This paper explores food commoning through an ethnographic case study in Catalonia as our primary site while the Norwegian case is juxtaposed as a comparison, two agriculturally and economically different European countries. The ethnography analyses cooperation networks between organic food producers’ and consumers’ involving different nodes of community gardening initiatives, self-employed growers, local farmers and all of them under a unique cooperative integrating a community economy. The result it is a myriad of exchange practices ranging from reciprocity and barter to (...) market exchange without intermediaries through on-line platforms. Along these exchanges different options of currency intervene giving rise to novel social and cooperative relations. Similar initiatives in Norway show less variation and are less experimental regarding forms of payment but share similarities in relation to material articulations, concerns and forms of alternative practice. Although these novel forms do not represent a complete break from the more standardized supply chains, and hence from the oppositions/contradictions of production and consumption, the participants see themselves as contributing to a more general process of de-commodification of food. We explore the extent to which the meaning and moral values are mutually constituted in relation to socioeconomic exchanges and environmental caring that each person experiences based on different forms of cooperation and reciprocity. Food, we suggest, is more than a commodity on the market that we may influence through our role as consumers. It is a significant focal point connecting our lives to those of others that articulates one’s relations to society in a political manner. (shrink)

This paper explores food commoning through an ethnographic case study in Catalonia as our primary site while the Norwegian case is juxtaposed as a comparison, two agriculturally and economically different European countries. The ethnography analyses cooperation networks between organic food producers’ and consumers’ involving different nodes of community gardening initiatives, self-employed growers, local farmers and all of them under a unique cooperative integrating a community economy. The result it is a myriad of exchange practices ranging from reciprocity and barter to (...) market exchange without intermediaries through on-line platforms. Along these exchanges different options of currency intervene giving rise to novel social and cooperative relations. Similar initiatives in Norway show less variation and are less experimental regarding forms of payment but share similarities in relation to material articulations, concerns and forms of alternative practice. Although these novel forms do not represent a complete break from the more standardized supply chains, and hence from the oppositions/contradictions of production and consumption, the participants see themselves as contributing to a more general process of de-commodification of food. We explore the extent to which the meaning and moral values are mutually constituted in relation to socioeconomic exchanges and environmental caring that each person experiences based on different forms of cooperation and reciprocity. Food, we suggest, is more than a commodity on the market that we may influence through our role as consumers. It is a significant focal point connecting our lives to those of others that articulates one’s relations to society in a political manner. (shrink)

Editor's suggested further reading in BioEssays: Evolution in response to climate change: In pursuit of the missing evidence AbstractHow will fish that evolved at constant sub‐zero temperatures cope with global warming? Notothenioids as a case study Abstract.

The ability to recover from official match-play across a single and multiple matches is often considered a key factor in subsequent performance for modern professional basketball. The aims of this study were to: explore the differences in match performances between different match congestion cycles ; and identify the key performance indicators discriminating between winning and losing during different match congestion cycles. The current study indicated that scoring close to or very far away was significantly greater for winning matches separated by (...) 1- and 2-days of rest compared to consecutive matches. Additionally, shooting efficiency, and attaining Defensive Rebounds and Steals, were significant offensive and defensive KPIs that differentiated winning and losing teams. Similarly, opponent quality and match pace were important situational variables that affected match outcome during different match congestion cycles. While match location had an impact on winning following 1- and 2-days of rest, it had no impact for back-to-back matches. The current results will support coaches' offensive, defensive and recovery strategies during various match congestion cycles for a greater probability of winning NBA matches. (shrink)

