When people understand a counterfactual such as “if the flowers had been roses, the trees would have been orange trees,” they think about the conjecture, “there were roses and orange trees,” and they also think about its opposite, the presupposed facts. We test whether people think about the opposite by representing alternates, for example, “poppies and apple trees,” or whether models can contain symbols, for example, “no roses and no orange trees.” We report the discovery of an inference‐to‐alternates effect—a tendency (...) to make an affirmative inference that refers to an alternate even from a negative minor premise, for example, “there were no orange trees, therefore there were poppies.” Nine experiments show the inference‐to‐alternates effect occurs in a binary context, but not a multiple context, and for direct and indirect reference; it can be induced and reduced by prior experience with similar inferences, and it also occurs for indicative conditionals. The results have implications for theories of counterfactual conditionals, and of negation. (shrink)

We examine two competing effects of beliefs on conditional inferences. The suppression effect occurs for conditionals, for example, “if she watered the plants they bloomed,” when beliefs about additional background conditions, for example, “if the sun shone they bloomed” decrease the frequency of inferences such as modus tollens (from “the plants did not bloom” to “therefore she did not water them”). In contrast, the counterfactual elevation effect occurs for counterfactual conditionals, for example, “if she had watered the plants they would (...) have bloomed,” when beliefs about the known or presupposed facts, “she did not water the plants and they did not bloom” increase the frequency of inferences such as modus tollens. We report six experiments that show that beliefs about additional conditions take precedence over beliefs about presupposed facts for counterfactuals. The modus tollens inference is suppressed for counterfactuals that contain additional conditions (Experiments 1a and 1b). The denial of the antecedent inference (from “she did not water the plants” to “therefore they did not bloom”) is suppressed for counterfactuals that contain alternatives (Experiments 2a and 2b). We report a new “switched‐suppression” effect for conditionals with negated components, for example, “if she had not watered the plants they would not have bloomed”: modus tollens is suppressed by alternatives and denial of the antecedent by additional conditions, rather than vice versa (Experiments 3a and 3b). We discuss the implications of the results for alternative theories of conditional reasoning. (shrink)

This paper defends an inferential conception of scientific representation. It approaches the notion of representation in a deflationary spirit, and minimally characterizes the concept as it appears in science by means of two necessary conditions: its essential directionality and its capacity to allow surrogate reasoning and inference. The conception is defended by showing that it successfully meets the objections that make its competitors, such as isomorphism and similarity, untenable. In addition the inferential conception captures the objectivity of the cognitive representations (...) used by science, it sheds light on their truth and completeness, and it explains the source of the analogy between scientific and artistic modes of representation. (shrink)

I argue against theories that attempt to reduce scientific representation to similarity or isomorphism. These reductive theories aim to radically naturalize the notion of representation, since they treat scientist's purposes and intentions as non-essential to representation. I distinguish between the means and the constituents of representation, and I argue that similarity and isomorphism are common but not universal means of representation. I then present four other arguments to show that similarity and isomorphism are not the constituents of scientific representation. I (...) finish by looking at the prospects for weakened versions of these theories, and I argue that only those that abandon the aim to radically naturalize scientific representation are likely to be successful. (shrink)

It is shown that the before-before (or Suarez-Scarani) experiment refutes hidden variable models with a deterministic (“realistic”) nonlocal part, whereas experiments violating Leggett-type inequalities refute models with biased random local part. Therefore the claim that Gröblacher et al. (Nature 446:871–875, 2007) present “an experimental test of nonlocal realism” is misleading, and Marek Żukowski’s (Found. Phys. 38:1070, 2008) comment misses the point. A new experiment is suggested.

Si la virtus de la Antigüedad era la fuerza, la valentía y el coraje, y en la modernidad la diligencia, el trabajo, el mérito y el esfuerzo, actualmente se ha instalado la commoditas, una suerte de pseudovirtud nihilista que reivindica la ociosidad, el igualitarismo radical y el entretenimiento. La sociedad contemporánea posmoderna ha superado tanto la metafísica filosófica grecorromana como la teología cristiana, tanto el racionalismo y el empirismo ilustrado como el idealismo romántico decadentista y el positivismo materialista, y ha (...) entrado en una suerte de fin de la historia de nihilismo lúdico autocomplaciente y autosatisfecho. Concluimos que la commoditas está para quedarse y reconfigurará la naturaleza del ser humano en función de una nueva mentalidad que empalidece a la tradición hasta prácticamente anularla. (shrink)

