Authors De Marco and colleagues have presented a new model on the concept of invasiveness, redefining both its technical definition and practical implementation.1 While the authors raise valid critiques regarding the discrepancy in definitions, I cannot help but wonder about the purpose of redefining terms for which little confusion, if any, exists? This commentary seeks to scrutinise the rationale supporting the new model in the absence of significant clinical confusion and to explore the implications for clinical practice. Initially, one may (...) notice there is no mention of clinical relevancy, confusion among patients or whether the discrepancy in terms is causing miscommunication. It seems reasonable that some clinical confusion may exist, but so too does a similar imbalance of terms when speaking technically across the specialties; take depression and its definition as a primary example. While I certainly agree with the illustration of non-invasive prenatal testing being compared with venous blood draws as a disparity in terminology, little evidence suggests confusion concerning the nosology.2 The medical community, including both physicians and patients, recognises that the terminology is specifically used within the …. (shrink)

The integrated information theory (IIT) is an ambitious theory of consciousness that aims to provide both a neuroscientific and a metaphysical account of consciousness by identifying consciousness with integrated information. In the philosophical literature, IIT is often associated with a panpsychist worldview. In this paper, I show that IIT can be considered, instead, as a form of emergentism that is incompatible with panpsychism. First, I show that the panpsychist interpretation of IIT is based on two properties of integrated information: intrinsicality (...) and fundamentality. I show that the way IIT deals with these two properties, however, aligns better with emergentism than panpsychism. Then, after plugging some anti-panpsychist assumptions into IIT’s structure, I analyse different philosophical options for interpreting the formal result of causal emergence of integrated information in terms of dependence on and autonomy from its physical substrate. The upshot is that integrated information can be seen as dependent upon the fusion of the cause-effect powers of a physical substrate, and as autonomous in virtue of global-to-local determination. According to this interpretation, consciousness is the constraining power of the system as a whole upon itself, when this power emerges from the fusion on the cause-effect powers of the system’s components. (shrink)

Prized Attic honey is an often-neglected topic in studies of Athenian productions, despite the considerable spread of production, as attested by archaeological finds of terracotta beehives throughout the territory. Literary sources also frequently mention honey produced in Attica, especially the most famous and prized variety from Mount Hymettus. In this paper, after a mention of the peculiarity of the traditions about honey in the classical world, the importance and fame of the Attic product is emphasised. The sources that praise the (...) product are here classified in three groups, namely the authors who focus on its sweetness and fragrance, the ones who describe Attic honey generically in relation to its prestige and the sources which compares it to honey from other regions. Afterwards, my further goal is to assess the possible connection between honey and the funerary sphere in Attica. This relation is explored also through the reanalysis of some interpretations proposed for a fictile group of geometric Attic models. (shrink)

The American Journal of Bioethics, Volume 11, Issue 6, Page 60-62, June 2011.

This paper examines Derrida's critique of Husserl's notion of pure presence. Husserl's theory of temporality in _The Phenomenology of Internal Time Consciousness supports a philosophy of pure presence, but Husserl's notion of presence is not, as Derrida would have it, one which "reject(s) the 'after-event' of the becoming conscious of an 'unconscious content' which is the structure of temporality implied through-out Freud's texts". Husserl's notion of presence is, rather, transcendental, hyletic and unconscious. Dissemination, characterized by a lack of stable meaning, (...) nonorigin, and departure from the rules of logic, is constituted by the relation of transcendental presence to the mundane. (shrink)

Hepatocellular carcinoma represents the third leading cause of cancer-related death. Because HCC is multicentric with time, excluding the few transplanted patients, sooner or later it becomes untreatable with loco-regional therapies and, until some years ago, it was not responsive to systemic therapies. In 2005 a randomized trial indicated the efficacy of a product containing stem cell differentiation stage factors taken from zebrafish embryos during the stage in which the totipotent stem cells are differentiating into the pluripotent adult stem cells. In (...) such a trial the patients, with “intermediate” and “advanced” HCC according to Barcelona Clinic Liver Cancer/American Association for the Study of Liver Diseases guidelines, presented benefit in terms of performance status and objective tumoral response, with some cases of complete response, that is, sustained disappearance of the neoplastic areas or blood supply therein, accompanied by normalization of alpha-fetoprotein... (shrink)

Acknowledgments I wish to express my gratitude to Dr. Jakob Amstutz for his continual feedback during my writing of this work. ...

