In this article, we outline a simple and intuitively appealing procedure to derive default priors. The main idea is to regard the choice of such a prior as a formal Bayesian decision problem. We also discuss Jeffreys prior and more generally the reference prior of Bernardo (J R Stat Soc B 41:113–147, 1979) from this standpoint.

Infectious disease outbreaks in residential care are complex to manage and difficult to control. Research in this setting that includes individuals who lack capacity must conform to national legislation. We report here on our study that is investigating outbreaks of scabies, an itchy skin infection, in the residential care setting in the southeast of England. There appears to be a gap in legislative advice regarding the inclusion of people who lack capacity in research that takes place during time-limited acute scenarios (...) such as outbreaks. We received inconsistent advice from experts regarding, in particular, the role of nominated consultees. There is a potential inequality for vulnerable populations who cannot themselves provide informed consent in terms of their access to participation in a range of health-related research. (shrink)

For deliberations on the ethical and meta-ethical implications of Alfred North Whitehead's process philosophy, here are abstracts and papers from the Ethics Section of the 6th International Whitehead Conference held at the University of Salzburg in Salzburg, Austria in July 2006. In accordance with the conference schedule, there are three subsections. The subsection on "Metaphysics of Morals and Moral Theory" includes contributions from Franklin I. Gamwell (Does Morality Presuppose God?), John W. Lango (abstract only), Duane Voskuil ("Ethics' Dipolar Necessities and (...) Theistic Implications), and Theodore Walker Jr. ("Neoclassical Cosmology and Matthew 22:36-40). The subsection on "Evaluating Moral Practices" includes contributions from Frederick Ferrè (abstract only), Seung Gap Lee (Hope for the Earth: A Process Eschatological Eco-ethics for South Korea), Mary Elizabeth Mullino Moore (Compassion, Creativity, and Form: The Ethics of Institutions), and George W. Shields (Ruse, Altruism, and Process Philosophy). The subsection on "Ethics and Aesthetic Values" includes contributions from Stephen T. Franklin (abstract only), Brian G. Henning (Is There an Ethics of Creativity?), Mihàly Tòth (Art of Life and the Ethics of Life Forming), and Guorong Yang (Problems and Perspectives in the Emerging of Global Society). (shrink)

An examination of verbal hallucinations and thought insertion as examples of "alienated self-consciousness.".

We investigate the provability or nonprovability of certain ordinary mathematical theorems within certain weak subsystems of second order arithmetic. Specifically, we consider the Cauchy/Peano existence theorem for solutions of ordinary differential equations, in the context of the formal system RCA 0 whose principal axioms are ▵ 0 1 comprehension and Σ 0 1 induction. Our main result is that, over RCA 0 , the Cauchy/Peano Theorem is provably equivalent to weak Konig's lemma, i.e. the statement that every infinite {0, 1}-tree (...) has a path. We also show that, over RCA 0 , the Ascoli lemma is provably equivalent to arithmetical comprehension, as is Osgood's theorem on the existence of maximum solutions. At the end of the paper we digress to relate our results to degrees of unsolvability and to computable analysis. (shrink)

Stephen Salkever shows that reading Aristotle is a starting point for discussing contemporary political problems in new ways that avoid the opposition between liberal individualism and republican communitarianism, between the politics of rights and the politics of virtues. Originally published in 1990. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in (...) durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905. (shrink)

Stephen Salkever shows that reading Aristotle is a starting point for discussing contemporary political problems in new ways that avoid the opposition between liberal individualism and republican communitarianism, between the politics of rights and the politics of virtues. Originally published in 1990. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in (...) durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905. (shrink)

Science and the End of Ethics examines some of the most important positive and negative implications that science has for ethics. Addressing the negative implications first, author Stephen Morris discusses how contemporary science provides significant challenges to moral realism. One threat against moral realism comes from evolutionary theory, which suggests that our moral beliefs are unconnected to any facts that would make them true. Ironically, many of the same areas of science (e.g. evolutionary biology, neuroscience, psychology) that present difficulties (...) for moral realism point to a new ethical approach that focuses on achieving some of the key practical goals shared by ethicists. Chief among these is how to increase amicable behavior among people. (shrink)

