College underachievers’ educational transformation is the important work to comprehensively cultivate the builders and successors of the socialism with Chinese characteristics, but a hard, sensitive, and complex work. Starting from the root of this problem, this article puts forward the “people-oriented” educational concept and research method, explores the work art of underachievers’ educational transformation, in order to comprehensively enhance the effect of educational transformation.

v. 1-32. Mou Zongsan xian sheng quan ji -- [33] Mou Zongsan xian sheng quan ji. Zong xu xiang mu.

Despite its widespread existence, the adaptive role of aneuploidy (the abnormal state of having an unequal number of different chromosomes) has been a subject of debate. Cellular aneuploidy has been associated with enhanced resistance to stress, whereas on the organismal level it is detrimental to multicellular species. Certain aneuploid karyotypes are deleterious for specific environments, but karyotype diversity in a population potentiates adaptive evolution. To reconcile these paradoxical observations, this review distinguishes the role of aneuploidy in cellular versus organismal evolution. (...) Further, it proposes a population genetics perspective to examine the behavior of aneuploidy on a populational versus individual level. By altering the copy number of a significant portion of the genome, aneuploidy introduces large phenotypic leaps that enable small cell populations to explore a wide phenotypic landscape, from which adaptive traits can be selected. The production of chromosome number variation can be further increased by stress‐ or mutation‐induced chromosomal instability, fueling rapid cellular adaptation. (shrink)

本书收录了作者讲授宋明儒学、反映学者思想发展的讲辞文本形式,以及对于明代名儒刘蕺山的学术及刘氏区分“心宗”与“性宗”进行研究的文章等。.

In this paper, I give a metaphilosophical analysis of the core idea of deflationism by discussing some basic conceptual and methodological issues involved in the debate between deflationism and substantivism. In so doing, I argue for three positive points. First, the crux of the dispute between deflationism and substantivism is whether or not truth is substantive in its metaphysical nature and in its explanatory role in philosophical enterprises, rather than whether or not a minimal approach regarding conceptual resources is taken (...) to explain truth; a minimal approach itself is philosophically innocent. Second, there is no intrinsic connection between the core idea of deflationism and the Tarski-style equivalence thesis, which is often identified as implying or supporting the former. Third, there are some unbridged fundamental gaps between the core idea of deflationism and various redundancy theses; these redundancy theses cannot be identified as the former, nor can they be used to justify the former on their own. (shrink)

A concise alphabetic guide to the main concepts, figures, topics and important movements of thought that have shaped Chinese philosophy over the last three thousand years. The entries are concisely written, terms are cross-referenced and transcriptions are typically given in the pinyin system while the Chinese originals for important concepts are also provided. Chinese Philosophy A-Z stresses philosophical relevance in choosing entries while paying due attention to historical links between relevant ideas and movements of thought. The volume also shows how (...) some of the central ideas under discussion contribute to the philosophical enterprise as a whole. The book is aimed at students, teachers of philosophy, and educated non-specialists who are interested in Chinese philosophy, particularly those readers new to Chinese philosophy. (shrink)

本书包括周敦颐的“太极图”,张载“气”的哲学,王安石的“新学”思想,二程的理学思想,朱熹的理本体论哲学,陆九渊的“心学”,陈亮“道在物中”的思想等内容。.

The History of Chinese Philosophy is a comprehensive and authoritative examination of the movements and thinkers that have shaped Chinese philosophy over the last three thousand years. An outstanding team of international contributors provide seventeen accessible entries organised into five clear parts: Identity of Chinese Philosophy Classical Chinese Philosophy : Pre-Han Period Classical Chinese Philosophy : From Han Through Tang Classical Chinese Philosophy : From Song Through Early Qing Modern Chinese Philosophy: From Late Qing Through 21st Century This outstanding collection (...) is essential reading for students of Chinese philosophy, and will be of interest to those seeking to explore the lasting significance this rich and complex philosophical tradition. (shrink)

The Hippo pathway, a cascade of protein kinases that inhibits the oncogenic transcriptional coactivators YAP and TAZ, was discovered in Drosophila as a major determinant of organ size in development. Known modes of regulation involve surface proteins that mediate cell‐cell contact or determine epithelial cell polarity which, in a tissue‐specific manner, use intracellular complexes containing FERM domain and actin‐binding proteins to modulate the kinase activities or directly sequester YAP. Unexpectedly, recent work demonstrates that GPCRs, especially those signaling through Galpha12/13 such (...) as the protease activated receptor PAR1, cause potent YAP dephosphorylation and activation. This response requires active RhoA GTPase and increased assembly of filamentous (F‐)actin. Morever, cell architectures that promote F‐actin assembly per se also activate YAP by kinase‐dependent and independent mechanisms. These findings unveil the ability of GPCRs to activate the YAP oncogene through a newly recognized signaling function of the actin cytoskeleton, likely to be especially important for normal and cancerous stem cells. (shrink)

