Altruism is a well-studied phenomenon in the social sciences, but online altruism has received relatively little attention. In this article, we examine several cases of online altruism, and analyse the key characteristics of the phenomenon, in particular comparing and contrasting it against models of traditional donor behaviour. We suggest a novel definition of online altruism, and provide an in-depth, mixed-method study of a significant case, represented by the r/Assistance subreddit. We argue that online altruism can be characterized by its differing (...) experiences compared to traditional giving, from a giver’s point of view, and unique mechanisms and actions made possible by the internet. These findings explain why people give to anonymous strangers online and provide a new perspective on altruism that is important in building a more altruistic internet and society. (shrink)

This text is a critical review of Katherine Puddifoot's book, How Stereotypes Deceive Us (2021).

One of Martin Heidegger’s enduring philosophical legacies is his overall vision of what it is to be us. We—whoever that turns out to include—are cases of Dasein, and as such we are distinctively open to entities, including others and ourselves. In this essay, I paint a picture of that openness that aims to capture why Heidegger’s vision has so powerfully gripped so many. Drawing on Heidegger’s thought both early and late, I present a synoptic view of us as open to (...) the encounter with entities' bursting forth into presencing. We can be more or less closed off to this upsurge, but we can also allow it in its full power: in philosophical and poetic openness. I draw on Borgmann, Buber, Plato’s Socrates, Rilke, and others to capture our openness at its Heideggerian best—and we ourselves at our best, showing up radiantly for encounter. (shrink)

We defend in this essay Paul Ricœur’s hermeneutics of suspicion against Toril Moi’s debunking of it as a misguided interpretation of the practice of critical inquiry, and we relate the practice of a rigorous and critical empathy to the hermeneutics of suspicion. For Ricœur, empathy would not be a mere psychological mechanism by which one subject transiently identifies with another, but the ontological presence of the self with the Other as a way of being —listening as a human action that (...) is a fundamental way of being with the Other in which “hermeneutics can stand on the authority of the resources of past ontologies.” In a rational reconstruction of what a Ricœur-friendly approach to empathy would entail, a logical space can be made for empathy to avoid the epistemological paradoxes of Husserl and the ethical enthusiasms of Levinas. How this reconstruction of empathy would apply to empathic understanding, empathic responsiveness, empathic interpretation, and empathic receptivity is elaborated from a Ricœurian perspective. (shrink)

Social groups—like teams, committees, gender groups, and racial groups—play a central role in our lives and in philosophical inquiry. Here I develop and motivate a structuralist ontology of social groups centered on social structures (i.e., networks of relations that are constitutively dependent on social factors). The view delivers a picture that encompasses a diverse range of social groups, while maintaining important metaphysical and normative distinctions between groups of different kinds. It also meets the constraint that not every arbitrary collection of (...) people is a social group. In addition, the framework provides resources for developing a broader structuralist view in social ontology. (shrink)

Combining textual, visual, and ethnographic approaches to discourse, this article examines a variety of resources employed in the narrative construction of Washington, DC’s Chinatown in a billboard advertisement that de-ethnicizes the neighborhood. Analysis of the linguistic resources of narrative structure, comparative reference, and lexical cohesion reveals how the gentrification of Chinatown is constructed as a positive transformation driven by a corporation. Further, the visual juxtaposition of text with photos and graphics appropriates the community voice and infuses it with corporate identity. (...) This ideological multimodal construction of the transformation of Chinatown is finally actualized in its durable material form and strategic spatial emplacement. Incorporating ethnographic observation and an interview, this article illustrates how the symbolic power of narrative in place-making is interdependent on the economic power of its producer to propagate ideological discourse in the material world. (shrink)

How do things persist? Are material objects spread out through time just as they are spread out through space? Or is temporal persistence quite different from spatial extension? This key question lies at the heart of any metaphysical exploration of the material world, and it plays a crucial part in debates about personal identity and survival. This book explores and compares three theories of persistence — endurance, perdurance, and stage theories — investigating the ways in which they attempt to account (...) for the world around us. Having provided valuable clarification of its two main rivals, the book concludes by advocating stage theory. Such a basic issue about the nature of the physical world naturally has close ties with other central philosophical problems. This book includes discussions of change and parthood, of how we refer to material objects at different times, of the doctrine of Humean supervenience, and of the modal features of material things. In particular, it contains new accounts of the nature of worldly vagueness, and of what binds material things together over time, distinguishing the career of a natural object from an arbitrary sequence of events. Each chapter concludes with a reflection about the impact of these metaphysical debates upon questions about our personal identity and survival. (shrink)

