Brain‐derived neurotrophic factor (BDNF) is the most‐abundant neurotrophin in the brain. In mammals, it is synthesized as a precursor called proBDNF, which is proteolytically cleaved to generate mature BDNF. The BDNF gene is located on chromosome 11p13, and a functional single nucleotide polymorphism (SNP) of this gene has been shown to produce a valine (Val)‐to‐methionine (Met) substitution in the proBDNF protein at codon 66 (Val66Met). Several papers suggest that this SNP is related to decreased hippocampal volume and hippocampus‐mediated memory performance (...) in humans. Recently, Chen et al.1 generated a variant BDNF mouse (BDNFMet/Met) that reproduces the phenotypic hallmarks in humans with a variant Met allele. In the behavioral analysis, BDNFMet/Met mice show increased anxiety‐related behaviors. This mini‐review examines the impact of Met substitution of proBDNF on anxiety‐related behaviors. BioEssays 29: 116–119, 2007. © 2007 Wiley Periodicals, Inc. (shrink)

9.11以後に、もう一つの世界は可能か?善き帝国の世界を構想する倫理的実践の試み。.

Reinforcement learning has recently received much attention as a learning method for complicated systems, e.g., robot systems. It does not need prior knowledge and has higher capability of reactive and adaptive behaviors. However increase in dimensionality of the action-state space makes it diffcult to accomplish learning. The applicability of the existing reinforcement learning algorithms are effective for simple tasks with relatively small action-state space. In this paper, we propose a new reinforcement learning algorithm: “Q-learning with Dynamic Structuring of Exploration Space (...) Based on Genetic Algorithm ”. The algorithm is applicable to systems with high dimensional action and interior state spaces, for example a robot with many redundant degrees of freedom. To demonstrate the effectiveness of the proposed algorithm simulations of obstacle avoidance by a 50 links manipulator have been carried out. It is shown that effective behavior can be learned by using the proposed algorithm. (shrink)

The main theme of volume 6 of Eco-ethica is "Ethics and Justice" which focuses on the idea of "justice" in a metaphysical, social, and personal sense. Justice is considered as a balance between opposite ambitions in interdependent persons, and as equity in legislation, but not as blind justice. Today it is valuable not only on the national, but also on the cosmopolitan level. Before it became personal justice, the idea of justice was considered metaphysical and social, both in European and (...) Chinese culture. However, in modern times, it is often reduced to a moral duty without meta-ethical responsibility. The last section considers the importance of the philosophy of Paul Ricoeur (1913-2005) for clarifying the idea of justice. (Series: Eco-Ethica, Vol. 6) [Subject: Philosophy, Ethics]. (shrink)

Prediction is essential for the efficiency of many cognitive processes; however, this process is not always perfect. Predictive coding theory suggests that the brain generates and updates a prediction to respond to an upcoming event. Although an electrophysiological index of prediction, the stimulus preceding negativity, has been reported, it remains unknown whether the SPN reflects the prediction accuracy, or whether it is associated with the prediction error, which corresponds to a mismatch between a prediction and an actual input. Thus, the (...) present study aimed to investigate this question using electroencephalography. Participants were asked to predict the original pictures from pictures that had undergone different levels of pixelation. The SPN amplitude was affected by the level of pixelation and correlated with the subjective evaluation of the prediction accuracy. Furthermore, late positive components were negatively correlated with SPN. These results suggest that the amplitude of SPN reflects the prediction accuracy; more accurate prediction increases the SPN and reduces the prediction error, resulting in reduced LPC amplitudes. (shrink)

Reinforcement learning is very effective for robot learning. Because it does not need priori knowledge and has higher capability of reactive and adaptive behaviors. In our previous works, we proposed new reinforcement learning algorithm: “Q-learning with Dynamic Structuring of Exploration Space Based on Genetic Algorithm (QDSEGA)”. It is designed for complicated systems with large action-state space like a robot with many redundant degrees of freedom. And we applied it to 50 link manipulator and effective behavior is acquired. However optimality and (...) fault tolerance of the proposed algorithm were not considered and to demonstrate effectiveness of the proposed algorithm other applications are necessary. Acquiring of locomotion patterns by a multi-legged robot is a very interesting problem. As it has many redundant degrees of freedom, application of usual reinforcement learning is difficult and an optimal locomotion has not been acquired using previous reinforcement learning algorithm. And the redundancy of the robot is effective to the fault tolerance and various locomotion patterns can be acquired for adapting the faults of the legs. In this paper, we applied QDSEGA to acquiring of locomotion pattern by the multi-legged robot and considered the optimality and fault tolerance. Effective behavior has been obtained by using our proposed algorithm. (shrink)