This essay traces the interlinked origins of two concepts found in Charles Darwin's writings: "unconscious selection," and sexual selection as applied to humanity's anatomical race distinctions. Unconscious selection constituted a significant elaboration of Darwin's artificial selection analogy. As originally conceived in his theoretical notebooks, that analogy had focused exclusively on what Darwin later would call "methodical selection," the calculated production of desired changes in domestic breeds. By contrast, unconscious selection produced its results unintentionally and at a much slower pace. Inspiration (...) for this concept likely came from Darwin's early reading of works on both animal breeding and physical ethnology. Texts in these fields described the slow and unplanned divergence of anatomical types, whether animal or human, under the guidance of contrasting ideals of physical perfection. These readings, it is argued, also led Darwin to his theory of sexual selection as applied to race, a theme he discussed mainly in his book The Descent of Man. There Darwin described how the racial version of sexual selection operated on the same principle as unconscious selection. He thereby effectively reunited these kindred concepts. (shrink)

The thesis that scientists give greater weight to novel predictions than to explanations of known facts is tested against historical cases in physical science. Several theories were accepted after successful novel predictions but there is little evidence that extra credit was given for novelty. Other theories were rejected despite, or accepted without, making successful novel predictions. No examples were found of theories that were accepted primarily because of successful novel predictions and would not have been accepted if those facts had (...) been previously known. (shrink)

The evidence-based medicine movement advocates basing all medical decisions on certain types of quantitative research data and has stimulated protracted controversy and debate since its inception. Evidence-based medicine presupposes an inaccurate and deficient view of medical knowledge. Michael Polanyi’s theory of tacit knowledge both explains this deficiency and suggests remedies for it. Polanyi shows how all explicit human knowledge depends on a wealth of tacit knowledge which accrues from experience and is essential for problem solving. Edmund Pellegrino’s classic treatment of (...) clinical judgment is examined, and a Polanyian critique of this position demonstrates that tacit knowledge is necessary for understanding how clinical judgment and medical decisions involve persons. An adequate medical epistemology requires much more qualitative research relevant to the clinical encounter and medical decision making than is currently being done. This research is necessary for preventing an uncritical application of evidence-based medicine by health care managers that erodes good clinical practice. Polanyi’s epistemology shows the need for this work and provides the structural core for building an adequate and robust medical epistemology that moves beyond evidence-based medicine. (shrink)

Most clinicians take for granted a simple, reductionist understanding of medical knowledge that is at odds with how they actually practice medicine; routine medical decisions incorporate more complicated kinds of information than most standard accounts of medical reasoning suggest. A better understanding of the structure and function of knowledge in medicine can lead to practical improvements in clinical medicine. This understanding requires some familiarity with epistemology, the study of knowledge and its structure, in medicine. Michael Polanyi's theory of tacit knowing (...) is advanced as the basis for developing a more accurate understanding of medical knowledge. Tacit knowing, which explores the taken-for-granted background knowledge that underlies all human knowing, is explained in detail with a focus on its relevance for clinical medicine. The implications of recognizing tacit knowing in medicine and medical decisions are discussed. These include the ability to explain the importance of the clinical encounter in medical practice, mechanisms for analysing patient and doctor as persons, and the need for humility given the uncertainty that the tacit dimension injects into all medical decisions. This more robust medical epistemology allows clinicians to better articulate the nature and importance of patient-centred care, to avoid pitfalls inherent in reductionist approaches to medical knowledge, and to think more clearly about the relationships between medicine and health care at the individual and population levels. (shrink)

Jeremy Bentham, philosopher and reformer, is one of the most influential thinkers of the modern age. This introduction to his writings presents a representative selection of texts authoritatively restored by the Bentham Project, University College London. As well as more familiar pieces on utility, law, and politics/policy, highlights include the succinct essay “On Retrenchment” and a never-before-published treatise on sex. The volume is completed by major interpretative essays by Mark Canuel, David Lieberman, Jennifer Pitts, and Philip Schofield. The texts included (...) in the book are: -Sex -An Introduction to the Principles of Morals and Legislation, Preface and Chapters 1–5 -Place and Time -Rationale of Judicial Evidence, Specially Applied to English Practice, Book 1, Chapter 1 -Constitutional Code Rationale, Chapters 1 and 2 -Pannomial Fragments -Panopticon, or, the Inspection-House, Letters 1, 2, and 6 -Of Publicity -Manual of Political Economy, Chapters 1 and 2 -Nonsense Upon Stilts -On Retrenchment. (shrink)