We report five experiments showing that the activation of the end-terms of a syllogism is determined by their position in the composite model of the premises. We show that it is not determined by the position of the terms in the rule being applied (Ford, 1994), by the syntactic role of the terms in the premises (Polk & Newell, 1995; Wetherick & Gilhooly, 1990), by the type of conclusion (Chater & Oaksford, 1999), or by the terms from the source premise (...) (Stenning & Yule, 1997). In our first experiment we found that after reading a categorical premise, the most active term is the last term in the premise. In Experiments 2, 3, and 4 we demonstrated that this pattern of activity is due to the position of the concepts in the model of the premises, regardless of the delay after reading the premises (150 or 2000 msec) or the quantity of the quantifiers (universal or existential). The fifth experiment showed that the pattern switches around after participants evaluate a conclusion. We propose that the last element in the model maintains a higher level of activity during the comprehension process because it is generally used to attach the incoming information. After this process, the first term becomes more active because it is the concept to which the whole representation is referred. These results are predicted by the mental model theory (Johnson-Laird & Byrne, 1991), but not by the verbal reasoning theory (Polk & Newell, 1995), the graphical methods theory (Yule & Stenning, 1992), the attachment-heuristic theory (Chater & Oaksford, 1999), or the mental rules theory (Ford, 1994). (shrink)

L'index detaille de la Metaphysique d'Aristote publie en 1597 par Suarez, constitue une introduction aux Disputes metaphysiques. Il a pour objectif de produire les conditions d'un renouvellement de l'heritage de la Metaphysique d'Aristote en redefinissant le contenu et les limites d'une science de l'etant.Le projet de refondation de la metaphysique comme ontologie s'effectue dans cet ouvrage de presentation en quatre moments:1) L'exposition du probleme de la nature de la connaissance qui implique le depassement de l'equivocite de la notion de sagesse.2) (...) La determination de l'objet, des proprietes et des principes veritables de la metaphysique en tant que science de l'universel, c'est a dire de l'etantite de l'etant selon son abstraction la plus extreme.3) La redefinition du statut de la realite a partir d'une theorie de la representation de l'objet qui fasse abstraction de l'objet, c'est a dire qui procede a l'indifferenciation des etants afin d'en donner une representation universelle et abstraite; ainsi est affirme le primat d'une ontologie de l'essence sur toute ontotheologie.4) Enfin, la mise en place d'un systeme de reference transcendantal rendant possible une fondation universelle de la comprehension de l'etant par la mediation d'une theorie du concept.L'index prefigure ainsi, par son ambition et sa demarche, ce que Heidegger nommera, en evoquant la philosophie de Suarez, l'avenement du "caractere fondamental de la metaphysique moderne". (shrink)

Bourrat and Griffiths :33, 2018) have recently argued that most of the evidence presented by holobiont defenders to support the thesis that holobionts are evolutionary individuals is not to the point and is not even adequate to discriminate multispecies evolutionary individuals from other multispecies assemblages that would not be considered evolutionary individuals by most holobiont defenders. They further argue that an adequate criterion to distinguish the two categories is fitness alignment, presenting the notion of fitness boundedness as a criterion that (...) allows divorcing true multispecies evolutionary individuals from other multispecies assemblages and provides an adequate criterion to single out genuine evolutionary multispecies assemblages. A consequence of their criterion is that holobionts, as conventionally defined by hologenome defenders, are not evolutionary individuals except in very rare cases, and for very specific host-symbiont associations. This paper is a critical response to Bourrat and Griffiths’ arguments and a defence of the arguments presented by holobiont defenders. Drawing upon the case of the hologenomic basis of the evolution of sanguivory in vampire bats, I argue that Bourrat and Griffiths overlook some aspects of the biological nature of the microbiome that justifies the thesis that holobionts are evolutionarily different to other multispecies assemblages. I argue that the hologenome theory of evolution should not define the hologenome as a collection of genomes, but as the sum of the host genome plus some traits of the microbiome which together constitute an evolutionary individual, a conception I refer to as the stability of traits conception of the hologenome. Based on that conception I argue that the evidence presented by holobiont defenders is to the point, and supports the thesis that holobionts are evolutionary individuals. In this sense, the paper offers an account of the holobiont that aims to foster a dialogue between hologenome advocates and hologenome critics. (shrink)