It has been suggested that hierarchically structured symbols, a remarkable feature of human language, are produced via the operation of recursive combination. Recursive combination is frequently observed in human behavior, not only in language but also in action sequences, mind-reading, technology, et cetera.; in contrast, it is rarely observed in animals. Why is it that only humans use this operation? What is the adaptability of recursive combination? We aim (1) to identify the environmental feature(s) in which recursive combination is effective (...) for survival and reproduction, and that has facilitated the evolution of this ability, and (2) to demonstrate the possible evolutionary processes of recursive combination. To achieve this, we constructed an evolutionary simulation of agents that generated products using recursive combination and used the results to explore the types of fitness functions (that reflect the kinds of adaptive environments) that give rise to this ability. We identified two types of adaptability of the recursive combination: (1) diversifiability of production and (2) diversifiability of products. Through the former, recursive combination promotes robustness against failure of production caused by inaccurate manipulations or irreversible changes. In an environment in which diversified products are preferable, sharing a portion of the production process for these products entails producing multiple products in which recursive combination plays a key role. We suppose that recursive combination works as a driving force of material culture. Finally, we discuss the possible evolutionary scenarios of recursive combination that is later generalized to encompass many aspects of human cognition, including human language. (shrink)

We investigated the effect of culture, moral discourse, and motivation to engage in prosocial behavior on benefactors’ positive affect. Participants from three cultures responded to scenarios in which they could perform small acts of kindness for different targets. A stronger relationship between agentic and obligated motivation to perform acts of kindness, as well as between obligated motivation and positive affect, was observed for participants from Japan, and for individuals with higher endorsement of the Community Ethic. Agentic motivation to engage in (...) prosocial behavior was related to benefactors’ positive affect, regardless of relationship type. (shrink)

In the trolley problem, a well-known moral dilemma, the intuitive process is believed to increase deontological judgments, while deliberative reasoning is thought to promote utilitarian decisions. Therefore, based on the dual-process model, there seems to be an attempt to save several lives at the expense of a few others in a deliberative manner. This study examines the validity of this argument. To this end, we manipulate decision-making time in the standard trolley dilemma to compare differences among 119 Japanese female undergraduates (...) under three conditions: intuitive judgment, deliberative judgment, and judgment after a group discussion. The current results demonstrate that utilitarian judgments decreased from 52.9% in the intuition condition to 43.7% in the deliberation condition and 37.0% after the discussion. Additional analysis suggests that the decrease in utilitarian judgments may be related to psychological unwillingness to assume responsibility for the lives of others rather than to an increase in deontological judgments. Finally, these results are discussed from an adaptationist perspective. (shrink)

Quelle est la nature de la liberté réelle (réelle) dans notre société? Je présenterai ici une nouvelle théorie du libéralisme que j’appelle « libéralisme orienté vers la croissance ». D’abord, j’examine le concept de liberté positive et négative d’Isaiah Berlin et je pose la question fondamentale en matière de liberté, à savoir que la liberté est un idéal paradoxal. J’identifierai deux paradoxes : l’un porte sur la liberté ordinaire et les valeurs sophistiquées, l’autre sur la question de la libération et (...) de l’apathie des individus ou des populations. Comment pouvons-nous surmonter ces paradoxes? Pour répondre à cette question, j’examinerai l’argument de Charles Taylor sur la liberté positive (liberté) et en élargirai les implications. Le paradoxe est d’autant plus lorsqu’il s’agit de communautés, comme la société japonaise. Au-delà du mode de pensée communautaire de Taylor, par exemple, je construis une nouvelle théorie de la liberté en proposant de suivre trois principes : le principe de la vertu (estime de soi), le principe du changement générateur et le principe de la différenciation. Je soutiens que la pierre de touche d’une société libre dépend de la façon dont nous concevons notre gouvernance sociale sur la base de ces principes. JEL Codes : Z10, B25. (shrink)