IntroductionCerebral visual impairment results from damage to cerebral visual processing structures. It is the most common cause of pediatric visual impairment in developed countries and rising in prevalence in developing nations. There is currently limited understanding on how neurologic, developmental, and ophthalmic factors predict outcome for pediatric CVI.MethodA retrospective manual chart review of pediatric CVI patients seen at the tertiary pediatric hospital neurology and neuro-ophthalmology service between 2010 and 2019 was conducted. Patients were stratified into severity groups, and followed over (...) time to identify outcome predictors. Collected baseline characteristics included perinatal, genetic, developmental, and neurologic history, along with neuroimaging and fundoscopic findings on examination. Longitudinal data collected included age, seizure control, and type of therapy received. Linear mixed-effect models were used for longitudinal CVI grade outcome analysis.ResultsA total of 249 individuals spanning 779 patient visits were identified. Mean age at diagnosis was 18.8 ± 16.8 months. About 64.3% were born at term age. Perinatal history revealed hypoxic ischemic encephalopathy in 16.5%, intraventricular hemorrhage in 11.6%, and seizures in 21.7%. At presentation, 60.3% had a diagnosis of cerebral palsy and 84.7% had developmental delay. Among all subjects, 78.6% had epilepsy; 33.8% had an epileptic encephalopathy, with spasms/hypsarrhythmia being most common. Abnormal neuroimaging was present in 93.8%. Genetic anomalies were present in 26.9%. Baseline visual examination revealed no blink-to-light in 24.5%; only BTL in 34.5%, fixation/tracking in 26.5%, and optokinetic drum follow in 14.4%. Longitudinal data analysis showed that perinatal history of HIE, a positive epilepsy history, using multiple epilepsy medications, cerebral palsy, and abnormal fundoscopic findings were all negatively associated with CVI grade change over time. After controlling for significant confounders, receiving any type of therapy [early childhood intervention, physical and occupational therapy, refractive error correction or glasses] was significantly associated with longitudinal improvement in CVI grade compared to patients who did not receive any therapy, with glasses yielding the largest benefit.ConclusionThis study offers extensive insights into neurologic, developmental and ophthalmologic features in patients with moderate to severe CVI. In concordance with previous findings, aspects of perinatal history and epilepsy/seizure control may help inform severity and prognosis in the general neurology or ophthalmology clinic. Conversely, these aspects, as well as genetic and specific epilepsy traits may alert vision health care providers in the clinic to pursue visual evaluation in at-risk individuals. Longitudinal follow-up of CVI patients showed that interventional therapies demonstrated vision function improvement greater than no therapy and maturational development. (shrink)

Este artículo de revisión examina la importancia que tienen las comunidades microbianas que colonizan los ambien­tes y equipos de procesado de alimentos formando biopelículas o biofilms en la persistencia microbiana en la industria alimen­taria y consecuentemente, en la seguridad y la calidad de los alimentos. La atención se centra especialmente en biopelículas formadas por microorganismos no deseados, es decir, microor­ganismos alterantes y patógenos. Se presenta información so­bre la variabilidad intraespecífica en la formación, la ecología y la arquitectura de las biopelículas, (...) y los factores que influyen en su formación. Asimismo, se resume la información disponible sobre nuevos agentes o estrategias para el control de la forma­ción o eliminación de biopelículas. (shrink)

Experimental studies show that some corvids, apes, and rodents possess a common long-term memory system that allows them to take goal-directed actions on the basis of absent spatiotemporal contexts. In other words, evidence supports the hypothesis that Episodic Memory —far from being uniquely human— has evolved as a cross-species meaning making system. However, within this zoosemiotic breakthrough, neurocognitive studies now struggle characterizing the relations between teleological factors and phenomenological factors that would account for the episodic behavior displayed by these living (...) beings. Within such field, this paper identifies four epistemological gaps —the ‘Nagelian’, ‘de Waalian’, ‘Chomskyan’, and ‘semiotic’ gaps—, making a case for the need of a future biosemiotic model of Alloanimal Episodic Memory to come into the equation. As a whole, I conclude that experimental developments in AEM research, and philosophical advancements in biosemiotics could converge through the concept of semiosis. Introducing the latter would account for animal episodic agency as a causal influence and continuity between the above relations, outclassing the reductionist and Cartesian separation between ‘external’ bodily behavior and ‘internal’ computational operations. (shrink)

The actual “crisis of care” in western societies highlights the limits of a sex/gender based citizenship and the persistence of the subordination of women. The fact that women are responsible for the provision of care in domestic units has never been a matter of difference but a matter of subordination against which we have developed legal strategies, such as anti-discrimination law, and political strategies, such as increasing the presence of women in decision-making. The paper shows some of these strategies and (...) their limits and argues that we need to resignify citizenship in a way that includes human dependency and the webs of relationships, both local and global, this dependency creates. (shrink)

Student-centered pedagogy has been embraced by many feminist practitioners and educational theorists as an antidote to more “traditional” or “masculinist” forms of classroom relations, epistemological constructs, and theories of self. I will show that the margin-center schema, student-centered pedagogy’s foundational metaphor, undermines feminist projects when applied to teacher-student relations. Although the margin-center schema has been a useful diagnostic tool in feminist theory, it operates prescriptively in student-centered pedagogy. Student-centered pedagogy designates teachers’ “proper place” at the margins of classroom life, a (...) place that echoes bygone visions of domestic femininity. This paper is simultaneously a critique of student-centered pedagogy and a recuperative project to dislodge the work of John Dewey from the teacher-centered/student-centered binary. (shrink)

The scope and role of theological bioethics has become a growing controversial topic. For instance, some bioethicists have adopted a strong stance on the meaning of “Christian bioethics,” as not ex...

