得心源), and "Free and unfettered, enjoy the joy of leisure" (逍遥自得, 享闲居之乐) as the water aesthetic thoughts of the garden. In addition, this article provides some reference for the current landscape design. (shrink)

A self-perceived lack of training in ethical theories and related pedagogy has kept many engineering faculty members from teaching data ethics, an important aspect of engineering research that has become more salient in recent years. This paper describes the development of a module, which includes concepts, cases, policies, and best practices, to support the teaching of ethical data practice. Based on a user-oriented design approach and a moral literacy framework, the module was designed to be used in different courses and (...) co-curricular activities for students of varying levels of competence to improve their ability to identify and analyze ethical problems associated with the handling of research data. This work seeks to encourage ethical reflection on researchers’ data practice through the idea of an “ecology of data,” which highlights the co-production of data by multiple, interconnected, and heterogeneous actors. This paper also presents online and in-class evidence about the impact and limitations of the module, which is now available for interested researchers and instructors to browse and use. (shrink)

Words and meanings are important categories in the history of Chinese philosophy. The so-called disputes over words and meanings explored the relationship between language and thinking. Generally speaking, these disputes originated in pre-Qin philosophy, flourished during the Wei and Jin dynasties, and declined in the Ming and Qing dynasties, leaving valuable data for philosophical investigations in the history of Chinese philosophy.

Online financial service is an essential part of consumption services provided by companies in modern society. It is vital to figure out the underlying mechanisms that influence online financial service use of college students in China, which is seldom explored. Drawing on the theory of planned behavior, this study explores the effect of personality traits and its joint effect with attitude on online financial service use of college students. Moreover, we examined the interaction effects of key variables in TPB in (...) the context of online financial services. The results indicated that the materialism value of Chinese college students has no direct effect on their intention to use online financial services but exerts an indirect effect through their attitude toward online financial services. College students' attitudes and perceived behavioral control are associated with their subjective norms, and in turn, affect their use intention of online financial services. In addition, perceived risk and perceived usefulness of online financial services also affect use intention through attitude and perceived behavioral control. The discussion of key findings, implications, and conclusions are provided. (shrink)

In _Sino-Theology and the Philosophy of History_ Leopold Leeb presents the ideas of an influential Chinese intellectual, Liu Xiaofeng, whose approach to the question of a Christian theology for China is both controversial and inspiring.

Fourth-order autonomous nonlinear differential equations can exhibit chaotic properties. In this study, we propose a family of fourth-order chaotic systems with infinite equilibrium points whose equilibria form closed curves of different shapes. First, the phase diagrams and Lyapunov exponents of the system family are simulated. The results show that the system family has complex phase diagrams and dynamic behaviors. Simulation analysis of the Poincarè mapping and bifurcation diagrams shows that the system has chaotic characteristics. The circuit simulation model is constructed (...) and simulated in Multisim. The circuit simulation results coincide with the numerical simulation results, which verifies the circuit feasibility of the system. Then, based on Lyapunov stability theory and the adaptive control method, the synchronous control of the system with infinite equilibria is designed. Numerical simulation results verify that the system synchronization with the adaptive control method is well. Finally, the synchronous drive system is used for image encryption, the response system is used for decryption, and color image encryption is realized by combining deoxyribonucleic acid coding and operating rules. Therefore, this study not only enriched the research on infinite equilibria chaotic systems but also further expanded secure communication technology by combining chaotic synchronization control and DNA coding in image encryption. (shrink)

This exploration aims to study the emotion recognition of speech and graphic visualization of expressions of learners under the intelligent learning environment of the Internet. After comparing the performance of several neural network algorithms related to deep learning, an improved convolution neural network-Bi-directional Long Short-Term Memory algorithm is proposed, and a simulation experiment is conducted to verify the performance of this algorithm. The experimental results indicate that the Accuracy of CNN-BiLSTM algorithm reported here reaches 98.75%, which is at least 3.15% (...) higher than that of other algorithms. Besides, the Recall is at least 7.13% higher than that of other algorithms, and the recognition rate is not less than 90%. Evidently, the improved CNN-BiLSTM algorithm can achieve good recognition results, and provide significant experimental reference for research on learners’ emotion recognition and graphic visualization of expressions in an intelligent learning environment. (shrink)

本书系统深入研究中国共产党人运用、丰富和发展马克思主义哲学的理论成果和重要文献,阐述马克思主义哲学中国化的历史进程的发展规律,揭示中国化马克思主义哲学的理论体系和思想逻辑。.

本书对自组织理论进行综合性研究,并探讨了关于自然界自组织演化的自然图景和自然观,关于自然科学自组织演化的科学图景和科学观。.