No início do movimento psicanalítico, a Hungria foi um dos países pioneiros dentre os que acolheram e propagaram a psicanálise. Sándor Ferenczi, figura principal de desenvolvimento da psicanálise no país, abraçou a causa psicanalítica e se tornou um dos mais importantes teóricos de sua história. Responsável pela criação da Associação Psicanalítica Internacional, fundaria também a Sociedade Húngara de Psicanálise, instituição reconhecida pela originalidade de suas propostas. Além de Ferenczi, Melanie Klein, Michael e Alice Balint, Géza Roheim, dentre outros, foram seus (...) membros. Neste estudo de caráter histórico, o intuito é retomar todo o caminho trilhado pela instituição húngara, desde sua fundação até sua dissolução, em 1949. A identidade e o “espírito” investigativo daquela instituição se perpetuariam ao longo da história psicanalítica, influenciando, direta ou indiretamente, grandes escolas e teóricos da psicanálise, como D. W. Winnicott e alguns pensadores das escolas americanas e francesas. Palavras-chave: psicanálise; história da psicanálise; sociedade húngara de psicanálise; instituições psicanalíticas; Sándor Ferenczi.: Hungary was a place where psychoanalysis founded a great support and development at the beginning of psychoanalytical movement. Sándor Ferenczi, leading figure of psychoanalytical increase in the country, embraced the psychoanalytic cause and became one of its most important theorists and thinkers in history. Responsible for the foundation of the International Psychoanalytical Association, also created the Hungarian Psychoanalytical Society, an institution recognized for the originality of their proposals. Besides Ferenczi, Melanie Klein, Michael and Alice Balint, Géza Roheim, among others, were its members. In this historical study, the purpose is to resume the entire path taken by the Hungarian institution, from the foundation to its dissolution in 1949. The identity and the investigative “spirit” of that institution perpetuate throughout psychoanalytical history, influencing, directly or indirectly, great schools and theorists of psychoanalysis, eg, D. W. Winnicott and some thinkers of American and French schools. Keywords: psychoanalysis; psychoanalytical history; hungarian psychoanalytical society; psychoanalytical institutions; Sándor Ferenczi. (shrink)

ABSTRACT Studies on development and fairness judgments in resource allocations have mainly addressed the distribution of reward. However, the distribution of responsibility also requires exploration in the context of research on development and distributive justice. For an integrated understanding of reward and responsibility distributions, we briefly reviewed the studies on children’s fairness judgments in reward and responsibility distributions. We then discussed the theoretical basis and methodological framework to further our understanding. After reviewing a study which considered both reward and responsibility (...) distributions in the same experiment, we also discussed the questions to be solved to understand children’s fairness judgments in both types of distributions. Individual developmental process of fairness judgments, (in)consistency of judgments in reward and responsibility distributions, and generous judgments in allocations were discussed by referring to theoretical discussions of culture and reciprocity. (shrink)

Drawing on recent work in the contemporary philosophy of economics, this book presents new ideas on liberalism, including the concept of 'growth-oriented liberalism'. Since the end of the Cold War, questions and definitions of liberalism have moved from the sphere of political systems (the socialism versus liberalism debates) to the sphere of ethics (what it means to live in a liberal society). The chapters in this work trace the trajectory of the concept of liberalism in the philosophy of economics by (...) exploring the ideological implications of the methodological debate between socialism and liberalism, the idea of liberty as real freedom, the ethical implications of Max Weber's methodology on autonomy and liberty, and new typological theories of ideologies in the context of contemporary economic ethics. This book marks a significant contribution to the literature on liberalism in the philosophy of economics and economic methodology, and is highly recommended for readers who seek updated ideas on liberal society in its ethical and philosophical contexts. Tsutomu Hashimoto is a Professor at Hokkaido University and the President of the Synodos Institute of International Studies in Japan. (shrink)

The world’s population is currently aging, and the issue of ageism has become serious worldwide, including in Japan. Negative attitudes toward older adults can have undesirable effects on the mental and physical health of this group. We focused on the effects of contact experience with older adults and germ aversion, or the degree of aversion to infection, on negative attitudes toward older adults. Additionally, we included a moderating variable; youth identity, or the sense of belonging with younger rather than older (...) age groups. An online survey was conducted with Japanese participants. We conducted multiple regression analyses and the results showed that the interaction effect between youth identity and contact experience on negative attitudes toward older adults was significant. The findings suggest that contact experience may help in reducing negative attitudes toward older adults among people with low youth identity. The interaction effect between youth identity and germ aversion, however, was not significant. Academic research on the effects of some psychological interventions should pay particular attention to the role of youth identity. Future directions for empirical studies are also discussed. (shrink)