La noción de interpretación desarrollada en el racionalismo crítico de Karl R. Popper muestra atributos específicos que la distinguen de modo sustancial de la interpretación constitutiva de la experiencia que tanto N. R. Hanson como Th. Kuhn defienden en sus respectivas propuestas. Se muestra que la interpretación del modelo popperiano queda atrapada en una epistemología de corte empirista que la separa de modo radical de toda hermenéutica filosófica. The notion of interpretation developed in the critical rationalism of Karl R. Popper (...) displays specific attributes that substantially distinguish it from the constituent interpretation of experience defended in both N. R. Hanson and T. Kuhn proposals. The article shows that the interpretation of Popper's model is trapped in an empiricist epistemology that radically separates it from all hermeneutic philosophy. (shrink)

McLeod's Conscience in Reproductive Health Care offers a number of valuable contributions to the literature, both within and beyond reproductive care. In this commentary, I begin by discussing two potential applications of her argument that healthcare professionals—specifically, those "who are charged with gatekeeping access to healthcare services" —have a fiduciary duty of loyalty to prioritize the interests of their patients over their own. Then, I turn to a couple of concerns one might raise about extending this fiduciary duty to pharmacists (...) who function as gatekeepers of reproductive services. Finally, I pose some questions about the ways in which McLeod conceives of the harms and wrongs of... (shrink)

Guido Löhr's recent article makes several insightful and productive suggestions about how to proceed with the empirical study of collective action. However, their critique of the conclusions drawn in Gomez-Lavin & Rachar (2022) is undermined by some issues with the interpretation of the debate and paper. This discussion article clears up those issues, presents new findings from experiments developed in response to Löhr's critiques, reflects on the role of experimental research in the development and refinement of philosophical theories, and adds (...) to Löhr's suggestions about the path forward. (shrink)

BackgroundThis article aims to contribute to a better conceptualization of pain and suffering by providing non-essential and non-naturalistic definitions of both phenomena. Contributions of classical evidence-based medicine, the humanistic turn in medicine, as well as the phenomenology and narrative theories of suffering and pain, together with certain conceptions of the person beyond them are critically discussed with such purpose.MethodsA philosophical methodology is used, based on the review of existent literature on the topic and the argumentation in favor of what are (...) found as better definitions of suffering and pain.ResultsPain can be described in neurological terms but cognitive awareness, interpretation, behavioral dispositions, as well as cultural and educational factors have a decisive influence on pain perception. Suffering is proposed to be defined as an unpleasant or even anguishing experience, severely affecting a person at a psychophysical and existential level. Pain and suffering are considered unpleasant. However, the provided definitions neither include the idea that pain and suffering can attack and even destroy the self nor the idea that they can constructively expand the self; both perspectives can b e equally useful for managing pain and suffering, but they are not defining features of the same. Including the existential dimension in the definition of suffering highlights the relevance of suffering in life and its effect on one’s own attachment to the world. An understanding of pain and suffering life experiences is proposed, meaning that they are considered aspects of a person’s life, and the self is the ever-changing sum of these experiences.ConclusionsThe provided definitions will be useful to the identification of pain and suffering, to the discussion of how to relieve them, and to a better understanding of how they are expressed and experienced. They lay the groundwork for further research in all these areas, with the twofold aim of a) avoiding epistemological mistakes and moral injustices, and b) highlighting the limitations of medicine in the treatment of suffering and pain. (shrink)