Stereotypes sometimes lead us to make poor judgements of other people, but they also have the potential to facilitate quick, efficient, and accurate judgements. How can we discern whether any individual act of stereotyping will have the positive or negative effect? How Stereotypes Deceive Us addresses this question. It identifies various factors that determine whether or not the application of a stereotype to an individual in a specific context will facilitate or impede correct judgements and perceptions of the individual. It (...) challenges the thought that stereotyping only and always impedes correct judgement when the stereotypes that are applied are inaccurate, failing to reflect social realities. It argues instead that stereotypes that reflect social realities can lead to misperceptions and misjudgements, and that inaccurate but egalitarian social attitudes can therefore facilitate correct judgements and accurate perceptions. The arguments presented in this book have important implications for those who might engage in stereotyping and those who are at risk of being stereotyped. They have implications for those who work in healthcare and those who have mental health conditions. How Stereotypes Deceive Us provides a new conceptual framework-evaluative dispositionalism-that captures the epistemic faults of stereotypes and stereotyping, providing conceptual resources that can be used to improve our own thinking by avoiding the pitfalls of stereotyping, and to challenge other people's stereotyping where it is likely to lead to misperception and misjudgement. (shrink)

Social groups, including racial and gender groups and teams and committees, seem to play an important role in our world. This article examines key metaphysical questions regarding groups. I examine answers to the question ‘Do groups exist?’ I argue that worries about puzzles of composition, motivations to accept methodological individualism, and a rejection of Racialism support a negative answer to the question. An affirmative answer is supported by arguments that groups are efficacious, indispensible to our best theories, and accepted given (...) common sense. Then, I turn to an examination of the features of social groups. I argue that social groups can be divided into two sorts. Groups of Type 1 are organized social groups like courts and clubs. Groups of Type 2 are groups like Blacks, women, and lesbians. While groups of both sorts have some features in common, they also have marked differences in features. Finally, I turn to views of the nature of social groups. I argue that the difference in features provides evidence that social groups do not have a uniform nature. Teams and committees are structured wholes, while race and gender groups are social kinds. (shrink)

Although the principle of fair subject selection is a widely recognized requirement of ethical clinical research, it often yields conflicting imperatives, thus raising major ethical dilemmas regarding participant selection. In this paper, we diagnose the source of this problem, arguing that the principle of fair subject selection is best understood as a bundle of four distinct sub-principles, each with normative force and each yielding distinct imperatives: (1) fair inclusion; (2) fair burden sharing; (3) fair opportunity; and (4) fair distribution of (...) third-party risks. We first map out these distinct sub-principles, and then identify the ways in which they yield conflicting imperatives for the design of inclusion and exclusion criteria, and the recruitment of participants. We then offer guidance for how decision makers should navigate these conflicting imperatives to ensure that participants are selected fairly. (shrink)

In this paper I argue for a view of groups, things like teams, committees, clubs and courts. I begin by examining features all groups seem to share. I formulate a list of six features of groups that serve as criteria any adequate theory of groups must capture. Next, I examine four of the most prominent views of groups currently on offer—that groups are non-singular pluralities, fusions, aggregates and sets. I argue that each fails to capture one or more of the (...) criteria. Last, I develop a view of groups as realizations of structures. The view has two components. First, groups are entities with structure. Second, since groups are concreta, they exist only when a group structure is realized. A structure is realized when each of its functionally defined nodes or places are occupied. I show how such a view captures the six criteria for groups, which no other view of groups adequately does, while offering a substantive answer to the question, “What are groups?”. (shrink)

Highlighting main issues and controversies, this book brings together current philosophical discussions of symmetry in physics to provide an introduction to the subject for physicists and philosophers. The contributors cover all the fundamental symmetries of modern physics, such as CPT and permutation symmetry, as well as discussing symmetry-breaking and general interpretational issues. Classic texts are followed by new review articles and shorter commentaries for each topic. Suitable for courses on the foundations of physics, philosophy of physics and philosophy of science, (...) the volume is a valuable reference for students and researchers. (shrink)