There is a substantial shortage of organs available for transplantation in Bangladesh. This has resulted in the commodification of organs. This study analyzes the religious, cultural, and legal barriers to organ donation in Bangladesh. It is based on the examination of available literature and primary sources i.e. religious decrees and opinions of religious leaders of faith traditions, and the Bangladesh Organ Donation Act, 1999. The literature was retrieved from databases, such as PubMed, BioMed, and Google Scholar using the key words: (...) organ donation in Islam, organ donation in Bangladesh, organ donation and religions. The study found that although many Islamic scholars accept organ donation, both living and cadaveric, under some conditions, some Bangladeshi Muslim clerics oppose donation. They argue that organ retrieval violates the sanctity of the human body and retrieval of organs may harm a living donor or lead to death, and organ donation may encourage the commercialization of body parts. Both commercialization and harming oneself are considered sins. Thus, the divergent views of Muslim clerics are a major barrier to organ donation among the Bangladeshi Muslims. Cultural and social factors also have a negative impact. Most people desire to be buried with their bodies intact. Although the Bangladesh government promulgated the Bangladesh Organ Donation Act, 1999, and amended it in 2018, it restricted donors and recipients to members of the extended family, which also reduced the donor pool. This study argues that the Muslim Orthodox clerics’ stand against organ donation and other cultural and legal issues are the major obstacles to organ donation in Bangladesh. (shrink)

Post-stroke depression is a serious complication of stroke that significantly restricts rehabilitation. The use of immersive virtual reality for stroke survivors is promising. Herein, we investigated the effects of a novel immersive virtual reality training system on PSD and explored induced effective connectivity alterations in emotional networks using multivariate Granger causality analysis. Forty-four patients with PSD were equally allocated into an immersive-virtual reality group and a control group. In addition to their usual rehabilitation treatments, the participants in the immersive-virtual reality (...) group participated in an immersive-virtual reality rehabilitation program, while the patients in the control group received 2D virtual reality rehabilitation training. The Hamilton Depression Rating Scale, modified Barthel Index, and resting-state functional magnetic resonance imaging data were collected before and after a 4-week intervention. rsfMRI data were analyzed using multivariate GCA. We found that the immersive virtual reality training was more effective in improving depression in patients with PSD but had no statistically significant improvement in MBI scores compared to the control group. The GCA showed that the following causal connectivities were strengthened after immersive virtual reality training: from the amygdala, insula, middle temporal gyrus, and caudate nucleus to the dorsolateral prefrontal cortex; from the insula to the medial prefrontal cortex; and from the thalamus to the posterior superior temporal sulcus. These causal connectivities were weakened after treatment in the control group. Our results indicated the neurotherapeutic use of immersive virtual reality rehabilitation as an effective non-pharmacological intervention for PSD; the alteration of causal connectivity in emotional networks might constitute the neural mechanisms underlying immersive-virtual reality rehabilitation in PSD. (shrink)

In this journal theme introduction, first, I explain how comparative philosophy as explored in the journal Comparative Philosophy is understood and how it is intrinsically related to the constructive engagement strategy. Second, to characterize more clearly and accurately some related methodological points of the constructive-engagement strategy, and also to explain how constructive engagement is possible, I introduce some needed conceptual and explanatory resources and a meta-methodological framework and endeavor to identify adequacy conditions for methodological guiding principles in comparative studies. Third, (...) as a case analysis, I show how the constructive-engagement reflective practice bears on recent studies of Chinese and comparative Chinese-Western philosophy, especially in the past decade, for two purposes: to illustrate the foregoing theoretic characterization of the constructive engagement strategy, and to identify and explain some constructive morals that might have general significance for comparative studies. (shrink)

From the modern point of view, the Daoist regimen culture in China is actually a kind of oriental bionomy. Although it is less developed than the Western life sciences in terms of details and techniques, it has unique advantages in terms of its comprehensive grasp and dynamic observation of life, as well as its emphasis on the development of life potentiality and on the self adjustment and improvement of living bodies. Chen Yingning reestablished a Daoist bionomy through Xianxue 仙学 (Philosophy (...) of Immortals) which involves religious faith, philosophy and sciences, leaving us a valuable legacy. To establish a new bionomy system required by the modern society through learning from the Daoist bionomy, the academic circle has to seriously explore the four issues: (1) at the level of faith, to turn the Daoist faith in deities and gods into a pursuit of ideal personality; (2) with respect to the principles of regimen, to extend the dual cultivation into a kind of universal concept; (3) as with the way of regimen, to learn from the regimen thought of Daoism and combine the inner cultivation with the outer one, and static exercise with dynamic exercise; and (4) with regard to the ways of treatment of diseases, to combine the Daoist medicine with the Western medicine. (shrink)

