Our objectives in this article are to bring some theoretical order into developmental sequences and simultaneities in children’s ability to appreciate multiple labels for single objects, to reason with identity statements, to reason hypothetically, counterfactually, and with beliefs and desires, and to explain why an ‘implicit’ understanding of belief occurs before an ‘explicit’ understanding. The central idea behind our explanation is the emerging grasp of how objects of thought and desire relate to real objects and to each other. To capture (...) this idea we make use of the notion of discourse referents, as did Perner and Brandl (2005), to explain the developmental link between understanding beliefs and alternative naming. We present confirming evidence of the prediction from this analysis that children should have comparable problems with understanding identity statements. We explain the precociously correct answers in ‘implicit’ false belief tests based on indirect measures in the following way: From infancy children are able to keep track of other people’s experiences, to reason about counterfactual circumstances, and to reason about goal-directed (rational) action depending on given circumstances. Indirect tasks reduce the bias to use actual circumstances for reasoning about goal directed action compared to the traditional task, which leads to more correct answers. An emerging metarepresentational understanding helps overcome these biases and enables not only correct action prediction but also the explanation of erroneous actions. The common metarepresentational element explains why false belief tasks and the alternative naming task are mastered at the same time as children understand identity statements. (shrink)

We argue that episodic remembering, understood as the ability to re-experience past events, requires a particular kind of introspective ability and understanding. It requires the understanding that first person experiences can represent actual events. In this respect it differs from the understanding required by the traditional false belief test for children, where a third person attribution (to others or self) of a behavior governing representation is sufficient. The understanding of first person experiences as representations is also required for problem solving (...) with images. In support of this argument we review developmental evidence that children's episodic remembering is independent of and emerges after mastery of the false belief task but emerges together with the use of imagery for solving visual rotation tasks. (shrink)

We argue for teleology as a description of the way in which we ordinarily understand others’ intentional actions. Teleology starts from the close resemblance between the reasoning involved in understanding others’ actions and one’s own practical reasoning involved in deciding what to do. We carve out teleology’s distinctive features more sharply by comparing it to its three main competitors: theory theory, simulation theory, and rationality theory. The plausibility of teleology as our way of understanding others is underlined by developmental data (...) in its favour. (shrink)

In most developmental studies the only error children could make on counterfactual tasks was to answer with the current state of affairs. It was concluded that children who did not show this error are able to reason counterfactually. However, children might have avoided this error by using basic conditional reasoning (Rafetseder, Cristi-Vargas, & Perner, 2010). Basic conditional reasoning takes background assumptions represented as conditionals about how the world works. If an antecedent of one of these conditionals is provided by the (...) task, then a likely conclusion can be inferred based only on background assumptions. A critical feature of counterfactual reasoning is that the selection of these additional assumptions is constrained by actual events to which the counterfactual is taken to be counterfactual. In contrast, in basic conditional reasoning one enriches the given antecedent with any plausible assumptions, unconstrained by actual events. In our tasks basic conditional reasoning leads to different answers from counterfactual reasoning. For instance, a doctor, sitting in the park with the intention of reading a paper, is called to an emergency at the swimming pool. The question, “If there had been no emergency, where would the doctor be?” should counterfactually be answered “in the park”. But by ignoring the doctor's intentions, and just reasoning from premises about the default location of a hospital doctor who has not been called out to an emergency, one might answer: “in the hospital”. Only by 6 years of age did children mostly give correct answers. (shrink)

A method is presented for deciding whether correct predictions about other people are based on simulation or theory use. The differentiating power of this method was assessed with cognitive estimation biases (e.g. estimating the area of Brazil) in two variations. Experiments 1 and 2 operated with the influence of response scales of different length. Experiment 3 used the difference between free estimates that tended to be far off the true value and estimates constrained by an appropriate response scale, where estimates (...) became greatly more realistic. The critical question is how well observer subjects can predict these target biases under two different presentation conditions. Response scale biases (Experiments 1 and 2) were more strongly predicted when observer subjects were presented with the two scales juxtaposed, than when responses for each scale were given independently. This speaks for the use of a theory, since simulation should, if there is any difference at all, be made more difficult by the juxtaposition of conditions. The difference between free and constrained estimations (Experiment 3) was more strongly predicted under independent than under juxtaposed presentation. This speaks for the use of simulation since use of a theory should, if anything, be helped by juxtaposition of problems since it helps highlight the theoretically relevant factor. Results are discussed in view of recent proposals about when simulation is likely to be used, i.e. for belief fixation but not action prediction (Stich and Nichols, 1995b), for content fixation (Heal, 1996a), and for rational effects only (Heal, 1996b). (shrink)

We develop a new theory of the cognitive changes around 4 years of age by trying to explain why understanding of false belief and of alternative naming emerge at this age. We make use of the notion of discourse referents as it is used in File Change Semantics, one of the early forms of the more widely known Discourse Representation Theory. The assumed cognitive change exists in how children can link DRs in their mind to external referents. The younger children (...) check whether the conditions for a DR match the conditions of an external entity. The older children, in addition, have an explicit understanding of reference in virtue of making explicit identity assertions. This involves the metarepresentational ability of representing that different DRs represent the same external referent, which — we argue — is required for alternative naming and for the false belief task. (shrink)