Let T be a complete o-minimal extension of the theory of real closed fields. We characterize the convex hulls of elementary substructures of models of T and show that the residue field of such a convex hull has a natural expansion to a model of T. We give a quantifier elimination relative to T for the theory of pairs (R, V) where $\mathscr{R} \models T$ and V ≠ R is the convex hull of an elementary substructure of R. We deduce (...) that the theory of such pairs is complete and weakly o-minimal. We also give a quantifier elimination relative to T for the theory of pairs (R, N) with R a model of T and N a proper elementary substructure that is Dedekind complete in R. We deduce that the theory of such "tame" pairs is complete. (shrink)

This article takes Heidegger's design distinctions for human being [Dasein] including affectivity, understanding, and speech, and, using these distinctions, generates a Heideggerian definition of empathy [Einfuehlung]. This article distinguishes empathic receptivity, empathic understanding, empathic interpretation, and empathic speech (or responsiveness). It also looks at characteristic breakdowns.

The distinction between “empathy” and “sympathy” in the context of ethics is a dynamic and challenging one. The eighteenth century texts of David Hume and Adam Smith used the word "sympathy," but not "empathy," although the conceptual distinction marked by empathy was doing essential work in their writings. After discussing the early uses of these terms, this article is organized historically. Two traditions are distinguished. The first is the Anglo-American tradition, and it extends from Hume and Smith to the twenty-first (...) century work of Michael Slote. Stephen Darwall’s contribution is applied in engaging Hume and Smith. Finally, the interrelation of empathy, sympathy and altruism is explored in the work of John Rawls and Thomas Nagel. The second tradition is the Continental one. It extends from the spirituality of Johann Herder to the phenomenological movement of Edmund Husserl, Martin Heidegger, Max Scheler, and Edith Stein. The intentional analysis of empathy is directly relevant to the constitution of the social community in a broad, normative relationship with the "Other.". (shrink)

Symmetry considerations dominate modern fundamental physics, both in quantum theory and in relativity. Philosophers are now beginning to devote increasing attention to such issues as the significance of gauge symmetry, quantum particle identity in the light of permutation symmetry, how to make sense of parity violation, the role of symmetry breaking, the empirical status of symmetry principles, and so forth. These issues relate directly to traditional problems in the philosophy of science, including the status of the laws of nature, the (...) relationships between mathematics, physical theory, and the world, and the extent to which mathematics suggests new physics.This entry begins with a brief description of the historical roots and emergence of the concept of symmetry that is at work in modern science. It then turns to the application of this concept to physics, distinguishing between two different uses of symmetry: symmetry principles versus symmetry arguments. It mentions the different varieties of physical symmetries, outlining the ways in which they were introduced into physics. Then, stepping back from the details of the various symmetries, it makes some remarks of a general nature concerning the status and significance of symmetries in physics. (shrink)

Recently several philosophers have argued that racial, gender, and other social generic generalizations should be avoided given their propensity to promote essentialist thinking, obscure the social nature of categories, and contribute to oppression. Here I argue that a general prohibition against social generics goes too far. Given that the truth of many generics require regularities or systematic rather than mere accidental correlations, they are our best means for describing structural forms of violence and discrimination. Moreover, their accuracy, their persistence in (...) the face of counterexamples, and features of the contemporary socio-political context make generics useful linguistic tools in social justice projects. (shrink)

This work presents a conception of Hume's overall philosophical stance which is derived from a focus on his Dialogues Concerning Natural Religion and The Natural History of Religion. A broad context is provided by frequent references to A Treatise of Human Nature and to An Enquiry Concerning Human Understanding as well as to other relevant essays and letters written by Hume. Religious Naturalism is a complex tapestry woven of aesthetic, ethical, epistemological and metaphysical elements. The religious element in Hume's writings, (...) which some commentators see as a transcendent position, is interpreted as an immanentist religiosity akin to that of Spinoza and Einstein. Hume's three "strong natural beliefs" in "self", objects and causality, come together as a metaphysical faith in the ultimate reality of a shared cosmos. Hume's aesthetic response is expressed as a sense of the sublimity of the cosmos even in the midst of skeptical doubt. In Hume's religious naturalism his epistemological skepticism casts doubt on and tempers his metaphysical faith. It is shown that Hume's overriding ethical concern was to further the happiness of humanity by replacing the "pernicious superstition" of supernaturalism with an immanentist position which affirms the inexplicable presence of an eternal cosmos. This position is what is here termed Religious Naturalism. (shrink)