This paper expands on, and provides a qualified defence of, Arthur Fine's selective interactions solution to the measurement problem. Fine's approach must be understood against the background of the insolubility proof of the quantum measurement. I first defend the proof as an appropriate formal representation of the quantum measurement problem. The nature of selective interactions, and more generally selections, is then clarified, and three arguments in their favour are offered. First, selections provide the only known solution to the measurement problem (...) that does not relinquish any of the explicit premises of the insolubility proofs. Second, unlike some no-collapse interpretations of quantum mechanics, selections suffer no difficulties with non-ideal measurements. Third, unlike most collapse interpretations, selections can be independently motivated by an appeal to quantum propensities. IntroductionThe problem of quantum measurement2.1 The ignorance interpretation of mixtures2.2 The eigenstate–eigenvalue link2.3 The quantum theory of measurementThe insolubility proof of the quantum measurement3.1 Some notation3.2 The transfer of probability condition (TPC)3.3 The occurrence of outcomes condition (OOC)A defence of the insolubility proof4.1 Stein's critique4.2 Ignorance is not required4.3 The problem of quantum measurement is an idealisationSelections5.1 Representing dispositional properties5.2 Selections solve the measurement problem5.3 Selections and ignoranceNon-ideal selections6.1 No-collapse interpretations and non-ideal measurements6.2 Exact and approximate measurements6.3 Selections for non-ideal interactions6.4 Approximate selections6.5 Implications for ignoranceSelective interactions test quantum propensities7.1 Equivalence classes as physical ‘aspects’: a critique7.2 Quantum dispositions7.3 Selections as a propensity modal interpretation7.4 A comparison with Popper's propensity interpretation. (shrink)

Contemporary biological research has suggested that some host–microbiome multispecies systems (referred to as “holobionts”) can in certain circumstances evolve as unique biological individual, thus being a unit of selection in evolution. If this is so, then it is arguably the case that some biological adaptations have evolved at the level of the multispecies system, what we call hologenomic adaptations. However, no research has yet been devoted to investigating their nature, or how these adaptations can be distinguished from adaptations at the (...) species-level (genomic adaptations). In this paper, we cover this gap by investigating the nature of hologenomic adaptations. By drawing on the case of the evolution of sanguivory diet in vampire bats, we argue that a trait constitutes a hologenomic adaptation when its evolution can only be explained if the holobiont is considered the biological individual that manifests this adaptation, while the bacterial taxa that bear the trait are only opportunistic beneficiaries of it. We then use the philosophical notions of emergence and inter-identity to explain the nature of this form of individuality and argue why it is special of holobionts. Overall, our paper illustrates how the use of philosophical concepts can illuminate scientific discussions, in the trend of what has recently been called metaphysics of biology. (shrink)

There has been an intense discussion, albeit largely an implicit one, concerning the inference of causal hypotheses from statistical correlations in quantum mechanics ever since John Bell’s first statement of his notorious theorem in 1966. As is well known, its focus has mainly been the so-called Einstein-Podolsky-Rosen (“EPR”) thought experiment, and the ensuing observed correlations in real EPR like experiments. But although implicitly the discussion goes as far back as Bell’s work, it is only in the last two decades that (...) it has become recognizably and explicitly a debate about causal inference in the quantum realm. The bulk of this paper is devoted to a review of three influential arguments in the philosophical literature that aim to show that causal models for the EPR correlations are impossible, due to Bas Van Fraassen, Daniel Hausman and Huw Price. I contend that all these arguments are inconclusive since they contain premises or presuppositions that are false, unwarranted, or at least controversial. Five different common cause models are outlined that seem perfectly viable for the EPR correlations. These models are then employed to illustrate various difficulties with the premises and presuppositions underlying Van Fraassen’s, Hausman’s and Price’s arguments. In all these cases it is argued that the difficulties cut deep against these authors’ own theories of causation and causal inference. My conclusions are that causal models for the EPR correlations remain viable, that philosophical work is still required to assess their relative virtues, and that in any case the mere theoretical conceivability and empirical possibility of these models sheds doubts over Van Fraassen’s, Hausman’s and (important elements in) Price’s theories of causation and causal inference. (shrink)

