In this essay, we suggest practical ways to shift the framing of crisis standards of care toward disability justice. We elaborate on the vision statement provided in the 2010 Institute of Medicine (National Academy of Medicine) “Summary of Guidance for Establishing Crisis Standards of Care for Use in Disaster Situations,” which emphasizes fairness; equitable processes; community and provider engagement, education, and communication; and the rule of law. We argue that interpreting these elements through disability justice entails a commitment to both (...) distributive and recognitive justice. The disability rights movement's demand “Nothing about us, without us” requires substantive inclusion of disabled people in decision‐making related to their interests, including in crisis planning before, during, and after a pandemic like Covid‐19. (shrink)

Affective variables have been shown to impact working memory and cognitive control. Theoretical arguments suggest that the functional impact of emotion on cognition might be mediated through shifting action dispositions related to changes in motivational orientation. The current study examined the effects of positive and negative affect on performance via direct manipulation of motivational state in tasks with high demands on cognitive control. Experiment 1 examined the effects of monetary reward on task-switching performance, while Experiment 2 examined the effects of (...) both rewards and punishments on working memory, using primary (liquid) reinforcers. In both experiments, dissociable trial-by-trial and contextual (block-related) enhancements of cognitive control during task performance were observed in relationship to motivational incentive value. Performance enhancements were equivalent in the reward and punishment conditions, but were differentially impacted by individual difference measures of trait reward and punishment sensitivity. Together, the results suggest both common and specific mechanisms by which approach and avoidance motivational states influence cognitive control, via activation of reward and punishment processing systems. (shrink)

The concepts of atoms and bonds in molecules which appeared in chemistry during the nineteenth century are unavoidable to explain the structure and the reactivity of the matter at a chemical level of understanding. Although they can be criticized from a strict reductionist point of view, because neither atoms nor bonds are observable in the sense of quantum mechanics, the topological and statistical interpretative approaches of quantum chemistry (quantum theory of atoms in molecules, electron localization function and maximum probability domain) (...) provide consistent definitions which accommodate chemistry and quantum mechanics. (shrink)

This article examines the innovations introduced to phenomenological philosophy by the Russian philosopher Gustav Gustavovich Shpet. We identify the motifs and results of Shpet's problematization of the Husserlian concept of constitution, and we develop Shpet's treatment of the source of semantic genesis as a generative experience.

This dissertation explores learned conceptions of uncertainty and risk during the period stretching approximately between 1560 and 1720. Previous historical overviews of the ideas about risk hold that pre-industrial societies viewed all worldly happenings as emanations of God's will or other forces lying beyond human control. This viewpoint is scrutinized and called into question in the dissertation through an examination of early modern Swedish sources. In order to show how earthly uncertainty was conceptualized documents dealing with actual calamities are analyzed. (...) Particular attention is paid to documents that portray man as being subjected to forces beyond his control. In early modern Sweden the questions of causality and responsibility were continuously debated according to the interests and perspectives of differing actors. The same type of occurrence could be given very different - even contradictory - interpretations. E.g. shipwrecks could be viewed as divine punishments, warnings, trials, miraculous deliverances, divine secrets, omens of coming events, or quite simply human errors. The concrete rhetorical situation determined which of them was put to use. In practical planning explanations based on God's intentions played no direct role. In a worldly perspective, fortuna was seen as a challenge that individuals were compelled to overcome by means of knowledge and virtue. Taken together, the texts serve to paint a portrait of a moral universe in which worldly events reflect the will of God, yet without relieving man of responsibility for his actions. (shrink)

_Threshold Concepts in Problem-based Learning_ provides a critical discussion and guidance for educational researchers, teachers, innovators and policy makers wanting to explore the interrelationship of PBL and threshold concepts.

The article comprises three parts. Part I contains an overview of the areas in the analysis of modern French philosophy that have been of the greatest relevance to Russian researchers over the last years. We conclude that numerous aspects of the French philosophical thought of the twentieth century are well represented in the research of Russian authors, who also point out the emerging trends in its development. Part II deals with the development of analytic philosophy in Russia within the framework (...) of such areas as “critique of bourgeois philosophy”, a purely ideological stand only nominally related to philosophy, logic, and the history of philosophy and theoretical research. Part III contains a periodization of the history of phenomenology in Russia, pointing out the most important achievements of the contemporary Russian scholars of phenomenology as well as their understanding of the essence, the problems, and the aims of phenomenological philosophy. We also indicate the tendencies within the development of the discipline in the Russian Federation. (shrink)