This paper examines from a historical perspective Tarski's 1936 essay, "On the concept of logical consequence." I focus on two main aims. The primary aim is to show how Tarski's definition of logical consequence satisfies two desiderata he himself sets forth for it: (1) it must declare logically correct certain formalizations of the -rule and (2) it must allow for variation of the individual domain in the test for logical consequence. My arguments provide a refutation of some interpreters of Tarski, (...) and notably John Etchemendy, who have claimed that his definition does not satisfy those desiderata. A secondary aim of the paper is to offer some basic elements for an understanding of Tarski's definition in the historical logico-philosophical context in which it was proposed. Such historical understanding provides useful insights on Tarski's informal ideas on logical consequence and their internal cohesion. (shrink)

The main aim of this paper is to point out that Davidsonian and Fregean theories of quotation do not accommodate certain facts about disquotation. A second aim is to dispel some errors of interpretation in a common Davidsonian reading of Tarski's claims about quotation. This allows a correct exegesis of Tarski's view, which is then seen not to be affected by the arguments usually adduced against the view wrongly attributed to Tarski. Finally, a Tarskian view is proposed of some problems (...) about quotation not addressed by Tarski. (shrink)

This paper analyses Merleau‑Ponty’s gestural theory focusing on the ontological and epistemological role attributed to the expressive movements of the lived body. The first section argues that Merleau‑Ponty’s phenomenology recognises movement as a primordial phenomenon from which language and thought emerge. This theorisation allows us to identify a type of logos that grants a specific content, sense and value to bodily movements, here conceptualised as a “kin(aesth)etic logos”. The second section of the paper offers a categorisation of different gestures—perceptive, reflexive, (...) habitual and verbal gestures—which show how the kin(aesth)etic logos is actualised in a myriad of daily activities. (shrink)

Timothy Williamson’s potentially most important contribution to epistemicism about vagueness lies in his arguments for the basic epistemicist claim that the alleged cut-off points of vague predicates are not knowable. His arguments for this are based on so-called ‘margin for error principles’. This paper argues that these principles fail to provide a good argument for the basic claim. Williamson has offered at least two kinds of margin for error principles applicable to vague predicates. A certain fallacy of equivocation seems to (...) underlie his justification for both kinds of principles. Besides, the margin for error principles of the first kind can be used in the derivation of unacceptable consequences, while the margin for error principles of the second kind can be shown to be compatible with the falsity of epistemicism, under a number of assumptions acceptable to the epistemicist. (shrink)

Some arguments against David Lewis’s modal realism seek to exploit apparent inconsistencies between it and anthropic reasoning. A recent argument, in particular, seeks to exploit an inconsistency between modal realism and typicality anthropic premises, premises common in the literature on physical multiverses, to the effect that observers who are like human observers in certain respects must be typical in the relevant multiverse. Here I argue that typicality premises are not applicable to the description of Lewis’s metaphysical multiverse, where the proportions (...) of metaphysically possible observers possessing the pertinent properties can be independently established by metaphysical reasoning. However, other kinds of reasonable anthropic premises can be seen to be consistent with and usable within modal realism. (shrink)

Presentación del editor: "Es sabido que un tema acaparaba la atención de los pensadores a principios del siglo XX: la historia. Mientras tanto entraba en escena el personalismo filosófico, corriente interesada en rescatar a la persona de las ideologias. Ocupando un lugar propio dentro del personalismo, no siempre en acuerdo con los demás personalistas, destaca la figura de Maurice Nédoncelle. Su filosofia de la persona y del amor plasmada en su libro sobre la reciprocidad de las conciencias es cada vez (...) más conocida; pero lo que no habia sido analizado hasta ahora es su pensamiento sobre la historia. con este estudio se da a conocer por primera vez la filosofía de la historia de Maurice Nédoncelle. La interpretación propuesta por el autor es quizás novedosa y hasta un poco audaz, pero está convencido de que Nédoncelle profesó una filosofía de la historia y de que muchas de sus afrimaciones filosóficas brotan del deseo de dar respuesta a las interrogantes sobre la historia en la que convergían los intereses de otros filósofos. Lo que interesará al lector es descubrir el gran valor de una reflexión sobre el sentido del devenir temporal que pone al centro las relaciones interpersonales. (shrink)

Lorenzo Sacconi's The Social Contract of the Firm (Berlin, Springer, 2000) is a major contribution to the normative theory of the firm. It contains a full-fledged contractarian explanation of the role of Corporate Codes of Ethics. Sacconi proposes a game-theoretical model of the normative structure of the firm, including explicit and implicit contracts binding the members of the organisation, and the so-called constitutional contract: the hypothetical agreement that sets the basic co-operative structure in which the organisation consists. While Sacconi's theory (...) is sound and full of suggestions, it is doubtful whether it completely grasps the nature of organisational ethics. In presenting organisations as the product of an agreement among self-interested individuals, the model does not account for the social and systemic embeddedness of business institutions. This paper points to several shortcomings of Sacconi's view, and explores alternative understandings of a contractarian morality as applied to business ethics. (shrink)