I solve here some problems left open in “T-convexity and Tame Extensions” [9]. Familiarity with [9] is assumed, and I will freely use its notations. In particular,Twill denote a completeo-minimal theory extending RCF, the theory of real closed fields. Let (,V) ⊨Tconvex, let=V/m(V)be the residue field, with residue class mapx↦:V↦, and let υ:→ Γ be the associated valuation. “Definable” will mean “definable with parameters”.The main goal of this article is to determine the structure induced by(,V)on its residue fieldand on its (...) value group Γ. In [9] we expanded the ordered fieldto a model ofTas follows. Take a tame elementary substructure′ ofsuch thatR′ ⊆VandR′maps bijectively ontounder the residue class map, and make this bijection into an isomorphism′ ≌ofT-models. (We showed such′ exists, and that this gives an expansion ofto aT-model that is independent of the choice of′.). (shrink)

It has been argued that humans can face an ethical/epistemic dilemma over the automatic stereotyping involved in implicit bias: ethical demands require that we consistently treat people equally, as equally likely to possess certain traits, but if our aim is knowledge or understanding our responses should reflect social inequalities meaning that members of certain social groups are statistically more likely than others to possess particular features. I use psychological research to argue that often the best choice from the epistemic perspective (...) is the same as the best choice from the ethical perspective: to avoid automatic stereotyping even when this involves failing to reflect social realities in our judgements. This argument has an important implication: it shows that it is not possible to successfully defend an act of automatic stereotyping simply on the basis that the stereotype reflects an aspect of social reality. An act of automatic stereotyping can be poor from an epistemic perspective even if the stereotype that is activated reflects reality. (shrink)

Some language encourages essentialist thinking. While philosophers have largely focused on generics and essentialism, I argue that nouns as a category are poised to refer to kinds and to promote representational essentializing. Our psychological propensity to essentialize when nouns are used reveals a limitation for anti-essentialist ameliorative projects. Even ameliorated nouns can continue to underpin essentialist thinking. I conclude by arguing that representational essentialism does not doom anti-essentialist ameliorative projects. Rather it reveals that would-be ameliorators ought to attend to the (...) propensities for our representational devices to essentialize and to the complex relationship between essentialism and prejudice. (shrink)

This study examines public health nurses’ perceptions and concerns about the implications of Japan’s new long-term care insurance law concerning care provision for elderly people and their families. Respondents voiced their primary concern about this law as access to services for all elderly people needing care, and defined their major responsibility as strengthening health promotion and illness prevention programmes. Although wanting to expand their roles to meet the health care, social and public policy advocacy needs of elderly persons and their (...) families, respondents also stated their concern for the possible lack of enough resources for this expansion to support family caregivers adequately. They viewed their first function as developing collaborative relationships with local government officials to help to assure sufficient resources to provide the necessary foundation for long-term care programmes to deliver services to all those in need. These concerns fall within the larger ethical issue of distributive justice in a society based on the obligations of the state to citizens and the family to its members, especially elderly relatives, who, according to traditional Japanese values, retain respect. (shrink)

Research with Children is a unique resource book on the methodology of childhood research. Leading and new researchers within the social studies of childhood discuss central questions of epistemology and methodology, demonstrating the links between theory and practice. The theoretical and practical questions are set out in a clear and well-argued fashion and will therefore appeal both to the newcomer to childhood studies and to experienced researchers in the field.

Findings from the cognitive sciences suggest that the cognitive mechanisms responsible for some memory errors are adaptive, bringing benefits to the organism. In this paper we argue that the same cognitive mechanisms also bring a suite of significant epistemic benefits, increasing the chance of an agent obtaining epistemic goods like true belief and knowledge. This result provides a significant challenge to the folk conception of memory beliefs that are false, according to which they are a sign of cognitive frailty, indicating (...) that a person is less reliable than others or their former self. Evidence of memory errors can undermine a person’s view of themselves as a competent epistemic agent, but we show that false memory beliefs can be the result of the ordinary operation of cognitive mechanisms found across the species, which bring substantial epistemic benefits. This challenge to the folk conception is not adequately captured by existing epistemological theories. However, it can be captured by the notion of epistemic innocence, which has previously been deployed to highlight how beliefs which have epistemic costs can also bring significant epistemic benefits. We therefore argue that the notion of epistemic innocence should be expanded so that it applies not just to beliefs but also to cognitive mechanisms. (shrink)

"My plan in this book," writes Father Danielou, the eminent French theologian, "is not to record what I say of God, but what God has said of Himselfà to place religions and philosophies, the Old Testament and the New, theology and mysticism, in their proper relationship with the knowledge of God." God and the Ways of Knowing is a classic work of theology and spirituality that presents a subtle and penetrating interpretation of the ways by which man comes to the (...) knowledge of Godùeach form of knowledge carrying him both higher and deeper. (shrink)