We propose that local corruption distorts the allocation of government-controlled resources and impairs the contract environment, thereby reducing firms’ use or suppliers’ provision of trade credit. We use a sample of Chinese-listed firms from 2007 to 2020 to examine the role of local corruption in firms’ access to trade credit and find that the level of local corruption is negatively related to firms’ trade credit use. This effect is more pronounced in firms with weak (vs. strong) internal governance, slack (tight) (...) external monitoring and high (low) supplier concentration. The results of path analysis show that local corruption extends short-term bank loans as well as government subsidies and impairs firms’ accounting quality, thereby inhibiting firms’ demand for or suppliers’ provision of trade credit. Moreover, the post-2012 anti-corruption campaign in China plays a significant role in correcting the misallocation of trade credit caused by corruption. The results of this study illuminate the negative external effects of local corruption on trade credit. (shrink)

As one of the foundations of existential positive psychology, self-transcendence can bring positive intrapersonal and interpersonal outcomes, especially in the COVID-19 era in which people are suffering huge mental stress. Based on Schwartz's theory of human basic values, the current study combines variable-centered and person-centered approaches to examine the relationships between adolescents' values and mental health across two regions in China. The results generally showed that both self-enhancement and conservation values were positively correlated with depression and loneliness, while both self-transcendence (...) and openness to change values negatively correlated with depression and loneliness. The results also showed that there were four value clusters, and, compared to adolescents in the self-focus and undifferentiated values cluster, all adolescents in the anxiety-free values cluster reported lower depression and loneliness, while all adolescents in the other-focus values cluster reported higher depression and loneliness. The differences between the two regional groups only emerged in depression. Specifically, adolescents in Shanghai have higher levels of depression than adolescents in Qingdao. This study provides some evidence for the new science of self-transcendence among adolescents and also sheds light on how we may improve the level of mental health during the COVID-19 era. (shrink)

The dependency of a speech recognition system on the accent of a user leads to the variation in its performance, as the people from different backgrounds have different accents. Accent labeling and conversion have been reported as a prospective solution for the challenges faced in language learning and various other voice-based advents. In the English TTS system, the accent labeling of unregistered words is another very important link besides the phonetic conversion. Since the importance of the primary stress is much (...) greater than that of the secondary stress, and the primary stress is easier to call than the secondary stress, the labeling of the primary stress is separated from the secondary stress. In this work, the labeling of primary accents uses a labeling algorithm that combines morphological rules and machine learning; the labeling of secondary accents is done entirely through machine learning algorithms. After 10 rounds of cross-validation, the average tagging accuracy rate of primary stress was 94%, the average tagging accuracy rate of secondary stress was 94%, and the total tagging accuracy rate was 83.6%. This perceptual study separates the labeling of primary and secondary accents providing the promising outcomes. (shrink)

In this paper, the method of mutual information is used to study the economic dependence among the provinces in Chinaʼs Eastern Coastal Economic Belt from 2015 to 2020, and the core structure of the dependence is depicted. The results show that, first of all, there is a wide range of economic dependence among the provinces in the Eastern Coastal Economic Belt, and the dependence changes with the different states of economic development. Secondly, the phenomenon of geographical clustering is not obvious. (...) Most provinces maintain a strong economic dependence relationship with the economically developed provinces, and this dependence relationship is relatively stable, while the economically underdeveloped provinces are often on the edge of the dependence structure. Finally, the economically developed provinces maintain strong economic dependence with each other, such as Jiangsu, Shandong, and Zhejiang, and Beijing, Guangdong, and Shanghai. However, the former three provinces are more in the core position of this structure, that is, the other provinces maintain the stronger dependence relationship with these three provinces. (shrink)

In this paper, we investigate the ultimate bound set and positively invariant set of a 3D Lorenz-like chaotic system, which is different from the well-known Lorenz system, Rössler system, Chen system, Lü system, and even Lorenz system family. Furthermore, we investigate the global exponential attractive set of this system via the Lyapunov function method. The rate of the trajectories going from the exterior of the globally exponential attractive set to the interior of the globally exponential attractive set is also obtained (...) for all the positive parameters values a,b,c. The innovation of this paper is that our approach to construct the ultimate bounded and globally exponential attractivity sets assumes that the corresponding sets depend on some artificial parameters ; that is, for the fixed parameters of the system, we have a series of sets depending on λ and m. The results contain the known result as a special case for the fixed λ and m. The efficiency of the scheme is shown numerically. The theoretical results may find wide applications in chaos control and chaos synchronization. (shrink)

To help retailers gain consumers’ trust, many studies have investigated antecedents of consumer trust. However, distrust, a concept closely related to trust, has attracted only sporadic research attention. As a result, whether factors that increase consumer trust can eliminate consumer distrust is unclear. To deepen understanding of trust and distrust, this study applies the critical incident technique to identify and compare the antecedents of trust and distrust of Chinese consumers. The results show that the antecedents of distrust differ from those (...) of trust, indicating different formulation mechanisms of both. Therefore, on the one hand, retailers should pay attention to increasing consumer trust, and on the other hand, they should develop marketing activities to reduce consumer distrust. (shrink)