Logic is formal in the sense that all arguments of the same form as logically valid arguments are also logically valid and hence truth-preserving. However, it is not known whether all arguments that are valid in the usual model-theoretic sense are truthpreserving. Tarski claimed that it could be proved that all arguments that are valid (in the sense of validity he contemplated in his 1936 paper on logical consequence) are truthpreserving. But he did not offer the proof. The question arises (...) whether the usual modeltheoretic sense of validity and Tarski's 1936 sense are the same. I argue in this paper that they probably are not, and that the proof Tarski had in mind, although unusable to prove that model-theoretically valid arguments are truth-preserving, can be used to prove that arguments valid in Tarski's 1936 sense are truth-preserving. (shrink)

Integrated approaches in the ethical decision-making (EDM) and practically wise decision-making literature are emerging as alternative perspectives to management theories that conceptualize decision-making in a rationalist and value-free manner. However, more dialogue between both perspectives and qualitative research that applies them is required. In addition, there is a need for empirical analysis on business engagement in the face of grand challenges in developing countries. This paper proposes an integrated practically wise EDM framework to study how Colombian councilors who, in 2013, (...) voted for or against the merger between the Colombian state-owned company UNE and the Swedish multinational Millicom interpret this decision and its public impact. Qualitative semi-structured interviews were conducted with a voluntary sample of 18 of 21 councilors. Supporters of the UNE-Millicom merger expressed open-mindedness, seeing the merger as a means to achieve justice. On the contrary, the merger’s opponents expressed circumspection, doubting that Millicom’s intentions really leaned toward justice. We conclude that practical wisdom—embodied by both supporters and detractors—fosters an understanding of EDM beyond what leaders should not do. It also includes a democratic and balanced deliberation on what leaders think they should do to promote the common good. (shrink)

The purpose of this paper is to examine some passages of Tarski‘s paper ’On the concept of logical consequence’ and to show that some recent readings of those passages are wrong. John Etchemendy has claimed that in those passages Tarski gave an argument purporting to show that the notion of logical consequence defined by him (as opposed to some pretheoretic notion of logical consequence) possesses certain modal properties. Etchemendy further claims that the argument he attributes to Tarski is fallacious. Some (...) of Etchemendy’s critics have granted him that Tarski did give an argument purporting to show that the defined notion possesses certain modal properties ; but they have claimed that Tarski’s argument was not a fallacious one. I will show that both Etchemendy and his critics are wrong; in the relevant passages, Tarski did not offer (nor did he intend to offer) an argument that the defined notion of logical consequence possesses any modal properties. (shrink)

In the three previous chapters we mapped out Žižek’s philosophical thinking—territory in which we situated his critique of “postmodern historicism”, as well as his bleak assessment of the struggles of the contemporary left. We have also examined his theory of revolution and his recourse to Christianity as a paradigm for communist brotherhood that may well function as a real alternative to capitalism. Throughout this interpretative and reconstructive exercise, I subjected Žižek’s proposals to a hail of critical questions and commentary, on (...) which I have not yet adequately elaborated. This will precisely be the task that I will undertake in the last two chapters of the book. Our starting point will be to pick up on some of Žižek’s central ideas with which I agree, while taking them to a philosophical terrain that will help us avoid their fatidic consequences: the avowal of subjectless revolutions. I am referring to two Žižekian motifs that are worth reconsidering: the ontology of incompleteness and the universal dimension of politics. Our goal is to “de-Lacanize” those concepts and to see how they could operate in a different kind of political ontology that does not resort to the figure of a transcendental subject, and that renders power as an inescapable condition of experience. I would then like to articulate the two aforementioned concepts with a third one—the Gramscian notion of hegemony—but read alongside the work of Ernesto Laclau and Chantal Mouffe. The purpose of this exercise is to create the conceptual conditions to formulate an emancipatory theory of democracy—a matter that will be taken up in the following chapter. (shrink)