“What did the President know and when did he know it?”Senator Howard Baker, Watergate hearings, 1973Why do scientists accept or reject theories? More specifically: why do they change from one theory to another? What is the role of empirical tests in the evaluation of theories?This paper focuses on a narrowly-defined question: in judging theories, do scientists give greater weight (other things being equal) to successfulnovel predictionsthan to successful deductions of previously-known facts? The affirmative answer is called the “predictivist thesis” (Maher (...) 1988).It is primarily philosophers who are interested in this question, and they have treated it mostly as a normative or logical problem. Can the writings of historians of science tell us how scientists have treated novel predictions in the past? Until recently historians have rarely addressed this point. (shrink)

This paper examines the way Charles Darwin applied his domestic breeding analogy to the practical workings of species evolution: that application, it is argued, centered on Darwin's distinction between methodical and unconscious selection. Methodical selection, which entailed pairing particular individuals for mating purposes, represented conditions of strict geographic isolation, obviously useful for species multiplication (speciation). By contrast, unconscious selection represented an open landmass with a large breeding population. Yet Darwin held that this latter scenario, which often would include multiple ecological (...) subdistricts and thus partial isolation, was better suited for speciation than were isolated conditions. At the same time, many passages in Darwin's writings that apparently portrayed phyletic evolution exclusively (these including references to unconscious selection), actually applied to speciation as well, for phyletic change in a single district could constitute a local manifestation of a larger common-descent pattern. This generic use of "phyletic" change was reflected in Darwin's deployment of the unconscious selection analogy in his published writings as well as in his dispute with Moritz Wagner over the necessity of geographic isolation for speciation. We can thus understand Darwin's otherwise puzzling declaration in The Origin of Species that unconscious selection was 'more important' than the methodical approach. (shrink)

A mass problem is a set of Turing oracles. If P and Q are mass problems, we say that P is weakly reducible to Q if every member of Q Turing computes a member of P. We say that P is strongly reducible to Q if every member of Q Turing computes a member of P via a fixed Turing functional. The weak degrees and strong degrees are the equivalence classes of mass problems under weak and strong reducibility, respectively. We (...) focus on the countable distributive lattices P w and P s of weak and strong degrees of mass problems given by nonempty Π 1 0 subsets of 2 ω . Using an abstract Gödel/Rosser incompleteness property, we characterize the Π 1 0 subsets of 2 ω whose associated mass problems are of top degree in P w and P s , respectively. Let R be the set of Turing oracles which are random in the sense of Martin-Löf, and let r be the weak degree of R. We show that r is a natural intermediate degree within P w . Namely, we characterize r as the unique largest weak degree of a Π 1 0 subset of 2 ω of positive measure. Within P w we show that r is meet irreducible, does not join to 1, and is incomparable with all weak degrees of nonempty thin perfect Π 1 0 subsets of 2 ω . In addition, we present other natural examples of intermediate degrees in P w . We relate these examples to reverse mathematics, computational complexity, and Gentzen-style proof theory. (shrink)

The authority of the intact self over the future severely demented self is based on notions of integrity and precedent autonomy. Despite criticism of this authority, the principle of precedent autonomy in the care of people with Alzheimer disease or other progressive and irreversible dementias retains its moral significance.

Let ω be the set of natural numbers. For functions f, g: ω → ω, we say f is dominated by g if f < g for all but finitely many n ∈ ω. We consider the standard “fair coin” probability measure on the space 2ω of in-finite sequences of 0's and 1's. A Turing oracle B is said to be almost everywhere dominating if, for measure 1 many X ∈ 2ω, each function which is Turing computable from X is (...) dominated by some function which is Turing computable from B. Dobrinen and Simpson have shown that the almost everywhere domination property and some of its variant properties are closely related to the reverse mathematics of measure theory. In this paper we exposit some recent results of Kjos-Hanssen, Kjos-Hanssen/Miller/Solomon, and others concerning LR-reducibility and almost everywhere domination. We also prove the following new result: If B is almost everywhere dominating, then B is superhigh, i. e., 0″ is truth-table computable from B ′, the Turing jump of B. (shrink)