The purpose of this essay is to show that the version of epistemological infinitism defended by Peter Klein is externalistic in character. I present the most important questions infinitism is supposed to resolve and also present the fundamental difference regarding internalism and externalism in epistemology. I conclude with an indication of what would be the best way to understand infinitism and how to evade the problems that emerge from Klein’s externalist infinitism.

The chapter 'Of power' of Locke's Essay Concerning Human Understanding is a very fine discussion of agency and a very complex piece of philosophy. It is the result of the superimposition of at least three layers of text (those of the first, second and fifth editions of the Essay), expressive of widely differing views of the same matters. The argument concerning agency and free will that it puts forward (as it now stands, reporting Locke's last word on the subject) is (...) thus beset with problems, and even inconsistencies. But these textual and analytical difficulties should not hide from us the relevance and, in a way, the deep coherence of Locke's philosophy of action. In what follows, I will attempt to cast some light on this complicated interpretive and conceptual matter, by a careful reading of some parts of Locke's discussion. The first section shows how accounting for the evaluation and choice of remote goods, in terms of their real value and in preference to smaller, nearer ones, is a crucial problem for Locke's philosophy of action. The second section reads Locke's move from an internalist to an externalist view of motivation as a first, conceptually complex step towards such an account; and shows how this is linked to a change in the concept of will. The third and fourth sections reconstruct Locke's account (a pattern of suspension and examination of occurrent desire); discuss the role of the motivational and normative concept of happiness; and cast some doubt on the consistency of Locke's position. (shrink)

A central issue of cognitive neuroscience is to understand how a large collection of coupled neurons combines external signals with internal memories into new coherent patterns of meaning. An external stimulus localized at some input spreads over a large assembly of coupled neurons, building up a collective state univocally corresponding to the stimulus. Thus, the synchronization of spike trains of many individual neurons is the basis of a coherent perception. Based on recent investigations of homoclinic chaotic systems and their synchronization, (...) a novel conjecture for the dynamics of single neurons and, consequently, for neuron assemblies is formulated. Homoclinic chaos is proposed as a suitable way to code information in time by trains of equal spikes occurring at apparently erratic times. In order to classify the set of different perceptions, the percept space can be given a metric structure by introducing a distance measure between distinct percepts. The distance in percept space is conjugate to the duration of the perception in the sense that an uncertainty relation in percept space is associated with time-limited perceptions. This coding of different percepts by synchronized spike trains entails fundamental quantum features which are not restricted to microscopic phenomena. It is conjectured that they are related to the details of the perceptual chain rather than depending on Planck's action. (shrink)

O problema do conhecimento fácil tem sido definido na literatura epistemológica contemporânea com um problema que nasce de duas formas distintas. O propósito deste ensaio é mostrar que essas supostas maneiras diferentes de gerar o mesmo problema em verdade originam dois problemas distintos, que requerem respostas distintas. Um deles está relacionado à aquisição fácil (inaceitável) de conhecimento de primeira-ordem e o outro à aquisição fácil (inaceitável) de conhecimento de segunda-ordem. Além disso, é apresentada a maneira como o infinitismo, a teoria (...) epistêmica segundo a qual as razões que justificam uma opinião devem ser infinitas em número e não-repetidas, pode lidar com cada um desses problemas. (shrink)

ABSTRACT This essay presents the chief reasons for making a distinction between propositional and doxastic justification and, also, points out two things: no theory of propositional justification implies a theory of doxastic justification; infinitism is, essentially, a theory of propositional justification. Additionally, this paper tries to shed some light on the three conjointly sufficient conditions for a proper infinitist view of propositional justification.