Symbiosis plays a fundamental role in contemporary biology, as well as in recent thinking in philosophy of biology. The discovery of the importance and universality of symbiotic associations has brought new light to old debates in the field, including issues about the concept of biological individuality. An important aspect of these debates has been the formulation of the hologenome concept of evolution, the notion that holobionts are units of natural selection in evolution. This review examines the philosophical assumptions that underlie (...) recent proposal of the hologenome concept of evolution, and traces those debates back in time to their historical origins, to the moment when the connection between the topics of symbiosis and biological individuality first caught the attention of biologists. The review is divided in two parts. The first part explores the historical origins of the connection between the notion of symbiosis and the concept of biological individuality, and emphasizes the role of A. de Bary, R. Pound, A. Schneider and C. Merezhkowsky in framing the debate. The second part examines the hologenome concept of evolution and explores four parallelisms between contemporary debates and the debates presented in the first part of the essay, arguing that the different debates raised by the hologenome concept were already present in the literature. I suggest that the novelty of the hologenome concept of evolution lies in the wider appreciation of the importance of symbiosis for maintaining life on Earth as we know it. Finally, I conclude by suggesting the importance of exploring the connections among contemporary biology, philosophy of biology and history of biology in order to gain a better understanding of contemporary biology. (shrink)

Holobionts are symbiotic assemblages composed by a host plus its microbiome. The status of holobionts as individuals has recently been a subject of continuous controversy, which has given rise to two main positions: on the one hand, holobiont advocates argue that holobionts are biological individuals; on the other, holobiont detractors argue that they are just mere chimeras or ecological communities, but not individuals. Both parties in the dispute develop their arguments from the framework of the philosophy of biology, in terms (...) of what it takes for a “conglomerate” to be considered an interesting individual from a biological point of view. However, the debates about holobiont individuality have important ontological implications that have remained vaguely explored from a metaphysical framework. The purpose of this paper is to cover that gap by presenting a metaphysical approach to holobionts individuality. Drawing upon a conception of natural selection that puts the focus on the transgenerational recurrence of the traits and that supports the thesis that holobionts are units of selection, we argue that holobionts bear emergent traits and exert downward powers over the entities that compose them. In this vein, we argue, a reasonable argument can be made for conceiving holobionts as emergent biological individuals. (shrink)

A Richard Rorty se le considera hoy en día como uno de los filósofos más importantes de Norteamérica. Es posible que esta afirmación sea discutible; lo indiscutible es que, a juicio de los críticos, es el mejor escritor filosófico después de Bertrand Russell….

Philippe Huneman has recently questioned the widespread application of mechanistic models of scientific explanation based on the existence of structural explanations, i.e. explanations that account for the phenomenon to be explained in virtue of the mathematical properties of the system where the phenomenon obtains, rather than in terms of the mechanisms that causally produce the phenomenon. Structural explanations are very diverse, including cases like explanations in terms of bowtie structures, in terms of the topological properties of the system, or in (...) terms of equilibrium. The role of mathematics in bowtie structured systems and in topologically constrained systems has recently been examined in different papers. However, the specific role that mathematical properties play in equilibrium explanations requires further examination, as different authors defend different interpretations, some of them closer to the new-mechanistic approach than to the structural model advocated by Huneman. In this paper, we cover this gap by investigating the explanatory role that mathematics play in Blaser and Kirschner’s nested equilibrium model of the stability of persistent long-term human-microbe associations. We argue that their model is explanatory because: i) it provides a mathematical structure in the form of a set of differential equations that together satisfy an ESS; ii) that the nested nature of the ESSs makes the explanation of host-microbe persistent associations robust to any perturbation; iii) that this is so because the properties of the ESS directly mirror the properties of the biological system in a non-causal way. The combination of these three theses make equilibrium explanations look more similar to structural explanations than to causal-mechanistic explanation. (shrink)

An English translation of the Second Disputation.