This article is a slightly modified version of the first part of Chapter 4 of Revoluciones sin sujeto. Slavoj Žižek’s y la crítica del historicismo posmoderno (Madrid: Akal, 2015) translated by Douglas Kristopher Smith and Nicolas Lema Habash. This text seeks to overcome the scission between Slavoy Žižek and Michel Foucault by challenging the notion that Foucault lacks an ontology of power, beyond contingent historical processes. By exposing the underlying Nietzschean relational ontology of struggle—as distinct from a fundamental, positive grounding—in (...) Foucault’s work, the piece shows how this aspect has been largely misunderstood—including by Žižek himself. Furthermore, it demonstrates how this agonistic ontology of human experience can serve to shed light on Žižek’s notion of the incompleteness of the subject by bringing it into the realm of politics. (shrink)

Resumen: Este artículo destaca el término Pietät en la obra de Hegel como concepto fundamental para una filosofía que abre varios campos para la teoría social, confrontado de manera inexorable al positivismo o “materialismo naturalista” desde el que se le hacen reconocidas críticas a Hegel en las ciencias sociales. Mediante este término Hegel describe una evolución social buscando la sustancia de cada una de las etapas que la comprenden, en particular, en occidente. Primero, se expone el lugar en la obra (...) de Hegel en que aparece el término Pietät como inicio de esa evolución histórico-social. Luego, se expone el destino de esa evolución como completud de la subjetividad-humana. Finalmente, se resumen los campos de investigación que abre el estudio de este término de Pietät, que se torna concepto en Hegel.: This article stresses the term Pietät in Hegel's work as a fundamental concept to a philosophy that open several fields on social theory facing inexorably positivism or “naturalistic materialism” from which have been made renown critics to Hegel on social science. Through this term, Hegel describes a social evolution looking for the substance of each one of the stages that comprise it, particularly in the West. This paper first exposes the place in the Hegel’s work where the term Pietät appears as the beginning of that social evolution. Then it is exposed the destiny of that evolution as completeness of human-subjectivity. Finally, is specified the fields of research open by the study of the term Pietät, that in Hegel is turned to concept. (shrink)

The INBIOSA project brings together a group of experts across many disciplines who believe that science requires a revolutionary transformative step in order to address many of the vexing challenges presented by the world. It is INBIOSA’s purpose to enable the focused collaboration of an interdisciplinary community of original thinkers. This paper sets out the case for support for this effort. The focus of the transformative research program proposal is biology-centric. We admit that biology to date has been more fact-oriented (...) and less theoretical than physics. However, the key leverageable idea is that careful extension of the science of living systems can be more effectively applied to some of our most vexing modern problems than the prevailing scheme, derived from abstractions in physics. While these have some universal application and demonstrate computational advantages, they are not theoretically mandated for the living. A new set of mathematical abstractions derived from biology can now be similarly extended. This is made possible by leveraging new formal tools to understand abstraction and enable computability. [The latter has a much expanded meaning in our context from the one known and used in computer science and biology today, that is "by rote algorithmic means", since it is not known if a living system is computable in this sense.] Two major challenges constitute the effort. The first challenge is to design an original general system of abstractions within the biological domain. The initial issue is descriptive leading to the explanatory. There has not yet been a serious formal examination of the abstractions of the biological domain. What is used today is an amalgam; much is inherited from physics and there are many new abstractions from advances in mathematics. Interspersed are abstractions, concepts and underlying assumptions “native” to biology and distinct from the mechanical language of physics and computation as we know them. A pressing agenda should be to single out the most concrete and at the same time the most fundamental process-units in biology and to recruit them into the descriptive domain. Therefore, the first challenge is to build a coherent formal system of abstractions and operations that is truly native to living systems. Nothing will be thrown away, but many common methods will be philosophically recast, just as in physics relativity subsumed and reinterpreted Newtonian mechanics. -/- This step is required because we need a comprehensible, formal system to apply in many domains. Emphasis should be placed on the distinction between multi-perspective analysis and synthesis and on what could be the basic terms or tools needed. The second challenge is relatively simple: the actual application of this set of biology-centric ways and means to cross-disciplinary problems. In its early stages, this will seem to be a “new science”. This White Paper sets out the case of continuing support of Information and Communication Technology for transformative research in biology and information processing centered on paradigm changes in the epistemological, ontological, mathematical and computational bases of the science of living systems. Today, curiously, living systems cannot be said to be anything more than dissipative structures organized internally by genetic information. There is not anything substantially different from abiotic systems other than the empirical nature of their robustness. We believe that there are other new and unique properties and patterns comprehensible at this bio-logical level. The report lays out a fundamental set of approaches to articulate these properties and patterns, and is composed as follows. -/- Sections 1 through 4 are incipient. Section 5 describes the issues affecting Integral Biomathics and Section 6 -- the aspects of the Grand Challenge we face with this project. Section 7 contemplates the effort to formalize a General Theory of Living Systems from what we have today. The goal is to have a formal system, equivalent to that which exists in the physics community. Here we define how to perceive the role of time in biology. Section 8 describes the initial efforts to apply this general theory of living systems in many domains, with special emphasis on crossdisciplinary problems and multiple domains spanning both “hard” and “soft” sciences. The expected result is a coherent collection of integrated mathematical techniques. Section 9 discusses the first two test cases, project proposals, of our approach. They are designed to demonstrate the ability of our approach to address “wicked problems” which span across physics, chemistry, biology, societies and societal dynamics. The solutions require integrated measurable results at multiple levels known as “grand challenges” to existing methods. Finally, Section 10 adheres to an appeal for action, advocating the necessity for further long-term support of the INBIOSA program. -/- The report is concluded with preliminary non-exclusive list of challenging research themes to address, as well as required administrative actions. The efforts described in the ten sections of this White Paper will proceed concurrently. Collectively, they describe a program that can be managed and measured as it progresses. (shrink)