Comme un arbre refleurit, tout renouveau intellectuel ou spirituel puise sa sève dans les racines de son passé. C'est ce dont témoigne cet essai publié en 1957, à la veille du concile Vatican II. Philon est, en effet, un juif imprégné de philosophie grecque, bon représentant du milieu culturel si riche de la ville d'Alexandrie, au tournant de notre ère. Contemporain du Christ sans l'avoir connu, il appartient à un judaïsme très ouvert qui a déjà traduit la Bible en grec (...) deux siècles auparavant. Il a profondément influencé la littérature chrétienne des premiers siècles et reste un exemple et un espoir de rencontre entre ces deux cultures et ces deux religions. Nul plus que Jean Daniélou, lui-même si cultivé et si ouvert, ne pouvait mieux faire revivre cette personnalité attachante et exceptionnelle. (shrink)

Life of Philo -- Philo and his time -- The Bible at Alexandria -- Philo's exegesis -- Philo's theology -- Philo's spirituality -- Philo and the New Testament.

Symmetry, intended as invariance with respect to a transformation (more precisely, with respect to a transformation group), has acquired more and more importance in modern physics. This Chapter explores in 8 Sections the meaning, application and interpretation of symmetry in classical physics. This is done both in general, and with attention to specific topics. The general topics include illustration of the distinctions between symmetries of objects and of laws, and between symmetry principles and symmetry arguments (such as Curie's principle), and (...) reviewing the meaning and various types of symmetry that may be found in classical physics, along with different interpretative strategies that may be adopted. Specific topics discussed include the historical path by which group theory entered classical physics, transformation theory in classical mechanics, the relativity principle in Einstein's Special Theory of Relativity, general covariance in his General Theory of Relativity, and Noether's theorems. In bringing these diverse materials together in a single Chapter, we display the pervasive and powerful influence of symmetry in classical physics, and offer a possible framework for the further philosophical investigation of this topic. (shrink)

Slurs are expressions that can be used to demean and dehumanize targets based on their membership in racial, ethnic, religious, gender, or sexual orientation groups. Almost all treatments of slurs posit that they have derogatory content of some sort. Such views—which I call content-based—must explain why in cases of appropriation slurs fail to express their standard derogatory contents. A popular strategy is to take appropriated slurs to be ambiguous; they have both a derogatory content and a positive appropriated content. However, (...) if appropriated slurs are ambiguous, why can only members in the target group use them to express a non-offensive/positive meaning? Here, I develop and motivate an answer that could be adopted by any content-based theorist. I argue that appropriated contents of slurs include a plural fi rst-person pronoun. I show how the semantics of pronouns like ‘we’ can be put to use to explain why only some can use a slur to express its appropriated content. Moreover, I argue that the picture I develop is motivated by the process of appropriation and helps to explain how it achieves its aims of promoting group solidarity and positive group identity. (shrink)

This book has two main and connected themes - the conception and articulation of time in the Greek world and the creation of history, especially in the context of the Greek city. Both how time is expressed and how the past is presented have often been seen as reflections of society. By looking at the construction of the past through the medium of local historiography, where we can view these issues in the relatively restricted world of individual city-states, we can (...) gain a clearer insight into how different versions of the past and different constructions of time were offered to the community for approval. In this way, the citizens were able to negotiate time past and indeed their own history, and thereby to express their values and aspirations. (shrink)

Katherine Clarke explores three authors who wrote about the rise of the Roman Empire - Polybius, Posidonius, and Strabo. She examines the overlap between geography and history in their work, and considers how pre-existing traditions were used but transformed in order to describe the new world of Rome.

Predicate nominals (e.g., “is a female”) seem to label or categorize their subjects, while their adjectival correlates (e.g., “is female”) merely attribute a property. Predicate nominals also elicit essentializing inferential judgments about inductive potential and stable explanatory membership. Data from psychology and semantics support that this distinction is robust and productive. I argue that while the difference between predicate nominals and predicate adjectives is elided by standard semantic theories, it ought not be. I then develop and defend a psychologically motivated (...) semantic account on which predicate nominals attribute kind membership and trigger a presupposition that underpins our essentialist judgments. (shrink)