The hologenome concept of evolution is a hypothesis about the evolution of animals and plants. It asserts that the evolution of animals and plants was partially triggered by their interactions with their symbiotic microbiomes. In that vein, the hologenome concept posits that the holobiont (animal host + symbionts of the microbiome) is a unit of selection. -/- The hologenome concept has been severely criticized on the basis that selection on holobionts would only be possible if there were a tight transgenerational (...) host-genotype-to-symbiont-genotype connection. As our current evidence suggests that this is not the case for most of the symbiont species that compose the microbiome of animals and plants, the opportunity for holobiont selection is very low in relation to the opportunity for selection on each of the species that compose the host microbiome. Therefore, holobiont selection will always be disrupted ‘from below’, by selection on each of the species that compose the microbiome. -/- This thesis constitutes a conceptual effort to defend philosophically the hologenome concept. I argue that the criticism according to which holobiont selection requires tight transgenerational host-genotype-to-symbiont-genotype connection is grounded on a metaphysical view of the world according to which the biological hierarchy needs to be nested, such that each new level of selection includes every entity from below. Applied to hologenomes, it entails that the hologenome is a collection of genomes, and selection of hologenomes is assumed to entail cospeciation of the host with the species that constitute its microbiome. -/- Against that interpretation, I propose the ‘stability of traits’ account, according to which hologenome evolution is the result of the action of natural selection in a non-nested hierarchical world. In that vein, hologenome evolution does not entail cospeciation, and thus it does not require tight transgenerational host-genotype-to-symbiont-genotype connection. By embracing a multilevel selection perspective, I argue that hologenome evolution results from the simultaneous action of natural selection on each of the lineages that compose the microbiome, and on the assemblage composed by the host genome plus the functional traits of its microbiome. Hologenome selection occurs when the evolution of the traits of the microbiome result from their effects on the fitness of the host, and it can take the form of multilevel selection 1, or multilevel selection 2. In both cases, hologenome selection entails the evolution of microbiome traits, as well as evolution of the host genome, rather than cospeciation of lineages. (shrink)

1Department of Philosophy, University of Bristol, 9 Woodland Road, Bristol BS8 1TB, UKScience Without Laws Ronald Giere Chicago, IL University of Chicago Press 1999 x + 285 Hardback£17.50.

Merleau-Ponty suggests that to perceive is to be “geared into” the world. In perceiving, we are related to a temporally structured modal space of bodily possibilities that is co-constituted by the body and the world. When we perceive, we are “geared into” this structure and responsive to it; when we misperceive, we are not. In misperceiving, we are unaware of our failure to be geared into the world, and in this respect, we lack awareness of what we are doing. In (...) explaining misperception via this lack of self-awareness, Merleau-Ponty anticipates a key feature of M. G. F. Martin's epistemic disjunctivism: the idea that perceptions and misperceptions can be indiscriminable because of a self-awareness we lack, rather than a set of positive phenomenal features that two experiences share. However, because Merleau-Ponty's account of self-awareness imposes relatively few cognitive demands, he is able to explain how adults, infants, and dogs can be self-aware in the same sense, and how they can fail to discriminate between their experiences in the same way. This provides Merleau-Ponty with the resources to answer Susanna Siegel's objection to epistemic disjunctivism on the basis of “cognitively unsophisticated hallucinators.”. (shrink)

In “The Toolbox of Science” (1995) together with Towfic Shomar we advocated a form of instrumentalism about scientific theories. We separately developed this view further in a number of subsequent works. Steven French, James Ladyman, Otavio Bueno and Newton Da Costa (FLBD) have since written at least eight papers and a book criticising our work. Here we defend ourselves. First we explain what we mean in denying that models derive from theory – and why their failure to do so should (...) be lamented. Second we defend our use of the London model of superconductivity as an example. Third we point out both advantages and weaknesses of FLBD’s techniques in comparison to traditional Anglophone versions of the semantic conception. Fourth we show that FLBD’s version of the semantic conception has not been applied to our case study. We conclude by raising doubts about FLBD’s overall project. (shrink)

The Coronavirus Disease 2019 pandemic, now a global health crisis, has surprised health authorities around the world. Recent studies suggest that the measures taken to curb the spread of the COVID-19 outbreak have generated issues throughout the population. Thus, it is necessary to establish and identify the possible risk factors related to the psychosocial and psychophysiological strain during the COVID-19 outbreak. The present extensive literature review assesses the social, psychological, and physiological consequences of COVID-19, reviewing the impact of quarantine measures, (...) isolation, vast human loss, social and financial consequences in the family’s economies, and its impact on the psychological health of the population. We also discussed the effect of psychophysiological factors, considering the impact of physical inactivity and modifications in nutritional habits, at psychological and physiological levels. The present review includes an actualized to date bibliography, articles for which were methodologically analyzed to verify they met the standards of quality and scientific accuracy. Authors understand the pandemic as a multifactorial event for which only a profound and extensive analysis would lead to better compression and efficient intervention in the near future. (shrink)