The INBIOSA project brings together a group of experts across many disciplines who believe that science requires a revolutionary transformative step in order to address many of the vexing challenges presented by the world. It is INBIOSA’s purpose to enable the focused collaboration of an interdisciplinary community of original thinkers. This paper sets out the case for support for this effort. The focus of the transformative research program proposal is biology-centric. We admit that biology to date has been more fact-oriented (...) and less theoretical than physics. However, the key leverageable idea is that careful extension of the science of living systems can be more effectively applied to some of our most vexing modern problems than the prevailing scheme, derived from abstractions in physics. While these have some universal application and demonstrate computational advantages, they are not theoretically mandated for the living. A new set of mathematical abstractions derived from biology can now be similarly extended. This is made possible by leveraging new formal tools to understand abstraction and enable computability. [The latter has a much expanded meaning in our context from the one known and used in computer science and biology today, that is "by rote algorithmic means", since it is not known if a living system is computable in this sense (Mossio et al., 2009).] Two major challenges constitute the effort. The first challenge is to design an original general system of abstractions within the biological domain. The initial issue is descriptive leading to the explanatory. There has not yet been a serious formal examination of the abstractions of the biological domain. What is used today is an amalgam; much is inherited from physics (via the bridging abstractions of chemistry) and there are many new abstractions from advances in mathematics (incentivized by the need for more capable computational analyses). Interspersed are abstractions, concepts and underlying assumptions “native” to biology and distinct from the mechanical language of physics and computation as we know them. A pressing agenda should be to single out the most concrete and at the same time the most fundamental process-units in biology and to recruit them into the descriptive domain. Therefore, the first challenge is to build a coherent formal system of abstractions and operations that is truly native to living systems. Nothing will be thrown away, but many common methods will be philosophically recast, just as in physics relativity subsumed and reinterpreted Newtonian mechanics. -/- This step is required because we need a comprehensible, formal system to apply in many domains. Emphasis should be placed on the distinction between multi-perspective analysis and synthesis and on what could be the basic terms or tools needed. The second challenge is relatively simple: the actual application of this set of biology-centric ways and means to cross-disciplinary problems. In its early stages, this will seem to be a “new science”. This White Paper sets out the case of continuing support of Information and Communication Technology (ICT) for transformative research in biology and information processing centered on paradigm changes in the epistemological, ontological, mathematical and computational bases of the science of living systems. Today, curiously, living systems cannot be said to be anything more than dissipative structures organized internally by genetic information. There is not anything substantially different from abiotic systems other than the empirical nature of their robustness. We believe that there are other new and unique properties and patterns comprehensible at this bio-logical level. The report lays out a fundamental set of approaches to articulate these properties and patterns, and is composed as follows. -/- Sections 1 through 4 (preamble, introduction, motivation and major biomathematical problems) are incipient. Section 5 describes the issues affecting Integral Biomathics and Section 6 -- the aspects of the Grand Challenge we face with this project. Section 7 contemplates the effort to formalize a General Theory of Living Systems (GTLS) from what we have today. The goal is to have a formal system, equivalent to that which exists in the physics community. Here we define how to perceive the role of time in biology. Section 8 describes the initial efforts to apply this general theory of living systems in many domains, with special emphasis on crossdisciplinary problems and multiple domains spanning both “hard” and “soft” sciences. The expected result is a coherent collection of integrated mathematical techniques. Section 9 discusses the first two test cases, project proposals, of our approach. They are designed to demonstrate the ability of our approach to address “wicked problems” which span across physics, chemistry, biology, societies and societal dynamics. The solutions require integrated measurable results at multiple levels known as “grand challenges” to existing methods. Finally, Section 10 adheres to an appeal for action, advocating the necessity for further long-term support of the INBIOSA program. -/- The report is concluded with preliminary non-exclusive list of challenging research themes to address, as well as required administrative actions. The efforts described in the ten sections of this White Paper will proceed concurrently. Collectively, they describe a program that can be managed and measured as it progresses. (shrink)