O problema do critério é um dos mais importantes da epistemologia. A resposta que se dá a ele definirá um aspecto fundamental das teorias do conhecimento. Neste ensaio, o problema do critério é apresentado e algumas das conseqüências geradas pela aceitação de exigências metaepistemicas são analisadas. Em especial, essas conseqüências são avaliadas em relação ao infinitismo – a teoria epistemológica segundo a qual as razões que sustentam nossas crenças devem ser infinitas em número e não-repetidas. Ao final, sustenta-se que cláusulas (...) que exigem que a metajustificação seja necessária para o conhecimento não apenas tornam as teorias epistemológicas mais plausíveis, mas também que a ausência de tais exigências acaba criando problemas muito difíceis, como o assim chamado “problema do conhecimento fácil”. PALAVRAS-CHAVE – Infinitismo. Problema do critério. Metajustificação. Conhecimento. Metaconhecimento. Ceticismo. ABSTRACT This essay discusses the Problem of the Criterion, one of the most important problems in Epistemology. The answer given to this problem will shape a fundamental aspect of theories of knowledge. It also analyzes some of the consequences epistemological theories may face in accepting metaepistemological requirements. These consequences are given special consideration with regard to Infinitism, the epistemological theory according to which the reasons that support our beliefs must be infinite and non-repeating. Finally, this essay claims not only that those propositions that require metajustification make any theory, even Infinitism, more plausible, but also that the absence of such requirements creates difficult problems, such as the so-called “Problem of Easy Knowledge.” KEY WORDS – Infinitism. Problem of the Criterion. Metajustification. Knowledge. Metaknowledge. Skepticism. (shrink)

Entification is now displayed in its nude and native state, and serves to explain the constant mental process, and the true nature of the representations of ...

This chapter contains section titled: Direct Passions Pleasure and Desire Reason and Passion References Further Reading.

On the one hand, much has been written on Theodosius Dobzhansky’s central role in the development of the field of population genetics and modern evolutionary theory, as well as on his sociopolitical worldview in the middle of the Twentieth Century. On the other hand, much has also been written on Dobzhansky’s role in the institutionalization of genetics in Brazil, where he spent a considerable amount of time. Unfortunately, these literatures developed without any points of intersection or cross-reference. This article places (...) Dobzhansky’s work in Brazil in the broader contexts of the science and politics of its historical period. (shrink)

Food prices are a daily concern in many households’ decision-making, especially when people want to have healthier diets. Employing Bayesian Mindsponge Framework (BMF) analytics on a dataset of 710 Indonesian citizens, we found that people from wealthier households are less likely to have concerns about food prices. However, the degree of health considerations in food consumption was found to moderate against the above association. In other words, people of higher income-based social classes may worry more about food prices if they (...) care more about the health impacts of their food choices. These findings provide more insights for policymakers on the psychological aspects of promoting the balance between finance and health in food consumption. (shrink)

Consciousness vehicle externalism is the claim that the material machinery of a subject’s phenomenology partially leaks outside a subject’s brain, encompassing bodily and environmental structures. The DEUTS argument is the most prominent argument for CVE in the sensorimotor enactivists’ arsenal. In a recent series of publications, Kirchhoff and Kiverstein have deployed such an argument to claim that a prominent view of neural processing, namely predictive processing, is fully compatible with CVE. Indeed, in Kirchhoff and Kiverstein’s view, a proper understanding of (...) predictive processing mandates CVE. In this essay, we critically examine Kirchhoff and Kiverstein’s argument. Our aim is to argue in favor of the following three points. First, that Kirchhoff and Kiverstein’s emphasis on cultural practices lends no support to CVE: at best, it vindicates some form of content externalism about phenomenal content. Secondly, the criteria Kirchhoff and Kiverstein propose to identify a subject’s phenomenal machinery greatly overgeneralize, leaving them open to a “consciousness bloat” objection, which is an analog of the cognitive bloat objection against the extended mind. Lastly, we will argue that the “consciousness bloat” problem is inbuilt in the very argumentative structure of the DEUTS argument. We will thus conclude that, contrary to the philosophical mainstream, DEUTS is not the best argument for CVE in the sensorimotor enactivists’ argumentative arsenal. (shrink)