This article theorises the process of adapting my research on intercultural communication for public performance in collaboration with a theatre company. I frame the collaboration as taking place within a hospitable institutional space, and then consider what it means to enact hospitality interpersonally, given Derrida's understanding that the condition of its possibility is at the same time the condition of its impossibility. I suggest that the enactment of hospitality can be understood through the application of an intercultural theoretical framework based (...) on Mikhail Bakhtin's concept of outsideness, and that this framework can be applied to both the collaboration with the theatre company and to the purposes of public engagement with research. I conclude with a consideration of the relationship between hospitality and hope, and a call to move towards a ‘condition of possibility’ for working as academics, for public engagement, and for living. (shrink)

This paper explores violence in intimate relationships in one low-income community in the Western Cape, South Africa. In this community most intimate relationships (including parentchild, intimate partner relationships and friendships) seem to be characterized by anger, rage and also violence. In our analysis we discuss how the concepts of shame, guilt and the compulsion to repeat can serve to illuminate the seemingly inevitable link between violence and care in this specific community. It also seems that contextual factors such as class, (...) gender and race shape not only the form violence assumes, but also to whom it is directed. While we pay attention to the material and ideological conditions that shape the lives of individual storytellers, we also focus on the ways in which violence is represented in the individual stories. (shrink)

Technology acceptance by users has been extensively studied in recent years in various fields such as technologies for learning, e-commerce, and business technologies. This review focuses specifically on Human Resource Information Systems and its acceptance by users. Given their widespread use in organisations, HRIS acceptance has been researched but not synthesised in any way. This article aims to review the effectiveness of the classical TAM and UTAUT models commonly used for new technologies and to identify the variables added to these (...) models to better predict HRIS acceptance by employees. It also highlights the importance of the human-machine-organisation relationship to contribute to the understanding of HRIS acceptance in professional environments. This review confirms the effectiveness of the TAM and UTAUT models and proposes to develop them by variables reffering to technological characteristics, user satisfaction with the system, and organisational variables. The discussion focuses on the retroaction possibilities between the different Human-Machine-Organisation relation levels. (shrink)

Perceptual grouping has traditionally been thought to be governed by innate, universal principles. However, recent work has found differences in Japanese and English speakers' non-linguistic perceptual grouping, implicating language in non-linguistic perceptual processes (Iversen, Patel, & Ohgushi, 2008). Two experiments test Japanese- and English-learning infants of 5-6 and 7-8 months of age to explore the development of grouping preferences. At 5-6 months, neither the Japanese nor the English infants revealed any systematic perceptual biases. However, by 7-8 months, the same age (...) as when linguistic phrasal grouping develops, infants developed non-linguistic grouping preferences consistent with their language's structure (and the grouping biases found in adulthood). These results reveal an early difference in non-linguistic perception between infants growing up in different language environments. The possibility that infants' linguistic phrasal grouping is bootstrapped by abstract perceptual principles is discussed. (shrink)

In ‘Utility of Religion’, Mill argues that a wholly naturalistic religion of humanity would promote individual and social welfare better than supernatural religions like Christianity; in ‘Theism’, however, Mill defends the salutary effects of hope in an afterlife. While commentators have acknowledged this discrepancy, they have not examined the utilitarian value of what Mill terms ‘illusions’. In this essay, I explain Mill's case against the utility of supernatural religious belief and then argue that Mill cannot dismiss the utility of hope (...) in an ultimate justice since it need not pervert the intellect or morality. There are thus utilitarian grounds to support some supernatural illusions, which undermines Mill's defence of an exclusively naturalistic religion. I conclude with the suggestion that while the utility of religious belief leads Mill toward William James's view, they disagree about whether supernatural religious sentiment has any unique, intrinsic force. (shrink)

Cancer is generally defined as uncontrollable growth of cells caused by genetic aberrations and/or environmental factors. Yet contagious cancers also occur. The recent emergence of a contagious cancer in Tasmanian devils has reignited interest in transmissible cancers. Two naturally occurring transmissible cancers are known: devil facial tumour disease and canine transmissible venereal tumour. Both cancers evolved once and have then been transmitted from one individual to another as clonal cell lines. The dog cancer is ancient; having evolved more than 6,000 (...) years ago, while the devil disease was first seen in 1996. In this review I will compare and contrast the two diseases focusing on the life histories of the clonal cell lines, their evolutionary trajectories and the mechanisms by which they have achieved immune tolerance. A greater understanding of these contagious cancers will provide unique insights into the role of the immune system in shaping tumour evolution and may uncover novel approaches for treating human cancer. (shrink)