In this project, a spiral fast imaging sequence was implemented on a Bruker Avance MR system. Acquisition and processing schemes were developed to measure the experimental k-space trajectories. Since errors in k-space are reflected as errors in the corresponding image, we used different strategies to measure and calculate corrections for deviation of the experimental k-space trajectory from the theoretical one. Even if the k-space trajectories deviate from the theoretical ones, an experimentally measured trajectory can be incorporated in the spiral reconstruction (...) and a reduction of image artifacts can be obtained. (shrink)

This article wants to answer three questions: first, why is not only sensibility but visibility important for modern democracy? Second, why is art or aesthetic experience important for both democracy and visibility? And third, how is it possible that aesthetic experience generates effects that conduce to democracy? Answering these questions aims at highlighting an inner connection between democracy, feelings and aesthetics. For a democratic community, on the one hand, cannot exclude feelings from political discourse, but, on the other hand, cannot (...) accept them in their immediate and absolute form. Feelings need ‘transformation’, and the best popular medium for this is aesthetic experience. (shrink)

Millikan's externalist account of concept acquisition cannot completely avoid the distinction between central (defining) and peripheral (characteristic) features, because some knowledge is required to achieve reference and to decide what kind of information to record about the identified substances. However, the emphasis on external reference may provide the requisite principled way to make this distinction.

Cílem studie je srovnání Platónova a Aristotelova výkladu vlastností těžké a lehké. Nejprve jsou představeny hlavní motivy obou výkladů a poté následuje srovnání z hlediska využití empirických dat, z hlediska jejich explikační síly a také co do blízkosti modernímu pojetí tíže. V závěru se ukazuje, že Aristotelova koncepce těžkého a lehkého je propracovanější a komplexnější, ovšem mnohem stručnější výklad Platónův má také značné explikační možnosti a v určitých ohledech Aristotelovu teorii předčí.

Cílem studie je srovnání Platónova a Aristotelova výkladu vlastností těžké a lehké. Nejprve jsou představeny hlavní motivy obou výkladů a poté následuje srovnání z hlediska využití empirických dat, z hlediska jejich explikační síly a také co do blízkosti modernímu pojetí tíže. V závěru se ukazuje, že Aristotelova koncepce těžkého a lehkého je propracovanější a komplexnější, ovšem mnohem stručnější výklad Platónův má také značné explikační možnosti a v určitých ohledech Aristotelovu teorii předčí.

Calcium plays an important role in regulating a great variety of neuronal processes, and many efforts are made to generate gadolinium complexes that can act as calcium-dependent MRI contrast agents. A series of gadolinium chelate complexes based on DO3A were developed, bearing phosphonate groups as an additional coordination sites, which is hypothesized to change relaxivity in magnetic resonance experiments dynamically with Ca2+ concentration. Different lengths of the phosphonate side chains are expected to lead to different binding constants of the phosphonate (...) - gadolinium bonds. The latter property can be exploited for fine-tuning the sensitivity of the agent to calcium ion concentration. (shrink)

The ability of non-invasively observing changes in the Ca2+ concentrations is important in the understanding of a great variety of neuronal processes. Several compounds were designed (Fig.1) to take advantage of the different binding abilities of carboxylates and phosphonates to gadolinium. Furthermore the different affinities of the two functional groups to Ca2+ permit to obtain free coordination sites at gadolinium. The generation of these coordination sites, which are mandatory for water relaxivity, depends on the structure of the complexes and the (...) Ca2+ concentration. Gadolinium complexes 1 and 2 were synthesized and relaxivity studies were performed. (shrink)

Functionally distinct anatomic subdivisions of the brain can often be only a few millimeters in one or more dimensions. The study of metabolic differences in such structures by means of localized in vivo MR spectroscopy is therefore challenging, if not impossible. In fact, the spatial resolution of chemical shift imaging (CSI) in humans is typically in the range of centimeters. The aim of the present study was to optimize 1H CSI in monkeys and demonstrate the feasibility of high spatial resolutions (...) up to 1.4 ؋ 2 ؋ 1.4 mm3. The obtained spatial resolution permitted the segregation of gray and white matter in the visual cortex based on the concentration of different metabolites and neurotrans- mitters like N-acetylaspartate, glutamate, and creatine. Con- centration ratios of white matter versus gray matter tissue as well as between metabolites matched those reported in the literature from healthy human brain, demonstrating the consis- tency and reliability of the procedure. Magn Reson Med 54: 1541–1546, 2005. © 2005 Wiley-Liss, Inc. Key words: in vivo 1H NMR spectroscopy; spectroscopic imag- ing; chemical shift imaging; spatial resolution; monkey visual cortex.. (shrink)

This is a work by Josef Pieper, one of this century's most profound and lucid expositors of the thought of St. Thomas Aquinas.

"During the last months of the war, Josef Pieper saw the realization of a long-cherished plan to escape from the "lethal chaos" that was the Germany of that time, "plucked," he writes, "as was Habakkuk, by the hair of his head... to be planted into a realm of the most peaceful seclusion, whose borders and exists were, of course, controlled by armed sentries." There he made contact with a friend close-by, who possessed an amazing library, and Pieper hit upon (...) the idea of reading the letters of Goethe from that library. Soon, however, he decided to read the entire Weimar edition of fifty volumes, which were brought to him in sequence, two or three at a time." "It was precisely in the seclusion, the limitation, the silence of Goethe that made the strongest impact on Pieper. Here was modern Germany's quintessential conversationalist intellectual, but the strength of his words came from the restraint behind them, even to the point of purposeful forgetting." --Book Jacket. (shrink)