The COVID-19 (Coronavirus disease of 2019) pandemic has led to intense conversations about ventilator allocation and reallocation during a crisis standard of care. Multiple voices in the media and multiple state guidelines mention reallocation as a possibility. Drawing upon a range of neuroscientific, phenomenological, ethical, and sociopolitical considerations, the authors argue that taking away someone’s personal ventilator is a direct assault on their bodily and social integrity. They conclude that personal ventilators should not be part of reallocation pools and that (...) triage protocols should be immediately clarified to explicitly state that personal ventilators will be protected in all cases. (shrink)

Correct interpretation of the data from integral laboratory tests, including Thrombin Generation Test, requires biochemistry-based mathematical models of blood coagulation. The purpose of this study is to describe the experimental TGT data from healthy donors and hemophilia A and B patients. We derive a simplified ODE model and apply it to analyze the TGT data from healthy donors and HA/HB patients with in vitro added tissue factor pathway inhibitor antibody. This model allows the characterization of hemophilia patients in the space (...) of three most important model parameters. The proposed approach may provide a new quantitative tool for the analysis of experimental TGT. Also, it gives a reduced model of coagulation verified against clinical data to be used in future theoretical large-scale modeling of thrombosis in flow. (shrink)

The English language has adopted the word Tardis for something that looks simple from the outside but is much more complicated when inspected from the inside. The word comes from a BBC science fiction series, in which the Tardis is a machine for traveling in time and space, that looks like a phone booth from the outside. This paper claims that simulation models are a Tardis in a way that calls into question their transferability. The argument is developed taking Molecular (...) Modeling and Simulation as an example. There, simulation models are force fields that describe the molecular interactions and that look like simple and highly modular mathematical expressions. To make them work, they contain parameters that are adjusted to match certain data. The role of these parameters and the way they are obtained is seriously under-appreciated. It is constitutive for the model and central for its applicability and performance. Hence, the model is more than it seems so that working with adjustable parameters deeply affects the ontology of simulation models. This is particularly crucial for the transferability of the models: the information on how a model was trained is like luggage the model must carry on its voyage. (shrink)

This paper addresses a variant of the job shop scheduling problem with total tardiness minimization where task durations and due dates are uncertain. This uncertainty is modelled with intervals. Different ranking methods for intervals are considered and embedded into a genetic algorithm. A new robustness measure is proposed to compare the different ranking methods and assess their capacity to predict ‘expected delays’ of jobs. Experimental results show that dealing with uncertainty during the optimization process yields more robust solutions. A sensitivity (...) analysis also shows that the robustness of the solutions given by the solving method increases when the uncertainty grows. (shrink)

Order picking, which is collecting a set of products from different locations in a warehouse, has repeatedly been described as one of the most laborious and time-consuming internal logistic processes. Each order is issued to pick some products located at given locations in the warehouse. In this paper, we consider an order picking problem, in which a number of orders with different delivery due dates are going to be retrieved by a limited number of order pickers in multiperiods such that (...) the total tardiness is minimized. The aim is to determine a retrieval plan in terms of order batching and order picker multitrip routing as decision variables. Besides, products are arrived and replenished at the predetermined locations at different periods. Therefore, products sitting in those locations should be delivered soon to provide empty rooms for replenishment. A mixed integer linear programming formulation is proposed for this new problem. The model is optimally solved for small-size problems. For larger instances, grouping metaheuristic algorithms are proposed based on particle swarm optimization and the league championship algorithm that use group-based operators to generate reasonable batches of orders. Improvement heuristics are designed as well. The performance of the MILP formulation and metaheuristic algorithms is analyzed for different problem instances whose designs are based on real data gathered from an auto parts warehouse. Results indicate that our algorithms can stably solve large instances of the problem in a reasonable time. (shrink)

Sans prétendre faire œuvre exhaustive ni même définitive, Mariette Sineau et Evelyne Tardy se livrent à un instructif travail comparatif sur le droit des femmes dans les deux territoires francophones. Malgré toutes leurs différences, ceux-ci se montrent suffisamment proches pour soutenir la comparaison. Tous deux adoptent le code civil napoléonien (en 1866 pour le Québec pourtant cerné par la bien plus progressive common law), tous deux sont également à forte dominante catholique. Le m..

Sans prétendre faire œuvre exhaustive ni même définitive, Mariette Sineau et Evelyne Tardy se livrent à un instructif travail comparatif sur le droit des femmes dans les deux territoires francophones. Malgré toutes leurs différences, ceux-ci se montrent suffisamment proches pour soutenir la comparaison. Tous deux adoptent le code civil napoléonien (en 1866 pour le Québec pourtant cerné par la bien plus progressive common law), tous deux sont également à forte dominante catholique. Le m...