Resumen Debido a la polisemia que la complejidad exhibe, se pretenden exponer las distintas posturas, definiciones, descripciones y debates acerca de esta, a la luz de lo descrito por Carlos Maldonado, Edgar Morin, Ilya Progogine, Murray Gell-Mann, Leonardo Rodríguez y Julio Aguirre, quienes comportan un principio dialógico y translúcido, que integraría la lógica clásica teniendo en cuenta sus límites de facto y de jure, que además llevaría en sí el principio de la Unitas Multiplex, que escapa a la unidad abstracta (...) por lo alto y por lo bajo. Luego de la presentación de las posturas de los autores mencionados se pasa a describir los encuentros y desencuentros que de estos aparecen sobre este concepto; y finalizar al proponer una definición y caracterización personal de la complejidad.Due to the polysemy of Complexity, it is intended to expose different postures, definitions, descriptions and debates about It, in the light of what was described by Carlos Maldonado, Edgar Morin, Ilya Prigogine, Murray Gell-Mann, Leonardo Rodríguez and Julio Aguirre. For them it implies a dialogical and translucent principle that would integrate classical logic considering its de facto and de jure limits, and that in addition would take in himself the principle of Unitas Multiplex that escapes to the abstract unity by the high and by the low. After the presentation of the positions of the mentioned authors the paper goes on to describe encounters and disagreements about this concept finally proposing a definition and characterization of complexity. (shrink)

Dans cet ouvrage, Jacques Mestre, qui est professeur à la Faculté de droit d'Aix-Marseille, porte un regard résolument optimiste sur les choses de la vie et l'avenir de notre Humanité. Il a choisi de le faire en une triple qualité. D'abord en sa qualité d'enseignant. Animé, après plus de trente ans d'exercice professionnel, d'une passion toujours intacte pour ce superbe métier d'ouverture et de transmission. Mais soucieux également de voir les jeunes trouver leur place, avec tout le bonheur qu'ils méritent, (...) dans une société difficile, à la fois libérée et exigeante, audacieuse et craintive. Ensuite en tant que juriste. Observant ici que nombre de questions fondamentales se posent aujourd'hui, de manière très concrète, en termes juridiques. Et désireux que le Droit, souvent présenté comme ardu et technique, et qui est, en réalité, une matière simple, soit dès lors accessible à tous, et particulièrement à celles et ceux qui ont soif de réflexion et de dialogue. Enfin en tant que citoyen de base, immergé, comme tant d'autres, dans un monde qui le dépasse et, parfois même, l'angoisse. Et pourtant convaincu que ce monde recèle en lui des trésors de passion et d'enthousiasme, d'intelligence et de beauté, susceptibles de le préserver du pire et de l'orienter vers le tout meilleur... À condition encore que ces trésors ne disparaissent pas sous les préoccupations quotidiennes, et qu'ils puissent librement s'exprimer! L'auteur se propose donc de leur donner la parole, à la manière d'un rapporteur de synthèse qui, à la fin d'un colloque, s'efforcerait de rassembler tous les éléments positifs présentés par les autres pour que l'essentiel soit mis en lumière, et permette à chacun, à la place qui lui revient, de se tourner avec confiance vers l'avenir... (shrink)