Kant and Heidegger argue that our subjectivity escapes scientific explanation, while also providing the conditions that enable it. This understanding of the relationship between subjectivity and science places limits on the explanatory scope of the sciences. But what makes transcendental reflection on the structure of subjectivity possible in the first place? Fink argues that transcendental philosophy encounters its own limits in attempting to characterize its own conditions of possibility. I argue that the limits of science and transcendental philosophy entail that (...) nature cannot be conceived as a specific object, or as a totality of objects in the world, but only as the ontological ground of phenomenal manifestation in general. Nature is not identical with anything discoverable in either science or phenomenology; it is, rather, the origin from which discovery of phenomena proceeds. (shrink)

It is still a matter of controversy whether the Principle of the Common Cause can be used as a basis for sound causal inference. It is thus to be expected that its application to quantum mechanics should be a correspondingly controversial issue. Indeed the early 90’s saw a flurry of papers addressing just this issue in connection with the EPR correlations. Yet, that debate does not seem to have caught up with the most recent literature on causal inference generally, which (...) has moved on to consider the virtues of a generalised PCC inspired condition, the so called Causal Markov Condition. In this paper we argue that the CMC is an appropriate benchmark for debating possible causal explanations of the EPR correlations. But we go on to take issue with some pronouncements on EPR by defenders of the CMC. (shrink)

This paper critically reviews Philip Kitcher's most recent epistemology of science, real realism. I argue that this view is unstable under different understandings of the term 'representation', and that the arguments offered for the position are either unsound or invalid depending on the understanding employed. Suitably modified those arguments are however convincing in favor of a deflationary version of real realism, which I refer to as the bare view. The bare view accepts Kitcher's Galilean strategy, and the ensuing commitment to (...) the existence of unobservables; but it does not trade on a correspondence or copy theory of representation. So the bare view, unlike real realism, does not entail that our representations match reality even approximately. (shrink)

This paper aims to offer a new argument in defence bacterial species pluralism. To do so, I shall first present the particular issues derived from the conflict between the non-theoretical understanding of species as units of classification and the theoretical comprehension of them as units of evolution. Secondly, I shall justify the necessity of the concept of species for the bacterial world, and show how medicine and endosymbiotic evolutionary theory make use of different concepts of bacterial species due to their (...) distinctive purposes. Finally, I shall show how my argument provides a new source of defence for bacterial pluralism. (shrink)

This paper argues for a representational semantic conception of scientific theories, which respects the bare claim of any semantic view, namely that theories can be characterised as sets of models. RSC must be sharply distinguished from structural versions that assume a further identity of ‘models’ and ‘structures’, which we reject. The practice-turn in the recent philosophical literature suggests instead that modelling must be understood in a deflationary spirit, in terms of the diverse representational practices in the sciences. These insights are (...) applied to some mathematical models, thus showing that the mathematical sciences are not in principle counterexamples to RSC. (shrink)

This paper argues that if propensities are displayed in objective physical chances then the appropriate representation of these chances is as indexed probability functions. Two alternative formal models, or accounts, for the relation between propensity properties and their chancy or probabilistic manifestations, in terms of conditionals and conditional probability are first reviewed. It is argued that both confront important objections, which are overcome by the account in terms of indexed probabilities. A number of further advantages of the indexed probability account (...) are discussed, which suggest that it is promising as a general theory of objective physical chance. The paper ends with a discussion of the indexical character of the objective chances that are grounded in propensities. (shrink)

Scientific representation is a currently booming topic, both in analytical philosophy and in history and philosophy of science. The analytical inquiry attempts to come to terms with the relation between theory and world; while historians and philosophers of science aim to develop an account of the practice of model building in the sciences. This article provides a review of recent work within both traditions, and ultimately argues for a practice-based account of the means employed by scientists to effectively achieve representation (...) in the modelling sciences. (shrink)

The units or levels of selection debate concerns the question of what kind of biological systems are stable enough that part of their evolution is a result of the process of natural selection acting at their level. Traditionally, the debate has concerned at least two different, though related, questions: the question of the level at which interaction with the environment occurs, and the question of the level at which reproduction occurs. In recent years, biologists and philosophers have discussed a new (...) aspect of this debate, namely the possibility that certain multi-species consortia formed by a host and its microbiome may act as a unit of selection. This thesis, however, has not been without criticism, as it is doubtful that such consortia could meet the conditions required to achieve the degree of stability that would allow them to experience natural selection. The purpose of this paper is to systematically examine such criticisms and to defend the thesis that the holobiont/hologenome can act as a genuine level of selection both in the form of an interactor and in the form of a reproducer. To do so, it will be argued that the microbiome should be characterized in functional rather than taxonomic terms. (shrink)