The purpose of the current study was to examine the influence of individuals’ help-seeking preference and their collective perception of the organizational climate in school on teachers’ mental health. Previous studies demonstrated that HSP was negatively associated with risk of burnout, suggesting that teachers who hesitate to seek help from their colleagues are more likely to have mental health problems. Thus, the current study hypothesized that a collegial organizational climate would be negatively associated with burnout. To test this hypothesis, we (...) developed a scale to measure schoolteachers’ collective perception of their organizational climate, and the newly developed scale was used to assess its relationship with HSP and teachers’ burnout risk. The results demonstrated that younger teachers, a low level of help-seeking, and a less collaborative climate increased the risk of burnout. The results also showed a significant interaction effect, indicating that HSP was less closely associated with teachers’ burnout risk if their organization was perceived as having a collegial climate. These findings clearly show how the social environment of a school’s organizational climate can affect schoolteachers’ mental health in Japan. (shrink)

古事類苑、モラロジー、麗澤大学...研究遍歴と交友関係を改めて検討し、道徳の科学的研究に至る過程を描き出す。.

In the circular sphere around the Pacific Ocean many volcanos have erupted, and, because of tectonic plates, numerous earthquakes have occurred. In Tonga, especially, the resulting devastation has been beyond our wildest imagination. Regarding such natural phenomena, we could not predict anything. Likewise, the Covid-19 pandemic appeared suddenly, and no one can say when its destruction will end. Protective measures against infection have affected the nature of our social interactions: masking has changed our spatial consciousness; observing social distancing has made (...) us less dependent on one another and has influenced us to seek solitude. As a result, inter-subjectivity—the foundation of ethics—has been broken. All of these effects on our interpersonal relationships have instilled in us a new attitude towards nature, because the human being is a part of nature. This new attitude with nature opens up a new paradigm: dialogues with nature and their co-operative activities must be demanded, and we must wait for nature’s movement and ask for its help. It is, in a way, the traditional artistic attitude toward nature. (shrink)

Avec et après la pandémie, notre conscience de l’espace et du temps a subi un changement radical : les individus ont expérimenté l’oisiveté forcée, les gestes barrières et la distanciation physique qui redouble l’éloignement induit par les nouvelles technologies ayant substitué la communication à l’échange. Or, les progrès techniques n’ont de progrès que le nom et ne cherchent que l’efficacité assurée par la vitesse qui fait violence aux cycles de la nature. Pourtant, seule cette dernière est capable de nous réconcilier (...) avec nous-mêmes en nous extrayant de la domination de la machine et en nous enseignant la patience de laquelle peut surgir la beauté : beauté du geste artistique qui défie le temps, accès à la transcendance à travers la contemplation du vivant. C’est dans ce rapport d’interdépendance avec la nature que nous pouvons échapper à la déshumanisation de la société moderne et renouer avec la beauté du monde. (shrink)

ウェーバーの主題を発展的に継承し、社会を多元的に豊穣化するための来るべき人間像を彫琢する。.

Two studies aimed to examine cultural differences in social support provision, with or without solicitation, in Japan and the United States. In Study 1, we replicated a previous study with Japanese university students. We found that the Japanese participants did not provide social support when it was not solicited, as compared with when it was solicited. Furthermore, in Study 2, participants were asked to respond to a questionnaire regarding a hypothetical stressful situation experienced by a close other and to indicate (...) their willingness to provide support. We confirmed our hypothesis that Japanese participants hesitate to provide unsolicited support to close others, even when they recognize that the close others are in need, whereas the American participants do not hesitate to provide such support. Contrastingly, regarding solicited support, the Japanese and Americans were equally ready to provide support, as hypothesized. The cultural difference in social support resides in the provision of unsolicited support. These results suggest that differences in culturally appropriate responses to needy people are responsible for the difference in the provision of unsolicited vs. solicited social support. (shrink)