The original meaning of the term Dao is a road. As the Explanation of the Characters says, "What we walk on is a way [Dao]." The character is derived from two parts: shou, a head, and chuo, to walk and stop and walk again—that is, to walk. The head indicates the way to go and the body walks in this direction. Later, the term Dao was extended in meaning from the concrete to the general, gradually becoming a more general and (...) abstract word. Thus it took on the sense of norm, law, -ism, guide, method, and technique. Yet all these meanings are still consonant with the original sense of the Way. In Laozi's time, most thinkers had not raised Dao to become a wholly independent philosophical concept. It was still a limited thing; thus, we find "the Way of heaven," "the Way of human beings," and "the Way of spirits.". (shrink)

This article gives a holistic re-examination of the semantic content and syntactic structure of the concept of relative identity: it suggests and explains an expanded and enhanced dual-track characterization of relative identity. It is expanded in this sense: its due coverage is not narrowly restricted to the equal-status case of identity statements (the symmetric case for identity simplex) but also includes the category-assimilating case (the asymmetric case for identity complex), both of which are unified by the shared semantic core content (...) of relative identity. It is enhanced in this sense: it is intended to give a more refined characterization of relative identity for the sake of enhancing our understanding of the structure and content of real-life relative-identity statements in people’s basic employment of language in view of the relation between thought, language, and the world. (shrink)

How are Chinese philosophy and analytic philosophy-two very distinct traditions-alike? In this volume, fifteen distinguished scholars compare and contrast the methodologies, finding areas in which each tradition can learn from, contribute to, and complement the other.

This book is an inquiry into the philosophical concern with truth as one joint subject in philosophy of language and metaphysics and presents a theory of truth, substantive perspectivism (SP). Emphasizing our basic pre-theoretic understanding of truth (i.e., what is captured by the axiomatic thesis of truth that the nature of truth consists in capturing the way things are), and in the deflationism vs. substantivism debate background, SP argues for the substantive nature of non-linguistic truth and its notion’s indispensable substantive (...) explanatory role, both of which are not only intrinsically beyond what the linguistic function of the truth predicate can tell but are fundamentally related to the raison d’être of the truth predicate. Taking a holistic approach, SP endeavors to do justice to various reasonable perspectives, which are somehow contained in many competing accounts of truth, through a coordinate system: SP interprets such perspectives as distinct but related perspective-elaboration principles that distinctively (regarding distinct dimensions of the truth concern and/or for the sake of distinct purposes) elaborate, but are also unified by, the truth axiom thesis. To look at the issue from a broader vision, the book also takes a cross-tradition approach exploring the relationship between Daoist thinking of truth and thinking about truth in analytic philosophy.This book will enhance our systematic understanding of the issue through its holistic approach, broaden our vision on the issue via its cross-tradition approach, and enrich the conceptual and explanatory resources in treating the issue. (shrink)

Through a comparative case analysis regarding the Chinese language, it is discussed how the structure and functions of a natural language would bear upon the ways in which some philosophical problems are posed and some ontological insights shaped. Disagreeing with Chad Hansen's mass-noun hypothesis, a collective-noun hypothesis is argued for: (1) the denotational semantics and relevant grammatical features of Chinese nouns are like those of collective nouns; (2) their implicit ontology is a mereological ontology of collection-of-individuals with both part-whole and (...) member-class structure; and (3) encouraged and shaped by the folk semantics of Chinese nouns, classical Chinese theorists of language take this kind of mereological nominalism for granted. (shrink)

本书论述中国哲学之特殊性问题、儒家系统之性格、法家所开出的政治格局之意义、佛教中圆教底意义、宋明儒学概述等。.

This book presents a systematic unifying-pluralist account--a "constructive-engagement" account--of how cross-tradition engagement in philosophy is possible. The goal of this "constructive-engagement" account is, by way of reflective criticism, argumentation, and methodological guiding principles, to inquire into how distinct approaches from different philosophical traditions can talk to and learn from each other for the sake of making joint contributions to the contemporary development of philosophy. In Part I of the book, Bo Mou explores a range of fundamental theoretic and methodological issues (...) in cross-tradition philosophical engagement and philosophical interpretation. In Part II, he analyzes several representative case studies that demonstrate how relevant resources in the Western and Chinese philosophical traditions can constructively engage with each other. These studies cover issues in philosophical methodology, metaphysics, epistemology, philosophy of language and logic, and ethics. The book's theoretical and practical approaches expand the vision, coverage, and agenda of doing philosophy comparatively, and promote worldwide joint efforts of cross-tradition philosophical inquiries. Cross-Tradition Engagement in Philosophy will be of interest to graduate students and scholars interested in comparative philosophy and the intersection of Chinese and Western philosophy. It will also appeal to those who are interested in the ways in which cross-tradition philosophical engagement can enhance contemporary philosophical debates in metaphysics, epistemology, philosophy of language and logic, and ethics. (shrink)