The paper aims to make a contribution to semiotic research on the future by bringing together various approaches that deal with the relationship humans have with the future. More specifically, the paper concentrates on anticipation viewed as an activity that is based on modelling the (un)desired future as suggested by Nikolai Bernstein. The model-based approach to anticipation allows drawing connections between the psychophysiological and semiotically mediated forms of anticipation on the one hand, and between individual and collective forms of anticipation (...) on the other hand. With these aims in mind, the paper offers a sketch of a semiotic approach to the future that is based on the framework of semiotic modelling systems, i.e. views the future in terms of models of it and the semiotic resources and processes involved in the model-building. As the semiotically mediated models of the future circulating in a culture can become collectively shared means of cognizing and anticipating some futures, it is possible to talk about a collective anticipation, analogous to Juri Lotman’s cultural semiotic notion of collective memory. Accordingly, premediation, a future-oriented media practice outlined by Richard Grusin, is viewed as an example of collective anticipation. In addition to tracing the mechanisms of anticipation from its individual organismic to semiotically mediated collective forms, the paper foregrounds also the two fundamental problems that run across the diverse theoretical perspectives brought together within the approach: the individual and collective agency in future-making and the affective dimension of anticipation. (shrink)

The ArgumentMicroscopical consideration played a crucial role in German physiology in the period of, grosso modo, 1780–1830. Specifically, a conception of material change was established, according to which all life is grounded in the process of the generation of microscopical forms out of an amorphous, primitive generative substance. Embryological development, tissue growth, and the generation of microorganisms were all considered to be the manifestation of this fundamental developmental process. In contrast to the common historiography, I try to understand Theodor Schwann's (...) 1838 discovery of the cell theory in terms of the epistemological categories he applied to the prevailing conceptions of life and living matter. I argue that Schwann was able to discern cells not because of any superior microscopical methods, but rather as part of his wider investigative endeavor to explicate life processes according to specific causal agents. I argue that Schwann was able to demonstrate the existence of cells only when he considered animal tissues in terms of a causal relation between specific material agents and their effect, that is, the developmental history of tissue. (shrink)

Traditionally, autoimmune disease has been considered to be a case of false recognition; the immune system mistakenly identifies 'self' tissues as foreign, attacking them thus causing damage and malady. Accordingly, the history of autoimmunity is usually told as part ot the history of immunology, that is, of theories and experiments relating to the ability of the immune system to discriminate between self and nonself. This paper challenges this view, claiming that the emergence of the notion of autoimmunity in the 1950s (...) must be considered as part of a long develolpment in thought about pathology throughout the twentieth century, namely the conceptualisaiton of disease as a reactive and self-destructive process. During the first part of the twentieth century this notion became one of the cornerstones of pathology and was increasingly employed for the explanation of the non-infections, slow-burning diseases. Thus, the category of chronic disease had been defined anew, now encompassing all those diseases characterised by a persistent inflammatory process. Inflammation, in turn, was conceived as double-eged physiological mechanism, which was usually the direct mediator of damage, of the essence of disease. The paper also shows how this kind of analysis could emable a unified historical discussion of autoimmunity and allergy, hitherto considered to have distinct conceptual origins. (shrink)

We applaud Ray and Cooper (2024) for emphasizing environmental health as a bioethics issue. As a team of interdisciplinary pediatric researchers and providers who are part of an institutional clima...

Estonia has successfully created a digital society within the past 2 decades. It is best known for its eGovernment achievements, but it is also home for four unicorn star-ups. While the state is aiming to attract tech investments with e-Residency program and has recently started to invest into protecting national IP and safeguarding data from cybercrime by applying blockchain technology and creating its “digital embassy” in Luxembourg, emerging technologies such as and applications of artificial intelligence but also internet of things (...) have posed the question on legal regulation and standardization. The dilemma, however, seems to be that since the new technologies, such artificial intelligence is much more overwhelming phenomenon than e-governance and presumably, before deciding the legal standards, the political and economic strategies that go beyond the e-governance should be set. (shrink)

Persons with aphasia suffer from a loss of communication ability as a consequence of a brain injury. A small strand of research indicates effec- tiveness of dialogic interventions for communication development for persons with aphasia, but a vast amount of research studies shows its effectiveness for other target groups. In this paper, we describe the main parts of the hitherto technological development of an application named Dialogica that is (i) aimed at facilitating increased communicative participation in dialogic settings for persons (...) with aphasia and other communication disorders, (ii) based on comput- er game technology as well as on theory in dialogic education and argumenta- tion theory, and (iii) designed for mobile devices with larger screens. (shrink)

In this paper, we introduce the notion of $${\textbf{K}} $$ -rank, where $${\textbf{K}} $$ is a strong amalgamation Fraïssé class. Roughly speaking, the $${\textbf{K}} $$ -rank of a partial type is the number “copies” of $${\textbf{K}} $$ that can be “independently coded” inside of the type. We study $${\textbf{K}} $$ -rank for specific examples of $${\textbf{K}} $$, including linear orders, equivalence relations, and graphs. We discuss the relationship of $${\textbf{K}} $$ -rank to other ranks in model theory, including dp-rank and (...) op-dimension (a notion coined by the first author and C. D. Hill in previous work). (shrink)

The American Journal of Bioethics, Volume 11, Issue 12, Page 30-31, December 2011.

T‐lymphocyte recognition, activation and function involve anumber of T‐cell‐specific surface proteins in addition to the receptor for antigen. The structure, function and genetic analysis of four of these T‐cell differentiation antigens are discussed.

In this paper, we describe technological advances for supporting persons with aphasia in philosophical dialogues about personally relevant and contestable questions. A computer game-based application for iPads is developed and researched through Living Lab inspired workshops in order to promote the target group’s communicative participation during group argumentation. We outline some central parts of the background theory of the application and some of its main features, which are related to needs of the target group. Methodological issues connected to the design (...) and use of Living Labs with persons with aphasia are discussed. We describe a few problems with researching development of communicative participation during group argumentation using an app assisted intervention for the target group and suggest some possible solutions. (shrink)

We study the preservation of certain properties under products of classes of finite structures. In particular, we examine indivisibility, definable self-similarity, the amalgamation property, and the disjoint n-amalgamation property. We explore how each of these properties interacts with the lexicographic product, full product, and free superposition of classes of structures. Additionally, we consider the classes of theories which admit configurations indexed by these products. In particular, we show that, under mild assumptions, the products considered in this article do not yield (...) new classes of theories. (shrink)

Construction process stages are argued to be vulnerable to the prevalence of corrupt practices. However, the validity of this argument has not been empirically explored in the extant literature of construction management. Therefore, this study examines the stages of the construction process susceptibility to corruption and its most prominent forms of corrupt activities. A total of forty-four project-related professionals were involved in an expert survey to assess such susceptibilities and the criticality of the identified corrupt activities at each stage. A (...) comparative study of expert views from developing regions against experts from developed regions is conducted. Expert scoring results revealed that three stages are most susceptible, namely: project execution, pre-qualification and tender stages. Such results were confirmed by application of the Mann–Whitney U test statistics tool, showing wide disparities in seven out of eleven identical stages. This study is intended to incite polemic discussions and greater empirical, evidence-based research from scholars in both developed and developing countries. This study adds to the extant literature corruption-related works on the construction process through deeper understanding of the dynamic nature of corrupt practices involved in the stages of the construction process in developing countries. Practically, it intends to offer a veritable plethora of information on the critical stages of the construction process for industry practitioners, policymakers and anti-corruption bodies to careen their attention towards the fight against corruption. (shrink)

If today the archaeological investigation of Graeco-Roman sites no longer begins with the wholesale destruction of the late antique strata, much of the credit should go to the exemplary American excavations conducted from 1931 onwards in the Athenian agora. And yet, in part because the late antique city's heart shifted eastwards, away from the classical agora towards an area that has been only partially excavated, we still have no monograph on late Roman and early Byzantine Athens—and that despite the current (...) fashion for historico-archaeological studies of the evolving urban tissue. As for the even newer fashion for archaeological survey, which has produced impressive results in neighbouring Boeotia, it will inevitably pass the immediate Athens region by, thanks to its extensive urbanization in the past thirty years. It is worth remembering, though, that if a quarter of the Athenian's horizon is the familiar and all-important sea, three quarters are mountain. On Parnes, Pentelicus and Hymettus, with their fortresses, watch-towers and sacred caves, one can still catch echoes of a lost rural world in constant interaction with the nearby city. As a contribution to the research on ‘city and countryside’ that is the natural synthesis of urban history and rural survey, it seems worthwhile to consider what can presently be known about the relation between late antique Athens and its neighbouring mountains. (shrink)

Maslow, A. A. Towards a humanistic biology.--Murphy, G. The inside and the outside of creativity.--Stacy, D. L. Art and human creativity.--Parnes, S. J. Creative potential and the educational experiment.--Laszlo, E. "Reverence for natural systems."--McInnis, N. Gestalt ecology.--Harman, W. H. Alternate futures and habitability.--Smith, R. A. Synergistic organizations.--Reiser, O. L. The cosmic lens, the galactic disc, and the archetypal holograms.--Smith, R. A. "Unibutz."--Stulman, J. Beyond crisis.

Verteilung des Aktionsstromes längs zwei Nerven Die vonN. Rashevsky entwickelten Formeln für die Verteilung des Aktionsstromes in einer unendlichen Nervenfaser werden auf den Fall von zwei in Serie aneinander anliegenden Fasern verallgemeinert.Distribution du Courant d'action lelong de deux nerfs en série La théorie mathématique développée parN. Rashevsky pour le cas d'un nerf d'extension indéfinie est généralisée pour le cas d'un nerf aboutissant à distance finie à un autre nerf.

Sedamdesetih godina dvadesetog veka Zil Delez, zajedno s Feliksom Gatarijem i Kler Parne, razvija koncepte uredjenja i dijagrama: barem do Hiljadu ravni uredjenje i dijagram - prekrsteni potom u stvarnu i apstraktnu masinu - sacinjavali su istureni teorijski temelj celokupnog Delezovog dela. Ideja dijagrama mnogo duguje Fukou iz doba Nadziranja i kaznjavanja, s kojim Delez u tim godinama, vodi neprekidni teorijski dijalog. Ona za njega predstavlja veliki ulog jer je trebalo misliti mutacije istorijskih struktura izvan vladajucih sema strukturalizma i marksizma. (...) Delez se, kao mislilac buduceg suprotstavlja Fukou, istoricaru-genealogicaru promena: u sredistu te rasprave oko dijagrama pojavljuju se dve razlicite koncepcije mutacije koje Delez nastoji da pomiri u svojoj knjizi o Fukou. (shrink)